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Novel motif:156

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name:motif156_ACTGTAGGACMT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0009589 detection of UV 1.050573e-16
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 1.050573e-16
GO:0051932 synaptic transmission, GABAergic 3.386067e-16
GO:0070541 response to platinum ion 4.708101e-11
GO:0046501 protoporphyrinogen IX metabolic process 2.081235e-10
GO:0021771 lateral geniculate nucleus development 1.398719e-9
GO:0048513 organ development 2.837532e-9
GO:0048769 sarcomerogenesis 2.274643e-8
GO:0006941 striated muscle contraction 2.533357e-8
GO:0055013 cardiac muscle cell development 4.400299e-8
GO:0034436 glycoprotein transport 6.841598e-8
GO:0009720 detection of hormone stimulus 6.841598e-8
GO:0050878 regulation of body fluid levels 9.125473e-8
GO:0009726 detection of endogenous stimulus 9.672974e-8
GO:0030241 skeletal muscle myosin thick filament assembly 1.612854e-7
GO:0001906 cell killing 1.829453e-7
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 1.899696e-7
GO:0048731 system development 2.058605e-7
GO:0042060 wound healing 2.111094e-7
GO:0006527 arginine catabolic process 2.433631e-7
GO:0007076 mitotic chromosome condensation 2.915502e-7
GO:0031284 positive regulation of guanylate cyclase activity 4.605275e-7
GO:0007599 hemostasis 4.824092e-7
GO:0030240 skeletal muscle thin filament assembly 5.287503e-7
GO:0019046 reactivation of latent virus 5.584346e-7
GO:0007596 blood coagulation 5.763845e-7
GO:0048739 cardiac muscle fiber development 6.163500e-7
GO:0051897 positive regulation of protein kinase B signaling cascade 7.164313e-7
GO:0010288 response to lead ion 7.338574e-7
GO:0038007 netrin-activated signaling pathway 9.394558e-7
GO:0032501 multicellular organismal process 1.008131e-6
GO:0046541 saliva secretion 1.017217e-6
GO:0031444 slow-twitch skeletal muscle fiber contraction 1.017217e-6
GO:0051896 regulation of protein kinase B signaling cascade 1.050193e-6
GO:0060084 synaptic transmission involved in micturition 1.216706e-6
GO:0006783 heme biosynthetic process 1.294486e-6
GO:0031640 killing of cells of other organism 1.319876e-6
GO:0051146 striated muscle cell differentiation 1.466638e-6
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 1.799052e-6
GO:0070838 divalent metal ion transport 1.832981e-6
GO:0030048 actin filament-based movement 2.029646e-6
GO:0019538 protein metabolic process 2.069434e-6
GO:0006816 calcium ion transport 2.150080e-6
GO:0072511 divalent inorganic cation transport 2.175094e-6
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 2.324040e-6
GO:0006525 arginine metabolic process 2.766498e-6
GO:0002576 platelet degranulation 2.799405e-6
GO:0042692 muscle cell differentiation 2.920792e-6
GO:0030168 platelet activation 2.938829e-6
GO:0033577 protein glycosylation in endoplasmic reticulum 3.416194e-6
GO:0048840 otolith development 3.426996e-6
GO:0006950 response to stress 3.447854e-6
GO:0070588 calcium ion transmembrane transport 3.933621e-6
GO:0014866 skeletal myofibril assembly 4.004331e-6
GO:0007275 multicellular organismal development 4.042492e-6
GO:0010038 response to metal ion 4.400170e-6
GO:0070482 response to oxygen levels 4.734354e-6
GO:0007520 myoblast fusion 5.004333e-6
GO:0018149 peptide cross-linking 5.597816e-6
GO:0055003 cardiac myofibril assembly 5.955901e-6
GO:0031282 regulation of guanylate cyclase activity 6.214021e-6
GO:0001974 blood vessel remodeling 6.605821e-6
GO:0055099 response to high density lipoprotein particle stimulus 6.607728e-6
GO:0001666 response to hypoxia 6.713829e-6
GO:0030187 melatonin biosynthetic process 7.951023e-6
GO:0042026 protein refolding 9.397521e-6
GO:0032502 developmental process 9.509061e-6
GO:2000304 positive regulation of ceramide biosynthetic process 9.885103e-6
GO:0055094 response to lipoprotein stimulus 1.115139e-5
GO:0000070 mitotic sister chromatid segregation 1.134175e-5
GO:0051597 response to methylmercury 1.182144e-5
GO:0043537 negative regulation of blood vessel endothelial cell migration 1.298462e-5
GO:2000303 regulation of ceramide biosynthetic process 1.514058e-5
GO:0006508 proteolysis 1.620127e-5
GO:0001542 ovulation from ovarian follicle 1.646005e-5
GO:0070104 negative regulation of interleukin-6-mediated signaling pathway 1.675516e-5
GO:0000819 sister chromatid segregation 1.760991e-5
GO:0097006 regulation of plasma lipoprotein particle levels 1.898505e-5
GO:0030278 regulation of ossification 1.966583e-5
GO:0030001 metal ion transport 1.966761e-5
GO:0045759 negative regulation of action potential 2.008727e-5
GO:0006936 muscle contraction 2.382699e-5
GO:0043316 cytotoxic T cell degranulation 2.540090e-5
GO:0044087 regulation of cellular component biogenesis 2.551997e-5
GO:0018160 peptidyl-pyrromethane cofactor linkage 2.696997e-5
GO:0019220 regulation of phosphate metabolic process 2.748702e-5
GO:0030049 muscle filament sliding 2.755895e-5
GO:0006949 syncytium formation 2.772711e-5
GO:0032147 activation of protein kinase activity 2.945148e-5
GO:0010885 regulation of cholesterol storage 2.987307e-5
GO:0032268 regulation of cellular protein metabolic process 3.095446e-5
GO:0042325 regulation of phosphorylation 3.116322e-5
GO:2000753 positive regulation of glucosylceramide catabolic process 3.151758e-5
GO:2000755 positive regulation of sphingomyelin catabolic process 3.151758e-5
GO:0070106 interleukin-27-mediated signaling pathway 3.236077e-5
GO:0048856 anatomical structure development 3.284628e-5
GO:0003012 muscle system process 3.344449e-5
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 3.370265e-5
GO:0032226 positive regulation of synaptic transmission, dopaminergic 3.400175e-5
GO:0045214 sarcomere organization 3.460833e-5
GO:0071103 DNA conformation change 3.480290e-5
GO:0070252 actin-mediated cell contraction 3.650559e-5
GO:0009887 organ morphogenesis 3.675923e-5
GO:0021562 vestibulocochlear nerve development 3.842863e-5
GO:0000279 M phase 4.041966e-5
GO:0010751 negative regulation of nitric oxide mediated signal transduction 4.213954e-5
GO:0043652 engulfment of apoptotic cell 4.213954e-5
GO:0010754 negative regulation of cGMP-mediated signaling 4.213954e-5
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 4.213954e-5
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 4.213954e-5
GO:0014902 myotube differentiation 4.445818e-5
GO:0006779 porphyrin-containing compound biosynthetic process 4.466165e-5
GO:0010883 regulation of lipid storage 4.677258e-5
GO:0048075 positive regulation of eye pigmentation 4.688825e-5
GO:0055007 cardiac muscle cell differentiation 4.771142e-5
GO:0042168 heme metabolic process 4.893512e-5
GO:0050673 epithelial cell proliferation 4.941711e-5
GO:0043353 enucleate erythrocyte differentiation 4.951652e-5
GO:0032891 negative regulation of organic acid transport 5.083355e-5
GO:0035914 skeletal muscle cell differentiation 5.201578e-5
GO:0009611 response to wounding 5.341072e-5
GO:0045766 positive regulation of angiogenesis 5.479333e-5
GO:0014706 striated muscle tissue development 5.566827e-5
GO:0000173 inactivation of MAPK activity involved in osmosensory signaling pathway 6.076096e-5
GO:0042053 regulation of dopamine metabolic process 6.298936e-5
GO:0032298 positive regulation of DNA-dependent DNA replication initiation 6.383551e-5
