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Novel motif:161

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name:motif161_CGGCTTGATT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 6.224177e-10
GO:0090086 negative regulation of protein deubiquitination 4.404815e-9
GO:0009084 glutamine family amino acid biosynthetic process 7.799066e-9
GO:0010983 positive regulation of high-density lipoprotein particle clearance 1.107606e-8
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 1.107606e-8
GO:0090085 regulation of protein deubiquitination 1.609274e-8
GO:0030433 ER-associated protein catabolic process 2.082875e-8
GO:0051382 kinetochore assembly 2.711195e-8
GO:0051383 kinetochore organization 5.515273e-8
GO:0031116 positive regulation of microtubule polymerization 6.313938e-8
GO:0021570 rhombomere 4 development 7.108751e-8
GO:0010561 negative regulation of glycoprotein biosynthetic process 1.211038e-7
GO:0014908 myotube differentiation involved in skeletal muscle regeneration 1.387916e-7
GO:0021569 rhombomere 3 development 1.460671e-7
GO:0043316 cytotoxic T cell degranulation 1.467622e-7
GO:0010986 positive regulation of lipoprotein particle clearance 1.467622e-7
GO:0034976 response to endoplasmic reticulum stress 2.212298e-7
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 2.385666e-7
GO:0021599 abducens nerve formation 2.385666e-7
GO:0007634 optokinetic behavior 2.385666e-7
GO:0002115 store-operated calcium entry 4.488657e-7
GO:0051915 induction of synaptic plasticity by chemical substance 6.678267e-7
GO:0050668 positive regulation of homocysteine metabolic process 6.684106e-7
GO:0045963 negative regulation of dopamine metabolic process 6.684106e-7
GO:0061384 heart trabecular morphogenesis 6.820397e-7
GO:0034699 response to luteinizing hormone stimulus 1.048196e-6
GO:0050652 dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 1.048196e-6
GO:0070389 chaperone cofactor-dependent protein refolding 1.130212e-6
GO:0006986 response to unfolded protein 1.387555e-6
GO:0021612 facial nerve structural organization 1.431352e-6
GO:0031112 positive regulation of microtubule polymerization or depolymerization 1.601103e-6
GO:0042026 protein refolding 1.656093e-6
GO:0022600 digestive system process 1.786411e-6
GO:0034637 cellular carbohydrate biosynthetic process 1.795289e-6
GO:0034508 centromere complex assembly 2.068668e-6
GO:0010459 negative regulation of heart rate 2.239845e-6
GO:0050666 regulation of homocysteine metabolic process 2.334316e-6
GO:0030101 natural killer cell activation 2.406885e-6
GO:0002285 lymphocyte activation involved in immune response 3.171872e-6
GO:0070885 negative regulation of calcineurin-NFAT signaling pathway 3.427226e-6
GO:0043320 natural killer cell degranulation 4.162023e-6
GO:0001578 microtubule bundle formation 5.237774e-6
GO:0021602 cranial nerve morphogenesis 6.017855e-6
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 6.179545e-6
GO:0060347 heart trabecula formation 6.349992e-6
GO:0090183 regulation of kidney development 6.677529e-6
GO:0051967 negative regulation of synaptic transmission, glutamatergic 7.309200e-6
GO:0048676 axon extension involved in development 7.351774e-6
GO:0090281 negative regulation of calcium ion import 7.564613e-6
GO:0071584 negative regulation of zinc ion import 7.564613e-6
GO:0007586 digestion 8.041201e-6
GO:0042267 natural killer cell mediated cytotoxicity 9.319660e-6
GO:0010734 negative regulation of protein glutathionylation 9.761260e-6
GO:0002689 negative regulation of leukocyte chemotaxis 9.844655e-6
GO:0051310 metaphase plate congression 1.083290e-5
GO:0033240 positive regulation of cellular amine metabolic process 1.097966e-5
GO:0032203 telomere formation via telomerase 1.103480e-5
GO:0048532 anatomical structure arrangement 1.223457e-5
GO:0032230 positive regulation of synaptic transmission, GABAergic 1.426828e-5
GO:0060876 semicircular canal formation 1.500801e-5
GO:0034766 negative regulation of ion transmembrane transport 1.697557e-5
GO:0035966 response to topologically incorrect protein 1.891767e-5
GO:0006797 polyphosphate metabolic process 1.915958e-5
GO:0021546 rhombomere development 1.991344e-5
GO:0048639 positive regulation of developmental growth 2.037916e-5
GO:0010982 regulation of high-density lipoprotein particle clearance 2.075835e-5
GO:0007518 myoblast cell fate determination 2.466523e-5
GO:0032237 activation of store-operated calcium channel activity 2.512381e-5
GO:0045116 protein neddylation 2.549812e-5
GO:0042984 regulation of amyloid precursor protein biosynthetic process 2.827345e-5
GO:0031113 regulation of microtubule polymerization 2.986889e-5
GO:0021610 facial nerve morphogenesis 2.992379e-5
GO:0021603 cranial nerve formation 3.046078e-5
GO:0061162 establishment of monopolar cell polarity 3.181376e-5
GO:0045927 positive regulation of growth 3.183199e-5
GO:0060676 ureteric bud formation 3.242733e-5
GO:0060300 regulation of cytokine activity 3.642847e-5
GO:0048793 pronephros development 3.921833e-5
GO:0042797 tRNA transcription from RNA polymerase III promoter 4.085535e-5
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 4.085535e-5
GO:0071585 detoxification of cadmium ion 4.568540e-5
GO:0021561 facial nerve development 4.924189e-5
GO:0051654 establishment of mitochondrion localization 5.321877e-5
GO:0000236 mitotic prometaphase 5.322265e-5
GO:0030509 BMP signaling pathway 5.429249e-5
GO:0006537 glutamate biosynthetic process 5.695615e-5
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 6.327810e-5
GO:0002312 B cell activation involved in immune response 7.258731e-5
GO:0006421 asparaginyl-tRNA aminoacylation 7.775831e-5
GO:0090084 negative regulation of inclusion body assembly 7.809780e-5
GO:0048144 fibroblast proliferation 8.504764e-5
GO:0072205 metanephric collecting duct development 8.905504e-5
GO:0001909 leukocyte mediated cytotoxicity 9.033504e-5
GO:0033120 positive regulation of RNA splicing 9.114967e-5
GO:0030968 endoplasmic reticulum unfolded protein response 9.642439e-5
GO:0060409 positive regulation of acetylcholine metabolic process 1.023565e-4
GO:0009304 tRNA transcription 1.054696e-4
GO:0002316 follicular B cell differentiation 1.054696e-4
GO:0021604 cranial nerve structural organization 1.103780e-4
GO:0006542 glutamine biosynthetic process 1.162105e-4
GO:2000353 positive regulation of endothelial cell apoptosis 1.187115e-4
GO:0016051 carbohydrate biosynthetic process 1.190829e-4
GO:0009236 cobalamin biosynthetic process 1.222616e-4
GO:0045822 negative regulation of heart contraction 1.279977e-4
GO:0051973 positive regulation of telomerase activity 1.312573e-4
GO:0047497 mitochondrion transport along microtubule 1.349536e-4
GO:0006268 DNA unwinding involved in replication 1.404500e-4
GO:0021754 facial nucleus development 1.453214e-4
GO:0060301 positive regulation of cytokine activity 1.546427e-4
GO:0046184 aldehyde biosynthetic process 1.546427e-4
GO:0006538 glutamate catabolic process 1.664979e-4
GO:0006457 protein folding 1.883894e-4
GO:0001832 blastocyst growth 1.927128e-4
GO:0033692 cellular polysaccharide biosynthetic process 1.954768e-4
GO:0072215 regulation of metanephros development 1.998595e-4
GO:0072060 outer medullary collecting duct development 2.000195e-4
GO:0072061 inner medullary collecting duct development 2.000195e-4
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 2.000195e-4
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 2.000195e-4
