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Novel motif:163

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name:motif163_GARTCGCCCTGTNA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0010883 regulation of lipid storage 2.098496e-18
GO:0010888 negative regulation of lipid storage 8.598906e-14
GO:0001300 chronological cell aging 2.511071e-13
GO:0010743 regulation of macrophage derived foam cell differentiation 7.182626e-12
GO:0010745 negative regulation of macrophage derived foam cell differentiation 1.427112e-10
GO:2000097 regulation of smooth muscle cell-matrix adhesion 1.257205e-9
GO:0046325 negative regulation of glucose import 3.511839e-9
GO:0045768 positive regulation of anti-apoptosis 5.755490e-9
GO:0070417 cellular response to cold 7.853407e-9
GO:0061043 regulation of vascular wound healing 9.080002e-9
GO:0035588 G-protein coupled purinergic receptor signaling pathway 1.365550e-8
GO:0061028 establishment of endothelial barrier 1.688381e-8
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion 2.156336e-8
GO:0071258 cellular response to gravity 2.156336e-8
GO:0061044 negative regulation of vascular wound healing 2.156336e-8
GO:0035491 positive regulation of leukotriene production involved in inflammatory response 2.156336e-8
GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway 3.255764e-8
GO:0031663 lipopolysaccharide-mediated signaling pathway 3.357470e-8
GO:0070059 apoptosis in response to endoplasmic reticulum stress 4.893041e-8
GO:0071222 cellular response to lipopolysaccharide 5.900277e-8
GO:0045767 regulation of anti-apoptosis 1.035842e-7
GO:0071219 cellular response to molecule of bacterial origin 1.050145e-7
GO:0035587 purinergic receptor signaling pathway 1.159670e-7
GO:0009220 pyrimidine ribonucleotide biosynthetic process 2.007621e-7
GO:0010466 negative regulation of peptidase activity 2.920921e-7
GO:0032495 response to muramyl dipeptide 2.950545e-7
GO:0010884 positive regulation of lipid storage 3.355404e-7
GO:0060401 cytosolic calcium ion transport 3.708470e-7
GO:0009218 pyrimidine ribonucleotide metabolic process 3.991630e-7
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 4.152494e-7
GO:0071216 cellular response to biotic stimulus 8.240227e-7
GO:0032769 negative regulation of monooxygenase activity 8.367996e-7
GO:0032496 response to lipopolysaccharide 1.051001e-6
GO:0006767 water-soluble vitamin metabolic process 1.086466e-6
GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 1.113591e-6
GO:0006222 UMP biosynthetic process 1.115052e-6
GO:0050852 T cell receptor signaling pathway 1.139699e-6
GO:0052547 regulation of peptidase activity 1.179395e-6
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter 1.676836e-6
GO:0006916 anti-apoptosis 1.756098e-6
GO:0032494 response to peptidoglycan 1.804153e-6
GO:0046131 pyrimidine ribonucleoside metabolic process 1.822863e-6
GO:0048685 negative regulation of collateral sprouting of intact axon in response to injury 1.889898e-6
GO:0033629 negative regulation of cell adhesion mediated by integrin 1.924331e-6
GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1.979539e-6
GO:0009116 nucleoside metabolic process 2.460488e-6
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 2.482518e-6
GO:0050748 negative regulation of lipoprotein metabolic process 2.772920e-6
GO:0051707 response to other organism 2.946473e-6
GO:0042246 tissue regeneration 3.005885e-6
GO:0060027 convergent extension involved in gastrulation 3.197752e-6
GO:0050775 positive regulation of dendrite morphogenesis 3.265954e-6
GO:0051354 negative regulation of oxidoreductase activity 3.690916e-6
GO:0060928 atrioventricular node cell development 3.768840e-6
GO:0060929 atrioventricular node cell fate commitment 3.768840e-6
GO:0003342 proepicardium development 3.768840e-6
GO:0003168 cardiac Purkinje fiber cell differentiation 3.768840e-6
GO:0051904 pigment granule transport 3.951809e-6
GO:0032402 melanosome transport 4.097848e-6
GO:0006359 regulation of transcription from RNA polymerase III promoter 4.107273e-6
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 4.155254e-6
GO:0007605 sensory perception of sound 4.568052e-6
GO:0002237 response to molecule of bacterial origin 4.905917e-6
GO:0022002 negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway 4.963322e-6
GO:0048263 determination of dorsal identity 4.963322e-6
GO:0055014 atrial cardiac muscle cell development 5.165691e-6
GO:0007286 spermatid development 6.046848e-6
GO:0031953 negative regulation of protein autophosphorylation 6.558535e-6
GO:0009607 response to biotic stimulus 6.631349e-6
GO:0051384 response to glucocorticoid stimulus 6.732722e-6
GO:0009615 response to virus 7.011873e-6
GO:0006213 pyrimidine nucleoside metabolic process 7.179464e-6
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 7.405071e-6
GO:0055093 response to hyperoxia 7.665710e-6
GO:0043900 regulation of multi-organism process 8.507733e-6
GO:0051877 pigment granule aggregation in cell center 8.703200e-6
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 9.804932e-6
GO:0002429 immune response-activating cell surface receptor signaling pathway 9.928493e-6
GO:0042424 catecholamine catabolic process 1.026668e-5
GO:0003222 ventricular trabecular myocardium morphogenesis 1.065275e-5
GO:0006221 pyrimidine nucleotide biosynthetic process 1.065495e-5
GO:0051346 negative regulation of hydrolase activity 1.140031e-5
GO:0010038 response to metal ion 1.218568e-5
GO:0048515 spermatid differentiation 1.319561e-5
GO:0060402 calcium ion transport into cytosol 1.370798e-5
GO:0050851 antigen receptor-mediated signaling pathway 1.383245e-5
GO:0031960 response to corticosteroid stimulus 1.687377e-5
GO:0060556 regulation of vitamin D biosynthetic process 1.721844e-5
GO:0070874 negative regulation of glycogen metabolic process 1.742934e-5
GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus 1.750953e-5
GO:0051385 response to mineralocorticoid stimulus 1.771154e-5
GO:0033619 membrane protein proteolysis 1.855285e-5
GO:0051875 pigment granule localization 1.858915e-5
GO:0032102 negative regulation of response to external stimulus 1.865440e-5
GO:0050954 sensory perception of mechanical stimulus 1.925899e-5
GO:0016576 histone dephosphorylation 1.980267e-5
GO:0030538 embryonic genitalia morphogenesis 2.078673e-5
GO:0010886 positive regulation of cholesterol storage 2.115921e-5
GO:0032400 melanosome localization 2.124086e-5
GO:0060632 regulation of microtubule-based movement 2.167951e-5
GO:0001885 endothelial cell development 2.191261e-5
GO:0046847 filopodium assembly 2.230851e-5
GO:0061041 regulation of wound healing 2.313270e-5
GO:0006554 lysine catabolic process 2.377902e-5
GO:0002768 immune response-regulating cell surface receptor signaling pathway 2.416749e-5
GO:0060920 pacemaker cell differentiation 2.428866e-5
GO:0060971 embryonic heart tube left/right pattern formation 2.428866e-5
GO:0043973 histone H3-K4 acetylation 2.452503e-5
GO:0046985 positive regulation of hemoglobin biosynthetic process 2.452503e-5
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 2.452503e-5
GO:0007181 transforming growth factor beta receptor complex assembly 2.555308e-5
GO:0030035 microspike assembly 2.577704e-5
GO:0021756 striatum development 3.061410e-5
GO:0051282 regulation of sequestering of calcium ion 3.090416e-5
GO:0031284 positive regulation of guanylate cyclase activity 3.119611e-5
GO:0071674 mononuclear cell migration 3.119611e-5
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade 3.137579e-5
GO:0051905 establishment of pigment granule localization 3.165640e-5
GO:0003278 apoptosis involved in heart morphogenesis 3.224443e-5
