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Novel motif:159

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name:motif159_ACACATACTACA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0032501 multicellular organismal process 1.387096e-25
GO:0043503 skeletal muscle fiber adaptation 1.296715e-24
GO:0043500 muscle adaptation 2.553193e-20
GO:0001970 positive regulation of activation of membrane attack complex 1.748939e-19
GO:0014829 vascular smooth muscle contraction 2.431212e-19
GO:0007275 multicellular organismal development 6.618622e-18
GO:0009611 response to wounding 7.574499e-18
GO:0048731 system development 1.250705e-17
GO:0006954 inflammatory response 1.267379e-17
GO:0048856 anatomical structure development 7.834971e-17
GO:0048513 organ development 9.925624e-17
GO:0032502 developmental process 1.403491e-16
GO:0014888 striated muscle adaptation 9.297441e-16
GO:0043501 skeletal muscle adaptation 9.341357e-16
GO:0050896 response to stimulus 1.380573e-15
GO:0010575 positive regulation vascular endothelial growth factor production 2.768358e-15
GO:0001798 positive regulation of type IIa hypersensitivity 4.101675e-15
GO:0031032 actomyosin structure organization 8.758079e-14
GO:0065008 regulation of biological quality 1.200358e-13
GO:0008588 release of cytoplasmic sequestered NF-kappaB 2.576546e-13
GO:0007586 digestion 2.915237e-13
GO:0010927 cellular component assembly involved in morphogenesis 7.904525e-13
GO:0001819 positive regulation of cytokine production 1.088292e-12
GO:0006952 defense response 1.334538e-12
GO:0010954 positive regulation of protein processing 1.823469e-12
GO:0030239 myofibril assembly 3.770066e-12
GO:0030449 regulation of complement activation 1.148380e-11
GO:0003012 muscle system process 1.456485e-11
GO:0043206 fibril organization 2.310727e-11
GO:0051592 response to calcium ion 2.368619e-11
GO:0065007 biological regulation 3.013365e-11
GO:0032103 positive regulation of response to external stimulus 3.808445e-11
GO:0046578 regulation of Ras protein signal transduction 4.011804e-11
GO:0042310 vasoconstriction 4.388906e-11
GO:0006939 smooth muscle contraction 4.519576e-11
GO:0030154 cell differentiation 5.559853e-11
GO:0030003 cellular cation homeostasis 5.617177e-11
GO:0006957 complement activation, alternative pathway 6.910931e-11
GO:0010574 regulation of vascular endothelial growth factor production 7.821501e-11
GO:0002885 positive regulation of hypersensitivity 9.336289e-11
GO:0050729 positive regulation of inflammatory response 1.119802e-10
GO:0080134 regulation of response to stress 1.442124e-10
GO:0030029 actin filament-based process 1.574484e-10
GO:0030004 cellular monovalent inorganic cation homeostasis 1.873361e-10
GO:0071732 cellular response to nitric oxide 2.370830e-10
GO:0002376 immune system process 3.181218e-10
GO:0007154 cell communication 3.420516e-10
GO:0031349 positive regulation of defense response 3.469204e-10
GO:0045851 pH reduction 3.995588e-10
GO:0051453 regulation of intracellular pH 4.672579e-10
GO:0048869 cellular developmental process 4.883684e-10
GO:0009605 response to external stimulus 4.892793e-10
GO:0016192 vesicle-mediated transport 6.802390e-10
GO:0006875 cellular metal ion homeostasis 7.084567e-10
GO:0051452 intracellular pH reduction 7.983904e-10
GO:0006955 immune response 8.184618e-10
GO:0009888 tissue development 8.283199e-10
GO:0030641 regulation of cellular pH 9.307942e-10
GO:0006950 response to stress 9.885772e-10
GO:0008283 cell proliferation 1.041125e-9
GO:0032101 regulation of response to external stimulus 1.115796e-9
GO:0002883 regulation of hypersensitivity 1.314629e-9
GO:0048583 regulation of response to stimulus 1.318647e-9
GO:0007155 cell adhesion 1.376954e-9
GO:0042060 wound healing 1.853952e-9
GO:0023052 signaling 2.317765e-9
GO:0045214 sarcomere organization 2.403065e-9
GO:0070252 actin-mediated cell contraction 2.539359e-9
GO:0021761 limbic system development 3.396072e-9
GO:2001021 negative regulation of response to DNA damage stimulus 3.617490e-9
GO:0051179 localization 3.749430e-9
GO:0030049 muscle filament sliding 3.756081e-9
GO:0043090 amino acid import 4.203897e-9
GO:0030277 maintenance of gastrointestinal epithelium 4.208829e-9
GO:0051716 cellular response to stimulus 4.543355e-9
GO:0007035 vacuolar acidification 4.761148e-9
GO:0055065 metal ion homeostasis 7.021742e-9
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 7.561061e-9
GO:0051239 regulation of multicellular organismal process 8.057460e-9
GO:0009991 response to extracellular stimulus 8.210817e-9
GO:0055080 cation homeostasis 8.360913e-9
GO:0051050 positive regulation of transport 9.178819e-9
GO:0016197 endosome transport 9.744951e-9
GO:0006936 muscle contraction 9.812409e-9
GO:0009653 anatomical structure morphogenesis 1.007666e-8
GO:0003008 system process 1.107003e-8
GO:0070613 regulation of protein processing 1.146508e-8
GO:0045807 positive regulation of endocytosis 1.148117e-8
GO:0009612 response to mechanical stimulus 1.227227e-8
GO:0006810 transport 1.430428e-8
GO:0050766 positive regulation of phagocytosis 1.431493e-8
GO:0007186 G-protein coupled receptor protein signaling pathway 1.698646e-8
GO:0051234 establishment of localization 1.749626e-8
GO:0051056 regulation of small GTPase mediated signal transduction 1.992770e-8
GO:0042098 T cell proliferation 2.054569e-8
GO:0007166 cell surface receptor linked signaling pathway 2.162171e-8
GO:0050727 regulation of inflammatory response 2.430894e-8
GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport 2.748754e-8
GO:0007173 epidermal growth factor receptor signaling pathway 3.054078e-8
GO:0007584 response to nutrient 3.099635e-8
GO:0031347 regulation of defense response 3.433117e-8
GO:0043067 regulation of programmed cell death 3.460266e-8
GO:0051240 positive regulation of multicellular organismal process 3.689020e-8
GO:0006879 cellular iron ion homeostasis 3.834600e-8
GO:0045766 positive regulation of angiogenesis 4.040626e-8
GO:0001817 regulation of cytokine production 4.323454e-8
GO:0010951 negative regulation of endopeptidase activity 4.611958e-8
GO:0048518 positive regulation of biological process 4.631956e-8
GO:0006788 heme oxidation 4.813107e-8
GO:0010941 regulation of cell death 5.066357e-8
GO:0021854 hypothalamus development 5.442830e-8
GO:0033591 response to L-ascorbic acid 5.481414e-8
GO:0016043 cellular component organization 6.761836e-8
GO:0002708 positive regulation of lymphocyte mediated immunity 6.798199e-8
GO:0002675 positive regulation of acute inflammatory response 7.383818e-8
GO:0007218 neuropeptide signaling pathway 8.178000e-8
GO:0051877 pigment granule aggregation in cell center 8.681776e-8
GO:0030048 actin filament-based movement 9.565283e-8
GO:0042981 regulation of apoptosis 9.733923e-8
GO:0032642 regulation of chemokine production 9.849889e-8
GO:0046697 decidualization 1.060210e-7
GO:0043092 L-amino acid import 1.099352e-7
GO:0014910 regulation of smooth muscle cell migration 1.114579e-7
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1.114742e-7
GO:0045765 regulation of angiogenesis 1.220346e-7
GO:0070849 response to epidermal growth factor stimulus 1.310219e-7
