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Novel motif:152

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name:motif152_GCKYRMKCGS

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0043503 skeletal muscle fiber adaptation 4.136719e-19
GO:0006353 transcription termination, DNA-dependent 5.194544e-14
GO:0006361 transcription initiation from RNA polymerase I promoter 1.234050e-11
GO:0097039 protein linear polyubiquitination 9.850537e-11
GO:0016233 telomere capping 4.808562e-10
GO:0006363 termination of RNA polymerase I transcription 7.935586e-10
GO:0031848 protection from non-homologous end joining at telomere 2.125455e-9
GO:0001510 RNA methylation 2.402330e-9
GO:0006268 DNA unwinding involved in replication 2.601803e-9
GO:0030262 apoptotic nuclear change 5.182643e-9
GO:0006481 C-terminal protein methylation 7.789109e-9
GO:0034470 ncRNA processing 9.721218e-9
GO:0022601 menstrual cycle phase 1.836464e-8
GO:0006369 termination of RNA polymerase II transcription 3.093138e-8
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 3.788385e-8
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 3.882645e-8
GO:0060976 coronary vasculature development 5.720929e-8
GO:0019101 female somatic sex determination 5.767414e-8
GO:0042703 menstruation 5.767414e-8
GO:0006362 transcription elongation from RNA polymerase I promoter 6.158375e-8
GO:0060381 positive regulation of single-stranded telomeric DNA binding 6.875699e-8
GO:0006308 DNA catabolic process 7.329302e-8
GO:0021892 cerebral cortex GABAergic interneuron differentiation 8.283699e-8
GO:0043501 skeletal muscle adaptation 1.031325e-7
GO:0042254 ribosome biogenesis 1.234740e-7
GO:0042696 menarche 1.383477e-7
GO:0006360 transcription from RNA polymerase I promoter 2.208025e-7
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 2.270195e-7
GO:0016570 histone modification 2.729764e-7
GO:0033084 regulation of immature T cell proliferation in thymus 4.908539e-7
GO:0035470 positive regulation of vascular wound healing 4.960355e-7
GO:0006189 'de novo' IMP biosynthetic process 6.420697e-7
GO:0006188 IMP biosynthetic process 8.798122e-7
GO:0009451 RNA modification 8.843197e-7
GO:0008635 activation of caspase activity by cytochrome c 1.016414e-6
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 1.028811e-6
GO:0048102 autophagic cell death 1.043415e-6
GO:0006281 DNA repair 1.352413e-6
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 1.356539e-6
GO:0002074 extraocular skeletal muscle development 1.375720e-6
GO:0030237 female sex determination 1.438799e-6
GO:0045007 depurination 1.736123e-6
GO:0016569 covalent chromatin modification 1.801150e-6
GO:0048561 establishment of organ orientation 1.909368e-6
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 1.919565e-6
GO:0016578 histone deubiquitination 1.980996e-6
GO:0007051 spindle organization 2.056990e-6
GO:0021759 globus pallidus development 2.400471e-6
GO:0006398 histone mRNA 3'-end processing 2.511989e-6
GO:0043923 positive regulation by host of viral transcription 3.270502e-6
GO:0006482 protein demethylation 3.739833e-6
GO:0006356 regulation of transcription from RNA polymerase I promoter 4.008594e-6
GO:0046607 positive regulation of centrosome cycle 4.581943e-6
GO:0070194 synaptonemal complex disassembly 5.425732e-6
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 5.425732e-6
GO:0051645 Golgi localization 5.522602e-6
GO:0060430 lung saccule development 6.639839e-6
GO:0003329 pancreatic PP cell fate commitment 9.581373e-6
GO:0003326 pancreatic A cell fate commitment 9.581373e-6
GO:0070979 protein K11-linked ubiquitination 1.048292e-5
GO:0050434 positive regulation of viral transcription 1.068811e-5
GO:0000731 DNA synthesis involved in DNA repair 1.081313e-5
GO:0042538 hyperosmotic salinity response 1.083730e-5
GO:0033083 regulation of immature T cell proliferation 1.100359e-5
GO:0006420 arginyl-tRNA aminoacylation 1.157456e-5
GO:0090141 positive regulation of mitochondrial fission 1.198188e-5
GO:0043543 protein acylation 1.393533e-5
GO:0006473 protein acetylation 1.422129e-5
GO:0061003 positive regulation of dendritic spine morphogenesis 1.435271e-5
GO:0042407 cristae formation 1.529552e-5
GO:0046939 nucleotide phosphorylation 1.742521e-5
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.901573e-5
GO:0000056 ribosomal small subunit export from nucleus 1.959079e-5
GO:0008033 tRNA processing 2.066395e-5
GO:0006261 DNA-dependent DNA replication 2.119052e-5
GO:0003310 pancreatic A cell differentiation 2.285310e-5
GO:2000465 regulation of glycogen (starch) synthase activity 2.306914e-5
GO:0060580 ventral spinal cord interneuron fate determination 2.536574e-5
GO:0003327 type B pancreatic cell fate commitment 2.536574e-5
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.773616e-5
GO:0009155 purine deoxyribonucleotide catabolic process 2.888306e-5
GO:0048050 post-embryonic eye morphogenesis 3.082589e-5
GO:0000022 mitotic spindle elongation 3.245537e-5
GO:0018026 peptidyl-lysine monomethylation 3.544556e-5
GO:0046604 positive regulation of mitotic centrosome separation 3.879909e-5
GO:0090305 nucleic acid phosphodiester bond hydrolysis 3.947687e-5
GO:0016577 histone demethylation 4.033024e-5
GO:0021895 cerebral cortex neuron differentiation 4.117869e-5
GO:0006285 base-excision repair, AP site formation 4.184898e-5
GO:0070537 histone H2A K63-linked deubiquitination 4.898858e-5
GO:0033342 negative regulation of collagen binding 5.044464e-5
GO:0051898 negative regulation of protein kinase B signaling cascade 5.329238e-5
GO:0061157 mRNA destabilization 5.336005e-5
GO:0002536 respiratory burst involved in inflammatory response 5.336005e-5
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 5.336005e-5
GO:0006475 internal protein amino acid acetylation 5.721117e-5
GO:0000154 rRNA modification 5.884427e-5
GO:0007288 sperm axoneme assembly 5.915604e-5
GO:0021986 habenula development 6.216613e-5
GO:0033088 negative regulation of immature T cell proliferation in thymus 6.687540e-5
GO:0032211 negative regulation of telomere maintenance via telomerase 7.805693e-5
GO:0046782 regulation of viral transcription 8.598602e-5
GO:0035306 positive regulation of dephosphorylation 9.139961e-5
GO:0007141 male meiosis I 1.075249e-4
GO:0018393 internal peptidyl-lysine acetylation 1.082805e-4
GO:0030953 astral microtubule organization 1.089662e-4
GO:0016072 rRNA metabolic process 1.137112e-4
GO:0018394 peptidyl-lysine acetylation 1.137802e-4
GO:0035307 positive regulation of protein dephosphorylation 1.155524e-4
GO:2001037 positive regulation of tongue muscle cell differentiation 1.183020e-4
GO:0060982 coronary artery morphogenesis 1.183020e-4
GO:0097152 mesenchymal cell apoptosis 1.183020e-4
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 1.372615e-4
GO:0016573 histone acetylation 1.467167e-4
GO:0035304 regulation of protein dephosphorylation 1.570030e-4
GO:0051324 prophase 1.650074e-4
GO:0009113 purine base biosynthetic process 1.700764e-4
GO:0006364 rRNA processing 1.747153e-4
GO:0018993 somatic sex determination 1.750282e-4
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 1.979217e-4
GO:0010498 proteasomal protein catabolic process 2.121151e-4
GO:0030513 positive regulation of BMP signaling pathway 2.153924e-4
GO:0030422 production of siRNA involved in RNA interference 2.325166e-4
