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Novel motif:136

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name:motif136_GTCTGCGTCTCT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 7.522400e-16
GO:0048266 behavioral response to pain 8.549039e-13
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 7.971425e-11
GO:0045994 positive regulation of translational initiation by iron 1.075178e-10
GO:0002037 negative regulation of L-glutamate transport 1.075178e-10
GO:0003009 skeletal muscle contraction 2.722083e-10
GO:0051533 positive regulation of NFAT protein import into nucleus 3.747504e-10
GO:0006447 regulation of translational initiation by iron 5.661582e-10
GO:0050881 musculoskeletal movement 9.332360e-10
GO:0002761 regulation of myeloid leukocyte differentiation 2.504013e-9
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 2.756526e-9
GO:0042506 tyrosine phosphorylation of Stat5 protein 6.929905e-9
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 8.475426e-9
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.124418e-8
GO:0002922 positive regulation of humoral immune response 1.656191e-8
GO:0051956 negative regulation of amino acid transport 1.828583e-8
GO:0030225 macrophage differentiation 2.354672e-8
GO:0002861 regulation of inflammatory response to antigenic stimulus 2.585420e-8
GO:0002920 regulation of humoral immune response 3.323776e-8
GO:0044236 multicellular organismal metabolic process 5.632153e-8
GO:0055093 response to hyperoxia 6.514266e-8
GO:0008625 induction of apoptosis via death domain receptors 7.068589e-8
GO:0010765 positive regulation of sodium ion transport 9.324983e-8
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 9.755443e-8
GO:0006958 complement activation, classical pathway 1.062444e-7
GO:0006956 complement activation 1.423207e-7
GO:0045662 negative regulation of myoblast differentiation 2.409421e-7
GO:0046985 positive regulation of hemoglobin biosynthetic process 2.486069e-7
GO:0043973 histone H3-K4 acetylation 2.486069e-7
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 2.486069e-7
GO:0060033 anatomical structure regression 2.917756e-7
GO:0061048 negative regulation of branching involved in lung morphogenesis 3.001939e-7
GO:0045835 negative regulation of meiosis 3.986964e-7
GO:0010868 negative regulation of triglyceride biosynthetic process 4.250076e-7
GO:0030574 collagen catabolic process 4.295102e-7
GO:0002573 myeloid leukocyte differentiation 4.764832e-7
GO:0010866 regulation of triglyceride biosynthetic process 5.083788e-7
GO:0045661 regulation of myoblast differentiation 5.174837e-7
GO:0090207 regulation of triglyceride metabolic process 5.795036e-7
GO:0045112 integrin biosynthetic process 6.262775e-7
GO:0006959 humoral immune response 6.467553e-7
GO:0002455 humoral immune response mediated by circulating immunoglobulin 6.676489e-7
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 7.394014e-7
GO:0046108 uridine metabolic process 7.394014e-7
GO:0032929 negative regulation of superoxide anion generation 8.104019e-7
GO:0010625 positive regulation of Schwann cell proliferation 8.626079e-7
GO:0044243 multicellular organismal catabolic process 8.724804e-7
GO:0060319 primitive erythrocyte differentiation 1.106258e-6
GO:0002575 basophil chemotaxis 1.106258e-6
GO:0048771 tissue remodeling 1.157032e-6
GO:0048705 skeletal system morphogenesis 1.286591e-6
GO:0030828 positive regulation of cGMP biosynthetic process 1.407292e-6
GO:0060351 cartilage development involved in endochondral bone morphogenesis 1.435164e-6
GO:0002678 positive regulation of chronic inflammatory response 1.453326e-6
GO:0045760 positive regulation of action potential 1.471725e-6
GO:0044259 multicellular organismal macromolecule metabolic process 1.476664e-6
GO:0035441 cell migration involved in vasculogenesis 1.987525e-6
GO:0071347 cellular response to interleukin-1 2.030038e-6
GO:0001300 chronological cell aging 2.396258e-6
GO:0030852 regulation of granulocyte differentiation 2.431516e-6
GO:0032963 collagen metabolic process 2.566136e-6
GO:0045948 positive regulation of translational initiation 2.588982e-6
GO:0030224 monocyte differentiation 2.768941e-6
GO:0051216 cartilage development 2.865795e-6
GO:0002676 regulation of chronic inflammatory response 3.126844e-6
GO:0030826 regulation of cGMP biosynthetic process 3.244845e-6
GO:0051023 regulation of immunoglobulin secretion 3.639656e-6
GO:0003417 growth plate cartilage development 3.756841e-6
GO:0035304 regulation of protein dephosphorylation 3.992101e-6
GO:0030100 regulation of endocytosis 4.028738e-6
GO:0042508 tyrosine phosphorylation of Stat1 protein 4.348303e-6
GO:0002036 regulation of L-glutamate transport 4.610084e-6
GO:0002230 positive regulation of defense response to virus by host 5.049448e-6
GO:0045649 regulation of macrophage differentiation 5.075987e-6
GO:0050830 defense response to Gram-positive bacterium 5.254720e-6
GO:0003416 endochondral bone growth 5.724888e-6
GO:0051971 positive regulation of transmission of nerve impulse 5.771541e-6
GO:0001894 tissue homeostasis 6.501925e-6
GO:0035356 cellular triglyceride homeostasis 6.929625e-6
GO:2000097 regulation of smooth muscle cell-matrix adhesion 7.213027e-6
GO:0046849 bone remodeling 7.228061e-6
GO:0090279 regulation of calcium ion import 7.430299e-6
GO:0031646 positive regulation of neurological system process 7.573561e-6
GO:0035725 sodium ion transmembrane transport 8.173506e-6
GO:0006540 glutamate decarboxylation to succinate 8.388227e-6
GO:0050806 positive regulation of synaptic transmission 8.623676e-6
GO:0002016 regulation of blood volume by renin-angiotensin 1.027815e-5
GO:0048265 response to pain 1.075568e-5
GO:0042391 regulation of membrane potential 1.102926e-5
GO:0002028 regulation of sodium ion transport 1.107040e-5
GO:0035305 negative regulation of dephosphorylation 1.293095e-5
GO:0045651 positive regulation of macrophage differentiation 1.330163e-5
GO:0060696 regulation of phospholipid catabolic process 1.360186e-5
GO:0090209 negative regulation of triglyceride metabolic process 1.368547e-5
GO:0030853 negative regulation of granulocyte differentiation 1.387286e-5
GO:0043982 histone H4-K8 acetylation 1.395763e-5
GO:0043981 histone H4-K5 acetylation 1.395763e-5
GO:0072277 metanephric glomerular capillary formation 1.404737e-5
GO:0046684 response to pyrethroid 1.522882e-5
GO:0046984 regulation of hemoglobin biosynthetic process 1.535217e-5
GO:0035272 exocrine system development 1.567374e-5
GO:0007422 peripheral nervous system development 1.638115e-5
GO:0035036 sperm-egg recognition 1.647962e-5
GO:0006707 cholesterol catabolic process 1.701812e-5
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 1.728507e-5
GO:0002675 positive regulation of acute inflammatory response 1.769565e-5
GO:0090197 positive regulation of chemokine secretion 1.849802e-5
GO:0032754 positive regulation of interleukin-5 production 1.856757e-5
GO:0007296 vitellogenesis 1.864182e-5
GO:0043271 negative regulation of ion transport 1.931487e-5
GO:0034502 protein localization to chromosome 1.975542e-5
GO:0035306 positive regulation of dephosphorylation 1.991649e-5
GO:0001508 regulation of action potential 2.598686e-5
GO:0035307 positive regulation of protein dephosphorylation 2.606281e-5
GO:0002316 follicular B cell differentiation 2.766017e-5
GO:0070079 histone H4-R3 demethylation 2.805420e-5
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 2.805420e-5
GO:0070078 histone H3-R2 demethylation 2.805420e-5
GO:0035117 embryonic arm morphogenesis 2.903728e-5
GO:0016337 cell-cell adhesion 2.964604e-5
GO:0048661 positive regulation of smooth muscle cell proliferation 3.060556e-5
