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Novel motif:151

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name:motif151_GCCYGTGCMKCW

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0043088 regulation of Cdc42 GTPase activity 7.356144e-12
GO:0031442 positive regulation of mRNA 3'-end processing 5.502993e-10
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 7.018822e-10
GO:0060253 negative regulation of glial cell proliferation 9.012985e-10
GO:0060251 regulation of glial cell proliferation 9.650074e-10
GO:0043089 positive regulation of Cdc42 GTPase activity 3.054852e-9
GO:0002679 respiratory burst involved in defense response 3.751187e-9
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 7.354210e-9
GO:0045415 negative regulation of interleukin-8 biosynthetic process 1.420285e-8
GO:0043966 histone H3 acetylation 2.115038e-8
GO:0014014 negative regulation of gliogenesis 2.762719e-8
GO:0043585 nose morphogenesis 3.567033e-8
GO:0043487 regulation of RNA stability 4.519889e-8
GO:0019086 late viral mRNA transcription 7.210344e-8
GO:0010310 regulation of hydrogen peroxide metabolic process 7.465911e-8
GO:0043488 regulation of mRNA stability 7.563426e-8
GO:0071732 cellular response to nitric oxide 9.759904e-8
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 1.042450e-7
GO:0035357 peroxisome proliferator activated receptor signaling pathway 1.115152e-7
GO:0031064 negative regulation of histone deacetylation 1.531957e-7
GO:0071816 tail-anchored membrane protein insertion into ER membrane 2.056336e-7
GO:0022011 myelination in peripheral nervous system 2.561329e-7
GO:0050685 positive regulation of mRNA processing 2.671867e-7
GO:0035499 carnosine biosynthetic process 2.694063e-7
GO:0010626 negative regulation of Schwann cell proliferation 2.936217e-7
GO:0045217 cell-cell junction maintenance 3.836901e-7
GO:0014037 Schwann cell differentiation 3.892858e-7
GO:0045064 T-helper 2 cell differentiation 3.990234e-7
GO:0002315 marginal zone B cell differentiation 3.990234e-7
GO:0010739 positive regulation of protein kinase A signaling cascade 4.356311e-7
GO:0002149 hypochlorous acid biosynthetic process 4.588061e-7
GO:0007296 vitellogenesis 4.836617e-7
GO:0061099 negative regulation of protein tyrosine kinase activity 5.408044e-7
GO:2000272 negative regulation of receptor activity 6.112789e-7
GO:0006304 DNA modification 8.287977e-7
GO:0048561 establishment of organ orientation 8.320569e-7
GO:0014044 Schwann cell development 8.474091e-7
GO:0035507 regulation of myosin-light-chain-phosphatase activity 9.300668e-7
GO:0014807 regulation of somitogenesis 1.277190e-6
GO:0008078 mesodermal cell migration 1.297358e-6
GO:0045414 regulation of interleukin-8 biosynthetic process 1.307797e-6
GO:0071956 cellular component maintenance at cellular level 1.328805e-6
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 1.627417e-6
GO:0032864 activation of Cdc42 GTPase activity 1.877820e-6
GO:0044258 intestinal lipid catabolic process 1.879604e-6
GO:0018350 protein esterification 1.879604e-6
GO:0015891 siderophore transport 1.879604e-6
GO:0006801 superoxide metabolic process 1.920231e-6
GO:0018205 peptidyl-lysine modification 1.975322e-6
GO:0001885 endothelial cell development 2.223831e-6
GO:0035814 negative regulation of renal sodium excretion 2.226170e-6
GO:0006853 carnitine shuttle 2.340425e-6
GO:0071731 response to nitric oxide 2.467657e-6
GO:0000089 mitotic metaphase 3.024666e-6
GO:0001886 endothelial cell morphogenesis 3.103620e-6
GO:0003100 regulation of systemic arterial blood pressure by endothelin 3.126749e-6
GO:0032096 negative regulation of response to food 3.314011e-6
GO:0061014 positive regulation of mRNA catabolic process 3.503012e-6
GO:0043543 protein acylation 4.051996e-6
GO:0009264 deoxyribonucleotide catabolic process 4.604827e-6
GO:0010624 regulation of Schwann cell proliferation 4.902528e-6
GO:0000956 nuclear-transcribed mRNA catabolic process 4.957060e-6
GO:2000467 positive regulation of glycogen (starch) synthase activity 5.481819e-6
GO:0072337 modified amino acid transport 5.658447e-6
GO:0006285 base-excision repair, AP site formation 5.772856e-6
GO:0032099 negative regulation of appetite 6.821943e-6
GO:0021528 commissural neuron differentiation in spinal cord 6.890538e-6
GO:0050779 RNA destabilization 6.930013e-6
GO:0032926 negative regulation of activin receptor signaling pathway 7.127066e-6
GO:0033209 tumor necrosis factor-mediated signaling pathway 7.127934e-6
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion 9.165399e-6
GO:0006475 internal protein amino acid acetylation 9.350735e-6
GO:0042474 middle ear morphogenesis 9.489559e-6
GO:0097152 mesenchymal cell apoptosis 9.501187e-6
GO:2001037 positive regulation of tongue muscle cell differentiation 9.501187e-6
GO:0060982 coronary artery morphogenesis 9.501187e-6
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 1.018263e-5
GO:0032312 regulation of ARF GTPase activity 1.073130e-5
GO:0000093 mitotic telophase 1.181881e-5
GO:0007386 compartment pattern specification 1.253933e-5
GO:0061013 regulation of mRNA catabolic process 1.262394e-5
GO:2000974 negative regulation of pro-B cell differentiation 1.269193e-5
GO:0031284 positive regulation of guanylate cyclase activity 1.329796e-5
GO:0034214 protein hexamerization 1.368884e-5
GO:0045668 negative regulation of osteoblast differentiation 1.420962e-5
GO:0032383 regulation of intracellular cholesterol transport 1.475346e-5
GO:0097039 protein linear polyubiquitination 1.499739e-5
GO:0071472 cellular response to salt stress 1.520434e-5
GO:0033683 nucleotide-excision repair, DNA incision 1.656581e-5
GO:0007028 cytoplasm organization 1.676742e-5
GO:0009133 nucleoside diphosphate biosynthetic process 1.720619e-5
GO:0006707 cholesterol catabolic process 1.724492e-5
GO:0042274 ribosomal small subunit biogenesis 1.727243e-5
GO:0031848 protection from non-homologous end joining at telomere 1.792749e-5
GO:0045606 positive regulation of epidermal cell differentiation 1.897574e-5
GO:0015879 carnitine transport 1.928402e-5
GO:2000002 negative regulation of DNA damage checkpoint 2.030139e-5
GO:0070625 zymogen granule exocytosis 2.030139e-5
GO:0021551 central nervous system morphogenesis 2.030139e-5
GO:0021588 cerebellum formation 2.030139e-5
GO:0022004 midbrain-hindbrain boundary maturation during brain development 2.030139e-5
GO:0006473 protein acetylation 2.153716e-5
GO:0042093 T-helper cell differentiation 2.303564e-5
GO:0043313 regulation of neutrophil degranulation 2.353244e-5
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 2.433171e-5
GO:0043921 modulation by host of viral transcription 2.574664e-5
GO:0016188 synaptic vesicle maturation 2.728168e-5
GO:0031330 negative regulation of cellular catabolic process 2.794645e-5
GO:0030046 parallel actin filament bundle assembly 2.843280e-5
GO:0018393 internal peptidyl-lysine acetylation 2.850242e-5
GO:0033687 osteoblast proliferation 3.085997e-5
GO:0006449 regulation of translational termination 3.128017e-5
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration 3.240863e-5
GO:0010889 regulation of sequestering of triglyceride 3.252832e-5
GO:2000465 regulation of glycogen (starch) synthase activity 3.290319e-5
GO:0018394 peptidyl-lysine acetylation 3.482717e-5
GO:0007023 post-chaperonin tubulin folding pathway 3.504132e-5
GO:0042053 regulation of dopamine metabolic process 3.719477e-5
GO:0015887 pantothenate transmembrane transport 3.913218e-5
GO:0015878 biotin transport 3.913218e-5
GO:0032526 response to retinoic acid 4.015871e-5
GO:0046628 positive regulation of insulin receptor signaling pathway 4.654456e-5