GO:0072110 glomerular mesangial cell proliferation 2.048531e-4
GO:0002456 T cell mediated immunity 2.207453e-4
GO:0048754 branching morphogenesis of a tube 2.248334e-4
GO:0002366 leukocyte activation involved in immune response 2.312848e-4
GO:0060318 definitive erythrocyte differentiation 2.328483e-4
GO:0043501 skeletal muscle adaptation 2.404243e-4
GO:0034088 maintenance of mitotic sister chromatid cohesion 2.501701e-4
GO:0009620 response to fungus 2.593368e-4
GO:0048638 regulation of developmental growth 2.595853e-4
GO:0090083 regulation of inclusion body assembly 2.653262e-4
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 2.697708e-4
GO:0035115 embryonic forelimb morphogenesis 2.716181e-4
GO:0046007 negative regulation of activated T cell proliferation 2.757253e-4
GO:0032202 telomere assembly 2.855563e-4
GO:0032660 regulation of interleukin-17 production 3.221671e-4
GO:0045907 positive regulation of vasoconstriction 3.407746e-4
GO:0072126 positive regulation of glomerular mesangial cell proliferation 3.552534e-4
GO:0046541 saliva secretion 3.552534e-4
GO:0071506 cellular response to mycophenolic acid 3.552534e-4
GO:0051156 glucose 6-phosphate metabolic process 3.654638e-4
GO:0007522 visceral muscle development 3.701400e-4
GO:0070925 organelle assembly 3.834859e-4
GO:0035136 forelimb morphogenesis 3.869393e-4
GO:0030308 negative regulation of cell growth 3.888864e-4
GO:0045764 positive regulation of cellular amino acid metabolic process 3.940656e-4
GO:0035117 embryonic arm morphogenesis 3.940656e-4
GO:0014888 striated muscle adaptation 3.948389e-4
GO:0000733 DNA strand renaturation 4.086744e-4
GO:0061387 regulation of extent of cell growth 4.288638e-4
GO:0032958 inositol phosphate biosynthetic process 4.319817e-4
GO:0043266 regulation of potassium ion transport 4.321934e-4
GO:0050849 negative regulation of calcium-mediated signaling 4.359062e-4
GO:0060074 synapse maturation 4.402461e-4
GO:0045773 positive regulation of axon extension 4.521407e-4
GO:0033239 negative regulation of cellular amine metabolic process 4.656207e-4
GO:0032224 positive regulation of synaptic transmission, cholinergic 4.656207e-4
GO:0061084 negative regulation of protein refolding 4.776372e-4
GO:0072109 glomerular mesangium development 4.776372e-4
GO:0060444 branching involved in mammary gland duct morphogenesis 4.989441e-4
GO:0030516 regulation of axon extension 5.090989e-4
GO:0060356 leucine import 5.115825e-4
GO:0007059 chromosome segregation 5.145444e-4
GO:0031110 regulation of microtubule polymerization or depolymerization 5.211846e-4
GO:0072044 collecting duct development 5.212449e-4
GO:0000085 G2 phase of mitotic cell cycle 5.270117e-4
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 5.557213e-4
GO:0034441 plasma lipoprotein particle oxidation 6.021531e-4
GO:0032236 positive regulation of calcium ion transport via store-operated calcium channel activity 6.048628e-4
GO:0043484 regulation of RNA splicing 6.049534e-4
GO:0007064 mitotic sister chromatid cohesion 6.067609e-4
GO:0010984 regulation of lipoprotein particle clearance 6.143754e-4
GO:0060629 regulation of homologous chromosome segregation 6.495199e-4
GO:0051598 meiotic recombination checkpoint 6.495199e-4
GO:0050703 interleukin-1 alpha secretion 6.948275e-4
GO:0002729 positive regulation of natural killer cell cytokine production 6.948275e-4
GO:0061099 negative regulation of protein tyrosine kinase activity 6.985497e-4
GO:0002313 mature B cell differentiation involved in immune response 7.075056e-4
GO:0009205 purine ribonucleoside triphosphate metabolic process 7.152771e-4
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 7.396185e-4
GO:0035967 cellular response to topologically incorrect protein 7.403598e-4
GO:0002026 regulation of the force of heart contraction 7.403598e-4
GO:0045348 positive regulation of MHC class II biosynthetic process 7.545146e-4
GO:0009199 ribonucleoside triphosphate metabolic process 7.629213e-4
GO:0021545 cranial nerve development 7.700435e-4
GO:0046364 monosaccharide biosynthetic process 7.834690e-4
GO:0030307 positive regulation of cell growth 7.918224e-4
GO:0043415 positive regulation of skeletal muscle tissue regeneration 8.186859e-4
GO:0070884 regulation of calcineurin-NFAT signaling pathway 8.495929e-4
GO:0043268 positive regulation of potassium ion transport 9.177952e-4
GO:0030277 maintenance of gastrointestinal epithelium 9.214181e-4
GO:0046929 negative regulation of neurotransmitter secretion 9.464532e-4
GO:0019319 hexose biosynthetic process 9.564517e-4
GO:0002769 natural killer cell inhibitory signaling pathway 9.573565e-4
GO:0051775 response to redox state 9.903122e-4
GO:0021783 preganglionic parasympathetic nervous system development 1.000752e-3
GO:0014012 peripheral nervous system axon regeneration 1.000752e-3
GO:0061138 morphogenesis of a branching epithelium 1.003053e-3
GO:0048675 axon extension 1.015292e-3
GO:0060482 lobar bronchus development 1.043467e-3
GO:0060600 dichotomous subdivision of an epithelial terminal unit 1.048374e-3
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 1.056658e-3
GO:0071398 cellular response to fatty acid 1.061366e-3
GO:0046884 follicle-stimulating hormone secretion 1.088457e-3
GO:0032275 luteinizing hormone secretion 1.088457e-3
GO:0072668 tubulin complex biogenesis 1.102218e-3
GO:0002027 regulation of heart rate 1.102231e-3
GO:0072283 metanephric renal vesicle morphogenesis 1.190069e-3
GO:0045660 positive regulation of neutrophil differentiation 1.245647e-3
GO:0009144 purine nucleoside triphosphate metabolic process 1.260671e-3
GO:0006084 acetyl-CoA metabolic process 1.264729e-3
GO:0033119 negative regulation of RNA splicing 1.287045e-3
GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 1.301329e-3
GO:0060628 regulation of ER to Golgi vesicle-mediated transport 1.343925e-3
GO:0070574 cadmium ion transmembrane transport 1.347635e-3
GO:0072087 renal vesicle development 1.362768e-3
GO:0060992 response to fungicide 1.371104e-3
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1.391667e-3
GO:0043950 positive regulation of cAMP-mediated signaling 1.418985e-3
GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development 1.418985e-3
GO:0001833 inner cell mass cell proliferation 1.423844e-3
GO:0002238 response to molecule of fungal origin 1.424584e-3
GO:0051646 mitochondrion localization 1.431340e-3
GO:0001696 gastric acid secretion 1.463071e-3
GO:0007026 negative regulation of microtubule depolymerization 1.514371e-3
GO:0060560 developmental growth involved in morphogenesis 1.540772e-3
GO:0035409 histone H3-Y41 phosphorylation 1.542080e-3
GO:0008636 activation of caspase activity by protein phosphorylation 1.542080e-3
GO:0014732 skeletal muscle atrophy 1.586069e-3
GO:0001824 blastocyst development 1.649469e-3
GO:0050922 negative regulation of chemotaxis 1.657656e-3
GO:0021636 trigeminal nerve morphogenesis 1.716961e-3
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 1.750066e-3
GO:0010959 regulation of metal ion transport 1.925513e-3
GO:0072077 renal vesicle morphogenesis 1.931496e-3
GO:0031114 regulation of microtubule depolymerization 1.985736e-3
GO:0003338 metanephros morphogenesis 2.001722e-3
GO:0048554 positive regulation of metalloenzyme activity 2.003787e-3
GO:0018027 peptidyl-lysine dimethylation 2.003787e-3
GO:0032024 positive regulation of insulin secretion 2.009838e-3
GO:0061077 chaperone-mediated protein folding 2.034370e-3