GO:0072111 cell proliferation involved in kidney development 2.342444e-4
GO:0006538 glutamate catabolic process 2.370675e-4
GO:0046628 positive regulation of insulin receptor signaling pathway 2.472697e-4
GO:0071897 DNA biosynthetic process 2.599431e-4
GO:0018027 peptidyl-lysine dimethylation 2.699334e-4
GO:0090140 regulation of mitochondrial fission 2.777986e-4
GO:0045342 MHC class II biosynthetic process 2.795080e-4
GO:0070839 divalent metal ion export 2.795080e-4
GO:0043091 L-arginine import 2.795080e-4
GO:0015707 nitrite transport 2.795080e-4
GO:0006876 cellular cadmium ion homeostasis 2.795080e-4
GO:0032632 interleukin-3 production 2.795080e-4
GO:0000414 regulation of histone H3-K36 methylation 2.909625e-4
GO:0032392 DNA geometric change 2.936978e-4
GO:0090307 spindle assembly involved in mitosis 3.024683e-4
GO:0071166 ribonucleoprotein complex localization 3.112524e-4
GO:0006680 glucosylceramide catabolic process 3.112524e-4
GO:0030488 tRNA methylation 3.177422e-4
GO:0014044 Schwann cell development 3.202440e-4
GO:0065001 specification of axis polarity 3.287085e-4
GO:0018022 peptidyl-lysine methylation 3.359650e-4
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 3.507582e-4
GO:0060486 Clara cell differentiation 3.651035e-4
GO:0007020 microtubule nucleation 3.651035e-4
GO:0021526 medial motor column neuron differentiation 3.700886e-4
GO:0002309 T cell proliferation involved in immune response 3.700886e-4
GO:0032508 DNA duplex unwinding 3.888396e-4
GO:0006284 base-excision repair 3.926219e-4
GO:0009264 deoxyribonucleotide catabolic process 3.955420e-4
GO:0006013 mannose metabolic process 3.978850e-4
GO:0043921 modulation by host of viral transcription 4.195626e-4
GO:0030423 targeting of mRNA for destruction involved in RNA interference 4.258879e-4
GO:0002003 angiotensin maturation 4.258879e-4
GO:0021903 rostrocaudal neural tube patterning 4.310024e-4
GO:0009151 purine deoxyribonucleotide metabolic process 4.320139e-4
GO:0060711 labyrinthine layer development 4.480469e-4
GO:2000370 positive regulation of clathrin-mediated endocytosis 4.705224e-4
GO:0071169 establishment of protein localization to chromatin 4.705224e-4
GO:0006844 acyl carnitine transport 4.705224e-4
GO:0030828 positive regulation of cGMP biosynthetic process 4.771744e-4
GO:0000088 mitotic prophase 5.047175e-4
GO:0016568 chromatin modification 5.156095e-4
GO:0070193 synaptonemal complex organization 5.237289e-4
GO:0070625 zymogen granule exocytosis 5.242791e-4
GO:0060179 male mating behavior 5.442758e-4
GO:0051586 positive regulation of dopamine uptake 5.603973e-4
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 5.603973e-4
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 5.603973e-4
GO:0035090 maintenance of apical/basal cell polarity 5.795414e-4
GO:0022011 myelination in peripheral nervous system 5.809080e-4
GO:0001830 trophectodermal cell fate commitment 6.596397e-4
GO:0033299 secretion of lysosomal enzymes 6.615733e-4
GO:0051365 cellular response to potassium ion starvation 7.315886e-4
GO:0046796 viral genome transport in host cell 7.315886e-4
GO:0042255 ribosome assembly 7.609916e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 7.761962e-4
GO:0045657 positive regulation of monocyte differentiation 8.151243e-4
GO:0006406 mRNA export from nucleus 8.187105e-4
GO:0009452 RNA capping 8.194971e-4
GO:0000415 negative regulation of histone H3-K36 methylation 8.575187e-4
GO:0048343 paraxial mesodermal cell fate commitment 8.795748e-4
GO:0043988 histone H3-S28 phosphorylation 8.831469e-4
GO:0070105 positive regulation of interleukin-6-mediated signaling pathway 8.831469e-4
GO:0043987 histone H3-S10 phosphorylation 8.831469e-4
GO:0014037 Schwann cell differentiation 8.988619e-4
GO:0021592 fourth ventricle development 9.097827e-4
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 9.253933e-4
GO:0001522 pseudouridine synthesis 9.253933e-4
GO:0032784 regulation of transcription elongation, DNA-dependent 9.267410e-4
GO:0034502 protein localization to chromosome 9.344818e-4
GO:0034770 histone H4-K20 methylation 9.609924e-4
GO:0071394 cellular response to testosterone stimulus 9.654448e-4
GO:0016598 protein arginylation 1.037328e-3
GO:0042942 D-serine transport 1.037328e-3
GO:0046112 nucleobase biosynthetic process 1.056049e-3
GO:0070934 CRD-mediated mRNA stabilization 1.083124e-3
GO:0033092 positive regulation of immature T cell proliferation in thymus 1.098982e-3
GO:0007128 meiotic prophase I 1.113157e-3
GO:0014888 striated muscle adaptation 1.116833e-3
GO:0060816 random inactivation of X chromosome 1.141782e-3
GO:0009262 deoxyribonucleotide metabolic process 1.175512e-3
GO:0035461 vitamin transmembrane transport 1.180056e-3
GO:0001946 lymphangiogenesis 1.201032e-3
GO:0065002 intracellular protein transmembrane transport 1.206112e-3
GO:0006220 pyrimidine nucleotide metabolic process 1.229042e-3
GO:0010626 negative regulation of Schwann cell proliferation 1.229821e-3
GO:0018205 peptidyl-lysine modification 1.235827e-3
GO:0022027 interkinetic nuclear migration 1.240191e-3
GO:0070079 histone H4-R3 demethylation 1.262223e-3
GO:0070078 histone H3-R2 demethylation 1.262223e-3
GO:0015787 UDP-glucuronic acid transport 1.262223e-3
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 1.262223e-3
GO:0015789 UDP-N-acetylgalactosamine transport 1.262223e-3
GO:0031627 telomeric loop formation 1.263213e-3
GO:0031468 nuclear envelope reassembly 1.263213e-3
GO:0001842 neural fold formation 1.303682e-3
GO:0051572 negative regulation of histone H3-K4 methylation 1.377655e-3
GO:0048846 axon extension involved in axon guidance 1.451767e-3
GO:0021528 commissural neuron differentiation in spinal cord 1.484989e-3
GO:0014707 branchiomeric skeletal muscle development 1.515449e-3
GO:0006513 protein monoubiquitination 1.586305e-3
GO:0035137 hindlimb morphogenesis 1.603405e-3
GO:0031118 rRNA pseudouridine synthesis 1.605730e-3
GO:0042747 circadian sleep/wake cycle, REM sleep 1.605730e-3
GO:0070922 small RNA loading onto RISC 1.641718e-3
GO:0016140 O-glycoside metabolic process 1.643376e-3
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1.656733e-3
GO:0052565 response to defense-related host nitric oxide production 1.697680e-3
GO:0006289 nucleotide-excision repair 1.706583e-3
GO:0009394 2'-deoxyribonucleotide metabolic process 1.721071e-3
GO:2000573 positive regulation of DNA biosynthetic process 1.727298e-3
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 1.742920e-3
GO:0006370 mRNA capping 1.752637e-3
GO:0042273 ribosomal large subunit biogenesis 1.816385e-3
GO:0035518 histone H2A monoubiquitination 1.817194e-3
GO:0060014 granulosa cell differentiation 1.830523e-3
GO:0045199 maintenance of epithelial cell apical/basal polarity 1.858222e-3
GO:0034227 tRNA thio-modification 1.890228e-3
GO:0002098 tRNA wobble uridine modification 1.890228e-3
GO:0002069 columnar/cuboidal epithelial cell maturation 1.890228e-3
GO:0072203 cell proliferation involved in metanephros development 1.969451e-3
GO:0006241 CTP biosynthetic process 1.975941e-3
GO:0042149 cellular response to glucose starvation 2.029199e-3
GO:0072298 regulation of metanephric glomerulus development 2.094157e-3
GO:0031167 rRNA methylation 2.122459e-3
GO:0030174 regulation of DNA-dependent DNA replication initiation 2.209212e-3
GO:0070170 regulation of tooth mineralization 2.211364e-3
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 2.278133e-3