GO:0009726 detection of endogenous stimulus 3.228971e-5
GO:0050685 positive regulation of mRNA processing 3.411958e-5
GO:0032401 establishment of melanosome localization 3.556863e-5
GO:0045719 negative regulation of glycogen biosynthetic process 3.671494e-5
GO:0019413 acetate biosynthetic process 3.745469e-5
GO:0019542 propionate biosynthetic process 3.745469e-5
GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus 4.054352e-5
GO:0051209 release of sequestered calcium ion into cytosol 4.078494e-5
GO:0021881 Wnt receptor signaling pathway involved in forebrain neuron fate commitment 4.107673e-5
GO:0030031 cell projection assembly 4.226315e-5
GO:0002253 activation of immune response 4.347704e-5
GO:0044205 'de novo' UMP biosynthetic process 4.435126e-5
GO:0051900 regulation of mitochondrial depolarization 4.578128e-5
GO:0035058 nonmotile primary cilium assembly 4.585777e-5
GO:0033239 negative regulation of cellular amine metabolic process 4.628974e-5
GO:0009629 response to gravity 4.640704e-5
GO:0061014 positive regulation of mRNA catabolic process 4.732438e-5
GO:0035590 purinergic nucleotide receptor signaling pathway 4.761951e-5
GO:0051591 response to cAMP 4.787222e-5
GO:0010713 negative regulation of collagen metabolic process 5.022733e-5
GO:0046951 ketone body biosynthetic process 5.407258e-5
GO:0010829 negative regulation of glucose transport 5.625697e-5
GO:0009617 response to bacterium 5.792991e-5
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway 5.866910e-5
GO:0051656 establishment of organelle localization 6.357665e-5
GO:0003127 detection of nodal flow 6.762400e-5
GO:0009855 determination of bilateral symmetry 7.320006e-5
GO:0042976 activation of Janus kinase activity 7.607692e-5
GO:0032049 cardiolipin biosynthetic process 7.630849e-5
GO:0010044 response to aluminum ion 7.747820e-5
GO:0010033 response to organic substance 7.753848e-5
GO:0043627 response to estrogen stimulus 8.130414e-5
GO:0090308 regulation of methylation-dependent chromatin silencing 8.738021e-5
GO:0051704 multi-organism process 8.766203e-5
GO:0051258 protein polymerization 8.851154e-5
GO:0009124 nucleoside monophosphate biosynthetic process 8.874556e-5
GO:0006509 membrane protein ectodomain proteolysis 9.241391e-5
GO:0006540 glutamate decarboxylation to succinate 9.561161e-5
GO:0030970 retrograde protein transport, ER to cytosol 9.740168e-5
GO:0032374 regulation of cholesterol transport 1.011994e-4
GO:0007253 cytoplasmic sequestering of NF-kappaB 1.017324e-4
GO:0010288 response to lead ion 1.070319e-4
GO:0043086 negative regulation of catalytic activity 1.072614e-4
GO:0022009 central nervous system vasculogenesis 1.106447e-4
GO:0051902 negative regulation of mitochondrial depolarization 1.120902e-4
GO:0070483 detection of hypoxia 1.181249e-4
GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity 1.192031e-4
GO:0033059 cellular pigmentation 1.194878e-4
GO:0031442 positive regulation of mRNA 3'-end processing 1.202429e-4
GO:0050688 regulation of defense response to virus 1.227085e-4
GO:0046950 cellular ketone body metabolic process 1.269914e-4
GO:0021544 subpallium development 1.270540e-4
GO:0009799 specification of symmetry 1.294295e-4
GO:0032369 negative regulation of lipid transport 1.417802e-4
GO:0048262 determination of dorsal/ventral asymmetry 1.419049e-4
GO:0032606 type I interferon production 1.477292e-4
GO:0032088 negative regulation of NF-kappaB transcription factor activity 1.484894e-4
GO:0010875 positive regulation of cholesterol efflux 1.488177e-4
GO:0003254 regulation of membrane depolarization 1.488177e-4
GO:0001101 response to acid 1.595222e-4
GO:0071625 vocalization behavior 1.615059e-4
GO:0034135 regulation of toll-like receptor 2 signaling pathway 1.621789e-4
GO:0072528 pyrimidine-containing compound biosynthetic process 1.664611e-4
GO:0009296 flagellum assembly 1.694996e-4
GO:0032692 negative regulation of interleukin-1 production 1.788635e-4
GO:0042136 neurotransmitter biosynthetic process 1.816103e-4
GO:0048545 response to steroid hormone stimulus 1.831423e-4
GO:0009719 response to endogenous stimulus 1.833502e-4
GO:0045760 positive regulation of action potential 1.857716e-4
GO:0051568 histone H3-K4 methylation 1.896206e-4
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 1.938918e-4
GO:0042221 response to chemical stimulus 1.973528e-4
GO:0032368 regulation of lipid transport 1.977417e-4
GO:0051131 chaperone-mediated protein complex assembly 1.998598e-4
GO:0006959 humoral immune response 2.046941e-4
GO:0002831 regulation of response to biotic stimulus 2.055095e-4
GO:0016339 calcium-dependent cell-cell adhesion 2.142857e-4
GO:0050668 positive regulation of homocysteine metabolic process 2.300467e-4
GO:0045963 negative regulation of dopamine metabolic process 2.300467e-4
GO:0016311 dephosphorylation 2.349384e-4
GO:0009119 ribonucleoside metabolic process 2.421074e-4
GO:0006517 protein deglycosylation 2.421998e-4
GO:0042981 regulation of apoptosis 2.457336e-4
GO:0009123 nucleoside monophosphate metabolic process 2.457623e-4
GO:0045909 positive regulation of vasodilation 2.493960e-4
GO:0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction 2.559925e-4
GO:0040007 growth 2.571881e-4
GO:0051001 negative regulation of nitric-oxide synthase activity 2.577602e-4
GO:0010885 regulation of cholesterol storage 2.633474e-4
GO:0033240 positive regulation of cellular amine metabolic process 2.644979e-4
GO:0061003 positive regulation of dendritic spine morphogenesis 2.700791e-4
GO:0002861 regulation of inflammatory response to antigenic stimulus 2.738397e-4
GO:0042133 neurotransmitter metabolic process 2.770749e-4
GO:0051797 regulation of hair follicle development 2.806258e-4
GO:0046952 ketone body catabolic process 2.894220e-4
GO:0015755 fructose transport 2.967371e-4
GO:0014826 vein smooth muscle contraction 2.985042e-4
GO:0006940 regulation of smooth muscle contraction 3.049870e-4
GO:0014909 smooth muscle cell migration 3.068603e-4
GO:0016081 synaptic vesicle docking involved in exocytosis 3.081957e-4
GO:0048260 positive regulation of receptor-mediated endocytosis 3.083761e-4
GO:0032376 positive regulation of cholesterol transport 3.115736e-4
GO:0060841 venous blood vessel development 3.128621e-4
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 3.162291e-4
GO:0002536 respiratory burst involved in inflammatory response 3.234656e-4
GO:0051176 positive regulation of sulfur metabolic process 3.281699e-4
GO:0060972 left/right pattern formation 3.335240e-4
GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity 3.335278e-4
GO:0048518 positive regulation of biological process 3.336154e-4
GO:0060923 cardiac muscle cell fate commitment 3.412695e-4
GO:0052548 regulation of endopeptidase activity 3.490476e-4
GO:0046324 regulation of glucose import 3.572550e-4
GO:0022617 extracellular matrix disassembly 3.603427e-4
GO:0018352 protein-pyridoxal-5-phosphate linkage 3.606804e-4
GO:0009068 aspartate family amino acid catabolic process 3.773917e-4
GO:0035507 regulation of myosin-light-chain-phosphatase activity 3.875610e-4
GO:0043375 CD8-positive, alpha-beta T cell lineage commitment 3.875610e-4
GO:0032848 negative regulation of cellular pH reduction 3.875610e-4
GO:0021747 cochlear nucleus development 3.875610e-4
GO:0010447 response to acidity 3.875610e-4
GO:0014042 positive regulation of neuron maturation 3.875610e-4
GO:0030212 hyaluronan metabolic process 3.918738e-4
GO:0002678 positive regulation of chronic inflammatory response 3.918738e-4
GO:0043067 regulation of programmed cell death 3.937409e-4
GO:0051051 negative regulation of transport 3.988294e-4
GO:0032691 negative regulation of interleukin-1 beta production 3.998650e-4
