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Novel motif:2

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name:motif2_GCTGGAGG

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 8.290525e-14
GO:0046628 positive regulation of insulin receptor signaling pathway 4.182512e-12
GO:0060033 anatomical structure regression 2.589211e-11
GO:0010984 regulation of lipoprotein particle clearance 4.355080e-11
GO:0060351 cartilage development involved in endochondral bone morphogenesis 6.285619e-11
GO:0035814 negative regulation of renal sodium excretion 6.291177e-11
GO:0010625 positive regulation of Schwann cell proliferation 7.766284e-11
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 4.623185e-10
GO:0050902 leukocyte adhesive activation 4.623185e-10
GO:2000467 positive regulation of glycogen (starch) synthase activity 4.722854e-10
GO:2000465 regulation of glycogen (starch) synthase activity 1.086347e-9
GO:0008078 mesodermal cell migration 2.695714e-9
GO:0035104 positive regulation of transcription via sterol regulatory element binding 5.564215e-9
GO:0010624 regulation of Schwann cell proliferation 8.337830e-9
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 9.835837e-9
GO:0043491 protein kinase B signaling cascade 1.826353e-8
GO:0003009 skeletal muscle contraction 2.279822e-8
GO:0019884 antigen processing and presentation of exogenous antigen 4.832481e-8
GO:0090031 positive regulation of steroid hormone biosynthetic process 5.541944e-8
GO:0045415 negative regulation of interleukin-8 biosynthetic process 7.381499e-8
GO:0032933 SREBP-mediated signaling pathway 7.480128e-8
GO:0006884 cell volume homeostasis 7.946269e-8
GO:0010985 negative regulation of lipoprotein particle clearance 8.136397e-8
GO:0034505 tooth mineralization 1.049544e-7
GO:0071460 cellular response to cell-matrix adhesion 1.147274e-7
GO:0043206 fibril organization 1.245255e-7
GO:0007522 visceral muscle development 1.854908e-7
GO:0046626 regulation of insulin receptor signaling pathway 2.495430e-7
GO:0019048 virus-host interaction 3.268683e-7
GO:0060251 regulation of glial cell proliferation 3.724807e-7
GO:0031444 slow-twitch skeletal muscle fiber contraction 3.789286e-7
GO:0032964 collagen biosynthetic process 4.188880e-7
GO:0002268 follicular dendritic cell differentiation 5.139985e-7
GO:0042074 cell migration involved in gastrulation 5.302732e-7
GO:0006349 regulation of gene expression by genetic imprinting 5.454143e-7
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 5.592006e-7
GO:0002478 antigen processing and presentation of exogenous peptide antigen 8.289140e-7
GO:0040040 thermosensory behavior 8.586765e-7
GO:0003062 regulation of heart rate by chemical signal 1.089680e-6
GO:0010821 regulation of mitochondrion organization 1.194993e-6
GO:0050779 RNA destabilization 1.198558e-6
GO:0001880 Mullerian duct regression 1.334187e-6
GO:0006544 glycine metabolic process 1.373367e-6
GO:0060349 bone morphogenesis 1.440675e-6
GO:0045908 negative regulation of vasodilation 1.442388e-6
GO:0048298 positive regulation of isotype switching to IgA isotypes 1.451250e-6
GO:0060370 susceptibility to T cell mediated cytotoxicity 1.611889e-6
GO:0006706 steroid catabolic process 1.979142e-6
GO:0007509 mesoderm migration involved in gastrulation 2.171464e-6
GO:0033209 tumor necrosis factor-mediated signaling pathway 2.398097e-6
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 2.466475e-6
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 2.716998e-6
GO:0009155 purine deoxyribonucleotide catabolic process 2.806131e-6
GO:0030225 macrophage differentiation 2.993157e-6
GO:0002315 marginal zone B cell differentiation 3.976414e-6
GO:0045064 T-helper 2 cell differentiation 3.976414e-6
GO:0006261 DNA-dependent DNA replication 4.011697e-6
GO:0060348 bone development 4.087904e-6
GO:0045109 intermediate filament organization 4.590602e-6
GO:0010982 regulation of high-density lipoprotein particle clearance 5.778834e-6
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 6.380024e-6
GO:0002906 negative regulation of mature B cell apoptosis 6.380024e-6
GO:0006853 carnitine shuttle 6.500280e-6
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 6.669172e-6
GO:0045725 positive regulation of glycogen biosynthetic process 7.762429e-6
GO:0046339 diacylglycerol metabolic process 7.958857e-6
GO:0015816 glycine transport 8.822820e-6
GO:0051561 elevation of mitochondrial calcium ion concentration 9.217380e-6
GO:0043542 endothelial cell migration 9.757247e-6
GO:0002886 regulation of myeloid leukocyte mediated immunity 9.984127e-6
GO:0046314 phosphocreatine biosynthetic process 1.045866e-5
GO:0030198 extracellular matrix organization 1.147761e-5
GO:0030851 granulocyte differentiation 1.262099e-5
GO:0006707 cholesterol catabolic process 1.270143e-5
GO:0090311 regulation of protein deacetylation 1.304156e-5
GO:0035811 negative regulation of urine volume 1.314227e-5
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 1.373238e-5
GO:0031063 regulation of histone deacetylation 1.440046e-5
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1.448955e-5
GO:0035691 macrophage migration inhibitory factor signaling pathway 1.610569e-5
GO:0048548 regulation of pinocytosis 1.629265e-5
GO:0051085 chaperone mediated protein folding requiring cofactor 1.631323e-5
GO:0034224 cellular response to zinc ion starvation 1.663944e-5
GO:0060669 embryonic placenta morphogenesis 1.706800e-5
GO:0060350 endochondral bone morphogenesis 1.767654e-5
GO:0060252 positive regulation of glial cell proliferation 1.770258e-5
GO:0035094 response to nicotine 1.775822e-5
GO:0030046 parallel actin filament bundle assembly 1.793640e-5
GO:0045906 negative regulation of vasoconstriction 1.849835e-5
GO:0044062 regulation of excretion 1.907579e-5
GO:0043462 regulation of ATPase activity 1.937959e-5
GO:2000251 positive regulation of actin cytoskeleton reorganization 1.945276e-5
GO:0044236 multicellular organismal metabolic process 2.120026e-5
GO:0019087 transformation of host cell by virus 2.135310e-5
GO:0090199 regulation of release of cytochrome c from mitochondria 2.143177e-5
GO:0033505 floor plate morphogenesis 2.228478e-5
GO:0022038 corpus callosum development 2.355615e-5
GO:0018205 peptidyl-lysine modification 2.441273e-5
GO:0043534 blood vessel endothelial cell migration 2.512377e-5
GO:0048705 skeletal system morphogenesis 2.520898e-5
GO:0035105 sterol regulatory element binding protein import into nucleus 2.589246e-5
GO:0043304 regulation of mast cell degranulation 2.774836e-5
GO:0032863 activation of Rac GTPase activity 2.820118e-5
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 2.823477e-5
GO:0060706 cell differentiation involved in embryonic placenta development 2.845809e-5
GO:0045794 negative regulation of cell volume 2.891639e-5
GO:0019388 galactose catabolic process 2.933844e-5
GO:0009070 serine family amino acid biosynthetic process 2.952824e-5
GO:0002071 glandular epithelial cell maturation 3.066535e-5
GO:0033235 positive regulation of protein sumoylation 3.093410e-5
GO:0060124 positive regulation of growth hormone secretion 3.137851e-5
GO:0070256 negative regulation of mucus secretion 3.174028e-5
GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep 3.174028e-5
GO:0010718 positive regulation of epithelial to mesenchymal transition 3.212570e-5
GO:0043300 regulation of leukocyte degranulation 3.303833e-5
GO:0043088 regulation of Cdc42 GTPase activity 3.379826e-5
GO:0060073 micturition 3.412679e-5
GO:0048627 myoblast development 3.445961e-5
GO:0001909 leukocyte mediated cytotoxicity 3.499256e-5
GO:0060346 bone trabecula formation 3.899215e-5
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 3.905833e-5
GO:0060020 Bergmann glial cell differentiation 3.907661e-5
