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Novel motif:15

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name:motif15_ACTGTG

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0050896 response to stimulus 5.592997e-53
GO:0006952 defense response 1.520086e-38
GO:0002376 immune system process 1.109067e-36
GO:0006955 immune response 5.066833e-35
GO:0065007 biological regulation 3.827205e-32
GO:0051716 cellular response to stimulus 4.978166e-32
GO:0050789 regulation of biological process 2.460384e-31
GO:0007154 cell communication 2.404335e-27
GO:0023052 signaling 1.044851e-26
GO:0009607 response to biotic stimulus 1.830498e-26
GO:0007165 signal transduction 7.464532e-26
GO:0006950 response to stress 2.163656e-25
GO:0032501 multicellular organismal process 3.653145e-25
GO:0048583 regulation of response to stimulus 1.719428e-24
GO:0051707 response to other organism 2.506841e-24
GO:0050794 regulation of cellular process 4.420804e-24
GO:0006954 inflammatory response 6.375586e-24
GO:0045087 innate immune response 1.737259e-23
GO:0009987 cellular process 1.554986e-22
GO:0009617 response to bacterium 8.821971e-20
GO:0007166 cell surface receptor linked signaling pathway 2.596457e-19
GO:0002253 activation of immune response 2.687795e-19
GO:0002684 positive regulation of immune system process 4.843380e-19
GO:0042221 response to chemical stimulus 1.451304e-18
GO:0050778 positive regulation of immune response 1.591989e-18
GO:0009611 response to wounding 1.759903e-18
GO:0002237 response to molecule of bacterial origin 2.126819e-18
GO:0051704 multi-organism process 3.390066e-18
GO:0032496 response to lipopolysaccharide 8.737480e-18
GO:0002682 regulation of immune system process 9.295317e-18
GO:0065008 regulation of biological quality 1.748857e-17
GO:0044281 small molecule metabolic process 9.136719e-17
GO:0051234 establishment of localization 1.250287e-16
GO:0006810 transport 2.219442e-16
GO:0050776 regulation of immune response 2.384622e-16
GO:0048584 positive regulation of response to stimulus 2.592334e-16
GO:0032879 regulation of localization 4.359031e-16
GO:0080134 regulation of response to stress 8.019677e-16
GO:0010033 response to organic substance 8.127683e-16
GO:0009628 response to abiotic stimulus 2.149006e-15
GO:0002757 immune response-activating signal transduction 2.640269e-15
GO:0001775 cell activation 3.790843e-15
GO:0051179 localization 4.673477e-15
GO:0002764 immune response-regulating signaling pathway 4.684345e-15
GO:0008152 metabolic process 5.542588e-15
GO:0048518 positive regulation of biological process 1.353862e-14
GO:0051050 positive regulation of transport 1.446240e-14
GO:0032502 developmental process 5.241326e-14
GO:0045321 leukocyte activation 8.102961e-14
GO:0007155 cell adhesion 2.009774e-13
GO:0051049 regulation of transport 2.517738e-13
GO:0006968 cellular defense response 2.648075e-13
GO:0006725 cellular aromatic compound metabolic process 3.837363e-13
GO:0051239 regulation of multicellular organismal process 9.773619e-13
GO:0042592 homeostatic process 2.510801e-12
GO:0048519 negative regulation of biological process 3.342593e-12
GO:0006875 cellular metal ion homeostasis 4.135951e-12
GO:0030003 cellular cation homeostasis 4.964352e-12
GO:0006629 lipid metabolic process 6.047559e-12
GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport 6.361953e-12
GO:0055065 metal ion homeostasis 7.133176e-12
GO:2000021 regulation of ion homeostasis 7.517181e-12
GO:0042326 negative regulation of phosphorylation 7.755772e-12
GO:0016192 vesicle-mediated transport 8.186196e-12
GO:0051240 positive regulation of multicellular organismal process 9.829713e-12
GO:0048856 anatomical structure development 1.103715e-11
GO:0042446 hormone biosynthetic process 1.121899e-11
GO:0045936 negative regulation of phosphate metabolic process 1.162701e-11
GO:0031347 regulation of defense response 1.651582e-11
GO:0019538 protein metabolic process 1.696928e-11
GO:0009268 response to pH 1.953531e-11
GO:0030799 regulation of cyclic nucleotide metabolic process 2.102528e-11
GO:0032844 regulation of homeostatic process 2.251003e-11
GO:0071840 cellular component organization or biogenesis 2.608373e-11
GO:0010646 regulation of cell communication 2.704445e-11
GO:0007267 cell-cell signaling 2.792441e-11
GO:0030802 regulation of cyclic nucleotide biosynthetic process 3.077876e-11
GO:0007186 G-protein coupled receptor protein signaling pathway 3.087802e-11
GO:0034097 response to cytokine stimulus 3.511621e-11
GO:0031295 T cell costimulation 5.353136e-11
GO:0007275 multicellular organismal development 5.656125e-11
GO:0031279 regulation of cyclase activity 6.520658e-11
GO:0051223 regulation of protein transport 7.206424e-11
GO:0070887 cellular response to chemical stimulus 8.347502e-11
GO:0044106 cellular amine metabolic process 1.020555e-10
GO:0006873 cellular ion homeostasis 1.063536e-10
GO:0051339 regulation of lyase activity 1.159749e-10
GO:0016043 cellular component organization 1.170303e-10
GO:0023051 regulation of signaling 1.173670e-10
GO:0060333 interferon-gamma-mediated signaling pathway 1.567693e-10
GO:0032940 secretion by cell 1.984712e-10
GO:0071222 cellular response to lipopolysaccharide 3.253512e-10
GO:0046649 lymphocyte activation 3.957840e-10
GO:0046777 protein autophosphorylation 4.873647e-10
GO:0009966 regulation of signal transduction 5.962137e-10
GO:0030814 regulation of cAMP metabolic process 6.002084e-10
GO:0048523 negative regulation of cellular process 6.399150e-10
GO:0031641 regulation of myelination 7.501352e-10
GO:0031663 lipopolysaccharide-mediated signaling pathway 9.803280e-10
GO:0055082 cellular chemical homeostasis 1.018084e-9
GO:0045056 transcytosis 1.105998e-9
GO:0019725 cellular homeostasis 1.254631e-9
GO:0071346 cellular response to interferon-gamma 1.335618e-9
GO:0071219 cellular response to molecule of bacterial origin 1.430382e-9
GO:0009308 amine metabolic process 1.505489e-9
GO:0071216 cellular response to biotic stimulus 1.598862e-9
GO:0006066 alcohol metabolic process 1.839431e-9
GO:0048513 organ development 2.289595e-9
GO:0002576 platelet degranulation 2.480070e-9
GO:0048878 chemical homeostasis 2.482421e-9
GO:0050801 ion homeostasis 2.627277e-9
GO:0006869 lipid transport 2.728669e-9
GO:0072376 protein activation cascade 2.777856e-9
GO:0014057 positive regulation of acetylcholine secretion 2.885635e-9
GO:0008202 steroid metabolic process 3.130218e-9
GO:0030817 regulation of cAMP biosynthetic process 3.153836e-9
GO:0045761 regulation of adenylate cyclase activity 3.276336e-9
GO:0042060 wound healing 3.309803e-9
GO:0046903 secretion 3.463574e-9
GO:0006468 protein phosphorylation 3.995533e-9
GO:0055080 cation homeostasis 4.403811e-9
GO:0035815 positive regulation of renal sodium excretion 4.713133e-9
GO:0003008 system process 4.912746e-9
GO:0002429 immune response-activating cell surface receptor signaling pathway 4.996164e-9
GO:0032880 regulation of protein localization 5.620472e-9
GO:0019752 carboxylic acid metabolic process 5.719185e-9
GO:0051248 negative regulation of protein metabolic process 5.907749e-9
GO:0042180 cellular ketone metabolic process 6.481782e-9
GO:0001817 regulation of cytokine production 6.686179e-9
GO:0070201 regulation of establishment of protein localization 6.757145e-9