GO:0051798 positive regulation of hair follicle development 3.174250e-5
GO:0060688 regulation of morphogenesis of a branching structure 3.177141e-5
GO:0045926 negative regulation of growth 3.189472e-5
GO:0010624 regulation of Schwann cell proliferation 3.200927e-5
GO:0060591 chondroblast differentiation 3.203771e-5
GO:0071585 detoxification of cadmium ion 3.264995e-5
GO:0060561 apoptosis involved in morphogenesis 3.311787e-5
GO:0002673 regulation of acute inflammatory response 3.417763e-5
GO:0071670 smooth muscle cell chemotaxis 3.617574e-5
GO:0060981 cell migration involved in coronary angiogenesis 3.617574e-5
GO:0060977 coronary vasculature morphogenesis 3.670868e-5
GO:0039020 pronephric nephron tubule development 3.819140e-5
GO:0035565 regulation of pronephros size 3.819140e-5
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 3.819140e-5
GO:0002763 positive regulation of myeloid leukocyte differentiation 4.337298e-5
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 4.352238e-5
GO:0033138 positive regulation of peptidyl-serine phosphorylation 4.454909e-5
GO:0007159 leukocyte cell-cell adhesion 4.651787e-5
GO:0090196 regulation of chemokine secretion 4.713301e-5
GO:0009988 cell-cell recognition 4.801379e-5
GO:0060349 bone morphogenesis 4.968972e-5
GO:0048167 regulation of synaptic plasticity 4.980550e-5
GO:0052565 response to defense-related host nitric oxide production 5.172985e-5
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 5.438563e-5
GO:0060754 positive regulation of mast cell chemotaxis 5.489578e-5
GO:0005984 disaccharide metabolic process 5.504230e-5
GO:0046902 regulation of mitochondrial membrane permeability 5.620597e-5
GO:0072333 signal transduction by p53 class mediator resulting in induction of anoikis 5.822904e-5
GO:0042088 T-helper 1 type immune response 6.107849e-5
GO:0071258 cellular response to gravity 6.148238e-5
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion 6.148238e-5
GO:0061044 negative regulation of vascular wound healing 6.148238e-5
GO:0035491 positive regulation of leukotriene production involved in inflammatory response 6.148238e-5
GO:0045721 negative regulation of gluconeogenesis 6.176447e-5
GO:0010900 negative regulation of phosphatidylcholine catabolic process 6.212092e-5
GO:0071803 positive regulation of podosome assembly 6.501432e-5
GO:0044403 symbiosis, encompassing mutualism through parasitism 6.749871e-5
GO:0006972 hyperosmotic response 6.849706e-5
GO:0015696 ammonium transport 7.030656e-5
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 7.363607e-5
GO:0001798 positive regulation of type IIa hypersensitivity 7.530817e-5
GO:2000465 regulation of glycogen (starch) synthase activity 7.558826e-5
GO:0045684 positive regulation of epidermis development 7.627874e-5
GO:0043088 regulation of Cdc42 GTPase activity 7.627874e-5
GO:0045940 positive regulation of steroid metabolic process 7.712811e-5
GO:0032241 positive regulation of nucleobase-containing compound transport 7.968894e-5
GO:0030099 myeloid cell differentiation 8.363688e-5
GO:0007612 learning 8.690512e-5
GO:0018125 peptidyl-cysteine methylation 8.846764e-5
GO:0002712 regulation of B cell mediated immunity 8.888760e-5
GO:0001649 osteoblast differentiation 8.992037e-5
GO:0071168 protein localization to chromatin 9.220285e-5
GO:0045453 bone resorption 9.584711e-5
GO:0002889 regulation of immunoglobulin mediated immune response 9.878664e-5
GO:0071456 cellular response to hypoxia 9.905880e-5
GO:0060557 positive regulation of vitamin D biosynthetic process 1.015599e-4
GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback 1.017937e-4
GO:0048742 regulation of skeletal muscle fiber development 1.018877e-4
GO:0072385 minus-end-directed organelle transport along microtubule 1.019970e-4
GO:0033135 regulation of peptidyl-serine phosphorylation 1.027888e-4
GO:0072376 protein activation cascade 1.029498e-4
GO:0002762 negative regulation of myeloid leukocyte differentiation 1.036811e-4
GO:2000369 regulation of clathrin-mediated endocytosis 1.071015e-4
GO:0010959 regulation of metal ion transport 1.079568e-4
GO:0060291 long-term synaptic potentiation 1.085874e-4
GO:0060627 regulation of vesicle-mediated transport 1.095791e-4
GO:0060693 regulation of branching involved in salivary gland morphogenesis 1.118712e-4
GO:0051701 interaction with host 1.181871e-4
GO:0006538 glutamate catabolic process 1.188146e-4
GO:0060348 bone development 1.206357e-4
GO:0090281 negative regulation of calcium ion import 1.214602e-4
GO:0071584 negative regulation of zinc ion import 1.214602e-4
GO:0051497 negative regulation of stress fiber assembly 1.226714e-4
GO:0048026 positive regulation of nuclear mRNA splicing, via spliceosome 1.234494e-4
GO:0002274 myeloid leukocyte activation 1.268550e-4
GO:0006534 cysteine metabolic process 1.270946e-4
GO:0002250 adaptive immune response 1.288963e-4
GO:0006998 nuclear envelope organization 1.327589e-4
GO:0042117 monocyte activation 1.359231e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.378858e-4
GO:0032571 response to vitamin K 1.384215e-4
GO:0000413 protein peptidyl-prolyl isomerization 1.428750e-4
GO:0034765 regulation of ion transmembrane transport 1.464829e-4
GO:0032959 inositol trisphosphate biosynthetic process 1.515388e-4
GO:0060087 relaxation of vascular smooth muscle 1.553135e-4
GO:0044319 wound healing, spreading of cells 1.565453e-4
GO:0045670 regulation of osteoclast differentiation 1.613572e-4
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.666213e-4
GO:0001933 negative regulation of protein phosphorylation 1.679703e-4
GO:0070482 response to oxygen levels 1.680023e-4
GO:0019048 virus-host interaction 1.708925e-4
GO:0035573 N-terminal peptidyl-serine trimethylation 1.713694e-4
GO:0035572 N-terminal peptidyl-serine dimethylation 1.713694e-4
GO:0018012 N-terminal peptidyl-alanine trimethylation 1.713694e-4
GO:0018016 N-terminal peptidyl-proline dimethylation 1.713694e-4
GO:0016226 iron-sulfur cluster assembly 1.733594e-4
GO:0046732 active induction of host immune response by virus 1.757880e-4
GO:0035313 wound healing, spreading of epidermal cells 1.764932e-4
GO:0051055 negative regulation of lipid biosynthetic process 1.791136e-4
GO:0035771 interleukin-4-mediated signaling pathway 1.888063e-4
GO:0061037 negative regulation of cartilage development 1.955974e-4
GO:0046730 induction of host immune response by virus 1.981065e-4
GO:0043269 regulation of ion transport 1.981109e-4
GO:0071034 CUT catabolic process 2.040942e-4
GO:0045541 negative regulation of cholesterol biosynthetic process 2.040942e-4
GO:0015747 urate transport 2.042891e-4
GO:0045630 positive regulation of T-helper 2 cell differentiation 2.149915e-4
GO:0007435 salivary gland morphogenesis 2.152127e-4
GO:0001502 cartilage condensation 2.193421e-4
GO:0003073 regulation of systemic arterial blood pressure 2.217906e-4
GO:0005989 lactose biosynthetic process 2.237728e-4
GO:0044140 negative regulation of growth of symbiont on or near host surface 2.382025e-4
GO:0071316 cellular response to nicotine 2.404254e-4
GO:0002883 regulation of hypersensitivity 2.404563e-4
GO:0019228 regulation of action potential in neuron 2.413770e-4
GO:0010739 positive regulation of protein kinase A signaling cascade 2.423973e-4
GO:0052200 response to host defenses 2.494593e-4
GO:0042503 tyrosine phosphorylation of Stat3 protein 2.503502e-4
GO:0045918 negative regulation of cytolysis 2.515915e-4
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.607233e-4
GO:0048569 post-embryonic organ development 2.642152e-4
GO:0048873 homeostasis of number of cells within a tissue 2.646193e-4
