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Novel motif:143

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name:motif143_ATGATGTG

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0032501 multicellular organismal process 2.876092e-23
GO:0050896 response to stimulus 3.975646e-23
GO:0050789 regulation of biological process 2.159674e-19
GO:0042221 response to chemical stimulus 2.165156e-18
GO:0065007 biological regulation 4.155481e-18
GO:0050794 regulation of cellular process 1.494410e-17
GO:0051716 cellular response to stimulus 2.079776e-17
GO:0007275 multicellular organismal development 7.409129e-17
GO:0050865 regulation of cell activation 4.207312e-16
GO:0032502 developmental process 2.094840e-15
GO:0048731 system development 1.256657e-14
GO:0007154 cell communication 1.601093e-14
GO:0048583 regulation of response to stimulus 2.221031e-14
GO:0015705 iodide transport 3.718639e-14
GO:0002694 regulation of leukocyte activation 5.537037e-14
GO:0048856 anatomical structure development 6.134219e-14
GO:0023052 signaling 5.570241e-13
GO:0051128 regulation of cellular component organization 6.278652e-13
GO:0032663 regulation of interleukin-2 production 6.510512e-13
GO:0051249 regulation of lymphocyte activation 7.849766e-13
GO:0023051 regulation of signaling 1.019053e-12
GO:0007165 signal transduction 1.582444e-12
GO:0065009 regulation of molecular function 3.530799e-12
GO:0006955 immune response 6.624077e-12
GO:0044281 small molecule metabolic process 1.189764e-11
GO:0051179 localization 1.370995e-11
GO:0002376 immune system process 1.525670e-11
GO:0050867 positive regulation of cell activation 1.679824e-11
GO:0048513 organ development 2.020357e-11
GO:0050863 regulation of T cell activation 2.133580e-11
GO:0051239 regulation of multicellular organismal process 4.866241e-11
GO:0065008 regulation of biological quality 5.548194e-11
GO:0010646 regulation of cell communication 5.605500e-11
GO:2000026 regulation of multicellular organismal development 6.968329e-11
GO:0050793 regulation of developmental process 1.464687e-10
GO:0006590 thyroid hormone generation 2.258646e-10
GO:0009966 regulation of signal transduction 2.357910e-10
GO:0045056 transcytosis 5.592783e-10
GO:0002696 positive regulation of leukocyte activation 6.003549e-10
GO:0006915 apoptosis 7.253216e-10
GO:0031641 regulation of myelination 1.184937e-9
GO:0012502 induction of programmed cell death 1.292653e-9
GO:0048518 positive regulation of biological process 1.484513e-9
GO:0006950 response to stress 1.647307e-9
GO:0012501 programmed cell death 1.867604e-9
GO:0007166 cell surface receptor linked signaling pathway 2.179594e-9
GO:0048522 positive regulation of cellular process 2.262487e-9
GO:0002682 regulation of immune system process 2.998554e-9
GO:0006917 induction of apoptosis 3.025782e-9
GO:0042445 hormone metabolic process 3.596517e-9
GO:0051960 regulation of nervous system development 4.443498e-9
GO:0042127 regulation of cell proliferation 5.892697e-9
GO:0006820 anion transport 6.295938e-9
GO:0006911 phagocytosis, engulfment 6.602887e-9
GO:0050790 regulation of catalytic activity 7.339973e-9
GO:0051336 regulation of hydrolase activity 7.367952e-9
GO:0008285 negative regulation of cell proliferation 7.690325e-9
GO:0051704 multi-organism process 7.887940e-9
GO:0032653 regulation of interleukin-10 production 8.312503e-9
GO:0042403 thyroid hormone metabolic process 9.164499e-9
GO:0048584 positive regulation of response to stimulus 1.284740e-8
GO:0002831 regulation of response to biotic stimulus 1.303865e-8
GO:0006508 proteolysis 1.411546e-8
GO:0050869 negative regulation of B cell activation 1.442505e-8
GO:0007608 sensory perception of smell 1.572649e-8
GO:0001817 regulation of cytokine production 1.693995e-8
GO:0050870 positive regulation of T cell activation 1.725666e-8
GO:0002676 regulation of chronic inflammatory response 1.774335e-8
GO:0010677 negative regulation of cellular carbohydrate metabolic process 1.848729e-8
GO:0043067 regulation of programmed cell death 2.130650e-8
GO:0016042 lipid catabolic process 2.145329e-8
GO:0006575 cellular modified amino acid metabolic process 2.159093e-8
GO:0051234 establishment of localization 2.939088e-8
GO:0007606 sensory perception of chemical stimulus 2.949884e-8
GO:0001775 cell activation 2.973999e-8
GO:0030168 platelet activation 3.506689e-8
GO:0042981 regulation of apoptosis 3.552520e-8
GO:0030836 positive regulation of actin filament depolymerization 3.619577e-8
GO:0021695 cerebellar cortex development 4.352021e-8
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity 4.460372e-8
GO:0044057 regulation of system process 4.882814e-8
GO:0042102 positive regulation of T cell proliferation 5.105840e-8
GO:0008202 steroid metabolic process 5.905210e-8
GO:0010817 regulation of hormone levels 6.687685e-8
GO:0006810 transport 6.746207e-8
GO:0008152 metabolic process 6.786136e-8
GO:0006897 endocytosis 7.169694e-8
GO:0042129 regulation of T cell proliferation 8.914431e-8
GO:0007399 nervous system development 9.011464e-8
GO:0045727 positive regulation of translation 9.070753e-8
GO:0023057 negative regulation of signaling 9.306732e-8
GO:0051246 regulation of protein metabolic process 9.982884e-8
GO:0010648 negative regulation of cell communication 1.006441e-7
GO:0007618 mating 1.081068e-7
GO:0021681 cerebellar granular layer development 1.089013e-7
GO:0051247 positive regulation of protein metabolic process 1.099073e-7
GO:0043243 positive regulation of protein complex disassembly 1.099425e-7
GO:0007155 cell adhesion 1.105886e-7
GO:0023056 positive regulation of signaling 1.114082e-7
GO:0006952 defense response 1.121747e-7
GO:0006066 alcohol metabolic process 1.127480e-7
GO:0009987 cellular process 1.130308e-7
GO:0016192 vesicle-mediated transport 1.358563e-7
GO:0002684 positive regulation of immune system process 1.361513e-7
GO:0008219 cell death 1.534977e-7
GO:0010647 positive regulation of cell communication 1.632580e-7
GO:0009056 catabolic process 1.803362e-7
GO:0051969 regulation of transmission of nerve impulse 1.804063e-7
GO:0030509 BMP signaling pathway 1.907569e-7
GO:0051251 positive regulation of lymphocyte activation 2.095552e-7
GO:0061024 membrane organization 2.151095e-7
GO:0048585 negative regulation of response to stimulus 2.200834e-7
GO:0030154 cell differentiation 2.295413e-7
GO:0071896 protein localization to adherens junction 2.706871e-7
GO:0009968 negative regulation of signal transduction 2.707747e-7
GO:0048468 cell development 2.780146e-7
GO:0048699 generation of neurons 3.207918e-7
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 3.333163e-7
GO:0016265 death 3.435995e-7
GO:0032400 melanosome localization 3.460013e-7
GO:0051240 positive regulation of multicellular organismal process 3.463168e-7
GO:0016044 cellular membrane organization 3.868813e-7
GO:0032673 regulation of interleukin-4 production 4.034156e-7
GO:2000345 regulation of hepatocyte proliferation 4.164776e-7
GO:0044106 cellular amine metabolic process 4.319369e-7
GO:0010941 regulation of cell death 4.319660e-7
GO:0048519 negative regulation of biological process 4.506823e-7
GO:0048869 cellular developmental process 4.727983e-7
GO:0021683 cerebellar granular layer morphogenesis 5.370952e-7
GO:0021758 putamen development 5.505156e-7
GO:0021757 caudate nucleus development 5.505156e-7
GO:0006922 cleavage of lamin 5.505156e-7
GO:0022008 neurogenesis 5.724072e-7
GO:0043068 positive regulation of programmed cell death 5.801412e-7
GO:0018958 phenol-containing compound metabolic process 5.856680e-7
