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Novel motif:169

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name:motif169_GCCTGGCC

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0034505 tooth mineralization 2.044831e-20
GO:0060346 bone trabecula formation 1.235340e-18
GO:0032964 collagen biosynthetic process 1.884869e-18
GO:0006544 glycine metabolic process 5.133393e-16
GO:0060351 cartilage development involved in endochondral bone morphogenesis 9.304262e-16
GO:0060343 trabecula formation 3.127273e-15
GO:0061383 trabecula morphogenesis 1.080705e-14
GO:0070208 protein heterotrimerization 3.527488e-14
GO:0001957 intramembranous ossification 3.565337e-14
GO:0045112 integrin biosynthetic process 1.026234e-13
GO:0032863 activation of Rac GTPase activity 2.285702e-12
GO:0010624 regulation of Schwann cell proliferation 3.851880e-12
GO:0045217 cell-cell junction maintenance 1.099334e-11
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 3.004794e-11
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 4.405783e-11
GO:0043503 skeletal muscle fiber adaptation 6.586308e-11
GO:0042506 tyrosine phosphorylation of Stat5 protein 7.121808e-11
GO:0046655 folic acid metabolic process 1.776576e-10
GO:0043089 positive regulation of Cdc42 GTPase activity 1.908502e-10
GO:0032383 regulation of intracellular cholesterol transport 2.185450e-10
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 2.722965e-10
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 2.982277e-10
GO:0032793 positive regulation of CREB transcription factor activity 4.956680e-10
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 8.539334e-10
GO:0035814 negative regulation of renal sodium excretion 8.649524e-10
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 9.255152e-10
GO:0071956 cellular component maintenance at cellular level 1.066993e-9
GO:0032012 regulation of ARF protein signal transduction 1.072194e-9
GO:0006545 glycine biosynthetic process 1.384080e-9
GO:0031442 positive regulation of mRNA 3'-end processing 1.644403e-9
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 3.181368e-9
GO:0043088 regulation of Cdc42 GTPase activity 4.237337e-9
GO:0035313 wound healing, spreading of epidermal cells 4.760228e-9
GO:0051764 actin crosslink formation 5.043327e-9
GO:0016056 rhodopsin mediated signaling pathway 5.863975e-9
GO:2000467 positive regulation of glycogen (starch) synthase activity 6.139837e-9
GO:0016458 gene silencing 6.193088e-9
GO:0007386 compartment pattern specification 6.353179e-9
GO:0070483 detection of hypoxia 8.744670e-9
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 9.077464e-9
GO:0060482 lobar bronchus development 9.479160e-9
GO:0035470 positive regulation of vascular wound healing 1.373786e-8
GO:0035357 peroxisome proliferator activated receptor signaling pathway 1.415152e-8
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 1.423010e-8
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 1.423010e-8
GO:0071072 negative regulation of phospholipid biosynthetic process 1.568118e-8
GO:0032425 positive regulation of mismatch repair 2.124565e-8
GO:0060708 spongiotrophoblast differentiation 2.184494e-8
GO:0046628 positive regulation of insulin receptor signaling pathway 2.539179e-8
GO:0007635 chemosensory behavior 2.627199e-8
GO:0014028 notochord formation 3.024988e-8
GO:0046626 regulation of insulin receptor signaling pathway 3.468117e-8
GO:0071071 regulation of phospholipid biosynthetic process 4.163823e-8
GO:0051291 protein heterooligomerization 4.711150e-8
GO:0010625 positive regulation of Schwann cell proliferation 4.753289e-8
GO:0042074 cell migration involved in gastrulation 6.583476e-8
GO:0042503 tyrosine phosphorylation of Stat3 protein 7.848037e-8
GO:0002149 hypochlorous acid biosynthetic process 8.004846e-8
GO:0002528 regulation of vascular permeability involved in acute inflammatory response 9.408224e-8
GO:2000465 regulation of glycogen (starch) synthase activity 9.701618e-8
GO:0003009 skeletal muscle contraction 9.926720e-8
GO:0032423 regulation of mismatch repair 1.046833e-7
GO:0033326 cerebrospinal fluid secretion 1.338379e-7
GO:0051488 activation of anaphase-promoting complex activity 1.384404e-7
GO:0002019 regulation of renal output by angiotensin 1.708372e-7
GO:0002679 respiratory burst involved in defense response 1.729761e-7
GO:0022009 central nervous system vasculogenesis 2.105411e-7
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 2.204287e-7
GO:0044319 wound healing, spreading of cells 2.446193e-7
GO:0072060 outer medullary collecting duct development 2.495661e-7
GO:0072061 inner medullary collecting duct development 2.495661e-7
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 2.495661e-7
GO:0033209 tumor necrosis factor-mediated signaling pathway 2.898590e-7
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 3.356069e-7
GO:0010718 positive regulation of epithelial to mesenchymal transition 3.740058e-7
GO:0060534 trachea cartilage development 3.757393e-7
GO:0021526 medial motor column neuron differentiation 3.870312e-7
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 3.870312e-7
GO:0006012 galactose metabolic process 4.025184e-7
GO:0032312 regulation of ARF GTPase activity 4.594910e-7
GO:0060419 heart growth 4.800913e-7
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 5.756424e-7
GO:0009069 serine family amino acid metabolic process 5.862678e-7
GO:0008078 mesodermal cell migration 6.487725e-7
GO:0048320 axial mesoderm formation 6.747422e-7
GO:0051645 Golgi localization 6.771282e-7
GO:0043487 regulation of RNA stability 7.713605e-7
GO:0010511 regulation of phosphatidylinositol biosynthetic process 8.181526e-7
GO:0018293 protein-FAD linkage 8.309421e-7
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 8.309421e-7
GO:0014807 regulation of somitogenesis 8.406556e-7
GO:0006337 nucleosome disassembly 8.764342e-7
GO:0051534 negative regulation of NFAT protein import into nucleus 9.057967e-7
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 9.090792e-7
GO:0050685 positive regulation of mRNA processing 1.092042e-6
GO:0055017 cardiac muscle tissue growth 1.094426e-6
GO:0032862 activation of Rho GTPase activity 1.280679e-6
GO:0006261 DNA-dependent DNA replication 1.316081e-6
GO:0031440 regulation of mRNA 3'-end processing 1.317329e-6
GO:0045415 negative regulation of interleukin-8 biosynthetic process 1.326688e-6
GO:0060251 regulation of glial cell proliferation 1.458516e-6
GO:0060035 notochord cell development 1.529582e-6
GO:0043488 regulation of mRNA stability 1.586750e-6
GO:0007506 gonadal mesoderm development 1.967478e-6
GO:0042274 ribosomal small subunit biogenesis 1.991284e-6
GO:0055026 negative regulation of cardiac muscle tissue development 2.049137e-6
GO:0035572 N-terminal peptidyl-serine dimethylation 2.277363e-6
GO:0035573 N-terminal peptidyl-serine trimethylation 2.277363e-6
GO:0018012 N-terminal peptidyl-alanine trimethylation 2.277363e-6
GO:0018016 N-terminal peptidyl-proline dimethylation 2.277363e-6
GO:0019388 galactose catabolic process 2.406462e-6
GO:0006349 regulation of gene expression by genetic imprinting 2.435476e-6
GO:0060253 negative regulation of glial cell proliferation 2.471088e-6
GO:0033002 muscle cell proliferation 2.471088e-6
GO:0071300 cellular response to retinoic acid 2.804226e-6
GO:0060535 trachea cartilage morphogenesis 3.069188e-6
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 3.208402e-6
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 3.375479e-6
GO:0071299 cellular response to vitamin A 3.443678e-6