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 2.742226e-4
GO:0061157 mRNA destabilization 2.742226e-4
GO:0043060 meiotic metaphase I plate congression 2.755799e-4
GO:0051324 prophase 2.783953e-4
GO:0001569 patterning of blood vessels 2.808703e-4
GO:0010872 regulation of cholesterol esterification 2.845856e-4
GO:0043983 histone H4-K12 acetylation 2.849631e-4
GO:0019226 transmission of nerve impulse 2.872664e-4
GO:0035308 negative regulation of protein dephosphorylation 2.931081e-4
GO:0051935 glutamate uptake involved in synaptic transmission 2.937607e-4
GO:2000273 positive regulation of receptor activity 2.957704e-4
GO:0010873 positive regulation of cholesterol esterification 2.974223e-4
GO:0015914 phospholipid transport 3.001904e-4
GO:0060020 Bergmann glial cell differentiation 3.038538e-4
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 3.053425e-4
GO:0061098 positive regulation of protein tyrosine kinase activity 3.141084e-4
GO:0046886 positive regulation of hormone biosynthetic process 3.173342e-4
GO:0001970 positive regulation of activation of membrane attack complex 3.186790e-4
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 3.296321e-4
GO:0032958 inositol phosphate biosynthetic process 3.355765e-4
GO:0043089 positive regulation of Cdc42 GTPase activity 3.368609e-4
GO:0070345 negative regulation of fat cell proliferation 3.521718e-4
GO:0008050 female courtship behavior 3.521718e-4
GO:0042823 pyridoxal phosphate biosynthetic process 3.521718e-4
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 3.559140e-4
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.633378e-4
GO:0008298 intracellular mRNA localization 3.676896e-4
GO:2000370 positive regulation of clathrin-mediated endocytosis 3.710786e-4
GO:0032900 negative regulation of neurotrophin production 3.710786e-4
GO:0032244 positive regulation of nucleoside transport 3.710786e-4
GO:0032462 regulation of protein homooligomerization 3.732147e-4
GO:0007338 single fertilization 3.805929e-4
GO:0001654 eye development 3.846828e-4
GO:0003333 amino acid transmembrane transport 3.897767e-4
GO:0034389 lipid particle organization 3.950326e-4
GO:0001990 regulation of systemic arterial blood pressure by hormone 3.965293e-4
GO:0070483 detection of hypoxia 3.973934e-4
GO:0060628 regulation of ER to Golgi vesicle-mediated transport 4.032777e-4
GO:0007161 calcium-independent cell-matrix adhesion 4.032777e-4
GO:0072236 metanephric loop of Henle development 4.040828e-4
GO:0072329 monocarboxylic acid catabolic process 4.056302e-4
GO:0050804 regulation of synaptic transmission 4.089790e-4
GO:0040040 thermosensory behavior 4.092167e-4
GO:0001503 ossification 4.104718e-4
GO:0006422 aspartyl-tRNA aminoacylation 4.169941e-4
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 4.226973e-4
GO:0071460 cellular response to cell-matrix adhesion 4.229404e-4
GO:0071312 cellular response to alkaloid 4.251770e-4
GO:0006105 succinate metabolic process 4.304918e-4
GO:0006303 double-strand break repair via nonhomologous end joining 4.331912e-4
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 4.344030e-4
GO:0007339 binding of sperm to zona pellucida 4.465337e-4
GO:0033700 phospholipid efflux 4.492300e-4
GO:0001501 skeletal system development 4.508340e-4
GO:0051899 membrane depolarization 4.511175e-4
GO:0021523 somatic motor neuron differentiation 4.514978e-4
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 4.547028e-4
GO:0042552 myelination 4.569812e-4
GO:0050764 regulation of phagocytosis 4.569957e-4
GO:0048871 multicellular organismal homeostasis 4.759293e-4
GO:0035524 proline transmembrane transport 4.807488e-4
GO:0035303 regulation of dephosphorylation 4.857445e-4
GO:0032800 receptor biosynthetic process 4.945970e-4
GO:0010669 epithelial structure maintenance 5.275958e-4
GO:0031017 exocrine pancreas development 5.291726e-4
GO:0048671 negative regulation of collateral sprouting 5.483069e-4
GO:0045936 negative regulation of phosphate metabolic process 5.602086e-4
GO:0046325 negative regulation of glucose import 5.654834e-4
GO:0050957 equilibrioception 5.696896e-4
GO:0045986 negative regulation of smooth muscle contraction 5.732237e-4
GO:0001843 neural tube closure 5.848691e-4
GO:0002885 positive regulation of hypersensitivity 5.942742e-4
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 5.988649e-4
GO:0055012 ventricular cardiac muscle cell differentiation 6.084390e-4
GO:0051969 regulation of transmission of nerve impulse 6.114722e-4
GO:0009062 fatty acid catabolic process 6.163983e-4
GO:0045123 cellular extravasation 6.244986e-4
GO:0007184 SMAD protein import into nucleus 6.327971e-4
GO:0051797 regulation of hair follicle development 6.404165e-4
GO:0007214 gamma-aminobutyric acid signaling pathway 6.505334e-4
GO:0030260 entry into host cell 6.565039e-4
GO:0006873 cellular ion homeostasis 6.623102e-4
GO:0072239 metanephric glomerulus vasculature development 6.839479e-4
GO:0044154 histone H3-K14 acetylation 7.039473e-4
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway 7.310352e-4
GO:0010718 positive regulation of epithelial to mesenchymal transition 7.374390e-4
GO:0046512 sphingosine biosynthetic process 7.454277e-4
GO:2000210 positive regulation of anoikis 7.614568e-4
GO:0072089 stem cell proliferation 7.614568e-4
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 7.661665e-4
GO:0048703 embryonic viscerocranium morphogenesis 7.669857e-4
GO:0034766 negative regulation of ion transmembrane transport 7.674046e-4
GO:0042538 hyperosmotic salinity response 7.674241e-4
GO:0007621 negative regulation of female receptivity 7.674241e-4
GO:0014013 regulation of gliogenesis 7.774334e-4
GO:0030449 regulation of complement activation 7.788998e-4
GO:0050765 negative regulation of phagocytosis 7.910245e-4
GO:0014020 primary neural tube formation 8.091173e-4
GO:0035105 sterol regulatory element binding protein import into nucleus 8.092506e-4
GO:0032425 positive regulation of mismatch repair 8.092506e-4
GO:0050766 positive regulation of phagocytosis 8.242057e-4
GO:0051588 regulation of neurotransmitter transport 8.359510e-4
GO:0032928 regulation of superoxide anion generation 8.474692e-4
GO:0060606 tube closure 8.652621e-4
GO:0070489 T cell aggregation 8.760459e-4
GO:0031329 regulation of cellular catabolic process 8.889266e-4
GO:0055082 cellular chemical homeostasis 8.941947e-4
GO:0048568 embryonic organ development 9.132523e-4
GO:0050729 positive regulation of inflammatory response 9.184428e-4
GO:0007431 salivary gland development 9.372641e-4
GO:0072104 glomerular capillary formation 9.448152e-4
GO:0006268 DNA unwinding involved in replication 9.448152e-4
GO:0051932 synaptic transmission, GABAergic 9.576429e-4
GO:0032074 negative regulation of nuclease activity 9.576429e-4
GO:0060249 anatomical structure homeostasis 9.797063e-4
GO:0006670 sphingosine metabolic process 1.000651e-3
GO:0035507 regulation of myosin-light-chain-phosphatase activity 1.006179e-3
GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity 1.022564e-3
GO:0003062 regulation of heart rate by chemical signal 1.022564e-3
GO:0031063 regulation of histone deacetylation 1.057519e-3
GO:2000438 negative regulation of monocyte extravasation 1.068205e-3
GO:0080154 regulation of fertilization 1.068205e-3
GO:0035723 interleukin-15-mediated signaling pathway 1.068205e-3
GO:0035724 CD24 biosynthetic process 1.068205e-3
GO:0031915 positive regulation of synaptic plasticity 1.069658e-3
GO:0071731 response to nitric oxide 1.078559e-3
GO:0043966 histone H3 acetylation 1.094864e-3
GO:0035136 forelimb morphogenesis 1.094864e-3