GO:0034122 negative regulation of toll-like receptor signaling pathway 6.569708e-7
GO:0010033 response to organic substance 6.715926e-7
GO:0051875 pigment granule localization 6.732091e-7
GO:0009308 amine metabolic process 7.009564e-7
GO:0040011 locomotion 7.015678e-7
GO:0045619 regulation of lymphocyte differentiation 8.259656e-7
GO:0046034 ATP metabolic process 8.464864e-7
GO:0048523 negative regulation of cellular process 9.160294e-7
GO:0009611 response to wounding 9.299626e-7
GO:0019222 regulation of metabolic process 9.651455e-7
GO:0002769 natural killer cell inhibitory signaling pathway 1.078372e-6
GO:0018904 organic ether metabolic process 1.118226e-6
GO:0001818 negative regulation of cytokine production 1.132277e-6
GO:0021549 cerebellum development 1.170735e-6
GO:0050671 positive regulation of lymphocyte proliferation 1.220052e-6
GO:0050769 positive regulation of neurogenesis 1.239823e-6
GO:0042180 cellular ketone metabolic process 1.276690e-6
GO:0015698 inorganic anion transport 1.373670e-6
GO:0009628 response to abiotic stimulus 1.391181e-6
GO:0070663 regulation of leukocyte proliferation 1.414865e-6
GO:0019538 protein metabolic process 1.425675e-6
GO:0051640 organelle localization 1.427508e-6
GO:0006629 lipid metabolic process 1.562126e-6
GO:0051130 positive regulation of cellular component organization 1.572075e-6
GO:0043065 positive regulation of apoptosis 1.749808e-6
GO:0032733 positive regulation of interleukin-10 production 1.852650e-6
GO:0007320 insemination 1.951559e-6
GO:0050954 sensory perception of mechanical stimulus 2.002021e-6
GO:0071285 cellular response to lithium ion 2.036874e-6
GO:0050830 defense response to Gram-positive bacterium 2.133546e-6
GO:0006725 cellular aromatic compound metabolic process 2.139298e-6
GO:0042325 regulation of phosphorylation 2.238182e-6
GO:0032891 negative regulation of organic acid transport 2.308073e-6
GO:0006928 cellular component movement 2.383553e-6
GO:0006520 cellular amino acid metabolic process 2.384014e-6
GO:0044093 positive regulation of molecular function 2.413936e-6
GO:0009593 detection of chemical stimulus 2.633773e-6
GO:0045580 regulation of T cell differentiation 2.829177e-6
GO:0045595 regulation of cell differentiation 2.933016e-6
GO:0032743 positive regulation of interleukin-2 production 2.972213e-6
GO:0016043 cellular component organization 3.016387e-6
GO:0032268 regulation of cellular protein metabolic process 3.024136e-6
GO:0009967 positive regulation of signal transduction 3.242613e-6
GO:0021756 striatum development 3.295861e-6
GO:0032680 regulation of tumor necrosis factor production 3.365264e-6
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 3.394224e-6
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 3.485220e-6
GO:0002678 positive regulation of chronic inflammatory response 3.642825e-6
GO:0032844 regulation of homeostatic process 3.652457e-6
GO:0030182 neuron differentiation 3.717917e-6
GO:0009653 anatomical structure morphogenesis 3.838120e-6
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 3.890887e-6
GO:0045664 regulation of neuron differentiation 3.997894e-6
GO:0048732 gland development 4.076357e-6
GO:0032946 positive regulation of mononuclear cell proliferation 4.086408e-6
GO:0046503 glycerolipid catabolic process 4.135648e-6
GO:0007605 sensory perception of sound 4.188400e-6
GO:0030510 regulation of BMP signaling pathway 4.321730e-6
GO:0007088 regulation of mitosis 4.433290e-6
GO:0007015 actin filament organization 4.447816e-6
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 4.462235e-6
GO:0042537 benzene-containing compound metabolic process 4.851704e-6
GO:0045069 regulation of viral genome replication 4.889336e-6
GO:0010866 regulation of triglyceride biosynthetic process 4.922669e-6
GO:0019220 regulation of phosphate metabolic process 5.203846e-6
GO:0044248 cellular catabolic process 5.213628e-6
GO:0022414 reproductive process 5.225324e-6
GO:0043900 regulation of multi-organism process 5.353554e-6
GO:0019752 carboxylic acid metabolic process 5.386104e-6
GO:0009893 positive regulation of metabolic process 5.708320e-6
GO:0051345 positive regulation of hydrolase activity 6.291079e-6
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway 6.327421e-6
GO:0031644 regulation of neurological system process 6.334599e-6
GO:0060284 regulation of cell development 6.689174e-6
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 6.698726e-6
GO:0050767 regulation of neurogenesis 7.206242e-6
GO:0032101 regulation of response to external stimulus 7.396408e-6
GO:0051726 regulation of cell cycle 7.665470e-6
GO:0046464 acylglycerol catabolic process 7.906835e-6
GO:0007599 hemostasis 7.935536e-6
GO:0033363 secretory granule organization 7.954481e-6
GO:0031399 regulation of protein modification process 8.043507e-6
GO:0006662 glycerol ether metabolic process 8.407972e-6
GO:0043255 regulation of carbohydrate biosynthetic process 8.439617e-6
GO:0021528 commissural neuron differentiation in spinal cord 8.456817e-6
GO:0010942 positive regulation of cell death 8.693348e-6
GO:0032536 regulation of cell projection size 8.795704e-6
GO:0000003 reproduction 8.867914e-6
GO:0080134 regulation of response to stress 8.895320e-6
GO:0009605 response to external stimulus 9.036312e-6
GO:0006811 ion transport 9.371486e-6
GO:0071840 cellular component organization or biogenesis 9.478373e-6
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 9.605093e-6
GO:0032649 regulation of interferon-gamma production 9.636621e-6
GO:0002683 negative regulation of immune system process 9.655223e-6
GO:0010557 positive regulation of macromolecule biosynthetic process 1.023000e-5
GO:0070665 positive regulation of leukocyte proliferation 1.042142e-5
GO:0034143 regulation of toll-like receptor 4 signaling pathway 1.085475e-5
GO:0031328 positive regulation of cellular biosynthetic process 1.085669e-5
GO:0051956 negative regulation of amino acid transport 1.094234e-5
GO:0006448 regulation of translational elongation 1.094234e-5
GO:0061031 endodermal digestive tract morphogenesis 1.122004e-5
GO:0019836 hemolysis by symbiont of host erythrocytes 1.130944e-5
GO:0010757 negative regulation of plasminogen activation 1.155281e-5
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 1.168171e-5
GO:0050670 regulation of lymphocyte proliferation 1.203101e-5
GO:0001932 regulation of protein phosphorylation 1.230361e-5
GO:0007596 blood coagulation 1.243195e-5
GO:0003006 developmental process involved in reproduction 1.253027e-5
GO:0045786 negative regulation of cell cycle 1.303841e-5
GO:0010769 regulation of cell morphogenesis involved in differentiation 1.317674e-5
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 1.339884e-5
GO:0034135 regulation of toll-like receptor 2 signaling pathway 1.354397e-5
GO:0030574 collagen catabolic process 1.364557e-5
GO:0031325 positive regulation of cellular metabolic process 1.387914e-5
GO:0010035 response to inorganic substance 1.444997e-5
GO:0031323 regulation of cellular metabolic process 1.450616e-5
GO:0051606 detection of stimulus 1.485181e-5
GO:0051707 response to other organism 1.550325e-5
GO:0051648 vesicle localization 1.584442e-5
GO:0006082 organic acid metabolic process 1.635262e-5
GO:0010720 positive regulation of cell development 1.650153e-5
GO:0006109 regulation of carbohydrate metabolic process 1.668289e-5
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 1.677137e-5
GO:0007620 copulation 1.708031e-5
GO:0009891 positive regulation of biosynthetic process 1.714969e-5
GO:0007638 mechanosensory behavior 1.835097e-5
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 1.873957e-5
