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Novel motif:144

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name:motif144_AAKCMSGT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0052572 response to host immune response 2.843080e-12
GO:0002281 macrophage activation involved in immune response 8.814760e-9
GO:0060764 cell-cell signaling involved in mammary gland development 2.167263e-8
GO:0006741 NADP biosynthetic process 5.375530e-8
GO:0002282 microglial cell activation involved in immune response 5.654206e-8
GO:0052033 pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity 9.434578e-8
GO:0000379 tRNA-type intron splice site recognition and cleavage 1.063385e-7
GO:0060161 positive regulation of dopamine receptor signaling pathway 1.076261e-7
GO:0006863 purine base transport 2.195935e-7
GO:0015855 pyrimidine base transport 2.270535e-7
GO:0048569 post-embryonic organ development 2.979716e-7
GO:0051383 kinetochore organization 3.064916e-7
GO:0015851 nucleobase transport 4.403906e-7
GO:0042632 cholesterol homeostasis 5.025530e-7
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 6.471312e-7
GO:0035409 histone H3-Y41 phosphorylation 7.344917e-7
GO:0008636 activation of caspase activity by protein phosphorylation 7.344917e-7
GO:0051382 kinetochore assembly 7.524164e-7
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 9.797346e-7
GO:0055088 lipid homeostasis 1.010064e-6
GO:0070836 caveola assembly 1.042415e-6
GO:0034111 negative regulation of homotypic cell-cell adhesion 1.498099e-6
GO:0042953 lipoprotein transport 1.640191e-6
GO:0050983 deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase 2.169302e-6
GO:0031081 nuclear pore distribution 2.169302e-6
GO:0015942 formate metabolic process 2.286501e-6
GO:0051646 mitochondrion localization 3.589697e-6
GO:0045019 negative regulation of nitric oxide biosynthetic process 5.432470e-6
GO:0052200 response to host defenses 6.663356e-6
GO:0009396 folic acid-containing compound biosynthetic process 6.826471e-6
GO:0006335 DNA replication-dependent nucleosome assembly 7.672178e-6
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 8.751918e-6
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 8.751918e-6
GO:0016046 detection of fungus 8.751918e-6
GO:0006907 pinocytosis 8.847010e-6
GO:0032971 regulation of muscle filament sliding 8.883585e-6
GO:0051915 induction of synaptic plasticity by chemical substance 9.850825e-6
GO:0060399 positive regulation of growth hormone receptor signaling pathway 1.061019e-5
GO:0015721 bile acid and bile salt transport 1.331285e-5
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion 1.496285e-5
GO:0031959 mineralocorticoid receptor signaling pathway 1.698312e-5
GO:0071529 cementum mineralization 1.754492e-5
GO:0046514 ceramide catabolic process 1.883830e-5
GO:0060334 regulation of interferon-gamma-mediated signaling pathway 2.400394e-5
GO:0015722 canalicular bile acid transport 2.470265e-5
GO:0060574 intestinal epithelial cell maturation 2.572626e-5
GO:0034508 centromere complex assembly 2.652194e-5
GO:0006182 cGMP biosynthetic process 2.888794e-5
GO:0045359 positive regulation of interferon-beta biosynthetic process 2.893504e-5
GO:0051001 negative regulation of nitric-oxide synthase activity 3.139912e-5
GO:0006926 virus-infected cell apoptosis 3.583498e-5
GO:0051354 negative regulation of oxidoreductase activity 3.852014e-5
GO:0030683 evasion by virus of host immune response 3.990828e-5
GO:0007628 adult walking behavior 4.014859e-5
GO:0065004 protein-DNA complex assembly 4.024663e-5
GO:0006853 carnitine shuttle 4.041360e-5
GO:0006529 asparagine biosynthetic process 4.099051e-5
GO:0031116 positive regulation of microtubule polymerization 5.001851e-5
GO:0045357 regulation of interferon-beta biosynthetic process 5.009418e-5
GO:0048676 axon extension involved in development 5.455545e-5
GO:0042993 positive regulation of transcription factor import into nucleus 5.494554e-5
GO:0010799 regulation of peptidyl-threonine phosphorylation 5.528738e-5
GO:0000076 DNA replication checkpoint 5.795651e-5
GO:0034110 regulation of homotypic cell-cell adhesion 6.360660e-5
GO:0031579 membrane raft organization 6.690624e-5
GO:0021509 roof plate formation 6.856339e-5
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 7.165671e-5
GO:0006790 sulfur compound metabolic process 8.145992e-5
GO:0060356 leucine import 8.470982e-5
GO:0006260 DNA replication 8.786570e-5
GO:0042723 thiamine-containing compound metabolic process 8.872516e-5
GO:0046521 sphingoid catabolic process 9.358777e-5
GO:0022408 negative regulation of cell-cell adhesion 1.019432e-4
GO:0070672 response to interleukin-15 1.052648e-4
GO:0060061 Spemann organizer formation 1.102564e-4
GO:0047497 mitochondrion transport along microtubule 1.105659e-4
GO:0015918 sterol transport 1.299368e-4
GO:0031022 nuclear migration along microfilament 1.365918e-4
GO:0015718 monocarboxylic acid transport 1.388294e-4
GO:0048554 positive regulation of metalloenzyme activity 1.394353e-4
GO:0045039 protein import into mitochondrial inner membrane 1.394353e-4
GO:0006598 polyamine catabolic process 1.400465e-4
GO:0032439 endosome localization 1.401380e-4
GO:0032707 negative regulation of interleukin-23 production 1.418481e-4
GO:0060480 lung goblet cell differentiation 1.418481e-4
GO:0030208 dermatan sulfate biosynthetic process 1.418481e-4
GO:0042136 neurotransmitter biosynthetic process 1.431101e-4
GO:0002275 myeloid cell activation involved in immune response 1.440517e-4
GO:0014012 peripheral nervous system axon regeneration 1.472556e-4
GO:0060435 bronchiole development 1.724026e-4
GO:0072530 purine-containing compound transmembrane transport 1.728063e-4
GO:0006641 triglyceride metabolic process 1.781833e-4
GO:0031247 actin rod assembly 1.805358e-4
GO:0002537 nitric oxide production involved in inflammatory response 1.805358e-4
GO:0044258 intestinal lipid catabolic process 1.807135e-4
GO:0018350 protein esterification 1.807135e-4
GO:0060159 regulation of dopamine receptor signaling pathway 1.845243e-4
GO:0070541 response to platinum ion 1.976511e-4
GO:0046653 tetrahydrofolate metabolic process 2.001486e-4
GO:0032222 regulation of synaptic transmission, cholinergic 2.084153e-4
GO:0035722 interleukin-12-mediated signaling pathway 2.117162e-4
GO:0015931 nucleobase-containing compound transport 2.170458e-4
GO:0051642 centrosome localization 2.205875e-4
GO:0071105 response to interleukin-11 2.243257e-4
GO:0006541 glutamine metabolic process 2.322474e-4
GO:0006334 nucleosome assembly 2.337121e-4
GO:0060056 mammary gland involution 2.399233e-4
GO:0009566 fertilization 2.400355e-4
GO:0071320 cellular response to cAMP 2.428381e-4
GO:0002069 columnar/cuboidal epithelial cell maturation 2.559167e-4
GO:0045348 positive regulation of MHC class II biosynthetic process 2.588206e-4
GO:0010722 regulation of ferrochelatase activity 2.788148e-4
GO:0051292 nuclear pore complex assembly 2.956513e-4
GO:0016338 calcium-independent cell-cell adhesion 2.997304e-4
GO:0051450 myoblast proliferation 3.077528e-4
GO:0032365 intracellular lipid transport 3.080281e-4
GO:0032929 negative regulation of superoxide anion generation 3.088167e-4
GO:0034723 DNA replication-dependent nucleosome organization 3.088167e-4
GO:0006898 receptor-mediated endocytosis 3.113644e-4
GO:0001774 microglial cell activation 3.140420e-4
GO:0001300 chronological cell aging 3.163037e-4
GO:0007262 STAT protein import into nucleus 3.249170e-4
GO:0015793 glycerol transport 3.249170e-4