GO:0050928 negative regulation of positive chemotaxis 6.711415e-5
GO:0045542 positive regulation of cholesterol biosynthetic process 6.717886e-5
GO:0071803 positive regulation of podosome assembly 6.765107e-5
GO:0002544 chronic inflammatory response 6.830139e-5
GO:0031399 regulation of protein modification process 6.884798e-5
GO:0030154 cell differentiation 7.235863e-5
GO:0048747 muscle fiber development 7.270850e-5
GO:0006778 porphyrin-containing compound metabolic process 7.328880e-5
GO:0071549 cellular response to dexamethasone stimulus 7.429546e-5
GO:0042069 regulation of catecholamine metabolic process 7.429546e-5
GO:0007059 chromosome segregation 7.466702e-5
GO:0000045 autophagic vacuole assembly 7.602640e-5
GO:0002088 lens development in camera-type eye 7.757471e-5
GO:0002577 regulation of antigen processing and presentation 7.876840e-5
GO:2000377 regulation of reactive oxygen species metabolic process 7.887148e-5
GO:0048869 cellular developmental process 7.973306e-5
GO:0001963 synaptic transmission, dopaminergic 8.058401e-5
GO:0010035 response to inorganic substance 8.086459e-5
GO:0045187 regulation of circadian sleep/wake cycle, sleep 8.903211e-5
GO:0065008 regulation of biological quality 9.358452e-5
GO:0055008 cardiac muscle tissue morphogenesis 9.400611e-5
GO:0007256 activation of JNKK activity 9.483951e-5
GO:0015671 oxygen transport 1.020709e-4
GO:0048073 regulation of eye pigmentation 1.084229e-4
GO:0022410 circadian sleep/wake cycle process 1.101112e-4
GO:0030838 positive regulation of actin filament polymerization 1.160430e-4
GO:0009065 glutamine family amino acid catabolic process 1.168628e-4
GO:0033013 tetrapyrrole metabolic process 1.170641e-4
GO:0045577 regulation of B cell differentiation 1.185015e-4
GO:0010888 negative regulation of lipid storage 1.197485e-4
GO:0009653 anatomical structure morphogenesis 1.255013e-4
GO:0061048 negative regulation of branching involved in lung morphogenesis 1.255653e-4
GO:0045834 positive regulation of lipid metabolic process 1.287898e-4
GO:0042745 circadian sleep/wake cycle 1.353026e-4
GO:0060537 muscle tissue development 1.398339e-4
GO:0009636 response to toxin 1.410318e-4
GO:0007214 gamma-aminobutyric acid signaling pathway 1.426926e-4
GO:0007270 neuron-neuron synaptic transmission 1.481127e-4
GO:0090205 positive regulation of cholesterol metabolic process 1.610398e-4
GO:0034231 islet amyloid polypeptide processing 1.637466e-4
GO:0034230 enkephalin processing 1.637466e-4
GO:0006812 cation transport 1.690260e-4
GO:0001932 regulation of protein phosphorylation 1.722959e-4
GO:0007231 osmosensory signaling pathway 1.746473e-4
GO:0042752 regulation of circadian rhythm 1.785033e-4
GO:0050680 negative regulation of epithelial cell proliferation 1.822306e-4
GO:0000087 M phase of mitotic cell cycle 1.832345e-4
GO:0048512 circadian behavior 1.847344e-4
GO:0021631 optic nerve morphogenesis 1.885999e-4
GO:0050867 positive regulation of cell activation 1.898467e-4
GO:0035051 cardiac cell differentiation 1.971904e-4
GO:0071827 plasma lipoprotein particle organization 1.977166e-4
GO:0070103 regulation of interleukin-6-mediated signaling pathway 2.004961e-4
GO:0000186 activation of MAPKK activity 2.048589e-4
GO:0030218 erythrocyte differentiation 2.069664e-4
GO:0009888 tissue development 2.128337e-4
GO:0034379 very-low-density lipoprotein particle assembly 2.139053e-4
GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 2.141329e-4
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway 2.374093e-4
GO:2000612 regulation of thyroid-stimulating hormone secretion 2.422010e-4
GO:0014740 negative regulation of muscle hyperplasia 2.422010e-4
GO:0014806 smooth muscle hyperplasia 2.422010e-4
GO:0010893 positive regulation of steroid biosynthetic process 2.426387e-4
GO:0055091 phospholipid homeostasis 2.429461e-4
GO:0008344 adult locomotory behavior 2.454559e-4
GO:0006323 DNA packaging 2.514109e-4
GO:0070102 interleukin-6-mediated signaling pathway 2.588843e-4
GO:0030186 melatonin metabolic process 2.618218e-4
GO:0070904 transepithelial L-ascorbic acid transport 2.826255e-4
GO:0042982 amyloid precursor protein metabolic process 2.954833e-4
GO:0051246 regulation of protein metabolic process 2.979419e-4
GO:0045667 regulation of osteoblast differentiation 3.002766e-4
GO:0007626 locomotory behavior 3.153611e-4
GO:0046889 positive regulation of lipid biosynthetic process 3.195992e-4
GO:0032368 regulation of lipid transport 3.234719e-4
GO:0043949 regulation of cAMP-mediated signaling 3.287078e-4
GO:0002344 B cell affinity maturation 3.316961e-4
GO:0010743 regulation of macrophage derived foam cell differentiation 3.321448e-4
GO:0050881 musculoskeletal movement 3.362601e-4
GO:0007067 mitosis 3.472671e-4
GO:0048568 embryonic organ development 3.530814e-4
GO:0060415 muscle tissue morphogenesis 3.617653e-4
GO:0030261 chromosome condensation 3.695806e-4
GO:0032914 positive regulation of transforming growth factor beta1 production 3.837460e-4
GO:0021554 optic nerve development 3.947959e-4
GO:0072278 metanephric comma-shaped body morphogenesis 4.060380e-4
GO:0007525 somatic muscle development 4.080222e-4
GO:0042312 regulation of vasodilation 4.169504e-4
GO:0055001 muscle cell development 4.176472e-4
GO:0051533 positive regulation of NFAT protein import into nucleus 4.205969e-4
GO:0010887 negative regulation of cholesterol storage 4.226364e-4
GO:0007622 rhythmic behavior 4.231924e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 4.238872e-4
GO:0070076 histone lysine demethylation 4.335677e-4
GO:0051895 negative regulation of focal adhesion assembly 4.335677e-4
GO:0014738 regulation of muscle hyperplasia 4.349392e-4
GO:0032613 interleukin-10 production 4.652388e-4
GO:0030970 retrograde protein transport, ER to cytosol 4.653632e-4
GO:0007423 sensory organ development 4.941699e-4
GO:0006887 exocytosis 5.073110e-4
GO:0006746 FADH2 metabolic process 5.077216e-4
GO:0051414 response to cortisol stimulus 5.141290e-4
GO:0000165 MAPKKK cascade 5.163939e-4
GO:0048285 organelle fission 5.223473e-4
GO:0032890 regulation of organic acid transport 5.325876e-4
GO:0050818 regulation of coagulation 5.400914e-4
GO:0042320 regulation of circadian sleep/wake cycle, REM sleep 5.662871e-4
GO:0014745 negative regulation of muscle adaptation 5.662871e-4
GO:0071548 response to dexamethasone stimulus 5.806125e-4
GO:0010763 positive regulation of fibroblast migration 5.890274e-4
GO:0051481 reduction of cytosolic calcium ion concentration 5.899759e-4
GO:0048729 tissue morphogenesis 6.020251e-4
GO:0043587 tongue morphogenesis 6.114943e-4
GO:0010757 negative regulation of plasminogen activation 6.166275e-4
GO:0030070 insulin processing 6.193375e-4
GO:0048671 negative regulation of collateral sprouting 6.487990e-4
GO:0043267 negative regulation of potassium ion transport 6.487990e-4
GO:0001649 osteoblast differentiation 6.598985e-4
GO:0015669 gas transport 6.655465e-4
GO:0002339 B cell selection 6.871397e-4
GO:0051592 response to calcium ion 6.901441e-4
GO:0050896 response to stimulus 6.953235e-4
GO:0010596 negative regulation of endothelial cell migration 6.967829e-4
GO:0045859 regulation of protein kinase activity 7.029622e-4
GO:0051918 negative regulation of fibrinolysis 7.142616e-4
GO:0007517 muscle organ development 7.283726e-4
GO:0007271 synaptic transmission, cholinergic 7.436207e-4
