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Novel motif:20

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name:motif20_TGNAGC

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0007522 visceral muscle development 2.217658e-13
GO:0051293 establishment of spindle localization 2.222387e-10
GO:0006821 chloride transport 3.427042e-10
GO:0010984 regulation of lipoprotein particle clearance 6.976882e-10
GO:0055009 atrial cardiac muscle tissue morphogenesis 9.283898e-10
GO:0015698 inorganic anion transport 4.779103e-9
GO:0009303 rRNA transcription 5.166038e-9
GO:0000132 establishment of mitotic spindle orientation 1.028727e-8
GO:0007288 sperm axoneme assembly 5.231357e-8
GO:0007509 mesoderm migration involved in gastrulation 6.524924e-8
GO:0010988 regulation of low-density lipoprotein particle clearance 1.040160e-7
GO:0040001 establishment of mitotic spindle localization 1.580599e-7
GO:0010985 negative regulation of lipoprotein particle clearance 2.123437e-7
GO:0008078 mesodermal cell migration 2.191570e-7
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 3.602981e-7
GO:0030010 establishment of cell polarity 5.516614e-7
GO:0051298 centrosome duplication 5.671503e-7
GO:0046314 phosphocreatine biosynthetic process 9.156936e-7
GO:0043171 peptide catabolic process 1.240731e-6
GO:0042396 phosphagen biosynthetic process 1.393668e-6
GO:0032796 uropod organization 1.655236e-6
GO:0090224 regulation of spindle organization 1.794273e-6
GO:0031333 negative regulation of protein complex assembly 1.983469e-6
GO:0006820 anion transport 2.516200e-6
GO:0060346 bone trabecula formation 2.786524e-6
GO:0035082 axoneme assembly 3.346192e-6
GO:0051005 negative regulation of lipoprotein lipase activity 3.377828e-6
GO:0010987 negative regulation of high-density lipoprotein particle clearance 3.645765e-6
GO:0010897 negative regulation of triglyceride catabolic process 3.645765e-6
GO:0045218 zonula adherens maintenance 4.048869e-6
GO:0010982 regulation of high-density lipoprotein particle clearance 5.080215e-6
GO:0030837 negative regulation of actin filament polymerization 5.220233e-6
GO:0003230 cardiac atrium development 5.410961e-6
GO:0002002 regulation of angiotensin levels in blood 5.826168e-6
GO:0043462 regulation of ATPase activity 6.236479e-6
GO:0090136 epithelial cell-cell adhesion 6.392828e-6
GO:0001574 ganglioside biosynthetic process 6.475645e-6
GO:0006853 carnitine shuttle 6.668381e-6
GO:0009304 tRNA transcription 6.836778e-6
GO:0046627 negative regulation of insulin receptor signaling pathway 8.511274e-6
GO:0010989 negative regulation of low-density lipoprotein particle clearance 8.733303e-6
GO:0003209 cardiac atrium morphogenesis 9.462729e-6
GO:0051591 response to cAMP 1.003245e-5
GO:0001768 establishment of T cell polarity 1.035389e-5
GO:0001661 conditioned taste aversion 1.035532e-5
GO:0006884 cell volume homeostasis 1.075088e-5
GO:0021554 optic nerve development 1.295315e-5
GO:0007398 ectoderm development 1.585554e-5
GO:2000119 negative regulation of sodium-dependent phosphate transport 1.834582e-5
GO:0010388 cullin deneddylation 2.013486e-5
GO:0006600 creatine metabolic process 2.525979e-5
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 2.547548e-5
GO:0042304 regulation of fatty acid biosynthetic process 2.568129e-5
GO:0085029 extracellular matrix assembly 2.720214e-5
GO:0070943 neutrophil mediated killing of symbiont cell 2.760759e-5
GO:0010896 regulation of triglyceride catabolic process 2.900030e-5
GO:0048251 elastic fiber assembly 3.065490e-5
GO:0060337 type I interferon-mediated signaling pathway 3.129624e-5
GO:0045933 positive regulation of muscle contraction 3.322391e-5
GO:0006740 NADPH regeneration 3.337762e-5
GO:0032272 negative regulation of protein polymerization 3.477288e-5
GO:0090140 regulation of mitochondrial fission 4.280339e-5
GO:0051546 keratinocyte migration 4.356564e-5
GO:0019884 antigen processing and presentation of exogenous antigen 4.380820e-5
GO:0032571 response to vitamin K 4.507905e-5
GO:0007163 establishment or maintenance of cell polarity 5.296041e-5
GO:0000212 meiotic spindle organization 5.335676e-5