GO:0006639 acylglycerol metabolic process 3.345176e-4
GO:0009064 glutamine family amino acid metabolic process 3.623323e-4
GO:0030901 midbrain development 3.877694e-4
GO:0030301 cholesterol transport 3.907769e-4
GO:0061143 alveolar primary septum development 4.038126e-4
GO:0071824 protein-DNA complex subunit organization 4.125951e-4
GO:0001839 neural plate morphogenesis 4.149613e-4
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion 4.265288e-4
GO:0034373 intermediate-density lipoprotein particle remodeling 4.412424e-4
GO:0060398 regulation of growth hormone receptor signaling pathway 4.418354e-4
GO:0032609 interferon-gamma production 4.703927e-4
GO:0032769 negative regulation of monooxygenase activity 4.787824e-4
GO:0006290 pyrimidine dimer repair 4.840991e-4
GO:0045653 negative regulation of megakaryocyte differentiation 4.895260e-4
GO:0051659 maintenance of mitochondrion location 4.912845e-4
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 4.912845e-4
GO:0051310 metaphase plate congression 4.925270e-4
GO:0031077 post-embryonic camera-type eye development 5.059629e-4
GO:0045638 negative regulation of myeloid cell differentiation 5.172739e-4
GO:0006540 glutamate decarboxylation to succinate 5.254467e-4
GO:0035456 response to interferon-beta 5.317246e-4
GO:0031112 positive regulation of microtubule polymerization or depolymerization 5.909108e-4
GO:0034374 low-density lipoprotein particle remodeling 5.960012e-4
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 6.035557e-4
GO:0015849 organic acid transport 6.143337e-4
GO:0034346 positive regulation of type III interferon production 6.502809e-4
GO:0006406 mRNA export from nucleus 7.095045e-4
GO:0033561 regulation of water loss via skin 7.187543e-4
GO:0000105 histidine biosynthetic process 7.187543e-4
GO:0046677 response to antibiotic 7.199062e-4
GO:0035564 regulation of kidney size 7.634373e-4
GO:0031915 positive regulation of synaptic plasticity 7.649268e-4
GO:0042755 eating behavior 7.900524e-4
GO:0031103 axon regeneration 8.160116e-4
GO:0006760 folic acid-containing compound metabolic process 8.199165e-4
GO:0044062 regulation of excretion 8.361554e-4
GO:0006638 neutral lipid metabolic process 8.503856e-4
GO:0019836 hemolysis by symbiont of host erythrocytes 8.510800e-4
GO:0006405 RNA export from nucleus 8.551884e-4
GO:0015827 tryptophan transport 8.608980e-4
GO:0015837 amine transport 8.634003e-4
GO:0051654 establishment of mitochondrion localization 8.925016e-4
GO:0033683 nucleotide-excision repair, DNA incision 9.042896e-4
GO:0016137 glycoside metabolic process 9.042896e-4
GO:0060395 SMAD protein signal transduction 9.813865e-4
GO:0090193 positive regulation of glomerulus development 9.854970e-4
GO:0032055 negative regulation of translation in response to stress 9.854970e-4
GO:0006620 posttranslational protein targeting to membrane 9.854970e-4
GO:0006108 malate metabolic process 9.956751e-4
GO:0042157 lipoprotein metabolic process 1.013872e-3
GO:0071318 cellular response to ATP 1.052751e-3
GO:0043508 negative regulation of JUN kinase activity 1.053437e-3
GO:0060638 mesenchymal-epithelial cell signaling 1.072599e-3
GO:2000173 negative regulation of branching morphogenesis of a nerve 1.080790e-3
GO:0019079 viral genome replication 1.080961e-3
GO:0006668 sphinganine-1-phosphate metabolic process 1.084834e-3
GO:0034638 phosphatidylcholine catabolic process 1.114776e-3
GO:0016125 sterol metabolic process 1.121458e-3
GO:0044003 modification by symbiont of host morphology or physiology 1.151913e-3
GO:0003333 amino acid transmembrane transport 1.166556e-3
GO:0002237 response to molecule of bacterial origin 1.180200e-3
GO:0030204 chondroitin sulfate metabolic process 1.186824e-3
GO:0009617 response to bacterium 1.196413e-3
GO:0035458 cellular response to interferon-beta 1.216691e-3
GO:0034372 very-low-density lipoprotein particle remodeling 1.221913e-3
GO:0006413 translational initiation 1.246497e-3
GO:0061038 uterus morphogenesis 1.317628e-3
GO:0006528 asparagine metabolic process 1.322341e-3
GO:0016139 glycoside catabolic process 1.322721e-3
GO:0015872 dopamine transport 1.373817e-3
GO:0046942 carboxylic acid transport 1.375015e-3
GO:0006869 lipid transport 1.405371e-3
GO:0009744 response to sucrose stimulus 1.437797e-3
GO:0035356 cellular triglyceride homeostasis 1.475150e-3
GO:0007162 negative regulation of cell adhesion 1.540146e-3
GO:0033629 negative regulation of cell adhesion mediated by integrin 1.570564e-3
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 1.571345e-3
GO:0032760 positive regulation of tumor necrosis factor production 1.628480e-3
GO:0060644 mammary gland epithelial cell differentiation 1.687176e-3
GO:0045210 FasL biosynthetic process 1.745749e-3
GO:0042753 positive regulation of circadian rhythm 1.748625e-3
GO:0030104 water homeostasis 1.776326e-3
GO:0052509 positive regulation by symbiont of host defense response 1.787608e-3
GO:0015820 leucine transport 1.849287e-3
GO:0001840 neural plate development 1.851448e-3
GO:0021700 developmental maturation 1.854365e-3
GO:0030853 negative regulation of granulocyte differentiation 1.864135e-3
GO:0070328 triglyceride homeostasis 2.001139e-3
GO:0060401 cytosolic calcium ion transport 2.010514e-3
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 2.058092e-3
GO:0046689 response to mercury ion 2.069939e-3
GO:0042116 macrophage activation 2.069939e-3
GO:0009066 aspartate family amino acid metabolic process 2.150598e-3
GO:0060712 spongiotrophoblast layer development 2.154062e-3
GO:0042158 lipoprotein biosynthetic process 2.176074e-3
GO:0060306 regulation of membrane repolarization 2.243393e-3
GO:0071379 cellular response to prostaglandin stimulus 2.287539e-3
GO:2000096 positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway 2.295224e-3
GO:0035813 regulation of renal sodium excretion 2.325783e-3
GO:0006772 thiamine metabolic process 2.332217e-3
GO:0002064 epithelial cell development 2.332300e-3
GO:0048388 endosomal lumen acidification 2.344204e-3
GO:0071673 positive regulation of smooth muscle cell chemotaxis 2.344204e-3
GO:0007210 serotonin receptor signaling pathway 2.392896e-3
GO:0019896 axon transport of mitochondrion 2.442685e-3
GO:0016925 protein sumoylation 2.450554e-3
GO:0010889 regulation of sequestering of triglyceride 2.461243e-3
GO:0042159 lipoprotein catabolic process 2.472546e-3
GO:0060118 vestibular receptor cell development 2.571272e-3
GO:0030704 vitelline membrane formation 2.571272e-3
GO:0014827 intestine smooth muscle contraction 2.644247e-3
GO:0010106 cellular response to iron ion starvation 2.698238e-3
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 2.721922e-3
GO:0031989 bombesin receptor signaling pathway 2.745513e-3
GO:0045346 regulation of MHC class II biosynthetic process 2.866868e-3
GO:0035166 post-embryonic hemopoiesis 2.894848e-3
GO:0061028 establishment of endothelial barrier 3.026613e-3
GO:0043555 regulation of translation in response to stress 3.078293e-3
GO:0022007 convergent extension involved in neural plate elongation 3.097845e-3
GO:0071702 organic substance transport 3.106665e-3
GO:0050884 neuromuscular process controlling posture 3.128681e-3
GO:2000344 positive regulation of acrosome reaction 3.158930e-3
GO:0034379 very-low-density lipoprotein particle assembly 3.159852e-3
GO:0007252 I-kappaB phosphorylation 3.176378e-3
GO:0018065 protein-cofactor linkage 3.193469e-3
GO:0050654 chondroitin sulfate proteoglycan metabolic process 3.249512e-3
GO:0002070 epithelial cell maturation 3.282352e-3