GO:0006264 mitochondrial DNA replication 3.897910e-6
GO:0006984 ER-nucleus signaling pathway 3.975667e-6
GO:0043314 negative regulation of neutrophil degranulation 4.062631e-6
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 4.115950e-6
GO:0006342 chromatin silencing 4.277426e-6
GO:0005984 disaccharide metabolic process 4.730664e-6
GO:0000028 ribosomal small subunit assembly 4.784327e-6
GO:0002432 granuloma formation 5.066012e-6
GO:2000249 regulation of actin cytoskeleton reorganization 5.509958e-6
GO:0071549 cellular response to dexamethasone stimulus 5.509958e-6
GO:0001880 Mullerian duct regression 5.518682e-6
GO:0030037 actin filament reorganization involved in cell cycle 5.959157e-6
GO:0032506 cytokinetic process 6.277670e-6
GO:0010626 negative regulation of Schwann cell proliferation 7.040573e-6
GO:0030952 establishment or maintenance of cytoskeleton polarity 7.142924e-6
GO:0031365 N-terminal protein amino acid modification 7.547575e-6
GO:0060160 negative regulation of dopamine receptor signaling pathway 7.610004e-6
GO:0043628 ncRNA 3'-end processing 7.924530e-6
GO:0060707 trophoblast giant cell differentiation 8.489657e-6
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 8.735291e-6
GO:0006646 phosphatidylethanolamine biosynthetic process 8.857959e-6
GO:0015879 carnitine transport 8.962957e-6
GO:0051321 meiotic cell cycle 9.551441e-6
GO:0032972 regulation of muscle filament sliding speed 1.000059e-5
GO:2000143 negative regulation of transcription initiation, DNA-dependent 1.009527e-5
GO:0042866 pyruvate biosynthetic process 1.027897e-5
GO:0071316 cellular response to nicotine 1.031848e-5
GO:0001560 regulation of cell growth by extracellular stimulus 1.045464e-5
GO:0090031 positive regulation of steroid hormone biosynthetic process 1.133603e-5
GO:0006289 nucleotide-excision repair 1.166752e-5
GO:0010918 positive regulation of mitochondrial membrane potential 1.241067e-5
GO:0044342 type B pancreatic cell proliferation 1.241067e-5
GO:0007141 male meiosis I 1.245805e-5
GO:0032049 cardiolipin biosynthetic process 1.401681e-5
GO:0007051 spindle organization 1.549288e-5
GO:0018208 peptidyl-proline modification 1.784877e-5
GO:0060456 positive regulation of digestive system process 1.870516e-5
GO:0048144 fibroblast proliferation 1.885612e-5
GO:0031047 gene silencing by RNA 1.895021e-5
GO:0060712 spongiotrophoblast layer development 1.910501e-5
GO:0006546 glycine catabolic process 1.946528e-5
GO:0034214 protein hexamerization 2.098563e-5
GO:0060038 cardiac muscle cell proliferation 2.345415e-5
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 2.353166e-5
GO:0002438 acute inflammatory response to antigenic stimulus 2.427031e-5
GO:0010893 positive regulation of steroid biosynthetic process 2.532396e-5
GO:0032042 mitochondrial DNA metabolic process 2.703776e-5
GO:0000305 response to oxygen radical 2.717279e-5
GO:2000210 positive regulation of anoikis 2.840918e-5
GO:0072109 glomerular mesangium development 2.910455e-5
GO:0048242 epinephrine secretion 2.944784e-5
GO:0046724 oxalic acid secretion 2.944784e-5
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 2.944784e-5
GO:0045835 negative regulation of meiosis 2.991543e-5
GO:0048702 embryonic neurocranium morphogenesis 3.232237e-5
GO:0015891 siderophore transport 3.389446e-5
GO:0045814 negative regulation of gene expression, epigenetic 3.765748e-5
GO:0000413 protein peptidyl-prolyl isomerization 3.817621e-5
GO:0071514 genetic imprinting 3.838427e-5
GO:0003084 positive regulation of systemic arterial blood pressure 3.903394e-5
GO:0000084 S phase of mitotic cell cycle 3.997182e-5
GO:0045955 negative regulation of calcium ion-dependent exocytosis 4.120462e-5
GO:0007126 meiosis 4.199443e-5
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 4.217520e-5
GO:0006669 sphinganine-1-phosphate biosynthetic process 4.217520e-5
GO:0009386 translational attenuation 4.217520e-5
GO:0071816 tail-anchored membrane protein insertion into ER membrane 4.275500e-5
GO:0048255 mRNA stabilization 4.567391e-5
GO:0032007 negative regulation of TOR signaling cascade 4.630794e-5
GO:0030421 defecation 4.695916e-5
GO:0071585 detoxification of cadmium ion 4.734351e-5
GO:0032094 response to food 5.133105e-5
GO:0031064 negative regulation of histone deacetylation 5.158530e-5
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 5.172499e-5
GO:0009071 serine family amino acid catabolic process 5.423953e-5
GO:0007283 spermatogenesis 5.842624e-5
GO:0007509 mesoderm migration involved in gastrulation 5.869584e-5
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 5.926386e-5
GO:0051898 negative regulation of protein kinase B signaling cascade 6.321379e-5
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 6.364131e-5
GO:0070574 cadmium ion transmembrane transport 6.403408e-5
GO:0000389 nuclear mRNA 3'-splice site recognition 6.416923e-5
GO:0035307 positive regulation of protein dephosphorylation 6.875101e-5
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 7.016065e-5
GO:0048243 norepinephrine secretion 7.016065e-5
GO:0060706 cell differentiation involved in embryonic placenta development 7.243754e-5
GO:0045940 positive regulation of steroid metabolic process 7.270982e-5
GO:0031017 exocrine pancreas development 7.419231e-5
GO:0032984 macromolecular complex disassembly 7.579103e-5
GO:0035419 activation of MAPK activity involved in innate immune response 7.844248e-5
GO:0060381 positive regulation of single-stranded telomeric DNA binding 8.535648e-5
GO:0006423 cysteinyl-tRNA aminoacylation 8.535648e-5
GO:0031468 nuclear envelope reassembly 8.661023e-5
GO:0001546 preantral ovarian follicle growth 8.661023e-5
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 8.815887e-5
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 9.067560e-5
GO:0035306 positive regulation of dephosphorylation 9.638314e-5
GO:0010874 regulation of cholesterol efflux 9.857200e-5
GO:0015884 folic acid transport 9.997622e-5
GO:0051693 actin filament capping 1.009759e-4
GO:0007341 penetration of zona pellucida 1.088566e-4
GO:0007212 dopamine receptor signaling pathway 1.093790e-4
GO:0022617 extracellular matrix disassembly 1.094308e-4
GO:0043585 nose morphogenesis 1.127606e-4
GO:0050902 leukocyte adhesive activation 1.146436e-4
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 1.146436e-4
GO:0035105 sterol regulatory element binding protein import into nucleus 1.146436e-4
GO:0010875 positive regulation of cholesterol efflux 1.148625e-4
GO:0032526 response to retinoic acid 1.157900e-4
GO:0034976 response to endoplasmic reticulum stress 1.241442e-4
GO:0045820 negative regulation of glycolysis 1.270252e-4
GO:0006438 valyl-tRNA aminoacylation 1.310071e-4
GO:0003108 negative regulation of the force of heart contraction by chemical signal 1.382009e-4
GO:0048570 notochord morphogenesis 1.387578e-4
GO:0010985 negative regulation of lipoprotein particle clearance 1.387578e-4
GO:0022038 corpus callosum development 1.450374e-4
GO:0032376 positive regulation of cholesterol transport 1.482604e-4
GO:0007109 cytokinesis, completion of separation 1.550814e-4
GO:0015804 neutral amino acid transport 1.566610e-4
GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis 1.620925e-4
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 1.629047e-4
GO:0051013 microtubule severing 1.629047e-4
GO:0051586 positive regulation of dopamine uptake 1.638172e-4
GO:0060338 regulation of type I interferon-mediated signaling pathway 1.643920e-4
GO:2000573 positive regulation of DNA biosynthetic process 1.664698e-4
