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Novel motif:138

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name:motif138_CTTTWANNYCC

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0042137 sequestering of neurotransmitter 2.688335e-18
GO:0016477 cell migration 8.204490e-11
GO:0006928 cellular component movement 8.389849e-10
GO:0044341 sodium-dependent phosphate transport 1.325896e-9
GO:0032908 regulation of transforming growth factor beta1 production 6.451633e-9
GO:0031915 positive regulation of synaptic plasticity 7.626818e-9
GO:0048870 cell motility 1.649507e-8
GO:0032914 positive regulation of transforming growth factor beta1 production 2.075403e-8
GO:0040011 locomotion 2.776102e-8
GO:0070302 regulation of stress-activated protein kinase signaling cascade 2.781795e-8
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3.563631e-8
GO:0006707 cholesterol catabolic process 5.123914e-8
GO:0042534 regulation of tumor necrosis factor biosynthetic process 5.963443e-8
GO:0071460 cellular response to cell-matrix adhesion 8.147122e-8
GO:0032891 negative regulation of organic acid transport 1.332823e-7
GO:0009313 oligosaccharide catabolic process 1.917567e-7
GO:0048676 axon extension involved in development 1.941224e-7
GO:0040007 growth 2.667906e-7
GO:0002687 positive regulation of leukocyte migration 2.874986e-7
GO:0006689 ganglioside catabolic process 3.051053e-7
GO:0061029 eyelid development in camera-type eye 3.442413e-7
GO:0006605 protein targeting 4.933405e-7
GO:0051179 localization 5.144366e-7
GO:0016125 sterol metabolic process 5.343923e-7
GO:0051895 negative regulation of focal adhesion assembly 7.922184e-7
GO:0030225 macrophage differentiation 8.003059e-7
GO:0002685 regulation of leukocyte migration 1.122415e-6
GO:0008203 cholesterol metabolic process 1.197065e-6
GO:0045766 positive regulation of angiogenesis 1.367710e-6
GO:0071229 cellular response to acid 1.764818e-6
GO:0010758 regulation of macrophage chemotaxis 1.777213e-6
GO:0071281 cellular response to iron ion 1.911919e-6
GO:0048589 developmental growth 1.974887e-6
GO:0080135 regulation of cellular response to stress 2.017913e-6
GO:0002690 positive regulation of leukocyte chemotaxis 2.075199e-6
GO:0051915 induction of synaptic plasticity by chemical substance 2.161761e-6
GO:0044140 negative regulation of growth of symbiont on or near host surface 2.318330e-6
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 2.591867e-6
GO:0045727 positive regulation of translation 2.708611e-6
GO:0046328 regulation of JNK cascade 2.734788e-6
GO:0010759 positive regulation of macrophage chemotaxis 2.960450e-6
GO:0050900 leukocyte migration 2.964258e-6
GO:0043200 response to amino acid stimulus 2.988235e-6
GO:0071295 cellular response to vitamin 3.035306e-6
GO:0006706 steroid catabolic process 3.469946e-6
GO:0043004 cytoplasmic sequestering of CFTR protein 4.095426e-6
GO:0046032 ADP catabolic process 4.195160e-6
GO:0046709 IDP catabolic process 4.195160e-6
GO:0071299 cellular response to vitamin A 4.268170e-6
GO:0043201 response to leucine 4.296322e-6
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 4.821557e-6
GO:0002448 mast cell mediated immunity 4.927471e-6
GO:0015827 tryptophan transport 5.122051e-6
GO:0032103 positive regulation of response to external stimulus 5.672725e-6
GO:0042108 positive regulation of cytokine biosynthetic process 5.708582e-6
GO:0001101 response to acid 5.747255e-6
GO:0050710 negative regulation of cytokine secretion 5.751009e-6
GO:0071675 regulation of mononuclear cell migration 6.770316e-6
GO:0060078 regulation of postsynaptic membrane potential 7.004552e-6
GO:0060996 dendritic spine development 7.527009e-6
GO:0043066 negative regulation of apoptosis 7.627223e-6
GO:0019087 transformation of host cell by virus 8.467573e-6
GO:0035621 ER to Golgi ceramide transport 9.872620e-6
GO:0048675 axon extension 1.012488e-5
GO:0046479 glycosphingolipid catabolic process 1.016385e-5
GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway 1.023271e-5
GO:0060997 dendritic spine morphogenesis 1.044126e-5
GO:2000106 regulation of leukocyte apoptosis 1.104632e-5
GO:0090116 C-5 methylation of cytosine 1.121024e-5
GO:0002688 regulation of leukocyte chemotaxis 1.179662e-5
GO:0017085 response to insecticide 1.180931e-5
GO:0006913 nucleocytoplasmic transport 1.206770e-5
GO:0002444 myeloid leukocyte mediated immunity 1.213932e-5
GO:0046330 positive regulation of JNK cascade 1.260392e-5
GO:0071636 positive regulation of transforming growth factor beta production 1.380443e-5
GO:0042035 regulation of cytokine biosynthetic process 1.406794e-5
GO:0023035 CD40 signaling pathway 1.462829e-5
GO:0043069 negative regulation of programmed cell death 1.641689e-5
GO:0044070 regulation of anion transport 1.796370e-5
GO:0060548 negative regulation of cell death 1.799446e-5
GO:0010876 lipid localization 2.032801e-5
GO:0019377 glycolipid catabolic process 2.049868e-5
GO:0017038 protein import 2.081181e-5
GO:0051169 nuclear transport 2.366668e-5
GO:0001937 negative regulation of endothelial cell proliferation 2.379472e-5
GO:0000422 mitochondrion degradation 2.458572e-5
GO:0019915 lipid storage 2.566504e-5
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 2.722405e-5
GO:0050902 leukocyte adhesive activation 2.722405e-5
GO:0015801 aromatic amino acid transport 2.732233e-5
GO:0002502 peptide antigen assembly with MHC class I protein complex 2.759136e-5
GO:0051168 nuclear export 2.790395e-5
GO:0048596 embryonic camera-type eye morphogenesis 2.794052e-5
GO:0071622 regulation of granulocyte chemotaxis 2.966967e-5
GO:0010596 negative regulation of endothelial cell migration 3.041162e-5
GO:0031114 regulation of microtubule depolymerization 3.210596e-5
GO:0031670 cellular response to nutrient 3.305673e-5
GO:0002683 negative regulation of immune system process 3.405700e-5
GO:0006325 chromatin organization 3.414760e-5
GO:0010754 negative regulation of cGMP-mediated signaling 3.579534e-5
GO:0043652 engulfment of apoptotic cell 3.579534e-5
GO:0010751 negative regulation of nitric oxide mediated signal transduction 3.579534e-5
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 3.579534e-5
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 3.579534e-5
GO:0061162 establishment of monopolar cell polarity 3.760255e-5
GO:0071300 cellular response to retinoic acid 3.792981e-5
GO:0050921 positive regulation of chemotaxis 3.943790e-5
GO:0002523 leukocyte migration involved in inflammatory response 4.066484e-5
GO:0002577 regulation of antigen processing and presentation 4.146533e-5
GO:0060900 embryonic camera-type eye formation 4.368347e-5
GO:0048048 embryonic eye morphogenesis 4.369557e-5
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 4.916106e-5
GO:0033026 negative regulation of mast cell apoptosis 4.934188e-5
GO:0021506 anterior neuropore closure 5.396143e-5
GO:0046325 negative regulation of glucose import 5.985514e-5
GO:0043170 macromolecule metabolic process 6.009902e-5
GO:0051893 regulation of focal adhesion assembly 6.142508e-5
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 6.558086e-5
GO:0016568 chromatin modification 6.710571e-5
GO:0042325 regulation of phosphorylation 6.821878e-5
GO:0010627 regulation of intracellular protein kinase cascade 7.607658e-5
GO:0045994 positive regulation of translational initiation by iron 8.460701e-5