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.311272e-3
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 3.328894e-3
GO:0045773 positive regulation of axon extension 3.372858e-3
GO:0042559 pteridine-containing compound biosynthetic process 3.390854e-3
GO:0072531 pyrimidine-containing compound transmembrane transport 3.418955e-3
GO:0001514 selenocysteine incorporation 3.432502e-3
GO:0031952 regulation of protein autophosphorylation 3.442252e-3
GO:0007631 feeding behavior 3.450336e-3
GO:0006029 proteoglycan metabolic process 3.495972e-3
GO:0071705 nitrogen compound transport 3.535729e-3
GO:0007062 sister chromatid cohesion 3.545883e-3
GO:0035803 egg coat formation 3.562068e-3
GO:0070302 regulation of stress-activated protein kinase signaling cascade 3.603580e-3
GO:0031642 negative regulation of myelination 3.608527e-3
GO:0031953 negative regulation of protein autophosphorylation 3.621107e-3
GO:0021527 spinal cord association neuron differentiation 3.693122e-3
GO:0019433 triglyceride catabolic process 3.697926e-3
GO:0006662 glycerol ether metabolic process 3.737929e-3
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway 3.761066e-3
GO:0060464 lung lobe formation 3.817078e-3
GO:0046588 negative regulation of calcium-dependent cell-cell adhesion 3.817078e-3
GO:0032981 mitochondrial respiratory chain complex I assembly 3.852067e-3
GO:0009187 cyclic nucleotide metabolic process 3.878864e-3
GO:0045713 low-density lipoprotein particle receptor biosynthetic process 3.959401e-3
GO:0033590 response to cobalamin 3.959401e-3
GO:0003290 atrial septum secundum morphogenesis 3.959401e-3
GO:0006117 acetaldehyde metabolic process 3.959401e-3
GO:0072321 chaperone-mediated protein transport 3.989467e-3
GO:0045687 positive regulation of glial cell differentiation 4.016836e-3
GO:0048312 intracellular distribution of mitochondria 4.130653e-3
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 4.130653e-3
GO:0051647 nucleus localization 4.132086e-3
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway 4.186939e-3
GO:0045212 neurotransmitter receptor biosynthetic process 4.186939e-3
GO:0032223 negative regulation of synaptic transmission, cholinergic 4.186939e-3
GO:0045947 negative regulation of translational initiation 4.336396e-3
GO:0031497 chromatin assembly 4.343540e-3
GO:0000186 activation of MAPKK activity 4.419831e-3
GO:0016226 iron-sulfur cluster assembly 4.530866e-3
GO:0048012 hepatocyte growth factor receptor signaling pathway 4.532754e-3
GO:0032497 detection of lipopolysaccharide 4.581120e-3
GO:0060539 diaphragm development 4.618995e-3
GO:0040023 establishment of nucleus localization 4.640992e-3
GO:0007204 elevation of cytosolic calcium ion concentration 4.697110e-3
GO:0045446 endothelial cell differentiation 4.699572e-3
GO:0060575 intestinal epithelial cell differentiation 4.725964e-3
GO:0060339 negative regulation of type I interferon-mediated signaling pathway 4.730725e-3
GO:0008216 spermidine metabolic process 4.730725e-3
GO:0015879 carnitine transport 4.753202e-3
GO:0045472 response to ether 4.783217e-3
GO:0019230 proprioception 4.818946e-3
GO:0046475 glycerophospholipid catabolic process 4.836472e-3
GO:0006467 protein thiol-disulfide exchange 4.867919e-3
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 4.874287e-3
GO:0031223 auditory behavior 4.948792e-3
GO:0010884 positive regulation of lipid storage 5.168676e-3
GO:0006813 potassium ion transport 5.199893e-3
GO:0030157 pancreatic juice secretion 5.204986e-3
GO:0042346 positive regulation of NF-kappaB import into nucleus 5.274322e-3
GO:0030855 epithelial cell differentiation 5.307807e-3
GO:0032647 regulation of interferon-alpha production 5.334308e-3
GO:0035815 positive regulation of renal sodium excretion 5.334308e-3
GO:0060968 regulation of gene silencing 5.339596e-3
GO:0031114 regulation of microtubule depolymerization 5.381358e-3
GO:0009595 detection of biotic stimulus 5.423308e-3
GO:0044242 cellular lipid catabolic process 5.490291e-3
GO:0090331 negative regulation of platelet aggregation 5.527760e-3
GO:0061110 dense core granule biogenesis 5.527760e-3
GO:0042628 mating plug formation 5.527760e-3
GO:0061108 seminal vesicle epithelium development 5.527760e-3
GO:0010248 establishment or maintenance of transmembrane electrochemical gradient 5.530298e-3
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 5.620791e-3
GO:0061162 establishment of monopolar cell polarity 5.626055e-3
GO:0070207 protein homotrimerization 5.752551e-3
GO:0051099 positive regulation of binding 5.753057e-3
GO:0045540 regulation of cholesterol biosynthetic process 5.757532e-3
GO:0052565 response to defense-related host nitric oxide production 5.789420e-3
GO:0030844 positive regulation of intermediate filament depolymerization 5.789420e-3
GO:0007097 nuclear migration 5.832314e-3
GO:0009649 entrainment of circadian clock 5.875719e-3
GO:0031558 induction of apoptosis in response to chemical stimulus 5.930866e-3
GO:0045345 positive regulation of MHC class I biosynthetic process 5.959094e-3
GO:0010876 lipid localization 6.153379e-3
GO:0015791 polyol transport 6.173054e-3
GO:0007026 negative regulation of microtubule depolymerization 6.220145e-3
GO:0071104 response to interleukin-9 6.256698e-3
GO:0060691 epithelial cell maturation involved in salivary gland development 6.256698e-3
GO:0033292 T-tubule organization 6.256698e-3
GO:0060096 serotonin secretion, neurotransmission 6.256698e-3
GO:0060299 negative regulation of sarcomere organization 6.256698e-3
GO:0061205 paramesonephric duct development 6.311773e-3
GO:0032928 regulation of superoxide anion generation 6.383088e-3
GO:0048711 positive regulation of astrocyte differentiation 6.457816e-3
GO:0072134 nephrogenic mesenchyme morphogenesis 6.466884e-3
GO:0003184 pulmonary valve morphogenesis 6.466884e-3
GO:0032057 negative regulation of translational initiation in response to stress 6.466884e-3
GO:0044089 positive regulation of cellular component biogenesis 6.574529e-3
GO:0031557 induction of programmed cell death in response to chemical stimulus 6.626170e-3
GO:0060662 salivary gland cavitation 6.784513e-3
GO:0032006 regulation of TOR signaling cascade 6.830348e-3
GO:0034728 nucleosome organization 6.840558e-3
GO:0007007 inner mitochondrial membrane organization 6.871834e-3
GO:0060402 calcium ion transport into cytosol 6.942524e-3
GO:0001885 endothelial cell development 7.039359e-3
GO:0010389 regulation of G2/M transition of mitotic cell cycle 7.101814e-3
GO:0006706 steroid catabolic process 7.127888e-3
GO:0018283 iron incorporation into metallo-sulfur cluster 7.175615e-3
GO:0010890 positive regulation of sequestering of triglyceride 7.243254e-3
GO:0031427 response to methotrexate 7.513403e-3
GO:0032799 low-density lipoprotein receptor particle metabolic process 7.513403e-3
GO:0018352 protein-pyridoxal-5-phosphate linkage 7.513403e-3
GO:0000718 nucleotide-excision repair, DNA damage removal 7.562143e-3
GO:0045792 negative regulation of cell size 7.731573e-3
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 7.780023e-3
GO:0030490 maturation of SSU-rRNA 7.826597e-3
GO:0046477 glycosylceramide catabolic process 7.826597e-3
GO:0051028 mRNA transport 7.851415e-3
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 7.890461e-3
GO:0042255 ribosome assembly 7.933574e-3
GO:0046039 GTP metabolic process 7.950828e-3
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 8.002903e-3
GO:0046464 acylglycerol catabolic process 8.375903e-3