GO:0015816 glycine transport 1.104537e-3
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1.107593e-3
GO:0046426 negative regulation of JAK-STAT cascade 1.130820e-3
GO:0010172 embryonic body morphogenesis 1.139069e-3
GO:0032909 regulation of transforming growth factor beta2 production 1.167589e-3
GO:0032792 negative regulation of CREB transcription factor activity 1.168537e-3
GO:0072234 metanephric nephron tubule development 1.180482e-3
GO:0072488 ammonium transmembrane transport 1.185812e-3
GO:0042634 regulation of hair cycle 1.186742e-3
GO:0048010 vascular endothelial growth factor receptor signaling pathway 1.196978e-3
GO:0007128 meiotic prophase I 1.208296e-3
GO:0007626 locomotory behavior 1.210647e-3
GO:0030952 establishment or maintenance of cytoskeleton polarity 1.211357e-3
GO:0006012 galactose metabolic process 1.224486e-3
GO:0030902 hindbrain development 1.240109e-3
GO:0030166 proteoglycan biosynthetic process 1.240409e-3
GO:0043547 positive regulation of GTPase activity 1.248736e-3
GO:0051532 regulation of NFAT protein import into nucleus 1.287364e-3
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 1.291738e-3
GO:0035854 eosinophil fate commitment 1.297869e-3
GO:0030222 eosinophil differentiation 1.297869e-3
GO:0072355 histone H3-T3 phosphorylation 1.311598e-3
GO:0042780 tRNA 3'-end processing 1.311598e-3
GO:0070141 response to UV-A 1.331349e-3
GO:0032864 activation of Cdc42 GTPase activity 1.333874e-3
GO:0019087 transformation of host cell by virus 1.342194e-3
GO:0045085 negative regulation of interleukin-2 biosynthetic process 1.348336e-3
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 1.373946e-3
GO:0048592 eye morphogenesis 1.378026e-3
GO:0048385 regulation of retinoic acid receptor signaling pathway 1.443806e-3
GO:0007402 ganglion mother cell fate determination 1.464831e-3
GO:0006657 CDP-choline pathway 1.476406e-3
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 1.516215e-3
GO:0040020 regulation of meiosis 1.552238e-3
GO:0008366 axon ensheathment 1.567070e-3
GO:0048593 camera-type eye morphogenesis 1.573171e-3
GO:0046588 negative regulation of calcium-dependent cell-cell adhesion 1.623105e-3
GO:0051890 regulation of cardioblast differentiation 1.629375e-3
GO:0050773 regulation of dendrite development 1.636743e-3
GO:0051005 negative regulation of lipoprotein lipase activity 1.636867e-3
GO:2000346 negative regulation of hepatocyte proliferation 1.702271e-3
GO:2000639 negative regulation of SREBP-mediated signaling pathway 1.702271e-3
GO:0046208 spermine catabolic process 1.706033e-3
GO:0043117 positive regulation of vascular permeability 1.740462e-3
GO:0090031 positive regulation of steroid hormone biosynthetic process 1.743659e-3
GO:0072054 renal outer medulla development 1.760115e-3
GO:0072053 renal inner medulla development 1.760115e-3
GO:0045143 homologous chromosome segregation 1.763469e-3
GO:0007156 homophilic cell adhesion 1.771981e-3
GO:0045116 protein neddylation 1.792393e-3
GO:0060896 neural plate pattern specification 1.799626e-3
GO:0060710 chorio-allantoic fusion 1.814576e-3
GO:0060221 retinal rod cell differentiation 1.818505e-3
GO:0070255 regulation of mucus secretion 1.818505e-3
GO:0043932 ossification involved in bone remodeling 1.875720e-3
GO:0009792 embryo development ending in birth or egg hatching 1.898923e-3
GO:2000744 positive regulation of anterior head development 1.912019e-3
GO:0060018 astrocyte fate commitment 1.945914e-3
GO:0045807 positive regulation of endocytosis 1.989434e-3
GO:0010954 positive regulation of protein processing 1.989866e-3
GO:0046520 sphingoid biosynthetic process 1.996238e-3
GO:0002502 peptide antigen assembly with MHC class I protein complex 2.011284e-3
GO:0072080 nephron tubule development 2.051187e-3
GO:0050886 endocrine process 2.099449e-3
GO:0002637 regulation of immunoglobulin production 2.103424e-3
GO:0043009 chordate embryonic development 2.108952e-3
GO:0071453 cellular response to oxygen levels 2.111495e-3
GO:0072170 metanephric tubule development 2.116843e-3
GO:0006706 steroid catabolic process 2.120281e-3
GO:0045924 regulation of female receptivity 2.150978e-3
GO:0090199 regulation of release of cytochrome c from mitochondria 2.194894e-3
GO:0072181 mesonephric duct formation 2.208000e-3
GO:0070672 response to interleukin-15 2.215097e-3
GO:0021569 rhombomere 3 development 2.215097e-3
GO:0060215 primitive hemopoiesis 2.248271e-3
GO:0060976 coronary vasculature development 2.253561e-3
GO:0010889 regulation of sequestering of triglyceride 2.253561e-3
GO:0007389 pattern specification process 2.255641e-3
GO:0000726 non-recombinational repair 2.272007e-3
GO:0060973 cell migration involved in heart development 2.275577e-3
GO:0003218 cardiac left ventricle formation 2.321920e-3
GO:0021533 cell differentiation in hindbrain 2.331371e-3
GO:0044334 canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition 2.343206e-3
GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process 2.343206e-3
GO:0030277 maintenance of gastrointestinal epithelium 2.368286e-3
GO:0048702 embryonic neurocranium morphogenesis 2.380856e-3
GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure 2.395682e-3
GO:0030037 actin filament reorganization involved in cell cycle 2.397247e-3
GO:0016064 immunoglobulin mediated immune response 2.406660e-3
GO:0033120 positive regulation of RNA splicing 2.419741e-3
GO:0060040 retinal bipolar neuron differentiation 2.422793e-3
GO:0031065 positive regulation of histone deacetylation 2.438545e-3
GO:0048745 smooth muscle tissue development 2.463698e-3
GO:0071593 lymphocyte aggregation 2.475070e-3
GO:0033057 multicellular organismal reproductive behavior 2.502396e-3
GO:0045663 positive regulation of myoblast differentiation 2.507656e-3
GO:0060350 endochondral bone morphogenesis 2.584633e-3
GO:0048634 regulation of muscle organ development 2.594532e-3
GO:0060980 cell migration involved in coronary vasculogenesis 2.632187e-3
GO:0070555 response to interleukin-1 2.641871e-3
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 2.689981e-3
GO:0045637 regulation of myeloid cell differentiation 2.703271e-3
GO:0021797 forebrain anterior/posterior pattern specification 2.706935e-3
GO:0001666 response to hypoxia 2.744549e-3
GO:0019725 cellular homeostasis 2.756611e-3
GO:0060133 somatotropin secreting cell development 2.765426e-3
GO:0001974 blood vessel remodeling 2.779751e-3
GO:0031099 regeneration 2.796024e-3
GO:0016075 rRNA catabolic process 2.823139e-3
GO:0060047 heart contraction 2.898128e-3
GO:0061046 regulation of branching involved in lung morphogenesis 2.916134e-3
GO:0035295 tube development 2.920707e-3
GO:0019233 sensory perception of pain 3.034451e-3
GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development 3.038199e-3
GO:0031022 nuclear migration along microfilament 3.084800e-3
GO:0018208 peptidyl-proline modification 3.095386e-3
GO:0045657 positive regulation of monocyte differentiation 3.106126e-3
GO:0002076 osteoblast development 3.115976e-3
GO:0021702 cerebellar Purkinje cell differentiation 3.143067e-3
GO:0030823 regulation of cGMP metabolic process 3.194309e-3
GO:0090193 positive regulation of glomerulus development 3.225540e-3
GO:0021547 midbrain-hindbrain boundary initiation 3.241125e-3
GO:0021501 prechordal plate formation 3.241125e-3
GO:0042297 vocal learning 3.260443e-3
GO:0034227 tRNA thio-modification 3.260443e-3
GO:0002098 tRNA wobble uridine modification 3.260443e-3
GO:0043010 camera-type eye development 3.267359e-3
GO:0060466 activation of meiosis involved in egg activation 3.279545e-3
GO:0044130 negative regulation of growth of symbiont in host 3.300626e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0030488 tRNA methylation 1.121286e-15