GO:0016573 histone acetylation 4.654519e-5
GO:0034384 high-density lipoprotein particle clearance 4.706767e-5
GO:0021523 somatic motor neuron differentiation 4.706767e-5
GO:0060381 positive regulation of single-stranded telomeric DNA binding 4.739610e-5
GO:0042886 amide transport 5.445465e-5
GO:0030704 vitelline membrane formation 5.696067e-5
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 5.714836e-5
GO:0002115 store-operated calcium entry 5.717018e-5
GO:0009162 deoxyribonucleoside monophosphate metabolic process 5.721007e-5
GO:0071514 genetic imprinting 5.811651e-5
GO:0031440 regulation of mRNA 3'-end processing 6.011946e-5
GO:0045112 integrin biosynthetic process 6.037596e-5
GO:0001570 vasculogenesis 6.082472e-5
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 6.092614e-5
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 6.092614e-5
GO:0043353 enucleate erythrocyte differentiation 6.162942e-5
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 6.828398e-5
GO:0043314 negative regulation of neutrophil degranulation 7.337484e-5
GO:0051702 interaction with symbiont 7.631538e-5
GO:0015780 nucleotide-sugar transport 7.660177e-5
GO:0002268 follicular dendritic cell differentiation 8.134654e-5
GO:0032108 negative regulation of response to nutrient levels 8.653002e-5
GO:0051851 modification by host of symbiont morphology or physiology 9.519977e-5
GO:0006646 phosphatidylethanolamine biosynthetic process 9.746328e-5
GO:0051645 Golgi localization 9.796846e-5
GO:0042069 regulation of catecholamine metabolic process 9.945281e-5
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.017531e-4
GO:0033233 regulation of protein sumoylation 1.110897e-4
GO:0045686 negative regulation of glial cell differentiation 1.124386e-4
GO:0090141 positive regulation of mitochondrial fission 1.149735e-4
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 1.149735e-4
GO:2000077 negative regulation of type B pancreatic cell development 1.153233e-4
GO:0045007 depurination 1.153233e-4
GO:0032202 telomere assembly 1.185206e-4
GO:0032417 positive regulation of sodium:hydrogen antiporter activity 1.253529e-4
GO:0060711 labyrinthine layer development 1.331905e-4
GO:0043491 protein kinase B signaling cascade 1.365583e-4
GO:0034614 cellular response to reactive oxygen species 1.429714e-4
GO:0002536 respiratory burst involved in inflammatory response 1.432475e-4
GO:0006349 regulation of gene expression by genetic imprinting 1.443950e-4
GO:0060395 SMAD protein signal transduction 1.506626e-4
GO:0043923 positive regulation by host of viral transcription 1.542061e-4
GO:0045684 positive regulation of epidermis development 1.564851e-4
GO:0032012 regulation of ARF protein signal transduction 1.573360e-4
GO:0051668 localization within membrane 1.730188e-4
GO:0018022 peptidyl-lysine methylation 1.814794e-4
GO:0000305 response to oxygen radical 1.818337e-4
GO:0001892 embryonic placenta development 1.870558e-4
GO:0021986 habenula development 1.872074e-4
GO:0034389 lipid particle organization 1.950181e-4
GO:0051205 protein insertion into membrane 2.031538e-4
GO:0032226 positive regulation of synaptic transmission, dopaminergic 2.078052e-4
GO:0006402 mRNA catabolic process 2.134306e-4
GO:0060484 lung-associated mesenchyme development 2.162957e-4
GO:0043922 negative regulation by host of viral transcription 2.185382e-4
GO:0007006 mitochondrial membrane organization 2.255363e-4
GO:0070904 transepithelial L-ascorbic acid transport 2.303082e-4
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 2.328927e-4
GO:0070194 synaptonemal complex disassembly 2.328927e-4
GO:0044240 multicellular organismal lipid catabolic process 2.426480e-4
GO:0090342 regulation of cell aging 2.445626e-4
GO:0015969 guanosine tetraphosphate metabolic process 2.554155e-4
GO:0035803 egg coat formation 2.554155e-4
GO:0009438 methylglyoxal metabolic process 2.558982e-4
GO:0007020 microtubule nucleation 2.590828e-4
GO:0000387 spliceosomal snRNP assembly 2.595703e-4
GO:0046626 regulation of insulin receptor signaling pathway 2.627453e-4
GO:0046015 regulation of transcription by glucose 2.671325e-4
GO:0031669 cellular response to nutrient levels 2.780519e-4
GO:0018023 peptidyl-lysine trimethylation 2.835803e-4
GO:0022009 central nervous system vasculogenesis 2.905582e-4
GO:0032233 positive regulation of actin filament bundle assembly 2.906441e-4
GO:0034101 erythrocyte homeostasis 3.035873e-4
GO:0045082 positive regulation of interleukin-10 biosynthetic process 3.057730e-4
GO:0010452 histone H3-K36 methylation 3.057730e-4
GO:0009262 deoxyribonucleotide metabolic process 3.114667e-4
GO:0015781 pyrimidine nucleotide-sugar transport 3.140988e-4
GO:0046952 ketone body catabolic process 3.342933e-4
GO:0010871 negative regulation of receptor biosynthetic process 3.366009e-4
GO:0000072 M phase specific microtubule process 3.433801e-4
GO:0002886 regulation of myeloid leukocyte mediated immunity 3.434605e-4
GO:0070301 cellular response to hydrogen peroxide 3.442411e-4
GO:0019430 removal of superoxide radicals 3.623848e-4
GO:0016125 sterol metabolic process 3.726250e-4
GO:0015844 monoamine transport 3.784076e-4
GO:0032933 SREBP-mediated signaling pathway 3.965795e-4
GO:0031668 cellular response to extracellular stimulus 4.116042e-4
GO:0003374 dynamin polymerization involved in mitochondrial fission 4.154150e-4
GO:0090149 membrane fission involved in mitochondrial fission 4.154150e-4
GO:0072060 outer medullary collecting duct development 4.159470e-4
GO:0072061 inner medullary collecting duct development 4.159470e-4
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 4.159470e-4
GO:0071496 cellular response to external stimulus 4.347811e-4
GO:0019087 transformation of host cell by virus 4.409060e-4
GO:0030218 erythrocyte differentiation 4.475120e-4
GO:0045074 regulation of interleukin-10 biosynthetic process 4.504170e-4
GO:0001990 regulation of systemic arterial blood pressure by hormone 4.582227e-4
GO:0048549 positive regulation of pinocytosis 4.682318e-4
GO:0072595 maintenance of protein localization to organelle 4.766673e-4
GO:0097029 mature dendritic cell differentiation 4.910953e-4
GO:0071872 cellular response to epinephrine stimulus 4.910953e-4
GO:0008089 anterograde axon cargo transport 4.957669e-4
GO:0014013 regulation of gliogenesis 5.005450e-4
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 5.058819e-4
GO:0042747 circadian sleep/wake cycle, REM sleep 5.191778e-4
GO:0070875 positive regulation of glycogen metabolic process 5.201493e-4
GO:0045717 negative regulation of fatty acid biosynthetic process 5.257851e-4
GO:0006401 RNA catabolic process 5.306244e-4
GO:0048845 venous blood vessel morphogenesis 5.350469e-4
GO:0008589 regulation of smoothened signaling pathway 5.543760e-4
GO:0010713 negative regulation of collagen metabolic process 5.920372e-4
GO:0034589 hydroxyproline transport 6.053876e-4
GO:0015826 threonine transport 6.053876e-4
GO:0018027 peptidyl-lysine dimethylation 6.133603e-4
GO:0018208 peptidyl-proline modification 6.209433e-4
GO:0070873 regulation of glycogen metabolic process 6.247426e-4
GO:0001798 positive regulation of type IIa hypersensitivity 6.270835e-4
GO:0071470 cellular response to osmotic stress 6.371320e-4
GO:0009098 leucine biosynthetic process 6.416560e-4
GO:0043181 vacuolar sequestering 6.416560e-4
GO:0006550 isoleucine catabolic process 6.416560e-4
GO:0005985 sucrose metabolic process 6.416560e-4
GO:0000023 maltose metabolic process 6.416560e-4
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 6.503032e-4
GO:0060621 negative regulation of cholesterol import 6.578260e-4