GO:0010638 positive regulation of organelle organization 1.885931e-5
GO:0002037 negative regulation of L-glutamate transport 1.933099e-5
GO:0045994 positive regulation of translational initiation by iron 1.933099e-5
GO:0035871 protein K11-linked deubiquitination 2.057761e-5
GO:0051877 pigment granule aggregation in cell center 2.063060e-5
GO:0080090 regulation of primary metabolic process 2.077518e-5
GO:0009201 ribonucleoside triphosphate biosynthetic process 2.084824e-5
GO:0044243 multicellular organismal catabolic process 2.139822e-5
GO:0060740 prostate gland epithelium morphogenesis 2.251172e-5
GO:0022604 regulation of cell morphogenesis 2.275033e-5
GO:0060512 prostate gland morphogenesis 2.293755e-5
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 2.346607e-5
GO:0006417 regulation of translation 2.350286e-5
GO:0035094 response to nicotine 2.467265e-5
GO:0052547 regulation of peptidase activity 2.533540e-5
GO:0044238 primary metabolic process 2.539395e-5
GO:0045076 regulation of interleukin-2 biosynthetic process 2.539696e-5
GO:0008624 induction of apoptosis by extracellular signals 2.583243e-5
GO:0048608 reproductive structure development 2.615259e-5
GO:0010675 regulation of cellular carbohydrate metabolic process 2.625018e-5
GO:0050852 T cell receptor signaling pathway 2.663035e-5
GO:0009617 response to bacterium 2.744281e-5
GO:0046032 ADP catabolic process 2.876897e-5
GO:0046709 IDP catabolic process 2.876897e-5
GO:0042060 wound healing 2.883536e-5
GO:0022603 regulation of anatomical structure morphogenesis 2.941625e-5
GO:0070670 response to interleukin-4 2.971515e-5
GO:0032944 regulation of mononuclear cell proliferation 3.022707e-5
GO:0030878 thyroid gland development 3.165855e-5
GO:0009268 response to pH 3.170399e-5
GO:0010608 posttranscriptional regulation of gene expression 3.195055e-5
GO:0033135 regulation of peptidyl-serine phosphorylation 3.297258e-5
GO:0031214 biomineral tissue development 3.322467e-5
GO:2000021 regulation of ion homeostasis 3.340515e-5
GO:0031223 auditory behavior 3.369532e-5
GO:0009607 response to biotic stimulus 3.434546e-5
GO:0032713 negative regulation of interleukin-4 production 3.556525e-5
GO:0051574 positive regulation of histone H3-K9 methylation 3.661798e-5
GO:0044092 negative regulation of molecular function 3.677324e-5
GO:0090207 regulation of triglyceride metabolic process 3.687948e-5
GO:2000116 regulation of cysteine-type endopeptidase activity 3.704225e-5
GO:0045597 positive regulation of cell differentiation 3.860373e-5
GO:0008207 C21-steroid hormone metabolic process 3.893540e-5
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 3.927232e-5
GO:0019433 triglyceride catabolic process 3.933127e-5
GO:0044242 cellular lipid catabolic process 3.951656e-5
GO:0034612 response to tumor necrosis factor 3.961333e-5
GO:0032401 establishment of melanosome localization 4.030939e-5
GO:0010604 positive regulation of macromolecule metabolic process 4.095822e-5
GO:0050878 regulation of body fluid levels 4.153600e-5
GO:0055086 nucleobase-containing small molecule metabolic process 4.174432e-5
GO:0002819 regulation of adaptive immune response 4.199412e-5
GO:0010038 response to metal ion 4.220187e-5
GO:0071675 regulation of mononuclear cell migration 4.343743e-5
GO:0010755 regulation of plasminogen activation 4.379568e-5
GO:0008347 glial cell migration 4.447055e-5
GO:0048666 neuron development 4.517412e-5
GO:0032049 cardiolipin biosynthetic process 4.756705e-5
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter 5.247710e-5
GO:0050849 negative regulation of calcium-mediated signaling 5.313446e-5
GO:0050776 regulation of immune response 5.327259e-5
GO:0032656 regulation of interleukin-13 production 5.339486e-5
GO:0032703 negative regulation of interleukin-2 production 5.346968e-5
GO:0002697 regulation of immune effector process 5.408529e-5
GO:0055088 lipid homeostasis 5.444691e-5
GO:0016119 carotene metabolic process 5.493140e-5
GO:0021544 subpallium development 5.541678e-5
GO:0002839 positive regulation of immune response to tumor cell 5.577169e-5
GO:0046637 regulation of alpha-beta T cell differentiation 5.729985e-5
GO:0002237 response to molecule of bacterial origin 5.749376e-5
GO:0003008 system process 5.922872e-5
GO:0010759 positive regulation of macrophage chemotaxis 5.963444e-5
GO:0051250 negative regulation of lymphocyte activation 6.003543e-5
GO:0048745 smooth muscle tissue development 6.011292e-5
GO:0043547 positive regulation of GTPase activity 6.254295e-5
GO:0002082 regulation of oxidative phosphorylation 6.295313e-5
GO:0044087 regulation of cellular component biogenesis 6.360660e-5
GO:0030513 positive regulation of BMP signaling pathway 6.498561e-5
GO:0030728 ovulation 6.502000e-5
GO:0009142 nucleoside triphosphate biosynthetic process 6.514365e-5
GO:2000352 negative regulation of endothelial cell apoptosis 6.617867e-5
GO:0010719 negative regulation of epithelial to mesenchymal transition 6.617867e-5
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 6.840590e-5
GO:0051905 establishment of pigment granule localization 6.853911e-5
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 6.861850e-5
GO:0051056 regulation of small GTPase mediated signal transduction 6.950599e-5
GO:0008050 female courtship behavior 7.038997e-5
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 7.038997e-5
GO:0043244 regulation of protein complex disassembly 7.138699e-5
GO:0060743 epithelial cell maturation involved in prostate gland development 7.157948e-5
GO:0032270 positive regulation of cellular protein metabolic process 7.249020e-5
GO:0045494 photoreceptor cell maintenance 7.727019e-5
GO:0021696 cerebellar cortex morphogenesis 7.731741e-5
GO:0034139 regulation of toll-like receptor 3 signaling pathway 7.760755e-5
GO:0006595 polyamine metabolic process 8.051023e-5
GO:0008284 positive regulation of cell proliferation 8.127844e-5
GO:0002576 platelet degranulation 8.173064e-5
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 8.301837e-5
GO:0007176 regulation of epidermal growth factor-activated receptor activity 8.471348e-5
GO:0022037 metencephalon development 8.497858e-5
GO:0042058 regulation of epidermal growth factor receptor signaling pathway 8.758392e-5
GO:0050778 positive regulation of immune response 9.199076e-5
GO:0070560 protein secretion by platelet 9.238189e-5
GO:0060305 regulation of cell diameter 9.238189e-5
GO:0010920 negative regulation of inositol phosphate biosynthetic process 9.238189e-5
GO:0010925 positive regulation of inositol-polyphosphate 5-phosphatase activity 9.238189e-5
GO:0030845 inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway 9.238189e-5
GO:0009894 regulation of catabolic process 9.387215e-5
GO:0045621 positive regulation of lymphocyte differentiation 9.617979e-5
GO:0032496 response to lipopolysaccharide 9.696962e-5
GO:0033121 regulation of purine nucleotide catabolic process 9.960852e-5
GO:0042108 positive regulation of cytokine biosynthetic process 1.007225e-4
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.022908e-4
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 1.023882e-4
GO:0034121 regulation of toll-like receptor signaling pathway 1.023882e-4
GO:0046007 negative regulation of activated T cell proliferation 1.042153e-4
GO:0010758 regulation of macrophage chemotaxis 1.042962e-4
GO:0030101 natural killer cell activation 1.052464e-4
GO:0002286 T cell activation involved in immune response 1.052464e-4
GO:0033036 macromolecule localization 1.058850e-4
GO:0071295 cellular response to vitamin 1.103239e-4