GO:0071732 cellular response to nitric oxide 3.965025e-5
GO:0006475 internal protein amino acid acetylation 4.042202e-5
GO:0055009 atrial cardiac muscle tissue morphogenesis 4.136803e-5
GO:0060670 branching involved in embryonic placenta morphogenesis 4.148651e-5
GO:0006012 galactose metabolic process 4.239362e-5
GO:0071071 regulation of phospholipid biosynthetic process 4.351959e-5
GO:0044259 multicellular organismal macromolecule metabolic process 4.423528e-5
GO:0010511 regulation of phosphatidylinositol biosynthetic process 4.445383e-5
GO:0070875 positive regulation of glycogen metabolic process 4.523309e-5
GO:0010717 regulation of epithelial to mesenchymal transition 4.618331e-5
GO:0044243 multicellular organismal catabolic process 4.748613e-5
GO:0002017 regulation of blood volume by renal aldosterone 4.971523e-5
GO:0051013 microtubule severing 4.998929e-5
GO:0019064 viral envelope fusion with host membrane 4.998929e-5
GO:0031017 exocrine pancreas development 5.045493e-5
GO:0018277 protein deamination 5.420844e-5
GO:0006353 transcription termination, DNA-dependent 5.426616e-5
GO:0034969 histone arginine methylation 5.695428e-5
GO:0000389 nuclear mRNA 3'-splice site recognition 5.886003e-5
GO:0014848 urinary tract smooth muscle contraction 5.894625e-5
GO:0071072 negative regulation of phospholipid biosynthetic process 6.265631e-5
GO:0070327 thyroid hormone transport 6.316286e-5
GO:0005979 regulation of glycogen biosynthetic process 6.401879e-5
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 6.481718e-5
GO:0015695 organic cation transport 6.755928e-5
GO:0002432 granuloma formation 6.863369e-5
GO:0032012 regulation of ARF protein signal transduction 7.164261e-5
GO:0032963 collagen metabolic process 7.172445e-5
GO:0043487 regulation of RNA stability 7.276667e-5
GO:0018393 internal peptidyl-lysine acetylation 7.781185e-5
GO:0006545 glycine biosynthetic process 7.873351e-5
GO:0032526 response to retinoic acid 7.876315e-5
GO:0071316 cellular response to nicotine 7.987597e-5
GO:0071514 genetic imprinting 8.179285e-5
GO:0090200 positive regulation of release of cytochrome c from mitochondria 8.266279e-5
GO:0010900 negative regulation of phosphatidylcholine catabolic process 8.303033e-5
GO:0006083 acetate metabolic process 8.303033e-5
GO:0090102 cochlea development 8.410720e-5
GO:0050746 regulation of lipoprotein metabolic process 8.442162e-5
GO:0033233 regulation of protein sumoylation 8.503181e-5
GO:0072337 modified amino acid transport 9.038259e-5
GO:0051956 negative regulation of amino acid transport 9.189024e-5
GO:0046814 virion attachment, binding of host cell surface coreceptor 9.230340e-5
GO:0043543 protein acylation 9.379014e-5
GO:0051438 regulation of ubiquitin-protein ligase activity 9.439542e-5
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 9.804416e-5
GO:0006473 protein acetylation 1.000298e-4
GO:0043089 positive regulation of Cdc42 GTPase activity 1.036241e-4
GO:0061144 alveolar secondary septum development 1.041502e-4
GO:0018394 peptidyl-lysine acetylation 1.062318e-4
GO:0035313 wound healing, spreading of epidermal cells 1.071553e-4
GO:0000022 mitotic spindle elongation 1.113703e-4
GO:0009217 purine deoxyribonucleoside triphosphate catabolic process 1.113703e-4
GO:0002636 positive regulation of germinal center formation 1.123739e-4
GO:0000302 response to reactive oxygen species 1.152972e-4
GO:0007020 microtubule nucleation 1.168899e-4
GO:0045932 negative regulation of muscle contraction 1.216087e-4
GO:0048703 embryonic viscerocranium morphogenesis 1.226757e-4
GO:0010988 regulation of low-density lipoprotein particle clearance 1.243825e-4
GO:0043303 mast cell degranulation 1.246192e-4
GO:0001957 intramembranous ossification 1.256428e-4
GO:0060872 semicircular canal development 1.262878e-4
GO:0010822 positive regulation of mitochondrion organization 1.276908e-4
GO:0015696 ammonium transport 1.289013e-4
GO:0055093 response to hyperoxia 1.409607e-4
GO:0006360 transcription from RNA polymerase I promoter 1.469874e-4
GO:0010896 regulation of triglyceride catabolic process 1.486425e-4
GO:0060338 regulation of type I interferon-mediated signaling pathway 1.490739e-4
GO:0015879 carnitine transport 1.532897e-4
GO:0010987 negative regulation of high-density lipoprotein particle clearance 1.566594e-4
GO:0010897 negative regulation of triglyceride catabolic process 1.566594e-4
GO:0009264 deoxyribonucleotide catabolic process 1.567066e-4
GO:0046730 induction of host immune response by virus 1.643184e-4
GO:0032006 regulation of TOR signaling cascade 1.692584e-4
GO:0051546 keratinocyte migration 1.746911e-4
GO:0022617 extracellular matrix disassembly 1.764259e-4
GO:0060711 labyrinthine layer development 1.782011e-4
GO:0035470 positive regulation of vascular wound healing 1.799692e-4
GO:0015747 urate transport 1.799692e-4
GO:0042396 phosphagen biosynthetic process 1.826708e-4
GO:0045799 positive regulation of chromatin assembly or disassembly 1.919391e-4
GO:0035499 carnosine biosynthetic process 1.919391e-4
GO:0002385 mucosal immune response 1.922945e-4
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 2.049130e-4
GO:0006289 nucleotide-excision repair 2.163281e-4
GO:0021508 floor plate formation 2.170435e-4
GO:0048549 positive regulation of pinocytosis 2.170435e-4
GO:0070873 regulation of glycogen metabolic process 2.172931e-4
GO:0051591 response to cAMP 2.188269e-4
GO:0006283 transcription-coupled nucleotide-excision repair 2.197163e-4
GO:0043314 negative regulation of neutrophil degranulation 2.198545e-4
GO:0090086 negative regulation of protein deubiquitination 2.264644e-4
GO:0071242 cellular response to ammonium ion 2.264644e-4
GO:0001977 renal system process involved in regulation of blood volume 2.277851e-4
GO:0035813 regulation of renal sodium excretion 2.298726e-4
GO:0044319 wound healing, spreading of cells 2.394166e-4
GO:0060343 trabecula formation 2.417252e-4
GO:0090103 cochlea morphogenesis 2.430441e-4
GO:0031330 negative regulation of cellular catabolic process 2.449316e-4
GO:0060058 positive regulation of apoptosis involved in mammary gland involution 2.462045e-4
GO:0050965 detection of temperature stimulus involved in sensory perception of pain 2.472364e-4
GO:0006268 DNA unwinding involved in replication 2.485411e-4
GO:0003084 positive regulation of systemic arterial blood pressure 2.507807e-4
GO:0071394 cellular response to testosterone stimulus 2.649494e-4
GO:0070345 negative regulation of fat cell proliferation 2.702236e-4
GO:0071300 cellular response to retinoic acid 2.704430e-4
GO:0061038 uterus morphogenesis 2.859857e-4
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 2.863244e-4
GO:0048242 epinephrine secretion 2.895368e-4
GO:0045575 basophil activation 2.962080e-4
GO:0001694 histamine biosynthetic process 2.962080e-4
GO:0035854 eosinophil fate commitment 3.007002e-4
GO:0030222 eosinophil differentiation 3.007002e-4
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 3.026613e-4
GO:0045217 cell-cell junction maintenance 3.040498e-4
GO:0055010 ventricular cardiac muscle tissue morphogenesis 3.040734e-4
GO:0014832 urinary bladder smooth muscle contraction 3.090949e-4
GO:0090312 positive regulation of protein deacetylation 3.239871e-4
GO:0015939 pantothenate metabolic process 3.260484e-4
GO:0045940 positive regulation of steroid metabolic process 3.279247e-4
GO:0045655 regulation of monocyte differentiation 3.313552e-4
GO:0001300 chronological cell aging 3.334652e-4
GO:0045657 positive regulation of monocyte differentiation 3.428489e-4
GO:0043985 histone H4-R3 methylation 3.455334e-4
GO:0001546 preantral ovarian follicle growth 3.537241e-4
GO:0035732 nitric oxide storage 3.537241e-4
GO:0071638 negative regulation of monocyte chemotactic protein-1 production 3.537241e-4
GO:0035726 common myeloid progenitor cell proliferation 3.537241e-4