GO:0009628 response to abiotic stimulus 1.478869e-7
GO:0007320 insemination 1.585651e-7
GO:0014866 skeletal myofibril assembly 1.633864e-7
GO:0042592 homeostatic process 1.656237e-7
GO:0060216 definitive hemopoiesis 1.789169e-7
GO:2000026 regulation of multicellular organismal development 2.010334e-7
GO:0030036 actin cytoskeleton organization 2.022020e-7
GO:0002821 positive regulation of adaptive immune response 2.118841e-7
GO:0032781 positive regulation of ATPase activity 2.123803e-7
GO:0006956 complement activation 2.208848e-7
GO:0042730 fibrinolysis 2.595788e-7
GO:0040007 growth 2.609868e-7
GO:0007165 signal transduction 3.203296e-7
GO:0042346 positive regulation of NF-kappaB import into nucleus 3.336120e-7
GO:0051649 establishment of localization in cell 3.598601e-7
GO:0051641 cellular localization 4.050825e-7
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 4.342046e-7
GO:0050789 regulation of biological process 4.900484e-7
GO:0050794 regulation of cellular process 5.649233e-7
GO:0030198 extracellular matrix organization 6.938432e-7
GO:0007618 mating 7.050311e-7
GO:0048522 positive regulation of cellular process 7.160297e-7
GO:0050793 regulation of developmental process 8.862482e-7
GO:0071816 tail-anchored membrane protein insertion into ER membrane 8.876067e-7
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 9.051882e-7
GO:0051336 regulation of hydrolase activity 9.388271e-7
GO:0071840 cellular component organization or biogenesis 9.533934e-7
GO:0051346 negative regulation of hydrolase activity 1.031567e-6
GO:0006958 complement activation, classical pathway 1.077585e-6
GO:0051057 positive regulation of small GTPase mediated signal transduction 1.079804e-6
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 1.129622e-6
GO:0035691 macrophage migration inhibitory factor signaling pathway 1.129622e-6
GO:0007530 sex determination 1.137776e-6
GO:0055093 response to hyperoxia 1.242673e-6
GO:0006873 cellular ion homeostasis 1.299755e-6
GO:0042221 response to chemical stimulus 1.380696e-6
GO:0014805 smooth muscle adaptation 1.459389e-6
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.489550e-6
GO:0055072 iron ion homeostasis 1.549782e-6
GO:0042993 positive regulation of transcription factor import into nucleus 1.602297e-6
GO:0045087 innate immune response 1.621871e-6
GO:0031667 response to nutrient levels 1.790869e-6
GO:0046907 intracellular transport 1.890345e-6
GO:0043305 negative regulation of mast cell degranulation 2.100582e-6
GO:0045080 positive regulation of chemokine biosynthetic process 2.195824e-6
GO:0010669 epithelial structure maintenance 2.297272e-6
GO:0016044 cellular membrane organization 2.323831e-6
GO:0010038 response to metal ion 2.411050e-6
GO:0060627 regulation of vesicle-mediated transport 2.447103e-6
GO:0050878 regulation of body fluid levels 2.472933e-6
GO:0071260 cellular response to mechanical stimulus 2.477408e-6
GO:0042345 regulation of NF-kappaB import into nucleus 2.613868e-6
GO:0002246 wound healing involved in inflammatory response 2.695874e-6
GO:0046579 positive regulation of Ras protein signal transduction 2.699418e-6
GO:0051297 centrosome organization 2.717660e-6
GO:0061024 membrane organization 2.719062e-6
GO:0023051 regulation of signaling 2.853788e-6
GO:0030728 ovulation 3.062554e-6
GO:0022008 neurogenesis 3.075762e-6
GO:0016049 cell growth 3.082127e-6
GO:0002455 humoral immune response mediated by circulating immunoglobulin 3.136307e-6
GO:0030240 skeletal muscle thin filament assembly 3.197183e-6
GO:0044092 negative regulation of molecular function 3.199300e-6
GO:0048699 generation of neurons 3.319744e-6
GO:0007010 cytoskeleton organization 3.517431e-6
GO:0007399 nervous system development 3.711907e-6
GO:0048468 cell development 3.831558e-6
GO:0006886 intracellular protein transport 4.034822e-6
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 4.099665e-6
GO:0042396 phosphagen biosynthetic process 4.099665e-6
GO:0051704 multi-organism process 4.423724e-6
GO:0000086 G2/M transition of mitotic cell cycle 4.581609e-6
GO:0071241 cellular response to inorganic substance 4.617049e-6
GO:0006928 cellular component movement 4.640607e-6
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 4.715987e-6
GO:0002576 platelet degranulation 4.878774e-6
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 5.074592e-6
GO:0006703 estrogen biosynthetic process 5.152145e-6
GO:0050690 regulation of defense response to virus by virus 5.210923e-6
GO:0050756 fractalkine metabolic process 5.383726e-6
GO:0061370 testosterone biosynthetic process 5.383726e-6
GO:0033595 response to genistein 5.383726e-6
GO:0050778 positive regulation of immune response 5.676913e-6
GO:0019226 transmission of nerve impulse 5.859948e-6
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 5.868516e-6
GO:0002922 positive regulation of humoral immune response 6.005314e-6
GO:0060716 labyrinthine layer blood vessel development 6.152789e-6
GO:0048585 negative regulation of response to stimulus 6.219794e-6
GO:0055082 cellular chemical homeostasis 6.350480e-6
GO:0048584 positive regulation of response to stimulus 6.565194e-6
GO:0051960 regulation of nervous system development 6.773298e-6
GO:0048609 multicellular organismal reproductive process 6.839227e-6
GO:0002579 positive regulation of antigen processing and presentation 7.151846e-6
GO:0046314 phosphocreatine biosynthetic process 7.285162e-6
GO:0002697 regulation of immune effector process 7.421382e-6
GO:0030900 forebrain development 7.424292e-6
GO:0060632 regulation of microtubule-based movement 7.684234e-6
GO:0033036 macromolecule localization 8.225387e-6
GO:0035023 regulation of Rho protein signal transduction 8.986710e-6
GO:0051238 sequestering of metal ion 9.119199e-6
GO:0033273 response to vitamin 9.231883e-6
GO:0045655 regulation of monocyte differentiation 9.385507e-6
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion 9.660224e-6
GO:0071258 cellular response to gravity 9.660224e-6
GO:0035491 positive regulation of leukotriene production involved in inflammatory response 9.660224e-6
GO:0061044 negative regulation of vascular wound healing 9.660224e-6
GO:0090023 positive regulation of neutrophil chemotaxis 1.068806e-5
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.119720e-5
GO:0021756 striatum development 1.121837e-5
GO:0014806 smooth muscle hyperplasia 1.133522e-5
GO:0045657 positive regulation of monocyte differentiation 1.147170e-5
GO:0021983 pituitary gland development 1.169943e-5
GO:0001775 cell activation 1.172741e-5
GO:0043068 positive regulation of programmed cell death 1.182184e-5
GO:0010035 response to inorganic substance 1.241986e-5
GO:0010648 negative regulation of cell communication 1.363390e-5
GO:0002886 regulation of myeloid leukocyte mediated immunity 1.380974e-5
GO:0035270 endocrine system development 1.386795e-5
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 1.429838e-5
GO:0031023 microtubule organizing center organization 1.445655e-5
GO:0023057 negative regulation of signaling 1.453844e-5
GO:0009887 organ morphogenesis 1.568565e-5
GO:0046903 secretion 1.593201e-5
GO:0032757 positive regulation of interleukin-8 production 1.613790e-5