GO:0015670 carbon dioxide transport 6.578260e-4
GO:0070602 regulation of centromeric sister chromatid cohesion 6.702329e-4
GO:0000413 protein peptidyl-prolyl isomerization 6.702704e-4
GO:0045618 positive regulation of keratinocyte differentiation 6.805349e-4
GO:0009265 2'-deoxyribonucleotide biosynthetic process 7.096145e-4
GO:0022411 cellular component disassembly 7.101533e-4
GO:0019083 viral transcription 7.300790e-4
GO:0071845 cellular component disassembly at cellular level 7.342963e-4
GO:0009650 UV protection 7.515716e-4
GO:0007063 regulation of sister chromatid cohesion 7.515716e-4
GO:0090031 positive regulation of steroid hormone biosynthetic process 7.569442e-4
GO:0061003 positive regulation of dendritic spine morphogenesis 7.627720e-4
GO:0032374 regulation of cholesterol transport 7.638236e-4
GO:0046902 regulation of mitochondrial membrane permeability 7.874511e-4
GO:0035088 establishment or maintenance of apical/basal cell polarity 8.164396e-4
GO:0043249 erythrocyte maturation 8.289353e-4
GO:0006386 termination of RNA polymerase III transcription 8.301793e-4
GO:0006385 transcription elongation from RNA polymerase III promoter 8.301793e-4
GO:0045218 zonula adherens maintenance 8.356242e-4
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 8.398193e-4
GO:0045879 negative regulation of smoothened signaling pathway 8.589224e-4
GO:0043163 cell envelope organization 8.903386e-4
GO:2000251 positive regulation of actin cytoskeleton reorganization 8.903386e-4
GO:0060620 regulation of cholesterol import 9.037540e-4
GO:0032365 intracellular lipid transport 9.122125e-4
GO:0009394 2'-deoxyribonucleotide metabolic process 9.134477e-4
GO:0006621 protein retention in ER lumen 9.378999e-4
GO:0010225 response to UV-C 9.378999e-4
GO:0071392 cellular response to estradiol stimulus 9.401722e-4
GO:0032205 negative regulation of telomere maintenance 9.436411e-4
GO:0035871 protein K11-linked deubiquitination 9.538002e-4
GO:0043418 homocysteine catabolic process 9.538002e-4
GO:0085018 maintenance of symbiont-containing vacuole via substance secreted by host 9.538002e-4
GO:0035378 carbon dioxide transmembrane transport 9.538002e-4
GO:0035377 transepithelial water transport 9.538002e-4
GO:0019343 cysteine biosynthetic process via cystathionine 9.538002e-4
GO:0019346 transsulfuration 9.538002e-4
GO:0030950 establishment or maintenance of actin cytoskeleton polarity 9.538002e-4
GO:0006535 cysteine biosynthetic process from serine 9.538002e-4
GO:0002089 lens morphogenesis in camera-type eye 9.613726e-4
GO:0034198 cellular response to amino acid starvation 9.819075e-4
GO:0008203 cholesterol metabolic process 9.839541e-4
GO:2001054 negative regulation of mesenchymal cell apoptosis 1.000481e-3
GO:0035269 protein O-linked mannosylation 1.000481e-3
GO:0006083 acetate metabolic process 1.000481e-3
GO:0006335 DNA replication-dependent nucleosome assembly 1.000481e-3
GO:0019242 methylglyoxal biosynthetic process 1.000481e-3
GO:0015669 gas transport 1.011206e-3
GO:0006457 protein folding 1.032007e-3
GO:0042363 fat-soluble vitamin catabolic process 1.034423e-3
GO:0042074 cell migration involved in gastrulation 1.043756e-3
GO:0030490 maturation of SSU-rRNA 1.047830e-3
GO:0050881 musculoskeletal movement 1.049147e-3
GO:0007635 chemosensory behavior 1.051218e-3
GO:0071705 nitrogen compound transport 1.058354e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 1.058902e-3
GO:0000303 response to superoxide 1.059215e-3
GO:0070483 detection of hypoxia 1.073350e-3
GO:2000209 regulation of anoikis 1.075937e-3
GO:0019448 L-cysteine catabolic process 1.088992e-3
GO:0006244 pyrimidine nucleotide catabolic process 1.089676e-3
GO:0048261 negative regulation of receptor-mediated endocytosis 1.092598e-3
GO:0015695 organic cation transport 1.093261e-3
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 1.107485e-3
GO:0018916 nitrobenzene metabolic process 1.107485e-3
GO:0070831 basement membrane assembly 1.107485e-3
GO:0046655 folic acid metabolic process 1.109021e-3
GO:0048710 regulation of astrocyte differentiation 1.129142e-3
GO:0060267 positive regulation of respiratory burst 1.140023e-3
GO:0060674 placenta blood vessel development 1.140358e-3
GO:0032897 negative regulation of viral transcription 1.168038e-3
GO:0060177 regulation of angiotensin metabolic process 1.178277e-3
GO:0035090 maintenance of apical/basal cell polarity 1.187099e-3
GO:0070345 negative regulation of fat cell proliferation 1.187099e-3
GO:0051323 metaphase 1.232213e-3
GO:0009223 pyrimidine deoxyribonucleotide catabolic process 1.233042e-3
GO:0032094 response to food 1.256618e-3
GO:0003148 outflow tract septum morphogenesis 1.270542e-3
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 1.297820e-3
GO:0060713 labyrinthine layer morphogenesis 1.301898e-3
GO:0048255 mRNA stabilization 1.307578e-3
GO:0010890 positive regulation of sequestering of triglyceride 1.346766e-3
GO:0072110 glomerular mesangial cell proliferation 1.380020e-3
GO:0060038 cardiac muscle cell proliferation 1.474370e-3
GO:0031365 N-terminal protein amino acid modification 1.482542e-3
GO:0090239 regulation of histone H4 acetylation 1.512655e-3
GO:0010216 maintenance of DNA methylation 1.512655e-3
GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis 1.529064e-3
GO:0044140 negative regulation of growth of symbiont on or near host surface 1.529574e-3
GO:0021512 spinal cord anterior/posterior patterning 1.529574e-3
GO:0015761 mannose transport 1.529574e-3
GO:0019413 acetate biosynthetic process 1.529574e-3
GO:0019542 propionate biosynthetic process 1.529574e-3
GO:0060708 spongiotrophoblast differentiation 1.582198e-3
GO:0007509 mesoderm migration involved in gastrulation 1.615641e-3
GO:0045109 intermediate filament organization 1.628820e-3
GO:0002335 mature B cell differentiation 1.645290e-3
GO:0030851 granulocyte differentiation 1.654327e-3
GO:2000300 regulation of synaptic vesicle exocytosis 1.662258e-3
GO:0009440 cyanate catabolic process 1.673698e-3
GO:0048378 regulation of lateral mesodermal cell fate specification 1.688211e-3
GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development 1.688211e-3
GO:0032423 regulation of mismatch repair 1.704301e-3
GO:0034227 tRNA thio-modification 1.714773e-3
GO:0002098 tRNA wobble uridine modification 1.714773e-3
GO:0032784 regulation of transcription elongation, DNA-dependent 1.719685e-3
GO:0045006 DNA deamination 1.748823e-3
GO:0042088 T-helper 1 type immune response 1.783401e-3
GO:0051965 positive regulation of synapse assembly 1.787345e-3
GO:0060669 embryonic placenta morphogenesis 1.815513e-3
GO:0006415 translational termination 1.827503e-3
GO:0009071 serine family amino acid catabolic process 1.847399e-3
GO:0060789 hair follicle placode formation 1.862034e-3
GO:0022027 interkinetic nuclear migration 1.862034e-3
GO:0031282 regulation of guanylate cyclase activity 1.889237e-3
GO:0000076 DNA replication checkpoint 1.920650e-3
GO:0019088 immortalization of host cell by virus 1.929124e-3
GO:0006231 dTMP biosynthetic process 1.929124e-3
GO:0008616 queuosine biosynthetic process 1.929124e-3
GO:0002002 regulation of angiotensin levels in blood 1.953283e-3
GO:0032329 serine transport 2.071513e-3
GO:0043467 regulation of generation of precursor metabolites and energy 2.085348e-3
GO:0006306 DNA methylation 2.086576e-3
GO:0060419 heart growth 2.132805e-3
GO:0042942 D-serine transport 2.136946e-3
GO:0043985 histone H4-R3 methylation 2.164961e-3
GO:0055017 cardiac muscle tissue growth 2.195518e-3
GO:0060977 coronary vasculature morphogenesis 2.217649e-3
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 2.217649e-3