GO:0010565 regulation of cellular ketone metabolic process 2.354649e-12
GO:0042304 regulation of fatty acid biosynthetic process 1.467479e-11
GO:0051049 regulation of transport 1.526393e-11
GO:0043269 regulation of ion transport 8.563847e-10
GO:0009895 negative regulation of catabolic process 1.732906e-9
GO:0060341 regulation of cellular localization 3.118345e-9
GO:0070588 calcium ion transmembrane transport 3.154181e-9
GO:0072595 maintenance of protein localization to organelle 3.452567e-9
GO:0019217 regulation of fatty acid metabolic process 5.347112e-9
GO:0033238 regulation of cellular amine metabolic process 6.807600e-9
GO:0031330 negative regulation of cellular catabolic process 8.904047e-9
GO:0050995 negative regulation of lipid catabolic process 9.322636e-9
GO:0006081 cellular aldehyde metabolic process 1.016406e-8
GO:0003008 system process 1.242722e-8
GO:0033700 phospholipid efflux 1.258294e-8
GO:0032369 negative regulation of lipid transport 1.490925e-8
GO:0006400 tRNA modification 1.532504e-8
GO:0046092 deoxycytidine metabolic process 1.570220e-8
GO:0034762 regulation of transmembrane transport 1.768362e-8
GO:0050994 regulation of lipid catabolic process 1.976295e-8
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 2.585118e-8
GO:0034382 chylomicron remnant clearance 3.751707e-8
GO:0051457 maintenance of protein location in nucleus 4.064424e-8
GO:0010985 negative regulation of lipoprotein particle clearance 4.840275e-8
GO:0032368 regulation of lipid transport 5.184579e-8
GO:0045723 positive regulation of fatty acid biosynthetic process 5.628950e-8
GO:0001510 RNA methylation 5.669007e-8
GO:0051924 regulation of calcium ion transport 6.414978e-8
GO:0007586 digestion 1.252322e-7
GO:0045923 positive regulation of fatty acid metabolic process 1.928747e-7
GO:0008033 tRNA processing 2.085625e-7
GO:0010984 regulation of lipoprotein particle clearance 2.304442e-7
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 2.422321e-7
GO:0071529 cementum mineralization 3.392142e-7
GO:0046184 aldehyde biosynthetic process 3.442618e-7
GO:0034765 regulation of ion transmembrane transport 3.564012e-7
GO:0051046 regulation of secretion 3.819695e-7
GO:0006942 regulation of striated muscle contraction 4.839396e-7
GO:0051047 positive regulation of secretion 4.844764e-7
GO:0009185 ribonucleoside diphosphate metabolic process 6.729437e-7
GO:0046501 protoporphyrinogen IX metabolic process 1.019947e-6
GO:0043932 ossification involved in bone remodeling 1.032255e-6
GO:0010522 regulation of calcium ion transport into cytosol 1.312481e-6
GO:0032502 developmental process 1.581503e-6
GO:0016074 snoRNA metabolic process 1.584135e-6
GO:0010936 negative regulation of macrophage cytokine production 1.686904e-6
GO:0010959 regulation of metal ion transport 1.696245e-6
GO:0045922 negative regulation of fatty acid metabolic process 1.714262e-6
GO:0023052 signaling 1.723258e-6
GO:0071456 cellular response to hypoxia 1.838332e-6
GO:0030819 positive regulation of cAMP biosynthetic process 1.947923e-6
GO:0035249 synaptic transmission, glutamatergic 2.159352e-6
GO:0015780 nucleotide-sugar transport 2.277635e-6
GO:0002407 dendritic cell chemotaxis 2.439502e-6
GO:0030801 positive regulation of cyclic nucleotide metabolic process 2.457890e-6
GO:0055117 regulation of cardiac muscle contraction 2.685103e-6
GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity 2.884202e-6
GO:0009132 nucleoside diphosphate metabolic process 3.036715e-6
GO:0033002 muscle cell proliferation 3.115856e-6
GO:0007154 cell communication 3.257471e-6
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 3.681422e-6
GO:0018022 peptidyl-lysine methylation 3.681422e-6
GO:0009125 nucleoside monophosphate catabolic process 3.746112e-6
GO:0032375 negative regulation of cholesterol transport 4.103754e-6
GO:0018192 enzyme active site formation via L-cysteine persulfide 4.226701e-6
GO:0006117 acetaldehyde metabolic process 4.272019e-6
GO:0021670 lateral ventricle development 4.469951e-6
GO:0060338 regulation of type I interferon-mediated signaling pathway 4.484745e-6
GO:2000021 regulation of ion homeostasis 4.561393e-6
GO:0050789 regulation of biological process 4.919442e-6
GO:0065005 protein-lipid complex assembly 5.291356e-6
GO:0046939 nucleotide phosphorylation 5.453145e-6
GO:0045806 negative regulation of endocytosis 5.718461e-6
GO:0010676 positive regulation of cellular carbohydrate metabolic process 5.960170e-6
GO:0046889 positive regulation of lipid biosynthetic process 5.988925e-6
GO:0045576 mast cell activation 6.057388e-6
GO:0030855 epithelial cell differentiation 6.156476e-6
GO:0032501 multicellular organismal process 6.179843e-6
GO:0031000 response to caffeine 6.443586e-6
GO:0043279 response to alkaloid 6.453786e-6
GO:0051279 regulation of release of sequestered calcium ion into cytosol 6.482442e-6
GO:0071248 cellular response to metal ion 6.574626e-6
GO:0051005 negative regulation of lipoprotein lipase activity 6.743154e-6
GO:0010907 positive regulation of glucose metabolic process 6.966010e-6
GO:0045834 positive regulation of lipid metabolic process 7.848993e-6
GO:0032374 regulation of cholesterol transport 7.910516e-6
GO:0032891 negative regulation of organic acid transport 8.688812e-6
GO:0021591 ventricular system development 8.715943e-6
GO:0031536 positive regulation of exit from mitosis 8.858496e-6
GO:0070482 response to oxygen levels 8.893943e-6
GO:0060696 regulation of phospholipid catabolic process 9.185924e-6
GO:0010452 histone H3-K36 methylation 9.847502e-6
GO:0010900 negative regulation of phosphatidylcholine catabolic process 9.889531e-6
GO:0045598 regulation of fat cell differentiation 1.044527e-5
GO:0045717 negative regulation of fatty acid biosynthetic process 1.076068e-5
GO:0030804 positive regulation of cyclic nucleotide biosynthetic process 1.170012e-5
GO:0071453 cellular response to oxygen levels 1.186469e-5
GO:0050708 regulation of protein secretion 1.270920e-5
GO:0034220 ion transmembrane transport 1.461678e-5
GO:0044057 regulation of system process 1.473890e-5
GO:0032409 regulation of transporter activity 1.534587e-5
GO:0009134 nucleoside diphosphate catabolic process 1.574179e-5
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 1.722961e-5
GO:0032655 regulation of interleukin-12 production 1.818106e-5
GO:0007270 neuron-neuron synaptic transmission 1.850160e-5
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 1.883653e-5
GO:0042559 pteridine-containing compound biosynthetic process 1.909502e-5
GO:0051901 positive regulation of mitochondrial depolarization 2.003001e-5
GO:0003254 regulation of membrane depolarization 2.013707e-5
GO:0010987 negative regulation of high-density lipoprotein particle clearance 2.130392e-5
GO:0010897 negative regulation of triglyceride catabolic process 2.130392e-5
GO:0030300 regulation of intestinal cholesterol absorption 2.156723e-5
GO:0031326 regulation of cellular biosynthetic process 2.228238e-5
GO:0065007 biological regulation 2.310196e-5
GO:0045055 regulated secretory pathway 2.313997e-5
GO:0080090 regulation of primary metabolic process 2.324563e-5
GO:0007613 memory 2.361270e-5
GO:0009817 defense response to fungus, incompatible interaction 2.424610e-5
GO:0009214 cyclic nucleotide catabolic process 2.537600e-5
GO:0032412 regulation of ion transmembrane transporter activity 2.542665e-5
GO:0031327 negative regulation of cellular biosynthetic process 2.590337e-5
GO:0051239 regulation of multicellular organismal process 2.634587e-5
GO:0009191 ribonucleoside diphosphate catabolic process 2.643993e-5