GO:0048644 muscle organ morphogenesis 7.440081e-4
GO:0043549 regulation of kinase activity 7.639186e-4
GO:0034101 erythrocyte homeostasis 7.665098e-4
GO:0060766 negative regulation of androgen receptor signaling pathway 7.877117e-4
GO:0030866 cortical actin cytoskeleton organization 7.923784e-4
GO:0030204 chondroitin sulfate metabolic process 7.923784e-4
GO:0001507 acetylcholine catabolic process in synaptic cleft 8.028377e-4
GO:0051338 regulation of transferase activity 8.071484e-4
GO:0030826 regulation of cGMP biosynthetic process 8.157783e-4
GO:0061084 negative regulation of protein refolding 8.163554e-4
GO:0035095 behavioral response to nicotine 8.163554e-4
GO:0032695 negative regulation of interleukin-12 production 8.415746e-4
GO:0023021 termination of signal transduction 8.768742e-4
GO:0032367 intracellular cholesterol transport 8.781959e-4
GO:0010755 regulation of plasminogen activation 8.976891e-4
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 8.976891e-4
GO:0006891 intra-Golgi vesicle-mediated transport 9.437045e-4
GO:0060557 positive regulation of vitamin D biosynthetic process 9.514553e-4
GO:0022414 reproductive process 9.657818e-4
GO:0030865 cortical cytoskeleton organization 9.681043e-4
GO:0032402 melanosome transport 9.766771e-4
GO:0003009 skeletal muscle contraction 9.772890e-4
GO:0016236 macroautophagy 9.809999e-4
GO:0040008 regulation of growth 9.892876e-4
GO:0051917 regulation of fibrinolysis 1.019513e-3
GO:0015993 molecular hydrogen transport 1.023559e-3
GO:0008543 fibroblast growth factor receptor signaling pathway 1.025797e-3
GO:0070278 extracellular matrix constituent secretion 1.030385e-3
GO:0010260 organ senescence 1.030385e-3
GO:0060696 regulation of phospholipid catabolic process 1.030385e-3
GO:0033605 positive regulation of catecholamine secretion 1.039081e-3
GO:0045682 regulation of epidermis development 1.041067e-3
GO:0043535 regulation of blood vessel endothelial cell migration 1.072277e-3
GO:0046219 indolalkylamine biosynthetic process 1.080941e-3
GO:0048511 rhythmic process 1.086536e-3
GO:0002696 positive regulation of leukocyte activation 1.094235e-3
GO:0009582 detection of abiotic stimulus 1.111110e-3
GO:0044254 multicellular organismal protein catabolic process 1.113800e-3
GO:0000003 reproduction 1.125194e-3
GO:0010759 positive regulation of macrophage chemotaxis 1.177849e-3
GO:0030239 myofibril assembly 1.179364e-3
GO:0002089 lens morphogenesis in camera-type eye 1.190840e-3
GO:0032232 negative regulation of actin filament bundle assembly 1.222963e-3
GO:0072387 flavin adenine dinucleotide metabolic process 1.253731e-3
GO:0006642 triglyceride mobilization 1.253823e-3
GO:2000594 positive regulation of metanephric DCT cell differentiation 1.267415e-3
GO:0039003 pronephric field specification 1.267415e-3
GO:0072305 negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis 1.267415e-3
GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway 1.271603e-3
GO:0030832 regulation of actin filament length 1.272053e-3
GO:0030534 adult behavior 1.296612e-3
GO:0033603 positive regulation of dopamine secretion 1.298671e-3
GO:0060235 lens induction in camera-type eye 1.325022e-3
GO:0046685 response to arsenic-containing substance 1.383449e-3
GO:0010758 regulation of macrophage chemotaxis 1.383449e-3
GO:0017085 response to insecticide 1.383449e-3
GO:0002005 angiotensin catabolic process in blood 1.386610e-3
GO:0044268 multicellular organismal protein metabolic process 1.392295e-3
GO:0048861 leukemia inhibitory factor signaling pathway 1.405916e-3
GO:0009628 response to abiotic stimulus 1.448738e-3
GO:0006605 protein targeting 1.490366e-3
GO:0070318 positive regulation of G0 to G1 transition 1.494993e-3
GO:0071557 histone H3-K27 demethylation 1.494993e-3
GO:0048014 Tie receptor signaling pathway 1.494993e-3
GO:0035574 histone H4-K20 demethylation 1.494993e-3
GO:0022403 cell cycle phase 1.497730e-3
GO:0051904 pigment granule transport 1.507948e-3
GO:0071498 cellular response to fluid shear stress 1.579276e-3
GO:2001013 epithelial cell proliferation involve in renal tubule morphogenesis 1.579276e-3
GO:0032908 regulation of transforming growth factor beta1 production 1.586660e-3
GO:0046903 secretion 1.595742e-3
GO:0043320 natural killer cell degranulation 1.602847e-3
GO:0072003 kidney rudiment formation 1.629519e-3
GO:0021794 thalamus development 1.640526e-3
GO:0050654 chondroitin sulfate proteoglycan metabolic process 1.673907e-3
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 1.674773e-3
GO:0032026 response to magnesium ion 1.689992e-3
GO:0010872 regulation of cholesterol esterification 1.709967e-3
GO:0070316 regulation of G0 to G1 transition 1.715990e-3
GO:0033238 regulation of cellular amine metabolic process 1.721000e-3
GO:0009583 detection of light stimulus 1.736355e-3
GO:0043032 positive regulation of macrophage activation 1.765181e-3
GO:0007507 heart development 1.779307e-3
GO:0051346 negative regulation of hydrolase activity 1.782020e-3
GO:0072284 metanephric S-shaped body morphogenesis 1.793724e-3
GO:0019852 L-ascorbic acid metabolic process 1.793724e-3
GO:0071675 regulation of mononuclear cell migration 1.813635e-3
GO:0061061 muscle structure development 1.832060e-3
GO:0045764 positive regulation of cellular amino acid metabolic process 1.835127e-3
GO:0001775 cell activation 1.877102e-3
GO:0010927 cellular component assembly involved in morphogenesis 1.885777e-3
GO:0006911 phagocytosis, engulfment 1.904889e-3
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 1.918680e-3
GO:0007049 cell cycle 1.926199e-3
GO:0034405 response to fluid shear stress 1.955952e-3
GO:0031117 positive regulation of microtubule depolymerization 1.958674e-3
GO:0032237 activation of store-operated calcium channel activity 1.974243e-3
GO:0010976 positive regulation of neuron projection development 2.012408e-3
GO:0002604 regulation of dendritic cell antigen processing and presentation 2.028622e-3
GO:0006606 protein import into nucleus 2.035295e-3
GO:0072160 nephron tubule epithelial cell differentiation 2.046717e-3
GO:0033240 positive regulation of cellular amine metabolic process 2.051683e-3
GO:0010955 negative regulation of protein processing 2.060741e-3
GO:0007258 JUN phosphorylation 2.062299e-3
GO:0032615 interleukin-12 production 2.088477e-3
GO:0019233 sensory perception of pain 2.110489e-3
GO:0032273 positive regulation of protein polymerization 2.110489e-3
GO:0072221 metanephric distal convoluted tubule development 2.121183e-3
GO:0032401 establishment of melanosome localization 2.176584e-3
GO:0005999 xylulose biosynthetic process 2.183392e-3
GO:0045727 positive regulation of translation 2.204398e-3
GO:0050670 regulation of lymphocyte proliferation 2.213585e-3
GO:0007628 adult walking behavior 2.241686e-3
GO:0006548 histidine catabolic process 2.256910e-3
GO:0016043 cellular component organization 2.277693e-3
GO:0042987 amyloid precursor protein catabolic process 2.307271e-3
GO:0032800 receptor biosynthetic process 2.359069e-3
GO:0050865 regulation of cell activation 2.372540e-3
GO:0022402 cell cycle process 2.376644e-3
GO:2000191 regulation of fatty acid transport 2.410895e-3
GO:0048793 pronephros development 2.439639e-3
GO:0002456 T cell mediated immunity 2.443922e-3
GO:0006464 protein modification process 2.473788e-3