GO:0042637 catagen 2.278133e-3
GO:0060236 regulation of mitotic spindle organization 2.332793e-3
GO:0006540 glutamate decarboxylation to succinate 2.332793e-3
GO:0000239 pachytene 2.392874e-3
GO:0001844 protein insertion into mitochondrial membrane involved in induction of apoptosis 2.400101e-3
GO:0031133 regulation of axon diameter 2.405398e-3
GO:0017145 stem cell division 2.487761e-3
GO:0046676 negative regulation of insulin secretion 2.490544e-3
GO:0070198 protein localization to chromosome, telomeric region 2.499504e-3
GO:0001840 neural plate development 2.631701e-3
GO:0006354 transcription elongation, DNA-dependent 2.643388e-3
GO:0070534 protein K63-linked ubiquitination 2.670647e-3
GO:2000466 negative regulation of glycogen (starch) synthase activity 2.685083e-3
GO:0006529 asparagine biosynthetic process 2.726668e-3
GO:0006396 RNA processing 2.809078e-3
GO:0014040 positive regulation of Schwann cell differentiation 2.923286e-3
GO:0048665 neuron fate specification 2.969191e-3
GO:0006901 vesicle coating 2.969691e-3
GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process 2.996014e-3
GO:0034401 regulation of transcription by chromatin organization 2.996014e-3
GO:0008298 intracellular mRNA localization 3.063252e-3
GO:0051567 histone H3-K9 methylation 3.133709e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 3.157971e-3
GO:0006183 GTP biosynthetic process 3.346231e-3
GO:0006228 UTP biosynthetic process 3.346231e-3
GO:0006165 nucleoside diphosphate phosphorylation 3.346231e-3
GO:0010070 zygote asymmetric cell division 3.354972e-3
GO:0090278 negative regulation of peptide hormone secretion 3.359764e-3
GO:0006298 mismatch repair 3.361268e-3
GO:0048341 paraxial mesoderm formation 3.480158e-3
GO:0072393 microtubule anchoring at microtubule organizing center 3.529144e-3
GO:0006405 RNA export from nucleus 3.539237e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 3.689678e-3
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 3.741921e-3
GO:0006313 transposition, DNA-mediated 3.804527e-3
GO:0032210 regulation of telomere maintenance via telomerase 3.810251e-3
GO:0007063 regulation of sister chromatid cohesion 3.810251e-3
GO:0060576 intestinal epithelial cell development 3.853709e-3
GO:0051414 response to cortisol stimulus 3.984468e-3
GO:2000002 negative regulation of DNA damage checkpoint 4.249075e-3
GO:0021588 cerebellum formation 4.249075e-3
GO:0022004 midbrain-hindbrain boundary maturation during brain development 4.249075e-3
GO:0006843 mitochondrial citrate transport 4.249075e-3
GO:0021551 central nervous system morphogenesis 4.249075e-3
GO:0048597 post-embryonic camera-type eye morphogenesis 4.426701e-3
GO:0051089 constitutive protein ectodomain proteolysis 4.426701e-3
GO:0046674 induction of retinal programmed cell death 4.426701e-3
GO:0002352 B cell negative selection 4.426701e-3
GO:0032976 release of matrix enzymes from mitochondria 4.426701e-3
GO:0001777 T cell homeostatic proliferation 4.426701e-3
GO:0008052 sensory organ boundary specification 4.426701e-3
GO:0048280 vesicle fusion with Golgi apparatus 4.514567e-3
GO:0006287 base-excision repair, gap-filling 4.514567e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 4.515561e-3
GO:0060574 intestinal epithelial cell maturation 4.520128e-3
GO:0035356 cellular triglyceride homeostasis 4.520128e-3
GO:0042069 regulation of catecholamine metabolic process 4.655320e-3
GO:0007140 male meiosis 4.703542e-3
GO:0016574 histone ubiquitination 4.760678e-3
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 4.771653e-3
GO:0035095 behavioral response to nicotine 4.837418e-3
GO:0006659 phosphatidylserine biosynthetic process 4.837418e-3
GO:0034660 ncRNA metabolic process 4.975572e-3
GO:0048291 isotype switching to IgG isotypes 5.011351e-3
GO:0018364 peptidyl-glutamine methylation 5.011351e-3
GO:0090324 negative regulation of oxidative phosphorylation 5.011351e-3
GO:0002368 B cell cytokine production 5.011351e-3
GO:0002842 positive regulation of T cell mediated immune response to tumor cell 5.011351e-3
GO:0010255 glucose mediated signaling pathway 5.011351e-3
GO:0051225 spindle assembly 5.087066e-3
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 5.227642e-3
GO:0071934 thiamine transmembrane transport 5.260678e-3
GO:0035522 monoubiquitinated histone H2A deubiquitination 5.260678e-3
GO:0061144 alveolar secondary septum development 5.260678e-3
GO:0033169 histone H3-K9 demethylation 5.302430e-3
GO:0016246 RNA interference 5.329842e-3
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 5.378213e-3
GO:0031860 telomeric 3' overhang formation 5.378213e-3
GO:0042117 monocyte activation 5.525147e-3
GO:0061181 regulation of chondrocyte development 5.638916e-3
GO:0007035 vacuolar acidification 5.693832e-3
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 5.740165e-3
GO:0032205 negative regulation of telomere maintenance 5.807529e-3
GO:0032536 regulation of cell projection size 6.023705e-3
GO:0019086 late viral mRNA transcription 6.048463e-3
GO:0048103 somatic stem cell division 6.063969e-3
GO:0021993 initiation of neural tube closure 6.102905e-3
GO:0006352 transcription initiation, DNA-dependent 6.276966e-3
GO:0006892 post-Golgi vesicle-mediated transport 6.296476e-3
GO:0048268 clathrin coat assembly 6.313948e-3
GO:0021843 substrate-independent telencephalic tangential interneuron migration 6.333500e-3
GO:0043414 macromolecule methylation 6.335028e-3
GO:0048524 positive regulation of viral reproduction 6.442401e-3
GO:0006734 NADH metabolic process 6.588151e-3
GO:0021853 cerebral cortex GABAergic interneuron migration 6.724109e-3
GO:0043922 negative regulation by host of viral transcription 6.748785e-3
GO:0050775 positive regulation of dendrite morphogenesis 6.775899e-3
GO:0021644 vagus nerve morphogenesis 6.782878e-3
GO:0042766 nucleosome mobilization 6.887831e-3
GO:0070171 negative regulation of tooth mineralization 6.900902e-3
GO:0010430 fatty acid omega-oxidation 6.926607e-3
GO:0032915 positive regulation of transforming growth factor beta2 production 6.937243e-3
GO:0071279 cellular response to cobalt ion 6.937243e-3
GO:0010637 negative regulation of mitochondrial fusion 6.937243e-3
GO:0015969 guanosine tetraphosphate metabolic process 6.937243e-3
GO:0007100 mitotic centrosome separation 6.937243e-3
GO:0006528 asparagine metabolic process 6.972760e-3
GO:0006325 chromatin organization 6.985994e-3
GO:0060716 labyrinthine layer blood vessel development 7.013825e-3
GO:0060347 heart trabecula formation 7.026298e-3
GO:0072528 pyrimidine-containing compound biosynthetic process 7.387085e-3
GO:0003148 outflow tract septum morphogenesis 7.527989e-3
GO:0045351 type I interferon biosynthetic process 8.102990e-3
GO:0035026 leading edge cell differentiation 8.114463e-3
GO:0031914 negative regulation of synaptic plasticity 8.260165e-3
GO:0002635 negative regulation of germinal center formation 8.260165e-3
GO:0035329 hippo signaling cascade 8.285480e-3
GO:0043966 histone H3 acetylation 8.429260e-3
GO:0033091 positive regulation of immature T cell proliferation 8.479980e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 8.500411e-3
GO:0051443 positive regulation of ubiquitin-protein ligase activity 8.550930e-3
GO:0021871 forebrain regionalization 8.733363e-3
GO:0021819 layer formation in cerebral cortex 9.062505e-3