GO:0006384 transcription initiation from RNA polymerase III promoter 5.551395e-5
GO:0010815 bradykinin catabolic process 5.629881e-5
GO:0042733 embryonic digit morphogenesis 5.714405e-5
GO:0035601 protein deacylation 5.888660e-5
GO:0006476 protein deacetylation 6.253463e-5
GO:0015858 nucleoside transport 6.298028e-5
GO:0070933 histone H4 deacetylation 6.691678e-5
GO:0090102 cochlea development 6.811570e-5
GO:0034340 response to type I interferon 6.962962e-5
GO:2000171 negative regulation of dendrite development 7.239058e-5
GO:0008210 estrogen metabolic process 7.248196e-5
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 7.287692e-5
GO:0035814 negative regulation of renal sodium excretion 7.432434e-5
GO:0021562 vestibulocochlear nerve development 7.519241e-5
GO:0060338 regulation of type I interferon-mediated signaling pathway 7.896674e-5
GO:0021631 optic nerve morphogenesis 8.492207e-5
GO:0071585 detoxification of cadmium ion 8.723849e-5
GO:0035691 macrophage migration inhibitory factor signaling pathway 8.858458e-5
GO:0016575 histone deacetylation 8.895447e-5
GO:0072162 metanephric mesenchymal cell differentiation 8.996213e-5
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 9.719035e-5
GO:0030835 negative regulation of actin filament depolymerization 9.782061e-5
GO:0071732 cellular response to nitric oxide 1.009741e-4
GO:0051693 actin filament capping 1.056122e-4
GO:0034969 histone arginine methylation 1.133277e-4
GO:0060644 mammary gland epithelial cell differentiation 1.155552e-4
GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.194311e-4
GO:0034330 cell junction organization 1.196409e-4
GO:0019693 ribose phosphate metabolic process 1.271754e-4
GO:0035067 negative regulation of histone acetylation 1.275324e-4
GO:0071584 negative regulation of zinc ion import 1.417975e-4
GO:0090281 negative regulation of calcium ion import 1.417975e-4
GO:0071731 response to nitric oxide 1.434445e-4
GO:0018345 protein palmitoylation 1.475361e-4
GO:0009109 coenzyme catabolic process 1.478551e-4
GO:0072277 metanephric glomerular capillary formation 1.630230e-4
GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 1.695315e-4
GO:0021819 layer formation in cerebral cortex 1.845615e-4
GO:0060977 coronary vasculature morphogenesis 1.860216e-4
GO:0048711 positive regulation of astrocyte differentiation 1.971436e-4
GO:0006099 tricarboxylic acid cycle 1.972600e-4
GO:0009052 pentose-phosphate shunt, non-oxidative branch 1.981626e-4
GO:0035089 establishment of apical/basal cell polarity 2.007855e-4
GO:0006098 pentose-phosphate shunt 2.008705e-4
GO:0033590 response to cobalamin 2.053697e-4
GO:0006117 acetaldehyde metabolic process 2.053697e-4
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 2.127182e-4
GO:0035909 aorta morphogenesis 2.181893e-4
GO:0042797 tRNA transcription from RNA polymerase III promoter 2.186140e-4
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 2.186140e-4
GO:0018200 peptidyl-glutamic acid modification 2.188394e-4
GO:0051295 establishment of meiotic spindle localization 2.237181e-4
GO:0046487 glyoxylate metabolic process 2.415379e-4
GO:0019320 hexose catabolic process 2.431321e-4
GO:0060253 negative regulation of glial cell proliferation 2.680873e-4
GO:0070932 histone H3 deacetylation 2.739880e-4
GO:0045687 positive regulation of glial cell differentiation 2.881286e-4
GO:0018022 peptidyl-lysine methylation 2.954670e-4
GO:0002026 regulation of the force of heart contraction 2.957913e-4
GO:0006471 protein ADP-ribosylation 3.005109e-4
GO:0045217 cell-cell junction maintenance 3.062420e-4
GO:0048841 regulation of axon extension involved in axon guidance 3.063154e-4
GO:0006007 glucose catabolic process 3.066761e-4
GO:0046356 acetyl-CoA catabolic process 3.101315e-4
GO:0007132 meiotic metaphase I 3.145729e-4
GO:0090169 regulation of spindle assembly 3.155652e-4
GO:0090234 regulation of kinetochore assembly 3.155652e-4
GO:0019532 oxalate transport 3.245619e-4
GO:0060191 regulation of lipase activity 3.447850e-4
GO:0043299 leukocyte degranulation 3.560468e-4
GO:0051323 metaphase 3.592927e-4
GO:0046164 alcohol catabolic process 3.595936e-4