GO:0071622 regulation of granulocyte chemotaxis 2.476370e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 2.483560e-3
GO:0008629 induction of apoptosis by intracellular signals 2.566108e-3
GO:0033235 positive regulation of protein sumoylation 2.586713e-3
GO:0051170 nuclear import 2.591032e-3
GO:0061333 renal tubule morphogenesis 2.599991e-3
GO:0045940 positive regulation of steroid metabolic process 2.602701e-3
GO:0030301 cholesterol transport 2.624415e-3
GO:0090218 positive regulation of lipid kinase activity 2.678794e-3
GO:0048670 regulation of collateral sprouting 2.701088e-3
GO:0032944 regulation of mononuclear cell proliferation 2.744432e-3
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 2.752352e-3
GO:0051234 establishment of localization 2.833351e-3
GO:0071636 positive regulation of transforming growth factor beta production 2.863743e-3
GO:0045579 positive regulation of B cell differentiation 2.891438e-3
GO:0007274 neuromuscular synaptic transmission 2.917690e-3
GO:0044344 cellular response to fibroblast growth factor stimulus 2.930816e-3
GO:0001990 regulation of systemic arterial blood pressure by hormone 2.998738e-3
GO:0071354 cellular response to interleukin-6 3.042042e-3
GO:0006810 transport 3.048794e-3
GO:0051347 positive regulation of transferase activity 3.050845e-3
GO:0060452 positive regulation of cardiac muscle contraction 3.081647e-3
GO:0051905 establishment of pigment granule localization 3.137451e-3
GO:0034220 ion transmembrane transport 3.156596e-3
GO:0042127 regulation of cell proliferation 3.159075e-3
GO:2000117 negative regulation of cysteine-type endopeptidase activity 3.216154e-3
GO:0071674 mononuclear cell migration 3.216154e-3
GO:0033674 positive regulation of kinase activity 3.306406e-3
GO:0015918 sterol transport 3.330538e-3
GO:0048738 cardiac muscle tissue development 3.366793e-3
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 3.533764e-3
GO:0000278 mitotic cell cycle 3.546827e-3
GO:0090066 regulation of anatomical structure size 3.558695e-3
GO:0060437 lung growth 3.573384e-3
GO:0018209 peptidyl-serine modification 3.598149e-3
GO:0050819 negative regulation of coagulation 3.657358e-3
GO:0060255 regulation of macromolecule metabolic process 3.661755e-3
GO:0071615 oxidative deethylation 3.669680e-3
GO:0070184 mitochondrial tyrosyl-tRNA aminoacylation 3.669680e-3
GO:0009403 toxin biosynthetic process 3.669680e-3
GO:0046148 pigment biosynthetic process 3.732013e-3
GO:0048536 spleen development 3.781748e-3
GO:0033962 cytoplasmic mRNA processing body assembly 3.841961e-3
GO:0033169 histone H3-K9 demethylation 3.841961e-3
GO:0072040 negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis 3.861518e-3
GO:0060555 induction of necroptosis by extracellular signals 3.928184e-3
GO:0070295 renal water absorption 3.928184e-3
GO:0010466 negative regulation of peptidase activity 3.930813e-3
GO:0007605 sensory perception of sound 3.932378e-3
GO:0010745 negative regulation of macrophage derived foam cell differentiation 3.943087e-3
GO:0043046 DNA methylation involved in gamete generation 3.972016e-3
GO:0045994 positive regulation of translational initiation by iron 4.136112e-3
GO:0002037 negative regulation of L-glutamate transport 4.136112e-3
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 4.157484e-3
GO:0005997 xylulose metabolic process 4.157484e-3
GO:0048170 positive regulation of long-term neuronal synaptic plasticity 4.157484e-3
GO:0010874 regulation of cholesterol efflux 4.193920e-3
GO:0007229 integrin-mediated signaling pathway 4.241697e-3
GO:0031032 actomyosin structure organization 4.243998e-3
GO:0000060 protein import into nucleus, translocation 4.332130e-3
GO:0007094 mitotic cell cycle spindle assembly checkpoint 4.385902e-3
GO:0042221 response to chemical stimulus 4.415601e-3
GO:0090394 negative regulation of excitatory postsynaptic membrane potential 4.457683e-3
GO:0071840 cellular component organization or biogenesis 4.577874e-3
GO:0032369 negative regulation of lipid transport 4.609266e-3
GO:0051954 positive regulation of amine transport 4.616054e-3
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 4.660636e-3
GO:0060765 regulation of androgen receptor signaling pathway 4.729618e-3
GO:0071173 spindle assembly checkpoint 4.745356e-3
GO:0034504 protein localization to nucleus 4.780743e-3
GO:0006572 tyrosine catabolic process 4.804178e-3
GO:0071174 mitotic cell cycle spindle checkpoint 4.819970e-3
GO:0000492 box C/D snoRNP assembly 4.868476e-3
GO:0072017 distal tubule development 4.871703e-3
GO:0006417 regulation of translation 4.880206e-3
GO:0032925 regulation of activin receptor signaling pathway 4.884746e-3
GO:0045669 positive regulation of osteoblast differentiation 5.028973e-3
GO:0072080 nephron tubule development 5.063963e-3
GO:0034375 high-density lipoprotein particle remodeling 5.165417e-3
GO:0050954 sensory perception of mechanical stimulus 5.169934e-3
GO:0032508 DNA duplex unwinding 5.208682e-3
GO:0055114 oxidation-reduction process 5.230622e-3
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.249723e-3
GO:0071363 cellular response to growth factor stimulus 5.258179e-3
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 5.368639e-3
GO:0007015 actin filament organization 5.419557e-3
GO:0031577 spindle checkpoint 5.450884e-3
GO:0009581 detection of external stimulus 5.540514e-3
GO:0043412 macromolecule modification 5.543455e-3
GO:0052547 regulation of peptidase activity 5.620098e-3
GO:0002548 monocyte chemotaxis 5.626943e-3
GO:0010740 positive regulation of intracellular protein kinase cascade 5.655688e-3
GO:0032400 melanosome localization 5.723253e-3
GO:2000611 positive regulation of thyroid hormone generation 5.749678e-3
GO:0070988 demethylation 5.750969e-3
GO:0090084 negative regulation of inclusion body assembly 5.802493e-3
GO:0001661 conditioned taste aversion 5.948485e-3
GO:0016577 histone demethylation 6.054778e-3
GO:0051583 dopamine uptake 6.064804e-3
GO:0071316 cellular response to nicotine 6.072014e-3
GO:0060693 regulation of branching involved in salivary gland morphogenesis 6.082814e-3
GO:0009649 entrainment of circadian clock 6.082814e-3
GO:0050665 hydrogen peroxide biosynthetic process 6.090908e-3
GO:0051798 positive regulation of hair follicle development 6.090908e-3
GO:0051705 behavioral interaction between organisms 6.096860e-3
GO:0010875 positive regulation of cholesterol efflux 6.099849e-3
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 6.133424e-3
GO:0032854 positive regulation of Rap GTPase activity 6.133424e-3
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 6.192010e-3
GO:0070663 regulation of leukocyte proliferation 6.245907e-3
GO:0043010 camera-type eye development 6.262631e-3
GO:0048771 tissue remodeling 6.274782e-3
GO:0032392 DNA geometric change 6.274896e-3
GO:0009314 response to radiation 6.289276e-3
GO:0001558 regulation of cell growth 6.306872e-3
GO:0061326 renal tubule development 6.318811e-3
GO:0030259 lipid glycosylation 6.360511e-3
GO:0043266 regulation of potassium ion transport 6.418783e-3
GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein 6.427505e-3
GO:0002019 regulation of renal output by angiotensin 6.499041e-3
GO:0006811 ion transport 6.552362e-3
GO:0032926 negative regulation of activin receptor signaling pathway 6.573847e-3
GO:0031323 regulation of cellular metabolic process 6.591761e-3