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development 9.086225e-3
GO:0051882 mitochondrial depolarization 9.086225e-3
GO:0003061 positive regulation of the force of heart contraction by norepinephrine 9.086225e-3
GO:0016142 O-glycoside catabolic process 9.086225e-3
GO:0018283 iron incorporation into metallo-sulfur cluster 9.094005e-3
GO:0034214 protein hexamerization 9.122966e-3
GO:2000119 negative regulation of sodium-dependent phosphate transport 9.290194e-3
GO:0006478 peptidyl-tyrosine sulfation 9.290194e-3
GO:2000016 negative regulation of determination of dorsal identity 9.290194e-3
GO:0048752 semicircular canal morphogenesis 9.301171e-3
GO:0090344 negative regulation of cell aging 9.398182e-3
GO:0006119 oxidative phosphorylation 9.410661e-3
GO:0014038 regulation of Schwann cell differentiation 9.745680e-3
GO:0006283 transcription-coupled nucleotide-excision repair 1.005350e-2
GO:0045986 negative regulation of smooth muscle contraction 1.035120e-2
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1.035120e-2
GO:0070988 demethylation 1.052151e-2
GO:0061384 heart trabecular morphogenesis 1.063362e-2
GO:0060061 Spemann organizer formation 1.090252e-2
GO:0021997 neural plate axis specification 1.090252e-2
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 1.090252e-2
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 1.090252e-2
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.090708e-2
GO:0050935 iridophore differentiation 1.092120e-2
GO:0048937 lateral line nerve glial cell development 1.092120e-2
GO:0000079 regulation of cyclin-dependent protein kinase activity 1.109573e-2
GO:0071549 cellular response to dexamethasone stimulus 1.116217e-2
GO:0046731 passive induction of host immune response by virus 1.121207e-2
GO:0021511 spinal cord patterning 1.136102e-2
GO:0021985 neurohypophysis development 1.138038e-2
GO:0070076 histone lysine demethylation 1.141191e-2
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 1.142154e-2
GO:0006400 tRNA modification 1.143238e-2
GO:0043174 nucleoside salvage 1.167782e-2
GO:0042417 dopamine metabolic process 1.172726e-2
GO:0032298 positive regulation of DNA-dependent DNA replication initiation 1.175062e-2
GO:0090303 positive regulation of wound healing 1.192711e-2
GO:0051584 regulation of dopamine uptake 1.192711e-2
GO:0060087 relaxation of vascular smooth muscle 1.192880e-2
GO:0060167 regulation of adenosine receptor signaling pathway 1.199644e-2
GO:0045655 regulation of monocyte differentiation 1.243829e-2
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.255134e-2
GO:0060837 blood vessel endothelial cell differentiation 1.271580e-2
GO:0034776 response to histamine 1.271580e-2
GO:0071072 negative regulation of phospholipid biosynthetic process 1.278441e-2
GO:0006102 isocitrate metabolic process 1.278441e-2
GO:0002031 G-protein coupled receptor internalization 1.303611e-2
GO:0090192 regulation of glomerulus development 1.304929e-2
GO:0051438 regulation of ubiquitin-protein ligase activity 1.323740e-2
GO:0021707 cerebellar granule cell differentiation 1.342876e-2
GO:0021877 forebrain neuron fate commitment 1.351290e-2
GO:0048486 parasympathetic nervous system development 1.351795e-2
GO:0051096 positive regulation of helicase activity 1.361165e-2
GO:0016567 protein ubiquitination 1.365059e-2
GO:2000077 negative regulation of type B pancreatic cell development 1.385058e-2
GO:0030421 defecation 1.385058e-2
GO:0009060 aerobic respiration 1.428338e-2
GO:0045046 protein import into peroxisome membrane 1.439224e-2
GO:0007023 post-chaperonin tubulin folding pathway 1.439224e-2
GO:0009147 pyrimidine nucleoside triphosphate metabolic process 1.455790e-2
GO:0031017 exocrine pancreas development 1.455899e-2
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1.458999e-2
GO:2001054 negative regulation of mesenchymal cell apoptosis 1.467318e-2
GO:0009258 10-formyltetrahydrofolate catabolic process 1.467318e-2
GO:0070179 D-serine biosynthetic process 1.480942e-2
GO:0042780 tRNA 3'-end processing 1.480942e-2
GO:0071105 response to interleukin-11 1.480942e-2
GO:0080009 mRNA methylation 1.480942e-2
GO:0008049 male courtship behavior 1.480942e-2
GO:0023035 CD40 signaling pathway 1.480942e-2
GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA 1.480942e-2
GO:0051204 protein insertion into mitochondrial membrane 1.482652e-2
GO:0009051 pentose-phosphate shunt, oxidative branch 1.523725e-2
GO:0016571 histone methylation 1.523982e-2
GO:0021586 pons maturation 1.527064e-2
GO:0070602 regulation of centromeric sister chromatid cohesion 1.539160e-2
GO:0070734 histone H3-K27 methylation 1.558624e-2
GO:2000143 negative regulation of transcription initiation, DNA-dependent 1.558979e-2
GO:0009798 axis specification 1.561812e-2
GO:0042053 regulation of dopamine metabolic process 1.564892e-2
GO:0071071 regulation of phospholipid biosynthetic process 1.565709e-2
GO:0070574 cadmium ion transmembrane transport 1.565709e-2
GO:0051168 nuclear export 1.573317e-2
GO:0060947 cardiac vascular smooth muscle cell differentiation 1.574388e-2
GO:0043173 nucleotide salvage 1.574388e-2
GO:0046015 regulation of transcription by glucose 1.610346e-2
GO:0021506 anterior neuropore closure 1.614074e-2
GO:0001975 response to amphetamine 1.618661e-2
GO:0042487 regulation of odontogenesis of dentine-containing tooth 1.665659e-2
GO:0021523 somatic motor neuron differentiation 1.667136e-2
GO:0060968 regulation of gene silencing 1.678864e-2
GO:0043654 recognition of apoptotic cell 1.680617e-2
GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 1.698319e-2
GO:0034551 mitochondrial respiratory chain complex III assembly 1.698319e-2
GO:0060764 cell-cell signaling involved in mammary gland development 1.698319e-2
GO:0051984 positive regulation of chromosome segregation 1.698319e-2
GO:0090104 pancreatic E cell differentiation 1.716209e-2
GO:0003311 pancreatic D cell differentiation 1.716209e-2
GO:0030393 fructoselysine metabolic process 1.716209e-2
GO:0008355 olfactory learning 1.730905e-2
GO:0021530 spinal cord oligodendrocyte cell fate specification 1.737907e-2
GO:0072109 glomerular mesangium development 1.754119e-2
GO:0051684 maintenance of Golgi location 1.756637e-2
GO:0060847 endothelial cell fate specification 1.756637e-2
GO:0046670 positive regulation of retinal cell programmed cell death 1.756637e-2
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production 1.756637e-2
GO:0010509 polyamine homeostasis 1.756637e-2
GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway 1.756637e-2
GO:0032077 positive regulation of deoxyribonuclease activity 1.756637e-2
GO:0009236 cobalamin biosynthetic process 1.756637e-2
GO:0032738 positive regulation of interleukin-15 production 1.756637e-2
GO:0009226 nucleotide-sugar biosynthetic process 1.761841e-2
GO:0051351 positive regulation of ligase activity 1.763403e-2
GO:0032288 myelin assembly 1.846980e-2
GO:0016340 calcium-dependent cell-matrix adhesion 1.877763e-2
GO:0006168 adenine salvage 1.877763e-2
GO:0034447 very-low-density lipoprotein particle clearance 1.902064e-2
GO:0033058 directional locomotion 1.951534e-2
GO:0046984 regulation of hemoglobin biosynthetic process 1.978541e-2
GO:0046349 amino sugar biosynthetic process 1.978581e-2
GO:0043951 negative regulation of cAMP-mediated signaling 1.986776e-2
GO:0033081 regulation of T cell differentiation in thymus 1.988070e-2