GO:0090277 positive regulation of peptide hormone secretion 2.078688e-3
GO:0048739 cardiac muscle fiber development 2.079263e-3
GO:0019408 dolichol biosynthetic process 2.158600e-3
GO:0071481 cellular response to X-ray 2.160414e-3
GO:0048305 immunoglobulin secretion 2.160414e-3
GO:0010388 cullin deneddylation 2.298181e-3
GO:0007023 post-chaperonin tubulin folding pathway 2.298719e-3
GO:0007050 cell cycle arrest 2.324931e-3
GO:0071526 semaphorin-plexin signaling pathway 2.348011e-3
GO:0045084 positive regulation of interleukin-12 biosynthetic process 2.360413e-3
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation 2.364663e-3
GO:0050746 regulation of lipoprotein metabolic process 2.364663e-3
GO:0010477 response to sulfur dioxide 2.379266e-3
GO:0002457 T cell antigen processing and presentation 2.379266e-3
GO:0002793 positive regulation of peptide secretion 2.394095e-3
GO:0009150 purine ribonucleotide metabolic process 2.402939e-3
GO:0061383 trabecula morphogenesis 2.440934e-3
GO:0009404 toxin metabolic process 2.459984e-3
GO:0009154 purine ribonucleotide catabolic process 2.493923e-3
GO:0006264 mitochondrial DNA replication 2.509112e-3
GO:0045786 negative regulation of cell cycle 2.590712e-3
GO:0051303 establishment of chromosome localization 2.641274e-3
GO:0055009 atrial cardiac muscle tissue morphogenesis 2.644815e-3
GO:0007214 gamma-aminobutyric acid signaling pathway 2.644815e-3
GO:0009141 nucleoside triphosphate metabolic process 2.665136e-3
GO:0061010 gall bladder development 2.733633e-3
GO:0035261 external genitalia morphogenesis 2.733633e-3
GO:0007181 transforming growth factor beta receptor complex assembly 2.733633e-3
GO:0030259 lipid glycosylation 2.743285e-3
GO:0055091 phospholipid homeostasis 2.751506e-3
GO:0009261 ribonucleotide catabolic process 2.818746e-3
GO:0002121 inter-male aggressive behavior 2.853466e-3
GO:0017085 response to insecticide 2.868940e-3
GO:0046887 positive regulation of hormone secretion 2.888005e-3
GO:0001834 trophectodermal cell proliferation 2.926723e-3
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 2.926723e-3
GO:0007402 ganglion mother cell fate determination 2.926723e-3
GO:0048486 parasympathetic nervous system development 2.941705e-3
GO:0048012 hepatocyte growth factor receptor signaling pathway 3.019161e-3
GO:0002335 mature B cell differentiation 3.046531e-3
GO:0043615 astrocyte cell migration 3.090021e-3
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.090021e-3
GO:2000602 regulation of interphase of mitotic cell cycle 3.160842e-3
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 3.206878e-3
GO:0010159 specification of organ position 3.227377e-3
GO:0090279 regulation of calcium ion import 3.276346e-3
GO:0009207 purine ribonucleoside triphosphate catabolic process 3.293509e-3
GO:0043508 negative regulation of JUN kinase activity 3.303577e-3
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 3.307817e-3
GO:2000045 regulation of G1/S transition of mitotic cell cycle 3.335732e-3
GO:0007217 tachykinin receptor signaling pathway 3.386953e-3
GO:0009636 response to toxin 3.423020e-3
GO:0009313 oligosaccharide catabolic process 3.472680e-3
GO:0048588 developmental cell growth 3.636248e-3
GO:0042632 cholesterol homeostasis 3.643807e-3
GO:0009146 purine nucleoside triphosphate catabolic process 3.669287e-3
GO:0061038 uterus morphogenesis 3.678001e-3
GO:0070509 calcium ion import 3.778306e-3
GO:0050804 regulation of synaptic transmission 3.783891e-3
GO:0060904 regulation of protein folding in endoplasmic reticulum 3.801771e-3
GO:0070060 'de novo' actin filament nucleation 3.801771e-3
GO:0039020 pronephric nephron tubule development 3.801771e-3
GO:0035565 regulation of pronephros size 3.801771e-3
GO:0021589 cerebellum structural organization 3.801771e-3
GO:0045591 positive regulation of regulatory T cell differentiation 3.863052e-3
GO:0070914 UV-damage excision repair 3.863052e-3
GO:0051177 meiotic sister chromatid cohesion 3.863052e-3
GO:0043060 meiotic metaphase I plate congression 3.863052e-3
GO:0019242 methylglyoxal biosynthetic process 3.863052e-3
GO:0032228 regulation of synaptic transmission, GABAergic 3.973909e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 4.088567e-3
GO:0048702 embryonic neurocranium morphogenesis 4.088567e-3
GO:0045019 negative regulation of nitric oxide biosynthetic process 4.143661e-3
GO:0031915 positive regulation of synaptic plasticity 4.272850e-3
GO:0071985 multivesicular body sorting pathway 4.351991e-3
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development 4.351991e-3
GO:0018022 peptidyl-lysine methylation 4.351991e-3
GO:0060399 positive regulation of growth hormone receptor signaling pathway 4.399288e-3
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 4.399288e-3
GO:0030510 regulation of BMP signaling pathway 4.454807e-3
GO:0009143 nucleoside triphosphate catabolic process 4.669113e-3
GO:0051036 regulation of endosome size 4.676049e-3
GO:0046426 negative regulation of JAK-STAT cascade 4.959565e-3
GO:0071459 protein localization to chromosome, centromeric region 4.983462e-3
GO:0033590 response to cobalamin 4.983462e-3
GO:0006117 acetaldehyde metabolic process 4.983462e-3
GO:0030187 melatonin biosynthetic process 4.983462e-3
GO:0009438 methylglyoxal metabolic process 4.983462e-3
GO:0032042 mitochondrial DNA metabolic process 5.108695e-3
GO:0007130 synaptonemal complex assembly 5.113925e-3
GO:0033031 positive regulation of neutrophil apoptosis 5.185617e-3
GO:0070165 positive regulation of adiponectin secretion 5.185617e-3
GO:0035767 endothelial cell chemotaxis 5.388032e-3
GO:0006094 gluconeogenesis 5.489701e-3
GO:0007210 serotonin receptor signaling pathway 5.543773e-3
GO:0030540 female genitalia development 5.543773e-3
GO:0050832 defense response to fungus 5.549506e-3
GO:0042351 'de novo' GDP-L-fucose biosynthetic process 5.595230e-3
GO:0009051 pentose-phosphate shunt, oxidative branch 5.617423e-3
GO:0032513 negative regulation of protein phosphatase type 2B activity 5.649043e-3
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 5.723729e-3
GO:0051260 protein homooligomerization 5.764666e-3
GO:0032402 melanosome transport 5.868732e-3
GO:0072054 renal outer medulla development 5.885036e-3
GO:0072053 renal inner medulla development 5.885036e-3
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 5.885036e-3
GO:0021571 rhombomere 5 development 5.885036e-3
GO:0009259 ribonucleotide metabolic process 5.903075e-3
GO:0006184 GTP catabolic process 5.970541e-3
GO:0006984 ER-nucleus signaling pathway 5.988837e-3
GO:0032959 inositol trisphosphate biosynthetic process 6.047924e-3
GO:0071479 cellular response to ionizing radiation 6.100647e-3
GO:0002686 negative regulation of leukocyte migration 6.139302e-3
GO:0019062 virion attachment to host cell surface receptor 6.182703e-3
GO:0001906 cell killing 6.207060e-3
GO:0051972 regulation of telomerase activity 6.211474e-3
GO:0043242 negative regulation of protein complex disassembly 6.260064e-3
GO:0001558 regulation of cell growth 6.307360e-3
GO:0072012 glomerulus vasculature development 6.447525e-3
GO:0033002 muscle cell proliferation 6.578372e-3
GO:0032689 negative regulation of interferon-gamma production 6.632181e-3
GO:0045658 regulation of neutrophil differentiation 6.634885e-3
GO:0001732 formation of translation initiation complex 6.634885e-3
GO:0043299 leukocyte degranulation 6.673615e-3
GO:0030149 sphingolipid catabolic process 6.673615e-3