GO:0006447 regulation of translational initiation by iron 6.635731e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0030488 tRNA methylation 1.542430e-90
GO:0006400 tRNA modification 3.580398e-68
GO:0001510 RNA methylation 4.011390e-60
GO:0009451 RNA modification 6.272802e-54
GO:0008033 tRNA processing 2.977294e-36
GO:0043414 macromolecule methylation 1.694760e-33
GO:0006399 tRNA metabolic process 1.122106e-29
GO:0032259 methylation 1.236355e-24
GO:0006730 one-carbon metabolic process 2.145465e-24
GO:0034470 ncRNA processing 3.475550e-22
GO:0034660 ncRNA metabolic process 2.575379e-18
GO:0014816 satellite cell differentiation 5.749989e-16
GO:0055114 oxidation-reduction process 6.624137e-14
GO:0043497 regulation of protein heterodimerization activity 1.668236e-11
GO:0060059 embryonic retina morphogenesis in camera-type eye 3.627202e-11
GO:0006694 steroid biosynthetic process 1.491774e-10
GO:0010172 embryonic body morphogenesis 1.641945e-10
GO:0046600 negative regulation of centriole replication 1.823049e-10
GO:0033617 mitochondrial respiratory chain complex IV assembly 3.292778e-10
GO:0001522 pseudouridine synthesis 2.129775e-9
GO:0000768 syncytium formation by plasma membrane fusion 2.470057e-9
GO:0045338 farnesyl diphosphate metabolic process 5.357443e-9
GO:0006974 response to DNA damage stimulus 6.653976e-9
GO:0006949 syncytium formation 1.746637e-8
GO:0051932 synaptic transmission, GABAergic 2.597959e-8
GO:0018963 phthalate metabolic process 4.183068e-8
GO:0021543 pallium development 5.498115e-8
GO:0045663 positive regulation of myoblast differentiation 6.163955e-8
GO:0046599 regulation of centriole replication 6.525927e-8
GO:2000177 regulation of neural precursor cell proliferation 6.651744e-8
GO:0018879 biphenyl metabolic process 8.848695e-8
GO:0007520 myoblast fusion 1.041619e-7
GO:0006396 RNA processing 1.159255e-7
GO:0018894 dibenzo-p-dioxin metabolic process 1.575132e-7
GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching 1.922036e-7
GO:0034551 mitochondrial respiratory chain complex III assembly 3.893258e-7
GO:0010845 positive regulation of reciprocal meiotic recombination 3.893258e-7
GO:2000179 positive regulation of neural precursor cell proliferation 5.089565e-7
GO:0034698 response to gonadotropin stimulus 8.002940e-7
GO:0016090 prenol metabolic process 8.337946e-7
GO:2000691 negative regulation of cardiac muscle cell myoblast differentiation 8.893995e-7
GO:0010659 cardiac muscle cell apoptosis 8.893995e-7
GO:0060042 retina morphogenesis in camera-type eye 1.316335e-6
GO:0090231 regulation of spindle checkpoint 1.392367e-6
GO:0051567 histone H3-K9 methylation 2.512717e-6
GO:0050935 iridophore differentiation 2.848353e-6
GO:0048937 lateral line nerve glial cell development 2.848353e-6
GO:0048643 positive regulation of skeletal muscle tissue development 3.087240e-6
GO:0033128 negative regulation of histone phosphorylation 3.301242e-6
GO:0030263 apoptotic chromosome condensation 5.656390e-6
GO:0035914 skeletal muscle cell differentiation 6.477847e-6
GO:0016126 sterol biosynthetic process 6.799683e-6
GO:0070327 thyroid hormone transport 1.012242e-5
GO:0010824 regulation of centrosome duplication 1.133587e-5
GO:0043951 negative regulation of cAMP-mediated signaling 1.144650e-5
GO:0010976 positive regulation of neuron projection development 1.221651e-5
GO:0070293 renal absorption 1.411767e-5
GO:0032354 response to follicle-stimulating hormone stimulus 1.475478e-5
GO:0016577 histone demethylation 1.986003e-5
GO:0009115 xanthine catabolic process 2.106382e-5
GO:0048880 sensory system development 2.223991e-5
GO:0034968 histone lysine methylation 2.377265e-5
GO:0001757 somite specification 2.537407e-5
GO:0006482 protein demethylation 2.994792e-5
GO:0045665 negative regulation of neuron differentiation 3.085304e-5
GO:0045661 regulation of myoblast differentiation 3.110931e-5
GO:0033554 cellular response to stress 4.056377e-5
GO:0045844 positive regulation of striated muscle tissue development 4.434407e-5
GO:0045666 positive regulation of neuron differentiation 4.555881e-5
GO:0044281 small molecule metabolic process 4.800599e-5
GO:0006479 protein methylation 5.053202e-5
GO:0014902 myotube differentiation 5.169133e-5
GO:0017004 cytochrome complex assembly 5.813314e-5
GO:0046605 regulation of centrosome cycle 5.856244e-5
GO:0032094 response to food 5.906984e-5
GO:0046110 xanthine metabolic process 7.786025e-5
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 8.169865e-5
GO:0043412 macromolecule modification 8.491416e-5
GO:0033127 regulation of histone phosphorylation 8.947279e-5
GO:0010520 regulation of reciprocal meiotic recombination 1.023714e-4
GO:0006702 androgen biosynthetic process 1.052539e-4
GO:0008202 steroid metabolic process 1.124485e-4
GO:0051057 positive regulation of small GTPase mediated signal transduction 1.387195e-4
GO:0006344 maintenance of chromatin silencing 1.497415e-4
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA 1.613980e-4
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.624892e-4
GO:0000132 establishment of mitotic spindle orientation 1.725884e-4
GO:0007405 neuroblast proliferation 1.797533e-4
GO:0070534 protein K63-linked ubiquitination 1.873272e-4
GO:0060631 regulation of meiosis I 1.895641e-4
GO:0006145 purine base catabolic process 1.895641e-4
GO:0070076 histone lysine demethylation 1.901286e-4
GO:0031424 keratinization 1.965656e-4
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.978149e-4
GO:0060575 intestinal epithelial cell differentiation 2.091262e-4
GO:0070295 renal water absorption 2.122686e-4
GO:0048846 axon extension involved in axon guidance 2.149482e-4
GO:0040001 establishment of mitotic spindle localization 2.192005e-4
GO:0035674 tricarboxylic acid transmembrane transport 2.299279e-4
GO:0009597 detection of virus 2.299279e-4
GO:0050954 sensory perception of mechanical stimulus 2.617794e-4
GO:0006833 water transport 2.624658e-4
GO:0006720 isoprenoid metabolic process 2.637332e-4
GO:0010900 negative regulation of phosphatidylcholine catabolic process 2.638276e-4
GO:0000185 activation of MAPKKK activity 2.638276e-4
GO:0021766 hippocampus development 2.751812e-4
GO:0051026 chiasma assembly 2.929162e-4
GO:0007605 sensory perception of sound 3.042052e-4
GO:0008209 androgen metabolic process 3.231654e-4
GO:0042445 hormone metabolic process 3.466633e-4
GO:0003097 renal water transport 3.583172e-4
GO:0033108 mitochondrial respiratory chain complex assembly 3.846178e-4
GO:0050891 multicellular organismal water homeostasis 4.076127e-4
GO:0006706 steroid catabolic process 4.255825e-4
GO:0031442 positive regulation of mRNA 3'-end processing 4.586760e-4
GO:0016575 histone deacetylation 4.687639e-4
GO:0045104 intermediate filament cytoskeleton organization 4.741982e-4
GO:0007288 sperm axoneme assembly 4.763726e-4
GO:0021987 cerebral cortex development 5.321854e-4
GO:0042044 fluid transport 5.486374e-4
GO:0045103 intermediate filament-based process 5.949440e-4
GO:0006987 activation of signaling protein activity involved in unfolded protein response 6.217627e-4
GO:0009296 flagellum assembly 6.420697e-4
GO:0015074 DNA integration 6.679426e-4
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 6.714269e-4
GO:0001578 microtubule bundle formation 6.765070e-4
GO:0051293 establishment of spindle localization 6.876368e-4
