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Novel motif:162

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name:motif162_AGTTACCGTCA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0046032 ADP catabolic process 7.070157e-13
GO:0046709 IDP catabolic process 7.070157e-13
GO:0045214 sarcomere organization 1.404690e-11
GO:0043623 cellular protein complex assembly 8.274964e-11
GO:0060415 muscle tissue morphogenesis 2.548972e-10
GO:0055008 cardiac muscle tissue morphogenesis 2.992114e-10
GO:0048769 sarcomerogenesis 3.853452e-10
GO:0015942 formate metabolic process 4.062762e-10
GO:0009181 purine ribonucleoside diphosphate catabolic process 1.034238e-9
GO:0002684 positive regulation of immune system process 1.270045e-9
GO:0006941 striated muscle contraction 3.227687e-9
GO:0048739 cardiac muscle fiber development 3.937335e-9
GO:0072594 establishment of protein localization to organelle 3.987017e-9
GO:0048644 muscle organ morphogenesis 5.224720e-9
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 7.754340e-9
GO:0009396 folic acid-containing compound biosynthetic process 8.397293e-9
GO:0009191 ribonucleoside diphosphate catabolic process 1.291323e-8
GO:0032467 positive regulation of cytokinesis 1.532394e-8
GO:0048205 COPI coating of Golgi vesicle 1.944970e-8
GO:0071777 positive regulation of cell cycle cytokinesis 2.288180e-8
GO:0003278 apoptosis involved in heart morphogenesis 2.573269e-8
GO:0010288 response to lead ion 2.922320e-8
GO:0022600 digestive system process 3.080184e-8
GO:0030241 skeletal muscle myosin thick filament assembly 4.525886e-8
GO:0048194 Golgi vesicle budding 5.205280e-8
GO:0043032 positive regulation of macrophage activation 5.654194e-8
GO:0006955 immune response 6.575948e-8
GO:0010038 response to metal ion 6.657861e-8
GO:0034622 cellular macromolecular complex assembly 1.072969e-7
GO:0007076 mitotic chromosome condensation 1.374698e-7
GO:0030239 myofibril assembly 1.920382e-7
GO:0030240 skeletal muscle thin filament assembly 1.931611e-7
GO:0033690 positive regulation of osteoblast proliferation 2.319838e-7
GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I 2.334602e-7
GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent 2.334602e-7
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent 2.334602e-7
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent 2.334602e-7
GO:0051592 response to calcium ion 2.388413e-7
GO:0010927 cellular component assembly involved in morphogenesis 2.458361e-7
GO:2000505 regulation of energy homeostasis 2.862343e-7
GO:0022617 extracellular matrix disassembly 3.076501e-7
GO:0016558 protein import into peroxisome matrix 3.233605e-7
GO:0071800 podosome assembly 4.126065e-7
GO:0010759 positive regulation of macrophage chemotaxis 4.434998e-7
GO:0051649 establishment of localization in cell 4.599177e-7
GO:0031032 actomyosin structure organization 4.730288e-7
GO:0016064 immunoglobulin mediated immune response 4.961474e-7
GO:0071622 regulation of granulocyte chemotaxis 6.077843e-7
GO:0006457 protein folding 6.154242e-7
GO:0002576 platelet degranulation 6.418699e-7
GO:0010758 regulation of macrophage chemotaxis 7.194218e-7
GO:0009082 branched chain family amino acid biosynthetic process 7.280933e-7
GO:0006887 exocytosis 8.235726e-7
GO:0060164 regulation of timing of neuron differentiation 9.935507e-7
GO:0050892 intestinal absorption 1.035334e-6
GO:0002252 immune effector process 1.257163e-6
GO:0044267 cellular protein metabolic process 1.280095e-6
GO:0007586 digestion 1.319942e-6
GO:0043030 regulation of macrophage activation 1.353805e-6
GO:0006958 complement activation, classical pathway 1.353805e-6
GO:0032727 positive regulation of interferon-alpha production 1.601432e-6
GO:0071675 regulation of mononuclear cell migration 1.615039e-6
GO:0019724 B cell mediated immunity 1.900421e-6
GO:0006680 glucosylceramide catabolic process 1.924215e-6
GO:0070489 T cell aggregation 1.924215e-6
GO:0010623 developmental programmed cell death 1.935020e-6
GO:0002041 intussusceptive angiogenesis 1.967516e-6
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 2.204755e-6
GO:0055003 cardiac myofibril assembly 2.491755e-6
GO:2000304 positive regulation of ceramide biosynthetic process 2.768431e-6
GO:0002676 regulation of chronic inflammatory response 2.894872e-6
GO:0048747 muscle fiber development 3.340472e-6
GO:0010745 negative regulation of macrophage derived foam cell differentiation 3.615941e-6
GO:0048619 embryonic hindgut morphogenesis 3.849084e-6
GO:2000741 positive regulation of mesenchymal stem cell differentiation 4.027422e-6
GO:0006323 DNA packaging 4.084862e-6
GO:0007442 hindgut morphogenesis 4.568929e-6
GO:0032655 regulation of interleukin-12 production 4.881270e-6
GO:0023021 termination of signal transduction 5.030571e-6
GO:0002443 leukocyte mediated immunity 5.032504e-6
GO:2000303 regulation of ceramide biosynthetic process 5.859961e-6
GO:0019538 protein metabolic process 6.208263e-6
GO:0009083 branched chain family amino acid catabolic process 6.337626e-6
GO:0042559 pteridine-containing compound biosynthetic process 6.857917e-6
GO:0045321 leukocyte activation 7.380918e-6
GO:0061036 positive regulation of cartilage development 7.490146e-6
GO:0034621 cellular macromolecular complex subunit organization 7.993139e-6
GO:0007624 ultradian rhythm 8.565638e-6
GO:0046031 ADP metabolic process 9.344507e-6
GO:0010763 positive regulation of fibroblast migration 9.715898e-6
GO:2000507 positive regulation of energy homeostasis 1.047165e-5
GO:2000253 positive regulation of feeding behavior 1.047165e-5
GO:0032707 negative regulation of interleukin-23 production 1.154003e-5
GO:0002455 humoral immune response mediated by circulating immunoglobulin 1.262966e-5
GO:0006605 protein targeting 1.296204e-5
GO:0051641 cellular localization 1.304224e-5
GO:0030299 intestinal cholesterol absorption 1.470888e-5
GO:0014866 skeletal myofibril assembly 1.555243e-5
GO:0003007 heart morphogenesis 1.570056e-5
GO:0000070 mitotic sister chromatid segregation 1.689514e-5
GO:0002577 regulation of antigen processing and presentation 1.717361e-5
GO:0032891 negative regulation of organic acid transport 1.753250e-5
GO:0002449 lymphocyte mediated immunity 1.904067e-5
GO:0044282 small molecule catabolic process 1.912375e-5
GO:0045075 regulation of interleukin-12 biosynthetic process 1.930051e-5
GO:0003181 atrioventricular valve morphogenesis 2.011533e-5
GO:0055002 striated muscle cell development 2.178354e-5
GO:0046967 cytosol to ER transport 2.295309e-5
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.324771e-5
GO:0002475 antigen processing and presentation via MHC class Ib 2.516814e-5
GO:0060658 nipple morphogenesis 2.920403e-5
GO:0006956 complement activation 3.053030e-5
GO:0002696 positive regulation of leukocyte activation 3.150242e-5
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 3.503319e-5
GO:0006542 glutamine biosynthetic process 3.719281e-5
GO:0000819 sister chromatid segregation 3.730848e-5
GO:0001775 cell activation 3.731843e-5
GO:0019320 hexose catabolic process 3.751331e-5
GO:0090161 Golgi ribbon formation 3.876864e-5
GO:0002682 regulation of immune system process 3.909933e-5
GO:0046365 monosaccharide catabolic process 4.055343e-5
GO:0010754 negative regulation of cGMP-mediated signaling 4.233131e-5
GO:0043652 engulfment of apoptotic cell 4.233131e-5
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 4.233131e-5
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 4.233131e-5