GO:0003166 bundle of His development 1.131878e-4
GO:0060741 prostate gland stromal morphogenesis 1.156421e-4
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 1.164082e-4
GO:0032233 positive regulation of actin filament bundle assembly 1.181707e-4
GO:0046634 regulation of alpha-beta T cell activation 1.184748e-4
GO:0070536 protein K63-linked deubiquitination 1.188020e-4
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.206144e-4
GO:0060291 long-term synaptic potentiation 1.238043e-4
GO:0055067 monovalent inorganic cation homeostasis 1.259977e-4
GO:0046325 negative regulation of glucose import 1.263931e-4
GO:0032494 response to peptidoglycan 1.271818e-4
GO:0051495 positive regulation of cytoskeleton organization 1.274414e-4
GO:0009145 purine nucleoside triphosphate biosynthetic process 1.275105e-4
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 1.278276e-4
GO:0045123 cellular extravasation 1.283446e-4
GO:0050760 negative regulation of thymidylate synthase biosynthetic process 1.283487e-4
GO:0002077 acrosome matrix dispersal 1.283487e-4
GO:0006447 regulation of translational initiation by iron 1.285031e-4
GO:0006754 ATP biosynthetic process 1.314184e-4
GO:0048711 positive regulation of astrocyte differentiation 1.325172e-4
GO:0021680 cerebellar Purkinje cell layer development 1.325172e-4
GO:0016125 sterol metabolic process 1.364936e-4
GO:0021707 cerebellar granule cell differentiation 1.367373e-4
GO:0071622 regulation of granulocyte chemotaxis 1.367687e-4
GO:0051656 establishment of organelle localization 1.378390e-4
GO:0045777 positive regulation of blood pressure 1.409152e-4
GO:0010529 negative regulation of transposition 1.438099e-4
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 1.449169e-4
GO:0044356 clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine 1.472521e-4
GO:0042466 chemokinesis 1.472521e-4
GO:0045082 positive regulation of interleukin-10 biosynthetic process 1.520201e-4
GO:0048241 epinephrine transport 1.527063e-4
GO:0048011 nerve growth factor receptor signaling pathway 1.591163e-4
GO:2000347 positive regulation of hepatocyte proliferation 1.602705e-4
GO:0090291 negative regulation of osteoclast proliferation 1.602705e-4
GO:2000349 negative regulation of CD40 signaling pathway 1.602705e-4
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 1.602705e-4
GO:0072573 tolerance induction to lipopolysaccharide 1.602705e-4
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.602705e-4
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.602705e-4
GO:0022600 digestive system process 1.612843e-4
GO:0008625 induction of apoptosis via death domain receptors 1.630527e-4
GO:0000413 protein peptidyl-prolyl isomerization 1.638368e-4
GO:0048870 cell motility 1.644838e-4
GO:0051897 positive regulation of protein kinase B signaling cascade 1.649277e-4
GO:0043046 DNA methylation involved in gamete generation 1.652781e-4
GO:0050882 voluntary musculoskeletal movement 1.653995e-4
GO:0021860 pyramidal neuron development 1.653995e-4
GO:0001960 negative regulation of cytokine-mediated signaling pathway 1.665547e-4
GO:0042534 regulation of tumor necrosis factor biosynthetic process 1.680902e-4
GO:0045787 positive regulation of cell cycle 1.703369e-4
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 1.717240e-4
GO:0030644 cellular chloride ion homeostasis 1.719236e-4
GO:0006909 phagocytosis 1.767742e-4
GO:0001539 ciliary or flagellar motility 1.772780e-4
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 1.795024e-4
GO:0034587 piRNA metabolic process 1.802008e-4
GO:0031670 cellular response to nutrient 1.837090e-4
GO:0042035 regulation of cytokine biosynthetic process 1.840791e-4
GO:0070887 cellular response to chemical stimulus 1.886321e-4
GO:0046635 positive regulation of alpha-beta T cell activation 1.886926e-4
GO:0007346 regulation of mitotic cell cycle 1.969221e-4
GO:0002064 epithelial cell development 1.980437e-4
GO:2000639 negative regulation of SREBP-mediated signaling pathway 1.994371e-4
GO:2000346 negative regulation of hepatocyte proliferation 1.994371e-4
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 1.995919e-4
GO:0008203 cholesterol metabolic process 2.045736e-4
GO:0072334 UDP-galactose transmembrane transport 2.080257e-4
GO:0045161 neuronal ion channel clustering 2.110419e-4
GO:0090324 negative regulation of oxidative phosphorylation 2.119096e-4
GO:0010255 glucose mediated signaling pathway 2.119096e-4
GO:0010717 regulation of epithelial to mesenchymal transition 2.150238e-4
GO:0008206 bile acid metabolic process 2.162039e-4
GO:0070527 platelet aggregation 2.191704e-4
GO:0051798 positive regulation of hair follicle development 2.197643e-4
GO:0048167 regulation of synaptic plasticity 2.218707e-4
GO:0042446 hormone biosynthetic process 2.227515e-4
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.237976e-4
GO:0007167 enzyme linked receptor protein signaling pathway 2.260459e-4
GO:0014047 glutamate secretion 2.272013e-4
GO:0030198 extracellular matrix organization 2.287585e-4
GO:0048667 cell morphogenesis involved in neuron differentiation 2.334505e-4
GO:0051971 positive regulation of transmission of nerve impulse 2.360516e-4
GO:0010466 negative regulation of peptidase activity 2.363463e-4
GO:0045900 negative regulation of translational elongation 2.435903e-4
GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development 2.448854e-4
GO:0006766 vitamin metabolic process 2.454656e-4
GO:0046887 positive regulation of hormone secretion 2.483844e-4
GO:0051346 negative regulation of hydrolase activity 2.505403e-4
GO:0010812 negative regulation of cell-substrate adhesion 2.510303e-4
GO:0006887 exocytosis 2.544108e-4
GO:0071299 cellular response to vitamin A 2.566826e-4
GO:0015949 nucleobase-containing small molecule interconversion 2.669456e-4
GO:0048589 developmental growth 2.673901e-4
GO:0002708 positive regulation of lymphocyte mediated immunity 2.686743e-4
GO:0002793 positive regulation of peptide secretion 2.708139e-4
GO:0031060 regulation of histone methylation 2.711379e-4
GO:0002891 positive regulation of immunoglobulin mediated immune response 2.745724e-4
GO:0071300 cellular response to retinoic acid 2.751264e-4
GO:0002036 regulation of L-glutamate transport 2.784623e-4
GO:0001819 positive regulation of cytokine production 2.808680e-4
GO:0045071 negative regulation of viral genome replication 2.817870e-4
GO:0090277 positive regulation of peptide hormone secretion 2.912939e-4
GO:0055114 oxidation-reduction process 2.917455e-4
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 2.923181e-4
GO:0033043 regulation of organelle organization 2.949975e-4
GO:0035058 nonmotile primary cilium assembly 2.986843e-4
GO:0046851 negative regulation of bone remodeling 2.992354e-4
GO:0030030 cell projection organization 3.012120e-4
GO:0046638 positive regulation of alpha-beta T cell differentiation 3.031828e-4
GO:0044236 multicellular organismal metabolic process 3.044720e-4
GO:0072358 cardiovascular system development 3.075018e-4
GO:0002765 immune response-inhibiting signal transduction 3.129023e-4
GO:0071356 cellular response to tumor necrosis factor 3.139200e-4
GO:0044271 cellular nitrogen compound biosynthetic process 3.170514e-4
GO:0061041 regulation of wound healing 3.213415e-4


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0050896 response to stimulus 5.819917e-18
GO:0007154 cell communication 3.037573e-14
GO:0048583 regulation of response to stimulus 3.762877e-13
GO:0002673 regulation of acute inflammatory response 4.122581e-13