GO:0002037 negative regulation of L-glutamate transport 8.460701e-5
GO:0032776 DNA methylation on cytosine 8.633360e-5
GO:0051938 L-glutamate import 8.673385e-5
GO:0031111 negative regulation of microtubule polymerization or depolymerization 8.699322e-5
GO:0060021 palate development 8.709380e-5
GO:0043536 positive regulation of blood vessel endothelial cell migration 8.798925e-5
GO:0006886 intracellular protein transport 8.916683e-5
GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity 9.448703e-5
GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway 9.448703e-5
GO:0009191 ribonucleoside diphosphate catabolic process 9.692215e-5
GO:0060079 regulation of excitatory postsynaptic membrane potential 1.010435e-4
GO:0006383 transcription from RNA polymerase III promoter 1.030087e-4
GO:0006116 NADH oxidation 1.036376e-4
GO:0007026 negative regulation of microtubule depolymerization 1.080331e-4
GO:0071283 cellular response to iron(III) ion 1.093315e-4
GO:0031860 telomeric 3' overhang formation 1.093315e-4
GO:0060623 regulation of chromosome condensation 1.093315e-4
GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 1.093315e-4
GO:0046680 response to DDT 1.093315e-4
GO:0048535 lymph node development 1.101453e-4
GO:0032680 regulation of tumor necrosis factor production 1.140186e-4
GO:0070887 cellular response to chemical stimulus 1.163155e-4
GO:0043535 regulation of blood vessel endothelial cell migration 1.186353e-4
GO:0048704 embryonic skeletal system morphogenesis 1.205363e-4
GO:2000296 negative regulation of hydrogen peroxide catabolic process 1.245186e-4
GO:0001932 regulation of protein phosphorylation 1.270313e-4
GO:0043537 negative regulation of blood vessel endothelial cell migration 1.288496e-4
GO:0015742 alpha-ketoglutarate transport 1.306775e-4
GO:0051956 negative regulation of amino acid transport 1.322366e-4
GO:0018149 peptide cross-linking 1.360425e-4
GO:0042246 tissue regeneration 1.378298e-4
GO:0014075 response to amine stimulus 1.384807e-4
GO:0048562 embryonic organ morphogenesis 1.394919e-4
GO:0071383 cellular response to steroid hormone stimulus 1.413944e-4
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 1.418472e-4
GO:0050863 regulation of T cell activation 1.427060e-4
GO:0034605 cellular response to heat 1.445716e-4
GO:0048532 anatomical structure arrangement 1.454626e-4
GO:0016358 dendrite development 1.456791e-4
GO:0042742 defense response to bacterium 1.481198e-4
GO:0043508 negative regulation of JUN kinase activity 1.496377e-4
GO:0046642 negative regulation of alpha-beta T cell proliferation 1.499485e-4
GO:0071233 cellular response to leucine 1.529676e-4
GO:0009590 detection of gravity 1.529676e-4
GO:0019220 regulation of phosphate metabolic process 1.535638e-4
GO:0010594 regulation of endothelial cell migration 1.541671e-4
GO:0070668 positive regulation of mast cell proliferation 1.566906e-4
GO:0006275 regulation of DNA replication 1.598065e-4
GO:0016049 cell growth 1.647822e-4
GO:0050930 induction of positive chemotaxis 1.668186e-4
GO:0045580 regulation of T cell differentiation 1.689733e-4
GO:0045773 positive regulation of axon extension 1.740475e-4
GO:0006611 protein export from nucleus 1.746105e-4
GO:0072384 organelle transport along microtubule 1.749366e-4
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.884448e-4
GO:0009605 response to external stimulus 1.906959e-4
GO:0051208 sequestering of calcium ion 1.999086e-4
GO:0070673 response to interleukin-18 2.034779e-4
GO:0009615 response to virus 2.113593e-4
GO:0035249 synaptic transmission, glutamatergic 2.158160e-4
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 2.254990e-4
GO:0001953 negative regulation of cell-matrix adhesion 2.265522e-4
GO:0002694 regulation of leukocyte activation 2.320204e-4
GO:0021623 oculomotor nerve formation 2.334381e-4
GO:0003409 optic cup structural organization 2.334381e-4
GO:0003404 optic vesicle morphogenesis 2.334381e-4
GO:0031399 regulation of protein modification process 2.400644e-4
GO:0030574 collagen catabolic process 2.424459e-4
GO:0031627 telomeric loop formation 2.428872e-4
GO:0051323 metaphase 2.431223e-4
GO:0050920 regulation of chemotaxis 2.458596e-4
GO:0051549 positive regulation of keratinocyte migration 2.551605e-4
GO:0051716 cellular response to stimulus 2.582608e-4
GO:0043030 regulation of macrophage activation 2.623316e-4
GO:0031668 cellular response to extracellular stimulus 2.633948e-4
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 2.646918e-4
GO:0043542 endothelial cell migration 2.649492e-4
GO:0043506 regulation of JUN kinase activity 2.657384e-4
GO:0010765 positive regulation of sodium ion transport 2.751394e-4
GO:0001819 positive regulation of cytokine production 2.763930e-4
GO:0033673 negative regulation of kinase activity 2.818245e-4
GO:0050789 regulation of biological process 2.829936e-4
GO:0043534 blood vessel endothelial cell migration 2.967993e-4
GO:0007132 meiotic metaphase I 2.973898e-4
GO:0048680 positive regulation of axon regeneration 3.128801e-4
GO:0047497 mitochondrion transport along microtubule 3.144526e-4
GO:0044243 multicellular organismal catabolic process 3.152741e-4
GO:0071230 cellular response to amino acid stimulus 3.196960e-4
GO:0032890 regulation of organic acid transport 3.446732e-4
GO:0051249 regulation of lymphocyte activation 3.467749e-4
GO:0046364 monosaccharide biosynthetic process 3.551764e-4
GO:0050794 regulation of cellular process 3.597537e-4
GO:0016998 cell wall macromolecule catabolic process 3.665552e-4
GO:0043405 regulation of MAP kinase activity 3.758901e-4
GO:0000165 MAPKKK cascade 3.760557e-4
GO:0014012 peripheral nervous system axon regeneration 3.788286e-4
GO:0010243 response to organic nitrogen 3.866793e-4
GO:0015813 L-glutamate transport 3.949645e-4
GO:0010763 positive regulation of fibroblast migration 3.957293e-4
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 3.965374e-4
GO:0043549 regulation of kinase activity 3.965903e-4
GO:0033504 floor plate development 4.035659e-4
GO:0015807 L-amino acid transport 4.111746e-4
GO:0001667 ameboidal cell migration 4.161669e-4
GO:0021758 putamen development 4.287071e-4
GO:0021757 caudate nucleus development 4.287071e-4
GO:0009408 response to heat 4.297143e-4
GO:0042997 negative regulation of Golgi to plasma membrane protein transport 4.327409e-4
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway 4.343787e-4
GO:0010629 negative regulation of gene expression 4.432259e-4
GO:0043032 positive regulation of macrophage activation 4.474739e-4
GO:0051649 establishment of localization in cell 4.534701e-4
GO:0044260 cellular macromolecule metabolic process 4.545821e-4
GO:0046466 membrane lipid catabolic process 4.599718e-4
GO:0033025 regulation of mast cell apoptosis 4.602256e-4
GO:0051301 cell division 4.716781e-4
GO:0040040 thermosensory behavior 4.773388e-4
GO:0006094 gluconeogenesis 4.797426e-4
GO:0010595 positive regulation of endothelial cell migration 4.849890e-4
GO:0010842 retina layer formation 4.882166e-4
GO:0043330 response to exogenous dsRNA 4.926252e-4
GO:0071396 cellular response to lipid 4.937175e-4
GO:0045619 regulation of lymphocyte differentiation 4.950949e-4
GO:0044036 cell wall macromolecule metabolic process 4.958038e-4
GO:0033189 response to vitamin A 5.128114e-4
GO:0051170 nuclear import 5.165162e-4
GO:0032494 response to peptidoglycan 5.313169e-4
GO:0042472 inner ear morphogenesis 5.319020e-4