GO:0031065 positive regulation of histone deacetylation 3.612537e-4
GO:0060014 granulosa cell differentiation 3.651695e-4
GO:0051005 negative regulation of lipoprotein lipase activity 3.667405e-4
GO:0006458 'de novo' protein folding 3.676541e-4
GO:0002678 positive regulation of chronic inflammatory response 3.716364e-4
GO:0003229 ventricular cardiac muscle tissue development 3.726389e-4
GO:0046732 active induction of host immune response by virus 3.750114e-4
GO:0048708 astrocyte differentiation 3.781844e-4
GO:2000273 positive regulation of receptor activity 4.070064e-4
GO:0002448 mast cell mediated immunity 4.108603e-4
GO:0032425 positive regulation of mismatch repair 4.312923e-4
GO:0021562 vestibulocochlear nerve development 4.312923e-4
GO:0002443 leukocyte mediated immunity 4.359967e-4
GO:0000422 mitochondrion degradation 4.390698e-4
GO:0061304 retinal blood vessel morphogenesis 4.431734e-4
GO:0050861 positive regulation of B cell receptor signaling pathway 4.463763e-4
GO:0002426 immunoglobulin production in mucosal tissue 4.527987e-4
GO:0032793 positive regulation of CREB transcription factor activity 4.542474e-4
GO:0061370 testosterone biosynthetic process 4.636116e-4
GO:0060160 negative regulation of dopamine receptor signaling pathway 4.636116e-4
GO:0050756 fractalkine metabolic process 4.636116e-4
GO:0033595 response to genistein 4.636116e-4
GO:0033006 regulation of mast cell activation involved in immune response 4.677240e-4
GO:0019883 antigen processing and presentation of endogenous antigen 4.720232e-4
GO:0007028 cytoplasm organization 4.857908e-4
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 4.883283e-4
GO:0032796 uropod organization 4.991365e-4
GO:0040015 negative regulation of multicellular organism growth 5.233141e-4
GO:0000084 S phase of mitotic cell cycle 5.294156e-4
GO:0046110 xanthine metabolic process 5.366834e-4
GO:0015858 nucleoside transport 5.398522e-4
GO:0002921 negative regulation of humoral immune response 5.440429e-4
GO:0043585 nose morphogenesis 5.467648e-4
GO:0043353 enucleate erythrocyte differentiation 5.483715e-4
GO:0006354 transcription elongation, DNA-dependent 5.534592e-4
GO:0090205 positive regulation of cholesterol metabolic process 5.551333e-4
GO:0002026 regulation of the force of heart contraction 5.756715e-4
GO:0010310 regulation of hydrogen peroxide metabolic process 5.839312e-4
GO:0031365 N-terminal protein amino acid modification 5.950815e-4
GO:0046718 entry of virus into host cell 6.027952e-4
GO:0017187 peptidyl-glutamic acid carboxylation 6.028748e-4
GO:0061383 trabecula morphogenesis 6.057120e-4
GO:0006423 cysteinyl-tRNA aminoacylation 6.071512e-4
GO:0070943 neutrophil mediated killing of symbiont cell 6.261819e-4
GO:0044258 intestinal lipid catabolic process 6.380331e-4
GO:0018350 protein esterification 6.380331e-4
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 6.380331e-4
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 6.416023e-4
GO:0001560 regulation of cell growth by extracellular stimulus 6.463325e-4
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 6.498817e-4
GO:0048382 mesendoderm development 6.498817e-4
GO:0097045 phosphatidylserine exposure on blood platelet 6.518744e-4
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 6.518744e-4
GO:0034551 mitochondrial respiratory chain complex III assembly 6.518744e-4
GO:0055026 negative regulation of cardiac muscle tissue development 6.534028e-4
GO:0045948 positive regulation of translational initiation 6.545106e-4
GO:0043313 regulation of neutrophil degranulation 6.546162e-4
GO:0051444 negative regulation of ubiquitin-protein ligase activity 6.594737e-4
GO:0007288 sperm axoneme assembly 6.835464e-4
GO:0014002 astrocyte development 6.939723e-4
GO:0060828 regulation of canonical Wnt receptor signaling pathway 6.949872e-4
GO:0016573 histone acetylation 6.961387e-4
GO:0051298 centrosome duplication 7.060467e-4
GO:0031668 cellular response to extracellular stimulus 7.113327e-4
GO:0060707 trophoblast giant cell differentiation 7.227945e-4
GO:0060215 primitive hemopoiesis 7.265923e-4
GO:0050434 positive regulation of viral transcription 7.323097e-4
GO:2000249 regulation of actin cytoskeleton reorganization 7.405408e-4
GO:0023019 signal transduction involved in regulation of gene expression 7.442250e-4
GO:0061143 alveolar primary septum development 7.488866e-4
GO:0044342 type B pancreatic cell proliferation 7.488866e-4
GO:0014053 negative regulation of gamma-aminobutyric acid secretion 7.488866e-4
GO:0010918 positive regulation of mitochondrial membrane potential 7.488866e-4
GO:0006449 regulation of translational termination 7.498258e-4
GO:0002679 respiratory burst involved in defense response 7.808986e-4
GO:0032008 positive regulation of TOR signaling cascade 7.862009e-4
GO:0035247 peptidyl-arginine omega-N-methylation 7.971714e-4
GO:0035573 N-terminal peptidyl-serine trimethylation 8.009578e-4
GO:0035572 N-terminal peptidyl-serine dimethylation 8.009578e-4
GO:0018012 N-terminal peptidyl-alanine trimethylation 8.009578e-4
GO:0018016 N-terminal peptidyl-proline dimethylation 8.009578e-4
GO:0061157 mRNA destabilization 8.186957e-4
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 8.186957e-4
GO:0051693 actin filament capping 8.338417e-4
GO:0033590 response to cobalamin 8.373752e-4
GO:0006117 acetaldehyde metabolic process 8.373752e-4
GO:0006342 chromatin silencing 8.471376e-4
GO:0048320 axial mesoderm formation 8.498768e-4
GO:0060620 regulation of cholesterol import 8.498768e-4
GO:0002513 tolerance induction to self antigen 8.514871e-4
GO:0043299 leukocyte degranulation 8.596481e-4
GO:0090207 regulation of triglyceride metabolic process 8.747442e-4
GO:0051017 actin filament bundle assembly 8.757860e-4
GO:0051788 response to misfolded protein 8.781383e-4
GO:0060621 negative regulation of cholesterol import 8.888903e-4
GO:0032321 positive regulation of Rho GTPase activity 8.891255e-4
GO:0033146 regulation of estrogen receptor signaling pathway 8.936637e-4
GO:0051340 regulation of ligase activity 8.943122e-4
GO:0050747 positive regulation of lipoprotein metabolic process 9.051173e-4
GO:0060696 regulation of phospholipid catabolic process 9.224014e-4
GO:0006285 base-excision repair, AP site formation 9.272464e-4
GO:0032383 regulation of intracellular cholesterol transport 9.456187e-4
GO:0010989 negative regulation of low-density lipoprotein particle clearance 9.456187e-4
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 9.603548e-4
GO:0090085 regulation of protein deubiquitination 9.633807e-4
GO:0018208 peptidyl-proline modification 9.751159e-4
GO:0030221 basophil differentiation 9.868828e-4
GO:0046655 folic acid metabolic process 1.008992e-3
GO:0001941 postsynaptic membrane organization 1.008992e-3
GO:0032862 activation of Rho GTPase activity 1.055001e-3
GO:0035089 establishment of apical/basal cell polarity 1.057544e-3
GO:0046006 regulation of activated T cell proliferation 1.064674e-3
GO:0051443 positive regulation of ubiquitin-protein ligase activity 1.100480e-3
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 1.112536e-3
GO:0002579 positive regulation of antigen processing and presentation 1.118841e-3
GO:0060083 smooth muscle contraction involved in micturition 1.126450e-3
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 1.126450e-3
GO:0000093 mitotic telophase 1.136091e-3
GO:0035095 behavioral response to nicotine 1.146344e-3
GO:0048255 mRNA stabilization 1.163808e-3
GO:0035364 thymine transport 1.201327e-3
GO:0035344 hypoxanthine transport 1.201327e-3
GO:0021528 commissural neuron differentiation in spinal cord 1.201327e-3
GO:0015854 guanine transport 1.201327e-3
GO:0007271 synaptic transmission, cholinergic 1.203884e-3
GO:0007172 signal complex assembly 1.213369e-3