GO:0010751 negative regulation of nitric oxide mediated signal transduction 4.233131e-5
GO:0046512 sphingosine biosynthetic process 4.322713e-5
GO:0060649 mammary gland bud elongation 4.383409e-5
GO:0060659 nipple sheath formation 4.383409e-5
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 4.551642e-5
GO:0045760 positive regulation of action potential 4.672595e-5
GO:2000739 regulation of mesenchymal stem cell differentiation 4.710283e-5
GO:0016446 somatic hypermutation of immunoglobulin genes 4.951801e-5
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 5.069579e-5
GO:0019438 aromatic compound biosynthetic process 5.182701e-5
GO:0030431 sleep 5.359329e-5
GO:0046514 ceramide catabolic process 5.677472e-5
GO:0032369 negative regulation of lipid transport 5.996433e-5
GO:0032914 positive regulation of transforming growth factor beta1 production 6.141596e-5
GO:0006952 defense response 6.207531e-5
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 6.467241e-5
GO:0009179 purine ribonucleoside diphosphate metabolic process 7.130243e-5
GO:0051712 positive regulation of killing of cells of other organism 7.519632e-5
GO:0072376 protein activation cascade 8.094936e-5
GO:0070271 protein complex biogenesis 8.460722e-5
GO:0019371 cyclooxygenase pathway 8.582684e-5
GO:0050746 regulation of lipoprotein metabolic process 9.349473e-5
GO:0055078 sodium ion homeostasis 9.411482e-5
GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase 9.543201e-5
GO:0035545 determination of left/right asymmetry in nervous system 9.762301e-5
GO:0030538 embryonic genitalia morphogenesis 9.776708e-5
GO:0043412 macromolecule modification 9.939307e-5
GO:0009593 detection of chemical stimulus 1.008816e-4
GO:0032425 positive regulation of mismatch repair 1.009963e-4
GO:0051877 pigment granule aggregation in cell center 1.028794e-4
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.054751e-4
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.054751e-4
GO:0016046 detection of fungus 1.054751e-4
GO:0016081 synaptic vesicle docking involved in exocytosis 1.072345e-4
GO:0050867 positive regulation of cell activation 1.078978e-4
GO:0006461 protein complex assembly 1.084483e-4
GO:0071403 cellular response to high density lipoprotein particle stimulus 1.097605e-4
GO:0071448 cellular response to alkyl hydroperoxide 1.097605e-4
GO:0031269 pseudopodium assembly 1.097605e-4
GO:0071315 cellular response to morphine 1.097605e-4
GO:0071307 cellular response to vitamin K 1.097605e-4
GO:0050904 diapedesis 1.097605e-4
GO:0009185 ribonucleoside diphosphate metabolic process 1.098702e-4
GO:0000413 protein peptidyl-prolyl isomerization 1.119034e-4
GO:0006464 protein modification process 1.134580e-4
GO:0045084 positive regulation of interleukin-12 biosynthetic process 1.154457e-4
GO:0048260 positive regulation of receptor-mediated endocytosis 1.183923e-4
GO:0006883 cellular sodium ion homeostasis 1.189593e-4
GO:0009081 branched chain family amino acid metabolic process 1.207814e-4
GO:0051258 protein polymerization 1.218851e-4
GO:0006954 inflammatory response 1.239693e-4
GO:0032465 regulation of cytokinesis 1.259968e-4
GO:0071103 DNA conformation change 1.274955e-4
GO:0010951 negative regulation of endopeptidase activity 1.301907e-4
GO:0006821 chloride transport 1.306685e-4
GO:0002678 positive regulation of chronic inflammatory response 1.307780e-4
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 1.318366e-4
GO:0045807 positive regulation of endocytosis 1.355723e-4
GO:0048245 eosinophil chemotaxis 1.359785e-4
GO:0060027 convergent extension involved in gastrulation 1.376319e-4
GO:0034613 cellular protein localization 1.411123e-4
GO:0007522 visceral muscle development 1.420798e-4
GO:0030048 actin filament-based movement 1.442886e-4
GO:0050776 regulation of immune response 1.470471e-4
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 1.525370e-4
GO:0046907 intracellular transport 1.572416e-4
GO:0006886 intracellular protein transport 1.576772e-4
GO:0065003 macromolecular complex assembly 1.578043e-4
GO:0050747 positive regulation of lipoprotein metabolic process 1.579204e-4
GO:0046968 peptide antigen transport 1.579204e-4
GO:0002281 macrophage activation involved in immune response 1.644616e-4
GO:0051606 detection of stimulus 1.727493e-4
GO:0051131 chaperone-mediated protein complex assembly 1.775096e-4
GO:0035234 germ cell programmed cell death 1.812229e-4
GO:0070727 cellular macromolecule localization 1.882339e-4
GO:0008634 negative regulation of survival gene product expression 1.904810e-4
GO:0046683 response to organophosphorus 1.929987e-4
GO:0033688 regulation of osteoblast proliferation 1.935658e-4
GO:0002251 organ or tissue specific immune response 1.944654e-4
GO:0002551 mast cell chemotaxis 2.003690e-4
GO:0046521 sphingoid catabolic process 2.042707e-4
GO:0045047 protein targeting to ER 2.070897e-4
GO:0006626 protein targeting to mitochondrion 2.076962e-4
GO:0042108 positive regulation of cytokine biosynthetic process 2.106110e-4
GO:0000117 regulation of transcription involved in G2/M-phase of mitotic cell cycle 2.152090e-4
GO:0030261 chromosome condensation 2.155413e-4
GO:0046653 tetrahydrofolate metabolic process 2.204255e-4
GO:0002426 immunoglobulin production in mucosal tissue 2.209987e-4
GO:0044356 clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine 2.278918e-4
GO:0042534 regulation of tumor necrosis factor biosynthetic process 2.335318e-4
GO:0048199 vesicle targeting, to, from or within Golgi 2.453650e-4
GO:0002376 immune system process 2.459047e-4
GO:0002706 regulation of lymphocyte mediated immunity 2.464682e-4
GO:0072358 cardiovascular system development 2.647060e-4
GO:0033632 regulation of cell-cell adhesion mediated by integrin 2.712389e-4
GO:0015805 S-adenosylmethionine transport 2.753261e-4
GO:0055001 muscle cell development 2.777660e-4
GO:0002819 regulation of adaptive immune response 2.794644e-4
GO:0048280 vesicle fusion with Golgi apparatus 2.804275e-4
GO:0071477 cellular hypotonic salinity response 2.871338e-4
GO:0052066 entry of symbiont into host cell by promotion of host phagocytosis 2.871338e-4
GO:0035635 entry of bacterium into host cell 2.871338e-4
GO:0051919 positive regulation of fibrinolysis 2.871338e-4
GO:0030049 muscle filament sliding 2.935119e-4
GO:0010666 positive regulation of cardiac muscle cell apoptosis 2.952244e-4
GO:0051650 establishment of vesicle localization 2.995556e-4
GO:0032695 negative regulation of interleukin-12 production 3.027463e-4
GO:0061035 regulation of cartilage development 3.069799e-4
GO:0003209 cardiac atrium morphogenesis 3.091669e-4
GO:0048259 regulation of receptor-mediated endocytosis 3.146540e-4
GO:0006625 protein targeting to peroxisome 3.173473e-4
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 3.433054e-4
GO:0060716 labyrinthine layer blood vessel development 3.486706e-4
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 3.521478e-4
GO:0031508 centromeric heterochromatin formation 3.578092e-4
GO:0046500 S-adenosylmethionine metabolic process 3.578103e-4
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 3.595538e-4
GO:0051246 regulation of protein metabolic process 3.638247e-4
GO:0044258 intestinal lipid catabolic process 3.680073e-4
GO:0018350 protein esterification 3.680073e-4
GO:0006259 DNA metabolic process 3.688222e-4
GO:0017085 response to insecticide 3.742232e-4
GO:0030277 maintenance of gastrointestinal epithelium 3.828743e-4
GO:0002385 mucosal immune response 3.848177e-4