GO:0048520 positive regulation of behavior 1.647065e-5
GO:0014912 negative regulation of smooth muscle cell migration 1.721388e-5
GO:0007268 synaptic transmission 1.735897e-5
GO:0060027 convergent extension involved in gastrulation 1.756396e-5
GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S 1.780773e-5
GO:0090222 centrosome-templated microtubule nucleation 1.801105e-5
GO:0072376 protein activation cascade 1.804108e-5
GO:0001893 maternal placenta development 1.820078e-5
GO:0042990 regulation of transcription factor import into nucleus 1.844697e-5
GO:0010226 response to lithium ion 1.886400e-5
GO:0002673 regulation of acute inflammatory response 1.919305e-5
GO:0050688 regulation of defense response to virus 1.950300e-5
GO:0007249 I-kappaB kinase/NF-kappaB cascade 2.010795e-5
GO:2000097 regulation of smooth muscle cell-matrix adhesion 2.022702e-5
GO:0042058 regulation of epidermal growth factor receptor signaling pathway 2.022729e-5
GO:0055002 striated muscle cell development 2.087809e-5
GO:0045785 positive regulation of cell adhesion 2.180612e-5
GO:0010646 regulation of cell communication 2.249634e-5
GO:0046889 positive regulation of lipid biosynthetic process 2.262968e-5
GO:0042940 D-amino acid transport 2.305311e-5
GO:0007267 cell-cell signaling 2.403747e-5
GO:0021536 diencephalon development 2.453087e-5
GO:0051938 L-glutamate import 2.539318e-5
GO:0030834 regulation of actin filament depolymerization 2.572110e-5
GO:0002819 regulation of adaptive immune response 2.592763e-5
GO:0031214 biomineral tissue development 2.605422e-5
GO:0010466 negative regulation of peptidase activity 2.608690e-5
GO:0006880 intracellular sequestering of iron ion 2.622921e-5
GO:0007565 female pregnancy 2.769035e-5
GO:0048519 negative regulation of biological process 2.773434e-5
GO:0006897 endocytosis 2.823698e-5
GO:0007015 actin filament organization 2.830702e-5
GO:0022600 digestive system process 2.885220e-5
GO:0051693 actin filament capping 2.923726e-5
GO:0030835 negative regulation of actin filament depolymerization 2.969420e-5
GO:0010942 positive regulation of cell death 2.977397e-5
GO:0007620 copulation 3.100683e-5
GO:0051345 positive regulation of hydrolase activity 3.205982e-5
GO:0000041 transition metal ion transport 3.330221e-5
GO:0034097 response to cytokine stimulus 3.389286e-5
GO:0009894 regulation of catabolic process 3.437607e-5
GO:0030878 thyroid gland development 3.469627e-5
GO:0044060 regulation of endocrine process 3.474311e-5
GO:0045651 positive regulation of macrophage differentiation 3.504492e-5
GO:0050921 positive regulation of chemotaxis 3.800984e-5
GO:0072507 divalent inorganic cation homeostasis 3.802416e-5
GO:0006826 iron ion transport 3.822792e-5
GO:0021544 subpallium development 3.950811e-5
GO:0007589 body fluid secretion 4.093323e-5
GO:0032764 negative regulation of mast cell cytokine production 4.158640e-5
GO:0032879 regulation of localization 4.279527e-5
GO:0045073 regulation of chemokine biosynthetic process 4.284403e-5
GO:0050801 ion homeostasis 4.296428e-5
GO:0030100 regulation of endocytosis 4.449693e-5
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 4.466782e-5
GO:0034764 positive regulation of transmembrane transport 4.553056e-5
GO:0051247 positive regulation of protein metabolic process 4.814848e-5
GO:0022414 reproductive process 4.820957e-5
GO:0055067 monovalent inorganic cation homeostasis 4.846294e-5
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 4.920350e-5
GO:0048871 multicellular organismal homeostasis 5.002669e-5
GO:0007635 chemosensory behavior 5.024925e-5
GO:0002682 regulation of immune system process 5.029004e-5
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 5.037620e-5
GO:0002685 regulation of leukocyte migration 5.157464e-5
GO:0010193 response to ozone 5.240162e-5
GO:0051049 regulation of transport 5.266832e-5
GO:0070741 response to interleukin-6 5.280959e-5
GO:0060611 mammary gland fat development 5.433505e-5
GO:0070727 cellular macromolecule localization 5.566497e-5
GO:0009966 regulation of signal transduction 5.637093e-5
GO:0006778 porphyrin-containing compound metabolic process 5.640064e-5
GO:0042167 heme catabolic process 5.738322e-5
GO:0048666 neuron development 5.855543e-5
GO:0072503 cellular divalent inorganic cation homeostasis 5.874911e-5
GO:0043462 regulation of ATPase activity 5.880560e-5
GO:0033687 osteoblast proliferation 5.939781e-5
GO:0000003 reproduction 5.982540e-5
GO:0019725 cellular homeostasis 6.460667e-5
GO:0002830 positive regulation of type 2 immune response 6.577129e-5
GO:0010811 positive regulation of cell-substrate adhesion 6.673968e-5
GO:0042488 positive regulation of odontogenesis of dentine-containing tooth 6.721954e-5
GO:0033121 regulation of purine nucleotide catabolic process 6.875757e-5
GO:0010033 response to organic substance 7.141180e-5
GO:0090022 regulation of neutrophil chemotaxis 7.240942e-5
GO:0032971 regulation of muscle filament sliding 7.244215e-5
GO:0034613 cellular protein localization 7.309839e-5
GO:0032496 response to lipopolysaccharide 7.335125e-5
GO:0009607 response to biotic stimulus 7.336304e-5
GO:0043085 positive regulation of catalytic activity 7.343941e-5
GO:0007243 intracellular protein kinase cascade 7.410135e-5
GO:0033013 tetrapyrrole metabolic process 7.494787e-5
GO:0009296 flagellum assembly 7.606723e-5
GO:0001300 chronological cell aging 7.821422e-5
GO:0016064 immunoglobulin mediated immune response 7.954355e-5
GO:0048878 chemical homeostasis 7.977688e-5
GO:0043065 positive regulation of apoptosis 8.158919e-5
GO:0002237 response to molecule of bacterial origin 8.246233e-5
GO:0055001 muscle cell development 8.493240e-5
GO:0015810 aspartate transport 8.493515e-5
GO:0031329 regulation of cellular catabolic process 8.580181e-5
GO:0031657 regulation of cyclin-dependent protein kinase activity involved in G1/S 8.701433e-5
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter 8.833214e-5
GO:0009115 xanthine catabolic process 8.833418e-5
GO:0030194 positive regulation of blood coagulation 9.047403e-5
GO:0033617 mitochondrial respiratory chain complex IV assembly 9.301475e-5
GO:0006746 FADH2 metabolic process 9.301475e-5
GO:0032425 positive regulation of mismatch repair 9.767149e-5
GO:0046651 lymphocyte proliferation 9.819214e-5
GO:0032722 positive regulation of chemokine production 9.905757e-5
GO:0045089 positive regulation of innate immune response 1.006091e-4
GO:0050764 regulation of phagocytosis 1.028537e-4
GO:0071731 response to nitric oxide 1.064843e-4
GO:0050920 regulation of chemotaxis 1.089339e-4
GO:0051764 actin crosslink formation 1.095416e-4
GO:0001660 fever generation 1.110521e-4
GO:0070779 D-aspartate import 1.127084e-4
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.139943e-4
GO:0051707 response to other organism 1.168989e-4
GO:0045738 negative regulation of DNA repair 1.169835e-4
GO:0050790 regulation of catalytic activity 1.237973e-4
GO:0032677 regulation of interleukin-8 production 1.248996e-4
GO:0002699 positive regulation of immune effector process 1.274266e-4
GO:0090084 negative regulation of inclusion body assembly 1.290633e-4
GO:0052547 regulation of peptidase activity 1.297332e-4