GO:0032312 regulation of ARF GTPase activity 1.216394e-3
GO:0071549 cellular response to dexamethasone stimulus 1.230706e-3
GO:0010742 macrophage derived foam cell differentiation 1.235774e-3
GO:0030574 collagen catabolic process 1.240036e-3
GO:0060219 camera-type eye photoreceptor cell differentiation 1.240802e-3
GO:0042335 cuticle development 1.250634e-3
GO:0010986 positive regulation of lipoprotein particle clearance 1.250634e-3
GO:0032417 positive regulation of sodium:hydrogen antiporter activity 1.299170e-3
GO:0031536 positive regulation of exit from mitosis 1.302259e-3
GO:0043488 regulation of mRNA stability 1.335300e-3
GO:0032423 regulation of mismatch repair 1.366309e-3
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.366309e-3
GO:0007296 vitellogenesis 1.369680e-3
GO:0060713 labyrinthine layer morphogenesis 1.374854e-3
GO:0031284 positive regulation of guanylate cyclase activity 1.379671e-3
GO:0015742 alpha-ketoglutarate transport 1.379671e-3
GO:0031670 cellular response to nutrient 1.385572e-3
GO:0090150 establishment of protein localization in membrane 1.391050e-3
GO:0048733 sebaceous gland development 1.419853e-3
GO:0097107 postsynaptic density assembly 1.420983e-3
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 1.420983e-3
GO:0032786 positive regulation of transcription elongation, DNA-dependent 1.455132e-3
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1.488578e-3
GO:0009817 defense response to fungus, incompatible interaction 1.488578e-3
GO:0010288 response to lead ion 1.497498e-3
GO:0051084 'de novo' posttranslational protein folding 1.529664e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 1.538934e-3
GO:0000216 M/G1 transition of mitotic cell cycle 1.566524e-3
GO:0050881 musculoskeletal movement 1.579101e-3
GO:0033037 polysaccharide localization 1.607822e-3
GO:0032462 regulation of protein homooligomerization 1.668611e-3
GO:0071956 cellular component maintenance at cellular level 1.677313e-3
GO:0003416 endochondral bone growth 1.677313e-3
GO:0030206 chondroitin sulfate biosynthetic process 1.685944e-3
GO:0000413 protein peptidyl-prolyl isomerization 1.687633e-3
GO:0000132 establishment of mitotic spindle orientation 1.733125e-3
GO:0051898 negative regulation of protein kinase B signaling cascade 1.741402e-3
GO:0022616 DNA strand elongation 1.741402e-3
GO:0030007 cellular potassium ion homeostasis 1.757690e-3
GO:0045112 integrin biosynthetic process 1.778952e-3
GO:0006560 proline metabolic process 1.778952e-3
GO:0090130 tissue migration 1.779616e-3
GO:0060253 negative regulation of glial cell proliferation 1.791609e-3
GO:0071731 response to nitric oxide 1.806787e-3
GO:0007184 SMAD protein import into nucleus 1.806787e-3
GO:0070489 T cell aggregation 1.843447e-3
GO:0006356 regulation of transcription from RNA polymerase I promoter 1.880441e-3
GO:0021526 medial motor column neuron differentiation 1.896653e-3
GO:0043306 positive regulation of mast cell degranulation 1.915651e-3
GO:0007044 cell-substrate junction assembly 1.926611e-3
GO:0009253 peptidoglycan catabolic process 1.983988e-3
GO:0061205 paramesonephric duct development 1.983988e-3
GO:0009651 response to salt stress 1.991658e-3
GO:0051580 regulation of neurotransmitter uptake 2.017070e-3
GO:0048752 semicircular canal morphogenesis 2.025566e-3
GO:0010225 response to UV-C 2.050447e-3
GO:0007506 gonadal mesoderm development 2.055436e-3
GO:0016048 detection of temperature stimulus 2.056751e-3
GO:0060169 negative regulation of adenosine receptor signaling pathway 2.077966e-3
GO:0060407 negative regulation of penile erection 2.077966e-3
GO:0002314 germinal center B cell differentiation 2.077966e-3
GO:0046111 xanthine biosynthetic process 2.077966e-3
GO:0046061 dATP catabolic process 2.077966e-3
GO:0006157 deoxyadenosine catabolic process 2.077966e-3
GO:0001829 trophectodermal cell differentiation 2.079424e-3
GO:0060179 male mating behavior 2.090258e-3
GO:2000188 regulation of cholesterol homeostasis 2.090258e-3
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine 2.090258e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 2.168831e-3
GO:0050872 white fat cell differentiation 2.213279e-3
GO:0071299 cellular response to vitamin A 2.246670e-3
GO:0045542 positive regulation of cholesterol biosynthetic process 2.272622e-3
GO:0042267 natural killer cell mediated cytotoxicity 2.276620e-3
GO:0002676 regulation of chronic inflammatory response 2.298351e-3
GO:0016032 viral reproduction 2.366827e-3
GO:0045806 negative regulation of endocytosis 2.369319e-3
GO:0060956 endocardial cell differentiation 2.376495e-3
GO:0061302 smooth muscle cell-matrix adhesion 2.456929e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 2.456929e-3
GO:0046607 positive regulation of centrosome cycle 2.456929e-3
GO:0035845 photoreceptor cell outer segment organization 2.456929e-3
GO:0042994 cytoplasmic sequestering of transcription factor 2.475662e-3
GO:0032464 positive regulation of protein homooligomerization 2.483968e-3
GO:0070309 lens fiber cell morphogenesis 2.523255e-3
GO:0071874 cellular response to norepinephrine stimulus 2.563948e-3
GO:0060084 synaptic transmission involved in micturition 2.563948e-3
GO:0003105 negative regulation of glomerular filtration 2.563948e-3
GO:0070483 detection of hypoxia 2.609357e-3
GO:0019318 hexose metabolic process 2.637861e-3
GO:0009069 serine family amino acid metabolic process 2.638156e-3
GO:0051645 Golgi localization 2.696315e-3
GO:0051365 cellular response to potassium ion starvation 2.696315e-3
GO:0021570 rhombomere 4 development 2.696315e-3
GO:0006097 glyoxylate cycle 2.696315e-3
GO:0030157 pancreatic juice secretion 2.779386e-3
GO:0032319 regulation of Rho GTPase activity 2.792772e-3
GO:0033504 floor plate development 2.801959e-3
GO:0045414 regulation of interleukin-8 biosynthetic process 2.826997e-3
GO:0043467 regulation of generation of precursor metabolites and energy 2.832342e-3
GO:0003420 regulation of growth plate cartilage chondrocyte proliferation 2.885541e-3
GO:0042104 positive regulation of activated T cell proliferation 2.917188e-3
GO:0009304 tRNA transcription 2.945185e-3
GO:0071496 cellular response to external stimulus 2.952094e-3
GO:0072011 glomerular endothelium development 3.069703e-3
GO:0072144 glomerular mesangial cell development 3.069703e-3
GO:0060035 notochord cell development 3.069703e-3
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 3.079672e-3
GO:0015809 arginine transport 3.111939e-3
GO:0032926 negative regulation of activin receptor signaling pathway 3.126813e-3
GO:0060123 regulation of growth hormone secretion 3.139038e-3
GO:0015862 uridine transport 3.142298e-3
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development 3.146351e-3
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 3.152115e-3
GO:0046533 negative regulation of photoreceptor cell differentiation 3.219719e-3
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 3.304449e-3
GO:0016056 rhodopsin mediated signaling pathway 3.310853e-3
GO:0006013 mannose metabolic process 3.391722e-3
GO:0060998 regulation of dendritic spine development 3.410019e-3
GO:0071392 cellular response to estradiol stimulus 3.455444e-3
GO:0042093 T-helper cell differentiation 3.455444e-3
GO:0031297 replication fork processing 3.519029e-3
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 3.519029e-3
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 3.559944e-3
GO:0042271 susceptibility to natural killer cell mediated cytotoxicity 3.598637e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0060192 negative regulation of lipase activity 7.771046e-10
GO:0050995 negative regulation of lipid catabolic process 4.802686e-9
GO:0072109 glomerular mesangium development 7.903130e-9
GO:0033700 phospholipid efflux 1.924874e-8