GO:0021570 rhombomere 4 development 4.004361e-4
GO:0006542 glutamine biosynthetic process 4.156540e-4
GO:0021546 rhombomere development 4.241878e-4
GO:0042762 regulation of sulfur metabolic process 4.327879e-4
GO:0003058 hormonal regulation of the force of heart contraction 4.351900e-4
GO:0060311 negative regulation of elastin catabolic process 4.429928e-4
GO:0010711 negative regulation of collagen catabolic process 4.429928e-4
GO:0060313 negative regulation of blood vessel remodeling 4.429928e-4
GO:0010703 negative regulation of histolysis 4.429928e-4
GO:0002765 immune response-inhibiting signal transduction 4.429928e-4
GO:0002826 negative regulation of T-helper 1 type immune response 4.438450e-4
GO:0007569 cell aging 4.452423e-4
GO:0042634 regulation of hair cycle 4.626359e-4
GO:0015993 molecular hydrogen transport 4.626851e-4
GO:0009156 ribonucleoside monophosphate biosynthetic process 4.650036e-4
GO:0090310 negative regulation of methylation-dependent chromatin silencing 4.676723e-4
GO:0010889 regulation of sequestering of triglyceride 4.693691e-4
GO:0061013 regulation of mRNA catabolic process 4.810140e-4
GO:0035635 entry of bacterium into host cell 4.977400e-4
GO:0052066 entry of symbiont into host cell by promotion of host phagocytosis 4.977400e-4
GO:0046984 regulation of hemoglobin biosynthetic process 4.977400e-4
GO:0003100 regulation of systemic arterial blood pressure by endothelin 5.025958e-4
GO:0097117 guanylate kinase-associated protein clustering 5.066742e-4
GO:0097114 N-methyl-D-aspartate receptor clustering 5.066742e-4
GO:0048683 regulation of collateral sprouting of intact axon in response to injury 5.066742e-4
GO:0097112 gamma-aminobutyric acid receptor clustering 5.066742e-4
GO:0050778 positive regulation of immune response 5.068181e-4
GO:0045471 response to ethanol 5.163649e-4
GO:0014824 artery smooth muscle contraction 5.172201e-4
GO:0010735 positive regulation of transcription via serum response element binding 5.214836e-4
GO:0000060 protein import into nucleus, translocation 5.310904e-4
GO:0043623 cellular protein complex assembly 5.392214e-4
GO:0030195 negative regulation of blood coagulation 5.407632e-4
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 5.437739e-4
GO:0030643 cellular phosphate ion homeostasis 5.701675e-4
GO:0045638 negative regulation of myeloid cell differentiation 5.870190e-4
GO:0007157 heterophilic cell-cell adhesion 5.875366e-4
GO:0050666 regulation of homocysteine metabolic process 5.929838e-4
GO:0001808 negative regulation of type IV hypersensitivity 5.929838e-4
GO:0002684 positive regulation of immune system process 5.994495e-4
GO:0048012 hepatocyte growth factor receptor signaling pathway 6.069889e-4
GO:0070350 regulation of white fat cell proliferation 6.181490e-4
GO:0032101 regulation of response to external stimulus 6.278796e-4
GO:0070278 extracellular matrix constituent secretion 6.295822e-4
GO:0010260 organ senescence 6.295822e-4
GO:0051094 positive regulation of developmental process 6.389747e-4
GO:0051412 response to corticosterone stimulus 6.471627e-4
GO:0006808 regulation of nitrogen utilization 6.542555e-4
GO:0009310 amine catabolic process 6.557545e-4
GO:0008228 opsonization 6.573862e-4
GO:0007214 gamma-aminobutyric acid signaling pathway 6.573862e-4
GO:0048566 embryonic digestive tract development 6.576999e-4
GO:0002690 positive regulation of leukocyte chemotaxis 6.608628e-4
GO:0045930 negative regulation of mitotic cell cycle 7.011579e-4
GO:0001973 adenosine receptor signaling pathway 7.209335e-4
GO:0031282 regulation of guanylate cyclase activity 7.259837e-4
GO:0032355 response to estradiol stimulus 7.278008e-4
GO:0051956 negative regulation of amino acid transport 7.284720e-4
GO:0034139 regulation of toll-like receptor 3 signaling pathway 7.502455e-4
GO:0061048 negative regulation of branching involved in lung morphogenesis 7.599550e-4
GO:0033688 regulation of osteoblast proliferation 7.690585e-4
GO:0008653 lipopolysaccharide metabolic process 7.690585e-4
GO:0090023 positive regulation of neutrophil chemotaxis 7.734591e-4
GO:0001807 regulation of type IV hypersensitivity 7.780397e-4
GO:0007584 response to nutrient 7.823904e-4
GO:0006888 ER to Golgi vesicle-mediated transport 8.056264e-4
GO:0032753 positive regulation of interleukin-4 production 8.140400e-4
GO:0009725 response to hormone stimulus 8.211389e-4
GO:0043064 flagellum organization 8.227811e-4
GO:0030505 inorganic diphosphate transport 8.240012e-4
GO:0000187 activation of MAPK activity 8.256005e-4
GO:0045083 negative regulation of interleukin-12 biosynthetic process 8.351760e-4
GO:0070904 transepithelial L-ascorbic acid transport 8.351760e-4
GO:0043570 maintenance of DNA repeat elements 8.584871e-4
GO:0002064 epithelial cell development 8.597332e-4
GO:0007174 epidermal growth factor catabolic process 8.643611e-4
GO:0007207 activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway 8.677210e-4
GO:0009888 tissue development 8.757297e-4
GO:0048536 spleen development 8.844483e-4
GO:0044092 negative regulation of molecular function 8.864460e-4
GO:0050746 regulation of lipoprotein metabolic process 8.938594e-4
GO:0010744 positive regulation of macrophage derived foam cell differentiation 9.012912e-4
GO:0014912 negative regulation of smooth muscle cell migration 9.013214e-4
GO:0051953 negative regulation of amine transport 9.038327e-4
GO:0034371 chylomicron remodeling 9.256156e-4
GO:0042730 fibrinolysis 9.461334e-4
GO:0002326 B cell lineage commitment 9.490854e-4
GO:0045823 positive regulation of heart contraction 9.751012e-4
GO:0010243 response to organic nitrogen 9.913080e-4
GO:0042994 cytoplasmic sequestering of transcription factor 9.917353e-4
GO:0006642 triglyceride mobilization 9.962507e-4
GO:0030193 regulation of blood coagulation 1.034995e-3
GO:0006457 protein folding 1.044637e-3
GO:0051648 vesicle localization 1.065126e-3
GO:2000347 positive regulation of hepatocyte proliferation 1.071384e-3
GO:2000349 negative regulation of CD40 signaling pathway 1.071384e-3
GO:0090291 negative regulation of osteoclast proliferation 1.071384e-3
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.071384e-3
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 1.071384e-3
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.071384e-3
GO:0072573 tolerance induction to lipopolysaccharide 1.071384e-3
GO:0042420 dopamine catabolic process 1.089912e-3
GO:0002688 regulation of leukocyte chemotaxis 1.093416e-3
GO:0009161 ribonucleoside monophosphate metabolic process 1.096511e-3
GO:0071285 cellular response to lithium ion 1.101447e-3
GO:0090026 positive regulation of monocyte chemotaxis 1.109296e-3
GO:0042312 regulation of vasodilation 1.115540e-3
GO:0010035 response to inorganic substance 1.132281e-3
GO:0032891 negative regulation of organic acid transport 1.139880e-3
GO:0048857 neural nucleus development 1.140965e-3
GO:0045596 negative regulation of cell differentiation 1.145249e-3
GO:0043330 response to exogenous dsRNA 1.149889e-3
GO:0010874 regulation of cholesterol efflux 1.149889e-3
GO:0050690 regulation of defense response to virus by virus 1.157553e-3
GO:0010957 negative regulation of vitamin D biosynthetic process 1.192304e-3
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 1.200366e-3
GO:0045872 positive regulation of rhodopsin gene expression 1.203804e-3
GO:0002462 tolerance induction to nonself antigen 1.203804e-3
GO:0051092 positive regulation of NF-kappaB transcription factor activity 1.204065e-3
GO:0050853 B cell receptor signaling pathway 1.214119e-3
GO:0051650 establishment of vesicle localization 1.232613e-3
GO:0070318 positive regulation of G0 to G1 transition 1.236823e-3