GO:0019724 B cell mediated immunity 1.305662e-4
GO:0048278 vesicle docking 1.372583e-4
GO:2001020 regulation of response to DNA damage stimulus 1.385315e-4
GO:0015031 protein transport 1.389556e-4
GO:0051222 positive regulation of protein transport 1.392721e-4
GO:0006885 regulation of pH 1.413983e-4
GO:0007599 hemostasis 1.419232e-4
GO:0001542 ovulation from ovarian follicle 1.424268e-4
GO:0030182 neuron differentiation 1.443262e-4
GO:0009968 negative regulation of signal transduction 1.453669e-4
GO:0043217 myelin maintenance 1.478178e-4
GO:0048646 anatomical structure formation involved in morphogenesis 1.553207e-4
GO:0071842 cellular component organization at cellular level 1.604577e-4
GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway 1.610848e-4
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.617354e-4
GO:0045059 positive thymic T cell selection 1.637719e-4
GO:0032386 regulation of intracellular transport 1.648045e-4
GO:0048011 nerve growth factor receptor signaling pathway 1.710677e-4
GO:0043030 regulation of macrophage activation 1.718710e-4
GO:0006887 exocytosis 1.747819e-4
GO:0044245 polysaccharide digestion 1.751229e-4
GO:0051298 centrosome duplication 1.801236e-4
GO:0010740 positive regulation of intracellular protein kinase cascade 1.809836e-4
GO:0006357 regulation of transcription from RNA polymerase II promoter 1.863824e-4
GO:0044258 intestinal lipid catabolic process 1.865208e-4
GO:0018350 protein esterification 1.865208e-4
GO:0007041 lysosomal transport 1.872579e-4
GO:0042663 regulation of endodermal cell fate specification 1.925479e-4
GO:0048266 behavioral response to pain 1.937535e-4
GO:0030193 regulation of blood coagulation 1.992156e-4
GO:0008104 protein localization 1.996974e-4
GO:0051128 regulation of cellular component organization 2.006938e-4
GO:0005993 trehalose catabolic process 2.023048e-4
GO:0043060 meiotic metaphase I plate congression 2.059308e-4
GO:0002920 regulation of humoral immune response 2.141817e-4
GO:0009629 response to gravity 2.157262e-4
GO:0002690 positive regulation of leukocyte chemotaxis 2.177312e-4
GO:0050820 positive regulation of coagulation 2.187412e-4
GO:0015849 organic acid transport 2.222578e-4
GO:0060907 positive regulation of macrophage cytokine production 2.279193e-4
GO:0001504 neurotransmitter uptake 2.306112e-4
GO:0051930 regulation of sensory perception of pain 2.309354e-4
GO:0051146 striated muscle cell differentiation 2.341749e-4
GO:0045184 establishment of protein localization 2.346607e-4
GO:0032943 mononuclear cell proliferation 2.360933e-4
GO:0045070 positive regulation of viral genome replication 2.366867e-4
GO:0007596 blood coagulation 2.386709e-4
GO:0006828 manganese ion transport 2.411687e-4
GO:0014047 glutamate secretion 2.528845e-4
GO:0046942 carboxylic acid transport 2.618700e-4
GO:0009826 unidimensional cell growth 2.624070e-4
GO:0030216 keratinocyte differentiation 2.638982e-4
GO:0010867 positive regulation of triglyceride biosynthetic process 2.642091e-4
GO:0060879 semicircular canal fusion 2.674350e-4
GO:0070352 positive regulation of white fat cell proliferation 2.674350e-4
GO:0060661 submandibular salivary gland formation 2.674350e-4
GO:0061115 lung proximal/distal axis specification 2.674350e-4
GO:0050674 urothelial cell proliferation 2.674350e-4
GO:0060496 mesenchymal-epithelial cell signaling involved in lung development 2.674350e-4
GO:0050677 positive regulation of urothelial cell proliferation 2.674350e-4
GO:0060436 bronchiole morphogenesis 2.674350e-4
GO:0006874 cellular calcium ion homeostasis 2.719489e-4
GO:0042137 sequestering of neurotransmitter 2.726172e-4
GO:0070668 positive regulation of mast cell proliferation 2.800087e-4
GO:0002502 peptide antigen assembly with MHC class I protein complex 2.800175e-4
GO:0034454 microtubule anchoring at centrosome 2.867268e-4
GO:0070661 leukocyte proliferation 2.886204e-4
GO:0007286 spermatid development 3.009287e-4
GO:0050776 regulation of immune response 3.230305e-4
GO:0031424 keratinization 3.255321e-4
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 3.255851e-4
GO:0061041 regulation of wound healing 3.299098e-4
GO:0018904 organic ether metabolic process 3.300897e-4
GO:0050877 neurological system process 3.320023e-4
GO:0018894 dibenzo-p-dioxin metabolic process 3.361660e-4
GO:0002718 regulation of cytokine production involved in immune response 3.368169e-4
GO:0033025 regulation of mast cell apoptosis 3.406444e-4
GO:0032989 cellular component morphogenesis 3.541361e-4
GO:0002577 regulation of antigen processing and presentation 3.549044e-4
GO:0007017 microtubule-based process 3.582328e-4
GO:0032320 positive regulation of Ras GTPase activity 3.754043e-4
GO:0003018 vascular process in circulatory system 3.806045e-4
GO:0071841 cellular component organization or biogenesis at cellular level 3.842409e-4
GO:0051918 negative regulation of fibrinolysis 3.865086e-4
GO:0002687 positive regulation of leukocyte migration 3.911732e-4
GO:0052548 regulation of endopeptidase activity 3.971224e-4
GO:0048523 negative regulation of cellular process 4.081441e-4
GO:0000132 establishment of mitotic spindle orientation 4.082310e-4
GO:0048515 spermatid differentiation 4.102174e-4
GO:0006904 vesicle docking involved in exocytosis 4.250082e-4
GO:0044093 positive regulation of molecular function 4.440051e-4
GO:0030030 cell projection organization 4.461527e-4
GO:0051409 response to nitrosative stress 4.485046e-4
GO:0002260 lymphocyte homeostasis 4.576466e-4
GO:0001776 leukocyte homeostasis 4.612290e-4
GO:0009744 response to sucrose stimulus 4.624504e-4
GO:0031958 corticosteroid receptor signaling pathway 4.643754e-4
GO:0032741 positive regulation of interleukin-18 production 4.651797e-4
GO:0048667 cell morphogenesis involved in neuron differentiation 4.686587e-4
GO:0007420 brain development 4.690757e-4
GO:0007409 axonogenesis 4.726778e-4
GO:0048146 positive regulation of fibroblast proliferation 4.732525e-4
GO:0002684 positive regulation of immune system process 4.763233e-4
GO:0048812 neuron projection morphogenesis 4.767080e-4
GO:0022406 membrane docking 4.813772e-4
GO:0051329 interphase of mitotic cell cycle 4.837522e-4
GO:0019884 antigen processing and presentation of exogenous antigen 4.888610e-4
GO:0070372 regulation of ERK1 and ERK2 cascade 4.907791e-4
GO:0050880 regulation of blood vessel size 4.914410e-4
GO:0030837 negative regulation of actin filament polymerization 5.050907e-4
GO:0060136 embryonic process involved in female pregnancy 5.134303e-4
GO:0009725 response to hormone stimulus 5.158981e-4
GO:0006140 regulation of nucleotide metabolic process 5.229148e-4
GO:0048872 homeostasis of number of cells 5.286999e-4
GO:0006892 post-Golgi vesicle-mediated transport 5.430934e-4
GO:0055074 calcium ion homeostasis 5.460665e-4
GO:0001894 tissue homeostasis 5.509344e-4
GO:0002889 regulation of immunoglobulin mediated immune response 5.667921e-4
GO:0040001 establishment of mitotic spindle localization 5.770596e-4
GO:0035150 regulation of tube size 5.827471e-4
GO:0007042 lysosomal lumen acidification 5.910852e-4
GO:2000036 regulation of stem cell maintenance 6.286125e-4
GO:0050795 regulation of behavior 6.397403e-4