GO:0006610 ribosomal protein import into nucleus 1.996274e-2
GO:0021678 third ventricle development 2.034765e-2
GO:0007500 mesodermal cell fate determination 2.056452e-2
GO:0070857 regulation of bile acid biosynthetic process 2.064997e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0010467 gene expression 7.841309e-16
GO:0016070 RNA metabolic process 7.008780e-14
GO:0044260 cellular macromolecule metabolic process 1.712166e-12
GO:0090304 nucleic acid metabolic process 1.729430e-12
GO:0032774 RNA biosynthetic process 1.252482e-11
GO:0006351 transcription, DNA-dependent 1.379619e-11
GO:0051276 chromosome organization 1.098414e-10
GO:0006325 chromatin organization 1.459416e-10
GO:0006139 nucleobase-containing compound metabolic process 3.030072e-10
GO:0006403 RNA localization 4.191858e-10
GO:0034645 cellular macromolecule biosynthetic process 1.435791e-9
GO:0016568 chromatin modification 3.254199e-9
GO:0000279 M phase 9.281504e-9
GO:0050658 RNA transport 1.355889e-8
GO:2000772 regulation of cellular senescence 1.516380e-8
GO:0043653 mitochondrial fragmentation involved in apoptosis 1.642360e-8
GO:0016567 protein ubiquitination 2.648114e-8
GO:0009059 macromolecule biosynthetic process 4.355342e-8
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 4.396447e-8
GO:0070534 protein K63-linked ubiquitination 4.828601e-8
GO:0022403 cell cycle phase 5.705439e-8
GO:0021549 cerebellum development 6.007492e-8
GO:0016458 gene silencing 6.387496e-8
GO:0070079 histone H4-R3 demethylation 6.860059e-8
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 6.860059e-8
GO:0070078 histone H3-R2 demethylation 6.860059e-8
GO:0032446 protein modification by small protein conjugation 7.117109e-8
GO:0046985 positive regulation of hemoglobin biosynthetic process 8.786627e-8
GO:0043973 histone H3-K4 acetylation 8.786627e-8
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 8.786627e-8
GO:0006511 ubiquitin-dependent protein catabolic process 2.300715e-7
GO:0043632 modification-dependent macromolecule catabolic process 2.828067e-7
GO:0006188 IMP biosynthetic process 2.996176e-7
GO:0019941 modification-dependent protein catabolic process 3.073647e-7
GO:0018279 protein N-linked glycosylation via asparagine 3.238230e-7
GO:0022037 metencephalon development 3.540067e-7
GO:0031507 heterochromatin formation 4.233972e-7
GO:0046984 regulation of hemoglobin biosynthetic process 4.690027e-7
GO:0090224 regulation of spindle organization 5.168211e-7
GO:0051028 mRNA transport 7.796208e-7
GO:0070647 protein modification by small protein conjugation or removal 8.054473e-7
GO:0045647 negative regulation of erythrocyte differentiation 1.008824e-6
GO:0007051 spindle organization 1.031756e-6
GO:0042053 regulation of dopamine metabolic process 1.186903e-6
GO:0001843 neural tube closure 1.202594e-6
GO:0034470 ncRNA processing 1.550723e-6
GO:0070936 protein K48-linked ubiquitination 1.991691e-6
GO:2000774 positive regulation of cellular senescence 2.646518e-6
GO:0090402 oncogene-induced senescence 2.646518e-6
GO:0035986 senescence-associated heterochromatin focus formation 2.646518e-6
GO:0048368 lateral mesoderm development 2.807290e-6
GO:0046605 regulation of centrosome cycle 3.340847e-6
GO:0051603 proteolysis involved in cellular protein catabolic process 3.450337e-6
GO:0030902 hindbrain development 3.496451e-6
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 4.240285e-6
GO:0042069 regulation of catecholamine metabolic process 4.316467e-6
GO:0045964 positive regulation of dopamine metabolic process 4.358857e-6
GO:0031047 gene silencing by RNA 4.403264e-6
GO:0031508 centromeric heterochromatin formation 4.585417e-6
GO:0060606 tube closure 5.687179e-6
GO:0016072 rRNA metabolic process 5.844301e-6
GO:0021695 cerebellar cortex development 6.277645e-6
GO:0022402 cell cycle process 6.641174e-6
GO:0034508 centromere complex assembly 8.341757e-6
GO:0034660 ncRNA metabolic process 9.634618e-6
GO:0051321 meiotic cell cycle 1.041715e-5
GO:0007049 cell cycle 1.117304e-5
GO:0051586 positive regulation of dopamine uptake 1.194277e-5
GO:0051252 regulation of RNA metabolic process 1.312384e-5
GO:0006184 GTP catabolic process 1.346449e-5
GO:0045585 positive regulation of cytotoxic T cell differentiation 1.408269e-5
GO:0030163 protein catabolic process 1.511674e-5
GO:0006396 RNA processing 1.590188e-5
GO:0048285 organelle fission 1.661249e-5
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 1.676468e-5
GO:0018293 protein-FAD linkage 1.676468e-5
GO:0044257 cellular protein catabolic process 1.697694e-5
GO:0018205 peptidyl-lysine modification 1.830000e-5
GO:0014020 primary neural tube formation 2.196329e-5
GO:0046039 GTP metabolic process 2.278134e-5
GO:0009798 axis specification 2.281174e-5
GO:0043094 cellular metabolic compound salvage 2.669059e-5
GO:0015780 nucleotide-sugar transport 3.001094e-5
GO:0030865 cortical cytoskeleton organization 3.080239e-5
GO:0006449 regulation of translational termination 3.102998e-5
GO:0006364 rRNA processing 3.151278e-5
GO:0035194 posttranscriptional gene silencing by RNA 3.285328e-5
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 3.354454e-5
GO:0002098 tRNA wobble uridine modification 3.452527e-5
GO:0051382 kinetochore assembly 3.918344e-5
GO:0019348 dolichol metabolic process 3.966368e-5
GO:0046038 GMP catabolic process 4.200645e-5
GO:0032264 IMP salvage 4.200645e-5
GO:0006178 guanine salvage 4.200645e-5
GO:0032263 GMP salvage 4.200645e-5
GO:0007067 mitosis 4.240779e-5
GO:0016569 covalent chromatin modification 4.285866e-5
GO:0019509 L-methionine salvage from methylthioadenosine 4.325420e-5
GO:0045922 negative regulation of fatty acid metabolic process 4.634270e-5
GO:0042254 ribosome biogenesis 4.872452e-5
GO:0007059 chromosome segregation 5.203707e-5
GO:0000087 M phase of mitotic cell cycle 5.244874e-5
GO:0010468 regulation of gene expression 5.917488e-5
GO:0006409 tRNA export from nucleus 6.628033e-5
GO:0019047 provirus integration 6.628033e-5
GO:2000112 regulation of cellular macromolecule biosynthetic process 7.003743e-5
GO:0034661 ncRNA catabolic process 7.127639e-5
GO:0010498 proteasomal protein catabolic process 7.767786e-5
GO:0035372 protein localization to microtubule 7.875091e-5
GO:0034619 cellular chaperone-mediated protein complex assembly 8.139301e-5
GO:0045454 cell redox homeostasis 8.370459e-5
GO:0016570 histone modification 8.941858e-5
GO:0006355 regulation of transcription, DNA-dependent 9.121836e-5
GO:0035507 regulation of myosin-light-chain-phosphatase activity 1.052976e-4
GO:0051443 positive regulation of ubiquitin-protein ligase activity 1.087433e-4
GO:0042473 outer ear morphogenesis 1.095068e-4
GO:0070925 organelle assembly 1.103040e-4
GO:0090083 regulation of inclusion body assembly 1.110703e-4
GO:0030866 cortical actin cytoskeleton organization 1.114438e-4
GO:0035269 protein O-linked mannosylation 1.129939e-4
GO:0032922 circadian regulation of gene expression 1.148771e-4
GO:0015876 acetyl-CoA transport 1.169599e-4
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 1.343047e-4
GO:0050775 positive regulation of dendrite morphogenesis 1.347902e-4
GO:0008612 peptidyl-lysine modification to hypusine 1.407588e-4
GO:0016926 protein desumoylation 1.407588e-4
GO:0034227 tRNA thio-modification 1.424047e-4
GO:0060319 primitive erythrocyte differentiation 1.496820e-4
GO:0071711 basement membrane organization 1.788634e-4