GO:0032879 regulation of localization 1.246491e-3
GO:0006508 proteolysis 1.247639e-3
GO:0060409 positive regulation of acetylcholine metabolic process 1.272787e-3
GO:0006220 pyrimidine nucleotide metabolic process 1.281856e-3
GO:0007568 aging 1.311941e-3
GO:0002832 negative regulation of response to biotic stimulus 1.327808e-3
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.344458e-3
GO:0010941 regulation of cell death 1.358160e-3
GO:0071888 macrophage apoptosis 1.364160e-3
GO:0040023 establishment of nucleus localization 1.428014e-3
GO:0002764 immune response-regulating signaling pathway 1.435733e-3
GO:0009304 tRNA transcription 1.436556e-3
GO:0048845 venous blood vessel morphogenesis 1.437752e-3
GO:0014812 muscle cell migration 1.437752e-3
GO:0046134 pyrimidine nucleoside biosynthetic process 1.450274e-3
GO:0006538 glutamate catabolic process 1.469602e-3
GO:0031109 microtubule polymerization or depolymerization 1.473513e-3
GO:0014910 regulation of smooth muscle cell migration 1.477570e-3
GO:0042493 response to drug 1.487814e-3
GO:0007281 germ cell development 1.511997e-3
GO:0019220 regulation of phosphate metabolic process 1.557271e-3
GO:0042135 neurotransmitter catabolic process 1.561723e-3
GO:0070316 regulation of G0 to G1 transition 1.582115e-3
GO:0010890 positive regulation of sequestering of triglyceride 1.582115e-3
GO:0060137 maternal process involved in parturition 1.590342e-3
GO:0008219 cell death 1.611811e-3
GO:0050803 regulation of synapse structure and activity 1.616162e-3
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA 1.633338e-3
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 1.633825e-3
GO:0048619 embryonic hindgut morphogenesis 1.689398e-3
GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 1.742380e-3
GO:0010956 negative regulation of calcidiol 1-monooxygenase activity 1.742380e-3
GO:0001504 neurotransmitter uptake 1.750976e-3
GO:0016265 death 1.768135e-3
GO:0016198 axon choice point recognition 1.777526e-3
GO:0042977 activation of JAK2 kinase activity 1.812427e-3
GO:0007368 determination of left/right symmetry 1.848701e-3
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 1.870161e-3
GO:0072527 pyrimidine-containing compound metabolic process 1.887626e-3
GO:0034059 response to anoxia 1.902902e-3
GO:0000082 G1/S transition of mitotic cell cycle 1.934426e-3
GO:0006766 vitamin metabolic process 1.993892e-3
GO:0002862 negative regulation of inflammatory response to antigenic stimulus 1.999552e-3
GO:0045994 positive regulation of translational initiation by iron 2.006295e-3
GO:0002037 negative regulation of L-glutamate transport 2.006295e-3
GO:0050819 negative regulation of coagulation 2.021753e-3
GO:0006310 DNA recombination 2.036128e-3
GO:0045749 negative regulation of S phase of mitotic cell cycle 2.050117e-3
GO:0042325 regulation of phosphorylation 2.063198e-3
GO:0046796 viral genome transport in host cell 2.065148e-3
GO:0051798 positive regulation of hair follicle development 2.102863e-3
GO:0021999 neural plate anterior/posterior regionalization 2.115936e-3
GO:0061036 positive regulation of cartilage development 2.148300e-3
GO:0050684 regulation of mRNA processing 2.176082e-3
GO:0045351 type I interferon biosynthetic process 2.216338e-3
GO:0042797 tRNA transcription from RNA polymerase III promoter 2.216338e-3
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 2.216338e-3
GO:2000379 positive regulation of reactive oxygen species metabolic process 2.226336e-3
GO:0034625 fatty acid elongation, monounsaturated fatty acid 2.238413e-3
GO:0048522 positive regulation of cellular process 2.251635e-3
GO:0034763 negative regulation of transmembrane transport 2.273612e-3
GO:0097118 neuroligin clustering 2.276567e-3
GO:0051341 regulation of oxidoreductase activity 2.296498e-3
GO:0045597 positive regulation of cell differentiation 2.303816e-3
GO:0019216 regulation of lipid metabolic process 2.309338e-3
GO:0080111 DNA demethylation 2.347730e-3
GO:0035729 cellular response to hepatocyte growth factor stimulus 2.347730e-3
GO:0071803 positive regulation of podosome assembly 2.351874e-3
GO:0032886 regulation of microtubule-based process 2.435888e-3
GO:0072321 chaperone-mediated protein transport 2.443493e-3
GO:0051293 establishment of spindle localization 2.448569e-3
GO:0042347 negative regulation of NF-kappaB import into nucleus 2.483117e-3
GO:0002687 positive regulation of leukocyte migration 2.510115e-3
GO:0010701 positive regulation of norepinephrine secretion 2.571576e-3
GO:0001881 receptor recycling 2.571576e-3
GO:0043473 pigmentation 2.588139e-3
GO:0002757 immune response-activating signal transduction 2.605362e-3
GO:0042157 lipoprotein metabolic process 2.625216e-3
GO:0080134 regulation of response to stress 2.655198e-3
GO:0060999 positive regulation of dendritic spine development 2.664365e-3
GO:0060557 positive regulation of vitamin D biosynthetic process 2.668292e-3
GO:0034122 negative regulation of toll-like receptor signaling pathway 2.693301e-3
GO:0006915 apoptosis 2.695157e-3
GO:0032847 regulation of cellular pH reduction 2.706972e-3
GO:0010561 negative regulation of glycoprotein biosynthetic process 2.706972e-3
GO:0048585 negative regulation of response to stimulus 2.743858e-3
GO:0008628 induction of apoptosis by hormones 2.782908e-3
GO:0048016 inositol phosphate-mediated signaling 2.802161e-3
GO:0033574 response to testosterone stimulus 2.820390e-3
GO:0034104 negative regulation of tissue remodeling 2.828138e-3
GO:0032966 negative regulation of collagen biosynthetic process 2.835802e-3
GO:0061046 regulation of branching involved in lung morphogenesis 2.838849e-3
GO:0032754 positive regulation of interleukin-5 production 2.838849e-3
GO:2000739 regulation of mesenchymal stem cell differentiation 2.864664e-3
GO:2000116 regulation of cysteine-type endopeptidase activity 2.890495e-3
GO:2000348 regulation of CD40 signaling pathway 2.950190e-3
GO:0031440 regulation of mRNA 3'-end processing 2.950190e-3
GO:0018095 protein polyglutamylation 2.981594e-3
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 2.981594e-3
GO:0032703 negative regulation of interleukin-2 production 2.996067e-3
GO:0051093 negative regulation of developmental process 3.000550e-3
GO:0002676 regulation of chronic inflammatory response 3.005120e-3
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 3.005120e-3
GO:0001662 behavioral fear response 3.008170e-3
GO:0003285 septum secundum development 3.016364e-3
GO:0002669 positive regulation of T cell anergy 3.050670e-3
GO:0060911 cardiac cell fate commitment 3.050670e-3
GO:0021612 facial nerve structural organization 3.091237e-3
GO:0045646 regulation of erythrocyte differentiation 3.095863e-3
GO:0048589 developmental growth 3.112370e-3
GO:2000021 regulation of ion homeostasis 3.121786e-3
GO:0043368 positive T cell selection 3.158545e-3
GO:0070827 chromatin maintenance 3.170931e-3
GO:0035946 mitochondrial mRNA surveillance 3.170931e-3
GO:0035945 mitochondrial ncRNA surveillance 3.170931e-3
GO:0010741 negative regulation of intracellular protein kinase cascade 3.180321e-3
GO:0002360 T cell lineage commitment 3.182668e-3
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 3.200043e-3
GO:0032924 activin receptor signaling pathway 3.283393e-3
GO:0014821 phasic smooth muscle contraction 3.284934e-3
GO:0031532 actin cytoskeleton reorganization 3.293679e-3
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 3.318947e-3
GO:0012501 programmed cell death 3.349603e-3
GO:0010757 negative regulation of plasminogen activation 3.361748e-3
GO:0044254 multicellular organismal protein catabolic process 3.398095e-3
GO:0015891 siderophore transport 3.398095e-3