GO:0002768 immune response-regulating cell surface receptor signaling pathway 7.315546e-9
GO:0050852 T cell receptor signaling pathway 8.372658e-9
GO:0018958 phenol-containing compound metabolic process 8.726151e-9
GO:0072503 cellular divalent inorganic cation homeostasis 8.868608e-9
GO:0009063 cellular amino acid catabolic process 1.053873e-8
GO:0048522 positive regulation of cellular process 1.164867e-8
GO:0043412 macromolecule modification 1.295085e-8
GO:0050793 regulation of developmental process 1.383660e-8
GO:0006082 organic acid metabolic process 1.386143e-8
GO:0048143 astrocyte activation 1.437285e-8
GO:0010817 regulation of hormone levels 1.701961e-8
GO:0051349 positive regulation of lyase activity 1.715803e-8
GO:0006959 humoral immune response 1.744286e-8
GO:0034341 response to interferon-gamma 1.819496e-8
GO:0046395 carboxylic acid catabolic process 1.924995e-8
GO:0045088 regulation of innate immune response 2.018468e-8
GO:0045089 positive regulation of innate immune response 2.018784e-8
GO:0009266 response to temperature stimulus 2.086401e-8
GO:0042445 hormone metabolic process 2.179791e-8
GO:0044238 primary metabolic process 2.195061e-8
GO:0009310 amine catabolic process 2.356998e-8
GO:0035810 positive regulation of urine volume 2.465487e-8
GO:0009888 tissue development 2.718080e-8
GO:0042403 thyroid hormone metabolic process 2.767325e-8
GO:0031349 positive regulation of defense response 2.900735e-8
GO:0002221 pattern recognition receptor signaling pathway 3.133357e-8
GO:0002758 innate immune response-activating signal transduction 3.197503e-8
GO:0031281 positive regulation of cyclase activity 3.287563e-8
GO:0034762 regulation of transmembrane transport 3.521164e-8
GO:0048731 system development 3.641915e-8
GO:0043067 regulation of programmed cell death 3.964210e-8
GO:0006590 thyroid hormone generation 4.018244e-8
GO:0006520 cellular amino acid metabolic process 4.228015e-8
GO:0001933 negative regulation of protein phosphorylation 4.317327e-8
GO:0010941 regulation of cell death 4.722099e-8
GO:0042537 benzene-containing compound metabolic process 4.902037e-8
GO:0035093 spermatogenesis, exchange of chromosomal proteins 5.539507e-8
GO:0042127 regulation of cell proliferation 5.610094e-8
GO:0072507 divalent inorganic cation homeostasis 5.616640e-8
GO:0042981 regulation of apoptosis 5.806626e-8
GO:0002218 activation of innate immune response 6.487849e-8
GO:0014002 astrocyte development 6.491097e-8
GO:0050900 leukocyte migration 6.546443e-8
GO:0031099 regeneration 6.725635e-8
GO:0065009 regulation of molecular function 7.017907e-8
GO:0016310 phosphorylation 7.295923e-8
GO:0044255 cellular lipid metabolic process 7.661725e-8
GO:0051128 regulation of cellular component organization 7.800261e-8
GO:0006874 cellular calcium ion homeostasis 7.988578e-8
GO:0009605 response to external stimulus 9.558286e-8
GO:0006464 protein modification process 9.944012e-8
GO:0010876 lipid localization 1.023931e-7
GO:0009056 catabolic process 1.117176e-7
GO:0014056 regulation of acetylcholine secretion 1.152991e-7
GO:0010756 positive regulation of plasminogen activation 1.279324e-7
GO:0002694 regulation of leukocyte activation 1.312199e-7
GO:0006887 exocytosis 1.381461e-7
GO:0051222 positive regulation of protein transport 1.393755e-7
GO:0007190 activation of adenylate cyclase activity 1.439663e-7
GO:0050708 regulation of protein secretion 1.463885e-7
GO:0055074 calcium ion homeostasis 1.589393e-7
GO:0006956 complement activation 1.600182e-7
GO:0060341 regulation of cellular localization 1.869387e-7
GO:0006554 lysine catabolic process 1.874658e-7
GO:0045762 positive regulation of adenylate cyclase activity 1.940612e-7
GO:0006796 phosphate-containing compound metabolic process 1.951068e-7
GO:0050865 regulation of cell activation 2.112201e-7
GO:0050863 regulation of T cell activation 2.622199e-7
GO:0007599 hemostasis 2.774829e-7
GO:0007596 blood coagulation 2.888943e-7
GO:0050878 regulation of body fluid levels 3.014101e-7
GO:0071345 cellular response to cytokine stimulus 3.155759e-7
GO:0002526 acute inflammatory response 3.209521e-7
GO:0015705 iodide transport 3.332483e-7
GO:0048585 negative regulation of response to stimulus 3.428078e-7
GO:0071702 organic substance transport 3.450248e-7
GO:0002522 leukocyte migration involved in immune response 3.708543e-7
GO:0016064 immunoglobulin mediated immune response 3.768238e-7
GO:0009408 response to heat 4.161706e-7
GO:0002252 immune effector process 4.173310e-7
GO:0002885 positive regulation of hypersensitivity 4.328504e-7
GO:0031000 response to caffeine 4.362900e-7
GO:0071310 cellular response to organic substance 4.552118e-7
GO:0046486 glycerolipid metabolic process 4.747019e-7
GO:0008063 Toll signaling pathway 4.931343e-7
GO:0051249 regulation of lymphocyte activation 4.938948e-7
GO:0043068 positive regulation of programmed cell death 4.944732e-7
GO:0042098 T cell proliferation 5.012918e-7
GO:0050877 neurological system process 5.112845e-7
GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway 5.214508e-7
GO:0032680 regulation of tumor necrosis factor production 5.236146e-7
GO:0002883 regulation of hypersensitivity 5.390567e-7
GO:0006306 DNA methylation 5.600351e-7
GO:0050851 antigen receptor-mediated signaling pathway 5.714925e-7
GO:0050819 negative regulation of coagulation 6.149608e-7
GO:0044092 negative regulation of molecular function 6.379305e-7
GO:0009725 response to hormone stimulus 6.466096e-7
GO:0060249 anatomical structure homeostasis 6.800234e-7
GO:0001819 positive regulation of cytokine production 6.982185e-7
GO:0034446 substrate adhesion-dependent cell spreading 7.001229e-7
GO:0051384 response to glucocorticoid stimulus 7.105884e-7
GO:0051024 positive regulation of immunoglobulin secretion 7.256555e-7
GO:0010942 positive regulation of cell death 7.770064e-7
GO:0050867 positive regulation of cell activation 7.781548e-7
GO:0030168 platelet activation 7.995378e-7
GO:0044282 small molecule catabolic process 7.996877e-7
GO:0002443 leukocyte mediated immunity 8.088413e-7
GO:0019722 calcium-mediated signaling 8.193767e-7
GO:0051047 positive regulation of secretion 8.205838e-7
GO:0010743 regulation of macrophage derived foam cell differentiation 8.222888e-7
GO:0001963 synaptic transmission, dopaminergic 8.655034e-7
GO:0010874 regulation of cholesterol efflux 9.877070e-7
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 1.012227e-6
GO:0002755 MyD88-dependent toll-like receptor signaling pathway 1.021453e-6
GO:0002696 positive regulation of leukocyte activation 1.041865e-6
GO:0006570 tyrosine metabolic process 1.043428e-6
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway 1.060892e-6
GO:0034381 plasma lipoprotein particle clearance 1.068800e-6
GO:0035809 regulation of urine volume 1.099558e-6
GO:0019226 transmission of nerve impulse 1.107327e-6
GO:0050870 positive regulation of T cell activation 1.146873e-6
GO:0006572 tyrosine catabolic process 1.166944e-6
GO:0044093 positive regulation of molecular function 1.170688e-6
GO:0032374 regulation of cholesterol transport 1.217971e-6
GO:0030595 leukocyte chemotaxis 1.241427e-6
GO:0010466 negative regulation of peptidase activity 1.281445e-6
GO:0009746 response to hexose stimulus 1.349092e-6