GO:0051532 regulation of NFAT protein import into nucleus 1.666558e-4
GO:0006356 regulation of transcription from RNA polymerase I promoter 1.666558e-4
GO:0043313 regulation of neutrophil degranulation 1.715519e-4
GO:0051220 cytoplasmic sequestering of protein 1.715630e-4
GO:0031848 protection from non-homologous end joining at telomere 1.719766e-4
GO:0043181 vacuolar sequestering 1.778602e-4
GO:0060764 cell-cell signaling involved in mammary gland development 1.778602e-4
GO:0005985 sucrose metabolic process 1.778602e-4
GO:0000023 maltose metabolic process 1.778602e-4
GO:0030327 prenylated protein catabolic process 1.785874e-4
GO:0045090 retroviral genome replication 1.785874e-4
GO:0030309 poly-N-acetyllactosamine metabolic process 1.785874e-4
GO:0000303 response to superoxide 1.811743e-4
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 1.831706e-4
GO:0033505 floor plate morphogenesis 1.846446e-4
GO:0051414 response to cortisol stimulus 1.892923e-4
GO:0035967 cellular response to topologically incorrect protein 1.908598e-4
GO:0090305 nucleic acid phosphodiester bond hydrolysis 1.990220e-4
GO:0032796 uropod organization 2.057759e-4
GO:0070307 lens fiber cell development 2.064941e-4
GO:0032515 negative regulation of phosphoprotein phosphatase activity 2.065854e-4
GO:0009451 RNA modification 2.078720e-4
GO:0060236 regulation of mitotic spindle organization 2.115103e-4
GO:0007021 tubulin complex assembly 2.120730e-4
GO:0006353 transcription termination, DNA-dependent 2.162255e-4
GO:0031125 rRNA 3'-end processing 2.182042e-4
GO:0040030 regulation of molecular function, epigenetic 2.182042e-4
GO:0002036 regulation of L-glutamate transport 2.242842e-4
GO:0000185 activation of MAPKKK activity 2.321810e-4
GO:0060997 dendritic spine morphogenesis 2.403175e-4
GO:0006760 folic acid-containing compound metabolic process 2.431791e-4
GO:0097152 mesenchymal cell apoptosis 2.434657e-4
GO:2001037 positive regulation of tongue muscle cell differentiation 2.434657e-4
GO:0060982 coronary artery morphogenesis 2.434657e-4
GO:0006281 DNA repair 2.436452e-4
GO:0019048 virus-host interaction 2.483373e-4
GO:0060014 granulosa cell differentiation 2.557366e-4
GO:0043096 purine base salvage 2.557366e-4
GO:0002069 columnar/cuboidal epithelial cell maturation 2.562132e-4
GO:0046778 modification by virus of host mRNA processing 2.611409e-4
GO:0030046 parallel actin filament bundle assembly 2.611409e-4
GO:0009440 cyanate catabolic process 2.611409e-4
GO:0009650 UV protection 2.640581e-4
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 2.775641e-4
GO:0070194 synaptonemal complex disassembly 2.775641e-4
GO:0006335 DNA replication-dependent nucleosome assembly 2.792765e-4
GO:0010994 free ubiquitin chain polymerization 2.869424e-4
GO:0006420 arginyl-tRNA aminoacylation 2.869424e-4
GO:0001885 endothelial cell development 2.893318e-4
GO:0000212 meiotic spindle organization 2.904280e-4
GO:0045218 zonula adherens maintenance 3.001685e-4
GO:0006772 thiamine metabolic process 3.060105e-4
GO:0019264 glycine biosynthetic process from serine 3.062170e-4
GO:0060350 endochondral bone morphogenesis 3.205785e-4
GO:0090239 regulation of histone H4 acetylation 3.438106e-4
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 3.451063e-4
GO:0097107 postsynaptic density assembly 3.451063e-4
GO:0002077 acrosome matrix dispersal 3.652463e-4
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 3.696234e-4
GO:0072205 metanephric collecting duct development 3.720497e-4
GO:0090205 positive regulation of cholesterol metabolic process 3.728007e-4
GO:0090241 negative regulation of histone H4 acetylation 3.761492e-4
GO:0051781 positive regulation of cell division 3.876916e-4
GO:0071280 cellular response to copper ion 3.911706e-4
GO:0006419 alanyl-tRNA aminoacylation 3.911706e-4
GO:0021508 floor plate formation 3.911706e-4
GO:0046939 nucleotide phosphorylation 3.969335e-4
GO:0001842 neural fold formation 4.053825e-4
GO:0006268 DNA unwinding involved in replication 4.234592e-4
GO:0010889 regulation of sequestering of triglyceride 4.251824e-4
GO:0045838 positive regulation of membrane potential 4.264120e-4
GO:0044259 multicellular organismal macromolecule metabolic process 4.314306e-4
GO:0071732 cellular response to nitric oxide 4.331943e-4
GO:0009070 serine family amino acid biosynthetic process 4.332607e-4
GO:0021523 somatic motor neuron differentiation 4.391612e-4
GO:0006360 transcription from RNA polymerase I promoter 4.421061e-4
GO:0007196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway 4.448804e-4
GO:0014909 smooth muscle cell migration 4.462874e-4
GO:0048194 Golgi vesicle budding 4.533429e-4
GO:0032864 activation of Cdc42 GTPase activity 4.650910e-4
GO:0030513 positive regulation of BMP signaling pathway 4.675363e-4
GO:0002074 extraocular skeletal muscle development 4.767124e-4
GO:0046878 positive regulation of saliva secretion 4.767124e-4
GO:0010225 response to UV-C 4.835939e-4
GO:0060290 transdifferentiation 4.861686e-4
GO:0002268 follicular dendritic cell differentiation 4.927281e-4
GO:0070206 protein trimerization 4.966108e-4
GO:0070947 neutrophil mediated killing of fungus 4.993373e-4
GO:0031330 negative regulation of cellular catabolic process 5.027163e-4
GO:0007140 male meiosis 5.089273e-4
GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity 5.239306e-4
GO:0048319 axial mesoderm morphogenesis 5.414353e-4
GO:0045651 positive regulation of macrophage differentiation 5.444103e-4
GO:0009133 nucleoside diphosphate biosynthetic process 5.475731e-4
GO:0071731 response to nitric oxide 5.484601e-4
GO:0001881 receptor recycling 5.555944e-4
GO:0019430 removal of superoxide radicals 5.557454e-4
GO:0048241 epinephrine transport 5.645346e-4
GO:0042508 tyrosine phosphorylation of Stat1 protein 5.673833e-4
GO:0032415 regulation of sodium:hydrogen antiporter activity 5.743983e-4
GO:0032926 negative regulation of activin receptor signaling pathway 5.823702e-4
GO:0032205 negative regulation of telomere maintenance 5.873925e-4
GO:0046533 negative regulation of photoreceptor cell differentiation 5.997728e-4
GO:0043932 ossification involved in bone remodeling 6.070178e-4
GO:0072668 tubulin complex biogenesis 6.236990e-4
GO:0034623 cellular macromolecular complex disassembly 6.350666e-4
GO:0072333 signal transduction by p53 class mediator resulting in induction of anoikis 6.470774e-4
GO:0015695 organic cation transport 6.528042e-4
GO:0006308 DNA catabolic process 6.578339e-4
GO:0046607 positive regulation of centrosome cycle 6.642656e-4
GO:0045472 response to ether 6.642656e-4
GO:0002642 positive regulation of immunoglobulin biosynthetic process 6.642656e-4
GO:0035499 carnosine biosynthetic process 6.642656e-4
GO:0010717 regulation of epithelial to mesenchymal transition 6.662087e-4
GO:0048199 vesicle targeting, to, from or within Golgi 6.764399e-4
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 6.779560e-4
GO:0031129 inductive cell-cell signaling 6.837252e-4
GO:0051955 regulation of amino acid transport 6.921616e-4
GO:0030835 negative regulation of actin filament depolymerization 6.963289e-4
GO:0045542 positive regulation of cholesterol biosynthetic process 7.199259e-4
GO:0046755 non-lytic virus budding 7.253683e-4
GO:0090232 positive regulation of spindle checkpoint 7.358050e-4
GO:0043094 cellular metabolic compound salvage 7.385647e-4
GO:0046604 positive regulation of mitotic centrosome separation 7.500503e-4
GO:0060377 negative regulation of mast cell differentiation 7.500503e-4