GO:0002072 optic cup morphogenesis involved in camera-type eye development 5.354055e-4
GO:0021603 cranial nerve formation 5.476111e-4
GO:0051234 establishment of localization 5.540963e-4
GO:0045627 positive regulation of T-helper 1 cell differentiation 5.598896e-4
GO:0060363 cranial suture morphogenesis 5.639957e-4
GO:0051338 regulation of transferase activity 5.785432e-4
GO:0043408 regulation of MAPKKK cascade 5.806776e-4
GO:0006048 UDP-N-acetylglucosamine biosynthetic process 5.843271e-4
GO:0002696 positive regulation of leukocyte activation 5.844240e-4
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 5.852340e-4
GO:0060004 reflex 5.904691e-4
GO:0006447 regulation of translational initiation by iron 5.941140e-4
GO:0033036 macromolecule localization 5.948578e-4
GO:0071224 cellular response to peptidoglycan 5.949314e-4
GO:0042221 response to chemical stimulus 5.979253e-4
GO:0048333 mesodermal cell differentiation 6.000261e-4
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 6.033454e-4
GO:0015696 ammonium transport 6.099337e-4
GO:0071404 cellular response to low-density lipoprotein particle stimulus 6.099337e-4
GO:0006991 response to sterol depletion 6.101357e-4
GO:0048520 positive regulation of behavior 6.140929e-4
GO:0000244 assembly of spliceosomal tri-snRNP 6.150142e-4
GO:0046349 amino sugar biosynthetic process 6.356841e-4
GO:0051276 chromosome organization 6.483762e-4
GO:0006954 inflammatory response 6.493323e-4
GO:0031076 embryonic camera-type eye development 6.738971e-4
GO:0071470 cellular response to osmotic stress 6.780019e-4
GO:0006695 cholesterol biosynthetic process 6.793216e-4
GO:0043901 negative regulation of multi-organism process 6.877885e-4
GO:0051348 negative regulation of transferase activity 6.943172e-4
GO:0051295 establishment of meiotic spindle localization 6.971006e-4
GO:0007019 microtubule depolymerization 7.112444e-4
GO:0016126 sterol biosynthetic process 7.208112e-4
GO:0006469 negative regulation of protein kinase activity 7.307718e-4
GO:0071402 cellular response to lipoprotein particle stimulus 7.392191e-4
GO:0050865 regulation of cell activation 7.397758e-4
GO:0030501 positive regulation of bone mineralization 7.409190e-4
GO:0031440 regulation of mRNA 3'-end processing 7.474292e-4
GO:0030278 regulation of ossification 7.545003e-4
GO:0002376 immune system process 7.627034e-4
GO:0071474 cellular hyperosmotic response 7.908002e-4
GO:2000377 regulation of reactive oxygen species metabolic process 8.085396e-4
GO:0006338 chromatin remodeling 8.149729e-4
GO:0006606 protein import into nucleus 8.154667e-4
GO:0050892 intestinal absorption 8.342459e-4
GO:0035695 mitochondrion degradation by induced vacuole formation 8.349763e-4
GO:0014739 positive regulation of muscle hyperplasia 8.349763e-4
GO:0030149 sphingolipid catabolic process 8.375465e-4
GO:0009790 embryo development 8.397498e-4
GO:0015031 protein transport 8.412446e-4
GO:0006810 transport 8.575305e-4
GO:2000108 positive regulation of leukocyte apoptosis 8.791507e-4
GO:0045778 positive regulation of ossification 8.841101e-4
GO:0002532 production of molecular mediator involved in inflammatory response 8.849802e-4
GO:0033143 regulation of steroid hormone receptor signaling pathway 8.857633e-4
GO:0002819 regulation of adaptive immune response 8.957839e-4
GO:0015800 acidic amino acid transport 8.995454e-4
GO:0070071 proton-transporting two-sector ATPase complex assembly 9.154670e-4
GO:0007501 mesodermal cell fate specification 9.315022e-4
GO:0065007 biological regulation 9.456023e-4
GO:0001775 cell activation 9.517533e-4
GO:0048588 developmental cell growth 9.591253e-4
GO:0000375 RNA splicing, via transesterification reactions 9.647137e-4
GO:0071418 cellular response to amine stimulus 9.759872e-4
GO:0014020 primary neural tube formation 1.007654e-3
GO:0016569 covalent chromatin modification 1.008546e-3
GO:0001710 mesodermal cell fate commitment 1.008753e-3
GO:0006935 chemotaxis 1.013943e-3
GO:0050870 positive regulation of T cell activation 1.023527e-3
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 1.026734e-3
GO:0007018 microtubule-based movement 1.060855e-3
GO:0033145 positive regulation of steroid hormone receptor signaling pathway 1.070256e-3
GO:0000910 cytokinesis 1.080546e-3
GO:0045859 regulation of protein kinase activity 1.135874e-3
GO:0016925 protein sumoylation 1.165222e-3
GO:2000275 regulation of oxidative phosphorylation uncoupler activity 1.167541e-3
GO:0071712 ER-associated misfolded protein catabolic process 1.171319e-3
GO:0002536 respiratory burst involved in inflammatory response 1.183101e-3
GO:0006734 NADH metabolic process 1.205239e-3
GO:0007389 pattern specification process 1.205538e-3
GO:0030299 intestinal cholesterol absorption 1.206323e-3
GO:0044238 primary metabolic process 1.213740e-3
GO:0043243 positive regulation of protein complex disassembly 1.222693e-3
GO:0042471 ear morphogenesis 1.235477e-3
GO:0061028 establishment of endothelial barrier 1.235992e-3
GO:0002315 marginal zone B cell differentiation 1.266263e-3
GO:0045064 T-helper 2 cell differentiation 1.266263e-3
GO:0001841 neural tube formation 1.275686e-3
GO:0006952 defense response 1.296925e-3
GO:0009181 purine ribonucleoside diphosphate catabolic process 1.305209e-3
GO:0060264 regulation of respiratory burst involved in inflammatory response 1.308780e-3
GO:0071417 cellular response to organic nitrogen 1.319959e-3
GO:0070169 positive regulation of biomineral tissue development 1.329868e-3
GO:0001944 vasculature development 1.330261e-3
GO:0010966 regulation of phosphate transport 1.342277e-3
GO:0032502 developmental process 1.369938e-3
GO:0016042 lipid catabolic process 1.378995e-3
GO:0034637 cellular carbohydrate biosynthetic process 1.386717e-3
GO:0050709 negative regulation of protein secretion 1.391202e-3
GO:0002011 morphogenesis of an epithelial sheet 1.392569e-3
GO:0001843 neural tube closure 1.412740e-3
GO:0055067 monovalent inorganic cation homeostasis 1.417621e-3
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.438894e-3
GO:0045740 positive regulation of DNA replication 1.467297e-3
GO:0002520 immune system development 1.469150e-3
GO:0048646 anatomical structure formation involved in morphogenesis 1.487183e-3
GO:0009987 cellular process 1.521297e-3
GO:0002036 regulation of L-glutamate transport 1.552476e-3
GO:0016576 histone dephosphorylation 1.552476e-3
GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1.556834e-3
GO:0040038 polar body extrusion after meiotic divisions 1.581222e-3
GO:0034504 protein localization to nucleus 1.596478e-3
GO:0045132 meiotic chromosome segregation 1.613220e-3
GO:0043406 positive regulation of MAP kinase activity 1.621606e-3
GO:0006664 glycolipid metabolic process 1.627834e-3
GO:0006351 transcription, DNA-dependent 1.637995e-3
GO:0051953 negative regulation of amine transport 1.656224e-3
GO:0051043 regulation of membrane protein ectodomain proteolysis 1.664168e-3
GO:0050867 positive regulation of cell activation 1.676208e-3
GO:0046640 regulation of alpha-beta T cell proliferation 1.682821e-3
GO:0002544 chronic inflammatory response 1.682991e-3
GO:0046324 regulation of glucose import 1.684711e-3
GO:0048534 hemopoietic or lymphoid organ development 1.710623e-3
GO:0006694 steroid biosynthetic process 1.720386e-3
GO:0009892 negative regulation of metabolic process 1.775465e-3