GO:0071841 cellular component organization or biogenesis at cellular level 1.371816e-6
GO:0043065 positive regulation of apoptosis 1.417375e-6
GO:0002224 toll-like receptor signaling pathway 1.421685e-6
GO:0052547 regulation of peptidase activity 1.572130e-6
GO:0034134 toll-like receptor 2 signaling pathway 1.575745e-6
GO:0034130 toll-like receptor 1 signaling pathway 1.575745e-6
GO:0007271 synaptic transmission, cholinergic 1.742841e-6
GO:0031647 regulation of protein stability 1.773721e-6
GO:0044062 regulation of excretion 1.794697e-6
GO:0009581 detection of external stimulus 1.794720e-6
GO:0016337 cell-cell adhesion 1.839322e-6
GO:0009749 response to glucose stimulus 1.901004e-6
GO:0042110 T cell activation 1.962282e-6
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2.009283e-6
GO:0034138 toll-like receptor 3 signaling pathway 2.087233e-6
GO:0051606 detection of stimulus 2.137474e-6
GO:0051649 establishment of localization in cell 2.270195e-6
GO:0032230 positive regulation of synaptic transmission, GABAergic 2.296440e-6
GO:0051241 negative regulation of multicellular organismal process 2.374879e-6
GO:0021544 subpallium development 2.421739e-6
GO:0006909 phagocytosis 2.449847e-6
GO:0007597 blood coagulation, intrinsic pathway 2.543972e-6
GO:0044248 cellular catabolic process 2.701476e-6
GO:0034142 toll-like receptor 4 signaling pathway 2.854894e-6
GO:0071842 cellular component organization at cellular level 2.928632e-6
GO:0010647 positive regulation of cell communication 3.011673e-6
GO:0006915 apoptosis 3.038000e-6
GO:0019724 B cell mediated immunity 3.108211e-6
GO:0006897 endocytosis 3.291777e-6
GO:0019932 second-messenger-mediated signaling 3.423147e-6
GO:0009968 negative regulation of signal transduction 3.466727e-6
GO:0051046 regulation of secretion 3.517482e-6
GO:0009719 response to endogenous stimulus 3.552953e-6
GO:0007525 somatic muscle development 3.607350e-6
GO:0097006 regulation of plasma lipoprotein particle levels 3.651311e-6
GO:2000026 regulation of multicellular organismal development 3.651656e-6
GO:0043114 regulation of vascular permeability 3.716322e-6
GO:0034284 response to monosaccharide stimulus 3.816313e-6
GO:0046634 regulation of alpha-beta T cell activation 4.062277e-6
GO:0007268 synaptic transmission 4.138329e-6
GO:0051251 positive regulation of lymphocyte activation 4.183119e-6
GO:0002756 MyD88-independent toll-like receptor signaling pathway 4.191991e-6
GO:0035813 regulation of renal sodium excretion 4.233370e-6
GO:0043116 negative regulation of vascular permeability 4.436703e-6
GO:0030277 maintenance of gastrointestinal epithelium 4.659937e-6
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 4.814930e-6
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 4.824325e-6
GO:0006958 complement activation, classical pathway 4.829669e-6
GO:0031100 organ regeneration 4.914399e-6
GO:0043086 negative regulation of catalytic activity 4.969342e-6
GO:0009744 response to sucrose stimulus 5.663613e-6
GO:0009156 ribonucleoside monophosphate biosynthetic process 5.789571e-6
GO:0021756 striatum development 5.866212e-6
GO:0010648 negative regulation of cell communication 5.895354e-6
GO:0044237 cellular metabolic process 5.950366e-6
GO:0012501 programmed cell death 6.196355e-6
GO:0001959 regulation of cytokine-mediated signaling pathway 6.220323e-6
GO:0060074 synapse maturation 6.367646e-6
GO:0009629 response to gravity 6.413427e-6
GO:0023057 negative regulation of signaling 6.464818e-6
GO:0051480 cytosolic calcium ion homeostasis 6.527864e-6
GO:0023056 positive regulation of signaling 6.956821e-6
GO:0000266 mitochondrial fission 7.014181e-6
GO:0051023 regulation of immunoglobulin secretion 7.228269e-6
GO:0018904 organic ether metabolic process 7.581682e-6
GO:0045343 regulation of MHC class I biosynthetic process 7.888102e-6
GO:0019439 aromatic compound catabolic process 8.107687e-6
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 8.117643e-6
GO:0045730 respiratory burst 8.149214e-6
GO:0006916 anti-apoptosis 8.301150e-6
GO:0032101 regulation of response to external stimulus 8.323983e-6
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 8.512761e-6
GO:0006914 autophagy 8.618801e-6
GO:0048660 regulation of smooth muscle cell proliferation 9.061908e-6
GO:0040011 locomotion 9.139109e-6
GO:0050821 protein stabilization 9.539709e-6
GO:0002455 humoral immune response mediated by circulating immunoglobulin 9.709054e-6
GO:0001973 adenosine receptor signaling pathway 9.968800e-6
GO:0009048 dosage compensation, by inactivation of X chromosome 1.007707e-5
GO:0051968 positive regulation of synaptic transmission, glutamatergic 1.037090e-5
GO:0031098 stress-activated protein kinase signaling cascade 1.080027e-5
GO:0045346 regulation of MHC class II biosynthetic process 1.097613e-5
GO:2000507 positive regulation of energy homeostasis 1.116104e-5
GO:2000253 positive regulation of feeding behavior 1.116104e-5
GO:0014074 response to purine-containing compound 1.128947e-5
GO:0050709 negative regulation of protein secretion 1.129994e-5
GO:0019221 cytokine-mediated signaling pathway 1.137173e-5
GO:0009582 detection of abiotic stimulus 1.238945e-5
GO:0060821 inactivation of X chromosome by DNA methylation 1.260089e-5
GO:0034764 positive regulation of transmembrane transport 1.283856e-5
GO:0015698 inorganic anion transport 1.309000e-5
GO:0060759 regulation of response to cytokine stimulus 1.319472e-5
GO:0002274 myeloid leukocyte activation 1.336084e-5
GO:0021782 glial cell development 1.346805e-5
GO:0007204 elevation of cytosolic calcium ion concentration 1.368322e-5
GO:0014049 positive regulation of glutamate secretion 1.371096e-5
GO:0051224 negative regulation of protein transport 1.379837e-5
GO:0071286 cellular response to magnesium ion 1.433193e-5
GO:0032370 positive regulation of lipid transport 1.446444e-5
GO:0035556 intracellular signal transduction 1.454350e-5
GO:0051403 stress-activated MAPK cascade 1.466209e-5
GO:0009112 nucleobase metabolic process 1.494079e-5
GO:0009068 aspartate family amino acid catabolic process 1.532223e-5
GO:0008610 lipid biosynthetic process 1.599336e-5
GO:0008037 cell recognition 1.609465e-5
GO:0033157 regulation of intracellular protein transport 1.628782e-5
GO:0035092 sperm chromatin condensation 1.631306e-5
GO:0019222 regulation of metabolic process 1.752462e-5
GO:0044419 interspecies interaction between organisms 1.779230e-5
GO:0006662 glycerol ether metabolic process 1.823455e-5
GO:0032870 cellular response to hormone stimulus 1.944328e-5
GO:0006953 acute-phase response 1.995242e-5
GO:0046483 heterocycle metabolic process 2.001561e-5
GO:0006576 cellular biogenic amine metabolic process 2.013546e-5
GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 2.052789e-5
GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2.065771e-5
GO:0042119 neutrophil activation 2.102405e-5
GO:0009066 aspartate family amino acid metabolic process 2.151760e-5
GO:0032534 regulation of microvillus assembly 2.197549e-5
GO:0032735 positive regulation of interleukin-12 production 2.225774e-5
GO:0070101 positive regulation of chemokine-mediated signaling pathway 2.233255e-5
GO:0032368 regulation of lipid transport 2.243857e-5
GO:0042176 regulation of protein catabolic process 2.265833e-5