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter 3.916238e-4
GO:0035459 cargo loading into vesicle 3.978028e-4
GO:0072393 microtubule anchoring at microtubule organizing center 3.989344e-4
GO:0060648 mammary gland bud morphogenesis 3.989344e-4
GO:0034112 positive regulation of homotypic cell-cell adhesion 3.993615e-4
GO:0010888 negative regulation of lipid storage 4.054296e-4
GO:0006007 glucose catabolic process 4.176697e-4
GO:0071593 lymphocyte aggregation 4.241921e-4
GO:2001054 negative regulation of mesenchymal cell apoptosis 4.413876e-4
GO:0055013 cardiac muscle cell development 4.420916e-4
GO:0009236 cobalamin biosynthetic process 4.581684e-4
GO:0070252 actin-mediated cell contraction 4.613592e-4
GO:0031268 pseudopodium organization 4.737721e-4
GO:0050778 positive regulation of immune response 4.776286e-4
GO:0006911 phagocytosis, engulfment 4.793005e-4
GO:0051917 regulation of fibrinolysis 4.806538e-4
GO:0090307 spindle assembly involved in mitosis 5.010762e-4
GO:0043574 peroxisomal transport 5.029681e-4
GO:0072593 reactive oxygen species metabolic process 5.330613e-4
GO:0071569 protein ufmylation 5.514531e-4
GO:0006760 folic acid-containing compound metabolic process 5.645039e-4
GO:0000082 G1/S transition of mitotic cell cycle 5.650817e-4
GO:0045727 positive regulation of translation 5.723597e-4
GO:0032940 secretion by cell 5.726132e-4
GO:0007173 epidermal growth factor receptor signaling pathway 5.857362e-4
GO:0006546 glycine catabolic process 5.967099e-4
GO:0046164 alcohol catabolic process 6.425074e-4
GO:0021544 subpallium development 6.436798e-4
GO:0032332 positive regulation of chondrocyte differentiation 6.462530e-4
GO:0002699 positive regulation of immune effector process 6.489547e-4
GO:0048505 regulation of timing of cell differentiation 6.514843e-4
GO:0072678 T cell migration 6.599043e-4
GO:0006953 acute-phase response 6.744164e-4
GO:0043405 regulation of MAP kinase activity 6.927605e-4
GO:0060674 placenta blood vessel development 6.947703e-4
GO:0002366 leukocyte activation involved in immune response 7.017620e-4
GO:0002694 regulation of leukocyte activation 7.162726e-4
GO:0060632 regulation of microtubule-based movement 7.285161e-4
GO:0000165 MAPKKK cascade 7.520815e-4
GO:0003230 cardiac atrium development 7.608170e-4
GO:0043537 negative regulation of blood vessel endothelial cell migration 7.762140e-4
GO:0002697 regulation of immune effector process 7.764692e-4
GO:0051412 response to corticosterone stimulus 7.829878e-4
GO:0015780 nucleotide-sugar transport 8.233932e-4
GO:0042035 regulation of cytokine biosynthetic process 8.321300e-4
GO:0006839 mitochondrial transport 8.423944e-4
GO:0001525 angiogenesis 8.648026e-4
GO:0042984 regulation of amyloid precursor protein biosynthetic process 8.705829e-4
GO:0006909 phagocytosis 8.741384e-4
GO:0002687 positive regulation of leukocyte migration 8.947771e-4
GO:0042119 neutrophil activation 8.987899e-4
GO:0046649 lymphocyte activation 9.219624e-4
GO:0002537 nitric oxide production involved in inflammatory response 9.372122e-4
GO:0006412 translation 9.627735e-4
GO:0055119 relaxation of cardiac muscle 9.632999e-4
GO:0051895 negative regulation of focal adhesion assembly 9.752051e-4
GO:0007031 peroxisome organization 9.782788e-4
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 9.800291e-4
GO:0080134 regulation of response to stress 9.821226e-4
GO:0002377 immunoglobulin production 9.851242e-4
GO:0051709 regulation of killing of cells of other organism 9.887986e-4
GO:0046395 carboxylic acid catabolic process 9.903750e-4
GO:0071353 cellular response to interleukin-4 1.004461e-3
GO:0046902 regulation of mitochondrial membrane permeability 1.004879e-3
GO:0017038 protein import 1.018926e-3
GO:0035518 histone H2A monoubiquitination 1.029577e-3
GO:0032908 regulation of transforming growth factor beta1 production 1.043545e-3
GO:0010466 negative regulation of peptidase activity 1.049087e-3
GO:0010661 positive regulation of muscle cell apoptosis 1.049248e-3
GO:0002200 somatic diversification of immune receptors 1.054524e-3
GO:0034446 substrate adhesion-dependent cell spreading 1.066142e-3
GO:0090005 negative regulation of establishment of protein localization in plasma membrane 1.093684e-3
GO:0032026 response to magnesium ion 1.111947e-3
GO:0032330 regulation of chondrocyte differentiation 1.141134e-3
GO:0070383 DNA cytosine deamination 1.145372e-3
GO:0070668 positive regulation of mast cell proliferation 1.167072e-3
GO:0043558 regulation of translational initiation in response to stress 1.170627e-3
GO:0034501 protein localization to kinetochore 1.170627e-3
GO:0006096 glycolysis 1.192653e-3
GO:0051648 vesicle localization 1.193851e-3
GO:0032423 regulation of mismatch repair 1.209975e-3
GO:0044241 lipid digestion 1.239248e-3
GO:0002250 adaptive immune response 1.240859e-3
GO:0060920 pacemaker cell differentiation 1.247495e-3
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.253548e-3
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.265539e-3
GO:2000425 regulation of apoptotic cell clearance 1.308845e-3
GO:0044068 modulation by symbiont of host cellular process 1.319937e-3
GO:0002253 activation of immune response 1.333185e-3
GO:0018208 peptidyl-proline modification 1.351373e-3
GO:0031341 regulation of cell killing 1.370069e-3
GO:0072655 establishment of protein localization in mitochondrion 1.386764e-3
GO:0006434 seryl-tRNA aminoacylation 1.391457e-3
GO:0045069 regulation of viral genome replication 1.394408e-3
GO:0071822 protein complex subunit organization 1.410438e-3
GO:0007005 mitochondrion organization 1.438558e-3
GO:0002709 regulation of T cell mediated immunity 1.441474e-3
GO:0002690 positive regulation of leukocyte chemotaxis 1.446256e-3
GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway 1.465429e-3
GO:0043933 macromolecular complex subunit organization 1.468707e-3
GO:0008298 intracellular mRNA localization 1.483366e-3
GO:0032647 regulation of interferon-alpha production 1.502078e-3
GO:0090197 positive regulation of chemokine secretion 1.506378e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1.506378e-3
GO:0060259 regulation of feeding behavior 1.507437e-3
GO:0048845 venous blood vessel morphogenesis 1.511857e-3
GO:0042450 arginine biosynthetic process via ornithine 1.517538e-3
GO:0006901 vesicle coating 1.530083e-3
GO:0002703 regulation of leukocyte mediated immunity 1.564291e-3
GO:0048285 organelle fission 1.568218e-3
GO:0051385 response to mineralocorticoid stimulus 1.577632e-3
GO:0042176 regulation of protein catabolic process 1.582680e-3
GO:0032890 regulation of organic acid transport 1.586043e-3
GO:0001816 cytokine production 1.588781e-3
GO:0008272 sulfate transport 1.608182e-3
GO:0044275 cellular carbohydrate catabolic process 1.615547e-3
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 1.623737e-3
GO:0031295 T cell costimulation 1.628159e-3
GO:0072385 minus-end-directed organelle transport along microtubule 1.651772e-3
GO:0045061 thymic T cell selection 1.659356e-3
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.662620e-3
GO:0031349 positive regulation of defense response 1.704695e-3
GO:0007018 microtubule-based movement 1.708231e-3
GO:0006891 intra-Golgi vesicle-mediated transport 1.715192e-3
GO:0055118 negative regulation of cardiac muscle contraction 1.735523e-3
GO:0006527 arginine catabolic process 1.735523e-3
GO:0002344 B cell affinity maturation 1.743285e-3
GO:0045039 protein import into mitochondrial inner membrane 1.778821e-3
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 1.778987e-3