GO:0048280 vesicle fusion with Golgi apparatus 1.788143e-3
GO:0010996 response to auditory stimulus 1.788143e-3
GO:0030500 regulation of bone mineralization 1.788844e-3
GO:0048496 maintenance of organ identity 1.798122e-3
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 1.798122e-3
GO:0045663 positive regulation of myoblast differentiation 1.806636e-3
GO:0051097 negative regulation of helicase activity 1.812331e-3
GO:0045082 positive regulation of interleukin-10 biosynthetic process 1.814621e-3
GO:0021602 cranial nerve morphogenesis 1.829037e-3
GO:0000398 nuclear mRNA splicing, via spliceosome 1.911843e-3
GO:0051247 positive regulation of protein metabolic process 1.930786e-3
GO:0019428 allantoin biosynthetic process 1.934095e-3
GO:0050830 defense response to Gram-positive bacterium 1.937121e-3
GO:0007166 cell surface receptor linked signaling pathway 1.939109e-3
GO:0030097 hemopoiesis 1.941291e-3
GO:0006073 cellular glucan metabolic process 1.990761e-3
GO:0060606 tube closure 1.999961e-3
GO:0043092 L-amino acid import 2.033357e-3
GO:0035767 endothelial cell chemotaxis 2.058162e-3
GO:0043090 amino acid import 2.101113e-3
GO:0045765 regulation of angiogenesis 2.206011e-3
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 2.214790e-3
GO:2000378 negative regulation of reactive oxygen species metabolic process 2.233227e-3
GO:0010829 negative regulation of glucose transport 2.233227e-3
GO:0008625 induction of apoptosis via death domain receptors 2.233227e-3
GO:0030099 myeloid cell differentiation 2.278502e-3
GO:0021545 cranial nerve development 2.287670e-3
GO:0016570 histone modification 2.343544e-3
GO:0070228 regulation of lymphocyte apoptosis 2.362747e-3
GO:0009301 snRNA transcription 2.373805e-3
GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase 2.413420e-3
GO:0016198 axon choice point recognition 2.424304e-3
GO:0032743 positive regulation of interleukin-2 production 2.426180e-3
GO:2001014 regulation of skeletal muscle cell differentiation 2.454486e-3
GO:0070588 calcium ion transmembrane transport 2.454702e-3
GO:0033033 negative regulation of myeloid cell apoptosis 2.461962e-3
GO:0070170 regulation of tooth mineralization 2.465608e-3
GO:0008380 RNA splicing 2.473362e-3
GO:0030279 negative regulation of ossification 2.476540e-3
GO:0051917 regulation of fibrinolysis 2.486827e-3
GO:0007270 neuron-neuron synaptic transmission 2.493002e-3
GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis 2.526654e-3
GO:0071900 regulation of protein serine/threonine kinase activity 2.541296e-3
GO:0009611 response to wounding 2.561429e-3
GO:0051897 positive regulation of protein kinase B signaling cascade 2.598096e-3
GO:0050918 positive chemotaxis 2.631385e-3
GO:0032608 interferon-beta production 2.672919e-3
GO:0032872 regulation of stress-activated MAPK cascade 2.679141e-3
GO:0007289 spermatid nucleus differentiation 2.688670e-3
GO:0030516 regulation of axon extension 2.708677e-3
GO:0031295 T cell costimulation 2.727827e-3
GO:0044130 negative regulation of growth of symbiont in host 2.728385e-3
GO:0051654 establishment of mitochondrion localization 2.757028e-3
GO:0032268 regulation of cellular protein metabolic process 2.819421e-3
GO:0001756 somitogenesis 2.859492e-3
GO:0046684 response to pyrethroid 2.883272e-3
GO:0006931 substrate-dependent cell migration, cell attachment to substrate 2.883272e-3
GO:0006911 phagocytosis, engulfment 2.886382e-3
GO:0018199 peptidyl-glutamine modification 2.892258e-3
GO:0007165 signal transduction 2.927442e-3
GO:2000191 regulation of fatty acid transport 2.932759e-3
GO:0034694 response to prostaglandin stimulus 2.952493e-3
GO:0003334 keratinocyte development 2.980037e-3
GO:0006417 regulation of translation 2.990936e-3
GO:0045123 cellular extravasation 2.997031e-3
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 3.000520e-3
GO:0010812 negative regulation of cell-substrate adhesion 3.010139e-3
GO:0006607 NLS-bearing substrate import into nucleus 3.015523e-3
GO:0006817 phosphate ion transport 3.036134e-3
GO:0031112 positive regulation of microtubule polymerization or depolymerization 3.061754e-3
GO:0009088 threonine biosynthetic process 3.078638e-3
GO:0032606 type I interferon production 3.080377e-3
GO:0071634 regulation of transforming growth factor beta production 3.117988e-3
GO:0044314 protein K27-linked ubiquitination 3.134260e-3
GO:0035567 non-canonical Wnt receptor signaling pathway 3.151687e-3
GO:0045084 positive regulation of interleukin-12 biosynthetic process 3.155189e-3
GO:0042060 wound healing 3.177364e-3
GO:0033365 protein localization to organelle 3.193190e-3
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 3.195215e-3
GO:0005977 glycogen metabolic process 3.217924e-3
GO:0015858 nucleoside transport 3.223584e-3
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 3.232704e-3
GO:0070167 regulation of biomineral tissue development 3.234457e-3
GO:0032148 activation of protein kinase B activity 3.255778e-3
GO:0042536 negative regulation of tumor necrosis factor biosynthetic process 3.278707e-3
GO:0019730 antimicrobial humoral response 3.333184e-3
GO:0007042 lysosomal lumen acidification 3.333184e-3
GO:0051250 negative regulation of lymphocyte activation 3.348379e-3
GO:0045625 regulation of T-helper 1 cell differentiation 3.440820e-3
GO:0006687 glycosphingolipid metabolic process 3.458333e-3
GO:0032873 negative regulation of stress-activated MAPK cascade 3.463366e-3
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3.483907e-3
GO:0009967 positive regulation of signal transduction 3.504955e-3
GO:0045184 establishment of protein localization 3.513852e-3
GO:0006811 ion transport 3.516226e-3
GO:0002709 regulation of T cell mediated immunity 3.532413e-3
GO:0001707 mesoderm formation 3.578834e-3
GO:2001021 negative regulation of response to DNA damage stimulus 3.580737e-3
GO:0071379 cellular response to prostaglandin stimulus 3.583446e-3
GO:0035418 protein localization to synapse 3.583446e-3
GO:0031110 regulation of microtubule polymerization or depolymerization 3.599494e-3
GO:0035419 activation of MAPK activity involved in innate immune response 3.604153e-3
GO:0070172 positive regulation of tooth mineralization 3.626999e-3
GO:2000463 positive regulation of excitatory postsynaptic membrane potential 3.665983e-3
GO:0007231 osmosensory signaling pathway 3.739853e-3
GO:0007420 brain development 3.802752e-3
GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process 3.815311e-3
GO:0060390 regulation of SMAD protein import into nucleus 3.825796e-3
GO:0043401 steroid hormone mediated signaling pathway 3.866754e-3
GO:0060754 positive regulation of mast cell chemotaxis 3.872616e-3
GO:0014738 regulation of muscle hyperplasia 3.883847e-3
GO:0030573 bile acid catabolic process 3.892409e-3
GO:0051172 negative regulation of nitrogen compound metabolic process 4.001728e-3
GO:0009059 macromolecule biosynthetic process 4.004354e-3
GO:0048856 anatomical structure development 4.022432e-3
GO:0001768 establishment of T cell polarity 4.027468e-3
GO:0048706 embryonic skeletal system development 4.059764e-3
GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger 4.081297e-3
GO:0002030 inhibitory G-protein coupled receptor phosphorylation 4.086396e-3
GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 4.102640e-3
GO:0033205 cell cycle cytokinesis 4.133362e-3
GO:0051240 positive regulation of multicellular organismal process 4.150133e-3