GO:0017187 peptidyl-glutamic acid carboxylation 3.675058e-4
GO:0045955 negative regulation of calcium ion-dependent exocytosis 3.677396e-4
GO:0001573 ganglioside metabolic process 3.808656e-4
GO:0060192 negative regulation of lipase activity 4.121539e-4
GO:0051660 establishment of centrosome localization 4.340102e-4
GO:0021540 corpus callosum morphogenesis 4.340102e-4
GO:0006760 folic acid-containing compound metabolic process 4.369167e-4
GO:0046365 monosaccharide catabolic process 4.439524e-4
GO:0071956 cellular component maintenance at cellular level 4.461276e-4
GO:0006110 regulation of glycolysis 4.603538e-4
GO:0060696 regulation of phospholipid catabolic process 4.765148e-4
GO:0000226 microtubule cytoskeleton organization 4.992560e-4
GO:0019321 pentose metabolic process 5.050765e-4
GO:0009060 aerobic respiration 5.198540e-4
GO:0034505 tooth mineralization 5.205097e-4
GO:2000974 negative regulation of pro-B cell differentiation 5.221184e-4
GO:0002906 negative regulation of mature B cell apoptosis 5.221184e-4
GO:0021801 cerebral cortex radial glia guided migration 5.306691e-4
GO:0061054 dermatome development 5.410696e-4
GO:0051835 positive regulation of synapse structural plasticity 5.410696e-4
GO:0043163 cell envelope organization 5.410696e-4
GO:0051645 Golgi localization 5.410696e-4
GO:0031658 negative regulation of cyclin-dependent protein kinase activity involved in G1/S 5.543001e-4
GO:0007092 activation of mitotic anaphase-promoting complex activity 5.543001e-4
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 5.679457e-4
GO:0097107 postsynaptic density assembly 5.679457e-4
GO:0034766 negative regulation of ion transmembrane transport 5.679457e-4
GO:0072164 mesonephric tubule development 5.790250e-4
GO:0030237 female sex determination 6.223818e-4
GO:0010455 positive regulation of cell fate commitment 6.346458e-4
GO:0043985 histone H4-R3 methylation 6.379263e-4
GO:0090209 negative regulation of triglyceride metabolic process 6.619544e-4
GO:0060976 coronary vasculature development 6.798421e-4
GO:0090141 positive regulation of mitochondrial fission 6.829059e-4
GO:0031936 negative regulation of chromatin silencing 7.119273e-4
GO:0035247 peptidyl-arginine omega-N-methylation 7.122353e-4
GO:0048627 myoblast development 7.151931e-4
GO:0001578 microtubule bundle formation 7.252416e-4
GO:0070509 calcium ion import 7.352796e-4
GO:0042447 hormone catabolic process 7.368332e-4
GO:0007051 spindle organization 7.441548e-4
GO:0007016 cytoskeletal anchoring at plasma membrane 7.477673e-4
GO:0018095 protein polyglutamylation 7.560660e-4
GO:2000786 positive regulation of autophagic vacuole assembly 7.728647e-4
GO:0030488 tRNA methylation 7.728647e-4
GO:0051494 negative regulation of cytoskeleton organization 7.945936e-4
GO:0014015 positive regulation of gliogenesis 8.077092e-4
GO:0010517 regulation of phospholipase activity 8.087009e-4
GO:0071280 cellular response to copper ion 8.256340e-4
GO:0016241 regulation of macroautophagy 8.256340e-4
GO:0045717 negative regulation of fatty acid biosynthetic process 8.467577e-4
GO:0042483 negative regulation of odontogenesis 8.509266e-4
GO:0000302 response to reactive oxygen species 8.653406e-4
GO:0010536 positive regulation of activation of Janus kinase activity 8.741305e-4
GO:0090162 establishment of epithelial cell polarity 8.788862e-4
GO:0032862 activation of Rho GTPase activity 8.907687e-4
GO:0014040 positive regulation of Schwann cell differentiation 9.222215e-4
GO:0035105 sterol regulatory element binding protein import into nucleus 9.307784e-4
GO:0070947 neutrophil mediated killing of fungus 9.320833e-4
GO:0006684 sphingomyelin metabolic process 9.596182e-4
GO:0032365 intracellular lipid transport 9.664310e-4
GO:0090130 tissue migration 9.702405e-4
GO:0051187 cofactor catabolic process 9.834193e-4
GO:0045061 thymic T cell selection 9.953545e-4
GO:0072668 tubulin complex biogenesis 1.012363e-3
GO:0022007 convergent extension involved in neural plate elongation 1.051417e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.052834e-3
GO:0070734 histone H3-K27 methylation 1.066626e-3