GO:0019220 regulation of phosphate metabolic process 1.786384e-3
GO:0006099 tricarboxylic acid cycle 1.790380e-3
GO:0046483 heterocycle metabolic process 1.790430e-3
GO:0071636 positive regulation of transforming growth factor beta production 1.823766e-3
GO:0034655 nucleobase-containing compound catabolic process 1.839389e-3
GO:0033365 protein localization to organelle 1.844894e-3
GO:0051384 response to glucocorticoid stimulus 1.849600e-3
GO:0010955 negative regulation of protein processing 1.853233e-3
GO:0043536 positive regulation of blood vessel endothelial cell migration 1.905511e-3
GO:0030252 growth hormone secretion 1.922542e-3
GO:0046356 acetyl-CoA catabolic process 1.933266e-3
GO:0042663 regulation of endodermal cell fate specification 1.950159e-3
GO:0031343 positive regulation of cell killing 1.960300e-3
GO:0006084 acetyl-CoA metabolic process 1.973787e-3
GO:0060572 morphogenesis of an epithelial bud 2.016797e-3
GO:0070585 protein localization in mitochondrion 2.036158e-3
GO:0071361 cellular response to ethanol 2.046023e-3
GO:0032872 regulation of stress-activated MAPK cascade 2.092945e-3
GO:0002889 regulation of immunoglobulin mediated immune response 2.098360e-3
GO:0051918 negative regulation of fibrinolysis 2.111328e-3
GO:0045087 innate immune response 2.113605e-3
GO:0043653 mitochondrial fragmentation involved in apoptosis 2.152374e-3
GO:0030705 cytoskeleton-dependent intracellular transport 2.184742e-3
GO:0006687 glycosphingolipid metabolic process 2.188267e-3
GO:0006672 ceramide metabolic process 2.207232e-3
GO:0035606 peptidyl-cysteine S-trans-nitrosylation 2.227027e-3
GO:0043064 flagellum organization 2.299410e-3
GO:0002440 production of molecular mediator of immune response 2.324526e-3
GO:0060972 left/right pattern formation 2.331797e-3
GO:0060729 intestinal epithelial structure maintenance 2.331797e-3
GO:0051256 spindle midzone assembly involved in mitosis 2.369838e-3
GO:0002712 regulation of B cell mediated immunity 2.425806e-3
GO:0006730 one-carbon metabolic process 2.451695e-3
GO:0045006 DNA deamination 2.462946e-3
GO:0006458 'de novo' protein folding 2.484476e-3
GO:0016032 viral reproduction 2.495774e-3
GO:0010536 positive regulation of activation of Janus kinase activity 2.499069e-3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 2.499069e-3
GO:0018149 peptide cross-linking 2.522075e-3
GO:0003281 ventricular septum development 2.564246e-3
GO:0002274 myeloid leukocyte activation 2.614595e-3
GO:0050870 positive regulation of T cell activation 2.619105e-3
GO:0071560 cellular response to transforming growth factor beta stimulus 2.621429e-3
GO:0051084 'de novo' posttranslational protein folding 2.636005e-3
GO:0051881 regulation of mitochondrial membrane potential 2.677385e-3
GO:0045209 MAPK phosphatase export from nucleus, leptomycin B sensitive 2.714445e-3
GO:0045204 MAPK export from nucleus 2.714445e-3
GO:0048520 positive regulation of behavior 2.730307e-3
GO:0055010 ventricular cardiac muscle tissue morphogenesis 2.731607e-3
GO:0060009 Sertoli cell development 2.734537e-3
GO:0031347 regulation of defense response 2.766274e-3
GO:0010950 positive regulation of endopeptidase activity 2.770628e-3
GO:0048630 skeletal muscle tissue growth 2.773519e-3
GO:0007217 tachykinin receptor signaling pathway 2.773519e-3
GO:0002825 regulation of T-helper 1 type immune response 2.808338e-3
GO:0034605 cellular response to heat 2.835373e-3
GO:0015788 UDP-N-acetylglucosamine transport 2.867517e-3
GO:0035304 regulation of protein dephosphorylation 2.884900e-3
GO:0010035 response to inorganic substance 2.895412e-3
GO:0007507 heart development 2.909866e-3
GO:0090075 relaxation of muscle 2.924041e-3
GO:0010766 negative regulation of sodium ion transport 2.924041e-3
GO:0002831 regulation of response to biotic stimulus 2.954111e-3
GO:0032715 negative regulation of interleukin-6 production 2.973802e-3
GO:0072529 pyrimidine-containing compound catabolic process 3.035708e-3
GO:0010608 posttranscriptional regulation of gene expression 3.059990e-3
GO:0042116 macrophage activation 3.066808e-3
GO:0032103 positive regulation of response to external stimulus 3.107171e-3
GO:0046835 carbohydrate phosphorylation 3.113978e-3
GO:0015809 arginine transport 3.113978e-3
GO:0003222 ventricular trabecular myocardium morphogenesis 3.132384e-3
GO:0007006 mitochondrial membrane organization 3.142019e-3
GO:0032402 melanosome transport 3.219107e-3
GO:0048304 positive regulation of isotype switching to IgG isotypes 3.277227e-3
GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification 3.277227e-3
GO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3.277227e-3
GO:0048806 genitalia development 3.361434e-3
GO:0010529 negative regulation of transposition 3.364154e-3
GO:0043549 regulation of kinase activity 3.380737e-3
GO:0043666 regulation of phosphoprotein phosphatase activity 3.389033e-3
GO:0051897 positive regulation of protein kinase B signaling cascade 3.419984e-3
GO:0071476 cellular hypotonic response 3.517702e-3
GO:0001942 hair follicle development 3.523566e-3
GO:0060928 atrioventricular node cell development 3.581158e-3
GO:0060929 atrioventricular node cell fate commitment 3.581158e-3
GO:0003168 cardiac Purkinje fiber cell differentiation 3.581158e-3
GO:0034120 positive regulation of erythrocyte aggregation 3.581158e-3
GO:0006437 tyrosyl-tRNA aminoacylation 3.581158e-3
GO:0003342 proepicardium development 3.581158e-3
GO:0010757 negative regulation of plasminogen activation 3.590264e-3
GO:0042558 pteridine-containing compound metabolic process 3.595213e-3
GO:0009063 cellular amino acid catabolic process 3.635363e-3
GO:0008652 cellular amino acid biosynthetic process 3.650630e-3
GO:0032790 ribosome disassembly 3.672583e-3
GO:0034763 negative regulation of transmembrane transport 3.694146e-3
GO:0006020 inositol metabolic process 3.717496e-3
GO:0042633 hair cycle 3.891183e-3
GO:0006003 fructose 2,6-bisphosphate metabolic process 3.926540e-3
GO:0042325 regulation of phosphorylation 3.930995e-3
GO:0000266 mitochondrial fission 3.932334e-3
GO:0014823 response to activity 3.954765e-3
GO:0042297 vocal learning 3.979173e-3
GO:0071472 cellular response to salt stress 3.979173e-3
GO:0030070 insulin processing 3.979173e-3
GO:0006903 vesicle targeting 4.003451e-3
GO:0009164 nucleoside catabolic process 4.027522e-3
GO:0045650 negative regulation of macrophage differentiation 4.078462e-3
GO:0090224 regulation of spindle organization 4.155574e-3
GO:0006413 translational initiation 4.163984e-3
GO:0033153 T cell receptor V(D)J recombination 4.165160e-3
GO:0030187 melatonin biosynthetic process 4.276384e-3
GO:0001914 regulation of T cell mediated cytotoxicity 4.283985e-3
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 4.286268e-3
GO:0048514 blood vessel morphogenesis 4.339538e-3
GO:0002339 B cell selection 4.406323e-3
GO:0002821 positive regulation of adaptive immune response 4.455346e-3
GO:0032224 positive regulation of synaptic transmission, cholinergic 4.483921e-3
GO:0043271 negative regulation of ion transport 4.518654e-3
GO:0072091 regulation of stem cell proliferation 4.524300e-3
GO:0016048 detection of temperature stimulus 4.570057e-3
GO:0002826 negative regulation of T-helper 1 type immune response 4.570057e-3
GO:0045070 positive regulation of viral genome replication 4.637683e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 4.859150e-9
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 7.766737e-7