GO:0018105 peptidyl-serine phosphorylation 2.231498e-3
GO:0015788 UDP-N-acetylglucosamine transport 2.238859e-3
GO:0032862 activation of Rho GTPase activity 2.239155e-3
GO:0072526 pyridine-containing compound catabolic process 2.260804e-3
GO:0048711 positive regulation of astrocyte differentiation 2.292896e-3
GO:0060052 neurofilament cytoskeleton organization 2.310839e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 2.311327e-3
GO:0019730 antimicrobial humoral response 2.335999e-3
GO:0006991 response to sterol depletion 2.338671e-3
GO:0040030 regulation of molecular function, epigenetic 2.362939e-3
GO:0010469 regulation of receptor activity 2.474439e-3
GO:0009189 deoxyribonucleoside diphosphate biosynthetic process 2.482340e-3
GO:0072109 glomerular mesangium development 2.482541e-3
GO:0071356 cellular response to tumor necrosis factor 2.532176e-3
GO:0048339 paraxial mesoderm development 2.550448e-3
GO:2000737 negative regulation of stem cell differentiation 2.557662e-3
GO:0060707 trophoblast giant cell differentiation 2.564525e-3
GO:0032765 positive regulation of mast cell cytokine production 2.640497e-3
GO:0060242 contact inhibition 2.640497e-3
GO:0021644 vagus nerve morphogenesis 2.640497e-3
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2.656101e-3
GO:0045725 positive regulation of glycogen biosynthetic process 2.715563e-3
GO:0090344 negative regulation of cell aging 2.728011e-3
GO:0005979 regulation of glycogen biosynthetic process 2.729495e-3
GO:0051567 histone H3-K9 methylation 2.752784e-3
GO:0090241 negative regulation of histone H4 acetylation 2.752784e-3
GO:0031953 negative regulation of protein autophosphorylation 2.784707e-3
GO:0001300 chronological cell aging 2.786673e-3
GO:0032682 negative regulation of chemokine production 2.815488e-3
GO:0097150 neuronal stem cell maintenance 2.852321e-3
GO:0043586 tongue development 2.854629e-3
GO:0035601 protein deacylation 2.871120e-3
GO:0033235 positive regulation of protein sumoylation 2.894219e-3
GO:0051414 response to cortisol stimulus 2.925184e-3
GO:0071476 cellular hypotonic response 2.948654e-3
GO:0046340 diacylglycerol catabolic process 2.948654e-3
GO:0032098 regulation of appetite 2.984485e-3
GO:0031670 cellular response to nutrient 3.035072e-3
GO:0016569 covalent chromatin modification 3.038706e-3
GO:0000244 assembly of spliceosomal tri-snRNP 3.049945e-3
GO:0006706 steroid catabolic process 3.069303e-3
GO:0034380 high-density lipoprotein particle assembly 3.094635e-3
GO:0090140 regulation of mitochondrial fission 3.134041e-3
GO:0070447 positive regulation of oligodendrocyte progenitor proliferation 3.138249e-3
GO:0045079 negative regulation of chemokine biosynthetic process 3.138249e-3
GO:0060216 definitive hemopoiesis 3.157033e-3
GO:0070327 thyroid hormone transport 3.170872e-3
GO:0042761 very long-chain fatty acid biosynthetic process 3.204954e-3
GO:0006476 protein deacetylation 3.226254e-3
GO:0006826 iron ion transport 3.250673e-3
GO:0045651 positive regulation of macrophage differentiation 3.252170e-3
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 3.290090e-3
GO:0010544 negative regulation of platelet activation 3.304868e-3
GO:0060716 labyrinthine layer blood vessel development 3.365205e-3
GO:0030423 targeting of mRNA for destruction involved in RNA interference 3.365251e-3
GO:2000651 positive regulation of sodium ion transmembrane transporter activity 3.503904e-3
GO:0051958 methotrexate transport 3.503904e-3
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 3.510910e-3
GO:0060872 semicircular canal development 3.517929e-3
GO:0021526 medial motor column neuron differentiation 3.521043e-3
GO:0002309 T cell proliferation involved in immune response 3.521043e-3
GO:0030823 regulation of cGMP metabolic process 3.536936e-3
GO:0010677 negative regulation of cellular carbohydrate metabolic process 3.584565e-3
GO:0010608 posttranscriptional regulation of gene expression 3.584641e-3
GO:0045806 negative regulation of endocytosis 3.650162e-3
GO:0030157 pancreatic juice secretion 3.652762e-3
GO:0071477 cellular hypotonic salinity response 3.652885e-3
GO:0060456 positive regulation of digestive system process 3.656974e-3
GO:0018026 peptidyl-lysine monomethylation 3.687083e-3
GO:0031017 exocrine pancreas development 3.716192e-3
GO:0016570 histone modification 3.736498e-3
GO:0042491 auditory receptor cell differentiation 3.772067e-3
GO:0015696 ammonium transport 3.777329e-3
GO:0032008 positive regulation of TOR signaling cascade 3.789078e-3
GO:0071879 positive regulation of adrenergic receptor signaling pathway 3.875767e-3
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 3.875767e-3
GO:0006742 NADP catabolic process 3.875767e-3
GO:0010905 negative regulation of UDP-glucose catabolic process 3.875767e-3
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway 3.939468e-3
GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 3.939468e-3
GO:0018293 protein-FAD linkage 3.939468e-3
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 3.939468e-3
GO:0033700 phospholipid efflux 3.948105e-3
GO:0072668 tubulin complex biogenesis 4.020388e-3
GO:0045008 depyrimidination 4.028046e-3
GO:0048712 negative regulation of astrocyte differentiation 4.088558e-3
GO:0021903 rostrocaudal neural tube patterning 4.107337e-3
GO:0010891 negative regulation of sequestering of triglyceride 4.112729e-3
GO:0045416 positive regulation of interleukin-8 biosynthetic process 4.116698e-3
GO:0032793 positive regulation of CREB transcription factor activity 4.134495e-3
GO:0043300 regulation of leukocyte degranulation 4.142130e-3
GO:0017187 peptidyl-glutamic acid carboxylation 4.192730e-3
GO:0090251 protein localization involved in establishment of planar polarity 4.213141e-3
GO:0060837 blood vessel endothelial cell differentiation 4.213141e-3
GO:0019402 galactitol metabolic process 4.213141e-3
GO:0060023 soft palate development 4.218544e-3
GO:0051457 maintenance of protein location in nucleus 4.248919e-3
GO:0009635 response to herbicide 4.313467e-3
GO:0002293 alpha-beta T cell differentiation involved in immune response 4.320282e-3
GO:0033146 regulation of estrogen receptor signaling pathway 4.333887e-3
GO:0033002 muscle cell proliferation 4.363811e-3
GO:0014898 cardiac muscle hypertrophy in response to stress 4.371381e-3
GO:0016575 histone deacetylation 4.433437e-3
GO:0072553 terminal button organization 4.434784e-3
GO:0060981 cell migration involved in coronary angiogenesis 4.434784e-3
GO:0071670 smooth muscle cell chemotaxis 4.434784e-3
GO:0002522 leukocyte migration involved in immune response 4.434784e-3
GO:0000088 mitotic prophase 4.434784e-3
GO:0035623 renal glucose absorption 4.434784e-3
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 4.442300e-3
GO:0072488 ammonium transmembrane transport 4.442300e-3
GO:0009153 purine deoxyribonucleotide biosynthetic process 4.442300e-3
GO:0051684 maintenance of Golgi location 4.506300e-3
GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway 4.506300e-3
GO:0090321 positive regulation of chylomicron remnant clearance 4.506300e-3
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production 4.506300e-3
GO:0010509 polyamine homeostasis 4.506300e-3
GO:0032738 positive regulation of interleukin-15 production 4.506300e-3
GO:0032853 positive regulation of Ran GTPase activity 4.506300e-3
GO:0003300 cardiac muscle hypertrophy 4.576314e-3
GO:0001302 replicative cell aging 4.655059e-3
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 4.693181e-3
GO:2000297 negative regulation of synapse maturation 4.693181e-3
GO:0050872 white fat cell differentiation 4.693429e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0010900 negative regulation of phosphatidylcholine catabolic process 2.661097e-9