GO:0090149 membrane fission involved in mitochondrial fission 1.095922e-3
GO:0003374 dynamin polymerization involved in mitochondrial fission 1.095922e-3
GO:0072239 metanephric glomerulus vasculature development 1.098806e-3
GO:0006739 NADP metabolic process 1.140161e-3
GO:0033326 cerebrospinal fluid secretion 1.163971e-3
GO:0014807 regulation of somitogenesis 1.176918e-3
GO:0005997 xylulose metabolic process 1.176918e-3
GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development 1.191310e-3
GO:0007202 activation of phospholipase C activity 1.224069e-3
GO:0030953 astral microtubule organization 1.231792e-3
GO:0030834 regulation of actin filament depolymerization 1.232186e-3
GO:0001885 endothelial cell development 1.246971e-3
GO:0042472 inner ear morphogenesis 1.302119e-3
GO:0001553 luteinization 1.302628e-3
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 1.309151e-3
GO:0007512 adult heart development 1.336396e-3
GO:0090342 regulation of cell aging 1.366542e-3
GO:0034983 peptidyl-lysine deacetylation 1.376327e-3
GO:0035313 wound healing, spreading of epidermal cells 1.407313e-3
GO:0051081 nuclear envelope disassembly 1.409782e-3
GO:0045794 negative regulation of cell volume 1.420792e-3
GO:0006551 leucine metabolic process 1.441903e-3
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 1.507182e-3
GO:0061032 visceral serous pericardium development 1.507182e-3
GO:0043471 regulation of cellular carbohydrate catabolic process 1.555412e-3
GO:0060236 regulation of mitotic spindle organization 1.607471e-3
GO:0002830 positive regulation of type 2 immune response 1.659691e-3
GO:0031343 positive regulation of cell killing 1.683129e-3
GO:0010821 regulation of mitochondrion organization 1.711272e-3
GO:0045989 positive regulation of striated muscle contraction 1.732521e-3
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 1.738253e-3
GO:0090307 spindle assembly involved in mitosis 1.792903e-3
GO:0060290 transdifferentiation 1.792903e-3
GO:0046884 follicle-stimulating hormone secretion 1.818829e-3
GO:0032275 luteinizing hormone secretion 1.818829e-3
GO:0046373 L-arabinose metabolic process 1.943042e-3
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 1.951426e-3
GO:0006636 unsaturated fatty acid biosynthetic process 1.957868e-3
GO:0002523 leukocyte migration involved in inflammatory response 2.011853e-3
GO:0060343 trabecula formation 2.013431e-3
GO:0043244 regulation of protein complex disassembly 2.031720e-3
GO:0007000 nucleolus organization 2.037051e-3
GO:0031064 negative regulation of histone deacetylation 2.091493e-3
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 2.110499e-3
GO:0046173 polyol biosynthetic process 2.120099e-3
GO:0032613 interleukin-10 production 2.120099e-3
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 2.128222e-3
GO:0045060 negative thymic T cell selection 2.173172e-3
GO:0035269 protein O-linked mannosylation 2.249901e-3
GO:0071300 cellular response to retinoic acid 2.251670e-3
GO:0006081 cellular aldehyde metabolic process 2.276173e-3
GO:0060363 cranial suture morphogenesis 2.283816e-3
GO:0015840 urea transport 2.306761e-3
GO:0060923 cardiac muscle cell fate commitment 2.324912e-3
GO:0032463 negative regulation of protein homooligomerization 2.366868e-3
GO:0048839 inner ear development 2.385065e-3
GO:0003416 endochondral bone growth 2.386579e-3
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 2.407302e-3
GO:0060262 negative regulation of N-terminal protein palmitoylation 2.436733e-3
GO:0090241 negative regulation of histone H4 acetylation 2.463886e-3
GO:0071392 cellular response to estradiol stimulus 2.467249e-3
GO:0006105 succinate metabolic process 2.477895e-3
GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway 2.501004e-3
GO:0034637 cellular carbohydrate biosynthetic process 2.530218e-3
GO:0044088 regulation of vacuole organization 2.564154e-3
GO:2001037 positive regulation of tongue muscle cell differentiation 2.580089e-3
GO:0097152 mesenchymal cell apoptosis 2.580089e-3
GO:0002438 acute inflammatory response to antigenic stimulus 2.580089e-3
GO:0060982 coronary artery morphogenesis 2.580089e-3