GO:0071496 cellular response to external stimulus 2.709658e-5
GO:0009636 response to toxin 2.718820e-5
GO:0050880 regulation of blood vessel size 2.737332e-5
GO:0032879 regulation of localization 2.765462e-5
GO:0055085 transmembrane transport 3.018142e-5
GO:0006376 mRNA splice site selection 3.021456e-5
GO:0003018 vascular process in circulatory system 3.029545e-5
GO:0035150 regulation of tube size 3.045574e-5
GO:0016579 protein deubiquitination 3.047339e-5
GO:0001666 response to hypoxia 3.147596e-5
GO:0042249 establishment of planar polarity of embryonic epithelium 3.227112e-5
GO:0042311 vasodilation 3.353087e-5
GO:0051764 actin crosslink formation 3.372397e-5
GO:0009890 negative regulation of biosynthetic process 3.392577e-5
GO:0048731 system development 3.413041e-5
GO:0006779 porphyrin-containing compound biosynthetic process 3.469427e-5
GO:0055017 cardiac muscle tissue growth 3.487384e-5
GO:0006399 tRNA metabolic process 3.703058e-5
GO:0046330 positive regulation of JNK cascade 3.706758e-5
GO:0042177 negative regulation of protein catabolic process 3.715275e-5
GO:0048261 negative regulation of receptor-mediated endocytosis 3.751957e-5
GO:0009892 negative regulation of metabolic process 3.803331e-5
GO:0051099 positive regulation of binding 3.987385e-5
GO:0050794 regulation of cellular process 4.002530e-5
GO:0019438 aromatic compound biosynthetic process 4.230415e-5
GO:0014034 neural crest cell fate commitment 4.552845e-5
GO:0060079 regulation of excitatory postsynaptic membrane potential 4.559019e-5
GO:0015862 uridine transport 4.586718e-5
GO:0001832 blastocyst growth 4.642790e-5
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 4.806715e-5
GO:0044241 lipid digestion 4.820167e-5
GO:0017157 regulation of exocytosis 4.924624e-5
GO:0043691 reverse cholesterol transport 5.037223e-5
GO:0032488 Cdc42 protein signal transduction 5.273483e-5
GO:0009396 folic acid-containing compound biosynthetic process 5.381556e-5
GO:0001539 ciliary or flagellar motility 5.546511e-5
GO:0043587 tongue morphogenesis 5.739499e-5
GO:0002739 regulation of cytokine secretion involved in immune response 5.739499e-5
GO:0006109 regulation of carbohydrate metabolic process 5.787410e-5
GO:0031323 regulation of cellular metabolic process 5.794404e-5
GO:0060627 regulation of vesicle-mediated transport 5.873155e-5
GO:0050714 positive regulation of protein secretion 5.877954e-5
GO:0035725 sodium ion transmembrane transport 5.903171e-5
GO:0007275 multicellular organismal development 5.908620e-5
GO:0046890 regulation of lipid biosynthetic process 5.991017e-5
GO:0007165 signal transduction 6.079425e-5
GO:0010989 negative regulation of low-density lipoprotein particle clearance 6.079430e-5
GO:0035887 aortic smooth muscle cell differentiation 6.079430e-5
GO:0014074 response to purine-containing compound 6.203745e-5
GO:0015864 pyrimidine nucleoside transport 6.315947e-5
GO:0050916 sensory perception of sweet taste 6.660725e-5
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 6.784859e-5
GO:0010873 positive regulation of cholesterol esterification 6.826219e-5
GO:0072531 pyrimidine-containing compound transmembrane transport 7.000712e-5
GO:0043303 mast cell degranulation 7.006319e-5
GO:0010675 regulation of cellular carbohydrate metabolic process 7.550870e-5
GO:0009451 RNA modification 7.559826e-5
GO:0032965 regulation of collagen biosynthetic process 7.571374e-5
GO:0033013 tetrapyrrole metabolic process 7.640130e-5
GO:0009889 regulation of biosynthetic process 7.756759e-5
GO:0043653 mitochondrial fragmentation involved in apoptosis 7.813213e-5
GO:0010982 regulation of high-density lipoprotein particle clearance 7.824738e-5
GO:0008156 negative regulation of DNA replication 7.869582e-5
GO:0046031 ADP metabolic process 7.908986e-5
GO:0022898 regulation of transmembrane transporter activity 8.349471e-5
GO:0048026 positive regulation of nuclear mRNA splicing, via spliceosome 8.837393e-5
GO:0045722 positive regulation of gluconeogenesis 8.837393e-5
GO:0002718 regulation of cytokine production involved in immune response 8.863535e-5
GO:0006778 porphyrin-containing compound metabolic process 8.909393e-5
GO:0043299 leukocyte degranulation 9.325870e-5
GO:0071169 establishment of protein localization to chromatin 9.347612e-5
GO:0035865 cellular response to potassium ion 9.347612e-5
GO:0019047 provirus integration 9.347612e-5
GO:0034651 cortisol biosynthetic process 9.347612e-5
GO:0045601 regulation of endothelial cell differentiation 9.492020e-5
GO:0051988 regulation of attachment of spindle microtubules to kinetochore 9.592615e-5
GO:0044240 multicellular organismal lipid catabolic process 9.909567e-5
GO:2000300 regulation of synaptic vesicle exocytosis 1.006385e-4
GO:0031328 positive regulation of cellular biosynthetic process 1.006442e-4
GO:0009891 positive regulation of biosynthetic process 1.056861e-4
GO:0051171 regulation of nitrogen compound metabolic process 1.061796e-4
GO:0045074 regulation of interleukin-10 biosynthetic process 1.067885e-4
GO:0007610 behavior 1.091992e-4
GO:0007422 peripheral nervous system development 1.108849e-4
GO:0090257 regulation of muscle system process 1.136719e-4
GO:0051051 negative regulation of transport 1.145560e-4
GO:0015824 proline transport 1.145755e-4
GO:0035524 proline transmembrane transport 1.150351e-4
GO:0046341 CDP-diacylglycerol metabolic process 1.164789e-4
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 1.164789e-4
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 1.164789e-4
GO:0015684 ferrous iron transport 1.186406e-4
GO:0070201 regulation of establishment of protein localization 1.203223e-4
GO:0019722 calcium-mediated signaling 1.234283e-4
GO:0010906 regulation of glucose metabolic process 1.237986e-4
GO:0070328 triglyceride homeostasis 1.254644e-4
GO:0009894 regulation of catabolic process 1.291043e-4
GO:0071407 cellular response to organic cyclic compound 1.297252e-4
GO:0006739 NADP metabolic process 1.317983e-4
GO:0014037 Schwann cell differentiation 1.319944e-4
GO:0048856 anatomical structure development 1.327895e-4
GO:0030799 regulation of cyclic nucleotide metabolic process 1.372367e-4
GO:0018026 peptidyl-lysine monomethylation 1.375831e-4
GO:0043414 macromolecule methylation 1.428738e-4
GO:0032967 positive regulation of collagen biosynthetic process 1.437296e-4
GO:0031324 negative regulation of cellular metabolic process 1.466934e-4
GO:2000191 regulation of fatty acid transport 1.481121e-4
GO:0043255 regulation of carbohydrate biosynthetic process 1.481834e-4
GO:0002274 myeloid leukocyte activation 1.505424e-4
GO:0060419 heart growth 1.535564e-4
GO:0014070 response to organic cyclic compound 1.565916e-4
GO:0070483 detection of hypoxia 1.643555e-4
GO:0010633 negative regulation of epithelial cell migration 1.687072e-4
GO:0002444 myeloid leukocyte mediated immunity 1.721929e-4
GO:0021592 fourth ventricle development 1.755546e-4
GO:0030154 cell differentiation 1.764730e-4
GO:0045940 positive regulation of steroid metabolic process 1.768755e-4
GO:0042255 ribosome assembly 1.793762e-4
GO:0046186 acetaldehyde biosynthetic process 1.887272e-4
GO:0044342 type B pancreatic cell proliferation 1.887272e-4
GO:0055015 ventricular cardiac muscle cell development 1.924637e-4
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.937677e-4
GO:0001817 regulation of cytokine production 1.949918e-4
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 1.952036e-4
GO:0031329 regulation of cellular catabolic process 1.975099e-4
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 2.010657e-4
GO:0060334 regulation of interferon-gamma-mediated signaling pathway 2.046535e-4