GO:0032375 negative regulation of cholesterol transport 3.469535e-3
GO:0030509 BMP signaling pathway 3.470947e-3
GO:0046685 response to arsenic-containing substance 3.492158e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 3.497529e-3
GO:0071391 cellular response to estrogen stimulus 3.533744e-3
GO:0015914 phospholipid transport 3.534197e-3
GO:0002682 regulation of immune system process 3.540074e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 2.874225e-16
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.588537e-14
GO:0045796 negative regulation of intestinal cholesterol absorption 3.937400e-13
GO:0010949 negative regulation of intestinal phytosterol absorption 3.937400e-13
GO:0060457 negative regulation of digestive system process 1.884222e-11
GO:0042116 macrophage activation 3.957262e-11
GO:0002579 positive regulation of antigen processing and presentation 9.015978e-11
GO:0002577 regulation of antigen processing and presentation 2.251892e-10
GO:0060008 Sertoli cell differentiation 1.379052e-9
GO:0009123 nucleoside monophosphate metabolic process 1.864066e-9
GO:0015809 arginine transport 2.483611e-9
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 2.732852e-9
GO:0046058 cAMP metabolic process 3.525485e-9
GO:0043252 sodium-independent organic anion transport 3.627879e-9
GO:0060009 Sertoli cell development 4.267603e-9
GO:0072539 T-helper 17 cell differentiation 2.468452e-8
GO:0072521 purine-containing compound metabolic process 5.235791e-8
GO:0032680 regulation of tumor necrosis factor production 5.831112e-8
GO:0006163 purine nucleotide metabolic process 6.061354e-8
GO:0009187 cyclic nucleotide metabolic process 6.083760e-8
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 7.372938e-8
GO:0050862 positive regulation of T cell receptor signaling pathway 1.462357e-7
GO:0035752 lysosomal lumen pH elevation 1.978780e-7
GO:0001575 globoside metabolic process 1.978780e-7
GO:0000046 autophagic vacuole fusion 1.978780e-7
GO:0002720 positive regulation of cytokine production involved in immune response 2.546777e-7
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 3.178211e-7
GO:0045582 positive regulation of T cell differentiation 4.384055e-7
GO:0071361 cellular response to ethanol 5.730686e-7
GO:0060491 regulation of cell projection assembly 5.773812e-7
GO:0051489 regulation of filopodium assembly 5.946311e-7
GO:0002688 regulation of leukocyte chemotaxis 6.467703e-7
GO:0045919 positive regulation of cytolysis 6.646775e-7
GO:0051491 positive regulation of filopodium assembly 7.206193e-7
GO:0032743 positive regulation of interleukin-2 production 7.566982e-7
GO:0019374 galactolipid metabolic process 7.606491e-7
GO:0002675 positive regulation of acute inflammatory response 8.631987e-7
GO:0044058 regulation of digestive system process 9.429936e-7
GO:0044281 small molecule metabolic process 1.101931e-6
GO:0009117 nucleotide metabolic process 1.132925e-6
GO:0002699 positive regulation of immune effector process 1.208243e-6
GO:0002355 detection of tumor cell 1.413337e-6
GO:0002885 positive regulation of hypersensitivity 1.621011e-6
GO:0030595 leukocyte chemotaxis 1.683269e-6
GO:0055086 nucleobase-containing small molecule metabolic process 1.704263e-6
GO:0045621 positive regulation of lymphocyte differentiation 1.734738e-6
GO:0015939 pantothenate metabolic process 1.819736e-6
GO:0030299 intestinal cholesterol absorption 1.920288e-6
GO:0051454 intracellular pH elevation 1.951850e-6
GO:0016242 negative regulation of macroautophagy 2.001805e-6
GO:0002347 response to tumor cell 2.001805e-6
GO:0015802 basic amino acid transport 2.058801e-6
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 2.144748e-6
GO:0031330 negative regulation of cellular catabolic process 2.187783e-6
GO:0002685 regulation of leukocyte migration 2.675936e-6
GO:0016241 regulation of macroautophagy 2.687826e-6
GO:0032760 positive regulation of tumor necrosis factor production 2.718760e-6
GO:0046700 heterocycle catabolic process 3.101020e-6
GO:0030593 neutrophil chemotaxis 3.113955e-6
GO:0042228 interleukin-8 biosynthetic process 4.694503e-6
GO:0033077 T cell differentiation in thymus 5.240616e-6
GO:0001817 regulation of cytokine production 5.821074e-6
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 6.082016e-6
GO:0035691 macrophage migration inhibitory factor signaling pathway 6.082016e-6
GO:0002718 regulation of cytokine production involved in immune response 6.259600e-6
GO:0010165 response to X-ray 7.750381e-6
GO:0002821 positive regulation of adaptive immune response 8.000437e-6
GO:0006198 cAMP catabolic process 8.329223e-6
GO:0002922 positive regulation of humoral immune response 9.634851e-6
GO:0006681 galactosylceramide metabolic process 9.981664e-6
GO:0090174 organelle membrane fusion 1.016044e-5
GO:0042987 amyloid precursor protein catabolic process 1.033839e-5
GO:0045087 innate immune response 1.072854e-5
GO:0046483 heterocycle metabolic process 1.149050e-5
GO:0072523 purine-containing compound catabolic process 1.162121e-5
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1.296172e-5
GO:0045060 negative thymic T cell selection 1.334179e-5
GO:0044270 cellular nitrogen compound catabolic process 1.385038e-5
GO:0002726 positive regulation of T cell cytokine production 1.414289e-5
GO:0072610 interleukin-12 secretion 1.439547e-5
GO:0097022 lymphocyte migration into lymph node 1.439547e-5
GO:0050892 intestinal absorption 1.565145e-5
GO:0045820 negative regulation of glycolysis 1.583914e-5
GO:0006195 purine nucleotide catabolic process 1.654354e-5
GO:0009895 negative regulation of catabolic process 1.765136e-5
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 1.874172e-5
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 1.887680e-5
GO:0032023 trypsinogen activation 1.977287e-5
GO:0009190 cyclic nucleotide biosynthetic process 1.997625e-5
GO:0097026 dendritic cell dendrite assembly 1.999057e-5
GO:0006438 valyl-tRNA aminoacylation 1.999057e-5
GO:0090022 regulation of neutrophil chemotaxis 2.018751e-5
GO:0030300 regulation of intestinal cholesterol absorption 2.140491e-5
GO:0006171 cAMP biosynthetic process 2.140491e-5
GO:0032642 regulation of chemokine production 2.148445e-5
GO:0007276 gamete generation 2.170855e-5
GO:0002281 macrophage activation involved in immune response 2.357946e-5
GO:0010758 regulation of macrophage chemotaxis 2.359975e-5
GO:0002883 regulation of hypersensitivity 2.359975e-5
GO:0071675 regulation of mononuclear cell migration 2.599230e-5
GO:2000107 negative regulation of leukocyte apoptosis 2.610176e-5
GO:0090023 positive regulation of neutrophil chemotaxis 2.665843e-5
GO:0009166 nucleotide catabolic process 2.847202e-5
GO:0009259 ribonucleotide metabolic process 2.862430e-5
GO:0009150 purine ribonucleotide metabolic process 2.902878e-5
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 2.963223e-5
GO:0071403 cellular response to high density lipoprotein particle stimulus 3.325931e-5
GO:0071448 cellular response to alkyl hydroperoxide 3.325931e-5
GO:0071315 cellular response to morphine 3.325931e-5
GO:0050904 diapedesis 3.325931e-5
GO:0071307 cellular response to vitamin K 3.325931e-5
GO:0031269 pseudopodium assembly 3.325931e-5
GO:0045123 cellular extravasation 3.451329e-5
GO:0009303 rRNA transcription 3.451329e-5
GO:0001819 positive regulation of cytokine production 3.545110e-5
GO:0032911 negative regulation of transforming growth factor beta1 production 3.632528e-5
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 3.799007e-5
GO:0010212 response to ionizing radiation 4.103041e-5
GO:0045624 positive regulation of T-helper cell differentiation 4.143083e-5
GO:0072676 lymphocyte migration 4.615677e-5