GO:0033382 maintenance of granzyme B location in T cell secretory granule 8.689332e-7
GO:0033373 maintenance of protease location in mast cell secretory granule 8.689332e-7
GO:0060154 cellular process regulating host cell cycle in response to virus 1.829995e-6
GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly 2.045537e-6
GO:0055013 cardiac muscle cell development 3.523379e-6
GO:0010955 negative regulation of protein processing 3.594206e-6
GO:0018149 peptide cross-linking 3.699412e-6
GO:0003350 pulmonary myocardium development 4.656760e-6
GO:0046373 L-arabinose metabolic process 4.979264e-6
GO:0043366 beta selection 6.361060e-6
GO:0019054 modulation by virus of host cellular process 6.538998e-6
GO:0032609 interferon-gamma production 6.582643e-6
GO:0006507 GPI anchor release 8.421886e-6
GO:0034097 response to cytokine stimulus 8.454378e-6
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 9.726181e-6
GO:0048668 collateral sprouting 1.019395e-5
GO:0090307 spindle assembly involved in mitosis 1.019395e-5
GO:0055006 cardiac cell development 1.157403e-5
GO:0031396 regulation of protein ubiquitination 1.241526e-5
GO:0031397 negative regulation of protein ubiquitination 1.276247e-5
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway 1.677114e-5
GO:0043056 forward locomotion 2.316209e-5
GO:0060658 nipple morphogenesis 2.772759e-5
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 3.025955e-5
GO:0051788 response to misfolded protein 3.132951e-5
GO:0071356 cellular response to tumor necrosis factor 3.147730e-5
GO:0008625 induction of apoptosis via death domain receptors 3.510478e-5
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 3.551852e-5
GO:0033364 mast cell secretory granule organization 3.620060e-5
GO:0061088 regulation of sequestering of zinc ion 3.720061e-5
GO:0045916 negative regulation of complement activation 3.733906e-5
GO:0006116 NADH oxidation 3.733906e-5
GO:0007099 centriole replication 4.286607e-5
GO:0034612 response to tumor necrosis factor 4.993235e-5
GO:0043543 protein acylation 5.736255e-5
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade 6.148426e-5
GO:0070613 regulation of protein processing 6.740652e-5
GO:0051310 metaphase plate congression 7.238794e-5
GO:0030204 chondroitin sulfate metabolic process 7.526950e-5
GO:0033363 secretory granule organization 8.112865e-5
GO:0031018 endocrine pancreas development 8.684494e-5
GO:0050869 negative regulation of B cell activation 9.078363e-5
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 1.012310e-4
GO:0033143 regulation of steroid hormone receptor signaling pathway 1.097731e-4
GO:0060537 muscle tissue development 1.138627e-4
GO:0006955 immune response 1.190209e-4
GO:0001869 negative regulation of complement activation, lectin pathway 1.199863e-4
GO:0007229 integrin-mediated signaling pathway 1.205873e-4
GO:0033058 directional locomotion 1.315716e-4
GO:0002921 negative regulation of humoral immune response 1.379364e-4
GO:0043137 DNA replication, removal of RNA primer 1.393850e-4
GO:0018364 peptidyl-glutamine methylation 1.393850e-4
GO:0046632 alpha-beta T cell differentiation 1.487993e-4
GO:2000078 positive regulation of type B pancreatic cell development 1.594900e-4
GO:0035928 rRNA import into mitochondrion 1.594900e-4
GO:0034139 regulation of toll-like receptor 3 signaling pathway 1.649458e-4
GO:0051303 establishment of chromosome localization 1.701284e-4
GO:0050654 chondroitin sulfate proteoglycan metabolic process 1.870269e-4
GO:0060841 venous blood vessel development 1.911426e-4
GO:0071345 cellular response to cytokine stimulus 1.916395e-4
GO:0046640 regulation of alpha-beta T cell proliferation 1.937875e-4
GO:0014706 striated muscle tissue development 1.939703e-4
GO:0030856 regulation of epithelial cell differentiation 1.978898e-4
GO:0010625 positive regulation of Schwann cell proliferation 2.022941e-4
GO:0043967 histone H4 acetylation 2.024094e-4
GO:0060427 lung connective tissue development 2.086044e-4
GO:0006278 RNA-dependent DNA replication 2.188977e-4
GO:0048213 Golgi vesicle prefusion complex stabilization 2.359051e-4
GO:0033209 tumor necrosis factor-mediated signaling pathway 2.544763e-4
GO:0050710 negative regulation of cytokine secretion 2.612194e-4
GO:0055003 cardiac myofibril assembly 2.693192e-4
GO:0008624 induction of apoptosis by extracellular signals 2.744623e-4
GO:0007080 mitotic metaphase plate congression 2.793210e-4
GO:0006273 lagging strand elongation 2.847092e-4
GO:0045579 positive regulation of B cell differentiation 2.929402e-4
GO:0046631 alpha-beta T cell activation 3.011267e-4
GO:0022007 convergent extension involved in neural plate elongation 3.052094e-4
GO:0006473 protein acetylation 3.251542e-4
GO:0045079 negative regulation of chemokine biosynthetic process 3.420639e-4
GO:0050821 protein stabilization 3.891984e-4
GO:0007144 female meiosis I 3.902791e-4
GO:0030449 regulation of complement activation 3.987431e-4
GO:0072259 metanephric interstitial cell development 4.143150e-4
GO:0072208 metanephric smooth muscle tissue development 4.143150e-4
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 4.143150e-4
GO:0072184 renal vesicle progenitor cell differentiation 4.143150e-4
GO:0072168 specification of anterior mesonephric tubule identity 4.143150e-4
GO:0072169 specification of posterior mesonephric tubule identity 4.143150e-4
GO:0002366 leukocyte activation involved in immune response 4.428746e-4
GO:0060174 limb bud formation 4.483807e-4
GO:0002281 macrophage activation involved in immune response 4.529460e-4
GO:0030388 fructose 1,6-bisphosphate metabolic process 4.726416e-4
GO:0007130 synaptonemal complex assembly 4.752205e-4
GO:0007340 acrosome reaction 5.179145e-4
GO:0071477 cellular hypotonic salinity response 5.229084e-4
GO:0072141 renal interstitial cell development 5.269014e-4
GO:0019221 cytokine-mediated signaling pathway 5.416633e-4
GO:0018193 peptidyl-amino acid modification 5.617164e-4
GO:0072608 interleukin-10 secretion 5.724153e-4
GO:0072643 interferon-gamma secretion 5.724153e-4
GO:0070963 positive regulation of neutrophil mediated killing of gram-negative bacterium 5.724153e-4
GO:0090198 negative regulation of chemokine secretion 5.724153e-4
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 5.724153e-4
GO:0035926 chemokine (C-C motif) ligand 2 secretion 5.724153e-4
GO:0043311 positive regulation of eosinophil degranulation 5.724153e-4
GO:0007155 cell adhesion 6.040736e-4
GO:0034501 protein localization to kinetochore 6.060630e-4
GO:0070071 proton-transporting two-sector ATPase complex assembly 6.079567e-4
GO:0035966 response to topologically incorrect protein 6.108158e-4
GO:0006022 aminoglycan metabolic process 6.108158e-4
GO:0046641 positive regulation of alpha-beta T cell proliferation 6.204037e-4
GO:0035372 protein localization to microtubule 6.240948e-4
GO:0050930 induction of positive chemotaxis 6.301357e-4
GO:0032462 regulation of protein homooligomerization 6.303616e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 6.567847e-4
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 6.576729e-4
GO:0045401 positive regulation of interleukin-3 biosynthetic process 6.576729e-4
GO:0009750 response to fructose stimulus 6.805977e-4
GO:0006434 seryl-tRNA aminoacylation 6.867327e-4
GO:0007094 mitotic cell cycle spindle assembly checkpoint 6.968437e-4
GO:0070536 protein K63-linked deubiquitination 7.025512e-4
GO:0003215 cardiac right ventricle morphogenesis 7.086570e-4
GO:0048840 otolith development 7.349789e-4