GO:0010669 epithelial structure maintenance 2.328563e-5
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 2.355074e-5
GO:0045834 positive regulation of lipid metabolic process 2.381501e-5
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 2.606416e-5
GO:0010883 regulation of lipid storage 2.606416e-5
GO:0006559 L-phenylalanine catabolic process 2.610034e-5
GO:0070099 regulation of chemokine-mediated signaling pathway 2.637168e-5
GO:0032269 negative regulation of cellular protein metabolic process 2.656188e-5
GO:0043269 regulation of ion transport 2.801119e-5
GO:0046600 negative regulation of centriole replication 2.996577e-5
GO:0050707 regulation of cytokine secretion 3.000094e-5
GO:0045348 positive regulation of MHC class II biosynthetic process 3.022840e-5
GO:0001956 positive regulation of neurotransmitter secretion 3.049763e-5
GO:0010875 positive regulation of cholesterol efflux 3.163581e-5
GO:0042325 regulation of phosphorylation 3.260405e-5
GO:0008211 glucocorticoid metabolic process 3.500568e-5
GO:0001812 positive regulation of type I hypersensitivity 3.501294e-5
GO:0035058 nonmotile primary cilium assembly 3.509418e-5
GO:0006575 cellular modified amino acid metabolic process 3.638453e-5
GO:0007194 negative regulation of adenylate cyclase activity 3.645471e-5
GO:0002407 dendritic cell chemotaxis 3.726804e-5
GO:0006664 glycolipid metabolic process 3.786036e-5
GO:0046638 positive regulation of alpha-beta T cell differentiation 3.836709e-5
GO:0006639 acylglycerol metabolic process 3.843615e-5
GO:0032570 response to progesterone stimulus 3.857526e-5
GO:0034330 cell junction organization 4.025442e-5
GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway 4.055448e-5
GO:0048871 multicellular organismal homeostasis 4.061438e-5
GO:0046822 regulation of nucleocytoplasmic transport 4.069660e-5
GO:0072593 reactive oxygen species metabolic process 4.097816e-5
GO:0007631 feeding behavior 4.101734e-5
GO:0007050 cell cycle arrest 4.101937e-5
GO:0020027 hemoglobin metabolic process 4.127564e-5
GO:0035295 tube development 4.155432e-5
GO:0032966 negative regulation of collagen biosynthetic process 4.166859e-5
GO:0032386 regulation of intracellular transport 4.231909e-5
GO:0032655 regulation of interleukin-12 production 4.338548e-5
GO:0045345 positive regulation of MHC class I biosynthetic process 4.360647e-5
GO:0044267 cellular protein metabolic process 4.480446e-5
GO:0052548 regulation of endopeptidase activity 4.513774e-5
GO:0006641 triglyceride metabolic process 4.557912e-5
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 4.654268e-5
GO:0048468 cell development 4.673298e-5
GO:0043558 regulation of translational initiation in response to stress 4.675855e-5
GO:0043304 regulation of mast cell degranulation 4.819031e-5
GO:0030832 regulation of actin filament length 4.849786e-5
GO:0009967 positive regulation of signal transduction 4.872330e-5
GO:0031946 regulation of glucocorticoid biosynthetic process 5.050812e-5
GO:0072358 cardiovascular system development 5.111260e-5
GO:0031282 regulation of guanylate cyclase activity 5.207708e-5
GO:0051094 positive regulation of developmental process 5.369675e-5
GO:0042541 hemoglobin biosynthetic process 5.393824e-5
GO:0010869 regulation of receptor biosynthetic process 5.482379e-5
GO:0006144 purine base metabolic process 5.489958e-5
GO:0042306 regulation of protein import into nucleus 5.519688e-5
GO:0050727 regulation of inflammatory response 5.528867e-5
GO:0046548 retinal rod cell development 5.565221e-5
GO:0010038 response to metal ion 5.600481e-5
GO:0051588 regulation of neurotransmitter transport 5.626758e-5
GO:0009615 response to virus 5.765241e-5
GO:0009100 glycoprotein metabolic process 5.817515e-5
GO:0035413 positive regulation of catenin import into nucleus 5.822834e-5
GO:0046700 heterocycle catabolic process 5.860549e-5
GO:0016098 monoterpenoid metabolic process 6.320054e-5
GO:0032736 positive regulation of interleukin-13 production 6.337362e-5
GO:0051346 negative regulation of hydrolase activity 6.388095e-5
GO:0045444 fat cell differentiation 6.432698e-5
GO:0006508 proteolysis 6.482817e-5
GO:0009161 ribonucleoside monophosphate metabolic process 6.505495e-5
GO:0040012 regulation of locomotion 6.508959e-5
GO:0070723 response to cholesterol 6.591438e-5
GO:0015671 oxygen transport 6.596227e-5
GO:0071241 cellular response to inorganic substance 6.620765e-5
GO:2000534 positive regulation of renal albumin absorption 7.036017e-5
GO:0070994 detection of oxidative stress 7.036017e-5
GO:2000481 positive regulation of cAMP-dependent protein kinase activity 7.036017e-5
GO:2000461 negative regulation of eukaryotic cell surface binding 7.036017e-5
GO:2000478 positive regulation of metanephric glomerular visceral epithelial cell development 7.036017e-5
GO:0045767 regulation of anti-apoptosis 7.058333e-5
GO:0032720 negative regulation of tumor necrosis factor production 7.070273e-5
GO:0034329 cell junction assembly 7.306655e-5
GO:0032530 regulation of microvillus organization 7.502400e-5
GO:0032376 positive regulation of cholesterol transport 7.530005e-5
GO:0033006 regulation of mast cell activation involved in immune response 7.583262e-5
GO:0046824 positive regulation of nucleocytoplasmic transport 7.659170e-5
GO:0042742 defense response to bacterium 7.693863e-5
GO:0019216 regulation of lipid metabolic process 8.066820e-5
GO:0002430 complement receptor mediated signaling pathway 8.067580e-5
GO:0050710 negative regulation of cytokine secretion 8.575367e-5
GO:0001960 negative regulation of cytokine-mediated signaling pathway 9.042270e-5
GO:0030325 adrenal gland development 9.074967e-5
GO:0003417 growth plate cartilage development 9.112014e-5
GO:0001894 tissue homeostasis 9.193011e-5
GO:0031348 negative regulation of defense response 9.264400e-5
GO:0032494 response to peptidoglycan 9.431068e-5
GO:0090208 positive regulation of triglyceride metabolic process 9.481294e-5
GO:0007626 locomotory behavior 9.555473e-5
GO:0043402 glucocorticoid mediated signaling pathway 9.647668e-5
GO:0030522 intracellular receptor mediated signaling pathway 9.725327e-5
GO:0032350 regulation of hormone metabolic process 9.878659e-5
GO:0035588 G-protein coupled purinergic receptor signaling pathway 9.884582e-5
GO:0030154 cell differentiation 9.922041e-5
GO:0051350 negative regulation of lyase activity 1.027154e-4
GO:0009249 protein lipoylation 1.036476e-4
GO:0006638 neutral lipid metabolic process 1.056478e-4
GO:0046928 regulation of neurotransmitter secretion 1.068407e-4
GO:0002355 detection of tumor cell 1.079853e-4
GO:0051412 response to corticosterone stimulus 1.098945e-4
GO:0050818 regulation of coagulation 1.102360e-4
GO:0048732 gland development 1.115238e-4
GO:0006527 arginine catabolic process 1.127801e-4
GO:0048305 immunoglobulin secretion 1.138495e-4
GO:0006811 ion transport 1.153086e-4
GO:0090023 positive regulation of neutrophil chemotaxis 1.154682e-4
GO:0042990 regulation of transcription factor import into nucleus 1.173560e-4
GO:0022607 cellular component assembly 1.186639e-4
GO:0019220 regulation of phosphate metabolic process 1.194521e-4
GO:0042554 superoxide anion generation 1.198087e-4
GO:0032677 regulation of interleukin-8 production 1.198665e-4