GO:0050870 positive regulation of T cell activation 7.315863e-13
GO:0016125 sterol metabolic process 1.814493e-12
GO:0016126 sterol biosynthetic process 1.919468e-12
GO:0051347 positive regulation of transferase activity 1.488039e-11
GO:0007165 signal transduction 2.075223e-11
GO:0008203 cholesterol metabolic process 4.212432e-11
GO:0032964 collagen biosynthetic process 5.784313e-11
GO:0023052 signaling 6.253042e-11
GO:0030199 collagen fibril organization 1.186250e-10
GO:0034505 tooth mineralization 1.264846e-10
GO:0006695 cholesterol biosynthetic process 1.616376e-10
GO:0033674 positive regulation of kinase activity 2.613338e-10
GO:0002920 regulation of humoral immune response 3.133848e-10
GO:0030036 actin cytoskeleton organization 3.254899e-10
GO:0006694 steroid biosynthetic process 3.263611e-10
GO:0045582 positive regulation of T cell differentiation 3.430843e-10
GO:0045860 positive regulation of protein kinase activity 3.581592e-10
GO:0019216 regulation of lipid metabolic process 5.751818e-10
GO:0051056 regulation of small GTPase mediated signal transduction 8.548613e-10
GO:0002922 positive regulation of humoral immune response 1.130282e-9
GO:0030029 actin filament-based process 1.402174e-9
GO:0032369 negative regulation of lipid transport 1.688000e-9
GO:0070613 regulation of protein processing 1.793931e-9
GO:0045621 positive regulation of lymphocyte differentiation 1.918432e-9
GO:0009966 regulation of signal transduction 2.073541e-9
GO:0051716 cellular response to stimulus 2.585615e-9
GO:0032375 negative regulation of cholesterol transport 2.718348e-9
GO:0002682 regulation of immune system process 3.359642e-9
GO:0002708 positive regulation of lymphocyte mediated immunity 3.982322e-9
GO:0050863 regulation of T cell activation 4.005814e-9
GO:0007155 cell adhesion 4.803320e-9
GO:0071229 cellular response to acid 5.302684e-9
GO:0071230 cellular response to amino acid stimulus 6.585905e-9
GO:0050776 regulation of immune response 6.617461e-9
GO:0031960 response to corticosteroid stimulus 8.383107e-9
GO:0050790 regulation of catalytic activity 8.578296e-9
GO:0002675 positive regulation of acute inflammatory response 8.958145e-9
GO:0022610 biological adhesion 9.036504e-9
GO:0000187 activation of MAPK activity 9.380111e-9
GO:0050727 regulation of inflammatory response 1.060431e-8
GO:0007010 cytoskeleton organization 1.340450e-8
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.396539e-8
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.660891e-8
GO:0043085 positive regulation of catalytic activity 2.120547e-8
GO:0023051 regulation of signaling 2.974751e-8
GO:0010985 negative regulation of lipoprotein particle clearance 3.247269e-8
GO:0006707 cholesterol catabolic process 3.715685e-8
GO:0044093 positive regulation of molecular function 3.726185e-8
GO:0002685 regulation of leukocyte migration 4.452538e-8
GO:0045580 regulation of T cell differentiation 4.497181e-8
GO:0006952 defense response 5.030478e-8
GO:0051005 negative regulation of lipoprotein lipase activity 5.111506e-8
GO:0034382 chylomicron remnant clearance 5.111506e-8
GO:0031347 regulation of defense response 5.433359e-8
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 6.464124e-8
GO:0045859 regulation of protein kinase activity 8.441305e-8
GO:0002696 positive regulation of leukocyte activation 1.183198e-7
GO:0071418 cellular response to amine stimulus 1.208492e-7
GO:0001932 regulation of protein phosphorylation 1.219687e-7
GO:0051338 regulation of transferase activity 1.252406e-7
GO:2000309 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production 1.297771e-7
GO:0030449 regulation of complement activation 1.307010e-7
GO:0042221 response to chemical stimulus 1.377718e-7
GO:0019218 regulation of steroid metabolic process 1.493785e-7
GO:0031532 actin cytoskeleton reorganization 1.645881e-7
GO:0007015 actin filament organization 1.688047e-7
GO:0007166 cell surface receptor linked signaling pathway 1.991621e-7
GO:0050778 positive regulation of immune response 2.103205e-7
GO:0008202 steroid metabolic process 2.139790e-7
GO:0010984 regulation of lipoprotein particle clearance 2.246514e-7
GO:0071417 cellular response to organic nitrogen 2.253460e-7
GO:0045940 positive regulation of steroid metabolic process 2.411854e-7
GO:0043549 regulation of kinase activity 2.445246e-7
GO:0090209 negative regulation of triglyceride metabolic process 2.588783e-7
GO:0051240 positive regulation of multicellular organismal process 2.593239e-7
GO:0048261 negative regulation of receptor-mediated endocytosis 2.785006e-7
GO:0010954 positive regulation of protein processing 2.803132e-7
GO:0046890 regulation of lipid biosynthetic process 2.907588e-7
GO:0050995 negative regulation of lipid catabolic process 2.972212e-7
GO:0045717 negative regulation of fatty acid biosynthetic process 3.282647e-7
GO:0035023 regulation of Rho protein signal transduction 3.410424e-7
GO:0019098 reproductive behavior 3.788613e-7
GO:0001970 positive regulation of activation of membrane attack complex 3.802746e-7
GO:0060346 bone trabecula formation 3.918438e-7
GO:0045619 regulation of lymphocyte differentiation 4.215685e-7
GO:0050706 regulation of interleukin-1 beta secretion 4.306199e-7
GO:0050954 sensory perception of mechanical stimulus 4.357200e-7
GO:0042102 positive regulation of T cell proliferation 4.442020e-7
GO:0046314 phosphocreatine biosynthetic process 4.501777e-7
GO:0002684 positive regulation of immune system process 4.572344e-7
GO:0010987 negative regulation of high-density lipoprotein particle clearance 4.714846e-7
GO:0010897 negative regulation of triglyceride catabolic process 4.714846e-7
GO:0045922 negative regulation of fatty acid metabolic process 5.078836e-7
GO:0050867 positive regulation of cell activation 5.143559e-7
GO:0032501 multicellular organismal process 5.371383e-7
GO:0051251 positive regulation of lymphocyte activation 5.945730e-7
GO:0071902 positive regulation of protein serine/threonine kinase activity 5.996045e-7
GO:0051094 positive regulation of developmental process 6.106430e-7
GO:0050821 protein stabilization 6.277598e-7
GO:0032078 negative regulation of endodeoxyribonuclease activity 6.785999e-7
GO:0006922 cleavage of lamin 6.785999e-7
GO:0007600 sensory perception 6.881679e-7
GO:0001967 suckling behavior 7.261733e-7
GO:0043406 positive regulation of MAP kinase activity 7.742039e-7
GO:0070208 protein heterotrimerization 7.909037e-7
GO:0016042 lipid catabolic process 8.448912e-7
GO:0022600 digestive system process 1.014502e-6
GO:0065009 regulation of molecular function 1.037830e-6
GO:0014075 response to amine stimulus 1.180566e-6
GO:0001957 intramembranous ossification 1.182840e-6
GO:0050810 regulation of steroid biosynthetic process 1.183021e-6
GO:0002740 negative regulation of cytokine secretion involved in immune response 1.314769e-6
GO:0035094 response to nicotine 1.405610e-6
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 1.413486e-6
GO:0050704 regulation of interleukin-1 secretion 1.416801e-6
GO:0010033 response to organic substance 1.454219e-6
GO:0048856 anatomical structure development 1.458818e-6
GO:0001969 regulation of activation of membrane attack complex 1.479355e-6
GO:0007352 zygotic specification of dorsal/ventral axis 1.591250e-6
GO:0070508 cholesterol import 1.653697e-6
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.746173e-6
GO:0019220 regulation of phosphate metabolic process 1.865066e-6
GO:2000639 negative regulation of SREBP-mediated signaling pathway 1.883117e-6
GO:2000346 negative regulation of hepatocyte proliferation 1.883117e-6