GO:0071671 regulation of smooth muscle cell chemotaxis 8.434440e-3
GO:0019255 glucose 1-phosphate metabolic process 8.434440e-3
GO:0060482 lobar bronchus development 8.434440e-3
GO:0034370 triglyceride-rich lipoprotein particle remodeling 8.572736e-3
GO:0071827 plasma lipoprotein particle organization 8.675482e-3
GO:0014015 positive regulation of gliogenesis 8.806646e-3
GO:0010572 positive regulation of platelet activation 8.876000e-3
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 8.896771e-3
GO:0061002 negative regulation of dendritic spine morphogenesis 8.973667e-3
GO:0060466 activation of meiosis involved in egg activation 8.973667e-3
GO:0000920 cytokinetic cell separation 8.973667e-3
GO:0008206 bile acid metabolic process 9.027403e-3
GO:0032781 positive regulation of ATPase activity 9.050261e-3
GO:0042420 dopamine catabolic process 9.070691e-3
GO:0006542 glutamine biosynthetic process 9.184933e-3
GO:0006612 protein targeting to membrane 9.226951e-3
GO:0042977 activation of JAK2 kinase activity 9.262890e-3
GO:0042305 specification of segmental identity, mandibular segment 9.290409e-3
GO:0002033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure 9.290409e-3
GO:0018184 protein polyamination 9.290409e-3
GO:0048678 response to axon injury 9.296975e-3
GO:0006739 NADP metabolic process 9.370479e-3
GO:0045630 positive regulation of T-helper 2 cell differentiation 9.521346e-3
GO:0060711 labyrinthine layer development 9.537681e-3
GO:0018209 peptidyl-serine modification 9.555511e-3
GO:2000052 positive regulation of non-canonical Wnt receptor signaling pathway 9.592155e-3
GO:0043585 nose morphogenesis 9.592155e-3
GO:0030308 negative regulation of cell growth 9.593676e-3
GO:0030317 sperm motility 9.604014e-3
GO:0070671 response to interleukin-12 9.741456e-3
GO:0002066 columnar/cuboidal epithelial cell development 9.821674e-3
GO:0042274 ribosomal small subunit biogenesis 9.933439e-3
GO:0006848 pyruvate transport 9.946947e-3
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 9.946947e-3
GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 9.946947e-3
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 9.946947e-3
GO:0031648 protein destabilization 1.005558e-2
GO:0051320 S phase 1.008017e-2
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 1.015134e-2
GO:0015810 aspartate transport 1.026278e-2
GO:0061156 pulmonary artery morphogenesis 1.029235e-2
GO:0071360 cellular response to exogenous dsRNA 1.035196e-2
GO:0050999 regulation of nitric-oxide synthase activity 1.041693e-2
GO:0060708 spongiotrophoblast differentiation 1.045447e-2
GO:0006403 RNA localization 1.067208e-2
GO:0006184 GTP catabolic process 1.078802e-2
GO:0050651 dermatan sulfate proteoglycan biosynthetic process 1.083826e-2
GO:0046330 positive regulation of JNK cascade 1.089715e-2
GO:0014056 regulation of acetylcholine secretion 1.099496e-2
GO:0070483 detection of hypoxia 1.099496e-2
GO:0045343 regulation of MHC class I biosynthetic process 1.104322e-2
GO:0007064 mitotic sister chromatid cohesion 1.106484e-2
GO:0008078 mesodermal cell migration 1.110234e-2
GO:0048844 artery morphogenesis 1.118617e-2
GO:0030149 sphingolipid catabolic process 1.126541e-2
GO:0010761 fibroblast migration 1.126541e-2
GO:0060765 regulation of androgen receptor signaling pathway 1.127125e-2
GO:0034764 positive regulation of transmembrane transport 1.140855e-2
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 1.166946e-2
GO:0046328 regulation of JNK cascade 1.175966e-2
GO:0051100 negative regulation of binding 1.196785e-2
GO:0060338 regulation of type I interferon-mediated signaling pathway 1.197401e-2
GO:0007638 mechanosensory behavior 1.200083e-2
GO:0048563 post-embryonic organ morphogenesis 1.200914e-2
GO:0015801 aromatic amino acid transport 1.200914e-2
GO:0046113 nucleobase catabolic process 1.205947e-2
GO:0001937 negative regulation of endothelial cell proliferation 1.215221e-2
GO:0060046 regulation of acrosome reaction 1.217757e-2
GO:0033108 mitochondrial respiratory chain complex assembly 1.226225e-2
GO:0003158 endothelium development 1.227318e-2
GO:0032008 positive regulation of TOR signaling cascade 1.233334e-2
GO:0006983 ER overload response 1.244433e-2
GO:0007597 blood coagulation, intrinsic pathway 1.257403e-2
GO:0051668 localization within membrane 1.259798e-2
GO:0007218 neuropeptide signaling pathway 1.259934e-2
GO:0050658 RNA transport 1.262827e-2
GO:0032757 positive regulation of interleukin-8 production 1.265037e-2
GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway 1.270780e-2
GO:0045356 positive regulation of interferon-alpha biosynthetic process 1.270780e-2
GO:0051701 interaction with host 1.279772e-2
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 1.285351e-2
GO:0014040 positive regulation of Schwann cell differentiation 1.285351e-2
GO:0006177 GMP biosynthetic process 1.285351e-2
GO:0051657 maintenance of organelle location 1.292270e-2
GO:0006835 dicarboxylic acid transport 1.299989e-2
GO:0034369 plasma lipoprotein particle remodeling 1.311892e-2
GO:0030206 chondroitin sulfate biosynthetic process 1.313488e-2
GO:0060535 trachea cartilage morphogenesis 1.320226e-2
GO:0048639 positive regulation of developmental growth 1.324289e-2
GO:0032092 positive regulation of protein binding 1.345552e-2
GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade 1.372154e-2
GO:0010713 negative regulation of collagen metabolic process 1.372154e-2
GO:0046549 retinal cone cell development 1.372872e-2
GO:0050655 dermatan sulfate proteoglycan metabolic process 1.372872e-2
GO:0006555 methionine metabolic process 1.378235e-2
GO:0022614 membrane to membrane docking 1.383734e-2
GO:2000095 regulation of Wnt receptor signaling pathway, planar cell polarity pathway 1.386080e-2
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 1.401124e-2
GO:0046503 glycerolipid catabolic process 1.429090e-2
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 1.429247e-2
GO:0014057 positive regulation of acetylcholine secretion 1.429247e-2
GO:0006412 translation 1.431914e-2
GO:0071243 cellular response to arsenic-containing substance 1.435625e-2
GO:0051712 positive regulation of killing of cells of other organism 1.435625e-2
GO:0060998 regulation of dendritic spine development 1.437014e-2
GO:0051205 protein insertion into membrane 1.444005e-2
GO:0007416 synapse assembly 1.481847e-2
GO:0031123 RNA 3'-end processing 1.484166e-2
GO:0090322 regulation of superoxide metabolic process 1.504304e-2
GO:0046795 intracellular virion transport 1.505485e-2
GO:0046341 CDP-diacylglycerol metabolic process 1.505485e-2
GO:0006164 purine nucleotide biosynthetic process 1.507271e-2
GO:0032633 interleukin-4 production 1.509016e-2
GO:0001865 NK T cell differentiation 1.509016e-2
GO:0043314 negative regulation of neutrophil degranulation 1.558293e-2
GO:0042508 tyrosine phosphorylation of Stat1 protein 1.558293e-2
GO:0051098 regulation of binding 1.564512e-2
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 1.568106e-2
GO:0032496 response to lipopolysaccharide 1.573920e-2
GO:0030203 glycosaminoglycan metabolic process 1.574003e-2
GO:0002030 inhibitory G-protein coupled receptor phosphorylation 1.579253e-2
GO:0033326 cerebrospinal fluid secretion 1.584274e-2
GO:0008203 cholesterol metabolic process 1.591733e-2
GO:0006865 amino acid transport 1.591733e-2
GO:0051480 cytosolic calcium ion homeostasis 1.592736e-2
GO:0042558 pteridine-containing compound metabolic process 1.601497e-2
GO:0070212 protein poly-ADP-ribosylation 1.601630e-2