GO:0090066 regulation of anatomical structure size 6.403806e-4
GO:0030316 osteoclast differentiation 6.439613e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0050896 response to stimulus 2.180054e-20
GO:0065008 regulation of biological quality 7.733806e-14
GO:0045672 positive regulation of osteoclast differentiation 2.133927e-13
GO:0051716 cellular response to stimulus 3.180201e-13
GO:0007154 cell communication 4.204435e-13
GO:0042221 response to chemical stimulus 5.155989e-13
GO:0065007 biological regulation 8.525925e-13
GO:0023052 signaling 9.494822e-13
GO:0048731 system development 1.131597e-12
GO:0045639 positive regulation of myeloid cell differentiation 1.659360e-12
GO:0048856 anatomical structure development 7.855710e-12
GO:0032501 multicellular organismal process 8.213241e-12
GO:0015670 carbon dioxide transport 1.050291e-11
GO:0048513 organ development 1.416918e-11
GO:0015669 gas transport 2.733261e-11
GO:0007165 signal transduction 4.267097e-11
GO:0045124 regulation of bone resorption 7.889494e-11
GO:0002763 positive regulation of myeloid leukocyte differentiation 8.195651e-11
GO:0003008 system process 9.682123e-11
GO:0034103 regulation of tissue remodeling 1.499002e-10
GO:0046850 regulation of bone remodeling 2.003878e-10
GO:0072595 maintenance of protein localization to organelle 2.214113e-10
GO:0010035 response to inorganic substance 2.547645e-10
GO:0051457 maintenance of protein location in nucleus 3.078181e-10
GO:0032849 positive regulation of cellular pH reduction 4.332665e-10
GO:0043503 skeletal muscle fiber adaptation 4.717077e-10
GO:0007275 multicellular organismal development 4.808999e-10
GO:0006950 response to stress 5.028979e-10
GO:0002682 regulation of immune system process 7.137731e-10
GO:0030097 hemopoiesis 1.090379e-9
GO:0050789 regulation of biological process 1.116101e-9
GO:0042592 homeostatic process 1.291841e-9
GO:0048534 hemopoietic or lymphoid organ development 2.703289e-9
GO:0045780 positive regulation of bone resorption 3.411995e-9
GO:0060013 righting reflex 6.828137e-9
GO:0010038 response to metal ion 7.244951e-9
GO:0014866 skeletal myofibril assembly 7.251738e-9
GO:0032502 developmental process 7.823341e-9
GO:0040032 post-embryonic body morphogenesis 8.622194e-9
GO:0055001 muscle cell development 1.000351e-8
GO:0002520 immune system development 1.293141e-8
GO:0060004 reflex 1.444480e-8
GO:0034105 positive regulation of tissue remodeling 1.975411e-8
GO:2000249 regulation of actin cytoskeleton reorganization 2.363743e-8
GO:0002376 immune system process 2.388668e-8
GO:0045637 regulation of myeloid cell differentiation 2.454618e-8
GO:0050907 detection of chemical stimulus involved in sensory perception 2.494376e-8
GO:0007606 sensory perception of chemical stimulus 3.076005e-8
GO:0051239 regulation of multicellular organismal process 3.533769e-8
GO:0051023 regulation of immunoglobulin secretion 4.577528e-8
GO:0050877 neurological system process 4.962379e-8
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 5.693553e-8
GO:0030240 skeletal muscle thin filament assembly 9.032812e-8
GO:0040007 growth 1.012477e-7
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 1.059784e-7
GO:0046967 cytosol to ER transport 1.437164e-7
GO:0019060 intracellular transport of viral proteins in host cell 1.437164e-7
GO:0050794 regulation of cellular process 1.486403e-7
GO:0001894 tissue homeostasis 1.758345e-7
GO:0032507 maintenance of protein location in cell 2.124314e-7
GO:0021758 putamen development 2.698932e-7
GO:0021757 caudate nucleus development 2.698932e-7
GO:0003012 muscle system process 3.727041e-7
GO:0060292 long term synaptic depression 3.836210e-7
GO:0050801 ion homeostasis 3.920209e-7
GO:0032847 regulation of cellular pH reduction 4.123597e-7
GO:0046649 lymphocyte activation 5.119882e-7
GO:0015980 energy derivation by oxidation of organic compounds 5.675918e-7
GO:0002064 epithelial cell development 5.827620e-7
GO:0070887 cellular response to chemical stimulus 6.466098e-7
GO:0019725 cellular homeostasis 6.562034e-7
GO:2000351 regulation of endothelial cell apoptosis 7.371189e-7
GO:0007423 sensory organ development 7.559504e-7
GO:0055013 cardiac muscle cell development 8.268988e-7
GO:0030239 myofibril assembly 8.917367e-7
GO:0090183 regulation of kidney development 9.764741e-7
GO:0042573 retinoic acid metabolic process 1.052781e-6
GO:0009404 toxin metabolic process 1.187465e-6
GO:0009886 post-embryonic morphogenesis 1.251306e-6
GO:0009593 detection of chemical stimulus 1.279201e-6
GO:0006730 one-carbon metabolic process 1.296197e-6
GO:0050906 detection of stimulus involved in sensory perception 1.464823e-6
GO:0048878 chemical homeostasis 1.581118e-6
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 1.919267e-6
GO:0034614 cellular response to reactive oxygen species 1.921735e-6
GO:0007186 G-protein coupled receptor protein signaling pathway 1.967959e-6
GO:0051235 maintenance of location 1.995685e-6
GO:0051651 maintenance of location in cell 2.053085e-6
GO:0045185 maintenance of protein location 2.198920e-6
GO:0055006 cardiac cell development 2.252621e-6
GO:0051146 striated muscle cell differentiation 2.334388e-6
GO:0072273 metanephric nephron morphogenesis 2.392072e-6
GO:0001833 inner cell mass cell proliferation 2.395085e-6
GO:2000353 positive regulation of endothelial cell apoptosis 2.675346e-6
GO:0070301 cellular response to hydrogen peroxide 2.728743e-6
GO:0031032 actomyosin structure organization 2.979758e-6
GO:0042692 muscle cell differentiation 3.117547e-6
GO:2000027 regulation of organ morphogenesis 3.119149e-6
GO:0000302 response to reactive oxygen species 3.416556e-6
GO:0048871 multicellular organismal homeostasis 3.578636e-6
GO:0006112 energy reserve metabolic process 3.850279e-6
GO:0045722 positive regulation of gluconeogenesis 4.073883e-6
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 4.235462e-6
GO:0006873 cellular ion homeostasis 4.281359e-6
GO:0048869 cellular developmental process 4.589314e-6
GO:0045321 leukocyte activation 4.624807e-6
GO:0001832 blastocyst growth 4.838594e-6
GO:0034653 retinoic acid catabolic process 5.286416e-6
GO:0010033 response to organic substance 5.332634e-6
GO:0072088 nephron epithelium morphogenesis 5.373721e-6
GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 5.635365e-6
GO:0055002 striated muscle cell development 5.886027e-6
GO:0014706 striated muscle tissue development 6.355907e-6
GO:0060249 anatomical structure homeostasis 6.556980e-6
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 6.685242e-6
GO:0071874 cellular response to norepinephrine stimulus 7.490117e-6
GO:0042475 odontogenesis of dentine-containing tooth 8.335936e-6
GO:0002761 regulation of myeloid leukocyte differentiation 8.359817e-6
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 8.564657e-6
GO:0030154 cell differentiation 8.777529e-6
GO:0032414 positive regulation of ion transmembrane transporter activity 8.841650e-6
GO:0055082 cellular chemical homeostasis 8.940163e-6
GO:0006936 muscle contraction 9.434130e-6
GO:0032853 positive regulation of Ran GTPase activity 9.738068e-6
GO:0009229 thiamine diphosphate biosynthetic process 9.738068e-6