GO:2000273 positive regulation of receptor activity 1.984156e-6
GO:0010749 regulation of nitric oxide mediated signal transduction 2.054629e-6
GO:0010989 negative regulation of low-density lipoprotein particle clearance 2.054629e-6
GO:0002885 positive regulation of hypersensitivity 2.079574e-6
GO:0042325 regulation of phosphorylation 2.225656e-6
GO:0002861 regulation of inflammatory response to antigenic stimulus 2.234684e-6
GO:0032101 regulation of response to external stimulus 2.351800e-6
GO:0002694 regulation of leukocyte activation 2.368757e-6
GO:0045834 positive regulation of lipid metabolic process 2.419621e-6
GO:0050707 regulation of cytokine secretion 2.528470e-6
GO:0045597 positive regulation of cell differentiation 2.538496e-6
GO:0002821 positive regulation of adaptive immune response 2.593000e-6
GO:0048731 system development 2.598545e-6
GO:0032879 regulation of localization 2.909178e-6
GO:0002577 regulation of antigen processing and presentation 2.921335e-6
GO:0010893 positive regulation of steroid biosynthetic process 2.952077e-6
GO:0034441 plasma lipoprotein particle oxidation 2.959620e-6
GO:0032963 collagen metabolic process 3.027877e-6
GO:0043589 skin morphogenesis 3.081186e-6
GO:0045931 positive regulation of mitotic cell cycle 3.090004e-6
GO:0051336 regulation of hydrolase activity 3.183127e-6
GO:0046634 regulation of alpha-beta T cell activation 3.394061e-6
GO:0002688 regulation of leukocyte chemotaxis 3.413933e-6
GO:0007179 transforming growth factor beta receptor signaling pathway 3.549865e-6
GO:0006468 protein phosphorylation 3.555927e-6
GO:0031620 regulation of fever generation 3.558332e-6
GO:0031214 biomineral tissue development 3.658131e-6
GO:0051917 regulation of fibrinolysis 3.726340e-6
GO:0043200 response to amino acid stimulus 3.916497e-6
GO:0060558 regulation of calcidiol 1-monooxygenase activity 3.916971e-6
GO:0007605 sensory perception of sound 4.022999e-6
GO:0050865 regulation of cell activation 4.061317e-6
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 4.315086e-6
GO:0060192 negative regulation of lipase activity 4.669009e-6
GO:0046578 regulation of Ras protein signal transduction 4.737413e-6
GO:0061383 trabecula morphogenesis 4.969497e-6
GO:0048513 organ development 5.264061e-6
GO:0043652 engulfment of apoptotic cell 5.319043e-6
GO:0060557 positive regulation of vitamin D biosynthetic process 5.361744e-6
GO:0007275 multicellular organismal development 5.498853e-6
GO:0007176 regulation of epidermal growth factor-activated receptor activity 5.854813e-6
GO:0002687 positive regulation of leukocyte migration 5.924893e-6
GO:0042345 regulation of NF-kappaB import into nucleus 6.155514e-6
GO:0035272 exocrine system development 6.193272e-6
GO:0010754 negative regulation of cGMP-mediated signaling 6.441570e-6
GO:0030967 ER-nuclear sterol response pathway 6.441570e-6
GO:0010982 regulation of high-density lipoprotein particle clearance 6.441570e-6
GO:0010751 negative regulation of nitric oxide mediated signal transduction 6.441570e-6
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 6.441570e-6
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 6.441570e-6
GO:0035419 activation of MAPK activity involved in innate immune response 6.726430e-6
GO:0008588 release of cytoplasmic sequestered NF-kappaB 6.756227e-6
GO:0051384 response to glucocorticoid stimulus 6.871255e-6
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7.566738e-6
GO:0048251 elastic fiber assembly 8.552255e-6
GO:0042129 regulation of T cell proliferation 9.013421e-6
GO:0070848 response to growth factor stimulus 9.208912e-6
GO:0006991 response to sterol depletion 9.515788e-6
GO:0051918 negative regulation of fibrinolysis 9.817408e-6
GO:0009628 response to abiotic stimulus 9.825048e-6
GO:0050974 detection of mechanical stimulus involved in sensory perception 9.862365e-6
GO:0002238 response to molecule of fungal origin 1.016837e-5
GO:0032861 activation of Rap GTPase activity 1.048951e-5
GO:0071363 cellular response to growth factor stimulus 1.108352e-5
GO:0050709 negative regulation of protein secretion 1.119947e-5
GO:0018149 peptide cross-linking 1.138583e-5
GO:0040018 positive regulation of multicellular organism growth 1.149800e-5
GO:0009101 glycoprotein biosynthetic process 1.152185e-5
GO:0050973 detection of mechanical stimulus involved in equilibrioception 1.166973e-5
GO:0002683 negative regulation of immune system process 1.174167e-5
GO:0002706 regulation of lymphocyte mediated immunity 1.212024e-5
GO:0008211 glucocorticoid metabolic process 1.231870e-5
GO:0042157 lipoprotein metabolic process 1.233510e-5
GO:0044259 multicellular organismal macromolecule metabolic process 1.332744e-5
GO:0032103 positive regulation of response to external stimulus 1.403676e-5
GO:0048545 response to steroid hormone stimulus 1.448952e-5
GO:0051272 positive regulation of cellular component movement 1.462704e-5
GO:0060621 negative regulation of cholesterol import 1.640627e-5
GO:0090030 regulation of steroid hormone biosynthetic process 1.691558e-5
GO:0006950 response to stress 1.694381e-5
GO:0046638 positive regulation of alpha-beta T cell differentiation 1.698517e-5
GO:0006796 phosphate-containing compound metabolic process 1.717076e-5
GO:0032502 developmental process 1.836104e-5
GO:0071594 thymocyte aggregation 1.839167e-5
GO:0070887 cellular response to chemical stimulus 1.847588e-5
GO:0006066 alcohol metabolic process 2.026207e-5
GO:0001817 regulation of cytokine production 2.126531e-5
GO:0050713 negative regulation of interleukin-1 beta secretion 2.127026e-5
GO:0031645 negative regulation of neurological system process 2.198940e-5
GO:0032147 activation of protein kinase activity 2.227007e-5
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 2.380302e-5
GO:0046373 L-arabinose metabolic process 2.419010e-5
GO:0018924 mandelate metabolic process 2.419010e-5
GO:0007586 digestion 2.469217e-5
GO:0072358 cardiovascular system development 2.528146e-5
GO:0071593 lymphocyte aggregation 2.655240e-5
GO:0090022 regulation of neutrophil chemotaxis 2.656017e-5
GO:0030198 extracellular matrix organization 2.668358e-5
GO:0031647 regulation of protein stability 2.714848e-5
GO:0060343 trabecula formation 2.736436e-5
GO:0002690 positive regulation of leukocyte chemotaxis 2.748598e-5
GO:0001101 response to acid 2.752657e-5
GO:0045787 positive regulation of cell cycle 2.800561e-5
GO:0045670 regulation of osteoclast differentiation 2.815243e-5
GO:0048869 cellular developmental process 2.923143e-5
GO:0045088 regulation of innate immune response 2.932976e-5
GO:0050729 positive regulation of inflammatory response 3.022014e-5
GO:0090031 positive regulation of steroid hormone biosynthetic process 3.028256e-5
GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 3.190475e-5
GO:0051533 positive regulation of NFAT protein import into nucleus 3.310729e-5
GO:0002739 regulation of cytokine secretion involved in immune response 3.325734e-5
GO:0051341 regulation of oxidoreductase activity 3.338508e-5
GO:0032651 regulation of interleukin-1 beta production 3.457813e-5
GO:0032691 negative regulation of interleukin-1 beta production 3.475031e-5
GO:0031399 regulation of protein modification process 3.480337e-5
GO:0006878 cellular copper ion homeostasis 3.482086e-5
GO:0003008 system process 3.556020e-5
GO:0048259 regulation of receptor-mediated endocytosis 3.646536e-5
GO:0051249 regulation of lymphocyte activation 3.727134e-5
GO:0034369 plasma lipoprotein particle remodeling 3.828623e-5
GO:0030155 regulation of cell adhesion 3.928912e-5
GO:0046637 regulation of alpha-beta T cell differentiation 3.939154e-5