GO:0043393 regulation of protein binding 1.615502e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0048240 sperm capacitation 1.603861e-13
GO:0060074 synapse maturation 6.365769e-9
GO:0010722 regulation of ferrochelatase activity 1.359664e-8
GO:0043461 proton-transporting ATP synthase complex assembly 1.953500e-8
GO:0010872 regulation of cholesterol esterification 3.442389e-8
GO:0010873 positive regulation of cholesterol esterification 4.246618e-8
GO:0060971 embryonic heart tube left/right pattern formation 1.528670e-7
GO:0007258 JUN phosphorylation 1.905140e-7
GO:0045210 FasL biosynthetic process 3.120332e-7
GO:0032765 positive regulation of mast cell cytokine production 3.120332e-7
GO:0002431 Fc receptor mediated stimulatory signaling pathway 3.120332e-7
GO:0007254 JNK cascade 4.329923e-7
GO:0032915 positive regulation of transforming growth factor beta2 production 5.944495e-7
GO:0031098 stress-activated protein kinase signaling cascade 7.252970e-7
GO:0070286 axonemal dynein complex assembly 1.523891e-6
GO:0060764 cell-cell signaling involved in mammary gland development 1.638170e-6
GO:0016540 protein autoprocessing 2.082320e-6
GO:0018283 iron incorporation into metallo-sulfur cluster 2.282429e-6
GO:0001805 positive regulation of type III hypersensitivity 4.231432e-6
GO:0019230 proprioception 4.945292e-6
GO:0045963 negative regulation of dopamine metabolic process 5.583484e-6
GO:0050668 positive regulation of homocysteine metabolic process 5.583484e-6
GO:0007586 digestion 5.906968e-6
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 7.006798e-6
GO:0009169 purine ribonucleoside monophosphate catabolic process 7.376614e-6
GO:0007286 spermatid development 8.388427e-6
GO:2000781 positive regulation of double-strand break repair 8.493952e-6
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 8.677865e-6
GO:0071071 regulation of phospholipid biosynthetic process 9.698921e-6
GO:0043129 surfactant homeostasis 1.213236e-5
GO:0071214 cellular response to abiotic stimulus 1.272974e-5
GO:0000302 response to reactive oxygen species 1.363495e-5
GO:0070071 proton-transporting two-sector ATPase complex assembly 1.735718e-5
GO:0060928 atrioventricular node cell development 2.164164e-5
GO:0060929 atrioventricular node cell fate commitment 2.164164e-5
GO:0003168 cardiac Purkinje fiber cell differentiation 2.164164e-5
GO:0015739 sialic acid transport 2.164164e-5
GO:0006258 UDP-glucose catabolic process 2.164164e-5
GO:0003342 proepicardium development 2.164164e-5
GO:0006011 UDP-glucose metabolic process 2.393402e-5
GO:0043691 reverse cholesterol transport 2.591787e-5
GO:0070482 response to oxygen levels 2.673928e-5
GO:0071072 negative regulation of phospholipid biosynthetic process 2.827663e-5
GO:0001812 positive regulation of type I hypersensitivity 3.231756e-5
GO:0006783 heme biosynthetic process 3.515303e-5
GO:0030149 sphingolipid catabolic process 3.668889e-5
GO:0006611 protein export from nucleus 4.015040e-5
GO:0034599 cellular response to oxidative stress 4.062683e-5
GO:0007501 mesodermal cell fate specification 4.205907e-5
GO:0046466 membrane lipid catabolic process 4.216725e-5
GO:0046148 pigment biosynthetic process 4.701682e-5
GO:0048554 positive regulation of metalloenzyme activity 4.718466e-5
GO:0018364 peptidyl-glutamine methylation 4.902864e-5
GO:0051176 positive regulation of sulfur metabolic process 6.023856e-5
GO:0001666 response to hypoxia 6.234103e-5
GO:0000305 response to oxygen radical 6.860862e-5
GO:0042053 regulation of dopamine metabolic process 7.358922e-5
GO:0060620 regulation of cholesterol import 8.170741e-5
GO:0003029 detection of hypoxic conditions in blood by carotid body chemoreceptor signaling 8.892186e-5
GO:0014074 response to purine-containing compound 9.168994e-5
GO:0030300 regulation of intestinal cholesterol absorption 1.036832e-4
GO:0032049 cardiolipin biosynthetic process 1.057714e-4
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.057714e-4
GO:0042742 defense response to bacterium 1.162416e-4
GO:0065005 protein-lipid complex assembly 1.174593e-4
GO:0060695 negative regulation of cholesterol transporter activity 1.191090e-4
GO:0060480 lung goblet cell differentiation 1.191090e-4
GO:0015759 beta-glucoside transport 1.191090e-4
GO:0055072 iron ion homeostasis 1.244543e-4
GO:0051865 protein autoubiquitination 1.273042e-4
GO:0031000 response to caffeine 1.318931e-4
GO:0008356 asymmetric cell division 1.436824e-4
GO:0060574 intestinal epithelial cell maturation 1.557919e-4
GO:0042069 regulation of catecholamine metabolic process 1.662293e-4
GO:0048515 spermatid differentiation 1.677680e-4
GO:0002385 mucosal immune response 1.734767e-4
GO:0072592 oxygen metabolic process 1.757105e-4
GO:0038007 netrin-activated signaling pathway 1.765836e-4
GO:0006621 protein retention in ER lumen 1.834659e-4
GO:0001798 positive regulation of type IIa hypersensitivity 1.888330e-4
GO:0006003 fructose 2,6-bisphosphate metabolic process 1.904481e-4
GO:0070318 positive regulation of G0 to G1 transition 1.957785e-4
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 1.957785e-4
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 1.957785e-4
GO:0032230 positive regulation of synaptic transmission, GABAergic 2.038010e-4
GO:0021604 cranial nerve structural organization 2.179731e-4
GO:0006188 IMP biosynthetic process 2.244078e-4
GO:0001810 regulation of type I hypersensitivity 2.244078e-4
GO:0034508 centromere complex assembly 2.335716e-4
GO:0051341 regulation of oxidoreductase activity 2.343112e-4
GO:0071034 CUT catabolic process 2.515987e-4
GO:0043312 neutrophil degranulation 2.515987e-4
GO:0051382 kinetochore assembly 2.515987e-4
GO:0002251 organ or tissue specific immune response 2.616650e-4
GO:0071843 cellular component biogenesis at cellular level 2.820564e-4
GO:0032048 cardiolipin metabolic process 2.823428e-4
GO:0046835 carbohydrate phosphorylation 2.830627e-4
GO:0033005 positive regulation of mast cell activation 2.868770e-4
GO:0046129 purine ribonucleoside biosynthetic process 2.890064e-4
GO:0051168 nuclear export 3.226550e-4
GO:0007281 germ cell development 3.444083e-4
GO:0046033 AMP metabolic process 3.459219e-4
GO:0072384 organelle transport along microtubule 3.497590e-4
GO:0042946 glucoside transport 3.510436e-4
GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly 3.510436e-4
GO:0060576 intestinal epithelial cell development 3.899888e-4
GO:0071478 cellular response to radiation 3.947038e-4
GO:0010845 positive regulation of reciprocal meiotic recombination 3.964203e-4
GO:0006855 drug transmembrane transport 3.975819e-4
GO:0050798 activated T cell proliferation 4.144745e-4
GO:0033026 negative regulation of mast cell apoptosis 4.348759e-4
GO:0042135 neurotransmitter catabolic process 4.418174e-4
GO:0006707 cholesterol catabolic process 4.418174e-4
GO:0042168 heme metabolic process 4.623522e-4
GO:0034435 cholesterol esterification 4.652476e-4
GO:0072661 protein targeting to plasma membrane 4.787718e-4
GO:0042398 cellular modified amino acid biosynthetic process 5.000383e-4
GO:0033554 cellular response to stress 5.127094e-4
GO:0016558 protein import into peroxisome matrix 5.315066e-4
GO:0070316 regulation of G0 to G1 transition 5.544116e-4
GO:0045416 positive regulation of interleukin-8 biosynthetic process 5.562950e-4
GO:0090045 positive regulation of deacetylase activity 5.894156e-4
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 5.894156e-4
GO:0008615 pyridoxine biosynthetic process 5.894156e-4
GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback 5.920587e-4
GO:0002542 Factor XII activation 5.920587e-4
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 6.200298e-4
GO:0009167 purine ribonucleoside monophosphate metabolic process 6.322205e-4
GO:0051262 protein tetramerization 6.363190e-4
GO:0030970 retrograde protein transport, ER to cytosol 6.399492e-4
GO:0042420 dopamine catabolic process 6.482735e-4
GO:0022600 digestive system process 6.588354e-4
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 6.589647e-4
GO:0043620 regulation of DNA-dependent transcription in response to stress 6.888142e-4
GO:0006979 response to oxidative stress 7.851723e-4
GO:0042440 pigment metabolic process 7.921373e-4
GO:0048532 anatomical structure arrangement 7.994814e-4
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 8.033953e-4
GO:0046086 adenosine biosynthetic process 8.374057e-4
GO:0010045 response to nickel ion 8.374057e-4
GO:0006196 AMP catabolic process 8.374057e-4
GO:0051383 kinetochore organization 8.401573e-4
GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway 8.451274e-4
GO:0019452 L-cysteine catabolic process to taurine 8.451274e-4
GO:0003278 apoptosis involved in heart morphogenesis 8.451274e-4
GO:0002885 positive regulation of hypersensitivity 8.860134e-4
GO:0060621 negative regulation of cholesterol import 9.107490e-4
GO:0010035 response to inorganic substance 9.468571e-4
GO:0032909 regulation of transforming growth factor beta2 production 1.008710e-3
GO:0021629 olfactory nerve structural organization 1.085365e-3
GO:0009051 pentose-phosphate shunt, oxidative branch 1.085365e-3
GO:0001710 mesodermal cell fate commitment 1.100057e-3
GO:0006779 porphyrin-containing compound biosynthetic process 1.102583e-3
GO:0033025 regulation of mast cell apoptosis 1.118992e-3
GO:0042149 cellular response to glucose starvation 1.204795e-3
GO:0006270 DNA-dependent DNA replication initiation 1.252753e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.252753e-3
GO:0002540 leukotriene production involved in inflammatory response 1.254343e-3
GO:0071285 cellular response to lithium ion 1.255826e-3
GO:0055085 transmembrane transport 1.256278e-3
GO:0090005 negative regulation of establishment of protein localization in plasma membrane 1.305514e-3
GO:0006432 phenylalanyl-tRNA aminoacylation 1.381893e-3
GO:0034384 high-density lipoprotein particle clearance 1.398673e-3
GO:0050770 regulation of axonogenesis 1.421861e-3
GO:0009113 purine base biosynthetic process 1.429624e-3
GO:0006982 response to lipid hydroperoxide 1.429624e-3
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 1.492799e-3
GO:0015893 drug transport 1.527326e-3
GO:0001977 renal system process involved in regulation of blood volume 1.527424e-3
GO:0072300 positive regulation of metanephric glomerulus development 1.561283e-3
GO:0051353 positive regulation of oxidoreductase activity 1.604539e-3
GO:0070170 regulation of tooth mineralization 1.621044e-3
GO:0060340 positive regulation of type I interferon-mediated signaling pathway 1.647581e-3
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1.649829e-3
GO:0071248 cellular response to metal ion 1.674910e-3
GO:0055117 regulation of cardiac muscle contraction 1.681374e-3
GO:0031334 positive regulation of protein complex assembly 1.715764e-3
GO:0090201 negative regulation of release of cytochrome c from mitochondria 1.728557e-3
GO:0032929 negative regulation of superoxide anion generation 1.736382e-3
GO:0047497 mitochondrion transport along microtubule 1.807772e-3
GO:0042424 catecholamine catabolic process 1.829008e-3
GO:0006659 phosphatidylserine biosynthetic process 1.835567e-3
GO:0046434 organophosphate catabolic process 1.936984e-3
GO:0006625 protein targeting to peroxisome 1.956499e-3
GO:0060339 negative regulation of type I interferon-mediated signaling pathway 2.011025e-3
GO:0070979 protein K11-linked ubiquitination 2.066135e-3
GO:2000378 negative regulation of reactive oxygen species metabolic process 2.068008e-3
GO:0042823 pyridoxal phosphate biosynthetic process 2.106934e-3
GO:0018026 peptidyl-lysine monomethylation 2.119784e-3
GO:0032287 peripheral nervous system myelin maintenance 2.131654e-3
GO:2000017 positive regulation of determination of dorsal identity 2.155744e-3
GO:0034614 cellular response to reactive oxygen species 2.164697e-3
GO:0051668 localization within membrane 2.194667e-3
GO:0035020 regulation of Rac protein signal transduction 2.205259e-3
GO:0001525 angiogenesis 2.239199e-3
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 2.333297e-3
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 2.333297e-3
GO:0010823 negative regulation of mitochondrion organization 2.340932e-3
GO:0009119 ribonucleoside metabolic process 2.346805e-3
GO:0071482 cellular response to light stimulus 2.406159e-3
GO:0051646 mitochondrion localization 2.425766e-3
GO:0042402 cellular biogenic amine catabolic process 2.465097e-3
GO:0046898 response to cycloheximide 2.472273e-3
GO:0045333 cellular respiration 2.505108e-3
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 2.507850e-3
GO:0016338 calcium-independent cell-cell adhesion 2.508683e-3
GO:0046112 nucleobase biosynthetic process 2.510384e-3
GO:0045739 positive regulation of DNA repair 2.629431e-3
GO:0048133 male germ-line stem cell division 2.647128e-3
GO:0071277 cellular response to calcium ion 2.649186e-3
GO:0060435 bronchiole development 2.684079e-3
GO:0060335 positive regulation of interferon-gamma-mediated signaling pathway 2.734037e-3
GO:0033128 negative regulation of histone phosphorylation 2.734037e-3
GO:0006012 galactose metabolic process 2.839680e-3
GO:0043043 peptide biosynthetic process 2.851289e-3
GO:0090187 positive regulation of pancreatic juice secretion 2.876190e-3
GO:0090340 positive regulation of secretion of lysosomal enzymes 2.876190e-3
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA 2.876190e-3
GO:0031118 rRNA pseudouridine synthesis 2.876190e-3
GO:0090108 positive regulation of high-density lipoprotein particle assembly 2.876190e-3
GO:0048013 ephrin receptor signaling pathway 2.884989e-3
GO:0045799 positive regulation of chromatin assembly or disassembly 2.888917e-3
GO:0060217 hemangioblast cell differentiation 2.888917e-3
GO:0046038 GMP catabolic process 2.888917e-3
GO:0032264 IMP salvage 2.888917e-3
GO:0006178 guanine salvage 2.888917e-3
GO:0032263 GMP salvage 2.888917e-3
GO:0060154 cellular process regulating host cell cycle in response to virus 2.933891e-3
GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S 2.939676e-3
GO:0002318 myeloid progenitor cell differentiation 2.939676e-3
GO:0006493 protein O-linked glycosylation 2.999542e-3
GO:0021895 cerebral cortex neuron differentiation 3.031121e-3
GO:0006661 phosphatidylinositol biosynthetic process 3.088278e-3
GO:0045414 regulation of interleukin-8 biosynthetic process 3.168565e-3
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 3.216650e-3
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 3.244172e-3
GO:0016042 lipid catabolic process 3.263511e-3
GO:0043217 myelin maintenance 3.277215e-3
GO:0034442 regulation of lipoprotein oxidation 3.277215e-3
GO:0070995 NADPH oxidation 3.280162e-3
GO:0010226 response to lithium ion 3.387353e-3
GO:0035634 response to stilbenoid 3.440076e-3
GO:0006879 cellular iron ion homeostasis 3.472906e-3
GO:0006168 adenine salvage 3.485792e-3
GO:0023021 termination of signal transduction 3.695677e-3
GO:0051541 elastin metabolic process 3.754044e-3