GO:0034447 very-low-density lipoprotein particle clearance 2.290557e-7
GO:0031558 induction of apoptosis in response to chemical stimulus 2.635961e-7
GO:0048305 immunoglobulin secretion 4.529390e-7
GO:0031442 positive regulation of mRNA 3'-end processing 7.090050e-7
GO:0061028 establishment of endothelial barrier 2.109206e-6
GO:0014045 establishment of endothelial blood-brain barrier 2.911851e-6
GO:0050685 positive regulation of mRNA processing 5.710661e-6
GO:0051583 dopamine uptake 6.697780e-6
GO:0031440 regulation of mRNA 3'-end processing 7.296857e-6
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 9.729041e-6
GO:0045922 negative regulation of fatty acid metabolic process 1.138656e-5
GO:0033239 negative regulation of cellular amine metabolic process 1.618344e-5
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity 1.805479e-5
GO:0006654 phosphatidic acid biosynthetic process 2.126386e-5
GO:0019285 glycine betaine biosynthetic process from choline 3.421116e-5
GO:0048535 lymph node development 3.546939e-5
GO:0022009 central nervous system vasculogenesis 3.696797e-5
GO:0018193 peptidyl-amino acid modification 3.895113e-5
GO:2001037 positive regulation of tongue muscle cell differentiation 4.287873e-5
GO:0010424 DNA methylation on cytosine within a CG sequence 4.565470e-5
GO:0018230 peptidyl-L-cysteine S-palmitoylation 4.770877e-5
GO:0010155 regulation of proton transport 4.778101e-5
GO:0000578 embryonic axis specification 5.213550e-5
GO:0042398 cellular modified amino acid biosynthetic process 5.364625e-5
GO:0001885 endothelial cell development 6.612739e-5
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 6.615998e-5
GO:0018293 protein-FAD linkage 6.615998e-5
GO:0001579 medium-chain fatty acid transport 6.615998e-5
GO:0006611 protein export from nucleus 7.314656e-5
GO:0001777 T cell homeostatic proliferation 7.346620e-5
GO:0034214 protein hexamerization 7.567434e-5
GO:2000275 regulation of oxidative phosphorylation uncoupler activity 8.413085e-5
GO:0070286 axonemal dynein complex assembly 8.413085e-5
GO:0002407 dendritic cell chemotaxis 9.482101e-5
GO:0060896 neural plate pattern specification 9.868546e-5
GO:0090234 regulation of kinetochore assembly 9.998512e-5
GO:0090169 regulation of spindle assembly 9.998512e-5
GO:0031848 protection from non-homologous end joining at telomere 1.060981e-4
GO:0002352 B cell negative selection 1.097534e-4
GO:0061014 positive regulation of mRNA catabolic process 1.152837e-4
GO:0045717 negative regulation of fatty acid biosynthetic process 1.405832e-4
GO:0010891 negative regulation of sequestering of triglyceride 1.455860e-4
GO:0001963 synaptic transmission, dopaminergic 1.626053e-4
GO:0032776 DNA methylation on cytosine 1.668467e-4
GO:0070316 regulation of G0 to G1 transition 1.859995e-4
GO:0001570 vasculogenesis 2.066668e-4
GO:0051085 chaperone mediated protein folding requiring cofactor 2.080792e-4
GO:2000781 positive regulation of double-strand break repair 2.203187e-4
GO:0015966 diadenosine tetraphosphate biosynthetic process 2.203187e-4
GO:0072610 interleukin-12 secretion 2.488309e-4
GO:0097022 lymphocyte migration into lymph node 2.488309e-4
GO:0034441 plasma lipoprotein particle oxidation 2.488309e-4
GO:0002077 acrosome matrix dispersal 2.489881e-4
GO:0034393 positive regulation of smooth muscle cell apoptosis 2.544649e-4
GO:0034983 peptidyl-lysine deacetylation 2.638117e-4
GO:0071242 cellular response to ammonium ion 2.721281e-4
GO:0018105 peptidyl-serine phosphorylation 2.780428e-4
GO:0046849 bone remodeling 2.943084e-4
GO:0045920 negative regulation of exocytosis 3.231981e-4
GO:0032239 regulation of nucleobase-containing compound transport 3.526937e-4
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 3.526937e-4
GO:0001844 protein insertion into mitochondrial membrane involved in induction of apoptosis 3.526937e-4
GO:0070232 regulation of T cell apoptosis 3.569318e-4
GO:0051341 regulation of oxidoreductase activity 3.611115e-4
GO:0060696 regulation of phospholipid catabolic process 3.698126e-4
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 3.813766e-4
GO:0043301 negative regulation of leukocyte degranulation 4.047987e-4
GO:0051168 nuclear export 4.311635e-4
GO:0002268 follicular dendritic cell differentiation 4.553901e-4
GO:0051204 protein insertion into mitochondrial membrane 4.601453e-4
GO:0043587 tongue morphogenesis 4.682993e-4
GO:0006513 protein monoubiquitination 4.961587e-4
GO:0097026 dendritic cell dendrite assembly 5.164549e-4
GO:0043314 negative regulation of neutrophil degranulation 5.275704e-4
GO:0085020 protein K6-linked ubiquitination 5.412185e-4
GO:0018209 peptidyl-serine modification 5.792113e-4
GO:0033523 histone H2B ubiquitination 5.874906e-4
GO:0051865 protein autoubiquitination 5.885391e-4
GO:0045446 endothelial cell differentiation 5.956307e-4
GO:0021999 neural plate anterior/posterior regionalization 6.011333e-4
GO:0003158 endothelium development 6.022585e-4
GO:0035725 sodium ion transmembrane transport 6.311857e-4
GO:0002897 positive regulation of central B cell tolerance induction 6.579900e-4
GO:0002508 central tolerance induction 6.579900e-4
GO:0033590 response to cobalamin 6.628096e-4
GO:0002635 negative regulation of germinal center formation 6.628096e-4
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 6.706325e-4
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 6.788472e-4
GO:0097107 postsynaptic density assembly 6.788472e-4
GO:0045585 positive regulation of cytotoxic T cell differentiation 6.788472e-4
GO:0046604 positive regulation of mitotic centrosome separation 7.336667e-4
GO:0021528 commissural neuron differentiation in spinal cord 7.336667e-4
GO:0035234 germ cell programmed cell death 7.659839e-4
GO:0051084 'de novo' posttranslational protein folding 7.821171e-4
GO:0051135 positive regulation of NK T cell activation 7.845519e-4
GO:0006346 methylation-dependent chromatin silencing 7.851798e-4
GO:0090083 regulation of inclusion body assembly 7.851798e-4
GO:0070542 response to fatty acid 8.597188e-4
GO:0072061 inner medullary collecting duct development 8.614367e-4
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 8.614367e-4
GO:0072060 outer medullary collecting duct development 8.614367e-4
GO:0071870 cellular response to catecholamine stimulus 9.074814e-4
GO:0021533 cell differentiation in hindbrain 9.569133e-4
GO:0043951 negative regulation of cAMP-mediated signaling 9.950235e-4
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 9.950235e-4
GO:0016539 intein-mediated protein splicing 9.950235e-4
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 9.950235e-4
GO:0042149 cellular response to glucose starvation 1.029661e-3
GO:0006099 tricarboxylic acid cycle 1.035341e-3
GO:0016242 negative regulation of macroautophagy 1.089774e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 1.113296e-3
GO:0060897 neural plate regionalization 1.122141e-3
GO:0015851 nucleobase transport 1.122141e-3
GO:0009880 embryonic pattern specification 1.150335e-3
GO:0072074 kidney mesenchyme development 1.213369e-3
GO:0009199 ribonucleoside triphosphate metabolic process 1.221327e-3
GO:0030917 midbrain-hindbrain boundary development 1.227795e-3
GO:0009205 purine ribonucleoside triphosphate metabolic process 1.288842e-3
GO:0021587 cerebellum morphogenesis 1.293494e-3
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 1.299430e-3
GO:0006844 acyl carnitine transport 1.299430e-3
GO:0060299 negative regulation of sarcomere organization 1.299430e-3
GO:0046330 positive regulation of JNK cascade 1.357462e-3