GO:0072124 regulation of glomerular mesangial cell proliferation 3.350188e-8
GO:0007522 visceral muscle development 4.201374e-8
GO:0051005 negative regulation of lipoprotein lipase activity 5.166701e-8
GO:0034382 chylomicron remnant clearance 5.166701e-8
GO:0031331 positive regulation of cellular catabolic process 5.436244e-8
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 5.495782e-8
GO:0042304 regulation of fatty acid biosynthetic process 7.902019e-8
GO:0071072 negative regulation of phospholipid biosynthetic process 1.070520e-7
GO:0071071 regulation of phospholipid biosynthetic process 1.092978e-7
GO:0009082 branched chain family amino acid biosynthetic process 1.447139e-7
GO:0033344 cholesterol efflux 1.451982e-7
GO:0032365 intracellular lipid transport 1.459824e-7
GO:0043462 regulation of ATPase activity 1.577567e-7
GO:0050994 regulation of lipid catabolic process 1.624089e-7
GO:0046890 regulation of lipid biosynthetic process 1.673787e-7
GO:0045833 negative regulation of lipid metabolic process 2.023181e-7
GO:0090192 regulation of glomerulus development 2.890749e-7
GO:0050779 RNA destabilization 3.130622e-7
GO:0010987 negative regulation of high-density lipoprotein particle clearance 7.817280e-7
GO:0010897 negative regulation of triglyceride catabolic process 7.817280e-7
GO:0048246 macrophage chemotaxis 1.205814e-6
GO:0045862 positive regulation of proteolysis 1.272901e-6
GO:0071316 cellular response to nicotine 1.495216e-6
GO:0002439 chronic inflammatory response to antigenic stimulus 1.495216e-6
GO:0002036 regulation of L-glutamate transport 1.829964e-6
GO:0072044 collecting duct development 1.848326e-6
GO:0032367 intracellular cholesterol transport 1.954666e-6
GO:0051956 negative regulation of amino acid transport 2.453188e-6
GO:0072144 glomerular mesangial cell development 2.576414e-6
GO:0009948 anterior/posterior axis specification 2.622105e-6
GO:0045749 negative regulation of S phase of mitotic cell cycle 2.757814e-6
GO:0030049 muscle filament sliding 3.646989e-6
GO:0048484 enteric nervous system development 3.789361e-6
GO:0060621 negative regulation of cholesterol import 4.282685e-6
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 4.308562e-6
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 4.342638e-6
GO:0003219 cardiac right ventricle formation 4.732655e-6
GO:0032049 cardiolipin biosynthetic process 4.928574e-6
GO:0008595 anterior/posterior axis specification, embryo 5.959820e-6
GO:0031442 positive regulation of mRNA 3'-end processing 7.129187e-6
GO:0072125 negative regulation of glomerular mesangial cell proliferation 7.138254e-6
GO:0003229 ventricular cardiac muscle tissue development 7.322252e-6
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 7.441806e-6
GO:0002268 follicular dendritic cell differentiation 7.554470e-6
GO:0072215 regulation of metanephros development 8.127862e-6
GO:0010985 negative regulation of lipoprotein particle clearance 8.526748e-6
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 8.614014e-6
GO:0031329 regulation of cellular catabolic process 1.017985e-5
GO:0070328 triglyceride homeostasis 1.033972e-5
GO:0090183 regulation of kidney development 1.041919e-5
GO:0007422 peripheral nervous system development 1.050699e-5
GO:0048739 cardiac muscle fiber development 1.109639e-5
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 1.249241e-5
GO:0072110 glomerular mesangial cell proliferation 1.284984e-5
GO:0061046 regulation of branching involved in lung morphogenesis 1.293847e-5
GO:0055010 ventricular cardiac muscle tissue morphogenesis 1.299404e-5
GO:0051055 negative regulation of lipid biosynthetic process 1.339906e-5
GO:0061048 negative regulation of branching involved in lung morphogenesis 1.427714e-5
GO:0045994 positive regulation of translational initiation by iron 1.427714e-5
GO:0034116 positive regulation of heterotypic cell-cell adhesion 1.427714e-5
GO:0002037 negative regulation of L-glutamate transport 1.427714e-5
GO:0035441 cell migration involved in vasculogenesis 1.653044e-5
GO:0007386 compartment pattern specification 1.798941e-5
GO:0045930 negative regulation of mitotic cell cycle 1.828339e-5
GO:0043691 reverse cholesterol transport 1.868286e-5
GO:0045717 negative regulation of fatty acid biosynthetic process 2.062169e-5
GO:0044240 multicellular organismal lipid catabolic process 2.118406e-5
GO:0061014 positive regulation of mRNA catabolic process 2.194521e-5
GO:0060444 branching involved in mammary gland duct morphogenesis 2.251049e-5
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development 2.305876e-5
GO:0072143 mesangial cell development 2.332292e-5
GO:0060033 anatomical structure regression 2.362322e-5
GO:0033085 negative regulation of T cell differentiation in thymus 2.389644e-5
GO:0003002 regionalization 2.414955e-5
GO:0010718 positive regulation of epithelial to mesenchymal transition 2.729086e-5
GO:0048261 negative regulation of receptor-mediated endocytosis 2.817474e-5
GO:0032571 response to vitamin K 3.009323e-5
GO:0090102 cochlea development 3.387804e-5
GO:0060693 regulation of branching involved in salivary gland morphogenesis 3.400589e-5
GO:0071333 cellular response to glucose stimulus 3.421667e-5
GO:0046580 negative regulation of Ras protein signal transduction 3.447172e-5
GO:0001678 cellular glucose homeostasis 3.455592e-5
GO:0003156 regulation of organ formation 3.465490e-5
GO:0033088 negative regulation of immature T cell proliferation in thymus 3.476044e-5
GO:0034447 very-low-density lipoprotein particle clearance 3.504981e-5
GO:0006863 purine base transport 3.708139e-5
GO:0045792 negative regulation of cell size 4.210709e-5
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 4.308299e-5
GO:0006817 phosphate ion transport 4.324865e-5
GO:0000305 response to oxygen radical 4.457983e-5
GO:0065005 protein-lipid complex assembly 4.488445e-5
GO:0014015 positive regulation of gliogenesis 4.595308e-5
GO:0006474 N-terminal protein amino acid acetylation 5.084515e-5
GO:0031440 regulation of mRNA 3'-end processing 5.614496e-5
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 6.266925e-5
GO:0071300 cellular response to retinoic acid 6.418812e-5
GO:0045080 positive regulation of chemokine biosynthetic process 6.425757e-5
GO:0051058 negative regulation of small GTPase mediated signal transduction 6.545441e-5
GO:0010984 regulation of lipoprotein particle clearance 6.696420e-5
GO:0033083 regulation of immature T cell proliferation 6.844657e-5
GO:0071322 cellular response to carbohydrate stimulus 7.033932e-5
GO:0015802 basic amino acid transport 7.110578e-5
GO:0019048 virus-host interaction 7.839204e-5
GO:0060688 regulation of morphogenesis of a branching structure 8.377078e-5
GO:0045618 positive regulation of keratinocyte differentiation 8.537611e-5
GO:0072074 kidney mesenchyme development 8.595409e-5
GO:0072012 glomerulus vasculature development 8.937870e-5
GO:0003205 cardiac chamber development 9.356281e-5
GO:0010717 regulation of epithelial to mesenchymal transition 9.946720e-5
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 1.022955e-4
GO:0071422 succinate transmembrane transport 1.035364e-4
GO:0046889 positive regulation of lipid biosynthetic process 1.040421e-4
GO:0006558 L-phenylalanine metabolic process 1.049157e-4
GO:0045606 positive regulation of epidermal cell differentiation 1.064722e-4
GO:0043653 mitochondrial fragmentation involved in apoptosis 1.080793e-4
GO:0032048 cardiolipin metabolic process 1.082246e-4
GO:0090103 cochlea morphogenesis 1.155013e-4
GO:0003206 cardiac chamber morphogenesis 1.155149e-4
GO:0042267 natural killer cell mediated cytotoxicity 1.164408e-4
GO:0071299 cellular response to vitamin A 1.216585e-4
GO:0060620 regulation of cholesterol import 1.233597e-4