GO:0045403 negative regulation of interleukin-4 biosynthetic process 7.500503e-4
GO:0070625 zymogen granule exocytosis 7.500503e-4
GO:0000379 tRNA-type intron splice site recognition and cleavage 7.500503e-4
GO:0002295 T-helper cell lineage commitment 7.500503e-4
GO:0003192 mitral valve formation 7.500503e-4
GO:0003195 tricuspid valve formation 7.500503e-4
GO:0042723 thiamine-containing compound metabolic process 7.514985e-4
GO:0015816 glycine transport 7.514985e-4
GO:0042760 very long-chain fatty acid catabolic process 7.561447e-4
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 7.705176e-4
GO:0060349 bone morphogenesis 7.772503e-4
GO:0043491 protein kinase B signaling cascade 7.772696e-4
GO:0006369 termination of RNA polymerase II transcription 8.083711e-4
GO:0010711 negative regulation of collagen catabolic process 8.272870e-4
GO:0060313 negative regulation of blood vessel remodeling 8.272870e-4
GO:0060311 negative regulation of elastin catabolic process 8.272870e-4
GO:0010703 negative regulation of histolysis 8.272870e-4
GO:0000917 barrier septum formation 8.272870e-4
GO:0008065 establishment of blood-nerve barrier 8.272870e-4
GO:0033599 regulation of mammary gland epithelial cell proliferation 8.338538e-4
GO:0000920 cytokinetic cell separation 8.357028e-4
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 8.357028e-4
GO:0018023 peptidyl-lysine trimethylation 8.564082e-4
GO:0010987 negative regulation of high-density lipoprotein particle clearance 8.628152e-4
GO:0010897 negative regulation of triglyceride catabolic process 8.628152e-4
GO:0072110 glomerular mesangial cell proliferation 8.695299e-4
GO:0007063 regulation of sister chromatid cohesion 8.697793e-4
GO:0007127 meiosis I 8.905029e-4
GO:0019101 female somatic sex determination 8.908267e-4
GO:0042703 menstruation 8.908267e-4
GO:0035304 regulation of protein dephosphorylation 9.301070e-4
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion 9.325608e-4
GO:0032792 negative regulation of CREB transcription factor activity 9.426045e-4
GO:0051016 barbed-end actin filament capping 9.662603e-4
GO:0060391 positive regulation of SMAD protein import into nucleus 9.808199e-4
GO:0010591 regulation of lamellipodium assembly 9.893401e-4
GO:0006400 tRNA modification 9.897815e-4
GO:0002002 regulation of angiotensin levels in blood 1.001498e-3
GO:0030968 endoplasmic reticulum unfolded protein response 1.005993e-3
GO:0046069 cGMP catabolic process 1.011519e-3
GO:0046102 inosine metabolic process 1.030189e-3
GO:0060179 male mating behavior 1.039024e-3
GO:0097039 protein linear polyubiquitination 1.043430e-3
GO:0046730 induction of host immune response by virus 1.075004e-3
GO:0042069 regulation of catecholamine metabolic process 1.092122e-3
GO:0010984 regulation of lipoprotein particle clearance 1.093621e-3
GO:0050881 musculoskeletal movement 1.100059e-3
GO:0048205 COPI coating of Golgi vesicle 1.120270e-3
GO:0010745 negative regulation of macrophage derived foam cell differentiation 1.147556e-3
GO:0060547 negative regulation of necrotic cell death 1.149478e-3
GO:2000369 regulation of clathrin-mediated endocytosis 1.154660e-3
GO:2001054 negative regulation of mesenchymal cell apoptosis 1.195380e-3
GO:0006998 nuclear envelope organization 1.204860e-3
GO:0001909 leukocyte mediated cytotoxicity 1.209576e-3
GO:0090281 negative regulation of calcium ion import 1.272860e-3
GO:0071584 negative regulation of zinc ion import 1.272860e-3
GO:0030311 poly-N-acetyllactosamine biosynthetic process 1.272860e-3
GO:0048318 axial mesoderm development 1.318844e-3
GO:0007614 short-term memory 1.324680e-3
GO:0043097 pyrimidine nucleoside salvage 1.329972e-3
GO:0045541 negative regulation of cholesterol biosynthetic process 1.348917e-3
GO:2000077 negative regulation of type B pancreatic cell development 1.348917e-3
GO:0018277 protein deamination 1.348917e-3
GO:0051004 regulation of lipoprotein lipase activity 1.378306e-3
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 1.401493e-3
GO:0001835 blastocyst hatching 1.401493e-3
GO:0035308 negative regulation of protein dephosphorylation 1.413802e-3
GO:0072134 nephrogenic mesenchyme morphogenesis 1.417281e-3
GO:0070634 transepithelial ammonium transport 1.430414e-3
GO:0060669 embryonic placenta morphogenesis 1.439862e-3
GO:0019402 galactitol metabolic process 1.479434e-3
GO:0008216 spermidine metabolic process 1.479434e-3
GO:0021707 cerebellar granule cell differentiation 1.504877e-3
GO:0085018 maintenance of symbiont-containing vacuole via substance secreted by host 1.510738e-3
GO:0035378 carbon dioxide transmembrane transport 1.510738e-3
GO:0035377 transepithelial water transport 1.510738e-3
GO:0008295 spermidine biosynthetic process 1.510738e-3
GO:0030950 establishment or maintenance of actin cytoskeleton polarity 1.510738e-3
GO:0032782 bile acid secretion 1.510738e-3
GO:0015696 ammonium transport 1.515781e-3
GO:0060375 regulation of mast cell differentiation 1.538555e-3
GO:0097037 heme export 1.540255e-3
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 1.540255e-3
GO:0018916 nitrobenzene metabolic process 1.540255e-3
GO:0006696 ergosterol biosynthetic process 1.540255e-3
GO:0034635 glutathione transport 1.552143e-3
GO:0001830 trophectodermal cell fate commitment 1.552143e-3
GO:0006361 transcription initiation from RNA polymerase I promoter 1.562693e-3
GO:0034447 very-low-density lipoprotein particle clearance 1.580550e-3
GO:0033239 negative regulation of cellular amine metabolic process 1.580671e-3
GO:0003416 endochondral bone growth 1.596134e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1.620153e-3
GO:0006560 proline metabolic process 1.663178e-3
GO:0030187 melatonin biosynthetic process 1.673548e-3
GO:0035767 endothelial cell chemotaxis 1.682372e-3
GO:0090311 regulation of protein deacetylation 1.685992e-3
GO:0060996 dendritic spine development 1.711817e-3
GO:0007260 tyrosine phosphorylation of STAT protein 1.715560e-3
GO:0070309 lens fiber cell morphogenesis 1.716135e-3
GO:0014037 Schwann cell differentiation 1.717905e-3
GO:0051320 S phase 1.750685e-3
GO:0006290 pyrimidine dimer repair 1.773021e-3
GO:0002067 glandular epithelial cell differentiation 1.799717e-3
GO:0010891 negative regulation of sequestering of triglyceride 1.806547e-3
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 1.859275e-3
GO:0046813 virion attachment, binding of host cell surface receptor 1.868505e-3
GO:0046103 inosine biosynthetic process 1.928856e-3
GO:0045064 T-helper 2 cell differentiation 1.928856e-3
GO:0002315 marginal zone B cell differentiation 1.928856e-3
GO:0006154 adenosine catabolic process 1.928856e-3
GO:0048343 paraxial mesodermal cell fate commitment 1.934306e-3
GO:0015874 norepinephrine transport 1.934306e-3
GO:0000956 nuclear-transcribed mRNA catabolic process 1.935167e-3
GO:0042255 ribosome assembly 1.936637e-3
GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions 1.953763e-3
GO:0051865 protein autoubiquitination 1.959471e-3
GO:0071421 manganese ion transmembrane transport 1.971519e-3
GO:0030826 regulation of cGMP biosynthetic process 1.981362e-3
GO:0071496 cellular response to external stimulus 1.981736e-3
GO:0030903 notochord development 2.007122e-3
GO:0050779 RNA destabilization 2.110076e-3
GO:0035518 histone H2A monoubiquitination 2.116900e-3
GO:0000089 mitotic metaphase 2.126739e-3
GO:0006090 pyruvate metabolic process 2.223841e-3
GO:0006668 sphinganine-1-phosphate metabolic process 2.236321e-3
GO:0031284 positive regulation of guanylate cyclase activity 2.236321e-3
GO:0043174 nucleoside salvage 2.263628e-3