GO:0007040 lysosome organization 1.206007e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0009611 response to wounding 2.196142e-17
GO:0050896 response to stimulus 9.366431e-16
GO:0050865 regulation of cell activation 2.501208e-14
GO:0042060 wound healing 2.696133e-14
GO:0002694 regulation of leukocyte activation 7.498869e-14
GO:0006950 response to stress 2.699272e-12
GO:0006812 cation transport 3.464030e-12
GO:0051249 regulation of lymphocyte activation 2.105131e-11
GO:0006810 transport 4.659632e-11
GO:0051234 establishment of localization 5.035210e-11
GO:0032879 regulation of localization 1.150474e-10
GO:0055114 oxidation-reduction process 1.172957e-10
GO:0006811 ion transport 2.487561e-10
GO:0010038 response to metal ion 2.666420e-10
GO:0051179 localization 6.746629e-10
GO:0050864 regulation of B cell activation 1.118430e-9
GO:0006952 defense response 2.528732e-9
GO:0002682 regulation of immune system process 2.561381e-9
GO:0019752 carboxylic acid metabolic process 3.355479e-9
GO:0070663 regulation of leukocyte proliferation 5.322435e-9
GO:0050670 regulation of lymphocyte proliferation 5.954310e-9
GO:0022610 biological adhesion 5.984360e-9
GO:0030001 metal ion transport 7.576495e-9
GO:0042180 cellular ketone metabolic process 7.825023e-9
GO:0007186 G-protein coupled receptor protein signaling pathway 8.626207e-9
GO:0032944 regulation of mononuclear cell proliferation 8.825842e-9
GO:0006082 organic acid metabolic process 9.670912e-9
GO:0010269 response to selenium ion 1.101737e-8
GO:0044281 small molecule metabolic process 1.249587e-8
GO:0006629 lipid metabolic process 1.258921e-8
GO:0006954 inflammatory response 1.277281e-8
GO:0007155 cell adhesion 1.348423e-8
GO:0030888 regulation of B cell proliferation 1.697683e-8
GO:0051250 negative regulation of lymphocyte activation 2.439963e-8
GO:0051716 cellular response to stimulus 3.204572e-8
GO:0048583 regulation of response to stimulus 3.755783e-8
GO:0071219 cellular response to molecule of bacterial origin 3.771987e-8
GO:0050863 regulation of T cell activation 3.822033e-8
GO:0050866 negative regulation of cell activation 4.027636e-8
GO:0071222 cellular response to lipopolysaccharide 5.268886e-8
GO:0008610 lipid biosynthetic process 5.877433e-8
GO:0043949 regulation of cAMP-mediated signaling 6.181847e-8
GO:0002695 negative regulation of leukocyte activation 7.480688e-8
GO:0042221 response to chemical stimulus 7.573355e-8
GO:0002376 immune system process 7.691285e-8
GO:0010715 regulation of extracellular matrix disassembly 8.897203e-8
GO:0051049 regulation of transport 1.077384e-7
GO:0044255 cellular lipid metabolic process 1.226169e-7
GO:0006749 glutathione metabolic process 1.269558e-7
GO:0055085 transmembrane transport 1.285837e-7
GO:0018879 biphenyl metabolic process 1.822613e-7
GO:0044062 regulation of excretion 2.269163e-7
GO:0010035 response to inorganic substance 2.436985e-7
GO:0006518 peptide metabolic process 3.045198e-7
GO:0019285 glycine betaine biosynthetic process from choline 3.218360e-7
GO:0002252 immune effector process 3.271168e-7
GO:0009098 leucine biosynthetic process 4.045631e-7
GO:0006550 isoleucine catabolic process 4.045631e-7
GO:0006578 betaine biosynthetic process 4.615884e-7
GO:0030890 positive regulation of B cell proliferation 4.682654e-7
GO:0051707 response to other organism 4.712652e-7
GO:0001818 negative regulation of cytokine production 4.718560e-7
GO:0007596 blood coagulation 4.724615e-7
GO:0002238 response to molecule of fungal origin 5.676143e-7
GO:0007599 hemostasis 5.890056e-7
GO:2000021 regulation of ion homeostasis 6.100872e-7
GO:0007166 cell surface receptor linked signaling pathway 9.498253e-7
GO:0065008 regulation of biological quality 1.011724e-6
GO:0050868 negative regulation of T cell activation 1.114473e-6
GO:0044283 small molecule biosynthetic process 1.305330e-6
GO:0050776 regulation of immune response 1.356534e-6
GO:0050871 positive regulation of B cell activation 1.392426e-6
GO:0009115 xanthine catabolic process 1.616026e-6
GO:0002683 negative regulation of immune system process 1.692274e-6
GO:0034765 regulation of ion transmembrane transport 1.725600e-6
GO:0051241 negative regulation of multicellular organismal process 1.815601e-6
GO:0045348 positive regulation of MHC class II biosynthetic process 2.114516e-6
GO:0002684 positive regulation of immune system process 2.134306e-6
GO:0071216 cellular response to biotic stimulus 2.602692e-6
GO:0060055 angiogenesis involved in wound healing 2.615568e-6
GO:0002819 regulation of adaptive immune response 2.819943e-6
GO:0009607 response to biotic stimulus 3.184075e-6
GO:0002637 regulation of immunoglobulin production 3.344168e-6
GO:0042246 tissue regeneration 3.602379e-6
GO:0051704 multi-organism process 3.962251e-6
GO:0051045 negative regulation of membrane protein ectodomain proteolysis 4.206083e-6
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 4.795698e-6
GO:0006968 cellular defense response 4.938574e-6
GO:0042100 B cell proliferation 5.139402e-6
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5.236270e-6
GO:0018963 phthalate metabolic process 5.403482e-6
GO:0090280 positive regulation of calcium ion import 5.654077e-6
GO:0032733 positive regulation of interleukin-10 production 5.864366e-6
GO:0051023 regulation of immunoglobulin secretion 5.968041e-6
GO:0002820 negative regulation of adaptive immune response 6.110252e-6
GO:0023052 signaling 6.218861e-6
GO:0043951 negative regulation of cAMP-mediated signaling 6.244855e-6
GO:0006694 steroid biosynthetic process 6.260998e-6
GO:0019376 galactolipid catabolic process 7.492377e-6
GO:0006702 androgen biosynthetic process 7.952643e-6
GO:0060249 anatomical structure homeostasis 1.034616e-5
GO:0002921 negative regulation of humoral immune response 1.083723e-5
GO:0070664 negative regulation of leukocyte proliferation 1.122505e-5
GO:0051046 regulation of secretion 1.131399e-5
GO:0002700 regulation of production of molecular mediator of immune response 1.201653e-5
GO:0050672 negative regulation of lymphocyte proliferation 1.324779e-5
GO:0061088 regulation of sequestering of zinc ion 1.363315e-5
GO:0035444 nickel ion transmembrane transport 1.363315e-5
GO:0019932 second-messenger-mediated signaling 1.412097e-5
GO:0051918 negative regulation of fibrinolysis 1.426440e-5
GO:0008284 positive regulation of cell proliferation 1.429037e-5
GO:0042953 lipoprotein transport 1.499178e-5
GO:0010312 detoxification of zinc ion 1.499951e-5
GO:0048304 positive regulation of isotype switching to IgG isotypes 1.543820e-5
GO:2000353 positive regulation of endothelial cell apoptosis 1.550465e-5
GO:0023051 regulation of signaling 1.604734e-5
GO:0048584 positive regulation of response to stimulus 1.751203e-5
GO:0002697 regulation of immune effector process 1.774635e-5
GO:0006551 leucine metabolic process 1.832230e-5
GO:0060206 estrous cycle phase 1.835708e-5
GO:0009620 response to fungus 1.866179e-5
GO:0007165 signal transduction 1.872596e-5
GO:0002443 leukocyte mediated immunity 2.074133e-5
GO:0034220 ion transmembrane transport 2.188463e-5
GO:0051054 positive regulation of DNA metabolic process 2.377176e-5
GO:0001817 regulation of cytokine production 2.387817e-5
GO:0045823 positive regulation of heart contraction 2.440622e-5
GO:0015920 lipopolysaccharide transport 2.809887e-5