GO:0022407 regulation of cell-cell adhesion 7.538304e-4
GO:0022610 biological adhesion 7.787373e-4
GO:0051298 centrosome duplication 7.831550e-4
GO:0072190 ureter urothelium development 7.982572e-4
GO:0071174 mitotic cell cycle spindle checkpoint 7.982572e-4
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 8.017976e-4
GO:0060373 regulation of ventricular cardiomyocyte membrane depolarization 8.017976e-4
GO:0034227 tRNA thio-modification 8.017976e-4
GO:0061364 apoptosis involved in luteolysis 8.860910e-4
GO:0007040 lysosome organization 9.138433e-4
GO:0060554 induction of necroptosis of activated-T cells 9.167016e-4
GO:0042628 mating plug formation 1.003175e-3
GO:0006915 apoptosis 1.019162e-3
GO:0042110 T cell activation 1.026776e-3
GO:0002312 B cell activation involved in immune response 1.031230e-3
GO:0022408 negative regulation of cell-cell adhesion 1.042743e-3
GO:0042176 regulation of protein catabolic process 1.063954e-3
GO:0031016 pancreas development 1.077109e-3
GO:0045090 retroviral genome replication 1.111225e-3
GO:0071712 ER-associated misfolded protein catabolic process 1.125499e-3
GO:0006302 double-strand break repair 1.129004e-3
GO:0030502 negative regulation of bone mineralization 1.159247e-3
GO:0032011 ARF protein signal transduction 1.161993e-3
GO:0072573 tolerance induction to lipopolysaccharide 1.175341e-3
GO:2000349 negative regulation of CD40 signaling pathway 1.175341e-3
GO:0002632 negative regulation of granuloma formation 1.175341e-3
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.175341e-3
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.175341e-3
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 1.175341e-3
GO:0043367 CD4-positive, alpha-beta T cell differentiation 1.179120e-3
GO:0009566 fertilization 1.202178e-3
GO:0022010 central nervous system myelination 1.218438e-3
GO:0030203 glycosaminoglycan metabolic process 1.238425e-3
GO:0031400 negative regulation of protein modification process 1.254796e-3
GO:0072560 type B pancreatic cell maturation 1.282963e-3
GO:0051142 positive regulation of NK T cell proliferation 1.282963e-3
GO:0070168 negative regulation of biomineral tissue development 1.350125e-3
GO:0090005 negative regulation of establishment of protein localization in plasma membrane 1.382937e-3
GO:0070537 histone H2A K63-linked deubiquitination 1.382937e-3
GO:0006709 progesterone catabolic process 1.545983e-3
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 1.554899e-3
GO:0002507 tolerance induction 1.562468e-3
GO:0022409 positive regulation of cell-cell adhesion 1.650794e-3
GO:0034115 negative regulation of heterotypic cell-cell adhesion 1.662456e-3
GO:0035710 CD4-positive, alpha-beta T cell activation 1.665855e-3
GO:2000347 positive regulation of hepatocyte proliferation 1.682314e-3
GO:0032713 negative regulation of interleukin-4 production 1.708254e-3
GO:0018209 peptidyl-serine modification 1.728836e-3
GO:0006043 glucosamine catabolic process 1.740395e-3
GO:0071472 cellular response to salt stress 1.743234e-3
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity 1.743234e-3
GO:0007052 mitotic spindle organization 1.799502e-3
GO:0006260 DNA replication 1.815078e-3
GO:0032692 negative regulation of interleukin-1 production 1.822860e-3
GO:0005513 detection of calcium ion 1.885100e-3
GO:0007567 parturition 1.885100e-3
GO:2000657 negative regulation of apolipoprotein binding 1.887677e-3
GO:0048047 mating behavior, sex discrimination 1.887677e-3
GO:0001309 age-dependent telomere shortening 1.887677e-3
GO:0002124 territorial aggressive behavior 1.887677e-3
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway 1.887677e-3
GO:0002098 tRNA wobble uridine modification 1.919361e-3
GO:0046676 negative regulation of insulin secretion 1.986822e-3
GO:0016265 death 2.011414e-3
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 2.028686e-3
GO:0034383 low-density lipoprotein particle clearance 2.057397e-3
GO:0031348 negative regulation of defense response 2.057581e-3
GO:0090076 relaxation of skeletal muscle 2.106662e-3
GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 2.106662e-3
GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 2.106662e-3
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 2.106662e-3
GO:0045732 positive regulation of protein catabolic process 2.109137e-3
GO:0012501 programmed cell death 2.193574e-3
GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction 2.231103e-3
GO:0071777 positive regulation of cell cycle cytokinesis 2.234462e-3
GO:0000239 pachytene 2.286345e-3
GO:2000778 positive regulation of interleukin-6 secretion 2.299704e-3
GO:0007019 microtubule depolymerization 2.299704e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 2.348177e-3
GO:0033365 protein localization to organelle 2.393298e-3
GO:0019321 pentose metabolic process 2.397070e-3
GO:0042574 retinal metabolic process 2.456489e-3
GO:0030917 midbrain-hindbrain boundary development 2.501579e-3
GO:0051048 negative regulation of secretion 2.519731e-3
GO:0018393 internal peptidyl-lysine acetylation 2.527271e-3
GO:0043523 regulation of neuron apoptosis 2.543863e-3
GO:0022616 DNA strand elongation 2.578506e-3
GO:2000124 regulation of endocannabinoid signaling pathway 2.578506e-3
GO:0045321 leukocyte activation 2.581929e-3
GO:0007098 centrosome cycle 2.602011e-3
GO:0032463 negative regulation of protein homooligomerization 2.610852e-3
GO:0014819 regulation of skeletal muscle contraction 2.665665e-3
GO:0032094 response to food 2.710862e-3
GO:0018394 peptidyl-lysine acetylation 2.783240e-3
GO:0007519 skeletal muscle tissue development 2.851158e-3
GO:0043302 positive regulation of leukocyte degranulation 2.853385e-3
GO:0032817 regulation of natural killer cell proliferation 2.873743e-3
GO:0032465 regulation of cytokinesis 2.906614e-3
GO:2000256 positive regulation of male germ cell proliferation 2.931989e-3
GO:0042231 interleukin-13 biosynthetic process 2.931989e-3
GO:0090278 negative regulation of peptide hormone secretion 2.937478e-3
GO:0019853 L-ascorbic acid biosynthetic process 2.952859e-3
GO:0008219 cell death 2.968935e-3
GO:0005997 xylulose metabolic process 2.971369e-3
GO:0032691 negative regulation of interleukin-1 beta production 2.999562e-3
GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 3.000228e-3
GO:0070193 synaptonemal complex organization 3.000228e-3
GO:0002285 lymphocyte activation involved in immune response 3.023148e-3
GO:0071173 spindle assembly checkpoint 3.204655e-3
GO:2000348 regulation of CD40 signaling pathway 3.204655e-3
GO:0070936 protein K48-linked ubiquitination 3.255563e-3
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 3.278671e-3
GO:0050727 regulation of inflammatory response 3.375057e-3
GO:0060100 positive regulation of phagocytosis, engulfment 3.446701e-3
GO:0009586 rhodopsin mediated phototransduction 3.446701e-3
GO:0030879 mammary gland development 3.466085e-3
GO:0044003 modification by symbiont of host morphology or physiology 3.518200e-3
GO:0034122 negative regulation of toll-like receptor signaling pathway 3.577478e-3
GO:0046649 lymphocyte activation 3.596515e-3
GO:0001754 eye photoreceptor cell differentiation 3.613228e-3
GO:0032232 negative regulation of actin filament bundle assembly 3.667716e-3
GO:0045602 negative regulation of endothelial cell differentiation 3.670896e-3
GO:0072098 anterior/posterior pattern specification involved in kidney development 3.670896e-3
GO:0048389 intermediate mesoderm development 3.670896e-3
GO:0043402 glucocorticoid mediated signaling pathway 3.670896e-3