GO:0033683 nucleotide-excision repair, DNA incision 2.270479e-3
GO:0044236 multicellular organismal metabolic process 2.335133e-3
GO:0045948 positive regulation of translational initiation 2.338979e-3
GO:0007184 SMAD protein import into nucleus 2.353658e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0006351 transcription, DNA-dependent 1.383099e-8
GO:0032774 RNA biosynthetic process 1.982967e-8
GO:0046847 filopodium assembly 3.784843e-8
GO:0045814 negative regulation of gene expression, epigenetic 2.156744e-7
GO:0045922 negative regulation of fatty acid metabolic process 2.332677e-7
GO:0031440 regulation of mRNA 3'-end processing 2.567414e-7
GO:0031442 positive regulation of mRNA 3'-end processing 3.220532e-7
GO:0030035 microspike assembly 3.365513e-7
GO:0034227 tRNA thio-modification 3.857285e-7
GO:0045792 negative regulation of cell size 3.954850e-7
GO:0010467 gene expression 4.746834e-7
GO:0006346 methylation-dependent chromatin silencing 1.426943e-6
GO:0032007 negative regulation of TOR signaling cascade 1.790440e-6
GO:0046785 microtubule polymerization 1.983779e-6
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2.221566e-6
GO:0061014 positive regulation of mRNA catabolic process 2.350824e-6
GO:0001885 endothelial cell development 3.130311e-6
GO:0001892 embryonic placenta development 5.327106e-6
GO:0022009 central nervous system vasculogenesis 5.356954e-6
GO:0048255 mRNA stabilization 6.350466e-6
GO:0034142 toll-like receptor 4 signaling pathway 6.554619e-6
GO:0010424 DNA methylation on cytosine within a CG sequence 6.673356e-6
GO:0002221 pattern recognition receptor signaling pathway 9.215430e-6
GO:0045908 negative regulation of vasodilation 9.568868e-6
GO:0034505 tooth mineralization 1.468279e-5
GO:0002758 innate immune response-activating signal transduction 1.854845e-5
GO:0030219 megakaryocyte differentiation 1.882964e-5
GO:0002642 positive regulation of immunoglobulin biosynthetic process 1.998772e-5
GO:0090083 regulation of inclusion body assembly 2.109286e-5
GO:0090084 negative regulation of inclusion body assembly 2.182729e-5
GO:2000251 positive regulation of actin cytoskeleton reorganization 2.517166e-5
GO:0002224 toll-like receptor signaling pathway 3.137801e-5
GO:0060712 spongiotrophoblast layer development 3.380260e-5
GO:0002218 activation of innate immune response 3.491541e-5
GO:0007288 sperm axoneme assembly 3.533215e-5
GO:0035313 wound healing, spreading of epidermal cells 3.755544e-5
GO:0032776 DNA methylation on cytosine 3.869937e-5
GO:0045717 negative regulation of fatty acid biosynthetic process 3.957363e-5
GO:0018022 peptidyl-lysine methylation 4.264442e-5
GO:0010312 detoxification of zinc ion 4.282926e-5
GO:0090234 regulation of kinetochore assembly 4.783348e-5
GO:0090169 regulation of spindle assembly 4.783348e-5
GO:0010216 maintenance of DNA methylation 5.108377e-5
GO:0006558 L-phenylalanine metabolic process 5.108377e-5
GO:0014045 establishment of endothelial blood-brain barrier 5.166059e-5
GO:0090086 negative regulation of protein deubiquitination 5.167114e-5
GO:0009648 photoperiodism 5.218590e-5
GO:0046322 negative regulation of fatty acid oxidation 5.878922e-5
GO:0016070 RNA metabolic process 7.220839e-5
GO:0044319 wound healing, spreading of cells 7.222535e-5
GO:0045647 negative regulation of erythrocyte differentiation 8.892322e-5
GO:0032012 regulation of ARF protein signal transduction 9.138330e-5
GO:0043153 entrainment of circadian clock by photoperiod 1.029821e-4
GO:0043314 negative regulation of neutrophil degranulation 1.150862e-4
GO:0043301 negative regulation of leukocyte degranulation 1.188198e-4
GO:0045064 T-helper 2 cell differentiation 1.211470e-4
GO:0002098 tRNA wobble uridine modification 1.239559e-4
GO:0033239 negative regulation of cellular amine metabolic process 1.264807e-4
GO:0050685 positive regulation of mRNA processing 1.289193e-4
GO:0006559 L-phenylalanine catabolic process 1.343357e-4
GO:0046498 S-adenosylhomocysteine metabolic process 1.384780e-4
GO:0001957 intramembranous ossification 1.421590e-4
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 1.508502e-4
GO:0002268 follicular dendritic cell differentiation 1.508502e-4
GO:0006342 chromatin silencing 1.566454e-4
GO:0006268 DNA unwinding involved in replication 1.590099e-4
GO:0045019 negative regulation of nitric oxide biosynthetic process 1.593356e-4
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 1.623513e-4
GO:0060066 oviduct development 1.623513e-4
GO:0043320 natural killer cell degranulation 1.627369e-4
GO:0072124 regulation of glomerular mesangial cell proliferation 1.651641e-4
GO:0010735 positive regulation of transcription via serum response element binding 1.752367e-4
GO:0045948 positive regulation of translational initiation 1.762377e-4
GO:0018065 protein-cofactor linkage 2.018348e-4
GO:2000015 regulation of determination of dorsal identity 2.056899e-4
GO:0071506 cellular response to mycophenolic acid 2.108455e-4
GO:0072126 positive regulation of glomerular mesangial cell proliferation 2.108455e-4
GO:0060010 Sertoli cell fate commitment 2.108455e-4
GO:0045415 negative regulation of interleukin-8 biosynthetic process 2.141408e-4
GO:0033590 response to cobalamin 2.141408e-4
GO:0007144 female meiosis I 2.141408e-4
GO:0018195 peptidyl-arginine modification 2.289678e-4
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 2.506618e-4
GO:0001835 blastocyst hatching 2.535244e-4
GO:0018198 peptidyl-cysteine modification 2.666544e-4
GO:0021877 forebrain neuron fate commitment 2.669934e-4
GO:0034446 substrate adhesion-dependent cell spreading 2.672646e-4
GO:0031999 negative regulation of fatty acid beta-oxidation 2.680992e-4
GO:0008295 spermidine biosynthetic process 2.750419e-4
GO:0090304 nucleic acid metabolic process 2.804562e-4
GO:0000045 autophagic vacuole assembly 2.863983e-4
GO:0045987 positive regulation of smooth muscle contraction 2.887805e-4
GO:0010985 negative regulation of lipoprotein particle clearance 3.137128e-4
GO:0018205 peptidyl-lysine modification 3.361224e-4
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 3.482159e-4
GO:0017156 calcium ion-dependent exocytosis 3.485974e-4
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 3.771538e-4
GO:0033159 negative regulation of protein import into nucleus, translocation 3.783650e-4
GO:0035021 negative regulation of Rac protein signal transduction 3.800839e-4
GO:0007412 axon target recognition 3.800839e-4
GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation 3.926037e-4
GO:0070935 3'-UTR-mediated mRNA stabilization 3.926037e-4
GO:0060709 glycogen cell development involved in embryonic placenta development 4.116515e-4
GO:2000249 regulation of actin cytoskeleton reorganization 4.225398e-4
GO:0032964 collagen biosynthetic process 4.464065e-4
GO:0031109 microtubule polymerization or depolymerization 4.705836e-4
GO:0043951 negative regulation of cAMP-mediated signaling 4.919669e-4
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 4.919669e-4
GO:0018023 peptidyl-lysine trimethylation 4.919669e-4
GO:0002755 MyD88-dependent toll-like receptor signaling pathway 4.919669e-4
GO:0051103 DNA ligation involved in DNA repair 5.146100e-4
GO:0006266 DNA ligation 5.190791e-4
GO:0010984 regulation of lipoprotein particle clearance 5.248770e-4
GO:0043313 regulation of neutrophil degranulation 5.262705e-4
GO:0016567 protein ubiquitination 5.559537e-4
GO:0021695 cerebellar cortex development 5.781014e-4
GO:0006094 gluconeogenesis 5.823243e-4
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 6.244251e-4