GO:0033085 negative regulation of T cell differentiation in thymus 1.368707e-3
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 1.384502e-3
GO:0090026 positive regulation of monocyte chemotaxis 1.385576e-3
GO:0045345 positive regulation of MHC class I biosynthetic process 1.444173e-3
GO:0030950 establishment or maintenance of actin cytoskeleton polarity 1.444173e-3
GO:0015844 monoamine transport 1.453669e-3
GO:0006658 phosphatidylserine metabolic process 1.477623e-3
GO:0006808 regulation of nitrogen utilization 1.497267e-3
GO:0060674 placenta blood vessel development 1.514272e-3
GO:0044253 positive regulation of multicellular organismal metabolic process 1.559663e-3
GO:0043313 regulation of neutrophil degranulation 1.578860e-3
GO:0008589 regulation of smoothened signaling pathway 1.592005e-3
GO:0070368 positive regulation of hepatocyte differentiation 1.602608e-3
GO:0010661 positive regulation of muscle cell apoptosis 1.615782e-3
GO:0046847 filopodium assembly 1.641597e-3
GO:0045792 negative regulation of cell size 1.676583e-3
GO:0090045 positive regulation of deacetylase activity 1.680495e-3
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 1.680495e-3
GO:0046602 regulation of mitotic centrosome separation 1.705699e-3
GO:0019264 glycine biosynthetic process from serine 1.705699e-3
GO:0061077 chaperone-mediated protein folding 1.713848e-3
GO:0072205 metanephric collecting duct development 1.759186e-3
GO:0016241 regulation of macroautophagy 1.795059e-3
GO:0010833 telomere maintenance via telomere lengthening 1.795059e-3
GO:0009109 coenzyme catabolic process 1.808925e-3
GO:0043543 protein acylation 1.865292e-3
GO:0042347 negative regulation of NF-kappaB import into nucleus 1.882760e-3
GO:0051590 positive regulation of neurotransmitter transport 1.908949e-3
GO:0051573 negative regulation of histone H3-K9 methylation 1.954547e-3
GO:0050779 RNA destabilization 1.954547e-3
GO:0010887 negative regulation of cholesterol storage 1.985972e-3
GO:0033004 negative regulation of mast cell activation 2.049721e-3
GO:0032855 positive regulation of Rac GTPase activity 2.087642e-3
GO:0045880 positive regulation of smoothened signaling pathway 2.105972e-3
GO:0046341 CDP-diacylglycerol metabolic process 2.110232e-3
GO:0015684 ferrous iron transport 2.150545e-3
GO:0006405 RNA export from nucleus 2.207542e-3
GO:0050718 positive regulation of interleukin-1 beta secretion 2.293723e-3
GO:0018210 peptidyl-threonine modification 2.352101e-3
GO:0002649 regulation of tolerance induction to self antigen 2.405004e-3
GO:0048239 negative regulation of DNA recombination at telomere 2.443079e-3
GO:0046670 positive regulation of retinal cell programmed cell death 2.443079e-3
GO:0033617 mitochondrial respiratory chain complex IV assembly 2.443079e-3
GO:0002525 acute inflammatory response to non-antigenic stimulus 2.443079e-3
GO:0006430 lysyl-tRNA aminoacylation 2.443079e-3
GO:0030035 microspike assembly 2.577200e-3
GO:0072075 metanephric mesenchyme development 2.699919e-3
GO:0009146 purine nucleoside triphosphate catabolic process 2.751229e-3
GO:0009207 purine ribonucleoside triphosphate catabolic process 2.755317e-3
GO:0051580 regulation of neurotransmitter uptake 2.761184e-3
GO:0006406 mRNA export from nucleus 2.839837e-3
GO:0051984 positive regulation of chromosome segregation 2.850069e-3
GO:0006184 GTP catabolic process 2.921246e-3
GO:0009144 purine nucleoside triphosphate metabolic process 2.935318e-3
GO:0045879 negative regulation of smoothened signaling pathway 2.952860e-3
GO:0090399 replicative senescence 2.978266e-3
GO:0061205 paramesonephric duct development 2.981500e-3
GO:0045184 establishment of protein localization 3.074580e-3
GO:2000744 positive regulation of anterior head development 3.076814e-3
GO:0045905 positive regulation of translational termination 3.076814e-3
GO:0006452 translational frameshifting 3.076814e-3
GO:0045901 positive regulation of translational elongation 3.076814e-3
GO:0032933 SREBP-mediated signaling pathway 3.194845e-3
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 3.264894e-3
GO:0007144 female meiosis I 3.264894e-3
GO:0016575 histone deacetylation 3.278841e-3
GO:0002339 B cell selection 3.332321e-3
GO:0001977 renal system process involved in regulation of blood volume 3.358126e-3
GO:0051323 metaphase 3.385224e-3
GO:0070243 regulation of thymocyte apoptosis 3.522156e-3
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 3.600583e-3
GO:0045660 positive regulation of neutrophil differentiation 3.600583e-3
GO:0035507 regulation of myosin-light-chain-phosphatase activity 3.600583e-3
GO:0070318 positive regulation of G0 to G1 transition 3.671524e-3
GO:0009107 lipoate biosynthetic process 3.683791e-3
GO:0045210 FasL biosynthetic process 3.683791e-3
GO:0006526 arginine biosynthetic process 3.683791e-3
GO:0060385 axonogenesis involved in innervation 3.813755e-3
GO:0009143 nucleoside triphosphate catabolic process 3.862083e-3
GO:0035640 exploration behavior 3.925205e-3
GO:0006837 serotonin transport 3.953830e-3
GO:0014015 positive regulation of gliogenesis 4.032675e-3
GO:2000543 positive regulation of gastrulation 4.033346e-3
GO:0045175 basal protein localization 4.063044e-3
GO:2000412 positive regulation of thymocyte migration 4.152397e-3
GO:0002518 lymphocyte chemotaxis across high endothelial venule 4.152397e-3
GO:0006449 regulation of translational termination 4.152397e-3
GO:0015670 carbon dioxide transport 4.288765e-3
GO:2000779 regulation of double-strand break repair 4.305792e-3
GO:0032768 regulation of monooxygenase activity 4.318292e-3
GO:0015724 formate transport 4.319670e-3
GO:0015876 acetyl-CoA transport 4.319670e-3
GO:0061302 smooth muscle cell-matrix adhesion 4.322386e-3
GO:0000053 argininosuccinate metabolic process 4.322386e-3
GO:0072199 regulation of mesenchymal cell proliferation involved in ureter development 4.354763e-3
GO:0015780 nucleotide-sugar transport 4.354763e-3
GO:0046958 nonassociative learning 4.370851e-3
GO:0006668 sphinganine-1-phosphate metabolic process 4.370851e-3
GO:0043949 regulation of cAMP-mediated signaling 4.383420e-3
GO:0015872 dopamine transport 4.548746e-3
GO:0009141 nucleoside triphosphate metabolic process 4.572476e-3
GO:0010721 negative regulation of cell development 4.633522e-3
GO:0032094 response to food 4.677945e-3
GO:0048368 lateral mesoderm development 4.680827e-3
GO:0006863 purine base transport 4.680827e-3
GO:0001909 leukocyte mediated cytotoxicity 4.707662e-3
GO:0060026 convergent extension 4.826295e-3
GO:0006413 translational initiation 4.895267e-3
GO:0030835 negative regulation of actin filament depolymerization 4.971590e-3
GO:0043503 skeletal muscle fiber adaptation 4.975495e-3
GO:0051588 regulation of neurotransmitter transport 4.985242e-3
GO:0060458 right lung development 5.014516e-3
GO:0048597 post-embryonic camera-type eye morphogenesis 5.014516e-3
GO:0019348 dolichol metabolic process 5.014516e-3
GO:0002036 regulation of L-glutamate transport 5.014516e-3
GO:0045602 negative regulation of endothelial cell differentiation 5.014516e-3
GO:0051354 negative regulation of oxidoreductase activity 5.028848e-3
GO:0032967 positive regulation of collagen biosynthetic process 5.028848e-3
GO:0060439 trachea morphogenesis 5.057367e-3
GO:0010464 regulation of mesenchymal cell proliferation 5.132800e-3
GO:0046831 regulation of RNA export from nucleus 5.186436e-3
GO:0072488 ammonium transmembrane transport 5.208980e-3
GO:0018345 protein palmitoylation 5.251101e-3
GO:0051353 positive regulation of oxidoreductase activity 5.280607e-3
GO:0016567 protein ubiquitination 5.292740e-3