GO:0018894 dibenzo-p-dioxin metabolic process 2.898258e-5
GO:0018026 peptidyl-lysine monomethylation 2.898258e-5
GO:0019374 galactolipid metabolic process 2.988619e-5
GO:0046113 nucleobase catabolic process 3.047615e-5
GO:0002889 regulation of immunoglobulin mediated immune response 3.190947e-5
GO:0006955 immune response 3.237994e-5
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 3.381842e-5
GO:0046485 ether lipid metabolic process 3.384811e-5
GO:0090066 regulation of anatomical structure size 3.437329e-5
GO:0006829 zinc ion transport 3.508152e-5
GO:0008202 steroid metabolic process 3.663737e-5
GO:0060658 nipple morphogenesis 3.845137e-5
GO:0035813 regulation of renal sodium excretion 3.893025e-5
GO:0050778 positive regulation of immune response 3.959364e-5
GO:0015734 taurine transport 4.027112e-5
GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine 4.027112e-5
GO:0055093 response to hyperoxia 4.168043e-5
GO:0009617 response to bacterium 4.313119e-5
GO:0048302 regulation of isotype switching to IgG isotypes 4.474539e-5
GO:0002449 lymphocyte mediated immunity 4.478371e-5
GO:0071732 cellular response to nitric oxide 4.586088e-5
GO:0002920 regulation of humoral immune response 4.906247e-5
GO:0032714 negative regulation of interleukin-5 production 5.071565e-5
GO:0048305 immunoglobulin secretion 5.071565e-5
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 5.159733e-5
GO:0048625 myoblast cell fate commitment 5.578206e-5
GO:0032653 regulation of interleukin-10 production 5.613934e-5
GO:0046110 xanthine metabolic process 5.810865e-5
GO:0030194 positive regulation of blood coagulation 6.008063e-5
GO:0032416 negative regulation of sodium:hydrogen antiporter activity 6.111042e-5
GO:0045911 positive regulation of DNA recombination 6.131037e-5
GO:0035814 negative regulation of renal sodium excretion 6.227035e-5
GO:0006575 cellular modified amino acid metabolic process 6.322569e-5
GO:0042127 regulation of cell proliferation 6.415421e-5
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 6.528428e-5
GO:0031340 positive regulation of vesicle fusion 6.529915e-5
GO:0007567 parturition 6.538063e-5
GO:0051856 adhesion to symbiont 6.585689e-5
GO:0009966 regulation of signal transduction 6.731648e-5
GO:0009308 amine metabolic process 6.807006e-5
GO:0015684 ferrous iron transport 6.914601e-5
GO:0006012 galactose metabolic process 7.067752e-5
GO:0090279 regulation of calcium ion import 7.410290e-5
GO:0046486 glycerolipid metabolic process 7.461613e-5
GO:0048870 cell motility 7.472165e-5
GO:0042448 progesterone metabolic process 7.934755e-5
GO:0010033 response to organic substance 7.994425e-5
GO:0007154 cell communication 8.670430e-5
GO:0010894 negative regulation of steroid biosynthetic process 8.762993e-5
GO:0002200 somatic diversification of immune receptors 9.278704e-5
GO:0014002 astrocyte development 9.390451e-5
GO:0071560 cellular response to transforming growth factor beta stimulus 9.740309e-5
GO:0032787 monocarboxylic acid metabolic process 9.748738e-5
GO:0016074 snoRNA metabolic process 9.864797e-5
GO:0071577 zinc ion transmembrane transport 9.914100e-5
GO:0015672 monovalent inorganic cation transport 1.017762e-4
GO:0045576 mast cell activation 1.018333e-4
GO:0002706 regulation of lymphocyte mediated immunity 1.020703e-4
GO:0035458 cellular response to interferon-beta 1.093115e-4
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 1.105613e-4
GO:0006688 glycosphingolipid biosynthetic process 1.133228e-4
GO:0035556 intracellular signal transduction 1.170369e-4
GO:0001775 cell activation 1.192821e-4
GO:0051917 regulation of fibrinolysis 1.221328e-4
GO:0032713 negative regulation of interleukin-4 production 1.221328e-4
GO:0070627 ferrous iron import 1.251527e-4
GO:0015692 lead ion transport 1.251527e-4
GO:0015676 vanadium ion transport 1.251527e-4
GO:0006520 cellular amino acid metabolic process 1.272428e-4
GO:0060575 intestinal epithelial cell differentiation 1.303294e-4
GO:0002237 response to molecule of bacterial origin 1.303599e-4
GO:0061303 cornea development in camera-type eye 1.326525e-4
GO:0045321 leukocyte activation 1.329503e-4
GO:0032101 regulation of response to external stimulus 1.341647e-4
GO:0002696 positive regulation of leukocyte activation 1.380971e-4
GO:0044092 negative regulation of molecular function 1.416837e-4
GO:0071423 malate transmembrane transport 1.459965e-4
GO:0015709 thiosulfate transport 1.459965e-4
GO:0034766 negative regulation of ion transmembrane transport 1.478933e-4
GO:0046640 regulation of alpha-beta T cell proliferation 1.548936e-4
GO:0070838 divalent metal ion transport 1.584450e-4
GO:2000741 positive regulation of mesenchymal stem cell differentiation 1.587435e-4
GO:0032696 negative regulation of interleukin-13 production 1.607348e-4
GO:0051043 regulation of membrane protein ectodomain proteolysis 1.670007e-4
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade 1.670007e-4
GO:0045346 regulation of MHC class II biosynthetic process 1.707906e-4
GO:0046394 carboxylic acid biosynthetic process 1.740436e-4
GO:0051240 positive regulation of multicellular organismal process 1.750642e-4
GO:0007229 integrin-mediated signaling pathway 1.764160e-4
GO:0072511 divalent inorganic cation transport 1.785254e-4
GO:0050867 positive regulation of cell activation 1.831414e-4
GO:0006833 water transport 1.839128e-4
GO:0009247 glycolipid biosynthetic process 1.933091e-4
GO:0002709 regulation of T cell mediated immunity 2.111912e-4
GO:0050928 negative regulation of positive chemotaxis 2.141855e-4
GO:0051256 spindle midzone assembly involved in mitosis 2.141855e-4
GO:0032782 bile acid secretion 2.141855e-4
GO:0006844 acyl carnitine transport 2.141855e-4
GO:0003096 renal sodium ion transport 2.141855e-4
GO:0010466 negative regulation of peptidase activity 2.239406e-4
GO:0010646 regulation of cell communication 2.286118e-4
GO:0048103 somatic stem cell division 2.309149e-4
GO:0042129 regulation of T cell proliferation 2.330829e-4
GO:0032496 response to lipopolysaccharide 2.337029e-4
GO:0009408 response to heat 2.399223e-4
GO:0042044 fluid transport 2.430757e-4
GO:0010716 negative regulation of extracellular matrix disassembly 2.497327e-4
GO:0007268 synaptic transmission 2.522606e-4
GO:0071260 cellular response to mechanical stimulus 2.559887e-4
GO:0051024 positive regulation of immunoglobulin secretion 2.592020e-4
GO:0035330 regulation of hippo signaling cascade 2.610356e-4
GO:0045766 positive regulation of angiogenesis 2.743329e-4
GO:0002366 leukocyte activation involved in immune response 2.743329e-4
GO:0051607 defense response to virus 2.747674e-4
GO:0031572 G2/M transition DNA damage checkpoint 2.852118e-4
GO:0070665 positive regulation of leukocyte proliferation 2.883858e-4
GO:0034605 cellular response to heat 2.886283e-4
GO:0050671 positive regulation of lymphocyte proliferation 2.900399e-4
GO:0015722 canalicular bile acid transport 2.924392e-4
GO:0009187 cyclic nucleotide metabolic process 2.985141e-4
GO:0006836 neurotransmitter transport 3.005677e-4
GO:0048710 regulation of astrocyte differentiation 3.106131e-4
GO:0033574 response to testosterone stimulus 3.249992e-4
GO:0042267 natural killer cell mediated cytotoxicity 3.274604e-4
GO:0043687 post-translational protein modification 3.274604e-4