GO:0018009 N-terminal peptidyl-L-cysteine N-palmitoylation 6.244251e-4
GO:0070925 organelle assembly 6.557350e-4
GO:0060696 regulation of phospholipid catabolic process 6.684840e-4
GO:0014056 regulation of acetylcholine secretion 6.707435e-4
GO:0034382 chylomicron remnant clearance 6.731357e-4
GO:0006363 termination of RNA polymerase I transcription 6.789401e-4
GO:0001829 trophectodermal cell differentiation 6.967352e-4
GO:0072054 renal outer medulla development 6.980526e-4
GO:0035246 peptidyl-arginine N-methylation 7.155623e-4
GO:0021681 cerebellar granular layer development 7.456043e-4
GO:0046039 GTP metabolic process 7.539761e-4
GO:0034959 endothelin maturation 7.573316e-4
GO:0010814 substance P catabolic process 7.573316e-4
GO:0010816 calcitonin catabolic process 7.573316e-4
GO:0018216 peptidyl-arginine methylation 7.621655e-4
GO:0033119 negative regulation of RNA splicing 7.760353e-4
GO:0000212 meiotic spindle organization 8.169090e-4
GO:0045446 endothelial cell differentiation 8.183568e-4
GO:0001570 vasculogenesis 8.233191e-4
GO:0046940 nucleoside monophosphate phosphorylation 8.641016e-4
GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway 8.641016e-4
GO:0035912 dorsal aorta morphogenesis 8.641016e-4
GO:0030038 contractile actin filament bundle assembly 8.641016e-4
GO:0018192 enzyme active site formation via L-cysteine persulfide 8.667959e-4
GO:0023035 CD40 signaling pathway 8.667959e-4
GO:0008594 photoreceptor cell morphogenesis 8.667959e-4
GO:0035886 vascular smooth muscle cell differentiation 8.738357e-4
GO:0061084 negative regulation of protein refolding 8.943463e-4
GO:0010891 negative regulation of sequestering of triglyceride 8.976396e-4
GO:0060484 lung-associated mesenchyme development 9.129893e-4
GO:0034645 cellular macromolecule biosynthetic process 9.171312e-4
GO:0043243 positive regulation of protein complex disassembly 9.287349e-4
GO:0061028 establishment of endothelial barrier 9.623993e-4
GO:0060947 cardiac vascular smooth muscle cell differentiation 9.746720e-4
GO:0061001 regulation of dendritic spine morphogenesis 9.789144e-4
GO:0007143 female meiosis 1.024207e-3
GO:0035813 regulation of renal sodium excretion 1.030171e-3
GO:0072053 renal inner medulla development 1.064743e-3
GO:0016236 macroautophagy 1.070185e-3
GO:0050684 regulation of mRNA processing 1.078990e-3
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1.113793e-3
GO:0006361 transcription initiation from RNA polymerase I promoter 1.113793e-3
GO:0016568 chromatin modification 1.117152e-3
GO:0042538 hyperosmotic salinity response 1.121042e-3
GO:0050779 RNA destabilization 1.142520e-3
GO:0061013 regulation of mRNA catabolic process 1.150296e-3
GO:0044062 regulation of excretion 1.150296e-3
GO:0018199 peptidyl-glutamine modification 1.155679e-3
GO:0032446 protein modification by small protein conjugation 1.173936e-3
GO:0001825 blastocyst formation 1.235353e-3
GO:0009059 macromolecule biosynthetic process 1.267507e-3
GO:0007129 synapsis 1.272660e-3
GO:0070192 chromosome organization involved in meiosis 1.273312e-3
GO:0090116 C-5 methylation of cytosine 1.352416e-3
GO:0072284 metanephric S-shaped body morphogenesis 1.352416e-3
GO:0072278 metanephric comma-shaped body morphogenesis 1.352416e-3
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 1.352416e-3
GO:0010718 positive regulation of epithelial to mesenchymal transition 1.383748e-3
GO:0001890 placenta development 1.396078e-3
GO:0006184 GTP catabolic process 1.410443e-3
GO:0018293 protein-FAD linkage 1.417611e-3
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 1.417611e-3
GO:0010889 regulation of sequestering of triglyceride 1.435054e-3
GO:0016188 synaptic vesicle maturation 1.444796e-3
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 1.447378e-3
GO:0045819 positive regulation of glycogen catabolic process 1.495920e-3
GO:0032508 DNA duplex unwinding 1.508289e-3
GO:0003158 endothelium development 1.524480e-3
GO:0043653 mitochondrial fragmentation involved in apoptosis 1.532815e-3
GO:0060534 trachea cartilage development 1.554601e-3
GO:0001886 endothelial cell morphogenesis 1.556124e-3
GO:0050995 negative regulation of lipid catabolic process 1.567004e-3
GO:0035855 megakaryocyte development 1.570027e-3
GO:0048368 lateral mesoderm development 1.570027e-3
GO:0006572 tyrosine catabolic process 1.674680e-3
GO:0034969 histone arginine methylation 1.693345e-3
GO:0060012 synaptic transmission, glycinergic 1.714755e-3
GO:0046755 non-lytic virus budding 1.714755e-3
GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine 1.714755e-3
GO:0002077 acrosome matrix dispersal 1.714755e-3
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 1.813991e-3
GO:0001834 trophectodermal cell proliferation 1.813991e-3
GO:0010614 negative regulation of cardiac muscle hypertrophy 1.814195e-3
GO:0060976 coronary vasculature development 1.849924e-3
GO:0010900 negative regulation of phosphatidylcholine catabolic process 1.852743e-3
GO:0051276 chromosome organization 1.873226e-3
GO:0070286 axonemal dynein complex assembly 1.882138e-3
GO:0071529 cementum mineralization 1.882138e-3
GO:0006449 regulation of translational termination 1.882138e-3
GO:0035082 axoneme assembly 1.931471e-3
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 1.932110e-3
GO:0010452 histone H3-K36 methylation 2.046709e-3
GO:0070383 DNA cytosine deamination 2.101485e-3
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 2.101485e-3
GO:0010529 negative regulation of transposition 2.101485e-3
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 2.101485e-3
GO:0060047 heart contraction 2.109192e-3
GO:0071299 cellular response to vitamin A 2.117390e-3
GO:0002432 granuloma formation 2.125061e-3
GO:0033002 muscle cell proliferation 2.149151e-3
GO:0035329 hippo signaling cascade 2.155467e-3
GO:0008078 mesodermal cell migration 2.201901e-3
GO:0038007 netrin-activated signaling pathway 2.241848e-3
GO:0051013 microtubule severing 2.241848e-3
GO:0070474 positive regulation of uterine smooth muscle contraction 2.358594e-3
GO:0061034 olfactory bulb mitral cell layer development 2.358594e-3
GO:0032922 circadian regulation of gene expression 2.367816e-3
GO:0035247 peptidyl-arginine omega-N-methylation 2.371050e-3
GO:0030865 cortical cytoskeleton organization 2.401436e-3
GO:0043401 steroid hormone mediated signaling pathway 2.479392e-3
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 2.535567e-3
GO:0010458 exit from mitosis 2.535567e-3
GO:0072061 inner medullary collecting duct development 2.617580e-3
GO:2000017 positive regulation of determination of dorsal identity 2.617580e-3
GO:2001037 positive regulation of tongue muscle cell differentiation 2.617580e-3
GO:0072060 outer medullary collecting duct development 2.617580e-3
GO:0046882 negative regulation of follicle-stimulating hormone secretion 2.617580e-3
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 2.617580e-3
GO:0072109 glomerular mesangium development 2.651361e-3
GO:0007340 acrosome reaction 2.721628e-3
GO:0048295 positive regulation of isotype switching to IgE isotypes 2.737535e-3
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 2.737535e-3
GO:0033158 regulation of protein import into nucleus, translocation 2.784428e-3
GO:0006139 nucleobase-containing compound metabolic process 2.804567e-3
GO:0072070 loop of Henle development 2.808120e-3
GO:0051586 positive regulation of dopamine uptake 2.863584e-3
GO:0035659 Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells 2.863584e-3