GO:0045646 regulation of erythrocyte differentiation 3.772312e-3
GO:0046128 purine ribonucleoside metabolic process 3.782828e-3
GO:0051654 establishment of mitochondrion localization 3.814483e-3
GO:0046709 IDP catabolic process 3.875445e-3
GO:0046032 ADP catabolic process 3.875445e-3
GO:0006177 GMP biosynthetic process 3.875445e-3
GO:0071241 cellular response to inorganic substance 3.881240e-3
GO:0032863 activation of Rac GTPase activity 3.948239e-3
GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 3.948239e-3
GO:0002739 regulation of cytokine secretion involved in immune response 3.966643e-3
GO:0015938 coenzyme A catabolic process 3.996694e-3
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 3.996694e-3
GO:0009589 detection of UV 3.996694e-3
GO:0006756 AMP phosphorylation 3.996694e-3
GO:0071456 cellular response to hypoxia 4.018652e-3
GO:0055090 acylglycerol homeostasis 4.021239e-3
GO:0051188 cofactor biosynthetic process 4.159450e-3
GO:0033194 response to hydroperoxide 4.266385e-3
GO:0016973 poly(A)+ mRNA export from nucleus 4.298714e-3
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 4.375118e-3
GO:0015936 coenzyme A metabolic process 4.470156e-3
GO:0032755 positive regulation of interleukin-6 production 4.497178e-3
GO:0006796 phosphate-containing compound metabolic process 4.525896e-3
GO:0050919 negative chemotaxis 4.571479e-3
GO:0070173 regulation of enamel mineralization 4.583646e-3
GO:0071335 hair follicle cell proliferation 4.583646e-3
GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific 4.583646e-3
GO:0032290 peripheral nervous system myelin formation 4.583646e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 4.583646e-3
GO:0046340 diacylglycerol catabolic process 4.627431e-3
GO:0010639 negative regulation of organelle organization 4.713312e-3
GO:0044058 regulation of digestive system process 4.715703e-3
GO:0044003 modification by symbiont of host morphology or physiology 4.818452e-3
GO:0090193 positive regulation of glomerulus development 4.858847e-3
GO:0009116 nucleoside metabolic process 4.865270e-3
GO:0009060 aerobic respiration 4.908875e-3
GO:0021502 neural fold elevation formation 4.973201e-3
GO:0015816 glycine transport 5.043308e-3
GO:0003093 regulation of glomerular filtration 5.043308e-3
GO:0008652 cellular amino acid biosynthetic process 5.076317e-3
GO:0051205 protein insertion into membrane 5.116561e-3
GO:0007256 activation of JNKK activity 5.227155e-3
GO:0006750 glutathione biosynthetic process 5.252822e-3
GO:0034370 triglyceride-rich lipoprotein particle remodeling 5.277890e-3
GO:0050892 intestinal absorption 5.323026e-3
GO:0055026 negative regulation of cardiac muscle tissue development 5.359605e-3
GO:0006507 GPI anchor release 5.359605e-3
GO:0000147 actin cortical patch assembly 5.359605e-3
GO:0000303 response to superoxide 5.403322e-3
GO:0090199 regulation of release of cytochrome c from mitochondria 5.412077e-3
GO:0006685 sphingomyelin catabolic process 5.414813e-3
GO:0001732 formation of translation initiation complex 5.481449e-3
GO:0032780 negative regulation of ATPase activity 5.481449e-3
GO:0080111 DNA demethylation 5.500662e-3
GO:0002227 innate immune response in mucosa 5.624448e-3
GO:0006166 purine ribonucleoside salvage 5.724189e-3
GO:0007566 embryo implantation 5.784668e-3
GO:0034622 cellular macromolecular complex assembly 5.822933e-3
GO:0003333 amino acid transmembrane transport 5.919375e-3
GO:0019228 regulation of action potential in neuron 5.958457e-3
GO:0021675 nerve development 6.010593e-3
GO:0002883 regulation of hypersensitivity 6.053922e-3
GO:0044243 multicellular organismal catabolic process 6.189261e-3
GO:0048014 Tie receptor signaling pathway 6.196708e-3
GO:0002066 columnar/cuboidal epithelial cell development 6.247289e-3
GO:0033522 histone H2A ubiquitination 6.454904e-3
GO:2000300 regulation of synaptic vesicle exocytosis 6.556770e-3
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 6.617437e-3
GO:0010735 positive regulation of transcription via serum response element binding 6.617437e-3
GO:0032202 telomere assembly 6.617437e-3
GO:0003221 right ventricular cardiac muscle tissue morphogenesis 6.617437e-3
GO:0002069 columnar/cuboidal epithelial cell maturation 6.617437e-3
GO:0016226 iron-sulfur cluster assembly 6.664422e-3
GO:0060338 regulation of type I interferon-mediated signaling pathway 6.812683e-3
GO:0033240 positive regulation of cellular amine metabolic process 6.812683e-3
GO:0035510 DNA dealkylation 6.812683e-3
GO:0032314 regulation of Rac GTPase activity 6.822811e-3
GO:0070988 demethylation 6.843543e-3
GO:0022613 ribonucleoprotein complex biogenesis 6.923462e-3
GO:0060972 left/right pattern formation 6.940499e-3
GO:0071415 cellular response to purine-containing compound 7.001234e-3
GO:0046940 nucleoside monophosphate phosphorylation 7.001234e-3
GO:0060160 negative regulation of dopamine receptor signaling pathway 7.001234e-3
GO:0010756 positive regulation of plasminogen activation 7.042291e-3
GO:0071542 dopaminergic neuron differentiation 7.313552e-3
GO:0045213 neurotransmitter receptor metabolic process 7.332323e-3
GO:0070838 divalent metal ion transport 7.362550e-3
GO:0000165 MAPKKK cascade 7.447838e-3
GO:0070257 positive regulation of mucus secretion 7.476057e-3
GO:0072511 divalent inorganic cation transport 7.583867e-3
GO:0060754 positive regulation of mast cell chemotaxis 7.680942e-3
GO:0045576 mast cell activation 7.934536e-3
GO:0051973 positive regulation of telomerase activity 7.995212e-3
GO:0043951 negative regulation of cAMP-mediated signaling 7.995212e-3
GO:0009253 peptidoglycan catabolic process 7.995212e-3
GO:0070189 kynurenine metabolic process 8.010424e-3
GO:0050748 negative regulation of lipoprotein metabolic process 8.010424e-3
GO:0071453 cellular response to oxygen levels 8.211554e-3
GO:0010039 response to iron ion 8.243952e-3
GO:0071722 detoxification of arsenic-containing substance 8.320140e-3
GO:0002176 male germ cell proliferation 8.320140e-3
GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep 8.320140e-3
GO:0032928 regulation of superoxide anion generation 8.480061e-3
GO:0019695 choline metabolic process 8.553634e-3
GO:0003407 neural retina development 8.569774e-3
GO:0014020 primary neural tube formation 8.658602e-3
GO:0002426 immunoglobulin production in mucosal tissue 8.704233e-3
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 8.731708e-3
GO:0060612 adipose tissue development 8.744714e-3
GO:0046514 ceramide catabolic process 8.751142e-3
GO:0034377 plasma lipoprotein particle assembly 8.839790e-3
GO:0048295 positive regulation of isotype switching to IgE isotypes 8.943266e-3
GO:0045964 positive regulation of dopamine metabolic process 8.943266e-3
GO:0010312 detoxification of zinc ion 8.943266e-3
GO:0045836 positive regulation of meiosis 8.954436e-3
GO:0050996 positive regulation of lipid catabolic process 9.103522e-3
GO:0009161 ribonucleoside monophosphate metabolic process 9.204869e-3
GO:0008202 steroid metabolic process 9.327256e-3
GO:0043089 positive regulation of Cdc42 GTPase activity 9.475246e-3
GO:0046621 negative regulation of organ growth 9.543486e-3
GO:0061088 regulation of sequestering of zinc ion 9.559919e-3
GO:0007565 female pregnancy 9.635413e-3
GO:0045065 cytotoxic T cell differentiation 9.688376e-3
GO:0021783 preganglionic parasympathetic nervous system development 9.913681e-3
GO:0070574 cadmium ion transmembrane transport 1.006948e-2
GO:0010511 regulation of phosphatidylinositol biosynthetic process 1.006948e-2