GO:0046651 lymphocyte proliferation 3.348662e-4
GO:0051592 response to calcium ion 3.381911e-4
GO:0031576 G2/M transition checkpoint 3.521088e-4
GO:0043269 regulation of ion transport 3.547622e-4
GO:0035610 protein side chain deglutamylation 3.551944e-4
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 3.551944e-4
GO:0035609 C-terminal protein deglutamylation 3.551944e-4
GO:0020028 hemoglobin import 3.551944e-4
GO:0045445 myoblast differentiation 3.658475e-4
GO:0050878 regulation of body fluid levels 3.737229e-4
GO:0032074 negative regulation of nuclease activity 3.795043e-4
GO:0006435 threonyl-tRNA aminoacylation 3.795043e-4
GO:0019226 transmission of nerve impulse 3.795394e-4
GO:0032946 positive regulation of mononuclear cell proliferation 3.832234e-4
GO:0071421 manganese ion transmembrane transport 3.885772e-4
GO:0006145 purine base catabolic process 3.885772e-4
GO:0045073 regulation of chemokine biosynthetic process 3.901297e-4
GO:0032844 regulation of homeostatic process 4.023739e-4
GO:0045765 regulation of angiogenesis 4.034711e-4
GO:0040017 positive regulation of locomotion 4.039703e-4
GO:0042167 heme catabolic process 4.048686e-4
GO:0008203 cholesterol metabolic process 4.061939e-4
GO:0002520 immune system development 4.148470e-4
GO:0045830 positive regulation of isotype switching 4.189629e-4
GO:0010648 negative regulation of cell communication 4.210285e-4
GO:0032656 regulation of interleukin-13 production 4.315423e-4
GO:0071559 response to transforming growth factor beta stimulus 4.316121e-4
GO:0034599 cellular response to oxidative stress 4.339405e-4
GO:0022408 negative regulation of cell-cell adhesion 4.417937e-4
GO:0022407 regulation of cell-cell adhesion 4.435305e-4
GO:0050678 regulation of epithelial cell proliferation 4.492560e-4
GO:0046903 secretion 4.580930e-4
GO:0050855 regulation of B cell receptor signaling pathway 4.601729e-4
GO:0042159 lipoprotein catabolic process 4.601729e-4
GO:0042744 hydrogen peroxide catabolic process 4.647034e-4
GO:0051272 positive regulation of cellular component movement 4.680078e-4
GO:0045191 regulation of isotype switching 4.686892e-4
GO:0051712 positive regulation of killing of cells of other organism 4.759786e-4
GO:0035644 phosphoanandamide dephosphorylation 4.759786e-4
GO:0043392 negative regulation of DNA binding 4.791156e-4
GO:0030335 positive regulation of cell migration 4.877044e-4
GO:2000739 regulation of mesenchymal stem cell differentiation 4.958627e-4
GO:0014070 response to organic cyclic compound 4.970539e-4
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 5.019900e-4
GO:0046185 aldehyde catabolic process 5.019900e-4
GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 5.070021e-4
GO:0046641 positive regulation of alpha-beta T cell proliferation 5.137294e-4
GO:0015893 drug transport 5.138023e-4
GO:0050869 negative regulation of B cell activation 5.143918e-4
GO:0005513 detection of calcium ion 5.250041e-4
GO:0014823 response to activity 5.266366e-4
GO:0042743 hydrogen peroxide metabolic process 5.294174e-4
GO:0006695 cholesterol biosynthetic process 5.328595e-4
GO:0071702 organic substance transport 5.354270e-4
GO:0030879 mammary gland development 5.376954e-4
GO:0034767 positive regulation of ion transmembrane transport 5.422904e-4
GO:0007549 dosage compensation 5.427927e-4
GO:0050880 regulation of blood vessel size 5.446349e-4
GO:0009593 detection of chemical stimulus 5.456715e-4
GO:0046578 regulation of Ras protein signal transduction 5.469405e-4
GO:0033490 cholesterol biosynthetic process via lathosterol 5.719891e-4
GO:0050851 antigen receptor-mediated signaling pathway 5.804169e-4
GO:0002703 regulation of leukocyte mediated immunity 5.812392e-4
GO:0032490 detection of molecule of bacterial origin 5.826634e-4
GO:0043303 mast cell degranulation 5.888695e-4
GO:0035150 regulation of tube size 5.895279e-4
GO:0023057 negative regulation of signaling 5.950276e-4
GO:0044264 cellular polysaccharide metabolic process 5.997339e-4
GO:0032703 negative regulation of interleukin-2 production 6.021129e-4
GO:0048016 inositol phosphate-mediated signaling 6.047312e-4
GO:0032673 regulation of interleukin-4 production 6.102606e-4
GO:0010460 positive regulation of heart rate 6.150143e-4
GO:0043558 regulation of translational initiation in response to stress 6.153676e-4
GO:0002072 optic cup morphogenesis involved in camera-type eye development 6.181468e-4
GO:0006957 complement activation, alternative pathway 6.189527e-4
GO:0030814 regulation of cAMP metabolic process 6.254832e-4
GO:0051056 regulation of small GTPase mediated signal transduction 6.259318e-4
GO:0016064 immunoglobulin mediated immune response 6.577529e-4
GO:0070301 cellular response to hydrogen peroxide 6.637201e-4
GO:0002253 activation of immune response 6.650822e-4
GO:0045821 positive regulation of glycolysis 6.684967e-4
GO:0072282 metanephric nephron tubule morphogenesis 6.719303e-4
GO:0009612 response to mechanical stimulus 6.733558e-4
GO:0071731 response to nitric oxide 6.757451e-4
GO:0031099 regeneration 6.865523e-4
GO:0042063 gliogenesis 6.873523e-4
GO:0044106 cellular amine metabolic process 6.882689e-4
GO:0032908 regulation of transforming growth factor beta1 production 6.903400e-4
GO:2001020 regulation of response to DNA damage stimulus 7.018118e-4
GO:0016477 cell migration 7.038611e-4
GO:0001916 positive regulation of T cell mediated cytotoxicity 7.053276e-4
GO:0051098 regulation of binding 7.318306e-4
GO:0002275 myeloid cell activation involved in immune response 7.364620e-4
GO:0001909 leukocyte mediated cytotoxicity 7.407936e-4
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 7.475024e-4
GO:0019240 citrulline biosynthetic process 7.475024e-4
GO:0017121 phospholipid scrambling 7.475024e-4
GO:0019724 B cell mediated immunity 7.649387e-4
GO:0048712 negative regulation of astrocyte differentiation 7.772652e-4
GO:0009749 response to glucose stimulus 7.871147e-4
GO:0070574 cadmium ion transmembrane transport 7.895106e-4
GO:0002707 negative regulation of lymphocyte mediated immunity 7.905941e-4
GO:0043403 skeletal muscle tissue regeneration 7.917703e-4
GO:0042130 negative regulation of T cell proliferation 7.994149e-4
GO:0002377 immunoglobulin production 8.012712e-4
GO:0030817 regulation of cAMP biosynthetic process 8.031743e-4
GO:0019585 glucuronate metabolic process 8.034236e-4
GO:0010885 regulation of cholesterol storage 8.059862e-4
GO:0006233 dTDP biosynthetic process 8.117175e-4
GO:0051251 positive regulation of lymphocyte activation 8.194137e-4
GO:0033085 negative regulation of T cell differentiation in thymus 8.286784e-4
GO:0001894 tissue homeostasis 8.370619e-4
GO:0009410 response to xenobiotic stimulus 8.405057e-4
GO:2000377 regulation of reactive oxygen species metabolic process 8.504575e-4
GO:2000147 positive regulation of cell motility 8.534643e-4
GO:0072593 reactive oxygen species metabolic process 8.537371e-4
GO:2000736 regulation of stem cell differentiation 8.610963e-4
GO:0006406 mRNA export from nucleus 8.752110e-4
GO:0032098 regulation of appetite 8.831128e-4
GO:0034284 response to monosaccharide stimulus 8.848041e-4
GO:0043471 regulation of cellular carbohydrate catabolic process 8.872130e-4
GO:0043299 leukocyte degranulation 8.915721e-4