GO:0006383 transcription from RNA polymerase III promoter 6.730374e-3
GO:0015805 S-adenosylmethionine transport 6.741572e-3
GO:0002765 immune response-inhibiting signal transduction 6.741572e-3
GO:0031103 axon regeneration 6.780643e-3
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 6.913707e-3
GO:0006195 purine nucleotide catabolic process 6.957829e-3
GO:0050860 negative regulation of T cell receptor signaling pathway 7.018537e-3
GO:0007028 cytoplasm organization 7.041834e-3
GO:0055017 cardiac muscle tissue growth 7.198026e-3
GO:0060535 trachea cartilage morphogenesis 7.205846e-3
GO:0072089 stem cell proliferation 7.205846e-3
GO:0033687 osteoblast proliferation 7.205846e-3
GO:0006561 proline biosynthetic process 7.205846e-3
GO:0031111 negative regulation of microtubule polymerization or depolymerization 7.313963e-3
GO:0090192 regulation of glomerulus development 7.530590e-3
GO:0032273 positive regulation of protein polymerization 7.550480e-3
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 7.650990e-3
GO:0051102 DNA ligation involved in DNA recombination 7.658296e-3
GO:0006425 glutaminyl-tRNA aminoacylation 7.658296e-3
GO:0071243 cellular response to arsenic-containing substance 7.690159e-3
GO:0009395 phospholipid catabolic process 7.762367e-3
GO:0000080 G1 phase of mitotic cell cycle 7.765959e-3
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 7.935321e-3
GO:0070358 actin polymerization-dependent cell motility 7.950921e-3
GO:0060343 trabecula formation 7.995030e-3
GO:0003229 ventricular cardiac muscle tissue development 8.015681e-3
GO:0032792 negative regulation of CREB transcription factor activity 8.024581e-3
GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 8.388084e-3
GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway 8.436896e-3
GO:0003416 endochondral bone growth 8.563612e-3
GO:0060419 heart growth 8.598315e-3
GO:0043933 macromolecular complex subunit organization 8.627311e-3
GO:0043623 cellular protein complex assembly 8.688317e-3
GO:0043697 cell dedifferentiation 8.728357e-3
GO:2000773 negative regulation of cellular senescence 8.728357e-3
GO:0046039 GTP metabolic process 8.822507e-3
GO:0048483 autonomic nervous system development 8.849520e-3
GO:0006982 response to lipid hydroperoxide 9.090396e-3
GO:0061180 mammary gland epithelium development 9.185093e-3
GO:0055010 ventricular cardiac muscle tissue morphogenesis 9.195943e-3
GO:0046320 regulation of fatty acid oxidation 9.247121e-3
GO:0072181 mesonephric duct formation 9.279737e-3
GO:0042138 meiotic DNA double-strand break formation 9.279737e-3
GO:0034314 Arp2/3 complex-mediated actin nucleation 9.279737e-3
GO:0033313 meiotic cell cycle checkpoint 9.279737e-3
GO:0070271 protein complex biogenesis 9.353283e-3
GO:0046466 membrane lipid catabolic process 9.366574e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 9.575541e-3
GO:0032383 regulation of intracellular cholesterol transport 9.594235e-3
GO:0051904 pigment granule transport 9.743341e-3
GO:0045750 positive regulation of S phase of mitotic cell cycle 9.810622e-3
GO:0072384 organelle transport along microtubule 9.879506e-3
GO:0048535 lymph node development 9.931126e-3
GO:0033233 regulation of protein sumoylation 1.006772e-2
GO:0072111 cell proliferation involved in kidney development 1.020061e-2
GO:0045926 negative regulation of growth 1.033829e-2
GO:0009166 nucleotide catabolic process 1.036707e-2
GO:0050687 negative regulation of defense response to virus 1.046819e-2
GO:0032222 regulation of synaptic transmission, cholinergic 1.046819e-2
GO:0032793 positive regulation of CREB transcription factor activity 1.047409e-2
GO:0072355 histone H3-T3 phosphorylation 1.055636e-2
GO:0015706 nitrate transport 1.055636e-2
GO:0010571 positive regulation of DNA replication involved in S phase 1.055636e-2
GO:0035880 embryonic nail plate morphogenesis 1.056209e-2
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1.073028e-2
GO:0060688 regulation of morphogenesis of a branching structure 1.081400e-2
GO:0010669 epithelial structure maintenance 1.088477e-2
GO:0042594 response to starvation 1.089642e-2
GO:0001763 morphogenesis of a branching structure 1.091422e-2
GO:0046165 alcohol biosynthetic process 1.098156e-2
GO:0006878 cellular copper ion homeostasis 1.104606e-2
GO:0043270 positive regulation of ion transport 1.112395e-2
GO:0030490 maturation of SSU-rRNA 1.114431e-2
GO:0018026 peptidyl-lysine monomethylation 1.114431e-2
GO:0072523 purine-containing compound catabolic process 1.133628e-2
GO:0008333 endosome to lysosome transport 1.140192e-2
GO:0001714 endodermal cell fate specification 1.152405e-2
GO:0016049 cell growth 1.162330e-2
GO:0032740 positive regulation of interleukin-17 production 1.166479e-2
GO:0060675 ureteric bud morphogenesis 1.168446e-2
GO:0001657 ureteric bud development 1.194902e-2
GO:0048521 negative regulation of behavior 1.201390e-2
GO:2000543 positive regulation of gastrulation 1.202965e-2
GO:0001656 metanephros development 1.208844e-2
GO:0015827 tryptophan transport 1.214723e-2
GO:0032700 negative regulation of interleukin-17 production 1.226401e-2
GO:0022617 extracellular matrix disassembly 1.228848e-2
GO:0051257 spindle midzone assembly involved in meiosis 1.230444e-2
GO:0009235 cobalamin metabolic process 1.230444e-2
GO:0007060 male meiosis chromosome segregation 1.230444e-2
GO:0055008 cardiac muscle tissue morphogenesis 1.234726e-2
GO:0021559 trigeminal nerve development 1.250862e-2
GO:0050686 negative regulation of mRNA processing 1.255136e-2
GO:0032543 mitochondrial translation 1.255136e-2
GO:0019348 dolichol metabolic process 1.268167e-2
GO:0034698 response to gonadotropin stimulus 1.298387e-2
GO:0048672 positive regulation of collateral sprouting 1.300302e-2
GO:0006000 fructose metabolic process 1.300822e-2
GO:0034622 cellular macromolecular complex assembly 1.310776e-2
GO:0060534 trachea cartilage development 1.315214e-2
GO:0050651 dermatan sulfate proteoglycan biosynthetic process 1.315214e-2
GO:0048265 response to pain 1.316381e-2
GO:0065003 macromolecular complex assembly 1.324759e-2
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 1.337869e-2
GO:0050806 positive regulation of synaptic transmission 1.346599e-2
GO:0048008 platelet-derived growth factor receptor signaling pathway 1.358243e-2
GO:0072009 nephron epithelium development 1.370162e-2
GO:0051081 nuclear envelope disassembly 1.383591e-2
GO:0035694 mitochondrial protein catabolic process 1.383591e-2
GO:0061015 snRNA import into nucleus 1.385864e-2
GO:0001880 Mullerian duct regression 1.389857e-2
GO:0046293 formaldehyde biosynthetic process 1.400376e-2
GO:0060133 somatotropin secreting cell development 1.400376e-2
GO:0043152 induction of bacterial agglutination 1.400376e-2
GO:0051966 regulation of synaptic transmission, glutamatergic 1.401923e-2
GO:0002449 lymphocyte mediated immunity 1.416243e-2
GO:0000302 response to reactive oxygen species 1.420796e-2
GO:0072124 regulation of glomerular mesangial cell proliferation 1.421591e-2
GO:0072148 epithelial cell fate commitment 1.421591e-2
GO:0032414 positive regulation of ion transmembrane transporter activity 1.430595e-2
GO:0051209 release of sequestered calcium ion into cytosol 1.475413e-2
GO:0032401 establishment of melanosome localization 1.481858e-2
GO:0060596 mammary placode formation 1.482651e-2
GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein 1.483464e-2
GO:0060173 limb development 1.522296e-2
GO:0060433 bronchus development 1.541127e-2