GO:0048869 cellular developmental process 2.060724e-4
GO:0031914 negative regulation of synaptic plasticity 2.090721e-4
GO:0003032 detection of oxygen 2.107990e-4
GO:0014051 gamma-aminobutyric acid secretion 2.126970e-4
GO:0046373 L-arabinose metabolic process 2.193030e-4
GO:0000238 zygotene 2.193030e-4
GO:0010721 negative regulation of cell development 2.224029e-4
GO:0010872 regulation of cholesterol esterification 2.259334e-4
GO:0045082 positive regulation of interleukin-10 biosynthetic process 2.271044e-4
GO:0007096 regulation of exit from mitosis 2.271044e-4
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 2.279691e-4
GO:0007611 learning or memory 2.286234e-4
GO:0060347 heart trabecula formation 2.315182e-4
GO:0016539 intein-mediated protein splicing 2.341651e-4
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 2.388699e-4
GO:0032933 SREBP-mediated signaling pathway 2.487331e-4
GO:0002740 negative regulation of cytokine secretion involved in immune response 2.487331e-4
GO:0042482 positive regulation of odontogenesis 2.521882e-4
GO:0045906 negative regulation of vasoconstriction 2.544888e-4
GO:0033344 cholesterol efflux 2.587577e-4
GO:0003012 muscle system process 2.589037e-4
GO:0071773 cellular response to BMP stimulus 2.627352e-4
GO:0060620 regulation of cholesterol import 2.627352e-4
GO:0040007 growth 2.807709e-4
GO:0044058 regulation of digestive system process 2.959688e-4
GO:0002507 tolerance induction 2.969141e-4
GO:0070646 protein modification by small protein removal 3.111402e-4
GO:0017085 response to insecticide 3.161279e-4
GO:0061001 regulation of dendritic spine morphogenesis 3.200465e-4
GO:0019219 regulation of nucleobase-containing compound metabolic process 3.210673e-4
GO:0006241 CTP biosynthetic process 3.215499e-4
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 3.302094e-4
GO:0051930 regulation of sensory perception of pain 3.312582e-4
GO:0006959 humoral immune response 3.416625e-4
GO:0001833 inner cell mass cell proliferation 3.419136e-4
GO:0003229 ventricular cardiac muscle tissue development 3.461405e-4
GO:0046293 formaldehyde biosynthetic process 3.518406e-4
GO:0007202 activation of phospholipase C activity 3.529026e-4
GO:0033136 serine phosphorylation of STAT3 protein 3.550341e-4
GO:0042035 regulation of cytokine biosynthetic process 3.558502e-4
GO:0001649 osteoblast differentiation 3.562098e-4
GO:0010595 positive regulation of endothelial cell migration 3.637269e-4
GO:0003009 skeletal muscle contraction 3.718384e-4
GO:0033363 secretory granule organization 3.721488e-4
GO:0033205 cell cycle cytokinesis 3.784178e-4
GO:0042755 eating behavior 3.789607e-4
GO:0010896 regulation of triglyceride catabolic process 3.806858e-4
GO:0061337 cardiac conduction 3.814269e-4
GO:0060038 cardiac muscle cell proliferation 3.814269e-4
GO:0000045 autophagic vacuole assembly 3.833869e-4
GO:0070584 mitochondrion morphogenesis 3.860418e-4
GO:0045833 negative regulation of lipid metabolic process 3.867080e-4
GO:0006937 regulation of muscle contraction 3.883893e-4
GO:0034101 erythrocyte homeostasis 4.002665e-4
GO:0030814 regulation of cAMP metabolic process 4.006584e-4
GO:0010863 positive regulation of phospholipase C activity 4.034051e-4
GO:0010605 negative regulation of macromolecule metabolic process 4.059706e-4
GO:0010629 negative regulation of gene expression 4.068277e-4
GO:0006198 cAMP catabolic process 4.068835e-4
GO:0031644 regulation of neurological system process 4.133001e-4
GO:0030817 regulation of cAMP biosynthetic process 4.236764e-4
GO:0071241 cellular response to inorganic substance 4.332910e-4
GO:0030431 sleep 4.357944e-4
GO:0032099 negative regulation of appetite 4.424476e-4
GO:0060621 negative regulation of cholesterol import 4.477829e-4
GO:0010558 negative regulation of macromolecule biosynthetic process 4.499304e-4
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 4.499310e-4
GO:0060192 negative regulation of lipase activity 4.633649e-4
GO:0045600 positive regulation of fat cell differentiation 4.723592e-4
GO:0008286 insulin receptor signaling pathway 4.864410e-4
GO:0050890 cognition 4.965400e-4
GO:0009201 ribonucleoside triphosphate biosynthetic process 5.013184e-4
GO:0045368 positive regulation of interleukin-13 biosynthetic process 5.037742e-4
GO:0006982 response to lipid hydroperoxide 5.037742e-4
GO:0070875 positive regulation of glycogen metabolic process 5.047990e-4
GO:0034699 response to luteinizing hormone stimulus 5.076694e-4
GO:0006782 protoporphyrinogen IX biosynthetic process 5.076694e-4
GO:0042558 pteridine-containing compound metabolic process 5.123050e-4
GO:0035235 ionotropic glutamate receptor signaling pathway 5.126984e-4
GO:0065009 regulation of molecular function 5.292367e-4
GO:0060078 regulation of postsynaptic membrane potential 5.391094e-4
GO:0043687 post-translational protein modification 5.411717e-4
GO:0034695 response to prostaglandin E stimulus 5.411717e-4
GO:0070169 positive regulation of biomineral tissue development 5.442571e-4
GO:0009142 nucleoside triphosphate biosynthetic process 5.557725e-4
GO:0048343 paraxial mesodermal cell fate commitment 5.594953e-4
GO:0000245 spliceosome assembly 5.610641e-4
GO:0048143 astrocyte activation 5.660134e-4
GO:0060193 positive regulation of lipase activity 5.664806e-4
GO:0008615 pyridoxine biosynthetic process 5.837280e-4
GO:0006930 substrate-dependent cell migration, cell extension 5.837280e-4
GO:0060281 regulation of oocyte development 5.852076e-4
GO:0060282 positive regulation of oocyte development 5.852076e-4
GO:0048167 regulation of synaptic plasticity 5.923046e-4
GO:0032096 negative regulation of response to food 6.018095e-4
GO:0051533 positive regulation of NFAT protein import into nucleus 6.050864e-4
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 6.183262e-4
GO:0044246 regulation of multicellular organismal metabolic process 6.196546e-4
GO:0030802 regulation of cyclic nucleotide biosynthetic process 6.306209e-4
GO:0051223 regulation of protein transport 6.512814e-4
GO:0034633 retinol transport 6.528227e-4
GO:0071622 regulation of granulocyte chemotaxis 6.552894e-4
GO:0033239 negative regulation of cellular amine metabolic process 6.558015e-4
GO:0021678 third ventricle development 6.578542e-4
GO:0050713 negative regulation of interleukin-1 beta secretion 6.578542e-4
GO:0051172 negative regulation of nitrogen compound metabolic process 6.596487e-4
GO:0050877 neurological system process 6.651607e-4
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 6.669871e-4
GO:0051241 negative regulation of multicellular organismal process 6.728547e-4
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 6.739763e-4
GO:0051489 regulation of filopodium assembly 6.740589e-4
GO:0006816 calcium ion transport 6.817237e-4
GO:0051403 stress-activated MAPK cascade 6.998185e-4
GO:0051586 positive regulation of dopamine uptake 7.050966e-4
GO:0019682 glyceraldehyde-3-phosphate metabolic process 7.050966e-4
GO:0006936 muscle contraction 7.211634e-4
GO:0051900 regulation of mitochondrial depolarization 7.224242e-4
GO:0007184 SMAD protein import into nucleus 7.260640e-4
GO:0007517 muscle organ development 7.274290e-4
GO:0048259 regulation of receptor-mediated endocytosis 7.401228e-4
GO:0070838 divalent metal ion transport 7.590951e-4
GO:0055010 ventricular cardiac muscle tissue morphogenesis 7.679293e-4
GO:0050849 negative regulation of calcium-mediated signaling 7.877603e-4
GO:0048659 smooth muscle cell proliferation 7.882282e-4
GO:0090037 positive regulation of protein kinase C signaling cascade 7.918441e-4
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 8.095466e-4