GO:0006637 acyl-CoA metabolic process 6.876368e-4
GO:0016571 histone methylation 6.933365e-4
GO:0021537 telencephalon development 7.525596e-4
GO:0007600 sensory perception 7.646715e-4
GO:0007519 skeletal muscle tissue development 8.200841e-4
GO:0015746 citrate transport 8.313564e-4
GO:0070988 demethylation 8.435077e-4
GO:0002088 lens development in camera-type eye 8.549976e-4
GO:0051602 response to electrical stimulus 8.667447e-4
GO:0061014 positive regulation of mRNA catabolic process 8.777021e-4
GO:0031440 regulation of mRNA 3'-end processing 8.777021e-4
GO:0043393 regulation of protein binding 9.270400e-4
GO:0050767 regulation of neurogenesis 9.320467e-4
GO:0071371 cellular response to gonadotropin stimulus 9.603089e-4
GO:0048821 erythrocyte development 9.823563e-4
GO:0043064 flagellum organization 9.886441e-4
GO:0033239 negative regulation of cellular amine metabolic process 1.008197e-3
GO:0009581 detection of external stimulus 1.011005e-3
GO:0050756 fractalkine metabolic process 1.013550e-3
GO:0033595 response to genistein 1.013550e-3
GO:0006701 progesterone biosynthetic process 1.013550e-3
GO:0016070 RNA metabolic process 1.015403e-3
GO:0007224 smoothened signaling pathway 1.027264e-3
GO:0072337 modified amino acid transport 1.095854e-3
GO:0060600 dichotomous subdivision of an epithelial terminal unit 1.134126e-3
GO:0030104 water homeostasis 1.134126e-3
GO:0035088 establishment or maintenance of apical/basal cell polarity 1.146078e-3
GO:0071422 succinate transmembrane transport 1.219130e-3
GO:0015991 ATP hydrolysis coupled proton transport 1.228064e-3
GO:0045198 establishment of epithelial cell apical/basal polarity 1.359453e-3
GO:0051297 centrosome organization 1.376433e-3
GO:0070670 response to interleukin-4 1.378253e-3
GO:0060538 skeletal muscle organ development 1.432361e-3
GO:0060696 regulation of phospholipid catabolic process 1.447381e-3
GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration 1.449165e-3
GO:0008535 respiratory chain complex IV assembly 1.549804e-3
GO:0071799 cellular response to prostaglandin D stimulus 1.573401e-3
GO:0048286 lung alveolus development 1.588457e-3
GO:0071557 histone H3-K27 demethylation 1.704671e-3
GO:0035574 histone H4-K20 demethylation 1.704671e-3
GO:0034447 very-low-density lipoprotein particle clearance 1.770488e-3
GO:0032075 positive regulation of nuclease activity 1.809781e-3
GO:0008210 estrogen metabolic process 1.921411e-3
GO:0008299 isoprenoid biosynthetic process 1.943623e-3
GO:0006950 response to stress 2.131449e-3
GO:0045664 regulation of neuron differentiation 2.184304e-3
GO:0021761 limbic system development 2.225657e-3
GO:0042107 cytokine metabolic process 2.287352e-3
GO:0006301 postreplication repair 2.287352e-3
GO:0071372 cellular response to follicle-stimulating hormone stimulus 2.308402e-3
GO:0031023 microtubule organizing center organization 2.396607e-3
GO:0043949 regulation of cAMP-mediated signaling 2.421988e-3
GO:0006703 estrogen biosynthetic process 2.570675e-3
GO:0061370 testosterone biosynthetic process 2.633432e-3
GO:0070869 heterochromatin formation involved in chromatin silencing 2.633432e-3
GO:0035082 axoneme assembly 2.725866e-3
GO:0003091 renal water homeostasis 2.725866e-3
GO:0032350 regulation of hormone metabolic process 2.823806e-3
GO:0001708 cell fate specification 2.886645e-3
GO:0032648 regulation of interferon-beta production 2.887495e-3
GO:0048863 stem cell differentiation 2.907116e-3
GO:0050957 equilibrioception 2.913107e-3
GO:0016125 sterol metabolic process 3.027059e-3
GO:0032981 mitochondrial respiratory chain complex I assembly 3.056407e-3
GO:0009582 detection of abiotic stimulus 3.114938e-3
GO:0072267 metanephric capsule specification 3.248672e-3
GO:0015966 diadenosine tetraphosphate biosynthetic process 3.248672e-3
GO:0048632 negative regulation of skeletal muscle tissue growth 3.248672e-3
GO:0090030 regulation of steroid hormone biosynthetic process 3.314887e-3
GO:0051960 regulation of nervous system development 3.378378e-3
GO:0051905 establishment of pigment granule localization 3.605030e-3
GO:0030011 maintenance of cell polarity 3.802631e-3
GO:0008610 lipid biosynthetic process 3.808394e-3
GO:0072321 chaperone-mediated protein transport 3.823299e-3
GO:0001845 phagolysosome assembly 3.823299e-3
GO:0016202 regulation of striated muscle tissue development 3.958083e-3
GO:0010894 negative regulation of steroid biosynthetic process 4.004967e-3
GO:0031331 positive regulation of cellular catabolic process 4.077733e-3
GO:0010817 regulation of hormone levels 4.112000e-3
GO:0009896 positive regulation of catabolic process 4.148529e-3
GO:0034197 triglyceride transport 4.295108e-3
GO:0007597 blood coagulation, intrinsic pathway 4.295108e-3
GO:0030540 female genitalia development 4.338574e-3
GO:0006629 lipid metabolic process 4.365080e-3
GO:0048634 regulation of muscle organ development 4.466388e-3
GO:0061013 regulation of mRNA catabolic process 4.467801e-3
GO:0090073 positive regulation of protein homodimerization activity 4.670933e-3
GO:0009612 response to mechanical stimulus 4.718774e-3
GO:0006172 ADP biosynthetic process 4.771514e-3
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 4.908277e-3
GO:0018026 peptidyl-lysine monomethylation 4.908277e-3
GO:0044341 sodium-dependent phosphate transport 4.962871e-3
GO:0051890 regulation of cardioblast differentiation 5.079440e-3
GO:0042403 thyroid hormone metabolic process 5.168408e-3
GO:0048484 enteric nervous system development 5.235310e-3
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 5.408389e-3
GO:2000612 regulation of thyroid-stimulating hormone secretion 5.475856e-3
GO:0060045 positive regulation of cardiac muscle cell proliferation 5.487041e-3
GO:0006342 chromatin silencing 5.626101e-3
GO:0060441 epithelial tube branching involved in lung morphogenesis 5.910326e-3
GO:0051918 negative regulation of fibrinolysis 6.095158e-3
GO:0035024 negative regulation of Rho protein signal transduction 6.095158e-3
GO:0045836 positive regulation of meiosis 6.095158e-3
GO:0071305 cellular response to vitamin D 6.325260e-3
GO:0050685 positive regulation of mRNA processing 6.325260e-3
GO:0032479 regulation of type I interferon production 6.357127e-3
GO:0019934 cGMP-mediated signaling 6.357127e-3
GO:0007596 blood coagulation 6.376538e-3
GO:0070936 protein K48-linked ubiquitination 6.438781e-3
GO:0071918 urea transmembrane transport 6.438831e-3
GO:0032727 positive regulation of interferon-alpha production 6.438831e-3
GO:0090304 nucleic acid metabolic process 6.566839e-3
GO:0090031 positive regulation of steroid hormone biosynthetic process 6.677173e-3
GO:0032352 positive regulation of hormone metabolic process 6.733180e-3
GO:0050892 intestinal absorption 6.762556e-3
GO:0034633 retinol transport 6.787338e-3
GO:0030186 melatonin metabolic process 6.787338e-3
GO:0090076 relaxation of skeletal muscle 6.795422e-3
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 6.795422e-3
GO:0060041 retina development in camera-type eye 6.827159e-3
GO:0007599 hemostasis 6.848576e-3
GO:0051056 regulation of small GTPase mediated signal transduction 6.947364e-3
GO:0006476 protein deacetylation 7.005978e-3
GO:0045541 negative regulation of cholesterol biosynthetic process 7.062088e-3
GO:0042448 progesterone metabolic process 7.186161e-3
GO:0002065 columnar/cuboidal epithelial cell differentiation 7.196172e-3