GO:0072298 regulation of metanephric glomerulus development 1.541127e-2
GO:2000594 positive regulation of metanephric DCT cell differentiation 1.545697e-2
GO:0072305 negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis 1.545697e-2
GO:0050655 dermatan sulfate proteoglycan metabolic process 1.545697e-2
GO:0039003 pronephric field specification 1.545697e-2
GO:0048738 cardiac muscle tissue development 1.562223e-2
GO:0051318 G1 phase 1.578629e-2
GO:0000239 pachytene 1.581195e-2
GO:0003051 angiotensin-mediated drinking behavior 1.582946e-2
GO:0019047 provirus integration 1.587797e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0045780 positive regulation of bone resorption 1.420312e-11
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 1.746931e-10
GO:0034105 positive regulation of tissue remodeling 8.749481e-10
GO:0030502 negative regulation of bone mineralization 2.569866e-9
GO:0070168 negative regulation of biomineral tissue development 3.250123e-9
GO:0046627 negative regulation of insulin receptor signaling pathway 1.079422e-8
GO:0045124 regulation of bone resorption 1.932325e-8
GO:0006936 muscle contraction 2.381440e-8
GO:0048496 maintenance of organ identity 3.346899e-8
GO:0046850 regulation of bone remodeling 5.280895e-8
GO:0009236 cobalamin biosynthetic process 6.022777e-8
GO:0006953 acute-phase response 1.169967e-7
GO:0017196 N-terminal peptidyl-methionine acetylation 1.579771e-7
GO:0031100 organ regeneration 5.404450e-7
GO:0007059 chromosome segregation 5.930278e-7
GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 7.413020e-7
GO:0031987 locomotion involved in locomotory behavior 1.206404e-6
GO:0046626 regulation of insulin receptor signaling pathway 3.616568e-6
GO:0090231 regulation of spindle checkpoint 4.019155e-6
GO:0046341 CDP-diacylglycerol metabolic process 4.412856e-6
GO:0031161 phosphatidylinositol catabolic process 5.027169e-6
GO:0060986 endocrine hormone secretion 7.030690e-6
GO:0034337 RNA folding 7.110288e-6
GO:0034103 regulation of tissue remodeling 7.477467e-6
GO:0070166 enamel mineralization 7.484708e-6
GO:0061301 cerebellum vasculature morphogenesis 7.548455e-6
GO:0045210 FasL biosynthetic process 7.548455e-6
GO:0006348 chromatin silencing at telomere 7.650979e-6
GO:0044029 hypomethylation of CpG island 1.220624e-5
GO:0032846 positive regulation of homeostatic process 1.525064e-5
GO:0045948 positive regulation of translational initiation 1.578014e-5
GO:0050766 positive regulation of phagocytosis 1.838390e-5
GO:0018206 peptidyl-methionine modification 2.050036e-5
GO:0022613 ribonucleoprotein complex biogenesis 2.331510e-5
GO:0021987 cerebral cortex development 2.381616e-5
GO:0071843 cellular component biogenesis at cellular level 2.512803e-5
GO:2000279 negative regulation of DNA biosynthetic process 2.778756e-5
GO:0046960 sensitization 2.876436e-5
GO:0007076 mitotic chromosome condensation 3.010589e-5
GO:0002526 acute inflammatory response 3.234128e-5
GO:0030308 negative regulation of cell growth 3.289150e-5
GO:0050764 regulation of phagocytosis 4.069736e-5
GO:0030263 apoptotic chromosome condensation 4.634857e-5
GO:0030279 negative regulation of ossification 4.839492e-5
GO:0003012 muscle system process 4.936762e-5
GO:0000715 nucleotide-excision repair, DNA damage recognition 5.900484e-5
GO:0044030 regulation of DNA methylation 5.997888e-5
GO:0032402 melanosome transport 6.216704e-5
GO:0006941 striated muscle contraction 6.453133e-5
GO:0048633 positive regulation of skeletal muscle tissue growth 6.569273e-5
GO:0031099 regeneration 6.802116e-5
GO:0070986 left/right axis specification 7.416928e-5
GO:0048743 positive regulation of skeletal muscle fiber development 8.760720e-5
GO:0009235 cobalamin metabolic process 9.216508e-5
GO:0035106 operant conditioning 9.340357e-5
GO:0006370 mRNA capping 9.373235e-5
GO:0000028 ribosomal small subunit assembly 1.017542e-4
GO:0015992 proton transport 1.268675e-4
GO:0032800 receptor biosynthetic process 1.334633e-4
GO:0043049 otic placode formation 1.380418e-4
GO:0006818 hydrogen transport 1.443518e-4
GO:0021636 trigeminal nerve morphogenesis 1.451654e-4
GO:0045212 neurotransmitter receptor biosynthetic process 1.451654e-4
GO:0035572 N-terminal peptidyl-serine dimethylation 1.463473e-4
GO:0035573 N-terminal peptidyl-serine trimethylation 1.463473e-4
GO:0021528 commissural neuron differentiation in spinal cord 1.463473e-4
GO:0018012 N-terminal peptidyl-alanine trimethylation 1.463473e-4
GO:0018016 N-terminal peptidyl-proline dimethylation 1.463473e-4
GO:0022618 ribonucleoprotein complex assembly 1.721092e-4
GO:0042640 anagen 1.748721e-4
GO:0003148 outflow tract septum morphogenesis 1.749273e-4
GO:0060972 left/right pattern formation 2.671110e-4
GO:0051904 pigment granule transport 2.671110e-4
GO:0032911 negative regulation of transforming growth factor beta1 production 2.671110e-4
GO:0006888 ER to Golgi vesicle-mediated transport 2.827744e-4
GO:0060286 flagellar cell motility 2.919194e-4
GO:0006601 creatine biosynthetic process 2.919194e-4
GO:0071826 ribonucleoprotein complex subunit organization 3.077729e-4
GO:0042274 ribosomal small subunit biogenesis 3.454161e-4
GO:0009452 RNA capping 3.523389e-4
GO:0032401 establishment of melanosome localization 3.552895e-4
GO:0007080 mitotic metaphase plate congression 3.552895e-4
GO:0032274 gonadotropin secretion 3.640759e-4
GO:0035426 extracellular matrix-cell signaling 3.831357e-4
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 3.839003e-4
GO:0031365 N-terminal protein amino acid modification 3.871575e-4
GO:0021895 cerebral cortex neuron differentiation 4.145649e-4
GO:0000070 mitotic sister chromatid segregation 4.322167e-4
GO:0048631 regulation of skeletal muscle tissue growth 4.606942e-4
GO:0032400 melanosome localization 4.845019e-4
GO:0021543 pallium development 4.854135e-4
GO:2000171 negative regulation of dendrite development 5.124227e-4
GO:0048643 positive regulation of skeletal muscle tissue development 5.180843e-4
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 5.527212e-4
GO:0061304 retinal blood vessel morphogenesis 5.881663e-4
GO:0090288 negative regulation of cellular response to growth factor stimulus 6.370132e-4
GO:0040030 regulation of molecular function, epigenetic 6.720007e-4
GO:0048672 positive regulation of collateral sprouting 6.720007e-4
GO:0009957 epidermal cell fate specification 6.720007e-4
GO:0048820 hair follicle maturation 7.020572e-4
GO:0032908 regulation of transforming growth factor beta1 production 7.386167e-4
GO:2000278 regulation of DNA biosynthetic process 7.712180e-4
GO:0045746 negative regulation of Notch signaling pathway 7.712180e-4
GO:0000819 sister chromatid segregation 7.997461e-4
GO:0097152 mesenchymal cell apoptosis 8.275811e-4
GO:0046958 nonassociative learning 8.294566e-4
GO:0045930 negative regulation of mitotic cell cycle 8.402849e-4
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 8.660838e-4
GO:0021997 neural plate axis specification 9.884645e-4
GO:0051905 establishment of pigment granule localization 1.040475e-3
GO:0006054 N-acetylneuraminate metabolic process 1.040475e-3
GO:0048640 negative regulation of developmental growth 1.078404e-3
GO:0046605 regulation of centrosome cycle 1.090338e-3
GO:0035239 tube morphogenesis 1.106616e-3
GO:0042384 cilium assembly 1.114175e-3
GO:0042989 sequestering of actin monomers 1.119745e-3
GO:0060809 mesodermal to mesenchymal transition involved in gastrulation 1.121239e-3