GO:0045621 positive regulation of lymphocyte differentiation 4.228195e-3
GO:0050729 positive regulation of inflammatory response 4.267287e-3
GO:0060266 negative regulation of respiratory burst involved in inflammatory response 4.271672e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:2000253 positive regulation of feeding behavior 2.049210e-8
GO:2000507 positive regulation of energy homeostasis 2.049210e-8
GO:0072539 T-helper 17 cell differentiation 3.372211e-8
GO:0043407 negative regulation of MAP kinase activity 3.878247e-8
GO:0071168 protein localization to chromatin 1.131136e-7
GO:2000505 regulation of energy homeostasis 1.535312e-7
GO:0014816 satellite cell differentiation 2.938598e-7
GO:0071169 establishment of protein localization to chromatin 3.435793e-7
GO:0034435 cholesterol esterification 6.554814e-7
GO:0071901 negative regulation of protein serine/threonine kinase activity 1.152920e-6
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 1.305434e-6
GO:0046356 acetyl-CoA catabolic process 1.940216e-6
GO:0060041 retina development in camera-type eye 2.355084e-6
GO:0007128 meiotic prophase I 2.578509e-6
GO:0009109 coenzyme catabolic process 3.496151e-6
GO:0051187 cofactor catabolic process 3.813542e-6
GO:0071822 protein complex subunit organization 6.972345e-6
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 1.180492e-5
GO:0007127 meiosis I 1.183137e-5
GO:0045807 positive regulation of endocytosis 1.248689e-5
GO:0006084 acetyl-CoA metabolic process 1.552175e-5
GO:0060259 regulation of feeding behavior 1.861888e-5
GO:0006099 tricarboxylic acid cycle 1.930612e-5
GO:0032025 response to cobalt ion 2.045183e-5
GO:0010738 regulation of protein kinase A signaling cascade 2.046477e-5
GO:0016579 protein deubiquitination 2.060333e-5
GO:0032365 intracellular lipid transport 2.114217e-5
GO:0022027 interkinetic nuclear migration 2.296990e-5
GO:0070192 chromosome organization involved in meiosis 2.335043e-5
GO:0017126 nucleologenesis 2.415542e-5
GO:0030517 negative regulation of axon extension 2.634649e-5
GO:0030258 lipid modification 3.056914e-5
GO:0007129 synapsis 3.059873e-5
GO:0048241 epinephrine transport 3.293769e-5
GO:0006461 protein complex assembly 3.438902e-5
GO:0034097 response to cytokine stimulus 3.671983e-5
GO:0048522 positive regulation of cellular process 3.986071e-5
GO:0060059 embryonic retina morphogenesis in camera-type eye 4.198381e-5
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 4.206878e-5
GO:0006805 xenobiotic metabolic process 4.254355e-5
GO:0070271 protein complex biogenesis 4.480012e-5
GO:0072592 oxygen metabolic process 4.809886e-5
GO:0015721 bile acid and bile salt transport 5.330140e-5
GO:0009744 response to sucrose stimulus 5.330140e-5
GO:0048518 positive regulation of biological process 5.409794e-5
GO:0034502 protein localization to chromosome 5.520048e-5
GO:0009069 serine family amino acid metabolic process 5.775021e-5
GO:0046709 IDP catabolic process 6.000963e-5
GO:0046032 ADP catabolic process 6.000963e-5
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 6.347879e-5
GO:0019428 allantoin biosynthetic process 6.503500e-5
GO:0000279 M phase 6.685726e-5
GO:0070193 synaptonemal complex organization 6.939122e-5
GO:0045333 cellular respiration 7.013572e-5
GO:0010594 regulation of endothelial cell migration 7.031947e-5
GO:0021512 spinal cord anterior/posterior patterning 7.305832e-5
GO:0042130 negative regulation of T cell proliferation 8.688416e-5
GO:0071398 cellular response to fatty acid 8.811258e-5
GO:0010739 positive regulation of protein kinase A signaling cascade 9.063128e-5
GO:0006547 histidine metabolic process 9.182290e-5
GO:0000188 inactivation of MAPK activity 9.411375e-5
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 9.568794e-5
GO:0001525 angiogenesis 9.901532e-5
GO:0006833 water transport 9.940471e-5
GO:0046642 negative regulation of alpha-beta T cell proliferation 1.008841e-4
GO:0006102 isocitrate metabolic process 1.067474e-4
GO:0006734 NADH metabolic process 1.134251e-4
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 1.207994e-4
GO:0032792 negative regulation of CREB transcription factor activity 1.235848e-4
GO:0032065 cortical protein anchoring 1.305278e-4
GO:0000027 ribosomal large subunit assembly 1.305278e-4
GO:0000105 histidine biosynthetic process 1.460365e-4
GO:0009191 ribonucleoside diphosphate catabolic process 1.506965e-4
GO:0070367 negative regulation of hepatocyte differentiation 1.515193e-4
GO:0022417 protein maturation by protein folding 1.571829e-4
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 1.571829e-4
GO:0042044 fluid transport 1.603267e-4
GO:0043409 negative regulation of MAPKKK cascade 1.647863e-4
GO:0043623 cellular protein complex assembly 1.661848e-4
GO:0030225 macrophage differentiation 1.833694e-4
GO:0009410 response to xenobiotic stimulus 1.880274e-4
GO:0032367 intracellular cholesterol transport 1.892274e-4
GO:0002021 response to dietary excess 1.938511e-4
GO:0080164 regulation of nitric oxide metabolic process 2.025195e-4
GO:0007062 sister chromatid cohesion 2.093675e-4
GO:0006544 glycine metabolic process 2.331194e-4
GO:0045665 negative regulation of neuron differentiation 2.371024e-4
GO:0033762 response to glucagon stimulus 2.401509e-4
GO:0019674 NAD metabolic process 2.445837e-4
GO:0030953 astral microtubule organization 2.462242e-4
GO:0022403 cell cycle phase 2.483950e-4
GO:0060291 long-term synaptic potentiation 2.688571e-4
GO:0070542 response to fatty acid 2.831798e-4
GO:0043933 macromolecular complex subunit organization 2.928488e-4
GO:0000238 zygotene 3.053671e-4
GO:0001944 vasculature development 3.160627e-4
GO:0009134 nucleoside diphosphate catabolic process 3.189713e-4
GO:0022900 electron transport chain 3.275230e-4
GO:0018343 protein farnesylation 3.657557e-4
GO:0033034 positive regulation of myeloid cell apoptosis 3.715136e-4
GO:0071285 cellular response to lithium ion 3.910760e-4
GO:0021764 amygdala development 3.936772e-4
GO:0015791 polyol transport 4.012293e-4
GO:0070646 protein modification by small protein removal 4.078725e-4
GO:0045787 positive regulation of cell cycle 4.184577e-4
GO:0007130 synaptonemal complex assembly 4.268422e-4
GO:0045591 positive regulation of regulatory T cell differentiation 4.291899e-4
GO:0071383 cellular response to steroid hormone stimulus 4.369415e-4
GO:0006983 ER overload response 4.645160e-4
GO:0006548 histidine catabolic process 4.789860e-4
GO:0046499 S-adenosylmethioninamine metabolic process 4.852805e-4
GO:0070498 interleukin-1-mediated signaling pathway 5.004087e-4
GO:0030836 positive regulation of actin filament depolymerization 5.161235e-4
GO:0009185 ribonucleoside diphosphate metabolic process 5.360734e-4
GO:0051258 protein polymerization 5.429108e-4
GO:0006507 GPI anchor release 5.477468e-4
GO:2000178 negative regulation of neural precursor cell proliferation 5.506738e-4
GO:0006620 posttranslational protein targeting to membrane 5.564503e-4
GO:0009299 mRNA transcription 5.623244e-4
GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide 5.623244e-4
GO:0071310 cellular response to organic substance 5.677460e-4
GO:0060627 regulation of vesicle-mediated transport 5.725731e-4
GO:0006584 catecholamine metabolic process 5.941487e-4
GO:0007220 Notch receptor processing 5.986631e-4
GO:0051592 response to calcium ion 6.109662e-4