GO:0034754 cellular hormone metabolic process 7.263419e-3
GO:0048641 regulation of skeletal muscle tissue development 7.317684e-3
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 7.638407e-3
GO:0006101 citrate metabolic process 7.638407e-3
GO:0035425 autocrine signaling 7.719876e-3
GO:0060014 granulosa cell differentiation 7.719876e-3
GO:0071236 cellular response to antibiotic 7.840309e-3
GO:0090184 positive regulation of kidney development 7.859844e-3
GO:0035601 protein deacylation 8.029295e-3
GO:0032025 response to cobalt ion 8.084511e-3
GO:0035458 cellular response to interferon-beta 8.108840e-3
GO:0010985 negative regulation of lipoprotein particle clearance 8.108840e-3
GO:0007339 binding of sperm to zona pellucida 8.116095e-3
GO:0046686 response to cadmium ion 8.184480e-3
GO:0035623 renal glucose absorption 8.226045e-3
GO:0042537 benzene-containing compound metabolic process 8.444687e-3
GO:0032069 regulation of nuclease activity 8.547353e-3
GO:0071346 cellular response to interferon-gamma 8.609023e-3
GO:0060395 SMAD protein signal transduction 8.688234e-3
GO:0034382 chylomicron remnant clearance 8.816063e-3
GO:0051005 negative regulation of lipoprotein lipase activity 8.816063e-3
GO:0009415 response to water 8.816063e-3
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 9.051734e-3
GO:0044339 canonical Wnt receptor signaling pathway involved in osteoblast differentiation 9.140694e-3
GO:0022007 convergent extension involved in neural plate elongation 9.140694e-3
GO:0044338 canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation 9.140694e-3
GO:0032008 positive regulation of TOR signaling cascade 9.185152e-3
GO:0001539 ciliary or flagellar motility 9.185152e-3
GO:0035089 establishment of apical/basal cell polarity 9.524210e-3
GO:0051149 positive regulation of muscle cell differentiation 9.601491e-3
GO:0060420 regulation of heart growth 9.713784e-3
GO:0006426 glycyl-tRNA aminoacylation 9.788536e-3
GO:0006695 cholesterol biosynthetic process 9.854590e-3
GO:0050702 interleukin-1 beta secretion 9.904463e-3
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 1.003869e-2
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1.015770e-2
GO:0033238 regulation of cellular amine metabolic process 1.015770e-2
GO:0006929 substrate-dependent cell migration 1.015770e-2
GO:0031122 cytoplasmic microtubule organization 1.024486e-2
GO:0030859 polarized epithelial cell differentiation 1.057083e-2
GO:0051917 regulation of fibrinolysis 1.057837e-2
GO:0045039 protein import into mitochondrial inner membrane 1.070424e-2
GO:0032611 interleukin-1 beta production 1.070424e-2
GO:0021542 dentate gyrus development 1.072838e-2
GO:0002042 cell migration involved in sprouting angiogenesis 1.076793e-2
GO:0035036 sperm-egg recognition 1.091950e-2
GO:0043434 response to peptide hormone stimulus 1.104525e-2
GO:0018904 organic ether metabolic process 1.117227e-2
GO:0051875 pigment granule localization 1.119091e-2
GO:2000178 negative regulation of neural precursor cell proliferation 1.125664e-2
GO:2000142 regulation of transcription initiation, DNA-dependent 1.132198e-2
GO:0042780 tRNA 3'-end processing 1.147144e-2
GO:0034553 mitochondrial respiratory chain complex II assembly 1.147144e-2
GO:0071276 cellular response to cadmium ion 1.154033e-2
GO:0048668 collateral sprouting 1.154033e-2
GO:0010984 regulation of lipoprotein particle clearance 1.162506e-2
GO:0048593 camera-type eye morphogenesis 1.197326e-2
GO:0001839 neural plate morphogenesis 1.227536e-2
GO:0035372 protein localization to microtubule 1.241297e-2
GO:0010724 regulation of definitive erythrocyte differentiation 1.241297e-2
GO:0048742 regulation of skeletal muscle fiber development 1.251700e-2
GO:0015698 inorganic anion transport 1.264106e-2
GO:0007163 establishment or maintenance of cell polarity 1.270621e-2
GO:0043648 dicarboxylic acid metabolic process 1.302780e-2
GO:0046580 negative regulation of Ras protein signal transduction 1.308523e-2
GO:0046113 nucleobase catabolic process 1.313114e-2
GO:0060536 cartilage morphogenesis 1.324518e-2
GO:0009611 response to wounding 1.330147e-2
GO:0010171 body morphogenesis 1.332639e-2
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 1.350382e-2
GO:0045668 negative regulation of osteoblast differentiation 1.355288e-2
GO:0030324 lung development 1.368895e-2
GO:0007422 peripheral nervous system development 1.394739e-2
GO:0060347 heart trabecula formation 1.396793e-2
GO:0045989 positive regulation of striated muscle contraction 1.396793e-2
GO:0035414 negative regulation of catenin import into nucleus 1.396793e-2
GO:0018022 peptidyl-lysine methylation 1.396793e-2
GO:0048675 axon extension 1.405608e-2
GO:0042446 hormone biosynthetic process 1.449716e-2
GO:0030901 midbrain development 1.460413e-2
GO:0071375 cellular response to peptide hormone stimulus 1.504294e-2
GO:0030038 contractile actin filament bundle assembly 1.518530e-2
GO:0035912 dorsal aorta morphogenesis 1.518530e-2
GO:0046785 microtubule polymerization 1.525246e-2
GO:0002230 positive regulation of defense response to virus by host 1.525246e-2
GO:0030323 respiratory tube development 1.537351e-2
GO:0043149 stress fiber assembly 1.563847e-2
GO:0051058 negative regulation of small GTPase mediated signal transduction 1.568734e-2
GO:0050974 detection of mechanical stimulus involved in sensory perception 1.581575e-2
GO:0000413 protein peptidyl-prolyl isomerization 1.596722e-2
GO:0009583 detection of light stimulus 1.646501e-2
GO:0030010 establishment of cell polarity 1.672478e-2
GO:0035519 protein K29-linked ubiquitination 1.720983e-2
GO:0015959 diadenosine polyphosphate metabolic process 1.720983e-2
GO:0008057 eye pigment granule organization 1.720983e-2
GO:0005997 xylulose metabolic process 1.720983e-2
GO:0006820 anion transport 1.725609e-2
GO:0032647 regulation of interferon-alpha production 1.733177e-2
GO:0002344 B cell affinity maturation 1.733177e-2
GO:0010467 gene expression 1.754132e-2
GO:0008090 retrograde axon cargo transport 1.764720e-2
GO:0030318 melanocyte differentiation 1.773182e-2
GO:0033522 histone H2A ubiquitination 1.796630e-2
GO:0050810 regulation of steroid biosynthetic process 1.818191e-2
GO:0048259 regulation of receptor-mediated endocytosis 1.865527e-2
GO:0006071 glycerol metabolic process 1.905903e-2
GO:0034097 response to cytokine stimulus 1.909744e-2
GO:0010164 response to cesium ion 1.934193e-2
GO:0015734 taurine transport 1.934193e-2
GO:0006481 C-terminal protein methylation 1.934193e-2
GO:0046885 regulation of hormone biosynthetic process 1.937029e-2
GO:0050701 interleukin-1 secretion 1.956124e-2
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process 1.956124e-2
GO:0070193 synaptonemal complex organization 1.956138e-2
GO:0050931 pigment cell differentiation 1.981150e-2
GO:0043496 regulation of protein homodimerization activity 2.052092e-2
GO:0032612 interleukin-1 production 2.073246e-2
GO:0045652 regulation of megakaryocyte differentiation 2.105984e-2
GO:0046886 positive regulation of hormone biosynthetic process 2.129234e-2
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration 2.157852e-2
GO:0043312 neutrophil degranulation 2.157852e-2
GO:0070544 histone H3-K36 demethylation 2.164331e-2
GO:0051561 elevation of mitochondrial calcium ion concentration 2.164331e-2