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 5.301335e-3
GO:0060837 blood vessel endothelial cell differentiation 5.338066e-3
GO:0032321 positive regulation of Rho GTPase activity 5.391006e-3
GO:0001840 neural plate development 5.393652e-3
GO:0050768 negative regulation of neurogenesis 5.403102e-3
GO:0010889 regulation of sequestering of triglyceride 5.475156e-3
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 5.540818e-3
GO:0006282 regulation of DNA repair 5.637680e-3
GO:0046590 embryonic leg morphogenesis 5.669607e-3
GO:0033158 regulation of protein import into nucleus, translocation 5.734087e-3
GO:0060058 positive regulation of apoptosis involved in mammary gland involution 5.845391e-3
GO:0051001 negative regulation of nitric-oxide synthase activity 5.845391e-3
GO:0007257 activation of JUN kinase activity 5.950168e-3
GO:0007354 zygotic determination of anterior/posterior axis, embryo 6.038717e-3
GO:0070932 histone H3 deacetylation 6.055104e-3
GO:0060060 post-embryonic retina morphogenesis in camera-type eye 6.055104e-3
GO:0035444 nickel ion transmembrane transport 6.055104e-3
GO:0032769 negative regulation of monooxygenase activity 6.060253e-3
GO:0090141 positive regulation of mitochondrial fission 6.126028e-3
GO:0033490 cholesterol biosynthetic process via lathosterol 6.126028e-3
GO:0001556 oocyte maturation 6.215469e-3
GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development 6.332357e-3
GO:0070474 positive regulation of uterine smooth muscle contraction 6.332357e-3
GO:0045217 cell-cell junction maintenance 6.423296e-3
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 6.440227e-3
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 6.440227e-3
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 6.440227e-3
GO:0018205 peptidyl-lysine modification 6.730757e-3
GO:0048793 pronephros development 6.772985e-3
GO:0060712 spongiotrophoblast layer development 6.772985e-3
GO:0009261 ribonucleotide catabolic process 6.775623e-3
GO:0070245 positive regulation of thymocyte apoptosis 6.780360e-3
GO:0006687 glycosphingolipid metabolic process 6.791768e-3
GO:0070234 positive regulation of T cell apoptosis 6.943412e-3
GO:0021575 hindbrain morphogenesis 6.978715e-3
GO:0032847 regulation of cellular pH reduction 6.993843e-3
GO:0010869 regulation of receptor biosynthetic process 7.037549e-3
GO:0043491 protein kinase B signaling cascade 7.092265e-3
GO:0015074 DNA integration 7.165297e-3
GO:0006577 betaine metabolic process 7.165297e-3
GO:0051030 snRNA transport 7.188121e-3
GO:0006998 nuclear envelope organization 7.228431e-3
GO:0046039 GTP metabolic process 7.274178e-3
GO:0021997 neural plate axis specification 7.309656e-3
GO:0016559 peroxisome fission 7.309656e-3
GO:0000089 mitotic metaphase 7.309656e-3
GO:0006551 leucine metabolic process 7.309656e-3
GO:0032849 positive regulation of cellular pH reduction 7.335210e-3
GO:0060716 labyrinthine layer blood vessel development 7.392849e-3
GO:0046356 acetyl-CoA catabolic process 7.557398e-3
GO:0072054 renal outer medulla development 7.705628e-3
GO:2000015 regulation of determination of dorsal identity 7.705628e-3
GO:0006705 mineralocorticoid biosynthetic process 7.705628e-3
GO:0006370 mRNA capping 7.705628e-3
GO:0044091 membrane biogenesis 7.705628e-3
GO:0006657 CDP-choline pathway 7.735944e-3
GO:0001768 establishment of T cell polarity 7.735944e-3
GO:0006663 platelet activating factor biosynthetic process 7.830529e-3
GO:2000426 negative regulation of apoptotic cell clearance 7.908119e-3
GO:0070585 protein localization in mitochondrion 7.990445e-3
GO:0005981 regulation of glycogen catabolic process 8.128393e-3
GO:0070317 negative regulation of G0 to G1 transition 8.135185e-3
GO:0080164 regulation of nitric oxide metabolic process 8.135185e-3
GO:0045234 protein palmitoleylation 8.135185e-3
GO:0035502 metanephric ureteric bud development 8.135185e-3
GO:0009443 pyridoxal 5'-phosphate salvage 8.135185e-3
GO:0034474 U2 snRNA 3'-end processing 8.135185e-3
GO:0006948 induction by virus of host cell-cell fusion 8.135185e-3
GO:0015031 protein transport 8.294855e-3
GO:0032241 positive regulation of nucleobase-containing compound transport 8.351632e-3
GO:0018364 peptidyl-glutamine methylation 8.351632e-3
GO:0016191 synaptic vesicle uncoating 8.351632e-3
GO:0044246 regulation of multicellular organismal metabolic process 8.497181e-3
GO:0033037 polysaccharide localization 8.517657e-3
GO:0021681 cerebellar granular layer development 8.556370e-3
GO:0021548 pons development 8.605189e-3
GO:0009306 protein secretion 8.610814e-3
GO:0033036 macromolecule localization 8.615438e-3
GO:0051586 positive regulation of dopamine uptake 8.819318e-3
GO:2000649 regulation of sodium ion transmembrane transporter activity 8.918100e-3
GO:0002663 positive regulation of B cell tolerance induction 8.918100e-3
GO:0021702 cerebellar Purkinje cell differentiation 8.918494e-3
GO:0048477 oogenesis 8.942713e-3
GO:0060534 trachea cartilage development 9.057797e-3
GO:0009154 purine ribonucleotide catabolic process 9.063432e-3
GO:0046605 regulation of centrosome cycle 9.236622e-3
GO:0060017 parathyroid gland development 9.319255e-3
GO:0051823 regulation of synapse structural plasticity 9.319255e-3
GO:0090224 regulation of spindle organization 9.321390e-3
GO:0051584 regulation of dopamine uptake 9.321390e-3
GO:0002053 positive regulation of mesenchymal cell proliferation 9.365837e-3
GO:0072203 cell proliferation involved in metanephros development 9.372694e-3
GO:0010524 positive regulation of calcium ion transport into cytosol 9.536013e-3
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 9.555759e-3
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 9.555759e-3
GO:0006713 glucocorticoid catabolic process 9.555759e-3
GO:0022417 protein maturation by protein folding 9.555759e-3
GO:0018192 enzyme active site formation via L-cysteine persulfide 9.555759e-3
GO:0032277 negative regulation of gonadotropin secretion 9.641936e-3
GO:0018094 protein polyglycylation 9.641936e-3
GO:0051187 cofactor catabolic process 1.007678e-2
GO:0032862 activation of Rho GTPase activity 1.040339e-2
GO:0030100 regulation of endocytosis 1.042617e-2
GO:0002432 granuloma formation 1.063047e-2
GO:0090140 regulation of mitochondrial fission 1.063047e-2
GO:0044332 Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.063047e-2
GO:0071502 cellular response to temperature stimulus 1.065948e-2
GO:0097152 mesenchymal cell apoptosis 1.065948e-2
GO:0042664 negative regulation of endodermal cell fate specification 1.065948e-2
GO:0071104 response to interleukin-9 1.065948e-2
GO:0002380 immunoglobulin secretion involved in immune response 1.065948e-2
GO:0003029 detection of hypoxic conditions in blood by carotid body chemoreceptor signaling 1.065948e-2
GO:0003273 cell migration involved in endocardial cushion formation 1.065948e-2
GO:0014827 intestine smooth muscle contraction 1.065948e-2
GO:0043547 positive regulation of GTPase activity 1.069904e-2
GO:0018108 peptidyl-tyrosine phosphorylation 1.083486e-2
GO:0034276 kynurenic acid biosynthetic process 1.099014e-2
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 1.099014e-2
GO:0019556 histidine catabolic process to glutamate and formamide 1.099014e-2
GO:0060975 cardioblast migration to the midline involved in heart field formation 1.099014e-2
GO:0002534 cytokine production involved in inflammatory response 1.099014e-2
GO:0003259 cardioblast anterior-lateral migration 1.099014e-2
GO:0003210 cardiac atrium formation 1.099014e-2
GO:0002502 peptide antigen assembly with MHC class I protein complex 1.099014e-2
GO:0003236 sinus venosus morphogenesis 1.099014e-2