GO:0002673 regulation of acute inflammatory response 4.709082e-5
GO:0010888 negative regulation of lipid storage 4.881521e-5
GO:0045622 regulation of T-helper cell differentiation 5.340942e-5
GO:0002274 myeloid leukocyte activation 5.515216e-5
GO:0002690 positive regulation of leukocyte chemotaxis 5.665365e-5
GO:0006643 membrane lipid metabolic process 5.831334e-5
GO:0009125 nucleoside monophosphate catabolic process 6.202289e-5
GO:0001516 prostaglandin biosynthetic process 6.302070e-5
GO:0048247 lymphocyte chemotaxis 6.586544e-5
GO:0001960 negative regulation of cytokine-mediated signaling pathway 6.926178e-5
GO:0046034 ATP metabolic process 7.519460e-5
GO:0006678 glucosylceramide metabolic process 7.674040e-5
GO:0034655 nucleobase-containing compound catabolic process 7.735641e-5
GO:0031427 response to methotrexate 8.125424e-5
GO:0006360 transcription from RNA polymerase I promoter 8.520796e-5
GO:0035026 leading edge cell differentiation 8.737840e-5
GO:0002689 negative regulation of leukocyte chemotaxis 9.117290e-5
GO:0072522 purine-containing compound biosynthetic process 9.397206e-5
GO:0001774 microglial cell activation 9.727547e-5
GO:0050775 positive regulation of dendrite morphogenesis 9.853929e-5
GO:0006955 immune response 1.023886e-4
GO:0002518 lymphocyte chemotaxis across high endothelial venule 1.034832e-4
GO:2000412 positive regulation of thymocyte migration 1.034832e-4
GO:0046637 regulation of alpha-beta T cell differentiation 1.038699e-4
GO:0001959 regulation of cytokine-mediated signaling pathway 1.047849e-4
GO:0002702 positive regulation of production of molecular mediator of immune response 1.057564e-4
GO:0016485 protein processing 1.110519e-4
GO:0043383 negative T cell selection 1.116353e-4
GO:0032908 regulation of transforming growth factor beta1 production 1.217318e-4
GO:0010898 positive regulation of triglyceride catabolic process 1.217318e-4
GO:0002830 positive regulation of type 2 immune response 1.231117e-4
GO:0002649 regulation of tolerance induction to self antigen 1.269227e-4
GO:0050778 positive regulation of immune response 1.298336e-4
GO:0072659 protein localization in plasma membrane 1.298992e-4
GO:0032418 lysosome localization 1.304132e-4
GO:0010759 positive regulation of macrophage chemotaxis 1.324412e-4
GO:0060759 regulation of response to cytokine stimulus 1.334792e-4
GO:0007052 mitotic spindle organization 1.351419e-4
GO:0009205 purine ribonucleoside triphosphate metabolic process 1.356698e-4
GO:0010935 regulation of macrophage cytokine production 1.359947e-4
GO:0044241 lipid digestion 1.366245e-4
GO:0048034 heme O biosynthetic process 1.376708e-4
GO:0045226 extracellular polysaccharide biosynthetic process 1.376708e-4
GO:0006693 prostaglandin metabolic process 1.425281e-4
GO:0045061 thymic T cell selection 1.432124e-4
GO:0080135 regulation of cellular response to stress 1.438597e-4
GO:0050900 leukocyte migration 1.445057e-4
GO:0009199 ribonucleoside triphosphate metabolic process 1.455568e-4
GO:0043091 L-arginine import 1.456630e-4
GO:0045342 MHC class II biosynthetic process 1.456630e-4
GO:0060929 atrioventricular node cell fate commitment 1.456630e-4
GO:0070839 divalent metal ion export 1.456630e-4
GO:0060928 atrioventricular node cell development 1.456630e-4
GO:0035470 positive regulation of vascular wound healing 1.456630e-4
GO:0003168 cardiac Purkinje fiber cell differentiation 1.456630e-4
GO:0001923 B-1 B cell differentiation 1.456630e-4
GO:0032632 interleukin-3 production 1.456630e-4
GO:0003342 proepicardium development 1.456630e-4
GO:0006876 cellular cadmium ion homeostasis 1.456630e-4
GO:0015707 nitrite transport 1.456630e-4
GO:0009595 detection of biotic stimulus 1.471090e-4
GO:0007252 I-kappaB phosphorylation 1.506111e-4
GO:0051365 cellular response to potassium ion starvation 1.572169e-4
GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process 1.572169e-4
GO:0050921 positive regulation of chemotaxis 1.595555e-4
GO:0033233 regulation of protein sumoylation 1.612238e-4
GO:0002687 positive regulation of leukocyte migration 1.642876e-4
GO:0050920 regulation of chemotaxis 1.648901e-4
GO:0002230 positive regulation of defense response to virus by host 1.666909e-4
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 1.764845e-4
GO:0000187 activation of MAPK activity 1.883320e-4
GO:0009144 purine nucleoside triphosphate metabolic process 1.954189e-4
GO:0009141 nucleoside triphosphate metabolic process 1.975035e-4
GO:0060326 cell chemotaxis 2.061547e-4
GO:0006665 sphingolipid metabolic process 2.126907e-4
GO:0019953 sexual reproduction 2.189778e-4
GO:0045619 regulation of lymphocyte differentiation 2.233688e-4
GO:0009214 cyclic nucleotide catabolic process 2.237698e-4
GO:0006164 purine nucleotide biosynthetic process 2.256873e-4
GO:0070684 seminal clot liquefaction 2.340675e-4
GO:0061338 atrioventricular node impulse conduction delay 2.454136e-4
GO:0046638 positive regulation of alpha-beta T cell differentiation 2.467433e-4
GO:0010933 positive regulation of macrophage tolerance induction 2.540184e-4
GO:0071671 regulation of smooth muscle cell chemotaxis 2.651116e-4
GO:0031638 zymogen activation 2.700903e-4
GO:0010832 negative regulation of myotube differentiation 2.700903e-4
GO:0002697 regulation of immune effector process 2.734067e-4
GO:0010591 regulation of lamellipodium assembly 2.849209e-4
GO:0045580 regulation of T cell differentiation 2.896067e-4
GO:0009124 nucleoside monophosphate biosynthetic process 2.910420e-4
GO:0071453 cellular response to oxygen levels 2.948318e-4
GO:0042268 regulation of cytolysis 3.003790e-4
GO:0001556 oocyte maturation 3.087646e-4
GO:0002684 positive regulation of immune system process 3.191657e-4
GO:0002906 negative regulation of mature B cell apoptosis 3.247400e-4
GO:0002828 regulation of type 2 immune response 3.275472e-4
GO:0001986 negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure 3.372789e-4
GO:0002643 regulation of tolerance induction 3.372937e-4
GO:0051006 positive regulation of lipoprotein lipase activity 3.556203e-4
GO:0071447 cellular response to hydroperoxide 3.628169e-4
GO:0009167 purine ribonucleoside monophosphate metabolic process 3.698381e-4
GO:0048627 myoblast development 3.855803e-4
GO:0007250 activation of NF-kappaB-inducing kinase activity 3.906831e-4
GO:0010830 regulation of myotube differentiation 3.925320e-4
GO:0033604 negative regulation of catecholamine secretion 3.933891e-4
GO:0051604 protein maturation 4.011785e-4
GO:0016310 phosphorylation 4.087173e-4
GO:2000001 regulation of DNA damage checkpoint 4.101820e-4
GO:0031268 pseudopodium organization 4.101820e-4
GO:0048477 oogenesis 4.121274e-4
GO:0042990 regulation of transcription factor import into nucleus 4.273372e-4
GO:0002861 regulation of inflammatory response to antigenic stimulus 4.310699e-4
GO:0071635 negative regulation of transforming growth factor beta production 4.430989e-4
GO:0042982 amyloid precursor protein metabolic process 4.636629e-4
GO:0001768 establishment of T cell polarity 4.637486e-4
GO:0034695 response to prostaglandin E stimulus 4.911156e-4
GO:0016075 rRNA catabolic process 5.187029e-4
GO:0010700 negative regulation of norepinephrine secretion 5.187029e-4
GO:0002724 regulation of T cell cytokine production 5.255334e-4
GO:0002418 immune response to tumor cell 5.680016e-4
GO:0000966 RNA 5'-end processing 5.680016e-4
GO:0006636 unsaturated fatty acid biosynthetic process 5.817566e-4
GO:0002708 positive regulation of lymphocyte mediated immunity 5.845367e-4
GO:0007281 germ cell development 5.950423e-4
GO:0002309 T cell proliferation involved in immune response 5.956952e-4
GO:0045627 positive regulation of T-helper 1 cell differentiation 5.966274e-4