GO:0043534 blood vessel endothelial cell migration 3.959325e-5
GO:0072676 lymphocyte migration 4.023474e-5
GO:0031589 cell-substrate adhesion 4.101682e-5
GO:0030261 chromosome condensation 4.157372e-5
GO:0055114 oxidation-reduction process 4.185293e-5
GO:0007243 intracellular protein kinase cascade 4.265454e-5
GO:0010755 regulation of plasminogen activation 4.332809e-5
GO:0050805 negative regulation of synaptic transmission 4.384062e-5
GO:0042534 regulation of tumor necrosis factor biosynthetic process 4.424301e-5
GO:0060620 regulation of cholesterol import 4.426252e-5
GO:0051788 response to misfolded protein 4.430035e-5
GO:0001798 positive regulation of type IIa hypersensitivity 4.430035e-5
GO:0002699 positive regulation of immune effector process 4.476828e-5
GO:0009719 response to endogenous stimulus 4.551853e-5
GO:0019852 L-ascorbic acid metabolic process 4.706168e-5
GO:0060351 cartilage development involved in endochondral bone morphogenesis 4.706437e-5
GO:0050862 positive regulation of T cell receptor signaling pathway 4.725316e-5
GO:0019752 carboxylic acid metabolic process 4.823453e-5
GO:0051004 regulation of lipoprotein lipase activity 4.846630e-5
GO:0045785 positive regulation of cell adhesion 4.998288e-5
GO:0007160 cell-matrix adhesion 5.061646e-5
GO:0031349 positive regulation of defense response 5.170718e-5
GO:0050982 detection of mechanical stimulus 5.207951e-5
GO:0014070 response to organic cyclic compound 5.249207e-5
GO:0050671 positive regulation of lymphocyte proliferation 5.328645e-5
GO:0071529 cementum mineralization 5.420718e-5
GO:0071495 cellular response to endogenous stimulus 5.507649e-5
GO:0042180 cellular ketone metabolic process 5.532956e-5
GO:0051239 regulation of multicellular organismal process 5.748685e-5
GO:0045471 response to ethanol 5.783945e-5
GO:0045672 positive regulation of osteoclast differentiation 5.821192e-5
GO:0006422 aspartyl-tRNA aminoacylation 5.887970e-5
GO:2000147 positive regulation of cell motility 5.950041e-5
GO:0010991 negative regulation of SMAD protein complex assembly 6.016570e-5
GO:0016310 phosphorylation 6.120070e-5
GO:0085029 extracellular matrix assembly 6.129206e-5
GO:0080134 regulation of response to stress 6.318574e-5
GO:0007080 mitotic metaphase plate congression 6.438019e-5
GO:0035556 intracellular signal transduction 6.542509e-5
GO:0071310 cellular response to organic substance 6.662748e-5
GO:0007219 Notch signaling pathway 6.664349e-5
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 7.186529e-5
GO:0032880 regulation of protein localization 7.233004e-5
GO:0002883 regulation of hypersensitivity 7.267719e-5
GO:0032946 positive regulation of mononuclear cell proliferation 7.268775e-5
GO:0009605 response to external stimulus 7.493284e-5
GO:0030157 pancreatic juice secretion 7.534770e-5
GO:0045796 negative regulation of intestinal cholesterol absorption 7.849143e-5
GO:0010949 negative regulation of intestinal phytosterol absorption 7.849143e-5
GO:0032074 negative regulation of nuclease activity 7.849143e-5
GO:0042035 regulation of cytokine biosynthetic process 7.999926e-5
GO:0043405 regulation of MAP kinase activity 8.137684e-5
GO:0035966 response to topologically incorrect protein 8.268434e-5
GO:0043279 response to alkaloid 8.274462e-5
GO:0050710 negative regulation of cytokine secretion 8.342325e-5
GO:0051704 multi-organism process 8.396829e-5
GO:0022607 cellular component assembly 8.548793e-5
GO:0050715 positive regulation of cytokine secretion 8.720415e-5
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 8.775958e-5
GO:0032692 negative regulation of interleukin-1 production 8.835524e-5
GO:0048870 cell motility 8.880172e-5
GO:0032652 regulation of interleukin-1 production 9.017603e-5
GO:0055070 copper ion homeostasis 9.169529e-5
GO:0009611 response to wounding 9.182365e-5
GO:0070665 positive regulation of leukocyte proliferation 9.210078e-5
GO:0006954 inflammatory response 9.231075e-5
GO:0051241 negative regulation of multicellular organismal process 9.624016e-5
GO:0030335 positive regulation of cell migration 9.927868e-5
GO:0042110 T cell activation 1.026601e-4
GO:0071803 positive regulation of podosome assembly 1.033551e-4
GO:0051897 positive regulation of protein kinase B signaling cascade 1.045479e-4
GO:0006955 immune response 1.098305e-4
GO:0006959 humoral immune response 1.098463e-4
GO:0045725 positive regulation of glycogen biosynthetic process 1.104221e-4
GO:0048012 hepatocyte growth factor receptor signaling pathway 1.104221e-4
GO:0050892 intestinal absorption 1.178885e-4
GO:0042993 positive regulation of transcription factor import into nucleus 1.180683e-4
GO:0044085 cellular component biogenesis 1.186627e-4
GO:0050994 regulation of lipid catabolic process 1.192124e-4
GO:0006767 water-soluble vitamin metabolic process 1.199354e-4
GO:0051970 negative regulation of transmission of nerve impulse 1.257912e-4
GO:0044242 cellular lipid catabolic process 1.272566e-4
GO:0046635 positive regulation of alpha-beta T cell activation 1.275713e-4
GO:0050777 negative regulation of immune response 1.276685e-4
GO:0010243 response to organic nitrogen 1.297360e-4
GO:0032071 regulation of endodeoxyribonuclease activity 1.298197e-4
GO:0014059 regulation of dopamine secretion 1.298937e-4
GO:0002376 immune system process 1.301424e-4
GO:0032891 negative regulation of organic acid transport 1.305350e-4
GO:0050711 negative regulation of interleukin-1 secretion 1.312821e-4
GO:0008299 isoprenoid biosynthetic process 1.314597e-4
GO:0019217 regulation of fatty acid metabolic process 1.339115e-4
GO:0045806 negative regulation of endocytosis 1.359584e-4
GO:0030194 positive regulation of blood coagulation 1.364024e-4
GO:0040011 locomotion 1.379988e-4
GO:0060415 muscle tissue morphogenesis 1.404438e-4
GO:0008038 neuron recognition 1.417348e-4
GO:0043434 response to peptide hormone stimulus 1.434904e-4
GO:0045824 negative regulation of innate immune response 1.443348e-4
GO:0060693 regulation of branching involved in salivary gland morphogenesis 1.450849e-4
GO:0006706 steroid catabolic process 1.450849e-4
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1.454280e-4
GO:0051049 regulation of transport 1.471012e-4
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.496540e-4
GO:0006629 lipid metabolic process 1.501745e-4
GO:0007249 I-kappaB kinase/NF-kappaB cascade 1.507489e-4
GO:0043542 endothelial cell migration 1.515121e-4
GO:0032925 regulation of activin receptor signaling pathway 1.527999e-4
GO:0034776 response to histamine 1.533931e-4
GO:0055002 striated muscle cell development 1.571613e-4
GO:0045060 negative thymic T cell selection 1.601355e-4
GO:0060696 regulation of phospholipid catabolic process 1.629024e-4
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 1.629024e-4
GO:0016477 cell migration 1.631951e-4
GO:0090023 positive regulation of neutrophil chemotaxis 1.633990e-4
GO:0043154 negative regulation of caspase activity 1.651636e-4
GO:0034381 plasma lipoprotein particle clearance 1.651748e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.684911e-4
GO:0044058 regulation of digestive system process 1.688004e-4
GO:0040017 positive regulation of locomotion 1.690251e-4
GO:0010900 negative regulation of phosphatidylcholine catabolic process 1.692353e-4
GO:0031650 regulation of heat generation 1.711427e-4
GO:0051346 negative regulation of hydrolase activity 1.724699e-4
GO:0031329 regulation of cellular catabolic process 1.728925e-4
GO:0034375 high-density lipoprotein particle remodeling 1.758194e-4