GO:0010823 negative regulation of mitochondrion organization 1.363631e-4
GO:0060026 convergent extension 1.372722e-4
GO:0003209 cardiac atrium morphogenesis 1.396748e-4
GO:0001710 mesodermal cell fate commitment 1.414126e-4
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1.437739e-4
GO:0000271 polysaccharide biosynthetic process 1.451268e-4
GO:0014829 vascular smooth muscle contraction 1.477968e-4
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.485779e-4
GO:0045055 regulated secretory pathway 1.551705e-4
GO:0061013 regulation of mRNA catabolic process 1.557000e-4
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 1.678667e-4
GO:0048332 mesoderm morphogenesis 1.700224e-4
GO:0043587 tongue morphogenesis 1.725758e-4
GO:0045940 positive regulation of steroid metabolic process 1.736608e-4
GO:0071529 cementum mineralization 1.895783e-4
GO:0034369 plasma lipoprotein particle remodeling 1.932198e-4
GO:0009103 lipopolysaccharide biosynthetic process 1.937953e-4
GO:0001885 endothelial cell development 1.976251e-4
GO:0055009 atrial cardiac muscle tissue morphogenesis 1.989601e-4
GO:0014037 Schwann cell differentiation 2.038650e-4
GO:0007501 mesodermal cell fate specification 2.176942e-4
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 2.239215e-4
GO:0002221 pattern recognition receptor signaling pathway 2.315789e-4
GO:0032375 negative regulation of cholesterol transport 2.319231e-4
GO:0072015 glomerular visceral epithelial cell development 2.457769e-4
GO:0006559 L-phenylalanine catabolic process 2.457769e-4
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 2.505626e-4
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.505626e-4
GO:0000185 activation of MAPKKK activity 2.630672e-4
GO:0003231 cardiac ventricle development 2.745925e-4
GO:0014044 Schwann cell development 2.772705e-4
GO:0071803 positive regulation of podosome assembly 3.041861e-4
GO:0030241 skeletal muscle myosin thick filament assembly 3.041861e-4
GO:0042363 fat-soluble vitamin catabolic process 3.041861e-4
GO:0034375 high-density lipoprotein particle remodeling 3.111791e-4
GO:0006656 phosphatidylcholine biosynthetic process 3.119589e-4
GO:0033084 regulation of immature T cell proliferation in thymus 3.139016e-4
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 3.148204e-4
GO:0045922 negative regulation of fatty acid metabolic process 3.149936e-4
GO:0014040 positive regulation of Schwann cell differentiation 3.151271e-4
GO:0006668 sphinganine-1-phosphate metabolic process 3.151271e-4
GO:0033239 negative regulation of cellular amine metabolic process 3.191560e-4
GO:0060696 regulation of phospholipid catabolic process 3.196310e-4
GO:0021515 cell differentiation in spinal cord 3.234564e-4
GO:0003230 cardiac atrium development 3.234564e-4
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 3.358494e-4
GO:0002739 regulation of cytokine secretion involved in immune response 3.380410e-4
GO:0045687 positive regulation of glial cell differentiation 3.525504e-4
GO:0014824 artery smooth muscle contraction 3.538269e-4
GO:0010982 regulation of high-density lipoprotein particle clearance 3.538269e-4
GO:0048012 hepatocyte growth factor receptor signaling pathway 3.547358e-4
GO:0042149 cellular response to glucose starvation 3.560979e-4
GO:0046470 phosphatidylcholine metabolic process 3.570336e-4
GO:0003215 cardiac right ventricle morphogenesis 3.713993e-4
GO:0072017 distal tubule development 3.777078e-4
GO:0030421 defecation 3.820859e-4
GO:0090201 negative regulation of release of cytochrome c from mitochondria 3.857914e-4
GO:0001886 endothelial cell morphogenesis 3.857914e-4
GO:0032148 activation of protein kinase B activity 3.857914e-4
GO:0002227 innate immune response in mucosa 3.884424e-4
GO:0018230 peptidyl-L-cysteine S-palmitoylation 3.976959e-4
GO:0043299 leukocyte degranulation 4.044635e-4
GO:0060744 mammary gland branching involved in thelarche 4.075129e-4
GO:0060070 canonical Wnt receptor signaling pathway 4.115246e-4
GO:0045073 regulation of chemokine biosynthetic process 4.214104e-4
GO:0021904 dorsal/ventral neural tube patterning 4.244712e-4
GO:0060923 cardiac muscle cell fate commitment 4.341732e-4
GO:0043491 protein kinase B signaling cascade 4.468114e-4
GO:0010896 regulation of triglyceride catabolic process 4.485759e-4
GO:0072111 cell proliferation involved in kidney development 4.728143e-4
GO:0003208 cardiac ventricle morphogenesis 4.771270e-4
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 4.810692e-4
GO:0032321 positive regulation of Rho GTPase activity 4.911806e-4
GO:0002740 negative regulation of cytokine secretion involved in immune response 4.997527e-4
GO:0042373 vitamin K metabolic process 5.027465e-4
GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 5.049752e-4
GO:0014807 regulation of somitogenesis 5.049752e-4
GO:0072298 regulation of metanephric glomerulus development 5.158208e-4
GO:0032495 response to muramyl dipeptide 5.162486e-4
GO:0060638 mesenchymal-epithelial cell signaling 5.164347e-4
GO:0006546 glycine catabolic process 5.328019e-4
GO:0009894 regulation of catabolic process 5.428051e-4
GO:0002758 innate immune response-activating signal transduction 5.435241e-4
GO:0006982 response to lipid hydroperoxide 5.620935e-4
GO:0051323 metaphase 5.620935e-4
GO:0006171 cAMP biosynthetic process 5.693588e-4
GO:0051092 positive regulation of NF-kappaB transcription factor activity 5.756904e-4
GO:0010511 regulation of phosphatidylinositol biosynthetic process 6.483792e-4
GO:0015760 glucose-6-phosphate transport 6.483792e-4
GO:0071827 plasma lipoprotein particle organization 6.600891e-4
GO:0001658 branching involved in ureteric bud morphogenesis 6.749905e-4
GO:0072205 metanephric collecting duct development 7.117528e-4
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity 7.298368e-4
GO:0043031 negative regulation of macrophage activation 7.298368e-4
GO:0072278 metanephric comma-shaped body morphogenesis 7.405257e-4
GO:0050935 iridophore differentiation 7.405257e-4
GO:0072284 metanephric S-shaped body morphogenesis 7.405257e-4
GO:0048937 lateral line nerve glial cell development 7.405257e-4
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 7.405257e-4
GO:0009098 leucine biosynthetic process 8.104052e-4
GO:0035674 tricarboxylic acid transmembrane transport 8.104052e-4
GO:0006550 isoleucine catabolic process 8.104052e-4
GO:0032319 regulation of Rho GTPase activity 8.116091e-4
GO:0010900 negative regulation of phosphatidylcholine catabolic process 8.127756e-4
GO:0060675 ureteric bud morphogenesis 8.241127e-4
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 8.323203e-4
GO:0051156 glucose 6-phosphate metabolic process 8.323203e-4
GO:0006867 asparagine transport 8.323203e-4
GO:0001823 mesonephros development 8.415224e-4
GO:0021681 cerebellar granular layer development 8.491736e-4
GO:2000826 regulation of heart morphogenesis 8.647140e-4
GO:2001037 positive regulation of tongue muscle cell differentiation 9.147928e-4
GO:0051639 actin filament network formation 9.147928e-4
GO:0034653 retinoic acid catabolic process 9.147928e-4
GO:0033590 response to cobalamin 9.170496e-4
GO:0045581 negative regulation of T cell differentiation 9.442611e-4
GO:0061136 regulation of proteasomal protein catabolic process 9.503829e-4
GO:0009584 detection of visible light 9.565297e-4
GO:0000089 mitotic metaphase 9.732362e-4
GO:2000194 regulation of female gonad development 9.735108e-4
GO:0061311 cell surface receptor linked signaling pathway involved in heart development 9.808270e-4
GO:2001076 positive regulation of metanephric ureteric bud development 9.848768e-4
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 9.848768e-4
GO:0007356 thorax and anterior abdomen determination 9.848768e-4
GO:0006189 'de novo' IMP biosynthetic process 9.848768e-4