GO:0006108 malate metabolic process 6.120445e-4
GO:0045132 meiotic chromosome segregation 6.175301e-4
GO:0051900 regulation of mitochondrial depolarization 6.333132e-4
GO:0044092 negative regulation of molecular function 6.400997e-4
GO:0002268 follicular dendritic cell differentiation 6.738322e-4
GO:0048514 blood vessel morphogenesis 6.874863e-4
GO:0060042 retina morphogenesis in camera-type eye 6.921725e-4
GO:0009755 hormone-mediated signaling pathway 7.052646e-4
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 7.246029e-4
GO:0010038 response to metal ion 7.427786e-4
GO:0071345 cellular response to cytokine stimulus 7.761714e-4
GO:0006469 negative regulation of protein kinase activity 7.805676e-4
GO:0061180 mammary gland epithelium development 7.808837e-4
GO:0031589 cell-substrate adhesion 7.926431e-4
GO:0044027 hypermethylation of CpG island 8.224843e-4
GO:0046618 drug export 8.264134e-4
GO:0048193 Golgi vesicle transport 8.372726e-4
GO:0002687 positive regulation of leukocyte migration 8.653140e-4
GO:0051186 cofactor metabolic process 8.655024e-4
GO:0034440 lipid oxidation 8.704676e-4
GO:0007131 reciprocal meiotic recombination 9.086914e-4
GO:0043950 positive regulation of cAMP-mediated signaling 9.121499e-4
GO:0032608 interferon-beta production 9.121499e-4
GO:0070165 positive regulation of adiponectin secretion 9.159759e-4
GO:0033031 positive regulation of neutrophil apoptosis 9.159759e-4
GO:0060409 positive regulation of acetylcholine metabolic process 9.213257e-4
GO:0006829 zinc ion transport 9.536232e-4
GO:0060644 mammary gland epithelial cell differentiation 1.004088e-3
GO:0051716 cellular response to stimulus 1.028633e-3
GO:0010948 negative regulation of cell cycle process 1.029301e-3
GO:0048242 epinephrine secretion 1.076782e-3
GO:0070366 regulation of hepatocyte differentiation 1.082416e-3
GO:0042415 norepinephrine metabolic process 1.086618e-3
GO:0007166 cell surface receptor linked signaling pathway 1.089835e-3
GO:0033240 positive regulation of cellular amine metabolic process 1.154657e-3
GO:0051901 positive regulation of mitochondrial depolarization 1.167564e-3
GO:0045143 homologous chromosome segregation 1.167564e-3
GO:0007229 integrin-mediated signaling pathway 1.187645e-3
GO:0001568 blood vessel development 1.198336e-3
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 1.207210e-3
GO:0048260 positive regulation of receptor-mediated endocytosis 1.208232e-3
GO:0065003 macromolecular complex assembly 1.255424e-3
GO:0051546 keratinocyte migration 1.260671e-3
GO:0006564 L-serine biosynthetic process 1.260671e-3
GO:0043401 steroid hormone mediated signaling pathway 1.281384e-3
GO:0033687 osteoblast proliferation 1.290623e-3
GO:0046031 ADP metabolic process 1.290623e-3
GO:0003180 aortic valve morphogenesis 1.304422e-3
GO:0048103 somatic stem cell division 1.307165e-3
GO:0033673 negative regulation of kinase activity 1.357299e-3
GO:0048692 negative regulation of axon extension involved in regeneration 1.399657e-3
GO:2000016 negative regulation of determination of dorsal identity 1.399657e-3
GO:0006710 androgen catabolic process 1.399657e-3
GO:0060749 mammary gland alveolus development 1.416001e-3
GO:0032914 positive regulation of transforming growth factor beta1 production 1.429117e-3
GO:0048640 negative regulation of developmental growth 1.436854e-3
GO:0032594 protein transport within lipid bilayer 1.441934e-3
GO:0030967 ER-nuclear sterol response pathway 1.441934e-3
GO:0022402 cell cycle process 1.484047e-3
GO:0017145 stem cell division 1.497829e-3
GO:0043604 amide biosynthetic process 1.594099e-3
GO:0070887 cellular response to chemical stimulus 1.629809e-3
GO:0030100 regulation of endocytosis 1.641214e-3
GO:0072109 glomerular mesangium development 1.650649e-3
GO:0010033 response to organic substance 1.655608e-3
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 1.663883e-3
GO:2000386 positive regulation of ovarian follicle development 1.697820e-3
GO:2000388 positive regulation of antral ovarian follicle growth 1.697820e-3
GO:2000368 positive regulation of acrosomal vesicle exocytosis 1.697820e-3
GO:0070370 cellular heat acclimation 1.697820e-3
GO:0010513 positive regulation of phosphatidylinositol biosynthetic process 1.697820e-3
GO:0042666 negative regulation of ectodermal cell fate specification 1.697820e-3
GO:0001809 positive regulation of type IV hypersensitivity 1.697820e-3
GO:0034621 cellular macromolecular complex subunit organization 1.774803e-3
GO:0002088 lens development in camera-type eye 1.793425e-3
GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation 1.810448e-3
GO:0006984 ER-nucleus signaling pathway 1.811008e-3
GO:0009070 serine family amino acid biosynthetic process 1.832852e-3
GO:0010866 regulation of triglyceride biosynthetic process 1.841998e-3
GO:0046013 regulation of T cell homeostatic proliferation 1.861709e-3
GO:0002444 myeloid leukocyte mediated immunity 1.869074e-3
GO:0051348 negative regulation of transferase activity 1.869904e-3
GO:0045598 regulation of fat cell differentiation 1.879417e-3
GO:0010811 positive regulation of cell-substrate adhesion 1.961712e-3
GO:0034224 cellular response to zinc ion starvation 1.971503e-3
GO:0048822 enucleate erythrocyte development 2.006555e-3
GO:0045726 positive regulation of integrin biosynthetic process 2.006555e-3
GO:0016042 lipid catabolic process 2.052904e-3
GO:0070293 renal absorption 2.055453e-3
GO:0045859 regulation of protein kinase activity 2.132174e-3
GO:0010193 response to ozone 2.196781e-3
GO:0007165 signal transduction 2.233777e-3
GO:0040007 growth 2.241266e-3
GO:0035562 negative regulation of chromatin binding 2.242465e-3
GO:0006994 positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway 2.242465e-3
GO:0017144 drug metabolic process 2.279517e-3
GO:0061311 cell surface receptor linked signaling pathway involved in heart development 2.333612e-3
GO:0045626 negative regulation of T-helper 1 cell differentiation 2.337619e-3
GO:0016180 snRNA processing 2.363702e-3
GO:0048537 mucosal-associated lymphoid tissue development 2.415830e-3
GO:0009583 detection of light stimulus 2.422657e-3
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 2.423819e-3
GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity 2.486872e-3
GO:0014005 microglia development 2.486872e-3
GO:0009956 radial pattern formation 2.495217e-3
GO:0007140 male meiosis 2.566076e-3
GO:0051050 positive regulation of transport 2.632276e-3
GO:0010741 negative regulation of intracellular protein kinase cascade 2.696873e-3
GO:0006290 pyrimidine dimer repair 2.709535e-3
GO:0016322 neuron remodeling 2.738788e-3
GO:0071396 cellular response to lipid 2.749938e-3
GO:0045822 negative regulation of heart contraction 2.808990e-3
GO:0002690 positive regulation of leukocyte chemotaxis 2.951838e-3
GO:0010873 positive regulation of cholesterol esterification 3.007292e-3
GO:0045760 positive regulation of action potential 3.024087e-3
GO:0048489 synaptic vesicle transport 3.115803e-3
GO:0010243 response to organic nitrogen 3.259845e-3
GO:0006949 syncytium formation 3.269297e-3
GO:0007602 phototransduction 3.281954e-3
GO:0070543 response to linoleic acid 3.294303e-3
GO:0045875 negative regulation of sister chromatid cohesion 3.294303e-3
GO:0034014 response to triglyceride 3.294303e-3
GO:0034696 response to prostaglandin F stimulus 3.294303e-3
GO:0003097 renal water transport 3.315986e-3