GO:0072040 negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis 1.018275e-5
GO:0051939 gamma-aminobutyric acid import 1.067136e-5
GO:0031124 mRNA 3'-end processing 1.142390e-5
GO:0032259 methylation 1.192068e-5
GO:0050793 regulation of developmental process 1.261970e-5
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 1.285807e-5
GO:0072289 metanephric nephron tubule formation 1.328382e-5
GO:0031123 RNA 3'-end processing 1.359440e-5
GO:0006776 vitamin A metabolic process 1.461239e-5
GO:0048747 muscle fiber development 1.467332e-5
GO:0072077 renal vesicle morphogenesis 1.569841e-5
GO:0051240 positive regulation of multicellular organismal process 1.770352e-5
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 1.800598e-5
GO:0043501 skeletal muscle adaptation 1.847610e-5
GO:0035264 multicellular organism growth 2.208235e-5
GO:0010715 regulation of extracellular matrix disassembly 2.218879e-5
GO:0007600 sensory perception 2.224636e-5
GO:0042110 T cell activation 2.432724e-5
GO:0017085 response to insecticide 2.464516e-5
GO:0001778 plasma membrane repair 2.521164e-5
GO:0043010 camera-type eye development 2.548543e-5
GO:0051179 localization 2.729290e-5
GO:0048741 skeletal muscle fiber development 2.809730e-5
GO:0001508 regulation of action potential 2.864710e-5
GO:0003382 epithelial cell morphogenesis 2.875395e-5
GO:0009719 response to endogenous stimulus 2.895714e-5
GO:0009611 response to wounding 3.270551e-5
GO:0042402 cellular biogenic amine catabolic process 3.331512e-5
GO:0050776 regulation of immune response 3.395374e-5
GO:0019226 transmission of nerve impulse 3.667627e-5
GO:0060347 heart trabecula formation 3.671356e-5
GO:0007166 cell surface receptor linked signaling pathway 3.679370e-5
GO:0060537 muscle tissue development 3.737654e-5
GO:0001654 eye development 4.003162e-5
GO:0045589 regulation of regulatory T cell differentiation 4.045776e-5
GO:0006979 response to oxidative stress 4.277425e-5
GO:0045670 regulation of osteoclast differentiation 4.336495e-5
GO:0051606 detection of stimulus 4.400003e-5
GO:0042363 fat-soluble vitamin catabolic process 4.614641e-5
GO:0070371 ERK1 and ERK2 cascade 4.626679e-5
GO:0010259 multicellular organismal aging 4.776292e-5
GO:0002521 leukocyte differentiation 4.811109e-5
GO:0009628 response to abiotic stimulus 4.845638e-5
GO:0072028 nephron morphogenesis 4.877221e-5
GO:0019362 pyridine nucleotide metabolic process 4.914598e-5
GO:0006970 response to osmotic stress 4.930971e-5
GO:0046037 GMP metabolic process 5.230281e-5
GO:0002637 regulation of immunoglobulin production 5.231260e-5
GO:0009791 post-embryonic development 5.554482e-5
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity 5.714337e-5
GO:0055003 cardiac myofibril assembly 5.976417e-5
GO:0072282 metanephric nephron tubule morphogenesis 6.111671e-5
GO:0010735 positive regulation of transcription via serum response element binding 6.174001e-5
GO:0072215 regulation of metanephros development 6.700018e-5
GO:0007608 sensory perception of smell 6.739829e-5
GO:0001823 mesonephros development 6.809864e-5
GO:0009605 response to external stimulus 6.825835e-5
GO:0007399 nervous system development 6.865504e-5
GO:0001783 B cell apoptosis 7.091775e-5
GO:0014816 satellite cell differentiation 7.347461e-5
GO:0002312 B cell activation involved in immune response 7.649808e-5
GO:0055080 cation homeostasis 7.722071e-5
GO:0051234 establishment of localization 7.744283e-5
GO:0019556 histidine catabolic process to glutamate and formamide 7.797212e-5
GO:0006378 mRNA polyadenylation 7.833450e-5
GO:0001523 retinoid metabolic process 8.142228e-5
GO:0032088 negative regulation of NF-kappaB transcription factor activity 8.576845e-5
GO:0018345 protein palmitoylation 8.599839e-5
GO:0009887 organ morphogenesis 8.661498e-5
GO:0034599 cellular response to oxidative stress 9.003672e-5
GO:0043269 regulation of ion transport 9.478689e-5
GO:0045348 positive regulation of MHC class II biosynthetic process 9.701027e-5
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 1.000304e-4
GO:0030048 actin filament-based movement 1.046195e-4
GO:0048754 branching morphogenesis of a tube 1.057098e-4
GO:0051056 regulation of small GTPase mediated signal transduction 1.078779e-4
GO:0002709 regulation of T cell mediated immunity 1.125608e-4
GO:0051704 multi-organism process 1.141942e-4
GO:0048518 positive regulation of biological process 1.147775e-4
GO:0072210 metanephric nephron development 1.153671e-4
GO:0009725 response to hormone stimulus 1.159078e-4
GO:0043067 regulation of programmed cell death 1.159422e-4
GO:0046653 tetrahydrofolate metabolic process 1.206170e-4
GO:0019441 tryptophan catabolic process to kynurenine 1.207788e-4
GO:0009888 tissue development 1.215458e-4
GO:0060231 mesenchymal to epithelial transition 1.219816e-4
GO:0042743 hydrogen peroxide metabolic process 1.240884e-4
GO:0046483 heterocycle metabolic process 1.255086e-4
GO:0042297 vocal learning 1.317753e-4
GO:0046496 nicotinamide nucleotide metabolic process 1.319548e-4
GO:0002837 regulation of immune response to tumor cell 1.323385e-4
GO:0072283 metanephric renal vesicle morphogenesis 1.326987e-4
GO:0080164 regulation of nitric oxide metabolic process 1.329392e-4
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 1.366772e-4
GO:0051252 regulation of RNA metabolic process 1.423312e-4
GO:0002318 myeloid progenitor cell differentiation 1.427971e-4
GO:0045590 negative regulation of regulatory T cell differentiation 1.440732e-4
GO:0042060 wound healing 1.446284e-4
GO:0001824 blastocyst development 1.451560e-4
GO:0042744 hydrogen peroxide catabolic process 1.513246e-4
GO:0031334 positive regulation of protein complex assembly 1.594411e-4
GO:0061061 muscle structure development 1.639889e-4
GO:0071870 cellular response to catecholamine stimulus 1.664539e-4
GO:0035590 purinergic nucleotide receptor signaling pathway 1.672108e-4
GO:0042445 hormone metabolic process 1.674617e-4
GO:0046684 response to pyrethroid 1.696432e-4
GO:0022600 digestive system process 1.701760e-4
GO:0007610 behavior 1.710899e-4
GO:0072592 oxygen metabolic process 1.749602e-4
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 1.749602e-4
GO:2000026 regulation of multicellular organismal development 1.785332e-4
GO:0003338 metanephros morphogenesis 1.797391e-4
GO:0035051 cardiac cell differentiation 1.815100e-4
GO:0072034 renal vesicle induction 1.821401e-4
GO:0045764 positive regulation of cellular amino acid metabolic process 1.902655e-4
GO:0043092 L-amino acid import 1.943434e-4
GO:0010043 response to zinc ion 1.954119e-4
GO:0050808 synapse organization 1.957824e-4
GO:0055007 cardiac muscle cell differentiation 1.967106e-4
GO:0042981 regulation of apoptosis 1.988778e-4
GO:0030098 lymphocyte differentiation 2.033398e-4
GO:0009743 response to carbohydrate stimulus 2.055609e-4
GO:0035247 peptidyl-arginine omega-N-methylation 2.102501e-4
GO:0060005 vestibular reflex 2.105106e-4
GO:0010225 response to UV-C 2.132004e-4
GO:0007009 plasma membrane organization 2.162812e-4
GO:0002026 regulation of the force of heart contraction 2.164434e-4
GO:0002839 positive regulation of immune response to tumor cell 2.267842e-4