GO:0032915 positive regulation of transforming growth factor beta2 production 2.863584e-3
GO:0014719 satellite cell activation 2.863584e-3
GO:0042304 regulation of fatty acid biosynthetic process 2.963221e-3
GO:0007352 zygotic specification of dorsal/ventral axis 2.969716e-3
GO:0050994 regulation of lipid catabolic process 3.060329e-3
GO:0032392 DNA geometric change 3.100972e-3
GO:0006325 chromatin organization 3.112957e-3
GO:0097039 protein linear polyubiquitination 3.145354e-3
GO:0040029 regulation of gene expression, epigenetic 3.152018e-3
GO:0018105 peptidyl-serine phosphorylation 3.194642e-3
GO:0015966 diadenosine tetraphosphate biosynthetic process 3.218319e-3
GO:0060385 axonogenesis involved in innervation 3.218319e-3
GO:0015887 pantothenate transmembrane transport 3.218319e-3
GO:0015878 biotin transport 3.218319e-3
GO:0006409 tRNA export from nucleus 3.218319e-3
GO:0060764 cell-cell signaling involved in mammary gland development 3.370090e-3
GO:0031129 inductive cell-cell signaling 3.370090e-3
GO:0006756 AMP phosphorylation 3.370090e-3
GO:0043968 histone H2A acetylation 3.403567e-3
GO:0071300 cellular response to retinoic acid 3.420373e-3
GO:0010288 response to lead ion 3.536331e-3
GO:0046590 embryonic leg morphogenesis 3.547866e-3
GO:0008050 female courtship behavior 3.547866e-3
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 3.599703e-3
GO:0060419 heart growth 3.612777e-3
GO:0000089 mitotic metaphase 3.635000e-3
GO:0055017 cardiac muscle tissue growth 3.662747e-3
GO:0071321 cellular response to cGMP 3.674942e-3
GO:0060048 cardiac muscle contraction 3.733842e-3
GO:0010887 negative regulation of cholesterol storage 3.762301e-3
GO:0060461 right lung morphogenesis 3.768874e-3
GO:0090131 mesenchyme migration 3.768874e-3
GO:0014822 detection of wounding 3.768874e-3
GO:0060446 branching involved in open tracheal system development 3.768874e-3
GO:0048613 embryonic ectodermal digestive tract morphogenesis 3.768874e-3
GO:0048371 lateral mesodermal cell differentiation 3.768874e-3
GO:0042373 vitamin K metabolic process 3.862539e-3
GO:0002886 regulation of myeloid leukocyte mediated immunity 3.899702e-3
GO:0033233 regulation of protein sumoylation 3.945665e-3
GO:0072205 metanephric collecting duct development 3.945665e-3
GO:0051693 actin filament capping 4.083156e-3
GO:0007509 mesoderm migration involved in gastrulation 4.162681e-3
GO:0061002 negative regulation of dendritic spine morphogenesis 4.198598e-3
GO:0010565 regulation of cellular ketone metabolic process 4.276841e-3
GO:0009798 axis specification 4.314787e-3
GO:0060535 trachea cartilage morphogenesis 4.348128e-3
GO:0051001 negative regulation of nitric-oxide synthase activity 4.348128e-3
GO:0045916 negative regulation of complement activation 4.352044e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 4.352044e-3
GO:0021697 cerebellar cortex formation 4.392561e-3
GO:0060343 trabecula formation 4.615522e-3
GO:0051005 negative regulation of lipoprotein lipase activity 4.661700e-3
GO:0031507 heterochromatin formation 4.690402e-3
GO:0042268 regulation of cytolysis 4.710383e-3
GO:0016926 protein desumoylation 4.710383e-3
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 4.769309e-3
GO:0021707 cerebellar granule cell differentiation 4.844770e-3
GO:0008535 respiratory chain complex IV assembly 4.990679e-3
GO:0031558 induction of apoptosis in response to chemical stimulus 4.990679e-3
GO:0060160 negative regulation of dopamine receptor signaling pathway 5.117370e-3
GO:0030421 defecation 5.117370e-3
GO:0008216 spermidine metabolic process 5.117370e-3
GO:0008063 Toll signaling pathway 5.117370e-3
GO:0051176 positive regulation of sulfur metabolic process 5.193896e-3
GO:0051451 myoblast migration 5.193896e-3
GO:0035441 cell migration involved in vasculogenesis 5.193896e-3
GO:0043300 regulation of leukocyte degranulation 5.220103e-3
GO:0090224 regulation of spindle organization 5.257895e-3
GO:0006513 protein monoubiquitination 5.407891e-3
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 5.481174e-3
GO:0051323 metaphase 5.529872e-3
GO:0051238 sequestering of metal ion 5.681804e-3
GO:0097012 response to granulocyte macrophage colony-stimulating factor stimulus 5.681804e-3
GO:0006779 porphyrin-containing compound biosynthetic process 5.739874e-3
GO:2000383 regulation of ectoderm development 5.952500e-3
GO:0051252 regulation of RNA metabolic process 6.097924e-3
GO:0072110 glomerular mesangial cell proliferation 6.135985e-3
GO:0007168 receptor guanylyl cyclase signaling pathway 6.135985e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 6.160893e-3
GO:0046929 negative regulation of neurotransmitter secretion 6.208343e-3
GO:0014040 positive regulation of Schwann cell differentiation 6.208343e-3
GO:0006685 sphingomyelin catabolic process 6.208343e-3
GO:0061046 regulation of branching involved in lung morphogenesis 6.253376e-3
GO:0046320 regulation of fatty acid oxidation 6.433359e-3
GO:0016090 prenol metabolic process 6.464211e-3
GO:0051725 protein de-ADP-ribosylation 6.549966e-3
GO:0070079 histone H4-R3 demethylation 6.549966e-3
GO:0070078 histone H3-R2 demethylation 6.549966e-3
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 6.549966e-3
GO:0000722 telomere maintenance via recombination 6.549966e-3
GO:0060482 lobar bronchus development 6.566937e-3
GO:0032119 sequestering of zinc ion 6.684441e-3
GO:0010468 regulation of gene expression 6.710354e-3
GO:0072236 metanephric loop of Henle development 6.842263e-3
GO:0071422 succinate transmembrane transport 6.930547e-3
GO:0000415 negative regulation of histone H3-K36 methylation 6.930547e-3
GO:0035269 protein O-linked mannosylation 6.930547e-3
GO:0002439 chronic inflammatory response to antigenic stimulus 6.973811e-3
GO:0016574 histone ubiquitination 7.236604e-3
GO:0032006 regulation of TOR signaling cascade 7.297150e-3
GO:0048227 plasma membrane to endosome transport 7.306280e-3
GO:0046604 positive regulation of mitotic centrosome separation 7.306280e-3
GO:0065002 intracellular protein transmembrane transport 7.306280e-3
GO:0032065 cortical protein anchoring 7.306280e-3
GO:0021528 commissural neuron differentiation in spinal cord 7.306280e-3
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 7.356229e-3
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 7.356229e-3
GO:0051026 chiasma assembly 7.356229e-3
GO:0006546 glycine catabolic process 7.356229e-3
GO:2000426 negative regulation of apoptotic cell clearance 7.383776e-3
GO:0033147 negative regulation of estrogen receptor signaling pathway 7.383776e-3
GO:0071480 cellular response to gamma radiation 7.436457e-3
GO:0072164 mesonephric tubule development 7.667721e-3
GO:0019217 regulation of fatty acid metabolic process 7.674399e-3
GO:0046967 cytosol to ER transport 7.763099e-3
GO:0035611 protein branching point deglutamylation 7.763099e-3
GO:0019060 intracellular transport of viral proteins in host cell 7.763099e-3
GO:0034134 toll-like receptor 2 signaling pathway 7.763099e-3
GO:0043206 fibril organization 7.841618e-3
GO:0042267 natural killer cell mediated cytotoxicity 8.040959e-3
GO:0048384 retinoic acid receptor signaling pathway 8.045365e-3
GO:0060038 cardiac muscle cell proliferation 8.046460e-3
GO:0002002 regulation of angiotensin levels in blood 8.046659e-3
GO:0046499 S-adenosylmethioninamine metabolic process 8.046659e-3
GO:0046939 nucleotide phosphorylation 8.114979e-3
GO:0031365 N-terminal protein amino acid modification 8.131209e-3
GO:0060997 dendritic spine morphogenesis 8.164857e-3
GO:0021892 cerebral cortex GABAergic interneuron differentiation 8.232239e-3