GO:0044093 positive regulation of molecular function 8.246572e-4
GO:0016126 sterol biosynthetic process 8.334574e-4
GO:0052200 response to host defenses 8.386646e-4
GO:0031668 cellular response to extracellular stimulus 8.431973e-4
GO:0002675 positive regulation of acute inflammatory response 8.675686e-4
GO:0015804 neutral amino acid transport 8.709052e-4
GO:0014916 regulation of lung blood pressure 8.731393e-4
GO:0006695 cholesterol biosynthetic process 8.758097e-4
GO:0007181 transforming growth factor beta receptor complex assembly 8.821219e-4
GO:0090086 negative regulation of protein deubiquitination 8.821219e-4
GO:0003094 glomerular filtration 8.821219e-4
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 8.952431e-4
GO:0034504 protein localization to nucleus 9.121993e-4
GO:0090209 negative regulation of triglyceride metabolic process 9.204542e-4
GO:0033240 positive regulation of cellular amine metabolic process 9.204542e-4
GO:0060491 regulation of cell projection assembly 9.427402e-4
GO:0003013 circulatory system process 9.465611e-4
GO:0034377 plasma lipoprotein particle assembly 9.560150e-4
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 9.560150e-4
GO:0050804 regulation of synaptic transmission 9.979755e-4
GO:0060998 regulation of dendritic spine development 1.000978e-3
GO:0018023 peptidyl-lysine trimethylation 1.014958e-3
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 1.034423e-3
GO:0006098 pentose-phosphate shunt 1.044197e-3
GO:0009145 purine nucleoside triphosphate biosynthetic process 1.066457e-3
GO:0046321 positive regulation of fatty acid oxidation 1.069976e-3
GO:0031998 regulation of fatty acid beta-oxidation 1.089804e-3
GO:0072511 divalent inorganic cation transport 1.090501e-3
GO:0006481 C-terminal protein methylation 1.092397e-3
GO:0035269 protein O-linked mannosylation 1.092397e-3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 1.107426e-3
GO:0006704 glucocorticoid biosynthetic process 1.107721e-3
GO:0048518 positive regulation of biological process 1.110682e-3
GO:0060124 positive regulation of growth hormone secretion 1.124320e-3
GO:2000377 regulation of reactive oxygen species metabolic process 1.132417e-3
GO:0051098 regulation of binding 1.137982e-3
GO:0007399 nervous system development 1.175193e-3
GO:0009893 positive regulation of metabolic process 1.196715e-3
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.200864e-3
GO:0007386 compartment pattern specification 1.238633e-3
GO:0018027 peptidyl-lysine dimethylation 1.238668e-3
GO:2000703 negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation 1.267255e-3
GO:2000734 negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation 1.267255e-3
GO:2000664 positive regulation of interleukin-5 secretion 1.267255e-3
GO:2000667 positive regulation of interleukin-13 secretion 1.267255e-3
GO:0001806 type IV hypersensitivity 1.267255e-3
GO:0060374 mast cell differentiation 1.267255e-3
GO:2000607 negative regulation of cell proliferation involved in mesonephros development 1.267255e-3
GO:0044253 positive regulation of multicellular organismal metabolic process 1.276719e-3
GO:0072220 metanephric descending thin limb development 1.324283e-3
GO:0072230 metanephric proximal straight tubule development 1.324283e-3
GO:0072232 metanephric proximal convoluted tubule segment 2 development 1.324283e-3
GO:0051458 corticotropin secretion 1.324283e-3
GO:0085018 maintenance of symbiont-containing vacuole via substance secreted by host 1.324283e-3
GO:0035378 carbon dioxide transmembrane transport 1.324283e-3
GO:0033617 mitochondrial respiratory chain complex IV assembly 1.324283e-3
GO:0016142 O-glycoside catabolic process 1.324283e-3
GO:0035377 transepithelial water transport 1.324283e-3
GO:0034447 very-low-density lipoprotein particle clearance 1.342144e-3
GO:0044030 regulation of DNA methylation 1.355324e-3
GO:0043113 receptor clustering 1.364062e-3
GO:0045603 positive regulation of endothelial cell differentiation 1.372387e-3
GO:0048644 muscle organ morphogenesis 1.383922e-3
GO:0071277 cellular response to calcium ion 1.412236e-3
GO:0050709 negative regulation of protein secretion 1.459569e-3
GO:0060155 platelet dense granule organization 1.471678e-3
GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 1.471678e-3
GO:0001867 complement activation, lectin pathway 1.473030e-3
GO:0034380 high-density lipoprotein particle assembly 1.497121e-3
GO:0032526 response to retinoic acid 1.504031e-3
GO:0050765 negative regulation of phagocytosis 1.505795e-3
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 1.506993e-3
GO:0001503 ossification 1.515802e-3
GO:0043583 ear development 1.516588e-3
GO:0051135 positive regulation of NK T cell activation 1.526085e-3
GO:0061098 positive regulation of protein tyrosine kinase activity 1.562429e-3
GO:0048738 cardiac muscle tissue development 1.570209e-3
GO:0006756 AMP phosphorylation 1.591035e-3
GO:0050823 peptide antigen stabilization 1.591035e-3
GO:0032342 aldosterone biosynthetic process 1.591035e-3
GO:0002897 positive regulation of central B cell tolerance induction 1.591035e-3
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 1.591035e-3
GO:0002508 central tolerance induction 1.591035e-3
GO:0030501 positive regulation of bone mineralization 1.636363e-3
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 1.642399e-3
GO:0007267 cell-cell signaling 1.650281e-3
GO:0061035 regulation of cartilage development 1.657488e-3
GO:0046415 urate metabolic process 1.669201e-3
GO:0001969 regulation of activation of membrane attack complex 1.669748e-3
GO:0018193 peptidyl-amino acid modification 1.682612e-3
GO:0032649 regulation of interferon-gamma production 1.686818e-3
GO:0050771 negative regulation of axonogenesis 1.688469e-3
GO:0032615 interleukin-12 production 1.722193e-3
GO:0071205 protein localization to juxtaparanode region of axon 1.722193e-3
GO:0048535 lymph node development 1.724416e-3
GO:0019222 regulation of metabolic process 1.728374e-3
GO:0048144 fibroblast proliferation 1.744708e-3
GO:0031325 positive regulation of cellular metabolic process 1.780037e-3
GO:2000378 negative regulation of reactive oxygen species metabolic process 1.807271e-3
GO:0051050 positive regulation of transport 1.834737e-3
GO:0003015 heart process 1.851583e-3
GO:0008625 induction of apoptosis via death domain receptors 1.851635e-3
GO:0010887 negative regulation of cholesterol storage 1.872885e-3
GO:0060976 coronary vasculature development 1.878357e-3
GO:0032863 activation of Rac GTPase activity 1.897539e-3
GO:0010954 positive regulation of protein processing 1.897539e-3
GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 1.897539e-3
GO:0009236 cobalamin biosynthetic process 1.902027e-3
GO:0033120 positive regulation of RNA splicing 1.911061e-3
GO:0032000 positive regulation of fatty acid beta-oxidation 1.918977e-3
GO:0046320 regulation of fatty acid oxidation 1.928883e-3
GO:0006111 regulation of gluconeogenesis 1.988903e-3
GO:0046928 regulation of neurotransmitter secretion 1.995695e-3
GO:0045725 positive regulation of glycogen biosynthetic process 2.047899e-3
GO:0051899 membrane depolarization 2.052164e-3
GO:0001970 positive regulation of activation of membrane attack complex 2.073737e-3
GO:0007440 foregut morphogenesis 2.125118e-3
GO:0042823 pyridoxal phosphate biosynthetic process 2.135198e-3
GO:0031508 centromeric heterochromatin formation 2.135198e-3
GO:0032890 regulation of organic acid transport 2.147066e-3
GO:0050729 positive regulation of inflammatory response 2.153247e-3
GO:0048016 inositol phosphate-mediated signaling 2.189572e-3
GO:0050881 musculoskeletal movement 2.196139e-3