GO:0051130 positive regulation of cellular component organization 3.476110e-3
GO:0071248 cellular response to metal ion 3.522665e-3
GO:0043535 regulation of blood vessel endothelial cell migration 3.538754e-3
GO:0019221 cytokine-mediated signaling pathway 3.571427e-3
GO:0014821 phasic smooth muscle contraction 3.611082e-3
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 3.613259e-3
GO:0070194 synaptonemal complex disassembly 3.619433e-3
GO:0051775 response to redox state 3.619433e-3
GO:0048015 phosphatidylinositol-mediated signaling 3.635568e-3
GO:0032410 negative regulation of transporter activity 3.673690e-3
GO:0060136 embryonic process involved in female pregnancy 3.675018e-3
GO:0042789 mRNA transcription from RNA polymerase II promoter 3.680023e-3
GO:0035315 hair cell differentiation 3.680023e-3
GO:0009719 response to endogenous stimulus 3.693041e-3
GO:0010627 regulation of intracellular protein kinase cascade 3.700800e-3
GO:0007527 adult somatic muscle development 3.830734e-3
GO:0071346 cellular response to interferon-gamma 3.844137e-3
GO:0050687 negative regulation of defense response to virus 3.884056e-3
GO:0046381 CMP-N-acetylneuraminate metabolic process 3.884056e-3
GO:0006892 post-Golgi vesicle-mediated transport 3.896127e-3
GO:0060026 convergent extension 3.968158e-3
GO:0010595 positive regulation of endothelial cell migration 3.977992e-3
GO:0009060 aerobic respiration 4.007917e-3
GO:0046951 ketone body biosynthetic process 4.012600e-3
GO:0048741 skeletal muscle fiber development 4.012766e-3
GO:0034501 protein localization to kinetochore 4.028168e-3
GO:0006939 smooth muscle contraction 4.046004e-3
GO:0010632 regulation of epithelial cell migration 4.097023e-3
GO:0007219 Notch signaling pathway 4.149200e-3
GO:0042127 regulation of cell proliferation 4.157203e-3
GO:0010226 response to lithium ion 4.167597e-3
GO:0007059 chromosome segregation 4.172303e-3
GO:0021772 olfactory bulb development 4.205281e-3
GO:0045047 protein targeting to ER 4.348488e-3
GO:0045589 regulation of regulatory T cell differentiation 4.357246e-3
GO:0010868 negative regulation of triglyceride biosynthetic process 4.357246e-3
GO:0021988 olfactory lobe development 4.443703e-3
GO:0019395 fatty acid oxidation 4.486256e-3
GO:0051647 nucleus localization 4.559011e-3
GO:0051930 regulation of sensory perception of pain 4.573989e-3
GO:0045165 cell fate commitment 4.592356e-3
GO:0010046 response to mycotoxin 4.683893e-3
GO:0034341 response to interferon-gamma 4.747454e-3
GO:0010624 regulation of Schwann cell proliferation 4.769191e-3
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 4.832920e-3
GO:0071900 regulation of protein serine/threonine kinase activity 4.988916e-3
GO:0000387 spliceosomal snRNP assembly 5.056612e-3
GO:0048520 positive regulation of behavior 5.176833e-3
GO:0045956 positive regulation of calcium ion-dependent exocytosis 5.197638e-3
GO:0015850 organic alcohol transport 5.214314e-3
GO:0009893 positive regulation of metabolic process 5.253643e-3
GO:0033313 meiotic cell cycle checkpoint 5.253922e-3
GO:0010996 response to auditory stimulus 5.253922e-3
GO:0042138 meiotic DNA double-strand break formation 5.253922e-3
GO:0006427 histidyl-tRNA aminoacylation 5.253922e-3
GO:0010085 polarity specification of proximal/distal axis 5.253922e-3
GO:0009786 regulation of asymmetric cell division 5.253922e-3
GO:0051726 regulation of cell cycle 5.261790e-3
GO:0046504 glycerol ether biosynthetic process 5.296863e-3
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity 5.306787e-3
GO:0043549 regulation of kinase activity 5.390671e-3
GO:0060745 mammary gland branching involved in pregnancy 5.401975e-3
GO:0060523 prostate epithelial cord elongation 5.401975e-3
GO:0042310 vasoconstriction 5.451202e-3
GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 5.519155e-3
GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis 5.519155e-3
GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 5.519155e-3
GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure 5.519155e-3
GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 5.519155e-3
GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 5.519155e-3
GO:0010625 positive regulation of Schwann cell proliferation 5.519155e-3
GO:2000055 positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 5.519155e-3
GO:0061310 canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development 5.519155e-3
GO:0071877 regulation of adrenergic receptor signaling pathway 5.519155e-3
GO:0090007 regulation of mitotic anaphase 5.519155e-3
GO:0001867 complement activation, lectin pathway 5.588589e-3
GO:0001990 regulation of systemic arterial blood pressure by hormone 5.608174e-3
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 5.621866e-3
GO:0007519 skeletal muscle tissue development 5.789944e-3
GO:0071241 cellular response to inorganic substance 5.830599e-3
GO:0002572 pro-T cell differentiation 5.880753e-3
GO:0014065 phosphatidylinositol 3-kinase cascade 5.891349e-3
GO:0070647 protein modification by small protein conjugation or removal 5.914602e-3
GO:0060736 prostate gland growth 5.963103e-3
GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process 5.986945e-3
GO:0043163 cell envelope organization 5.986945e-3
GO:0009415 response to water 6.026968e-3
GO:0021675 nerve development 6.056879e-3
GO:0008347 glial cell migration 6.183115e-3
GO:0072249 metanephric glomerular visceral epithelial cell development 6.183721e-3
GO:0048677 axon extension involved in regeneration 6.183721e-3
GO:0072274 metanephric glomerular basement membrane development 6.183721e-3
GO:0045769 negative regulation of asymmetric cell division 6.183721e-3
GO:0006742 NADP catabolic process 6.183721e-3
GO:0008285 negative regulation of cell proliferation 6.354256e-3
GO:0009743 response to carbohydrate stimulus 6.405839e-3
GO:0060839 endothelial cell fate commitment 6.441205e-3
GO:0000154 rRNA modification 6.496650e-3
GO:0006991 response to sterol depletion 6.496650e-3
GO:0043201 response to leucine 6.771330e-3
GO:0030823 regulation of cGMP metabolic process 6.858113e-3
GO:0046907 intracellular transport 6.868927e-3
GO:0008202 steroid metabolic process 6.899027e-3
GO:0043010 camera-type eye development 6.918969e-3
GO:0043408 regulation of MAPKKK cascade 7.039301e-3
GO:0060538 skeletal muscle organ development 7.048647e-3
GO:0002903 negative regulation of B cell apoptosis 7.112126e-3
GO:0006732 coenzyme metabolic process 7.157708e-3
GO:0016073 snRNA metabolic process 7.166802e-3
GO:2000611 positive regulation of thyroid hormone generation 7.186096e-3
GO:0061072 iris morphogenesis 7.186096e-3
GO:0051301 cell division 7.252641e-3
GO:0006563 L-serine metabolic process 7.304761e-3
GO:0009414 response to water deprivation 7.366111e-3
GO:0060836 lymphatic endothelial cell differentiation 7.393992e-3
GO:0010453 regulation of cell fate commitment 7.422858e-3
GO:0008206 bile acid metabolic process 7.516811e-3
GO:0010604 positive regulation of macromolecule metabolic process 7.587818e-3
GO:0050672 negative regulation of lymphocyte proliferation 7.592383e-3
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 7.742696e-3
GO:0000239 pachytene 7.795090e-3
GO:0006911 phagocytosis, engulfment 7.805515e-3
GO:0016192 vesicle-mediated transport 7.891011e-3
GO:0090245 axis elongation involved in somitogenesis 7.948827e-3
GO:0035519 protein K29-linked ubiquitination 7.948827e-3