GO:0045773 positive regulation of axon extension 1.007591e-2
GO:0022011 myelination in peripheral nervous system 1.014996e-2
GO:0009746 response to hexose stimulus 1.017023e-2
GO:0001547 antral ovarian follicle growth 1.026561e-2
GO:0021602 cranial nerve morphogenesis 1.059108e-2
GO:0006406 mRNA export from nucleus 1.061029e-2
GO:0021545 cranial nerve development 1.064880e-2
GO:0006413 translational initiation 1.064880e-2
GO:0070837 dehydroascorbic acid transport 1.075283e-2
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 1.075327e-2
GO:0006942 regulation of striated muscle contraction 1.079641e-2
GO:0051026 chiasma assembly 1.080511e-2
GO:0009411 response to UV 1.082324e-2
GO:0044241 lipid digestion 1.101479e-2
GO:0050772 positive regulation of axonogenesis 1.101586e-2
GO:0015980 energy derivation by oxidation of organic compounds 1.103071e-2
GO:0009749 response to glucose stimulus 1.104390e-2
GO:0050872 white fat cell differentiation 1.109717e-2
GO:0035121 tail morphogenesis 1.111241e-2
GO:0007032 endosome organization 1.111241e-2
GO:0071479 cellular response to ionizing radiation 1.116247e-2
GO:0050830 defense response to Gram-positive bacterium 1.118501e-2
GO:0008089 anterograde axon cargo transport 1.120533e-2
GO:0001830 trophectodermal cell fate commitment 1.120533e-2
GO:0060018 astrocyte fate commitment 1.131971e-2
GO:0035964 COPI-coated vesicle budding 1.132282e-2
GO:0042439 ethanolamine-containing compound metabolic process 1.138602e-2
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 1.154656e-2
GO:0044273 sulfur compound catabolic process 1.154656e-2
GO:0014044 Schwann cell development 1.157890e-2
GO:0034284 response to monosaccharide stimulus 1.166880e-2
GO:0043254 regulation of protein complex assembly 1.185836e-2
GO:0001508 regulation of action potential 1.197492e-2
GO:0002702 positive regulation of production of molecular mediator of immune response 1.201268e-2
GO:0044272 sulfur compound biosynthetic process 1.207412e-2
GO:0006290 pyrimidine dimer repair 1.212198e-2
GO:0008595 anterior/posterior axis specification, embryo 1.221079e-2
GO:0031054 pre-miRNA processing 1.228866e-2
GO:0034380 high-density lipoprotein particle assembly 1.230287e-2
GO:0050848 regulation of calcium-mediated signaling 1.240830e-2
GO:0071260 cellular response to mechanical stimulus 1.269311e-2
GO:0030838 positive regulation of actin filament polymerization 1.280286e-2
GO:0019370 leukotriene biosynthetic process 1.284605e-2
GO:0031100 organ regeneration 1.288068e-2
GO:0007422 peripheral nervous system development 1.292550e-2
GO:0032763 regulation of mast cell cytokine production 1.313737e-2
GO:0019377 glycolipid catabolic process 1.318413e-2
GO:0043173 nucleotide salvage 1.329457e-2
GO:0051643 endoplasmic reticulum localization 1.329457e-2
GO:0021562 vestibulocochlear nerve development 1.329457e-2
GO:0019448 L-cysteine catabolic process 1.329457e-2
GO:0009115 xanthine catabolic process 1.329457e-2
GO:0009154 purine ribonucleotide catabolic process 1.333114e-2
GO:0071480 cellular response to gamma radiation 1.345459e-2
GO:0032228 regulation of synaptic transmission, GABAergic 1.347025e-2
GO:0021603 cranial nerve formation 1.355065e-2
GO:0018106 peptidyl-histidine phosphorylation 1.355065e-2
GO:0000209 protein polyubiquitination 1.375586e-2
GO:0042373 vitamin K metabolic process 1.380487e-2
GO:0035520 monoubiquitinated protein deubiquitination 1.380487e-2
GO:0034059 response to anoxia 1.380487e-2
GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 1.380487e-2
GO:0021527 spinal cord association neuron differentiation 1.388020e-2
GO:0071879 positive regulation of adrenergic receptor signaling pathway 1.391974e-2
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 1.391974e-2
GO:0002730 regulation of dendritic cell cytokine production 1.391974e-2
GO:0045648 positive regulation of erythrocyte differentiation 1.404397e-2
GO:0045647 negative regulation of erythrocyte differentiation 1.411275e-2
GO:0030195 negative regulation of blood coagulation 1.411779e-2
GO:0006778 porphyrin-containing compound metabolic process 1.421760e-2
GO:0001894 tissue homeostasis 1.422725e-2
GO:0006534 cysteine metabolic process 1.441221e-2
GO:0007005 mitochondrion organization 1.453642e-2
GO:0032963 collagen metabolic process 1.454437e-2
GO:0046549 retinal cone cell development 1.466500e-2
GO:0032273 positive regulation of protein polymerization 1.468319e-2
GO:0006144 purine base metabolic process 1.469591e-2
GO:0006000 fructose metabolic process 1.469591e-2
GO:0045454 cell redox homeostasis 1.474783e-2
GO:0032862 activation of Rho GTPase activity 1.486052e-2
GO:2000015 regulation of determination of dorsal identity 1.494636e-2
GO:0006705 mineralocorticoid biosynthetic process 1.494636e-2
GO:0006283 transcription-coupled nucleotide-excision repair 1.494636e-2
GO:0006027 glycosaminoglycan catabolic process 1.494636e-2
GO:0060047 heart contraction 1.497030e-2
GO:0048706 embryonic skeletal system development 1.499265e-2
GO:0042391 regulation of membrane potential 1.507840e-2
GO:0090150 establishment of protein localization in membrane 1.509591e-2
GO:0045010 actin nucleation 1.509591e-2
GO:0043101 purine-containing compound salvage 1.509591e-2
GO:0042278 purine nucleoside metabolic process 1.527912e-2
GO:0051129 negative regulation of cellular component organization 1.540685e-2
GO:0043096 purine base salvage 1.548515e-2
GO:0035566 regulation of metanephros size 1.548515e-2
GO:0043306 positive regulation of mast cell degranulation 1.557125e-2
GO:0070541 response to platinum ion 1.557125e-2
GO:0006658 phosphatidylserine metabolic process 1.557125e-2
GO:0050808 synapse organization 1.563308e-2
GO:0090287 regulation of cellular response to growth factor stimulus 1.577055e-2
GO:0015914 phospholipid transport 1.585493e-2
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 1.588679e-2
GO:0045217 cell-cell junction maintenance 1.588679e-2
GO:0030157 pancreatic juice secretion 1.588679e-2
GO:0032439 endosome localization 1.604822e-2
GO:0015993 molecular hydrogen transport 1.604822e-2
GO:0046394 carboxylic acid biosynthetic process 1.606017e-2
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1.608556e-2
GO:0060998 regulation of dendritic spine development 1.611233e-2
GO:0018022 peptidyl-lysine methylation 1.611819e-2
GO:0042133 neurotransmitter metabolic process 1.657494e-2
GO:0006816 calcium ion transport 1.659923e-2
GO:0031398 positive regulation of protein ubiquitination 1.663027e-2
GO:0044332 Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.675709e-2
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine 1.675709e-2
GO:0035524 proline transmembrane transport 1.676241e-2
GO:0046479 glycosphingolipid catabolic process 1.676241e-2
GO:0019054 modulation by virus of host cellular process 1.679809e-2
GO:0021700 developmental maturation 1.682761e-2
GO:0033700 phospholipid efflux 1.685604e-2
GO:0048676 axon extension involved in development 1.698894e-2
GO:0034655 nucleobase-containing compound catabolic process 1.701901e-2
GO:0001961 positive regulation of cytokine-mediated signaling pathway 1.716925e-2
GO:0009395 phospholipid catabolic process 1.721004e-2
GO:0002720 positive regulation of cytokine production involved in immune response 1.729544e-2
GO:0021563 glossopharyngeal nerve development 1.732352e-2
GO:0050771 negative regulation of axonogenesis 1.742881e-2
GO:0015804 neutral amino acid transport 1.764186e-2
GO:0072523 purine-containing compound catabolic process 1.794769e-2