GO:0051225 spindle assembly 1.798864e-4
GO:0045717 negative regulation of fatty acid biosynthetic process 1.831597e-4
GO:0042733 embryonic digit morphogenesis 1.839459e-4
GO:0035441 cell migration involved in vasculogenesis 1.877542e-4
GO:0010987 negative regulation of high-density lipoprotein particle clearance 1.880940e-4
GO:0010897 negative regulation of triglyceride catabolic process 1.880940e-4
GO:0035195 gene silencing by miRNA 1.888056e-4
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.930350e-4
GO:0006344 maintenance of chromatin silencing 2.086191e-4
GO:0018243 protein O-linked glycosylation via threonine 2.087524e-4
GO:0018242 protein O-linked glycosylation via serine 2.087524e-4
GO:0018065 protein-cofactor linkage 2.087524e-4
GO:0060534 trachea cartilage development 2.170776e-4
GO:0009113 purine base biosynthetic process 2.233500e-4
GO:0090234 regulation of kinetochore assembly 2.468013e-4
GO:0000395 nuclear mRNA 5'-splice site recognition 2.468013e-4
GO:0090169 regulation of spindle assembly 2.468013e-4
GO:0030968 endoplasmic reticulum unfolded protein response 2.523312e-4
GO:2000380 regulation of mesoderm development 2.544855e-4
GO:0033119 negative regulation of RNA splicing 2.544855e-4
GO:0016574 histone ubiquitination 2.556831e-4
GO:0035520 monoubiquitinated protein deubiquitination 2.606149e-4
GO:2000688 positive regulation of rubidium ion transmembrane transporter activity 2.620371e-4
GO:0035826 rubidium ion transport 2.620371e-4
GO:2000682 positive regulation of rubidium ion transport 2.620371e-4
GO:0007126 meiosis 2.649634e-4
GO:0033239 negative regulation of cellular amine metabolic process 2.767076e-4
GO:0007140 male meiosis 2.904172e-4
GO:0071108 protein K48-linked deubiquitination 2.904810e-4
GO:0090231 regulation of spindle checkpoint 2.904810e-4
GO:0045022 early endosome to late endosome transport 2.994870e-4
GO:0042278 purine nucleoside metabolic process 3.057259e-4
GO:0006482 protein demethylation 3.060398e-4
GO:0051030 snRNA transport 3.189912e-4
GO:0061084 negative regulation of protein refolding 3.231385e-4
GO:0021903 rostrocaudal neural tube patterning 3.449515e-4
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 3.486036e-4
GO:0006448 regulation of translational elongation 3.506725e-4
GO:0070193 synaptonemal complex organization 3.585079e-4
GO:0072513 positive regulation of secondary heart field cardioblast proliferation 3.679456e-4
GO:0060535 trachea cartilage morphogenesis 3.711629e-4
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.792552e-4
GO:0070831 basement membrane assembly 3.792552e-4
GO:0042273 ribosomal large subunit biogenesis 3.887872e-4
GO:0015931 nucleobase-containing compound transport 4.124664e-4
GO:0051036 regulation of endosome size 4.128898e-4
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 4.128898e-4
GO:0031119 tRNA pseudouridine synthesis 4.128898e-4
GO:0071394 cellular response to testosterone stimulus 4.208603e-4
GO:0033084 regulation of immature T cell proliferation in thymus 4.253421e-4
GO:0038007 netrin-activated signaling pathway 4.254141e-4
GO:0034214 protein hexamerization 4.254141e-4
GO:0043148 mitotic spindle stabilization 4.309708e-4
GO:0018192 enzyme active site formation via L-cysteine persulfide 4.309708e-4
GO:0043484 regulation of RNA splicing 4.423271e-4
GO:0045901 positive regulation of translational elongation 4.469893e-4
GO:0045905 positive regulation of translational termination 4.469893e-4
GO:0006452 translational frameshifting 4.469893e-4
GO:0034641 cellular nitrogen compound metabolic process 4.494008e-4
GO:0070368 positive regulation of hepatocyte differentiation 4.537968e-4
GO:0021871 forebrain regionalization 4.913888e-4
GO:0072111 cell proliferation involved in kidney development 5.119269e-4
GO:0051583 dopamine uptake 5.134335e-4
GO:0007127 meiosis I 5.141864e-4
GO:0021696 cerebellar cortex morphogenesis 5.176219e-4
GO:0032006 regulation of TOR signaling cascade 5.430167e-4
GO:0007498 mesoderm development 5.485920e-4
GO:0044265 cellular macromolecule catabolic process 5.535878e-4
GO:0006342 chromatin silencing 5.628454e-4
GO:0006986 response to unfolded protein 5.669354e-4
GO:0010824 regulation of centrosome duplication 5.794937e-4
GO:0060136 embryonic process involved in female pregnancy 5.794937e-4
GO:0016180 snRNA processing 5.814722e-4
GO:0071843 cellular component biogenesis at cellular level 5.819550e-4
GO:0018023 peptidyl-lysine trimethylation 5.950713e-4
GO:0060236 regulation of mitotic spindle organization 5.950713e-4
GO:0000070 mitotic sister chromatid segregation 6.245002e-4
GO:0007288 sperm axoneme assembly 6.344557e-4
GO:0035967 cellular response to topologically incorrect protein 6.372212e-4
GO:0061034 olfactory bulb mitral cell layer development 6.730764e-4
GO:0051171 regulation of nitrogen compound metabolic process 6.764507e-4
GO:0051005 negative regulation of lipoprotein lipase activity 6.934264e-4
GO:0022613 ribonucleoprotein complex biogenesis 6.939509e-4
GO:0042996 regulation of Golgi to plasma membrane protein transport 6.966528e-4
GO:0060920 pacemaker cell differentiation 7.199213e-4
GO:0010870 positive regulation of receptor biosynthetic process 7.417795e-4
GO:0030917 midbrain-hindbrain boundary development 7.419997e-4
GO:0032784 regulation of transcription elongation, DNA-dependent 7.419997e-4
GO:0042026 protein refolding 7.538821e-4
GO:0018126 protein hydroxylation 7.710331e-4
GO:0045646 regulation of erythrocyte differentiation 7.776225e-4
GO:0051383 kinetochore organization 7.906065e-4
GO:0021532 neural tube patterning 8.168094e-4
GO:0009952 anterior/posterior pattern specification 8.592893e-4
GO:0045963 negative regulation of dopamine metabolic process 8.789216e-4
GO:0050668 positive regulation of homocysteine metabolic process 8.789216e-4
GO:0006346 methylation-dependent chromatin silencing 8.977211e-4
GO:0010985 negative regulation of lipoprotein particle clearance 8.981009e-4
GO:0000278 mitotic cell cycle 9.616477e-4
GO:0000819 sister chromatid segregation 9.701114e-4
GO:0019219 regulation of nucleobase-containing compound metabolic process 9.778017e-4
GO:0021516 dorsal spinal cord development 9.810696e-4
GO:0016577 histone demethylation 9.981878e-4
GO:0002268 follicular dendritic cell differentiation 1.003551e-3
GO:0000731 DNA synthesis involved in DNA repair 1.003551e-3
GO:0051103 DNA ligation involved in DNA repair 1.011076e-3
GO:0048291 isotype switching to IgG isotypes 1.035929e-3
GO:0046452 dihydrofolate metabolic process 1.035929e-3
GO:0071105 response to interleukin-11 1.035929e-3
GO:0002368 B cell cytokine production 1.035929e-3
GO:0030150 protein import into mitochondrial matrix 1.035929e-3
GO:0006189 'de novo' IMP biosynthetic process 1.047384e-3
GO:0060764 cell-cell signaling involved in mammary gland development 1.084784e-3
GO:0060948 cardiac vascular smooth muscle cell development 1.096259e-3
GO:0019673 GDP-mannose metabolic process 1.096259e-3
GO:0048255 mRNA stabilization 1.219091e-3
GO:0010556 regulation of macromolecule biosynthetic process 1.242937e-3
GO:0007141 male meiosis I 1.290176e-3
GO:0033083 regulation of immature T cell proliferation 1.321862e-3
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.325286e-3
GO:0003002 regionalization 1.333687e-3
GO:0010982 regulation of high-density lipoprotein particle clearance 1.359102e-3