GO:0021874 Wnt receptor signaling pathway involved in forebrain neuroblast division 7.948827e-3
GO:0010872 regulation of cholesterol esterification 8.093987e-3
GO:2000177 regulation of neural precursor cell proliferation 8.293502e-3
GO:0032277 negative regulation of gonadotropin secretion 8.418236e-3
GO:0046395 carboxylic acid catabolic process 8.445262e-3
GO:0050432 catecholamine secretion 8.456953e-3
GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 8.514495e-3
GO:0030335 positive regulation of cell migration 8.562473e-3
GO:0042093 T-helper cell differentiation 8.761945e-3
GO:0042537 benzene-containing compound metabolic process 8.763793e-3
GO:0007520 myoblast fusion 8.802881e-3
GO:0009725 response to hormone stimulus 8.835525e-3
GO:0048268 clathrin coat assembly 8.867346e-3
GO:0008209 androgen metabolic process 8.867743e-3
GO:0048646 anatomical structure formation involved in morphogenesis 9.000720e-3
GO:0000768 syncytium formation by plasma membrane fusion 9.204113e-3
GO:0019264 glycine biosynthetic process from serine 9.263579e-3
GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport 9.263579e-3
GO:0046325 negative regulation of glucose import 9.329843e-3
GO:2000147 positive regulation of cell motility 9.438584e-3
GO:0050868 negative regulation of T cell activation 9.467773e-3
GO:0032782 bile acid secretion 9.518678e-3
GO:0003096 renal sodium ion transport 9.518678e-3
GO:0010725 regulation of primitive erythrocyte differentiation 9.518678e-3
GO:0030890 positive regulation of B cell proliferation 9.615354e-3
GO:0071400 cellular response to oleic acid 9.629056e-3
GO:0009181 purine ribonucleoside diphosphate catabolic process 9.645248e-3
GO:0030850 prostate gland development 9.703279e-3
GO:0034622 cellular macromolecular complex assembly 9.725286e-3
GO:0043405 regulation of MAP kinase activity 9.745493e-3
GO:0060712 spongiotrophoblast layer development 9.791820e-3
GO:0030334 regulation of cell migration 9.793249e-3
GO:0070664 negative regulation of leukocyte proliferation 9.861727e-3
GO:0045636 positive regulation of melanocyte differentiation 9.861999e-3
GO:0007501 mesodermal cell fate specification 9.861999e-3
GO:0009888 tissue development 9.864570e-3
GO:2000106 regulation of leukocyte apoptosis 9.879432e-3
GO:0046463 acylglycerol biosynthetic process 9.892921e-3
GO:0006901 vesicle coating 9.946601e-3
GO:0000087 M phase of mitotic cell cycle 9.949952e-3
GO:0001656 metanephros development 9.986168e-3
GO:0009607 response to biotic stimulus 1.025194e-2
GO:0034383 low-density lipoprotein particle clearance 1.044251e-2
GO:0072144 glomerular mesangial cell development 1.046435e-2
GO:0060603 mammary gland duct morphogenesis 1.046658e-2
GO:0071577 zinc ion transmembrane transport 1.048432e-2
GO:0031122 cytoplasmic microtubule organization 1.048432e-2
GO:0070528 protein kinase C signaling cascade 1.049588e-2
GO:0045338 farnesyl diphosphate metabolic process 1.049588e-2
GO:0006269 DNA replication, synthesis of RNA primer 1.049588e-2
GO:0018342 protein prenylation 1.049588e-2
GO:0060788 ectodermal placode formation 1.060782e-2
GO:0045741 positive regulation of epidermal growth factor-activated receptor activity 1.065266e-2
GO:0006298 mismatch repair 1.066387e-2
GO:0032703 negative regulation of interleukin-2 production 1.066997e-2
GO:0060596 mammary placode formation 1.069175e-2
GO:0031529 ruffle organization 1.069175e-2
GO:0006725 cellular aromatic compound metabolic process 1.087637e-2
GO:0071702 organic substance transport 1.096462e-2
GO:0015840 urea transport 1.099406e-2
GO:0002691 regulation of cellular extravasation 1.099406e-2
GO:2000639 negative regulation of SREBP-mediated signaling pathway 1.106139e-2
GO:2000346 negative regulation of hepatocyte proliferation 1.106139e-2
GO:0048627 myoblast development 1.106139e-2
GO:0030826 regulation of cGMP biosynthetic process 1.118379e-2
GO:0044320 cellular response to leptin stimulus 1.118846e-2
GO:0061324 canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation 1.118846e-2
GO:0006413 translational initiation 1.119403e-2
GO:0042421 norepinephrine biosynthetic process 1.128201e-2
GO:0045737 positive regulation of cyclin-dependent protein kinase activity 1.140938e-2
GO:0007494 midgut development 1.140981e-2
GO:0006887 exocytosis 1.141227e-2
GO:0007126 meiosis 1.147841e-2
GO:0034441 plasma lipoprotein particle oxidation 1.149817e-2
GO:0042221 response to chemical stimulus 1.150060e-2
GO:0046496 nicotinamide nucleotide metabolic process 1.150483e-2
GO:0050688 regulation of defense response to virus 1.155242e-2
GO:0019220 regulation of phosphate metabolic process 1.161067e-2
GO:0051412 response to corticosterone stimulus 1.167377e-2
GO:0007569 cell aging 1.179443e-2
GO:0035067 negative regulation of histone acetylation 1.186750e-2
GO:0042180 cellular ketone metabolic process 1.201457e-2
GO:0007160 cell-matrix adhesion 1.212181e-2
GO:0055114 oxidation-reduction process 1.220730e-2
GO:0007141 male meiosis I 1.239446e-2
GO:0060914 heart formation 1.242752e-2
GO:0061098 positive regulation of protein tyrosine kinase activity 1.242876e-2
GO:0045576 mast cell activation 1.243372e-2
GO:0090280 positive regulation of calcium ion import 1.248157e-2
GO:0002669 positive regulation of T cell anergy 1.272685e-2
GO:0070527 platelet aggregation 1.293569e-2
GO:0009653 anatomical structure morphogenesis 1.295180e-2
GO:0042594 response to starvation 1.308889e-2
GO:0051409 response to nitrosative stress 1.312589e-2
GO:0018027 peptidyl-lysine dimethylation 1.312613e-2
GO:0046697 decidualization 1.312881e-2
GO:0010829 negative regulation of glucose transport 1.313660e-2
GO:0015810 aspartate transport 1.317705e-2
GO:0042176 regulation of protein catabolic process 1.329675e-2
GO:2001013 epithelial cell proliferation involve in renal tubule morphogenesis 1.349201e-2
GO:0072160 nephron tubule epithelial cell differentiation 1.349201e-2
GO:0061136 regulation of proteasomal protein catabolic process 1.352100e-2
GO:0015938 coenzyme A catabolic process 1.359230e-2
GO:0035106 operant conditioning 1.359230e-2
GO:0046464 acylglycerol catabolic process 1.377332e-2
GO:0001708 cell fate specification 1.390153e-2
GO:0042443 phenylethylamine metabolic process 1.408534e-2
GO:0033342 negative regulation of collagen binding 1.408534e-2
GO:0010571 positive regulation of DNA replication involved in S phase 1.408534e-2
GO:0015870 acetylcholine transport 1.408978e-2
GO:0051272 positive regulation of cellular component movement 1.409071e-2
GO:0030516 regulation of axon extension 1.412757e-2
GO:0048869 cellular developmental process 1.413096e-2
GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1.415252e-2
GO:0033315 meiotic cell cycle DNA replication checkpoint 1.423275e-2
GO:0031118 rRNA pseudouridine synthesis 1.423275e-2
GO:0000236 mitotic prometaphase 1.423275e-2
GO:0010032 meiotic chromosome condensation 1.423275e-2
GO:0001975 response to amphetamine 1.423888e-2
GO:0051338 regulation of transferase activity 1.439017e-2
GO:0032147 activation of protein kinase activity 1.443119e-2
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 1.445475e-2
GO:0043496 regulation of protein homodimerization activity 1.449380e-2
GO:0055015 ventricular cardiac muscle cell development 1.453688e-2
GO:0014070 response to organic cyclic compound 1.462250e-2
GO:0051216 cartilage development 1.475491e-2