GO:0002833 positive regulation of response to biotic stimulus 2.323249e-4
GO:0018094 protein polyglycylation 2.369434e-4
GO:0001887 selenium compound metabolic process 2.369434e-4
GO:0043462 regulation of ATPase activity 2.378664e-4
GO:0019439 aromatic compound catabolic process 2.382424e-4
GO:0060047 heart contraction 2.403182e-4
GO:0051024 positive regulation of immunoglobulin secretion 2.406128e-4
GO:0007601 visual perception 2.409822e-4
GO:0006805 xenobiotic metabolic process 2.468430e-4
GO:0030818 negative regulation of cAMP biosynthetic process 2.539676e-4
GO:0022603 regulation of anatomical structure morphogenesis 2.557069e-4
GO:0048738 cardiac muscle tissue development 2.578459e-4
GO:0072087 renal vesicle development 2.590092e-4
GO:0001775 cell activation 2.678347e-4
GO:0035886 vascular smooth muscle cell differentiation 2.720293e-4
GO:0018364 peptidyl-glutamine methylation 2.840394e-4
GO:0009612 response to mechanical stimulus 2.861584e-4
GO:0030099 myeloid cell differentiation 2.886202e-4
GO:0070995 NADPH oxidation 2.926647e-4
GO:0019227 neuronal action potential propagation 2.965554e-4
GO:0097035 regulation of membrane lipid distribution 2.965554e-4
GO:0032411 positive regulation of transporter activity 2.965803e-4
GO:0009410 response to xenobiotic stimulus 2.994417e-4
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 3.084981e-4
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation 3.144096e-4
GO:0048489 synaptic vesicle transport 3.212368e-4
GO:0016101 diterpenoid metabolic process 3.220650e-4
GO:0021658 rhombomere 3 morphogenesis 3.261587e-4
GO:0019228 regulation of action potential in neuron 3.401663e-4
GO:0008366 axon ensheathment 3.407527e-4
GO:0050953 sensory perception of light stimulus 3.517599e-4
GO:0021544 subpallium development 3.522675e-4
GO:0043631 RNA polyadenylation 3.562615e-4
GO:0030003 cellular cation homeostasis 3.610154e-4
GO:0006479 protein methylation 3.678809e-4
GO:0042542 response to hydrogen peroxide 3.688063e-4
GO:0006810 transport 3.783853e-4
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 3.926163e-4
GO:0050778 positive regulation of immune response 3.927584e-4
GO:0009749 response to glucose stimulus 3.964095e-4
GO:0072078 nephron tubule morphogenesis 3.992572e-4
GO:0002684 positive regulation of immune system process 4.025893e-4
GO:0042098 T cell proliferation 4.045332e-4
GO:0031943 regulation of glucocorticoid metabolic process 4.059582e-4
GO:0070189 kynurenine metabolic process 4.069252e-4
GO:0042552 myelination 4.081666e-4
GO:0007565 female pregnancy 4.086125e-4
GO:0048469 cell maturation 4.157330e-4
GO:0000041 transition metal ion transport 4.265243e-4
GO:0042551 neuron maturation 4.310494e-4
GO:0008356 asymmetric cell division 4.320657e-4
GO:0071310 cellular response to organic substance 4.462121e-4
GO:0006420 arginyl-tRNA aminoacylation 4.463834e-4
GO:0034284 response to monosaccharide stimulus 4.470110e-4
GO:0010556 regulation of macromolecule biosynthetic process 4.632854e-4
GO:0010468 regulation of gene expression 4.661652e-4
GO:0070555 response to interleukin-1 4.685290e-4
GO:0006355 regulation of transcription, DNA-dependent 4.692768e-4
GO:0048545 response to steroid hormone stimulus 4.791752e-4
GO:0031946 regulation of glucocorticoid biosynthetic process 4.821954e-4
GO:0048793 pronephros development 4.821954e-4
GO:0010949 negative regulation of intestinal phytosterol absorption 4.831600e-4
GO:0045796 negative regulation of intestinal cholesterol absorption 4.831600e-4
GO:0003278 apoptosis involved in heart morphogenesis 4.831600e-4
GO:0010226 response to lithium ion 4.955587e-4
GO:0071320 cellular response to cAMP 5.151982e-4
GO:0045851 pH reduction 5.226356e-4
GO:0072001 renal system development 5.306736e-4
GO:0051171 regulation of nitrogen compound metabolic process 5.463151e-4
GO:0043497 regulation of protein heterodimerization activity 5.504869e-4
GO:0009636 response to toxin 5.855471e-4
GO:0016049 cell growth 5.915107e-4
GO:0055017 cardiac muscle tissue growth 5.920251e-4
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 6.038595e-4
GO:0051977 lysophospholipid transport 6.038595e-4
GO:0001966 thigmotaxis 6.038595e-4
GO:0007630 jump response 6.038595e-4
GO:0070925 organelle assembly 6.204776e-4
GO:2000145 regulation of cell motility 6.398215e-4
GO:0043090 amino acid import 6.434565e-4
GO:0030316 osteoclast differentiation 6.691234e-4
GO:0010172 embryonic body morphogenesis 6.704117e-4
GO:0071347 cellular response to interleukin-1 6.857973e-4
GO:0061036 positive regulation of cartilage development 6.900310e-4
GO:0030855 epithelial cell differentiation 6.909398e-4
GO:0072182 regulation of nephron tubule epithelial cell differentiation 7.106717e-4
GO:0009161 ribonucleoside monophosphate metabolic process 7.240734e-4
GO:0031223 auditory behavior 7.329448e-4
GO:0043500 muscle adaptation 7.641954e-4
GO:0051452 intracellular pH reduction 7.746127e-4
GO:0003334 keratinocyte development 7.764818e-4
GO:0090096 positive regulation of metanephric cap mesenchymal cell proliferation 7.779965e-4
GO:0032861 activation of Rap GTPase activity 7.779965e-4
GO:0090346 cellular organofluorine metabolic process 7.794041e-4
GO:0043602 nitrate catabolic process 7.794041e-4
GO:0046210 nitric oxide catabolic process 7.794041e-4
GO:0071670 smooth muscle cell chemotaxis 7.959377e-4
GO:0060981 cell migration involved in coronary angiogenesis 7.959377e-4
GO:0006772 thiamine metabolic process 7.959377e-4
GO:0051725 protein de-ADP-ribosylation 7.959377e-4
GO:0060554 induction of necroptosis of activated-T cells 7.959377e-4
GO:0032229 negative regulation of synaptic transmission, GABAergic 7.978162e-4
GO:0010941 regulation of cell death 8.171200e-4
GO:0006390 transcription from mitochondrial promoter 8.316448e-4
GO:0061384 heart trabecular morphogenesis 8.332726e-4
GO:0045980 negative regulation of nucleotide metabolic process 8.332726e-4
GO:0021756 striatum development 8.463175e-4
GO:0009123 nucleoside monophosphate metabolic process 8.531660e-4
GO:0043583 ear development 8.681507e-4
GO:0006111 regulation of gluconeogenesis 8.693155e-4
GO:0072079 nephron tubule formation 8.693155e-4
GO:0035587 purinergic receptor signaling pathway 8.958406e-4
GO:0071322 cellular response to carbohydrate stimulus 8.960313e-4
GO:0035855 megakaryocyte development 9.048506e-4
GO:0030334 regulation of cell migration 9.138276e-4
GO:0043414 macromolecule methylation 9.554881e-4
GO:0035588 G-protein coupled purinergic receptor signaling pathway 9.570349e-4
GO:0006568 tryptophan metabolic process 9.599004e-4
GO:0032989 cellular component morphogenesis 9.619214e-4
GO:0051591 response to cAMP 9.619972e-4
GO:0019219 regulation of nucleobase-containing compound metabolic process 9.627280e-4
GO:0006775 fat-soluble vitamin metabolic process 9.672816e-4
GO:0006721 terpenoid metabolic process 9.950185e-4
GO:0034765 regulation of ion transmembrane transport 1.004089e-3
GO:0006733 oxidoreduction coenzyme metabolic process 1.005174e-3
GO:0045085 negative regulation of interleukin-2 biosynthetic process 1.012485e-3
GO:0060675 ureteric bud morphogenesis 1.030436e-3
GO:0009746 response to hexose stimulus 1.055060e-3