GO:0048332 mesoderm morphogenesis 1.378601e-3
GO:0007052 mitotic spindle organization 1.416027e-3
GO:0006099 tricarboxylic acid cycle 1.422853e-3
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.448645e-3
GO:0044314 protein K27-linked ubiquitination 1.448645e-3
GO:0021527 spinal cord association neuron differentiation 1.459203e-3
GO:0009116 nucleoside metabolic process 1.486695e-3
GO:0018394 peptidyl-lysine acetylation 1.617686e-3
GO:0055118 negative regulation of cardiac muscle contraction 1.620817e-3
GO:0021884 forebrain neuron development 1.627802e-3
GO:0071174 mitotic cell cycle spindle checkpoint 1.675466e-3
GO:0051301 cell division 1.709686e-3
GO:0010452 histone H3-K36 methylation 1.759748e-3
GO:0046580 negative regulation of Ras protein signal transduction 1.765305e-3
GO:0071173 spindle assembly checkpoint 1.765859e-3
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1.809710e-3
GO:0048295 positive regulation of isotype switching to IgE isotypes 1.812139e-3
GO:0001672 regulation of chromatin assembly or disassembly 1.842714e-3
GO:0048382 mesendoderm development 1.882750e-3
GO:0021930 cerebellar granule cell precursor proliferation 1.882750e-3
GO:0046881 positive regulation of follicle-stimulating hormone secretion 1.882750e-3
GO:0051351 positive regulation of ligase activity 1.927681e-3
GO:0072110 glomerular mesangial cell proliferation 1.979791e-3
GO:0016073 snRNA metabolic process 1.995194e-3
GO:0070286 axonemal dynein complex assembly 2.025108e-3
GO:0033088 negative regulation of immature T cell proliferation in thymus 2.025108e-3
GO:0033238 regulation of cellular amine metabolic process 2.138903e-3
GO:0060033 anatomical structure regression 2.141660e-3
GO:0046356 acetyl-CoA catabolic process 2.158056e-3
GO:0021587 cerebellum morphogenesis 2.176525e-3
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 2.179320e-3
GO:0032465 regulation of cytokinesis 2.224559e-3
GO:0060921 sinoatrial node cell differentiation 2.292299e-3
GO:0032007 negative regulation of TOR signaling cascade 2.326317e-3
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 2.347603e-3
GO:0071267 L-methionine salvage 2.347603e-3
GO:0010799 regulation of peptidyl-threonine phosphorylation 2.369476e-3
GO:0030219 megakaryocyte differentiation 2.371001e-3
GO:0090342 regulation of cell aging 2.380029e-3
GO:0060438 trachea development 2.471230e-3
GO:0018393 internal peptidyl-lysine acetylation 2.601122e-3
GO:0060977 coronary vasculature morphogenesis 2.634146e-3
GO:0021520 spinal cord motor neuron cell fate specification 2.636434e-3
GO:0006414 translational elongation 2.653030e-3
GO:0001880 Mullerian duct regression 2.680584e-3
GO:0043173 nucleotide salvage 2.759025e-3
GO:0016573 histone acetylation 2.797234e-3
GO:0040029 regulation of gene expression, epigenetic 2.814587e-3
GO:0010989 negative regulation of low-density lipoprotein particle clearance 2.822908e-3
GO:0051131 chaperone-mediated protein complex assembly 2.822908e-3
GO:0007264 small GTPase mediated signal transduction 2.913999e-3
GO:0010388 cullin deneddylation 2.931675e-3
GO:0021819 layer formation in cerebral cortex 3.010333e-3
GO:2000016 negative regulation of determination of dorsal identity 3.015843e-3
GO:0006408 snRNA export from nucleus 3.015843e-3
GO:0045292 nuclear mRNA cis splicing, via spliceosome 3.062355e-3
GO:0007094 mitotic cell cycle spindle assembly checkpoint 3.062355e-3
GO:0045750 positive regulation of S phase of mitotic cell cycle 3.090895e-3
GO:0035404 histone-serine phosphorylation 3.099644e-3
GO:2000651 positive regulation of sodium ion transmembrane transporter activity 3.110220e-3
GO:0010984 regulation of lipoprotein particle clearance 3.134600e-3
GO:0042417 dopamine metabolic process 3.166720e-3
GO:0035562 negative regulation of chromatin binding 3.405691e-3
GO:0021953 central nervous system neuron differentiation 3.522033e-3
GO:0033127 regulation of histone phosphorylation 3.633443e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 3.639210e-3
GO:0014812 muscle cell migration 3.690288e-3
GO:0034587 piRNA metabolic process 3.736295e-3
GO:0030719 P granule organization 3.765988e-3
GO:0060461 right lung morphogenesis 3.769956e-3
GO:0090131 mesenchyme migration 3.769956e-3
GO:0070194 synaptonemal complex disassembly 3.769956e-3
GO:0048613 embryonic ectodermal digestive tract morphogenesis 3.769956e-3
GO:0014822 detection of wounding 3.769956e-3
GO:0048371 lateral mesodermal cell differentiation 3.769956e-3
GO:0060446 branching involved in open tracheal system development 3.769956e-3
GO:0048642 negative regulation of skeletal muscle tissue development 3.799118e-3
GO:0070918 production of small RNA involved in gene silencing by RNA 3.800031e-3
GO:0060375 regulation of mast cell differentiation 3.813284e-3
GO:0031577 spindle checkpoint 3.827053e-3
GO:0060482 lobar bronchus development 3.945750e-3
GO:0032467 positive regulation of cytokinesis 3.983272e-3
GO:0021697 cerebellar cortex formation 4.008699e-3
GO:0060318 definitive erythrocyte differentiation 4.041714e-3
GO:0006999 nuclear pore organization 4.041714e-3
GO:0009953 dorsal/ventral pattern formation 4.082737e-3
GO:0017187 peptidyl-glutamic acid carboxylation 4.095304e-3
GO:0006683 galactosylceramide catabolic process 4.095304e-3
GO:0051865 protein autoubiquitination 4.123866e-3
GO:0071506 cellular response to mycophenolic acid 4.244216e-3
GO:0072126 positive regulation of glomerular mesangial cell proliferation 4.244216e-3
GO:0046498 S-adenosylhomocysteine metabolic process 4.282162e-3
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 4.323706e-3
GO:0006168 adenine salvage 4.350139e-3
GO:0006545 glycine biosynthetic process 4.350139e-3
GO:2000256 positive regulation of male germ cell proliferation 4.507643e-3
GO:0072355 histone H3-T3 phosphorylation 4.507643e-3
GO:0000963 mitochondrial RNA processing 4.507643e-3
GO:0042231 interleukin-13 biosynthetic process 4.507643e-3
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 4.568457e-3
GO:0097107 postsynaptic density assembly 4.568457e-3
GO:0021915 neural tube development 4.682113e-3
GO:0021680 cerebellar Purkinje cell layer development 4.823794e-3
GO:0032532 regulation of microvillus length 4.905388e-3
GO:0046370 fructose biosynthetic process 4.905388e-3
GO:0033274 response to vitamin B2 4.905388e-3
GO:0065002 intracellular protein transmembrane transport 4.905388e-3
GO:0060975 cardioblast migration to the midline involved in heart field formation 4.905388e-3
GO:0051160 L-xylitol catabolic process 4.905388e-3
GO:0046604 positive regulation of mitotic centrosome separation 4.905388e-3
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 4.905388e-3
GO:0003236 sinus venosus morphogenesis 4.905388e-3
GO:0003210 cardiac atrium formation 4.905388e-3
GO:0001682 tRNA 5'-leader removal 4.905388e-3
GO:0003259 cardioblast anterior-lateral migration 4.905388e-3
GO:0006062 sorbitol catabolic process 4.905388e-3
GO:0016078 tRNA catabolic process 4.905388e-3
GO:0009159 deoxyribonucleoside monophosphate catabolic process 4.905388e-3
GO:0021528 commissural neuron differentiation in spinal cord 4.905388e-3
GO:0051058 negative regulation of small GTPase mediated signal transduction 4.918659e-3
GO:0002069 columnar/cuboidal epithelial cell maturation 5.151511e-3
GO:0003221 right ventricular cardiac muscle tissue morphogenesis 5.151511e-3