GO:0046634 regulation of alpha-beta T cell activation 5.987488e-4
GO:0031663 lipopolysaccharide-mediated signaling pathway 6.113664e-4
GO:0006664 glycolipid metabolic process 6.128522e-4
GO:0032615 interleukin-12 production 6.144392e-4
GO:0002407 dendritic cell chemotaxis 6.144392e-4
GO:0030203 glycosaminoglycan metabolic process 6.246399e-4
GO:0034654 nucleobase-containing compound biosynthetic process 6.502002e-4
GO:0045058 T cell selection 6.685225e-4
GO:0001920 negative regulation of receptor recycling 6.785824e-4
GO:0003222 ventricular trabecular myocardium morphogenesis 6.849851e-4
GO:0032736 positive regulation of interleukin-13 production 6.885963e-4
GO:0042994 cytoplasmic sequestering of transcription factor 6.885963e-4
GO:0010891 negative regulation of sequestering of triglyceride 6.885963e-4
GO:0006690 icosanoid metabolic process 7.250042e-4
GO:0009154 purine ribonucleotide catabolic process 7.392333e-4
GO:0006796 phosphate-containing compound metabolic process 7.403203e-4
GO:0043525 positive regulation of neuron apoptosis 7.598615e-4
GO:0010592 positive regulation of lamellipodium assembly 7.653723e-4
GO:0043249 erythrocyte maturation 7.653723e-4
GO:0009261 ribonucleotide catabolic process 7.873248e-4
GO:0032722 positive regulation of chemokine production 8.047205e-4
GO:0050854 regulation of antigen receptor-mediated signaling pathway 8.078245e-4
GO:0061337 cardiac conduction 8.278929e-4
GO:0050776 regulation of immune response 8.485507e-4
GO:0032103 positive regulation of response to external stimulus 8.522423e-4
GO:0032847 regulation of cellular pH reduction 8.529228e-4
GO:0001544 initiation of primordial ovarian follicle growth 8.756504e-4
GO:0051725 protein de-ADP-ribosylation 9.077091e-4
GO:0000073 spindle pole body separation 9.077091e-4
GO:0009165 nucleotide biosynthetic process 9.083125e-4
GO:0051930 regulation of sensory perception of pain 9.480380e-4
GO:0009161 ribonucleoside monophosphate metabolic process 9.668106e-4
GO:0042177 negative regulation of protein catabolic process 9.843442e-4
GO:0002286 T cell activation involved in immune response 9.971149e-4
GO:0071622 regulation of granulocyte chemotaxis 9.977281e-4
GO:0015914 phospholipid transport 1.007502e-3
GO:0050996 positive regulation of lipid catabolic process 1.009632e-3
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1.012839e-3
GO:0010889 regulation of sequestering of triglyceride 1.025818e-3
GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity 1.032557e-3
GO:0002070 epithelial cell maturation 1.032557e-3
GO:0042246 tissue regeneration 1.044933e-3
GO:0042345 regulation of NF-kappaB import into nucleus 1.050405e-3
GO:0002825 regulation of T-helper 1 type immune response 1.066705e-3
GO:0018130 heterocycle biosynthetic process 1.080312e-3
GO:0010430 fatty acid omega-oxidation 1.102744e-3
GO:0002357 defense response to tumor cell 1.102744e-3
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1.108306e-3
GO:0034340 response to type I interferon 1.112333e-3
GO:0009258 10-formyltetrahydrofolate catabolic process 1.112333e-3
GO:0003417 growth plate cartilage development 1.113453e-3
GO:2000401 regulation of lymphocyte migration 1.127212e-3
GO:0002764 immune response-regulating signaling pathway 1.145595e-3
GO:0071347 cellular response to interleukin-1 1.151355e-3
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 1.167987e-3
GO:0043406 positive regulation of MAP kinase activity 1.184824e-3
GO:0071731 response to nitric oxide 1.188659e-3
GO:0071504 cellular response to heparin 1.192195e-3
GO:0006756 AMP phosphorylation 1.270484e-3
GO:0090208 positive regulation of triglyceride metabolic process 1.273833e-3
GO:0055117 regulation of cardiac muscle contraction 1.301086e-3
GO:0030204 chondroitin sulfate metabolic process 1.313042e-3
GO:0032849 positive regulation of cellular pH reduction 1.322633e-3
GO:0002757 immune response-activating signal transduction 1.326614e-3
GO:0055099 response to high density lipoprotein particle stimulus 1.364435e-3
GO:0002376 immune system process 1.374493e-3
GO:0046958 nonassociative learning 1.393250e-3
GO:0015886 heme transport 1.393250e-3
GO:0000165 MAPKKK cascade 1.408398e-3
GO:0032108 negative regulation of response to nutrient levels 1.414365e-3
GO:0050795 regulation of behavior 1.434392e-3
GO:0080134 regulation of response to stress 1.444690e-3
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.446467e-3
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1.459538e-3
GO:0046037 GMP metabolic process 1.472481e-3
GO:0043519 regulation of myosin II filament organization 1.472481e-3
GO:0071503 response to heparin 1.473462e-3
GO:0042098 T cell proliferation 1.488692e-3
GO:0045059 positive thymic T cell selection 1.519741e-3
GO:0097117 guanylate kinase-associated protein clustering 1.520167e-3
GO:0097114 N-methyl-D-aspartate receptor clustering 1.520167e-3
GO:0015670 carbon dioxide transport 1.520167e-3
GO:0097112 gamma-aminobutyric acid receptor clustering 1.520167e-3
GO:0051545 negative regulation of elastin biosynthetic process 1.537863e-3
GO:0006952 defense response 1.570258e-3
GO:0050853 B cell receptor signaling pathway 1.572937e-3
GO:0042346 positive regulation of NF-kappaB import into nucleus 1.615916e-3
GO:0010896 regulation of triglyceride catabolic process 1.623295e-3
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1.644808e-3
GO:0046456 icosanoid biosynthetic process 1.649111e-3
GO:0009207 purine ribonucleoside triphosphate catabolic process 1.650614e-3
GO:0048609 multicellular organismal reproductive process 1.713133e-3
GO:0071544 diphosphoinositol polyphosphate catabolic process 1.723609e-3
GO:2000110 negative regulation of macrophage apoptosis 1.723609e-3
GO:0071673 positive regulation of smooth muscle cell chemotaxis 1.723609e-3
GO:0006433 prolyl-tRNA aminoacylation 1.723609e-3
GO:0032203 telomere formation via telomerase 1.723609e-3
GO:0060971 embryonic heart tube left/right pattern formation 1.723609e-3
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process 1.739931e-3
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.758055e-3
GO:0001961 positive regulation of cytokine-mediated signaling pathway 1.762828e-3
GO:0051929 positive regulation of calcium ion transport via voltage-gated calcium channel activity 1.805687e-3
GO:0006200 ATP catabolic process 1.835832e-3
GO:0046635 positive regulation of alpha-beta T cell activation 1.861640e-3
GO:0032902 nerve growth factor production 1.894015e-3
GO:0050766 positive regulation of phagocytosis 1.912945e-3
GO:0009143 nucleoside triphosphate catabolic process 1.919180e-3
GO:0006022 aminoglycan metabolic process 1.945818e-3
GO:0002920 regulation of humoral immune response 1.959964e-3
GO:0006468 protein phosphorylation 1.984042e-3
GO:0032754 positive regulation of interleukin-5 production 1.992879e-3
GO:0001798 positive regulation of type IIa hypersensitivity 1.995084e-3
GO:0051453 regulation of intracellular pH 2.024553e-3
GO:0009146 purine nucleoside triphosphate catabolic process 2.024669e-3
GO:0002224 toll-like receptor signaling pathway 2.070530e-3
GO:0071267 L-methionine salvage 2.106830e-3
GO:0032101 regulation of response to external stimulus 2.184491e-3
GO:0090303 positive regulation of wound healing 2.210814e-3
GO:0007283 spermatogenesis 2.268990e-3
GO:0046940 nucleoside monophosphate phosphorylation 2.277713e-3
GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway 2.277713e-3
GO:0003278 apoptosis involved in heart morphogenesis 2.277713e-3
GO:0007028 cytoplasm organization 2.310300e-3
GO:0051607 defense response to virus 2.459182e-3
GO:0070932 histone H3 deacetylation 2.549218e-3