GO:0032425 positive regulation of mismatch repair 3.670896e-3
GO:0061113 pancreas morphogenesis 3.673283e-3
GO:0006475 internal protein amino acid acetylation 3.737598e-3
GO:0042095 interferon-gamma biosynthetic process 3.765551e-3
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 3.765551e-3
GO:0015889 cobalamin transport 3.765551e-3
GO:0072012 glomerulus vasculature development 3.831357e-3
GO:0045824 negative regulation of innate immune response 3.831357e-3
GO:0033085 negative regulation of T cell differentiation in thymus 3.840474e-3
GO:0042953 lipoprotein transport 3.861818e-3
GO:0002315 marginal zone B cell differentiation 3.898282e-3
GO:0010754 negative regulation of cGMP-mediated signaling 3.939741e-3
GO:0010751 negative regulation of nitric oxide mediated signal transduction 3.939741e-3
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 3.939741e-3
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 3.939741e-3
GO:0042759 long-chain fatty acid biosynthetic process 4.175570e-3
GO:0048478 replication fork protection 4.269684e-3
GO:0042851 L-alanine metabolic process 4.269684e-3
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 4.285826e-3
GO:0071476 cellular hypotonic response 4.325944e-3
GO:0001554 luteolysis 4.325944e-3
GO:0031122 cytoplasmic microtubule organization 4.381076e-3
GO:0003341 cilium movement 4.483070e-3
GO:0070059 apoptosis in response to endoplasmic reticulum stress 4.499691e-3
GO:0060965 negative regulation of gene silencing by miRNA 4.516415e-3
GO:0000244 assembly of spliceosomal tri-snRNP 4.516415e-3
GO:0019464 glycine decarboxylation via glycine cleavage system 4.516415e-3
GO:0034629 cellular protein complex localization 4.569565e-3
GO:0042098 T cell proliferation 4.629592e-3
GO:0097028 dendritic cell differentiation 4.692020e-3
GO:0000189 MAPK import into nucleus 4.692020e-3
GO:0072183 negative regulation of nephron tubule epithelial cell differentiation 4.692020e-3
GO:0060414 aorta smooth muscle tissue morphogenesis 4.702322e-3
GO:0048846 axon extension involved in axon guidance 4.702322e-3
GO:0060538 skeletal muscle organ development 4.716344e-3
GO:0042384 cilium assembly 4.728572e-3
GO:0060600 dichotomous subdivision of an epithelial terminal unit 4.734883e-3
GO:0003161 cardiac conduction system development 4.738285e-3
GO:0035413 positive regulation of catenin import into nucleus 4.928230e-3
GO:0070542 response to fatty acid 5.016745e-3
GO:2000275 regulation of oxidative phosphorylation uncoupler activity 5.060142e-3
GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry 5.060142e-3
GO:0071874 cellular response to norepinephrine stimulus 5.075088e-3
GO:0006528 asparagine metabolic process 5.075088e-3
GO:0048844 artery morphogenesis 5.075911e-3
GO:0010749 regulation of nitric oxide mediated signal transduction 5.079624e-3
GO:0032930 positive regulation of superoxide anion generation 5.079624e-3
GO:0009791 post-embryonic development 5.141303e-3
GO:0051561 elevation of mitochondrial calcium ion concentration 5.338715e-3
GO:0006505 GPI anchor metabolic process 5.438734e-3
GO:0032459 regulation of protein oligomerization 5.520578e-3
GO:0006029 proteoglycan metabolic process 5.620949e-3
GO:0031577 spindle checkpoint 5.627673e-3
GO:0043982 histone H4-K8 acetylation 5.732341e-3
GO:0043981 histone H4-K5 acetylation 5.732341e-3
GO:0030500 regulation of bone mineralization 5.739616e-3
GO:0046530 photoreceptor cell differentiation 5.742772e-3
GO:0060285 ciliary cell motility 5.878349e-3
GO:0032347 regulation of aldosterone biosynthetic process 5.878349e-3
GO:0043309 regulation of eosinophil degranulation 5.921986e-3
GO:0097029 mature dendritic cell differentiation 5.921986e-3
GO:0000079 regulation of cyclin-dependent protein kinase activity 6.000148e-3
GO:2000543 positive regulation of gastrulation 6.139314e-3
GO:0007635 chemosensory behavior 6.139314e-3
GO:0021903 rostrocaudal neural tube patterning 6.232556e-3
GO:0051276 chromosome organization 6.508845e-3
GO:0032467 positive regulation of cytokinesis 6.543766e-3
GO:0007160 cell-matrix adhesion 6.554402e-3
GO:0030217 T cell differentiation 6.588892e-3
GO:0035644 phosphoanandamide dephosphorylation 6.785340e-3
GO:0010757 negative regulation of plasminogen activation 6.844614e-3
GO:0030858 positive regulation of epithelial cell differentiation 6.882808e-3
GO:0050850 positive regulation of calcium-mediated signaling 6.965286e-3
GO:0009083 branched chain family amino acid catabolic process 6.970603e-3
GO:0032349 positive regulation of aldosterone biosynthetic process 6.978598e-3
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 7.082847e-3
GO:0060252 positive regulation of glial cell proliferation 7.217987e-3
GO:0043652 engulfment of apoptotic cell 7.217987e-3
GO:0070509 calcium ion import 7.250656e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 7.267574e-3
GO:0050709 negative regulation of protein secretion 7.306872e-3
GO:0045087 innate immune response 7.328704e-3
GO:0030521 androgen receptor signaling pathway 7.428382e-3
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 7.485145e-3
GO:0050810 regulation of steroid biosynthetic process 7.511360e-3
GO:0070933 histone H4 deacetylation 7.525331e-3
GO:0001556 oocyte maturation 7.620841e-3
GO:0055007 cardiac muscle cell differentiation 7.740462e-3
GO:0019236 response to pheromone 7.906191e-3
GO:0045190 isotype switching 7.957647e-3
GO:0035304 regulation of protein dephosphorylation 7.957647e-3
GO:0070167 regulation of biomineral tissue development 7.998664e-3
GO:0072162 metanephric mesenchymal cell differentiation 8.056729e-3
GO:0051029 rRNA transport 8.056729e-3
GO:0046898 response to cycloheximide 8.056729e-3
GO:0051224 negative regulation of protein transport 8.073386e-3
GO:0002634 regulation of germinal center formation 8.121379e-3
GO:0002011 morphogenesis of an epithelial sheet 8.148010e-3
GO:0051225 spindle assembly 8.177483e-3
GO:0045409 negative regulation of interleukin-6 biosynthetic process 8.254767e-3
GO:0010801 negative regulation of peptidyl-threonine phosphorylation 8.254767e-3
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 8.355797e-3
GO:0060426 lung vasculature development 8.362156e-3
GO:0045768 positive regulation of anti-apoptosis 8.408344e-3
GO:0055001 muscle cell development 8.424471e-3
GO:0007126 meiosis 8.447784e-3
GO:2000345 regulation of hepatocyte proliferation 8.545281e-3
GO:0031647 regulation of protein stability 8.621748e-3
GO:0006418 tRNA aminoacylation for protein translation 8.656005e-3
GO:0001988 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure 8.796925e-3
GO:0060112 generation of ovulation cycle rhythm 8.796925e-3
GO:0050864 regulation of B cell activation 8.805908e-3
GO:0002792 negative regulation of peptide secretion 8.872322e-3
GO:0071218 cellular response to misfolded protein 8.884227e-3
GO:0055069 zinc ion homeostasis 8.951210e-3
GO:0007129 synapsis 8.951210e-3
GO:0060931 sinoatrial node cell development 8.963242e-3
GO:0003167 atrioventricular bundle cell differentiation 8.963242e-3
GO:0034114 regulation of heterotypic cell-cell adhesion 8.998022e-3
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 8.998022e-3
GO:0070661 leukocyte proliferation 9.001873e-3
GO:0045767 regulation of anti-apoptosis 9.020395e-3
GO:0006270 DNA-dependent DNA replication initiation 9.034883e-3
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 9.034883e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 9.204764e-3
GO:0008228 opsonization 9.243745e-3