GO:2000027 regulation of organ morphogenesis 9.897511e-4
GO:0015747 urate transport 1.031849e-3
GO:0030300 regulation of intestinal cholesterol absorption 1.040983e-3
GO:0030818 negative regulation of cAMP biosynthetic process 1.045461e-3
GO:0061098 positive regulation of protein tyrosine kinase activity 1.052309e-3
GO:0072179 nephric duct formation 1.062898e-3
GO:0043154 negative regulation of caspase activity 1.131938e-3
GO:0030513 positive regulation of BMP signaling pathway 1.142607e-3
GO:0045103 intermediate filament-based process 1.142607e-3
GO:2000195 negative regulation of female gonad development 1.161841e-3
GO:0045955 negative regulation of calcium ion-dependent exocytosis 1.161841e-3
GO:0050685 positive regulation of mRNA processing 1.179512e-3
GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1.197871e-3
GO:0055090 acylglycerol homeostasis 1.197871e-3
GO:0001667 ameboidal cell migration 1.199600e-3
GO:0044341 sodium-dependent phosphate transport 1.237870e-3
GO:0048706 embryonic skeletal system development 1.238503e-3
GO:0030301 cholesterol transport 1.249639e-3
GO:0034505 tooth mineralization 1.264263e-3
GO:0042593 glucose homeostasis 1.328469e-3
GO:0072126 positive regulation of glomerular mesangial cell proliferation 1.361383e-3
GO:0071506 cellular response to mycophenolic acid 1.361383e-3
GO:0045218 zonula adherens maintenance 1.361383e-3
GO:0050917 sensory perception of umami taste 1.361383e-3
GO:0072011 glomerular endothelium development 1.387850e-3
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 1.387850e-3
GO:0050823 peptide antigen stabilization 1.387850e-3
GO:0045980 negative regulation of nucleotide metabolic process 1.402796e-3
GO:0030509 BMP signaling pathway 1.423881e-3
GO:0019430 removal of superoxide radicals 1.444535e-3
GO:0034101 erythrocyte homeostasis 1.470330e-3
GO:0030198 extracellular matrix organization 1.477598e-3
GO:0010989 negative regulation of low-density lipoprotein particle clearance 1.484627e-3
GO:0002874 regulation of chronic inflammatory response to antigenic stimulus 1.523178e-3
GO:0035645 enteric smooth muscle cell differentiation 1.523178e-3
GO:0007497 posterior midgut development 1.523178e-3
GO:0090184 positive regulation of kidney development 1.532011e-3
GO:0070245 positive regulation of thymocyte apoptosis 1.532011e-3
GO:0010948 negative regulation of cell cycle process 1.571289e-3
GO:0052200 response to host defenses 1.576184e-3
GO:0034372 very-low-density lipoprotein particle remodeling 1.589895e-3
GO:0008203 cholesterol metabolic process 1.623686e-3
GO:0000303 response to superoxide 1.638492e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.651389e-3
GO:0007196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway 1.651389e-3
GO:0048295 positive regulation of isotype switching to IgE isotypes 1.661980e-3
GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure 1.661980e-3
GO:0002275 myeloid cell activation involved in immune response 1.691066e-3
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1.718452e-3
GO:0015851 nucleobase transport 1.721568e-3
GO:0090086 negative regulation of protein deubiquitination 1.722607e-3
GO:0050655 dermatan sulfate proteoglycan metabolic process 1.722607e-3
GO:0009642 response to light intensity 1.722607e-3
GO:0097006 regulation of plasma lipoprotein particle levels 1.741667e-3
GO:0032374 regulation of cholesterol transport 1.741837e-3
GO:0070243 regulation of thymocyte apoptosis 1.748341e-3
GO:0070234 positive regulation of T cell apoptosis 1.750080e-3
GO:0001570 vasculogenesis 1.751433e-3
GO:0035372 protein localization to microtubule 1.785446e-3
GO:0007140 male meiosis 1.829635e-3
GO:0048754 branching morphogenesis of a tube 1.842020e-3
GO:0006572 tyrosine catabolic process 1.851328e-3
GO:0090218 positive regulation of lipid kinase activity 1.875351e-3
GO:0001829 trophectodermal cell differentiation 1.926751e-3
GO:0060065 uterus development 1.991700e-3
GO:0016125 sterol metabolic process 2.053412e-3
GO:0046849 bone remodeling 2.074883e-3
GO:2000573 positive regulation of DNA biosynthetic process 2.139649e-3
GO:0045662 negative regulation of myoblast differentiation 2.145039e-3
GO:0033692 cellular polysaccharide biosynthetic process 2.192490e-3
GO:0045921 positive regulation of exocytosis 2.194994e-3
GO:0003222 ventricular trabecular myocardium morphogenesis 2.210436e-3
GO:0031536 positive regulation of exit from mitosis 2.246771e-3
GO:0007354 zygotic determination of anterior/posterior axis, embryo 2.261133e-3
GO:0007440 foregut morphogenesis 2.263090e-3
GO:0045723 positive regulation of fatty acid biosynthetic process 2.278726e-3
GO:0001755 neural crest cell migration 2.328639e-3
GO:0044058 regulation of digestive system process 2.339373e-3
GO:0072203 cell proliferation involved in metanephros development 2.359799e-3
GO:0010656 negative regulation of muscle cell apoptosis 2.365962e-3
GO:0034370 triglyceride-rich lipoprotein particle remodeling 2.366046e-3
GO:0046039 GTP metabolic process 2.385586e-3
GO:0071257 cellular response to electrical stimulus 2.388190e-3
GO:0045104 intermediate filament cytoskeleton organization 2.395717e-3
GO:0032488 Cdc42 protein signal transduction 2.409389e-3
GO:0032862 activation of Rho GTPase activity 2.481274e-3
GO:0000578 embryonic axis specification 2.494244e-3
GO:0045834 positive regulation of lipid metabolic process 2.531171e-3
GO:0045684 positive regulation of epidermis development 2.543602e-3
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 2.552004e-3
GO:0031581 hemidesmosome assembly 2.557359e-3
GO:0022011 myelination in peripheral nervous system 2.557359e-3
GO:0072498 embryonic skeletal joint development 2.571930e-3
GO:0006405 RNA export from nucleus 2.572152e-3
GO:0000060 protein import into nucleus, translocation 2.572152e-3
GO:0061077 chaperone-mediated protein folding 2.577245e-3
GO:0015809 arginine transport 2.607096e-3
GO:0060981 cell migration involved in coronary angiogenesis 2.625565e-3
GO:0071670 smooth muscle cell chemotaxis 2.625565e-3
GO:0051725 protein de-ADP-ribosylation 2.625565e-3
GO:0002224 toll-like receptor signaling pathway 2.671864e-3
GO:0072112 glomerular visceral epithelial cell differentiation 2.684646e-3
GO:0006927 transformed cell apoptosis 2.712799e-3
GO:0042274 ribosomal small subunit biogenesis 2.719687e-3
GO:0048298 positive regulation of isotype switching to IgA isotypes 2.762418e-3
GO:0046487 glyoxylate metabolic process 2.794999e-3
GO:0032682 negative regulation of chemokine production 2.794999e-3
GO:0009896 positive regulation of catabolic process 2.804289e-3
GO:0042415 norepinephrine metabolic process 2.834285e-3
GO:0090209 negative regulation of triglyceride metabolic process 2.892053e-3
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 2.942967e-3
GO:0010159 specification of organ position 2.942967e-3
GO:0032012 regulation of ARF protein signal transduction 2.957921e-3
GO:0007141 male meiosis I 2.959312e-3
GO:0010288 response to lead ion 2.973776e-3
GO:0035520 monoubiquitinated protein deubiquitination 2.988565e-3
GO:0071460 cellular response to cell-matrix adhesion 2.988565e-3
GO:0006669 sphinganine-1-phosphate biosynthetic process 2.988565e-3
GO:0060160 negative regulation of dopamine receptor signaling pathway 2.990217e-3
GO:0070845 polyubiquitinated misfolded protein transport 2.990217e-3
GO:0050651 dermatan sulfate proteoglycan biosynthetic process 2.990217e-3
GO:0015746 citrate transport 2.990217e-3
GO:0009817 defense response to fungus, incompatible interaction 2.990217e-3
GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing 2.990217e-3
GO:0033591 response to L-ascorbic acid 3.022280e-3
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 3.024151e-3
GO:0045945 positive regulation of transcription from RNA polymerase III promoter 3.028531e-3