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 1.121239e-3
GO:0006587 serotonin biosynthetic process from tryptophan 1.150037e-3
GO:0051875 pigment granule localization 1.160142e-3
GO:0046381 CMP-N-acetylneuraminate metabolic process 1.176541e-3
GO:0042254 ribosome biogenesis 1.329560e-3
GO:0050886 endocrine process 1.336682e-3
GO:0043201 response to leucine 1.368560e-3
GO:0071922 regulation of cohesin localization to chromatin 1.375465e-3
GO:0071635 negative regulation of transforming growth factor beta production 1.386255e-3
GO:0060896 neural plate pattern specification 1.386255e-3
GO:0006659 phosphatidylserine biosynthetic process 1.519035e-3
GO:0045749 negative regulation of S phase of mitotic cell cycle 1.564434e-3
GO:0016601 Rac protein signal transduction 1.665417e-3
GO:0007063 regulation of sister chromatid cohesion 1.699847e-3
GO:0010388 cullin deneddylation 1.699953e-3
GO:0008361 regulation of cell size 1.775884e-3
GO:0006379 mRNA cleavage 1.786265e-3
GO:0048148 behavioral response to cocaine 1.881709e-3
GO:0003127 detection of nodal flow 1.886994e-3
GO:0030500 regulation of bone mineralization 1.895174e-3
GO:0021602 cranial nerve morphogenesis 1.946140e-3
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 1.962062e-3
GO:0061387 regulation of extent of cell growth 2.155559e-3
GO:0045494 photoreceptor cell maintenance 2.244428e-3
GO:0006552 leucine catabolic process 2.269921e-3
GO:0031104 dendrite regeneration 2.269921e-3
GO:0045234 protein palmitoleylation 2.269921e-3
GO:0006948 induction by virus of host cell-cell fusion 2.269921e-3
GO:0048671 negative regulation of collateral sprouting 2.287244e-3
GO:0006096 glycolysis 2.315785e-3
GO:0032971 regulation of muscle filament sliding 2.366523e-3
GO:0090084 negative regulation of inclusion body assembly 2.413883e-3
GO:0070286 axonemal dynein complex assembly 2.413883e-3
GO:0021545 cranial nerve development 2.427980e-3
GO:0051310 metaphase plate congression 2.490106e-3
GO:0070167 regulation of biomineral tissue development 2.490152e-3
GO:0090305 nucleic acid phosphodiester bond hydrolysis 2.598531e-3
GO:0010460 positive regulation of heart rate 2.681853e-3
GO:0050808 synapse organization 2.683047e-3
GO:0001542 ovulation from ovarian follicle 2.715559e-3
GO:0060285 ciliary cell motility 2.742153e-3
GO:0002074 extraocular skeletal muscle development 2.742153e-3
GO:0031573 intra-S DNA damage checkpoint 2.752846e-3
GO:0048010 vascular endothelial growth factor receptor signaling pathway 2.844867e-3
GO:0010273 detoxification of copper ion 2.914959e-3
GO:0042701 progesterone secretion 3.009691e-3
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 3.099718e-3
GO:0032868 response to insulin stimulus 3.140155e-3
GO:0033148 positive regulation of estrogen receptor signaling pathway 3.283376e-3
GO:0003065 positive regulation of heart rate by epinephrine 3.283376e-3
GO:0015986 ATP synthesis coupled proton transport 3.307361e-3
GO:0040019 positive regulation of embryonic development 3.382855e-3
GO:0042396 phosphagen biosynthetic process 3.487802e-3
GO:0010833 telomere maintenance via telomere lengthening 3.487802e-3
GO:0006269 DNA replication, synthesis of RNA primer 3.487802e-3
GO:0006542 glutamine biosynthetic process 3.487802e-3
GO:0006406 mRNA export from nucleus 3.505841e-3
GO:0021570 rhombomere 4 development 3.535309e-3
GO:0021892 cerebral cortex GABAergic interneuron differentiation 3.536391e-3
GO:0006446 regulation of translational initiation 3.674911e-3
GO:0045213 neurotransmitter receptor metabolic process 3.739055e-3
GO:0060982 coronary artery morphogenesis 3.883697e-3
GO:0021853 cerebral cortex GABAergic interneuron migration 3.907602e-3
GO:0051303 establishment of chromosome localization 3.950414e-3
GO:0030262 apoptotic nuclear change 3.993393e-3
GO:0031442 positive regulation of mRNA 3'-end processing 4.202888e-3
GO:0050685 positive regulation of mRNA processing 4.204332e-3
GO:0006474 N-terminal protein amino acid acetylation 4.211543e-3
GO:0046813 virion attachment, binding of host cell surface receptor 4.230322e-3
GO:0042448 progesterone metabolic process 4.320892e-3
GO:0021796 cerebral cortex regionalization 4.360293e-3
GO:0045844 positive regulation of striated muscle tissue development 4.624828e-3
GO:0032413 negative regulation of ion transmembrane transporter activity 4.639008e-3
GO:0007413 axonal fasciculation 4.703162e-3
GO:0021564 vagus nerve development 4.767258e-3
GO:0060486 Clara cell differentiation 4.825862e-3
GO:0000082 G1/S transition of mitotic cell cycle 4.848848e-3
GO:0061338 atrioventricular node impulse conduction delay 4.887498e-3
GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 5.002492e-3
GO:0045807 positive regulation of endocytosis 5.045949e-3
GO:0060017 parathyroid gland development 5.313027e-3
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 5.368896e-3
GO:0046475 glycerophospholipid catabolic process 5.368896e-3
GO:0045039 protein import into mitochondrial inner membrane 5.368896e-3
GO:0046323 glucose import 5.368896e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 5.513594e-3
GO:0071600 otic vesicle morphogenesis 5.515417e-3
GO:0046339 diacylglycerol metabolic process 5.693181e-3
GO:2000121 regulation of removal of superoxide radicals 5.721480e-3
GO:0010501 RNA secondary structure unwinding 5.854079e-3
GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response 5.854079e-3
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 5.913108e-3
GO:0060033 anatomical structure regression 5.957241e-3
GO:0007368 determination of left/right symmetry 5.986206e-3
GO:0070327 thyroid hormone transport 6.151555e-3
GO:0006650 glycerophospholipid metabolic process 6.263172e-3
GO:0042438 melanin biosynthetic process 6.282875e-3
GO:0042255 ribosome assembly 6.282875e-3
GO:0006654 phosphatidic acid biosynthetic process 6.282875e-3
GO:0051180 vitamin transport 6.325364e-3
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 6.377071e-3
GO:0021843 substrate-independent telencephalic tangential interneuron migration 6.522412e-3
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 6.603829e-3
GO:0003062 regulation of heart rate by chemical signal 6.603829e-3
GO:0051329 interphase of mitotic cell cycle 6.697662e-3
GO:0003015 heart process 6.775973e-3
GO:0008380 RNA splicing 6.777028e-3
GO:0046168 glycerol-3-phosphate catabolic process 6.787112e-3
GO:0035880 embryonic nail plate morphogenesis 6.787112e-3
GO:0006658 phosphatidylserine metabolic process 6.794499e-3
GO:0006921 cellular component disassembly involved in apoptosis 6.837617e-3
GO:0045823 positive regulation of heart contraction 6.842977e-3
GO:0045955 negative regulation of calcium ion-dependent exocytosis 7.156125e-3
GO:0033119 negative regulation of RNA splicing 7.184855e-3
GO:0043501 skeletal muscle adaptation 7.251084e-3
GO:0031440 regulation of mRNA 3'-end processing 7.591152e-3
GO:0007064 mitotic sister chromatid cohesion 7.591152e-3
GO:0021559 trigeminal nerve development 7.591152e-3
GO:0032972 regulation of muscle filament sliding speed 7.637371e-3
GO:0001708 cell fate specification 7.639036e-3
GO:0009799 specification of symmetry 7.723016e-3
GO:0070474 positive regulation of uterine smooth muscle contraction 7.829132e-3
GO:0090287 regulation of cellular response to growth factor stimulus 7.902643e-3
GO:0030261 chromosome condensation 7.960088e-3
GO:0007617 mating behavior 8.012199e-3
GO:0048011 nerve growth factor receptor signaling pathway 8.099505e-3