GO:0021537 telencephalon development 1.059102e-3
GO:2000142 regulation of transcription initiation, DNA-dependent 1.062773e-3
GO:0032781 positive regulation of ATPase activity 1.065299e-3
GO:0055014 atrial cardiac muscle cell development 1.068156e-3
GO:0072305 negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis 1.070783e-3
GO:2000594 positive regulation of metanephric DCT cell differentiation 1.070783e-3
GO:0039003 pronephric field specification 1.070783e-3
GO:0072593 reactive oxygen species metabolic process 1.073740e-3
GO:2000112 regulation of cellular macromolecule biosynthetic process 1.088292e-3
GO:0060419 heart growth 1.111997e-3
GO:0046651 lymphocyte proliferation 1.125809e-3
GO:0008284 positive regulation of cell proliferation 1.139287e-3
GO:0045542 positive regulation of cholesterol biosynthetic process 1.148724e-3
GO:0032715 negative regulation of interleukin-6 production 1.149331e-3
GO:0051929 positive regulation of calcium ion transport via voltage-gated calcium channel activity 1.153032e-3
GO:0015671 oxygen transport 1.161385e-3
GO:0090184 positive regulation of kidney development 1.175442e-3
GO:0001922 B-1 B cell homeostasis 1.176535e-3
GO:0031645 negative regulation of neurological system process 1.198889e-3
GO:0090292 nuclear matrix anchoring at nuclear membrane 1.202515e-3
GO:0006994 positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway 1.202515e-3
GO:0032957 inositol trisphosphate metabolic process 1.212738e-3
GO:0006811 ion transport 1.219965e-3
GO:0003015 heart process 1.223625e-3
GO:2000612 regulation of thyroid-stimulating hormone secretion 1.238178e-3
GO:0032802 low-density lipoprotein particle receptor catabolic process 1.238187e-3
GO:0055065 metal ion homeostasis 1.275925e-3
GO:0019748 secondary metabolic process 1.295783e-3
GO:0071400 cellular response to oleic acid 1.302314e-3
GO:0006941 striated muscle contraction 1.302663e-3
GO:0001656 metanephros development 1.337577e-3
GO:0072134 nephrogenic mesenchyme morphogenesis 1.343964e-3
GO:2000108 positive regulation of leukocyte apoptosis 1.355342e-3
GO:0008360 regulation of cell shape 1.355862e-3
GO:0051970 negative regulation of transmission of nerve impulse 1.358485e-3
GO:0006739 NADP metabolic process 1.361406e-3
GO:0060048 cardiac muscle contraction 1.362411e-3
GO:0001569 patterning of blood vessels 1.377277e-3
GO:0006548 histidine catabolic process 1.381434e-3
GO:0006621 protein retention in ER lumen 1.382152e-3
GO:0035725 sodium ion transmembrane transport 1.405385e-3
GO:0042135 neurotransmitter catabolic process 1.414119e-3
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1.420673e-3
GO:0048468 cell development 1.435597e-3
GO:2000696 regulation of epithelial cell differentiation involved in kidney development 1.439025e-3
GO:0022610 biological adhesion 1.452656e-3
GO:0072003 kidney rudiment formation 1.454255e-3
GO:0045602 negative regulation of endothelial cell differentiation 1.454255e-3
GO:0046700 heterocycle catabolic process 1.460594e-3
GO:0042424 catecholamine catabolic process 1.470695e-3
GO:0009074 aromatic amino acid family catabolic process 1.562563e-3
GO:0010288 response to lead ion 1.564537e-3
GO:0044281 small molecule metabolic process 1.565683e-3
GO:0007155 cell adhesion 1.593178e-3
GO:0045766 positive regulation of angiogenesis 1.637191e-3
GO:0035246 peptidyl-arginine N-methylation 1.637192e-3
GO:0032870 cellular response to hormone stimulus 1.648363e-3
GO:0009653 anatomical structure morphogenesis 1.650053e-3
GO:0046578 regulation of Ras protein signal transduction 1.656607e-3
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 1.666878e-3
GO:0000027 ribosomal large subunit assembly 1.666878e-3
GO:0071364 cellular response to epidermal growth factor stimulus 1.705311e-3
GO:0010959 regulation of metal ion transport 1.707615e-3
GO:0061138 morphogenesis of a branching epithelium 1.733791e-3
GO:0001822 kidney development 1.749023e-3
GO:0006766 vitamin metabolic process 1.786489e-3
GO:0030277 maintenance of gastrointestinal epithelium 1.824308e-3
GO:0070661 leukocyte proliferation 1.845926e-3
GO:0034754 cellular hormone metabolic process 1.861034e-3
GO:0042904 9-cis-retinoic acid biosynthetic process 1.870445e-3
GO:0001916 positive regulation of T cell mediated cytotoxicity 1.874028e-3
GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway 1.889799e-3
GO:0045787 positive regulation of cell cycle 1.900750e-3
GO:0007042 lysosomal lumen acidification 1.926401e-3
GO:0050805 negative regulation of synaptic transmission 1.929578e-3
GO:0071495 cellular response to endogenous stimulus 1.936255e-3
GO:0006603 phosphocreatine metabolic process 1.940698e-3
GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus 1.940698e-3
GO:0045046 protein import into peroxisome membrane 1.953859e-3
GO:0032854 positive regulation of Rap GTPase activity 1.966328e-3
GO:0006875 cellular metal ion homeostasis 1.966343e-3
GO:0060993 kidney morphogenesis 1.967581e-3
GO:0060055 angiogenesis involved in wound healing 1.970117e-3
GO:0032892 positive regulation of organic acid transport 1.970117e-3
GO:0018195 peptidyl-arginine modification 1.970117e-3
GO:0048569 post-embryonic organ development 1.994193e-3
GO:0000045 autophagic vacuole assembly 2.007431e-3
GO:0032943 mononuclear cell proliferation 2.024157e-3
GO:0014037 Schwann cell differentiation 2.051863e-3
GO:0051928 positive regulation of calcium ion transport 2.063984e-3
GO:0048821 erythrocyte development 2.076573e-3
GO:0007588 excretion 2.120965e-3
GO:0048522 positive regulation of cellular process 2.152341e-3
GO:0070830 tight junction assembly 2.156810e-3
GO:0072507 divalent inorganic cation homeostasis 2.198141e-3
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 2.250848e-3
GO:0034633 retinol transport 2.257378e-3
GO:0002551 mast cell chemotaxis 2.257378e-3
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 2.258326e-3
GO:0018216 peptidyl-arginine methylation 2.266514e-3
GO:0045947 negative regulation of translational initiation 2.274542e-3
GO:0006807 nitrogen compound metabolic process 2.282357e-3
GO:0032733 positive regulation of interleukin-10 production 2.304041e-3
GO:0035556 intracellular signal transduction 2.313620e-3
GO:0009889 regulation of biosynthetic process 2.313845e-3
GO:0032703 negative regulation of interleukin-2 production 2.326065e-3
GO:0006547 histidine metabolic process 2.328308e-3
GO:0002483 antigen processing and presentation of endogenous peptide antigen 2.328308e-3
GO:0051270 regulation of cellular component movement 2.328581e-3
GO:0070207 protein homotrimerization 2.334683e-3
GO:0002862 negative regulation of inflammatory response to antigenic stimulus 2.334688e-3
GO:0009651 response to salt stress 2.341225e-3
GO:0008633 activation of pro-apoptotic gene products 2.343360e-3
GO:2000347 positive regulation of hepatocyte proliferation 2.355339e-3
GO:0043401 steroid hormone mediated signaling pathway 2.363232e-3
GO:0071383 cellular response to steroid hormone stimulus 2.370857e-3
GO:0031326 regulation of cellular biosynthetic process 2.483472e-3
GO:0014888 striated muscle adaptation 2.489702e-3
GO:0048593 camera-type eye morphogenesis 2.523412e-3