GO:0051239 regulation of multicellular organismal process 8.932434e-4
GO:0015855 pyrimidine base transport 8.944209e-4
GO:0060157 urinary bladder development 9.020444e-4
GO:0032943 mononuclear cell proliferation 9.074030e-4
GO:0009636 response to toxin 9.174328e-4
GO:0000012 single strand break repair 9.234642e-4
GO:0050854 regulation of antigen receptor-mediated signaling pathway 9.252291e-4
GO:0032461 positive regulation of protein oligomerization 9.532581e-4
GO:2000505 regulation of energy homeostasis 9.595744e-4
GO:0015697 quaternary ammonium group transport 9.611264e-4
GO:0002768 immune response-regulating cell surface receptor signaling pathway 9.667618e-4
GO:0006953 acute-phase response 9.678351e-4
GO:0042107 cytokine metabolic process 9.685018e-4
GO:0045087 innate immune response 9.724309e-4
GO:0034762 regulation of transmembrane transport 9.774838e-4
GO:0006405 RNA export from nucleus 9.904584e-4
GO:0045602 negative regulation of endothelial cell differentiation 1.009128e-3
GO:0065007 biological regulation 1.017248e-3
GO:0050852 T cell receptor signaling pathway 1.021836e-3
GO:0044262 cellular carbohydrate metabolic process 1.057812e-3
GO:0014074 response to purine-containing compound 1.063925e-3
GO:0051615 histamine uptake 1.076904e-3
GO:0043950 positive regulation of cAMP-mediated signaling 1.076904e-3
GO:0006633 fatty acid biosynthetic process 1.078656e-3
GO:0060586 multicellular organismal iron ion homeostasis 1.092470e-3
GO:0021589 cerebellum structural organization 1.092470e-3
GO:0050820 positive regulation of coagulation 1.102227e-3
GO:0046483 heterocycle metabolic process 1.117542e-3
GO:0090045 positive regulation of deacetylase activity 1.118562e-3
GO:0006577 betaine metabolic process 1.136850e-3
GO:0007521 muscle cell fate determination 1.161348e-3
GO:0035455 response to interferon-alpha 1.162894e-3
GO:0045777 positive regulation of blood pressure 1.182973e-3
GO:0010248 establishment or maintenance of transmembrane electrochemical gradient 1.188393e-3
GO:0010001 glial cell differentiation 1.194540e-3
GO:0051967 negative regulation of synaptic transmission, glutamatergic 1.201105e-3
GO:0051101 regulation of DNA binding 1.217812e-3
GO:0051593 response to folic acid 1.258929e-3
GO:0002711 positive regulation of T cell mediated immunity 1.259963e-3
GO:0002250 adaptive immune response 1.265726e-3
GO:0071345 cellular response to cytokine stimulus 1.272760e-3
GO:0008653 lipopolysaccharide metabolic process 1.274944e-3
GO:0009746 response to hexose stimulus 1.308228e-3
GO:0030799 regulation of cyclic nucleotide metabolic process 1.326893e-3
GO:0051099 positive regulation of binding 1.361629e-3
GO:0005975 carbohydrate metabolic process 1.446780e-3
GO:0030097 hemopoiesis 1.449340e-3
GO:0030802 regulation of cyclic nucleotide biosynthetic process 1.451245e-3
GO:0045079 negative regulation of chemokine biosynthetic process 1.473515e-3
GO:0031343 positive regulation of cell killing 1.475256e-3
GO:0033003 regulation of mast cell activation 1.486078e-3
GO:0003013 circulatory system process 1.490008e-3
GO:0046548 retinal rod cell development 1.492646e-3
GO:0050872 white fat cell differentiation 1.505984e-3
GO:0006104 succinyl-CoA metabolic process 1.535554e-3
GO:0060265 positive regulation of respiratory burst involved in inflammatory response 1.535554e-3
GO:0002232 leukocyte chemotaxis involved in inflammatory response 1.535554e-3
GO:0001781 neutrophil apoptosis 1.535554e-3
GO:0015837 amine transport 1.541840e-3
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1.550073e-3
GO:0050920 regulation of chemotaxis 1.570407e-3
GO:0019233 sensory perception of pain 1.574227e-3
GO:0032940 secretion by cell 1.585161e-3
GO:0009306 protein secretion 1.588129e-3
GO:0050900 leukocyte migration 1.590555e-3
GO:0019933 cAMP-mediated signaling 1.590941e-3
GO:0000018 regulation of DNA recombination 1.595383e-3
GO:0006813 potassium ion transport 1.597058e-3
GO:0034113 heterotypic cell-cell adhesion 1.615080e-3
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.616254e-3
GO:0006658 phosphatidylserine metabolic process 1.617258e-3
GO:0008228 opsonization 1.626369e-3
GO:0035037 sperm entry 1.666315e-3
GO:0042118 endothelial cell activation 1.670430e-3
GO:0032224 positive regulation of synaptic transmission, cholinergic 1.709032e-3
GO:0050790 regulation of catalytic activity 1.717959e-3
GO:0021782 glial cell development 1.774443e-3
GO:0030801 positive regulation of cyclic nucleotide metabolic process 1.779209e-3
GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.784438e-3
GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.784438e-3
GO:0031000 response to caffeine 1.790089e-3
GO:0090184 positive regulation of kidney development 1.791476e-3
GO:0006790 sulfur compound metabolic process 1.853345e-3
GO:0008285 negative regulation of cell proliferation 1.854332e-3
GO:0002903 negative regulation of B cell apoptosis 1.859583e-3
GO:0010975 regulation of neuron projection development 1.863969e-3
GO:0065009 regulation of molecular function 1.870262e-3
GO:0021536 diencephalon development 1.885305e-3
GO:0006573 valine metabolic process 1.888501e-3
GO:0032674 regulation of interleukin-5 production 1.889148e-3
GO:0032459 regulation of protein oligomerization 1.889148e-3
GO:0009231 riboflavin biosynthetic process 1.898280e-3
GO:0009743 response to carbohydrate stimulus 1.936925e-3
GO:0006928 cellular component movement 1.938755e-3
GO:0014075 response to amine stimulus 1.958312e-3
GO:0010886 positive regulation of cholesterol storage 1.964007e-3
GO:0006855 drug transmembrane transport 1.970196e-3
GO:0045822 negative regulation of heart contraction 1.972747e-3
GO:0002429 immune response-activating cell surface receptor signaling pathway 1.979476e-3
GO:0055069 zinc ion homeostasis 1.983243e-3
GO:0001782 B cell homeostasis 1.985985e-3
GO:0018410 C-terminal protein amino acid modification 2.004603e-3
GO:0071805 potassium ion transmembrane transport 2.027510e-3
GO:0042446 hormone biosynthetic process 2.044600e-3
GO:0043480 pigment accumulation in tissues 2.058523e-3
GO:0009101 glycoprotein biosynthetic process 2.084913e-3
GO:0033151 V(D)J recombination 2.090886e-3
GO:0001914 regulation of T cell mediated cytotoxicity 2.107188e-3
GO:0060900 embryonic camera-type eye formation 2.108265e-3
GO:0090193 positive regulation of glomerulus development 2.112155e-3
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2.112155e-3
GO:0070661 leukocyte proliferation 2.129344e-3
GO:0043068 positive regulation of programmed cell death 2.134227e-3
GO:0007159 leukocyte cell-cell adhesion 2.140344e-3
GO:0034614 cellular response to reactive oxygen species 2.141880e-3
GO:0046327 glycerol biosynthetic process from pyruvate 2.156451e-3
GO:0019543 propionate catabolic process 2.156451e-3
GO:0000041 transition metal ion transport 2.166438e-3
GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure 2.179368e-3
GO:0006650 glycerophospholipid metabolic process 2.201293e-3
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing 2.214493e-3
GO:0090285 negative regulation of protein glycosylation in Golgi 2.227150e-3
GO:0019452 L-cysteine catabolic process to taurine 2.227150e-3
GO:0010942 positive regulation of cell death 2.261426e-3
GO:0050708 regulation of protein secretion 2.304451e-3