GO:0042661 regulation of mesodermal cell fate specification 5.225649e-3
GO:0034382 chylomicron remnant clearance 5.252859e-3
GO:0001841 neural tube formation 5.421178e-3
GO:0060591 chondroblast differentiation 5.465138e-3
GO:0006415 translational termination 5.465138e-3
GO:0016082 synaptic vesicle priming 5.465138e-3
GO:0060684 epithelial-mesenchymal cell signaling 5.507077e-3
GO:0051438 regulation of ubiquitin-protein ligase activity 5.609963e-3
GO:0009057 macromolecule catabolic process 5.613465e-3
GO:0070979 protein K11-linked ubiquitination 5.655599e-3
GO:0033523 histone H2B ubiquitination 5.915360e-3
GO:0045875 negative regulation of sister chromatid cohesion 5.935485e-3
GO:0035461 vitamin transmembrane transport 5.935485e-3
GO:0072203 cell proliferation involved in metanephros development 5.993076e-3
GO:0031129 inductive cell-cell signaling 6.105537e-3
GO:0045175 basal protein localization 6.105537e-3
GO:0018095 protein polyglutamylation 6.105537e-3
GO:0007023 post-chaperonin tubulin folding pathway 6.105537e-3
GO:0015937 coenzyme A biosynthetic process 6.313761e-3
GO:0006177 GMP biosynthetic process 6.315383e-3
GO:0000209 protein polyubiquitination 6.421284e-3
GO:0060896 neural plate pattern specification 6.521093e-3
GO:0048378 regulation of lateral mesodermal cell fate specification 6.700960e-3
GO:0033299 secretion of lysosomal enzymes 6.700960e-3
GO:0046128 purine ribonucleoside metabolic process 6.934822e-3
GO:0015936 coenzyme A metabolic process 6.954286e-3
GO:0021575 hindbrain morphogenesis 6.975088e-3
GO:0007352 zygotic specification of dorsal/ventral axis 6.976858e-3
GO:0021506 anterior neuropore closure 6.999354e-3
GO:0031647 regulation of protein stability 7.015922e-3
GO:0019532 oxalate transport 7.064266e-3
GO:0043153 entrainment of circadian clock by photoperiod 7.064266e-3
GO:0043301 negative regulation of leukocyte degranulation 7.070428e-3
GO:0033962 cytoplasmic mRNA processing body assembly 7.222436e-3
GO:0045908 negative regulation of vasodilation 7.262504e-3
GO:0060433 bronchus development 7.279642e-3
GO:0048102 autophagic cell death 7.300153e-3
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 7.300153e-3
GO:0048714 positive regulation of oligodendrocyte differentiation 7.405979e-3
GO:0015986 ATP synthesis coupled proton transport 7.472213e-3
GO:0045814 negative regulation of gene expression, epigenetic 7.492822e-3
GO:0001975 response to amphetamine 7.601555e-3
GO:0006473 protein acetylation 7.625281e-3
GO:0021702 cerebellar Purkinje cell differentiation 7.792642e-3
GO:2000381 negative regulation of mesoderm development 7.955419e-3
GO:0071872 cellular response to epinephrine stimulus 7.955419e-3
GO:0060574 intestinal epithelial cell maturation 8.105339e-3
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 8.105339e-3
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 8.105339e-3
GO:0006235 dTTP biosynthetic process 8.105339e-3
GO:0016068 type I hypersensitivity 8.105339e-3
GO:0033566 gamma-tubulin complex localization 8.105339e-3
GO:0009109 coenzyme catabolic process 8.211827e-3
GO:0006809 nitric oxide biosynthetic process 8.320133e-3
GO:0035196 production of miRNAs involved in gene silencing by miRNA 8.376793e-3
GO:0006412 translation 8.543977e-3
GO:0071354 cellular response to interleukin-6 8.546020e-3
GO:0060458 right lung development 8.631016e-3
GO:0021562 vestibulocochlear nerve development 8.631016e-3
GO:0006513 protein monoubiquitination 8.826250e-3
GO:0072199 regulation of mesenchymal cell proliferation involved in ureter development 8.970220e-3
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 9.119901e-3
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 9.119901e-3
GO:0016572 histone phosphorylation 9.142549e-3
GO:0060439 trachea morphogenesis 9.165627e-3
GO:0060932 His-Purkinje system cell differentiation 9.197437e-3
GO:0000959 mitochondrial RNA metabolic process 9.197437e-3
GO:0060926 pacemaker cell development 9.197437e-3
GO:0072075 metanephric mesenchyme development 9.212408e-3
GO:0031497 chromatin assembly 9.325622e-3
GO:0021603 cranial nerve formation 9.563829e-3
GO:0070935 3'-UTR-mediated mRNA stabilization 9.715331e-3
GO:0090086 negative regulation of protein deubiquitination 9.715331e-3
GO:0055119 relaxation of cardiac muscle 9.744535e-3
GO:0018193 peptidyl-amino acid modification 9.824550e-3
GO:0072074 kidney mesenchyme development 1.006924e-2
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.022489e-2
GO:0060216 definitive hemopoiesis 1.057831e-2
GO:0060084 synaptic transmission involved in micturition 1.062564e-2
GO:0042851 L-alanine metabolic process 1.062564e-2
GO:0051315 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 1.062564e-2
GO:0009948 anterior/posterior axis specification 1.080926e-2
GO:0009648 photoperiodism 1.093521e-2
GO:0009299 mRNA transcription 1.093521e-2
GO:0030433 ER-associated protein catabolic process 1.105007e-2
GO:0048352 paraxial mesoderm structural organization 1.110661e-2
GO:0042789 mRNA transcription from RNA polymerase II promoter 1.110661e-2
GO:0016191 synaptic vesicle uncoating 1.110661e-2
GO:0021998 neural plate mediolateral regionalization 1.110661e-2
GO:0006413 translational initiation 1.118416e-2
GO:0032008 positive regulation of TOR signaling cascade 1.134413e-2
GO:0072189 ureter development 1.138668e-2
GO:0042255 ribosome assembly 1.143307e-2
GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 1.173060e-2
GO:0006475 internal protein amino acid acetylation 1.174388e-2
GO:0006975 DNA damage induced protein phosphorylation 1.182259e-2
GO:0000578 embryonic axis specification 1.186540e-2
GO:0035176 social behavior 1.192605e-2
GO:0006281 DNA repair 1.237674e-2
GO:0071476 cellular hypotonic response 1.243291e-2
GO:0032926 negative regulation of activin receptor signaling pathway 1.243291e-2
GO:0021895 cerebral cortex neuron differentiation 1.248634e-2
GO:0046847 filopodium assembly 1.252334e-2
GO:0046782 regulation of viral transcription 1.266492e-2
GO:0031055 chromatin remodeling at centromere 1.281728e-2
GO:0046599 regulation of centriole replication 1.287221e-2
GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development 1.301971e-2
GO:0045630 positive regulation of T-helper 2 cell differentiation 1.301971e-2
GO:0043457 regulation of cellular respiration 1.301971e-2
GO:0000212 meiotic spindle organization 1.301971e-2
GO:0071901 negative regulation of protein serine/threonine kinase activity 1.305908e-2
GO:0050434 positive regulation of viral transcription 1.308350e-2
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 1.340723e-2
GO:0071422 succinate transmembrane transport 1.340723e-2
GO:0046836 glycolipid transport 1.340723e-2
GO:0006601 creatine biosynthetic process 1.340723e-2
GO:0001963 synaptic transmission, dopaminergic 1.341581e-2
GO:0032383 regulation of intracellular cholesterol transport 1.357741e-2
GO:0009236 cobalamin biosynthetic process 1.357741e-2
GO:0031468 nuclear envelope reassembly 1.357741e-2
GO:0015878 biotin transport 1.357741e-2
GO:0015887 pantothenate transmembrane transport 1.357741e-2
GO:0006807 nitrogen compound metabolic process 1.367493e-2
GO:0070170 regulation of tooth mineralization 1.371231e-2
GO:0016331 morphogenesis of embryonic epithelium 1.399326e-2
GO:0006333 chromatin assembly or disassembly 1.407556e-2
GO:0010891 negative regulation of sequestering of triglyceride 1.411476e-2