GO:0048193 Golgi vesicle transport 8.108840e-3
GO:0016525 negative regulation of angiogenesis 8.176477e-3
GO:0051795 positive regulation of catagen 8.542385e-3
GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process 8.904551e-3
GO:0009225 nucleotide-sugar metabolic process 8.907861e-3
GO:0048818 positive regulation of hair follicle maturation 9.296797e-3
GO:0032912 negative regulation of transforming growth factor beta2 production 9.296797e-3
GO:0061337 cardiac conduction 9.512504e-3
GO:0048670 regulation of collateral sprouting 9.815016e-3
GO:0002027 regulation of heart rate 9.877738e-3
GO:0051325 interphase 9.959523e-3
GO:0071375 cellular response to peptide hormone stimulus 1.000230e-2
GO:0032938 negative regulation of translation in response to oxidative stress 1.005056e-2
GO:2001051 positive regulation of tendon cell differentiation 1.005056e-2
GO:0021509 roof plate formation 1.005056e-2
GO:0030578 PML body organization 1.005056e-2
GO:0000379 tRNA-type intron splice site recognition and cleavage 1.005056e-2
GO:0045014 negative regulation of transcription by glucose 1.009325e-2
GO:0003266 regulation of secondary heart field cardioblast proliferation 1.014593e-2
GO:0021783 preganglionic parasympathetic nervous system development 1.092413e-2
GO:0051567 histone H3-K9 methylation 1.108789e-2
GO:0048639 positive regulation of developmental growth 1.108814e-2
GO:0002009 morphogenesis of an epithelium 1.122038e-2
GO:0033762 response to glucagon stimulus 1.134143e-2
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 1.134143e-2
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 1.136686e-2
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 1.136686e-2
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 1.136686e-2
GO:0019062 virion attachment to host cell surface receptor 1.136686e-2
GO:0015872 dopamine transport 1.145702e-2
GO:0046532 regulation of photoreceptor cell differentiation 1.145702e-2
GO:0009084 glutamine family amino acid biosynthetic process 1.145702e-2
GO:0043954 cellular component maintenance 1.153643e-2
GO:0072337 modified amino acid transport 1.175861e-2
GO:0048708 astrocyte differentiation 1.191899e-2
GO:0051276 chromosome organization 1.192010e-2
GO:0001558 regulation of cell growth 1.195674e-2
GO:0030517 negative regulation of axon extension 1.219410e-2
GO:0030728 ovulation 1.244737e-2
GO:0072321 chaperone-mediated protein transport 1.273026e-2
GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development 1.273026e-2
GO:0006390 transcription from mitochondrial promoter 1.274305e-2
GO:0042843 D-xylose catabolic process 1.275417e-2
GO:0045684 positive regulation of epidermis development 1.275620e-2
GO:0030217 T cell differentiation 1.315199e-2
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 1.321106e-2
GO:0014821 phasic smooth muscle contraction 1.356002e-2
GO:0030278 regulation of ossification 1.366478e-2
GO:0003254 regulation of membrane depolarization 1.368780e-2
GO:0072348 sulfur compound transport 1.371568e-2
GO:2000008 regulation of protein localization at cell surface 1.371568e-2
GO:0030432 peristalsis 1.383523e-2
GO:0006405 RNA export from nucleus 1.390141e-2
GO:0072109 glomerular mesangium development 1.396167e-2
GO:0072061 inner medullary collecting duct development 1.418304e-2
GO:0072060 outer medullary collecting duct development 1.418304e-2
GO:2001037 positive regulation of tongue muscle cell differentiation 1.418304e-2
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 1.418304e-2
GO:0019405 alditol catabolic process 1.418304e-2
GO:0021644 vagus nerve morphogenesis 1.418304e-2
GO:0060428 lung epithelium development 1.436511e-2
GO:0051926 negative regulation of calcium ion transport 1.456473e-2
GO:0019067 viral assembly, maturation, egress, and release 1.475120e-2
GO:0048521 negative regulation of behavior 1.499753e-2
GO:0007613 memory 1.543549e-2
GO:0006582 melanin metabolic process 1.551394e-2
GO:0000723 telomere maintenance 1.555057e-2
GO:0031929 TOR signaling cascade 1.557006e-2
GO:0060048 cardiac muscle contraction 1.571167e-2
GO:0003051 angiotensin-mediated drinking behavior 1.572589e-2
GO:0051643 endoplasmic reticulum localization 1.572589e-2
GO:0071502 cellular response to temperature stimulus 1.573581e-2
GO:0048243 norepinephrine secretion 1.573581e-2
GO:0014827 intestine smooth muscle contraction 1.573581e-2
GO:0044275 cellular carbohydrate catabolic process 1.576267e-2
GO:0032869 cellular response to insulin stimulus 1.622792e-2
GO:0051209 release of sequestered calcium ion into cytosol 1.663977e-2
GO:0021515 cell differentiation in spinal cord 1.683818e-2
GO:0008050 female courtship behavior 1.691131e-2
GO:0048486 parasympathetic nervous system development 1.693746e-2
GO:0046782 regulation of viral transcription 1.720157e-2
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.735936e-2
GO:0048251 elastic fiber assembly 1.801628e-2
GO:0061113 pancreas morphogenesis 1.807114e-2
GO:0007221 positive regulation of transcription of Notch receptor target 1.807114e-2
GO:0032844 regulation of homeostatic process 1.874334e-2
GO:0048843 negative regulation of axon extension involved in axon guidance 1.878851e-2
GO:0051983 regulation of chromosome segregation 1.892060e-2
GO:0048857 neural nucleus development 1.892060e-2
GO:0071934 thiamine transmembrane transport 1.898350e-2
GO:0043420 anthranilate metabolic process 1.898350e-2
GO:0000053 argininosuccinate metabolic process 1.898350e-2
GO:0034516 response to vitamin B6 1.898350e-2
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.908383e-2
GO:0061298 retina vasculature development in camera-type eye 1.914710e-2
GO:0046533 negative regulation of photoreceptor cell differentiation 1.914710e-2
GO:0090083 regulation of inclusion body assembly 1.927919e-2
GO:0015991 ATP hydrolysis coupled proton transport 1.958062e-2
GO:0048483 autonomic nervous system development 1.966373e-2
GO:0070125 mitochondrial translational elongation 1.971326e-2
GO:0060562 epithelial tube morphogenesis 2.000368e-2
GO:0042053 regulation of dopamine metabolic process 2.011871e-2
GO:0014807 regulation of somitogenesis 2.089958e-2
GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 2.089958e-2
GO:0046784 intronless viral mRNA export from host nucleus 2.112200e-2
GO:0014823 response to activity 2.122248e-2
GO:0051937 catecholamine transport 2.143822e-2
GO:0032200 telomere organization 2.143822e-2
GO:0030837 negative regulation of actin filament polymerization 2.169952e-2
GO:0000959 mitochondrial RNA metabolic process 2.184192e-2
GO:0009914 hormone transport 2.206691e-2
GO:0033059 cellular pigmentation 2.231299e-2
GO:0006364 rRNA processing 2.232014e-2
GO:0018208 peptidyl-proline modification 2.233955e-2
GO:0019805 quinolinate biosynthetic process 2.248558e-2
GO:0000722 telomere maintenance via recombination 2.248558e-2
GO:0006278 RNA-dependent DNA replication 2.250966e-2
GO:0043374 CD8-positive, alpha-beta T cell differentiation 2.250966e-2
GO:0050771 negative regulation of axonogenesis 2.255651e-2
GO:0046174 polyol catabolic process 2.280670e-2
GO:0001732 formation of translation initiation complex 2.280670e-2
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation 2.298902e-2
GO:0000245 spliceosome assembly 2.329724e-2
GO:0030516 regulation of axon extension 2.343736e-2
GO:0046365 monosaccharide catabolic process 2.353402e-2
GO:0021675 nerve development 2.373826e-2
GO:0048255 mRNA stabilization 2.376466e-2