GO:0042104 positive regulation of activated T cell proliferation 1.769141e-4
GO:0008037 cell recognition 1.799435e-4
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 1.811668e-4
GO:0010718 positive regulation of epithelial to mesenchymal transition 1.853648e-4
GO:0060948 cardiac vascular smooth muscle cell development 1.857794e-4
GO:0048584 positive regulation of response to stimulus 1.862423e-4
GO:0031295 T cell costimulation 1.881637e-4
GO:0032352 positive regulation of hormone metabolic process 1.969807e-4
GO:0006082 organic acid metabolic process 1.982119e-4
GO:0031134 sister chromatid biorientation 1.999839e-4
GO:0001944 vasculature development 2.028848e-4
GO:0055008 cardiac muscle tissue morphogenesis 2.046885e-4
GO:0000165 MAPKKK cascade 2.051207e-4
GO:0015734 taurine transport 2.053401e-4
GO:0006994 positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway 2.053401e-4
GO:0007618 mating 2.058633e-4
GO:0007601 visual perception 2.154733e-4
GO:0031017 exocrine pancreas development 2.162188e-4
GO:0044255 cellular lipid metabolic process 2.167591e-4
GO:0018345 protein palmitoylation 2.168808e-4
GO:0060191 regulation of lipase activity 2.193547e-4
GO:0045089 positive regulation of innate immune response 2.207384e-4
GO:0072376 protein activation cascade 2.249114e-4
GO:0044236 multicellular organismal metabolic process 2.290847e-4
GO:0050850 positive regulation of calcium-mediated signaling 2.327500e-4
GO:0006603 phosphocreatine metabolic process 2.363827e-4
GO:0032655 regulation of interleukin-12 production 2.393527e-4
GO:0051246 regulation of protein metabolic process 2.506890e-4
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 2.509513e-4
GO:0030856 regulation of epithelial cell differentiation 2.515710e-4
GO:0031667 response to nutrient levels 2.544081e-4
GO:0042403 thyroid hormone metabolic process 2.595785e-4
GO:0050820 positive regulation of coagulation 2.619786e-4
GO:0033344 cholesterol efflux 2.624863e-4
GO:0060402 calcium ion transport into cytosol 2.735311e-4
GO:0002718 regulation of cytokine production involved in immune response 2.740806e-4
GO:0034447 very-low-density lipoprotein particle clearance 2.768778e-4
GO:0006429 leucyl-tRNA aminoacylation 2.829363e-4
GO:0030100 regulation of endocytosis 2.852866e-4
GO:0034762 regulation of transmembrane transport 2.856827e-4
GO:0016199 axon midline choice point recognition 2.950386e-4
GO:0042628 mating plug formation 2.959712e-4
GO:0050953 sensory perception of light stimulus 2.990091e-4
GO:0055001 muscle cell development 3.048712e-4
GO:0008610 lipid biosynthetic process 3.083939e-4
GO:0043383 negative T cell selection 3.090870e-4
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 3.108196e-4
GO:2000026 regulation of multicellular organismal development 3.124189e-4
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration 3.126668e-4
GO:0045329 carnitine biosynthetic process 3.126668e-4
GO:0051130 positive regulation of cellular component organization 3.213368e-4
GO:0071247 cellular response to chromate 3.221448e-4
GO:0019060 intracellular transport of viral proteins in host cell 3.221448e-4
GO:0046967 cytosol to ER transport 3.221448e-4
GO:0007156 homophilic cell adhesion 3.249009e-4
GO:0044106 cellular amine metabolic process 3.355507e-4
GO:0042346 positive regulation of NF-kappaB import into nucleus 3.378336e-4
GO:0008207 C21-steroid hormone metabolic process 3.401678e-4
GO:0032026 response to magnesium ion 3.405619e-4
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 3.416984e-4
GO:0018958 phenol-containing compound metabolic process 3.472384e-4
GO:0002526 acute inflammatory response 3.482332e-4
GO:0009100 glycoprotein metabolic process 3.490442e-4
GO:0002697 regulation of immune effector process 3.510295e-4
GO:0006599 phosphagen metabolic process 3.517517e-4
GO:0006957 complement activation, alternative pathway 3.608304e-4
GO:0030595 leukocyte chemotaxis 3.645229e-4
GO:0051051 negative regulation of transport 3.649550e-4
GO:0051043 regulation of membrane protein ectodomain proteolysis 3.704252e-4
GO:0071260 cellular response to mechanical stimulus 3.743373e-4
GO:0051270 regulation of cellular component movement 3.762579e-4
GO:0009725 response to hormone stimulus 3.778688e-4
GO:0051055 negative regulation of lipid biosynthetic process 3.787357e-4
GO:0046628 positive regulation of insulin receptor signaling pathway 3.804229e-4
GO:0010717 regulation of epithelial to mesenchymal transition 3.826017e-4
GO:0034109 homotypic cell-cell adhesion 3.917774e-4
GO:0051048 negative regulation of secretion 3.957412e-4
GO:0071930 negative regulation of transcription involved in G1/S phase of mitotic cell cycle 3.974805e-4
GO:0061097 regulation of protein tyrosine kinase activity 3.984215e-4
GO:0016198 axon choice point recognition 4.010081e-4
GO:0015914 phospholipid transport 4.031792e-4
GO:0030154 cell differentiation 4.038254e-4
GO:0045833 negative regulation of lipid metabolic process 4.043391e-4
GO:0031117 positive regulation of microtubule depolymerization 4.080039e-4
GO:0030334 regulation of cell migration 4.142700e-4
GO:0042058 regulation of epidermal growth factor receptor signaling pathway 4.159742e-4
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 4.204205e-4
GO:2000145 regulation of cell motility 4.420026e-4
GO:0042990 regulation of transcription factor import into nucleus 4.483670e-4
GO:0010759 positive regulation of macrophage chemotaxis 4.504863e-4
GO:0006700 C21-steroid hormone biosynthetic process 4.504863e-4
GO:0042446 hormone biosynthetic process 4.526125e-4
GO:0002819 regulation of adaptive immune response 4.555212e-4
GO:0060457 negative regulation of digestive system process 4.607092e-4
GO:0032070 regulation of deoxyribonuclease activity 4.607092e-4
GO:0019538 protein metabolic process 4.706849e-4
GO:0010565 regulation of cellular ketone metabolic process 4.727077e-4
GO:0006928 cellular component movement 4.792361e-4
GO:0070875 positive regulation of glycogen metabolic process 4.811612e-4
GO:0010757 negative regulation of plasminogen activation 4.923928e-4
GO:0031348 negative regulation of defense response 4.932386e-4
GO:0002763 positive regulation of myeloid leukocyte differentiation 4.961500e-4
GO:0051282 regulation of sequestering of calcium ion 4.975777e-4
GO:0009308 amine metabolic process 5.065909e-4
GO:0032846 positive regulation of homeostatic process 5.263490e-4
GO:0050906 detection of stimulus involved in sensory perception 5.302120e-4
GO:0071385 cellular response to glucocorticoid stimulus 5.335872e-4
GO:0071675 regulation of mononuclear cell migration 5.410420e-4
GO:0071840 cellular component organization or biogenesis 5.418552e-4
GO:0045927 positive regulation of growth 5.608861e-4
GO:0042364 water-soluble vitamin biosynthetic process 5.629343e-4
GO:0048247 lymphocyte chemotaxis 5.677574e-4
GO:0071827 plasma lipoprotein particle organization 5.767402e-4
GO:0060556 regulation of vitamin D biosynthetic process 5.938862e-4
GO:0042304 regulation of fatty acid biosynthetic process 5.978193e-4
GO:0030212 hyaluronan metabolic process 6.021665e-4
GO:0002761 regulation of myeloid leukocyte differentiation 6.069937e-4
GO:0060627 regulation of vesicle-mediated transport 6.132607e-4
GO:0032768 regulation of monooxygenase activity 6.141343e-4
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 6.197498e-4
GO:0060326 cell chemotaxis 6.388549e-4
GO:0001649 osteoblast differentiation 6.421135e-4
GO:0050852 T cell receptor signaling pathway 6.485065e-4
GO:0040012 regulation of locomotion 6.538209e-4
GO:0008356 asymmetric cell division 6.539860e-4