GO:0000226 microtubule cytoskeleton organization 9.740073e-3
GO:0043631 RNA polyadenylation 9.744810e-3
GO:0072239 metanephric glomerulus vasculature development 9.867628e-3
GO:0045217 cell-cell junction maintenance 9.867628e-3
GO:0046929 negative regulation of neurotransmitter secretion 9.899393e-3
GO:0043547 positive regulation of GTPase activity 9.910494e-3
GO:0002455 humoral immune response mediated by circulating immunoglobulin 9.957269e-3
GO:0035308 negative regulation of protein dephosphorylation 9.983849e-3
GO:0000012 single strand break repair 9.983849e-3
GO:0051583 dopamine uptake 1.008507e-2
GO:0090030 regulation of steroid hormone biosynthetic process 1.022813e-2
GO:0043134 regulation of hindgut contraction 1.023602e-2
GO:0032602 chemokine production 1.023602e-2
GO:0003417 growth plate cartilage development 1.027402e-2
GO:2000379 positive regulation of reactive oxygen species metabolic process 1.059918e-2
GO:0018205 peptidyl-lysine modification 1.061894e-2
GO:0072161 mesenchymal cell differentiation involved in kidney development 1.075494e-2
GO:0003323 type B pancreatic cell development 1.075494e-2
GO:0030223 neutrophil differentiation 1.075494e-2
GO:0034201 response to oleic acid 1.076702e-2
GO:0070192 chromosome organization involved in meiosis 1.093061e-2
GO:0016573 histone acetylation 1.093182e-2
GO:0007603 phototransduction, visible light 1.099082e-2
GO:0001955 blood vessel maturation 1.099082e-2
GO:0006917 induction of apoptosis 1.099842e-2
GO:0070925 organelle assembly 1.115124e-2
GO:0035909 aorta morphogenesis 1.128413e-2
GO:0090185 negative regulation of kidney development 1.139254e-2
GO:0021993 initiation of neural tube closure 1.139254e-2
GO:0042116 macrophage activation 1.147483e-2
GO:0042036 negative regulation of cytokine biosynthetic process 1.149278e-2
GO:0090179 planar cell polarity pathway involved in neural tube closure 1.159466e-2
GO:0071870 cellular response to catecholamine stimulus 1.159466e-2
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 1.159466e-2
GO:0072133 metanephric mesenchyme morphogenesis 1.161648e-2
GO:0019543 propionate catabolic process 1.161648e-2
GO:0050908 detection of light stimulus involved in visual perception 1.169872e-2
GO:0034143 regulation of toll-like receptor 4 signaling pathway 1.179529e-2
GO:0003007 heart morphogenesis 1.187841e-2
GO:0051321 meiotic cell cycle 1.208943e-2
GO:0000819 sister chromatid segregation 1.230519e-2
GO:0046685 response to arsenic-containing substance 1.233931e-2
GO:0090103 cochlea morphogenesis 1.246743e-2
GO:0012502 induction of programmed cell death 1.261028e-2
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 1.262598e-2
GO:2000178 negative regulation of neural precursor cell proliferation 1.268026e-2
GO:0020028 hemoglobin import 1.281072e-2
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.281072e-2
GO:0034135 regulation of toll-like receptor 2 signaling pathway 1.292194e-2
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 1.292194e-2
GO:0060376 positive regulation of mast cell differentiation 1.292194e-2
GO:0002508 central tolerance induction 1.292194e-2
GO:0009589 detection of UV 1.292194e-2
GO:0002897 positive regulation of central B cell tolerance induction 1.292194e-2
GO:0043535 regulation of blood vessel endothelial cell migration 1.303069e-2
GO:0045408 regulation of interleukin-6 biosynthetic process 1.315021e-2
GO:0021984 adenohypophysis development 1.315021e-2
GO:0001922 B-1 B cell homeostasis 1.315021e-2
GO:0006261 DNA-dependent DNA replication 1.317250e-2
GO:0007141 male meiosis I 1.338899e-2
GO:0009235 cobalamin metabolic process 1.351353e-2
GO:0006925 inflammatory cell apoptosis 1.351353e-2
GO:0030857 negative regulation of epithelial cell differentiation 1.368396e-2
GO:0070979 protein K11-linked ubiquitination 1.372451e-2
GO:0010755 regulation of plasminogen activation 1.376325e-2
GO:0009081 branched chain family amino acid metabolic process 1.386409e-2
GO:0071310 cellular response to organic substance 1.420016e-2
GO:0060580 ventral spinal cord interneuron fate determination 1.427993e-2
GO:0003327 type B pancreatic cell fate commitment 1.427993e-2
GO:0010884 positive regulation of lipid storage 1.433207e-2
GO:0060312 regulation of blood vessel remodeling 1.434349e-2
GO:0002698 negative regulation of immune effector process 1.445544e-2
GO:0016032 viral reproduction 1.452002e-2
GO:0021592 fourth ventricle development 1.460923e-2
GO:0002376 immune system process 1.475589e-2
GO:0060445 branching involved in salivary gland morphogenesis 1.477365e-2
GO:0010159 specification of organ position 1.488770e-2
GO:2000352 negative regulation of endothelial cell apoptosis 1.539936e-2
GO:0046666 retinal cell programmed cell death 1.559639e-2
GO:0033345 asparagine catabolic process via L-aspartate 1.559639e-2
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 1.559639e-2
GO:0006312 mitotic recombination 1.559639e-2
GO:0030330 DNA damage response, signal transduction by p53 class mediator 1.561313e-2
GO:0010470 regulation of gastrulation 1.574166e-2
GO:0019048 virus-host interaction 1.585573e-2
GO:0051248 negative regulation of protein metabolic process 1.594929e-2
GO:0071727 cellular response to triacyl bacterial lipopeptide 1.597145e-2
GO:0060971 embryonic heart tube left/right pattern formation 1.597145e-2
GO:0090045 positive regulation of deacetylase activity 1.597145e-2
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity 1.597145e-2
GO:0042495 detection of triacyl bacterial lipopeptide 1.597145e-2
GO:0042938 dipeptide transport 1.597145e-2
GO:0060921 sinoatrial node cell differentiation 1.597961e-2
GO:0047496 vesicle transport along microtubule 1.597961e-2
GO:0048294 negative regulation of isotype switching to IgE isotypes 1.607599e-2
GO:0043966 histone H3 acetylation 1.614535e-2
GO:0060134 prepulse inhibition 1.620969e-2
GO:0032673 regulation of interleukin-4 production 1.629867e-2
GO:0046488 phosphatidylinositol metabolic process 1.635253e-2
GO:0042035 regulation of cytokine biosynthetic process 1.644874e-2
GO:0001569 patterning of blood vessels 1.648391e-2
GO:0034121 regulation of toll-like receptor signaling pathway 1.661719e-2
GO:0090276 regulation of peptide hormone secretion 1.709140e-2
GO:0050796 regulation of insulin secretion 1.711640e-2
GO:0032101 regulation of response to external stimulus 1.715760e-2
GO:0046651 lymphocyte proliferation 1.725711e-2
GO:0018108 peptidyl-tyrosine phosphorylation 1.728644e-2
GO:0015937 coenzyme A biosynthetic process 1.732989e-2
GO:0072143 mesangial cell development 1.743622e-2
GO:0090273 regulation of somatostatin secretion 1.757233e-2
GO:0007262 STAT protein import into nucleus 1.757233e-2
GO:0071374 cellular response to parathyroid hormone stimulus 1.757233e-2
GO:2000172 regulation of branching morphogenesis of a nerve 1.776728e-2
GO:0030967 ER-nuclear sterol response pathway 1.776728e-2
GO:0010624 regulation of Schwann cell proliferation 1.776728e-2
GO:0019541 propionate metabolic process 1.787027e-2
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.790294e-2
GO:0019852 L-ascorbic acid metabolic process 1.820388e-2
GO:0050777 negative regulation of immune response 1.837119e-2
GO:0043687 post-translational protein modification 1.874986e-2
GO:0046825 regulation of protein export from nucleus 1.893370e-2
GO:0060926 pacemaker cell development 1.898136e-2
GO:0060932 His-Purkinje system cell differentiation 1.898136e-2
GO:0006474 N-terminal protein amino acid acetylation 1.898136e-2