GO:0001711 endodermal cell fate commitment 2.380805e-2
GO:0045926 negative regulation of growth 2.414269e-2
GO:0010977 negative regulation of neuron projection development 2.446970e-2
GO:0051924 regulation of calcium ion transport 2.450386e-2
GO:0045065 cytotoxic T cell differentiation 2.460300e-2
GO:0007493 endodermal cell fate determination 2.460300e-2
GO:0048378 regulation of lateral mesodermal cell fate specification 2.480521e-2
GO:0006467 protein thiol-disulfide exchange 2.480521e-2
GO:0001306 age-dependent response to oxidative stress 2.480521e-2
GO:0016577 histone demethylation 2.506868e-2
GO:0000278 mitotic cell cycle 2.520335e-2
GO:0030513 positive regulation of BMP signaling pathway 2.527942e-2
GO:0010224 response to UV-B 2.543803e-2
GO:0003272 endocardial cushion formation 2.545851e-2
GO:0019637 organophosphate metabolic process 2.603603e-2
GO:2000791 negative regulation of mesenchymal cell proliferation involved in lung development 2.605884e-2
GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis 2.605884e-2
GO:0021740 principal sensory nucleus of trigeminal nerve development 2.605884e-2
GO:0061141 lung ciliated cell differentiation 2.605884e-2
GO:0042733 embryonic digit morphogenesis 2.620570e-2
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 2.623078e-2
GO:0061143 alveolar primary septum development 2.623078e-2
GO:0002897 positive regulation of central B cell tolerance induction 2.623078e-2
GO:0002508 central tolerance induction 2.623078e-2
GO:0050434 positive regulation of viral transcription 2.639827e-2
GO:0042069 regulation of catecholamine metabolic process 2.662501e-2
GO:0021978 telencephalon regionalization 2.662501e-2
GO:0071218 cellular response to misfolded protein 2.689497e-2
GO:0018119 peptidyl-cysteine S-nitrosylation 2.689497e-2
GO:0048608 reproductive structure development 2.709848e-2
GO:0045668 negative regulation of osteoblast differentiation 2.722530e-2
GO:0007411 axon guidance 2.726640e-2
GO:0010838 positive regulation of keratinocyte proliferation 2.756531e-2
GO:0007619 courtship behavior 2.756531e-2
GO:0005513 detection of calcium ion 2.756531e-2
GO:0071526 semaphorin-plexin signaling pathway 2.777767e-2
GO:0051968 positive regulation of synaptic transmission, glutamatergic 2.782737e-2
GO:0051282 regulation of sequestering of calcium ion 2.849292e-2
GO:0030900 forebrain development 2.857427e-2
GO:0021936 regulation of cerebellar granule cell precursor proliferation 2.880844e-2
GO:0090370 negative regulation of cholesterol efflux 2.907575e-2
GO:0042297 vocal learning 2.907575e-2
GO:0032902 nerve growth factor production 2.907575e-2
GO:0046015 regulation of transcription by glucose 2.912268e-2
GO:0007067 mitosis 2.939871e-2
GO:0060510 Type II pneumocyte differentiation 2.956462e-2
GO:0006882 cellular zinc ion homeostasis 2.984239e-2
GO:0085029 extracellular matrix assembly 2.986404e-2
GO:0048352 paraxial mesoderm structural organization 3.020815e-2
GO:0006433 prolyl-tRNA aminoacylation 3.020815e-2
GO:0021998 neural plate mediolateral regionalization 3.020815e-2
GO:0014874 response to stimulus involved in regulation of muscle adaptation 3.073117e-2
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3.091899e-2
GO:0006323 DNA packaging 3.155028e-2
GO:0007062 sister chromatid cohesion 3.156694e-2
GO:0006482 protein demethylation 3.156694e-2
GO:0042473 outer ear morphogenesis 3.162857e-2
GO:0034622 cellular macromolecular complex assembly 3.167311e-2
GO:0016072 rRNA metabolic process 3.199160e-2
GO:0009887 organ morphogenesis 3.209395e-2
GO:0071599 otic vesicle development 3.210419e-2
GO:0001503 ossification 3.226824e-2
GO:0006924 activation-induced cell death of T cells 3.239098e-2
GO:0035295 tube development 3.242131e-2
GO:0006261 DNA-dependent DNA replication 3.307259e-2
GO:0006644 phospholipid metabolic process 3.316702e-2
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 3.370885e-2
GO:0051612 negative regulation of serotonin uptake 3.370885e-2
GO:0042738 exogenous drug catabolic process 3.370885e-2
GO:0014732 skeletal muscle atrophy 3.410227e-2
GO:0060430 lung saccule development 3.433834e-2
GO:0030421 defecation 3.440710e-2
GO:0019442 tryptophan catabolic process to acetyl-CoA 3.440710e-2
GO:0006526 arginine biosynthetic process 3.440710e-2
GO:0018931 naphthalene metabolic process 3.440710e-2
GO:0007214 gamma-aminobutyric acid signaling pathway 3.473297e-2
GO:0006417 regulation of translation 3.486346e-2
GO:0022415 viral reproductive process 3.549523e-2
GO:0000087 M phase of mitotic cell cycle 3.555879e-2
GO:0048285 organelle fission 3.567061e-2
GO:0007512 adult heart development 3.571978e-2
GO:0055069 zinc ion homeostasis 3.577101e-2
GO:0008343 adult feeding behavior 3.586517e-2
GO:0021612 facial nerve structural organization 3.616019e-2
GO:0071400 cellular response to oleic acid 3.616019e-2
GO:0001840 neural plate development 3.718277e-2
GO:0071377 cellular response to glucagon stimulus 3.767977e-2
GO:0006600 creatine metabolic process 3.767977e-2
GO:0006007 glucose catabolic process 3.786774e-2
GO:2000179 positive regulation of neural precursor cell proliferation 3.847239e-2
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 3.859821e-2
GO:0072054 renal outer medulla development 3.870058e-2
GO:0001880 Mullerian duct regression 3.870058e-2
GO:0015805 S-adenosylmethionine transport 3.881736e-2
GO:0061146 Peyer's patch morphogenesis 3.903808e-2
GO:0001731 formation of translation preinitiation complex 3.903808e-2
GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development 3.903808e-2
GO:0072044 collecting duct development 3.922357e-2
GO:0002051 osteoblast fate commitment 3.954612e-2
GO:0001661 conditioned taste aversion 3.954612e-2
GO:0019058 viral infectious cycle 3.959244e-2
GO:0060271 cilium morphogenesis 3.973799e-2
GO:0051496 positive regulation of stress fiber assembly 3.974618e-2
GO:0010629 negative regulation of gene expression 3.991769e-2
GO:0048752 semicircular canal morphogenesis 4.012710e-2
GO:0000724 double-strand break repair via homologous recombination 4.060359e-2
GO:0030050 vesicle transport along actin filament 4.132928e-2
GO:0048268 clathrin coat assembly 4.171651e-2
GO:0003219 cardiac right ventricle formation 4.171651e-2
GO:0003310 pancreatic A cell differentiation 4.171651e-2
GO:0051918 negative regulation of fibrinolysis 4.182314e-2
GO:0006901 vesicle coating 4.329856e-2
GO:0002635 negative regulation of germinal center formation 4.342897e-2
GO:0046502 uroporphyrinogen III metabolic process 4.342897e-2
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 4.342897e-2
GO:0033590 response to cobalamin 4.342897e-2
GO:0045924 regulation of female receptivity 4.343417e-2
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 4.361145e-2
GO:0071285 cellular response to lithium ion 4.361145e-2
GO:0071158 positive regulation of cell cycle arrest 4.411467e-2
GO:0016338 calcium-independent cell-cell adhesion 4.481916e-2
GO:0010898 positive regulation of triglyceride catabolic process 4.491616e-2
GO:0007292 female gamete generation 4.536219e-2
GO:0001706 endoderm formation 4.544419e-2
GO:0007625 grooming behavior 4.545581e-2
GO:0071634 regulation of transforming growth factor beta production 4.584097e-2
GO:0047497 mitochondrion transport along microtubule 4.592131e-2
GO:0001843 neural tube closure 4.624222e-2
GO:0090304 nucleic acid metabolic process 4.636793e-2
GO:0002663 positive regulation of B cell tolerance induction 4.684839e-2