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 3.048548e-3
GO:0030218 erythrocyte differentiation 3.095186e-3
GO:0001707 mesoderm formation 3.098984e-3
GO:0035306 positive regulation of dephosphorylation 3.102564e-3
GO:0021871 forebrain regionalization 3.148087e-3
GO:0060272 embryonic skeletal joint morphogenesis 3.148962e-3
GO:0009952 anterior/posterior pattern specification 3.168810e-3
GO:0034442 regulation of lipoprotein oxidation 3.298127e-3
GO:0072006 nephron development 3.354398e-3
GO:0042703 menstruation 3.365060e-3
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 3.365060e-3
GO:0019101 female somatic sex determination 3.365060e-3
GO:0060299 negative regulation of sarcomere organization 3.365060e-3
GO:0001579 medium-chain fatty acid transport 3.365060e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 3.365060e-3
GO:0002756 MyD88-independent toll-like receptor signaling pathway 3.365060e-3
GO:0006285 base-excision repair, AP site formation 3.365060e-3
GO:0043586 tongue development 3.397181e-3
GO:0030865 cortical cytoskeleton organization 3.469275e-3
GO:0060037 pharyngeal system development 3.472475e-3
GO:0046855 inositol phosphate dephosphorylation 3.483934e-3
GO:0072178 nephric duct morphogenesis 3.507972e-3
GO:0021520 spinal cord motor neuron cell fate specification 3.507972e-3
GO:0060686 negative regulation of prostatic bud formation 3.629638e-3
GO:0050908 detection of light stimulus involved in visual perception 3.629638e-3
GO:0050748 negative regulation of lipoprotein metabolic process 3.636766e-3
GO:0071044 histone mRNA catabolic process 3.671855e-3
GO:0010893 positive regulation of steroid biosynthetic process 3.699339e-3
GO:0030219 megakaryocyte differentiation 3.763582e-3
GO:0061138 morphogenesis of a branching epithelium 3.812144e-3
GO:0016032 viral reproduction 3.927503e-3
GO:0006415 translational termination 3.947202e-3
GO:0045541 negative regulation of cholesterol biosynthetic process 3.962033e-3
GO:0002115 store-operated calcium entry 3.962033e-3
GO:0035307 positive regulation of protein dephosphorylation 4.001367e-3
GO:0060685 regulation of prostatic bud formation 4.020744e-3
GO:0051450 myoblast proliferation 4.020744e-3
GO:0007498 mesoderm development 4.052281e-3
GO:0009895 negative regulation of catabolic process 4.053470e-3
GO:0001763 morphogenesis of a branching structure 4.063056e-3
GO:0048793 pronephros development 4.063395e-3
GO:0045620 negative regulation of lymphocyte differentiation 4.074561e-3
GO:0031034 myosin filament assembly 4.088620e-3
GO:0007216 metabotropic glutamate receptor signaling pathway 4.114340e-3
GO:0051148 negative regulation of muscle cell differentiation 4.383614e-3
GO:0051588 regulation of neurotransmitter transport 4.435470e-3
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 4.450080e-3
GO:0060485 mesenchyme development 4.470422e-3
GO:0061097 regulation of protein tyrosine kinase activity 4.479915e-3
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 4.480598e-3
GO:0002385 mucosal immune response 4.494794e-3
GO:0060029 convergent extension involved in organogenesis 4.576706e-3
GO:0018106 peptidyl-histidine phosphorylation 4.610742e-3
GO:0003266 regulation of secondary heart field cardioblast proliferation 4.644568e-3
GO:0015914 phospholipid transport 4.660291e-3
GO:0031639 plasminogen activation 4.749820e-3
GO:0006297 nucleotide-excision repair, DNA gap filling 4.749820e-3
GO:0006603 phosphocreatine metabolic process 4.749820e-3
GO:0060710 chorio-allantoic fusion 4.847111e-3
GO:0007044 cell-substrate junction assembly 4.847710e-3
GO:0072050 S-shaped body morphogenesis 4.855479e-3
GO:0060707 trophoblast giant cell differentiation 4.855479e-3
GO:0072049 comma-shaped body morphogenesis 4.855479e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 4.864934e-3
GO:0019853 L-ascorbic acid biosynthetic process 4.896762e-3
GO:0061049 cell growth involved in cardiac muscle cell development 4.937499e-3
GO:0072255 metanephric glomerular mesangial cell development 4.937499e-3
GO:0045064 T-helper 2 cell differentiation 4.937499e-3
GO:0072264 metanephric glomerular endothelium development 4.937499e-3
GO:0003331 positive regulation of extracellular matrix constituent secretion 4.937499e-3
GO:0003104 positive regulation of glomerular filtration 4.937499e-3
GO:0038001 paracrine signaling 4.937499e-3
GO:0008065 establishment of blood-nerve barrier 4.937499e-3
GO:0014873 response to muscle activity involved in regulation of muscle adaptation 4.937499e-3
GO:0009190 cyclic nucleotide biosynthetic process 4.997507e-3
GO:0000460 maturation of 5.8S rRNA 5.004257e-3
GO:0033147 negative regulation of estrogen receptor signaling pathway 5.012188e-3
GO:0019049 evasion of host defenses by virus 5.012188e-3
GO:0034377 plasma lipoprotein particle assembly 5.042756e-3
GO:0060976 coronary vasculature development 5.065245e-3
GO:0021978 telencephalon regionalization 5.114157e-3
GO:0010872 regulation of cholesterol esterification 5.126734e-3
GO:0072075 metanephric mesenchyme development 5.136115e-3
GO:0072198 mesenchymal cell proliferation involved in ureter development 5.138324e-3
GO:0072101 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway 5.138324e-3
GO:0072200 negative regulation of mesenchymal cell proliferation involved in ureter development 5.138324e-3
GO:0072138 mesenchymal cell proliferation involved in ureteric bud development 5.138324e-3
GO:0072192 ureter epithelial cell differentiation 5.138324e-3
GO:2000007 negative regulation of metanephric comma-shaped body morphogenesis 5.138324e-3
GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis 5.138324e-3
GO:2000005 negative regulation of metanephric S-shaped body morphogenesis 5.138324e-3
GO:0090194 negative regulation of glomerulus development 5.138324e-3
GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis 5.138324e-3
GO:0061151 BMP signaling pathway involved in renal system segmentation 5.138324e-3
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 5.138324e-3
GO:0048392 intermediate mesodermal cell differentiation 5.138324e-3
GO:0007500 mesodermal cell fate determination 5.138324e-3
GO:0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway 5.138324e-3
GO:0060502 epithelial cell proliferation involved in lung morphogenesis 5.138324e-3
GO:0055020 positive regulation of cardiac muscle fiber development 5.138324e-3
GO:0071893 BMP signaling pathway involved in nephric duct formation 5.138324e-3
GO:0061149 BMP signaling pathway involved in ureter morphogenesis 5.138324e-3
GO:0061155 pulmonary artery endothelial tube morphogenesis 5.138324e-3
GO:0060503 bud dilation involved in lung branching 5.138324e-3
GO:0090193 positive regulation of glomerulus development 5.317650e-3
GO:0048568 embryonic organ development 5.335610e-3
GO:0032472 Golgi calcium ion transport 5.335933e-3
GO:0032468 Golgi calcium ion homeostasis 5.335933e-3
GO:0042789 mRNA transcription from RNA polymerase II promoter 5.335933e-3
GO:0031296 B cell costimulation 5.335933e-3
GO:0030026 cellular manganese ion homeostasis 5.335933e-3
GO:0034381 plasma lipoprotein particle clearance 5.340879e-3
GO:0033081 regulation of T cell differentiation in thymus 5.376337e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 5.452581e-3
GO:0048340 paraxial mesoderm morphogenesis 5.452581e-3
GO:0006184 GTP catabolic process 5.490093e-3
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 5.502482e-3
GO:0035304 regulation of protein dephosphorylation 5.514710e-3
GO:0007614 short-term memory 5.514886e-3
GO:0006406 mRNA export from nucleus 5.529917e-3
GO:0048251 elastic fiber assembly 5.535906e-3
GO:0072199 regulation of mesenchymal cell proliferation involved in ureter development 5.536575e-3
GO:0071294 cellular response to zinc ion 5.536575e-3