GO:0018107 peptidyl-threonine phosphorylation 1.132324e-2
GO:0070846 Hsp90 deacetylation 1.135673e-2
GO:0090042 tubulin deacetylation 1.135673e-2
GO:0034162 toll-like receptor 9 signaling pathway 1.135673e-2
GO:0032782 bile acid secretion 1.135673e-2
GO:0034138 toll-like receptor 3 signaling pathway 1.135673e-2
GO:0003096 renal sodium ion transport 1.135673e-2
GO:0015747 urate transport 1.144890e-2
GO:0008612 peptidyl-lysine modification to hypusine 1.144890e-2
GO:0071872 cellular response to epinephrine stimulus 1.160927e-2
GO:0070842 aggresome assembly 1.160927e-2
GO:0002579 positive regulation of antigen processing and presentation 1.173040e-2
GO:0018076 N-terminal peptidyl-lysine acetylation 1.177138e-2
GO:0070233 negative regulation of T cell apoptosis 1.192704e-2
GO:0033235 positive regulation of protein sumoylation 1.214177e-2
GO:0035434 copper ion transmembrane transport 1.214177e-2
GO:0060177 regulation of angiotensin metabolic process 1.229003e-2
GO:0046322 negative regulation of fatty acid oxidation 1.243217e-2
GO:0061013 regulation of mRNA catabolic process 1.262599e-2
GO:0008354 germ cell migration 1.271276e-2
GO:0051693 actin filament capping 1.273729e-2
GO:0046320 regulation of fatty acid oxidation 1.274090e-2
GO:0060286 flagellar cell motility 1.279273e-2
GO:0045713 low-density lipoprotein particle receptor biosynthetic process 1.279273e-2
GO:0071422 succinate transmembrane transport 1.279273e-2
GO:0070256 negative regulation of mucus secretion 1.279273e-2
GO:0006601 creatine biosynthetic process 1.279273e-2
GO:0006994 positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway 1.279273e-2
GO:0015891 siderophore transport 1.279273e-2
GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep 1.279273e-2
GO:0003093 regulation of glomerular filtration 1.302178e-2
GO:0072044 collecting duct development 1.311787e-2
GO:0006694 steroid biosynthetic process 1.336744e-2
GO:0045995 regulation of embryonic development 1.343036e-2
GO:0048260 positive regulation of receptor-mediated endocytosis 1.355984e-2
GO:2000425 regulation of apoptotic cell clearance 1.368502e-2
GO:0014056 regulation of acetylcholine secretion 1.368502e-2
GO:0051261 protein depolymerization 1.368502e-2
GO:0042396 phosphagen biosynthetic process 1.398254e-2
GO:0090116 C-5 methylation of cytosine 1.398254e-2
GO:0035166 post-embryonic hemopoiesis 1.398254e-2
GO:0019058 viral infectious cycle 1.404975e-2
GO:0014040 positive regulation of Schwann cell differentiation 1.415748e-2
GO:0001881 receptor recycling 1.415748e-2
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 1.415748e-2
GO:0043300 regulation of leukocyte degranulation 1.424075e-2
GO:0032353 negative regulation of hormone biosynthetic process 1.426324e-2
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 1.431633e-2
GO:0043653 mitochondrial fragmentation involved in apoptosis 1.439236e-2
GO:0007509 mesoderm migration involved in gastrulation 1.459647e-2
GO:0030834 regulation of actin filament depolymerization 1.482856e-2
GO:0032229 negative regulation of synaptic transmission, GABAergic 1.486061e-2
GO:0061034 olfactory bulb mitral cell layer development 1.494363e-2
GO:0071436 sodium ion export 1.494363e-2
GO:0006288 base-excision repair, DNA ligation 1.494363e-2
GO:0006344 maintenance of chromatin silencing 1.494363e-2
GO:0060466 activation of meiosis involved in egg activation 1.502990e-2
GO:0006030 chitin metabolic process 1.502990e-2
GO:0019722 calcium-mediated signaling 1.507700e-2
GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis 1.535339e-2
GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 1.535339e-2
GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 1.535339e-2
GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 1.535339e-2
GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure 1.535339e-2
GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 1.535339e-2
GO:0006437 tyrosyl-tRNA aminoacylation 1.535339e-2
GO:0030421 defecation 1.535339e-2
GO:0010625 positive regulation of Schwann cell proliferation 1.535339e-2
GO:0034635 glutathione transport 1.535339e-2
GO:0061310 canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development 1.535339e-2
GO:0090007 regulation of mitotic anaphase 1.535339e-2
GO:2000055 positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.535339e-2
GO:0015696 ammonium transport 1.545355e-2
GO:0016090 prenol metabolic process 1.561303e-2
GO:0009798 axis specification 1.576356e-2
GO:0006284 base-excision repair 1.597048e-2
GO:0072111 cell proliferation involved in kidney development 1.604129e-2
GO:0021697 cerebellar cortex formation 1.606045e-2
GO:0045078 positive regulation of interferon-gamma biosynthetic process 1.619261e-2
GO:0070634 transepithelial ammonium transport 1.631916e-2
GO:0007288 sperm axoneme assembly 1.631916e-2
GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein 1.631916e-2
GO:0009150 purine ribonucleotide metabolic process 1.650005e-2
GO:0016458 gene silencing 1.678320e-2
GO:0043089 positive regulation of Cdc42 GTPase activity 1.701595e-2
GO:0018243 protein O-linked glycosylation via threonine 1.728430e-2
GO:0042506 tyrosine phosphorylation of Stat5 protein 1.728430e-2
GO:0018242 protein O-linked glycosylation via serine 1.728430e-2
GO:0018065 protein-cofactor linkage 1.728430e-2
GO:0009166 nucleotide catabolic process 1.734116e-2
GO:0043968 histone H2A acetylation 1.744020e-2
GO:0072172 mesonephric tubule formation 1.750774e-2
GO:0035089 establishment of apical/basal cell polarity 1.750774e-2
GO:0071874 cellular response to norepinephrine stimulus 1.754952e-2
GO:0031999 negative regulation of fatty acid beta-oxidation 1.762627e-2
GO:0002874 regulation of chronic inflammatory response to antigenic stimulus 1.762627e-2
GO:0002030 inhibitory G-protein coupled receptor phosphorylation 1.762627e-2
GO:0040019 positive regulation of embryonic development 1.815229e-2
GO:0072171 mesonephric tubule morphogenesis 1.819747e-2
GO:0034551 mitochondrial respiratory chain complex III assembly 1.834410e-2
GO:0060709 glycogen cell development involved in embryonic placenta development 1.834410e-2
GO:0035752 lysosomal lumen pH elevation 1.834410e-2
GO:0008611 ether lipid biosynthetic process 1.834410e-2
GO:0032342 aldosterone biosynthetic process 1.834410e-2
GO:0000046 autophagic vacuole fusion 1.834410e-2
GO:0001575 globoside metabolic process 1.834410e-2
GO:0042267 natural killer cell mediated cytotoxicity 1.879717e-2
GO:0002643 regulation of tolerance induction 1.950622e-2
GO:0008078 mesodermal cell migration 1.968127e-2
GO:0070366 regulation of hepatocyte differentiation 1.969963e-2
GO:0060433 bronchus development 1.989908e-2
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 2.000365e-2
GO:0007017 microtubule-based process 2.010731e-2
GO:0090002 establishment of protein localization in plasma membrane 2.014750e-2
GO:0045819 positive regulation of glycogen catabolic process 2.014750e-2
GO:0006359 regulation of transcription from RNA polymerase III promoter 2.074628e-2
GO:0006195 purine nucleotide catabolic process 2.093139e-2
GO:0045218 zonula adherens maintenance 2.095420e-2
GO:0048599 oocyte development 2.112307e-2
GO:0048842 positive regulation of axon extension involved in axon guidance 2.112611e-2
GO:0060988 lipid tube assembly 2.112611e-2
GO:0006669 sphinganine-1-phosphate biosynthetic process 2.112611e-2
GO:0072655 establishment of protein localization in mitochondrion 2.122506e-2
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 2.144624e-2
GO:0021547 midbrain-hindbrain boundary initiation 2.162783e-2
GO:0021754 facial nucleus development 2.162783e-2