GO:0035690 cellular response to drug 2.167464e-2
GO:0050688 regulation of defense response to virus 2.279710e-2
GO:0002446 neutrophil mediated immunity 2.283858e-2
GO:0050982 detection of mechanical stimulus 2.285105e-2
GO:0045814 negative regulation of gene expression, epigenetic 2.285105e-2
GO:0051186 cofactor metabolic process 2.382119e-2
GO:0048631 regulation of skeletal muscle tissue growth 2.391662e-2
GO:0048592 eye morphogenesis 2.436521e-2
GO:0030828 positive regulation of cGMP biosynthetic process 2.447233e-2
GO:0015840 urea transport 2.447233e-2
GO:0040020 regulation of meiosis 2.484362e-2
GO:0006084 acetyl-CoA metabolic process 2.500493e-2
GO:0070509 calcium ion import 2.520724e-2
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production 2.525561e-2
GO:0032658 regulation of interleukin-15 production 2.525561e-2
GO:0030195 negative regulation of blood coagulation 2.571826e-2
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2.579432e-2
GO:0051488 activation of anaphase-promoting complex activity 2.579432e-2
GO:0034770 histone H4-K20 methylation 2.579432e-2
GO:0002011 morphogenesis of an epithelial sheet 2.591259e-2
GO:0043526 neuroprotection 2.620996e-2
GO:0070059 apoptosis in response to endoplasmic reticulum stress 2.634488e-2
GO:0072076 nephrogenic mesenchyme development 2.635329e-2
GO:0060043 regulation of cardiac muscle cell proliferation 2.685558e-2
GO:0019400 alditol metabolic process 2.701252e-2
GO:0031057 negative regulation of histone modification 2.757421e-2
GO:0050684 regulation of mRNA processing 2.785012e-2
GO:0050878 regulation of body fluid levels 2.875518e-2
GO:0034766 negative regulation of ion transmembrane transport 2.888564e-2
GO:0071464 cellular response to hydrostatic pressure 2.888564e-2
GO:0034141 positive regulation of toll-like receptor 3 signaling pathway 2.888564e-2
GO:0007379 segment specification 2.958972e-2
GO:0048515 spermatid differentiation 2.972889e-2
GO:0030513 positive regulation of BMP signaling pathway 3.001853e-2
GO:0051445 regulation of meiotic cell cycle 3.050151e-2
GO:0001840 neural plate development 3.117884e-2
GO:0010893 positive regulation of steroid biosynthetic process 3.137755e-2
GO:0007099 centriole replication 3.145757e-2
GO:0042113 B cell activation 3.168291e-2
GO:0060192 negative regulation of lipase activity 3.209098e-2
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 3.295313e-2
GO:0035567 non-canonical Wnt receptor signaling pathway 3.298842e-2
GO:0000183 chromatin silencing at rDNA 3.333835e-2
GO:0060828 regulation of canonical Wnt receptor signaling pathway 3.360571e-2
GO:0046618 drug export 3.422619e-2
GO:0010735 positive regulation of transcription via serum response element binding 3.422619e-2
GO:0042886 amide transport 3.451294e-2
GO:0042472 inner ear morphogenesis 3.471171e-2
GO:0042742 defense response to bacterium 3.555577e-2
GO:0032728 positive regulation of interferon-beta production 3.558296e-2
GO:0007521 muscle cell fate determination 3.558296e-2
GO:0048261 negative regulation of receptor-mediated endocytosis 3.562552e-2
GO:0045717 negative regulation of fatty acid biosynthetic process 3.654511e-2
GO:0032092 positive regulation of protein binding 3.759855e-2
GO:0042666 negative regulation of ectodermal cell fate specification 3.764337e-2
GO:0060965 negative regulation of gene silencing by miRNA 3.764337e-2
GO:0070933 histone H4 deacetylation 3.771597e-2
GO:0060437 lung growth 3.771597e-2
GO:0060535 trachea cartilage morphogenesis 3.771597e-2
GO:0055021 regulation of cardiac muscle tissue growth 3.815466e-2
GO:0045732 positive regulation of protein catabolic process 3.824482e-2
GO:0000226 microtubule cytoskeleton organization 3.856333e-2
GO:0051865 protein autoubiquitination 3.857483e-2
GO:0006817 phosphate ion transport 3.910985e-2
GO:0050973 detection of mechanical stimulus involved in equilibrioception 3.937243e-2
GO:0045653 negative regulation of megakaryocyte differentiation 3.937243e-2
GO:0050691 regulation of defense response to virus by host 3.939082e-2
GO:0060026 convergent extension 3.939082e-2
GO:0030220 platelet formation 3.939082e-2
GO:0015672 monovalent inorganic cation transport 3.985897e-2
GO:0033561 regulation of water loss via skin 3.991634e-2
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 4.106525e-2
GO:0060117 auditory receptor cell development 4.136077e-2
GO:0031346 positive regulation of cell projection organization 4.137074e-2
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway 4.169636e-2
GO:0060284 regulation of cell development 4.186686e-2
GO:0051657 maintenance of organelle location 4.236767e-2
GO:0033169 histone H3-K9 demethylation 4.279423e-2
GO:0021827 postnatal olfactory bulb interneuron migration 4.279423e-2
GO:0055062 phosphate ion homeostasis 4.282902e-2
GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger 4.282902e-2
GO:2000594 positive regulation of metanephric DCT cell differentiation 4.288591e-2
GO:0039003 pronephric field specification 4.288591e-2
GO:0072305 negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis 4.288591e-2
GO:0006099 tricarboxylic acid cycle 4.362668e-2
GO:0014819 regulation of skeletal muscle contraction 4.411146e-2
GO:0048240 sperm capacitation 4.442546e-2
GO:0032375 negative regulation of cholesterol transport 4.442546e-2
GO:0006139 nucleobase-containing compound metabolic process 4.447376e-2
GO:0046519 sphingoid metabolic process 4.448684e-2
GO:0034392 negative regulation of smooth muscle cell apoptosis 4.455913e-2
GO:0021847 ventricular zone neuroblast division 4.455913e-2
GO:0019751 polyol metabolic process 4.486651e-2
GO:0045933 positive regulation of muscle contraction 4.505073e-2
GO:0007286 spermatid development 4.581561e-2
GO:0016101 diterpenoid metabolic process 4.583754e-2
GO:0042732 D-xylose metabolic process 4.593507e-2
GO:0072003 kidney rudiment formation 4.593507e-2
GO:0044111 development involved in symbiotic interaction 4.593507e-2
GO:0006398 histone mRNA 3'-end processing 4.593507e-2
GO:0010768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage 4.593507e-2
GO:0019089 transmission of virus 4.593507e-2
GO:0018208 peptidyl-proline modification 4.616588e-2
GO:0007602 phototransduction 4.630052e-2
GO:0051656 establishment of organelle localization 4.642436e-2
GO:0061384 heart trabecular morphogenesis 4.654205e-2
GO:0030431 sleep 4.654205e-2
GO:0045940 positive regulation of steroid metabolic process 4.694009e-2
GO:0021869 forebrain ventricular zone progenitor cell division 4.808676e-2
GO:0051904 pigment granule transport 4.819575e-2
GO:0002339 B cell selection 4.819575e-2
GO:0009414 response to water deprivation 4.819575e-2
GO:0040018 positive regulation of multicellular organism growth 4.826516e-2
GO:0007214 gamma-aminobutyric acid signaling pathway 4.871755e-2
GO:0043410 positive regulation of MAPKKK cascade 4.904978e-2
GO:0031639 plasminogen activation 4.906130e-2
GO:0006603 phosphocreatine metabolic process 4.906130e-2
GO:0050819 negative regulation of coagulation 4.907386e-2
GO:0060541 respiratory system development 4.914060e-2
GO:0050877 neurological system process 4.969269e-2
GO:0007129 synapsis 4.982742e-2
GO:0060125 negative regulation of growth hormone secretion 4.987380e-2
GO:0051463 negative regulation of cortisol secretion 4.987380e-2
GO:0045769 negative regulation of asymmetric cell division 4.987380e-2