GO:0015884 folic acid transport 8.357986e-3
GO:0051639 actin filament network formation 8.466740e-3
GO:0045905 positive regulation of translational termination 8.466740e-3
GO:2000384 negative regulation of ectoderm development 8.466740e-3
GO:0006452 translational frameshifting 8.466740e-3
GO:0045343 regulation of MHC class I biosynthetic process 8.466740e-3
GO:0045901 positive regulation of translational elongation 8.466740e-3
GO:0061383 trabecula morphogenesis 8.482957e-3
GO:0018193 peptidyl-amino acid modification 8.534465e-3
GO:0006474 N-terminal protein amino acid acetylation 8.644945e-3
GO:0045112 integrin biosynthetic process 8.727476e-3
GO:0060346 bone trabecula formation 8.816831e-3
GO:0045920 negative regulation of exocytosis 8.930372e-3
GO:0031331 positive regulation of cellular catabolic process 9.084410e-3
GO:0022406 membrane docking 9.111513e-3
GO:0007619 courtship behavior 9.152667e-3
GO:0010950 positive regulation of endopeptidase activity 9.255239e-3
GO:0021696 cerebellar cortex morphogenesis 9.324438e-3
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 9.375119e-3
GO:0003062 regulation of heart rate by chemical signal 9.375119e-3
GO:0007028 cytoplasm organization 9.375119e-3
GO:0090045 positive regulation of deacetylase activity 9.439651e-3
GO:0070831 basement membrane assembly 9.439651e-3
GO:0006930 substrate-dependent cell migration, cell extension 9.439651e-3
GO:0006391 transcription initiation from mitochondrial promoter 9.439651e-3
GO:0048285 organelle fission 9.473527e-3
GO:0072074 kidney mesenchyme development 9.646339e-3
GO:0090002 establishment of protein localization in plasma membrane 9.799669e-3
GO:0009048 dosage compensation, by inactivation of X chromosome 9.799669e-3
GO:0031272 regulation of pseudopodium assembly 9.927598e-3
GO:0019219 regulation of nucleobase-containing compound metabolic process 9.927711e-3
GO:0010896 regulation of triglyceride catabolic process 9.975564e-3
GO:0007051 spindle organization 1.020429e-2
GO:0032312 regulation of ARF GTPase activity 1.025445e-2
GO:0022614 membrane to membrane docking 1.032666e-2
GO:0002827 positive regulation of T-helper 1 type immune response 1.032666e-2
GO:0030261 chromosome condensation 1.041244e-2
GO:0060180 female mating behavior 1.042964e-2
GO:0033083 regulation of immature T cell proliferation 1.042964e-2
GO:0070836 caveola assembly 1.045727e-2
GO:0032613 interleukin-10 production 1.045727e-2
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 1.050761e-2
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 1.050761e-2
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 1.050761e-2
GO:0072075 metanephric mesenchyme development 1.052305e-2
GO:0046339 diacylglycerol metabolic process 1.062613e-2
GO:0016458 gene silencing 1.063256e-2
GO:0030878 thyroid gland development 1.075358e-2
GO:0051171 regulation of nitrogen compound metabolic process 1.101817e-2
GO:0043045 DNA methylation involved in embryo development 1.143014e-2
GO:0006383 transcription from RNA polymerase III promoter 1.143014e-2
GO:0046685 response to arsenic-containing substance 1.153385e-2
GO:0090150 establishment of protein localization in membrane 1.159253e-2
GO:0051301 cell division 1.199280e-2
GO:0043088 regulation of Cdc42 GTPase activity 1.203659e-2
GO:0046341 CDP-diacylglycerol metabolic process 1.209027e-2
GO:0000729 DNA double-strand break processing 1.209027e-2
GO:0031998 regulation of fatty acid beta-oxidation 1.228343e-2
GO:0070305 response to cGMP 1.228500e-2
GO:0008612 peptidyl-lysine modification to hypusine 1.228500e-2
GO:0000087 M phase of mitotic cell cycle 1.231544e-2
GO:0010878 cholesterol storage 1.256585e-2
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 1.256585e-2
GO:0033566 gamma-tubulin complex localization 1.256585e-2
GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 1.257107e-2
GO:0045833 negative regulation of lipid metabolic process 1.275706e-2
GO:0072040 negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis 1.307269e-2
GO:0006657 CDP-choline pathway 1.307333e-2
GO:0045933 positive regulation of muscle contraction 1.317288e-2
GO:0035307 positive regulation of protein dephosphorylation 1.341495e-2
GO:0051254 positive regulation of RNA metabolic process 1.347959e-2
GO:0071636 positive regulation of transforming growth factor beta production 1.360727e-2
GO:0043201 response to leucine 1.361085e-2
GO:0061088 regulation of sequestering of zinc ion 1.361085e-2
GO:0021683 cerebellar granular layer morphogenesis 1.389658e-2
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1.399866e-2
GO:0007183 SMAD protein complex assembly 1.399866e-2
GO:0006778 porphyrin-containing compound metabolic process 1.403045e-2
GO:0090130 tissue migration 1.403243e-2
GO:0045084 positive regulation of interleukin-12 biosynthetic process 1.406855e-2
GO:0043488 regulation of mRNA stability 1.407644e-2
GO:0043949 regulation of cAMP-mediated signaling 1.408293e-2
GO:0060711 labyrinthine layer development 1.408691e-2
GO:0051220 cytoplasmic sequestering of protein 1.412390e-2
GO:2000772 regulation of cellular senescence 1.415053e-2
GO:0042994 cytoplasmic sequestering of transcription factor 1.415053e-2
GO:0033013 tetrapyrrole metabolic process 1.425990e-2
GO:0007614 short-term memory 1.426379e-2
GO:0006213 pyrimidine nucleoside metabolic process 1.427973e-2
GO:0006288 base-excision repair, DNA ligation 1.445400e-2
GO:0071260 cellular response to mechanical stimulus 1.467582e-2
GO:0042275 error-free postreplication DNA repair 1.490737e-2
GO:0035520 monoubiquitinated protein deubiquitination 1.490737e-2
GO:0045345 positive regulation of MHC class I biosynthetic process 1.490737e-2
GO:0035461 vitamin transmembrane transport 1.490737e-2
GO:0031508 centromeric heterochromatin formation 1.490737e-2
GO:0072003 kidney rudiment formation 1.501243e-2
GO:0060177 regulation of angiotensin metabolic process 1.505286e-2
GO:0048477 oogenesis 1.508557e-2
GO:0007127 meiosis I 1.548342e-2
GO:0032098 regulation of appetite 1.559362e-2
GO:0090280 positive regulation of calcium ion import 1.559460e-2
GO:0010388 cullin deneddylation 1.559460e-2
GO:0071316 cellular response to nicotine 1.559460e-2
GO:0060299 negative regulation of sarcomere organization 1.582327e-2
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 1.582327e-2
GO:0070345 negative regulation of fat cell proliferation 1.582327e-2
GO:0042840 D-glucuronate catabolic process 1.582327e-2
GO:0070086 ubiquitin-dependent endocytosis 1.582327e-2
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 1.582327e-2
GO:0042703 menstruation 1.582327e-2
GO:0009234 menaquinone biosynthetic process 1.582327e-2
GO:0032782 bile acid secretion 1.582327e-2
GO:0019101 female somatic sex determination 1.582327e-2
GO:0003096 renal sodium ion transport 1.582327e-2
GO:0033314 mitotic cell cycle DNA replication checkpoint 1.582327e-2
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 1.606751e-2
GO:0051156 glucose 6-phosphate metabolic process 1.629418e-2
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.629418e-2
GO:0043487 regulation of RNA stability 1.631245e-2
GO:0000738 DNA catabolic process, exonucleolytic 1.651965e-2
GO:0007386 compartment pattern specification 1.651965e-2
GO:0055118 negative regulation of cardiac muscle contraction 1.651965e-2
GO:0001955 blood vessel maturation 1.651965e-2
GO:0033210 leptin-mediated signaling pathway 1.658666e-2
GO:0033617 mitochondrial respiratory chain complex IV assembly 1.658666e-2
GO:0046452 dihydrofolate metabolic process 1.658666e-2