GO:0071456 cellular response to hypoxia 2.552027e-3
GO:0048384 retinoic acid receptor signaling pathway 2.556949e-3
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 2.589780e-3
GO:0002819 regulation of adaptive immune response 2.593797e-3
GO:0006516 glycoprotein catabolic process 2.609420e-3
GO:0048537 mucosal-associated lymphoid tissue development 2.609420e-3
GO:0002478 antigen processing and presentation of exogenous peptide antigen 2.634198e-3
GO:0048610 cellular process involved in reproduction 2.661467e-3
GO:0003416 endochondral bone growth 2.783622e-3
GO:0060760 positive regulation of response to cytokine stimulus 2.816723e-3
GO:0070229 negative regulation of lymphocyte apoptosis 2.892260e-3
GO:0034661 ncRNA catabolic process 2.901787e-3
GO:0032107 regulation of response to nutrient levels 2.930066e-3
GO:0021570 rhombomere 4 development 2.943199e-3
GO:0016554 cytidine to uridine editing 2.962171e-3
GO:0051452 intracellular pH reduction 3.033566e-3
GO:0060676 ureteric bud formation 3.037373e-3
GO:0051639 actin filament network formation 3.055233e-3
GO:0045343 regulation of MHC class I biosynthetic process 3.055233e-3
GO:0032571 response to vitamin K 3.055233e-3
GO:0006937 regulation of muscle contraction 3.100924e-3
GO:0032374 regulation of cholesterol transport 3.108604e-3
GO:0006687 glycosphingolipid metabolic process 3.134127e-3
GO:0060907 positive regulation of macrophage cytokine production 3.143773e-3
GO:0007042 lysosomal lumen acidification 3.231396e-3
GO:0001816 cytokine production 3.236611e-3
GO:0002686 negative regulation of leukocyte migration 3.263620e-3
GO:0045823 positive regulation of heart contraction 3.308472e-3
GO:0045861 negative regulation of proteolysis 3.366829e-3
GO:0045625 regulation of T-helper 1 cell differentiation 3.464783e-3
GO:0018149 peptide cross-linking 3.565482e-3
GO:0010507 negative regulation of autophagy 3.577924e-3
GO:0002711 positive regulation of T cell mediated immunity 3.613945e-3
GO:0019276 UDP-N-acetylgalactosamine metabolic process 3.629817e-3
GO:0006784 heme a biosynthetic process 3.629817e-3
GO:0007127 meiosis I 3.639724e-3
GO:0007249 I-kappaB kinase/NF-kappaB cascade 3.683366e-3
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 3.730158e-3
GO:0008582 regulation of synaptic growth at neuromuscular junction 3.730158e-3
GO:0007144 female meiosis I 3.730158e-3
GO:0032880 regulation of protein localization 3.732498e-3
GO:0010820 positive regulation of T cell chemotaxis 3.765645e-3
GO:0006477 protein sulfation 3.776672e-3
GO:0060754 positive regulation of mast cell chemotaxis 3.837112e-3
GO:0016045 detection of bacterium 3.837112e-3
GO:0002051 osteoblast fate commitment 3.837112e-3
GO:0051085 chaperone mediated protein folding requiring cofactor 3.845943e-3
GO:0007530 sex determination 3.861920e-3
GO:0001974 blood vessel remodeling 4.011628e-3
GO:2000406 positive regulation of T cell migration 4.038784e-3
GO:0050663 cytokine secretion 4.089915e-3
GO:0048599 oocyte development 4.091829e-3
GO:0051209 release of sequestered calcium ion into cytosol 4.133313e-3
GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway 4.133698e-3
GO:0072657 protein localization in membrane 4.149339e-3
GO:0051220 cytoplasmic sequestering of protein 4.150320e-3
GO:0035196 production of miRNAs involved in gene silencing by miRNA 4.150320e-3
GO:0046086 adenosine biosynthetic process 4.238097e-3
GO:0006196 AMP catabolic process 4.238097e-3
GO:0046640 regulation of alpha-beta T cell proliferation 4.251602e-3
GO:0060010 Sertoli cell fate commitment 4.277898e-3
GO:0051127 positive regulation of actin nucleation 4.277898e-3
GO:0050994 regulation of lipid catabolic process 4.390917e-3
GO:0043410 positive regulation of MAPKKK cascade 4.406716e-3
GO:0007588 excretion 4.455286e-3
GO:0008052 sensory organ boundary specification 4.493012e-3
GO:0035522 monoubiquitinated histone H2A deubiquitination 4.493012e-3
GO:0007402 ganglion mother cell fate determination 4.493012e-3
GO:0042992 negative regulation of transcription factor import into nucleus 4.510537e-3
GO:0048535 lymph node development 4.523507e-3
GO:0010559 regulation of glycoprotein biosynthetic process 4.628592e-3
GO:0007035 vacuolar acidification 4.648301e-3
GO:2001020 regulation of response to DNA damage stimulus 4.737932e-3
GO:0002700 regulation of production of molecular mediator of immune response 4.824928e-3
GO:0031054 pre-miRNA processing 4.845600e-3
GO:0051891 positive regulation of cardioblast differentiation 4.939413e-3
GO:0030252 growth hormone secretion 5.003665e-3
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 5.015592e-3
GO:0070201 regulation of establishment of protein localization 5.029634e-3
GO:0046328 regulation of JNK cascade 5.046605e-3
GO:0018298 protein-chromophore linkage 5.069692e-3
GO:0033194 response to hydroperoxide 5.251889e-3
GO:0032102 negative regulation of response to external stimulus 5.374988e-3
GO:0006029 proteoglycan metabolic process 5.439302e-3
GO:0051154 negative regulation of striated muscle cell differentiation 5.562466e-3
GO:0007184 SMAD protein import into nucleus 5.579881e-3
GO:0042093 T-helper cell differentiation 5.650036e-3
GO:0043331 response to dsRNA 5.697698e-3
GO:0051615 histamine uptake 5.706893e-3
GO:0034112 positive regulation of homotypic cell-cell adhesion 5.706893e-3
GO:0006424 glutamyl-tRNA aminoacylation 5.706893e-3
GO:0032608 interferon-beta production 5.706893e-3
GO:0007004 telomere maintenance via telomerase 5.706893e-3
GO:0060586 multicellular organismal iron ion homeostasis 5.814041e-3
GO:0030046 parallel actin filament bundle assembly 5.814041e-3
GO:0009994 oocyte differentiation 5.826158e-3
GO:0043368 positive T cell selection 5.863770e-3
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 5.866519e-3
GO:0045638 negative regulation of myeloid cell differentiation 5.980442e-3
GO:0045851 pH reduction 6.025800e-3
GO:0002253 activation of immune response 6.074595e-3
GO:0007292 female gamete generation 6.121238e-3
GO:0050688 regulation of defense response to virus 6.133614e-3
GO:0032874 positive regulation of stress-activated MAPK cascade 6.135608e-3
GO:0043278 response to morphine 6.196154e-3
GO:0006790 sulfur compound metabolic process 6.244785e-3
GO:0051045 negative regulation of membrane protein ectodomain proteolysis 6.284533e-3
GO:0019752 carboxylic acid metabolic process 6.347626e-3
GO:0070257 positive regulation of mucus secretion 6.364017e-3
GO:0003085 negative regulation of systemic arterial blood pressure 6.384535e-3
GO:0070302 regulation of stress-activated protein kinase signaling cascade 6.556811e-3
GO:0007183 SMAD protein complex assembly 6.584061e-3
GO:0015780 nucleotide-sugar transport 6.750054e-3
GO:0006119 oxidative phosphorylation 6.836022e-3
GO:0034113 heterotypic cell-cell adhesion 6.848206e-3
GO:0043403 skeletal muscle tissue regeneration 6.890950e-3
GO:0006189 'de novo' IMP biosynthetic process 6.914703e-3
GO:0008156 negative regulation of DNA replication 6.941731e-3
GO:0042993 positive regulation of transcription factor import into nucleus 6.957768e-3
GO:0002903 negative regulation of B cell apoptosis 7.113698e-3
GO:0044255 cellular lipid metabolic process 7.128584e-3
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 7.157959e-3
GO:0070555 response to interleukin-1 7.161159e-3
GO:0042180 cellular ketone metabolic process 7.267418e-3
GO:0016080 synaptic vesicle targeting 7.271810e-3
GO:0030641 regulation of cellular pH 7.409175e-3
GO:0033235 positive regulation of protein sumoylation 7.422012e-3
GO:0005513 detection of calcium ion 7.422012e-3
GO:0001970 positive regulation of activation of membrane attack complex 7.422012e-3