GO:0042335 cuticle development 2.580089e-3
GO:0018027 peptidyl-lysine dimethylation 2.625623e-3
GO:0021602 cranial nerve morphogenesis 2.691666e-3
GO:0042471 ear morphogenesis 2.710441e-3
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 2.716154e-3
GO:0050902 leukocyte adhesive activation 2.716154e-3
GO:0003166 bundle of His development 2.741032e-3
GO:0070574 cadmium ion transmembrane transport 2.749051e-3
GO:0045606 positive regulation of epidermal cell differentiation 2.799274e-3
GO:0046165 alcohol biosynthetic process 2.838855e-3
GO:0060969 negative regulation of gene silencing 2.879028e-3
GO:0048842 positive regulation of axon extension involved in axon guidance 2.883961e-3
GO:0010518 positive regulation of phospholipase activity 2.948271e-3
GO:0000086 G2/M transition of mitotic cell cycle 2.964113e-3
GO:0045684 positive regulation of epidermis development 2.989546e-3
GO:0014874 response to stimulus involved in regulation of muscle adaptation 3.001766e-3
GO:0006306 DNA methylation 3.013807e-3
GO:0018026 peptidyl-lysine monomethylation 3.043505e-3
GO:0007021 tubulin complex assembly 3.053743e-3
GO:0045446 endothelial cell differentiation 3.101739e-3
GO:0044319 wound healing, spreading of cells 3.157898e-3
GO:0019883 antigen processing and presentation of endogenous antigen 3.161179e-3
GO:0048227 plasma membrane to endosome transport 3.164424e-3
GO:0048664 neuron fate determination 3.180729e-3
GO:0048705 skeletal system morphogenesis 3.181518e-3
GO:0045987 positive regulation of smooth muscle contraction 3.209434e-3
GO:0043001 Golgi to plasma membrane protein transport 3.286744e-3
GO:0060452 positive regulation of cardiac muscle contraction 3.381186e-3
GO:0072166 posterior mesonephric tubule development 3.395756e-3
GO:0042074 cell migration involved in gastrulation 3.447648e-3
GO:0010863 positive regulation of phospholipase C activity 3.475812e-3
GO:0015879 carnitine transport 3.480077e-3
GO:0031935 regulation of chromatin silencing 3.502322e-3
GO:0034111 negative regulation of homotypic cell-cell adhesion 3.566919e-3
GO:0060981 cell migration involved in coronary angiogenesis 3.567699e-3
GO:0071670 smooth muscle cell chemotaxis 3.567699e-3
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 3.588686e-3
GO:0033559 unsaturated fatty acid metabolic process 3.596049e-3
GO:0060251 regulation of glial cell proliferation 3.613854e-3
GO:0060193 positive regulation of lipase activity 3.637283e-3
GO:0060712 spongiotrophoblast layer development 3.646729e-3
GO:0010544 negative regulation of platelet activation 3.683988e-3
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 3.718633e-3
GO:0042756 drinking behavior 3.734492e-3
GO:0006633 fatty acid biosynthetic process 3.807202e-3
GO:0006094 gluconeogenesis 3.810582e-3
GO:0021799 cerebral cortex radially oriented cell migration 3.811623e-3
GO:0006497 protein lipidation 3.816897e-3
GO:2000737 negative regulation of stem cell differentiation 3.856264e-3
GO:0060348 bone development 3.871059e-3
GO:0045023 G0 to G1 transition 3.907030e-3
GO:0002005 angiotensin catabolic process in blood 3.907030e-3
GO:0045879 negative regulation of smoothened signaling pathway 3.949854e-3
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 3.956912e-3
GO:0045922 negative regulation of fatty acid metabolic process 3.962738e-3
GO:0050769 positive regulation of neurogenesis 3.981727e-3
GO:0048672 positive regulation of collateral sprouting 4.059552e-3
GO:0048680 positive regulation of axon regeneration 4.059552e-3
GO:0002579 positive regulation of antigen processing and presentation 4.078231e-3
GO:0007098 centrosome cycle 4.089418e-3
GO:0033238 regulation of cellular amine metabolic process 4.176066e-3
GO:0002635 negative regulation of germinal center formation 4.201701e-3
GO:0035802 adrenal cortex formation 4.223447e-3
GO:0001510 RNA methylation 4.233258e-3
GO:0031284 positive regulation of guanylate cyclase activity 4.243127e-3
GO:0071674 mononuclear cell migration 4.243127e-3
GO:0045645 positive regulation of eosinophil differentiation 4.283928e-3
GO:0045234 protein palmitoleylation 4.283928e-3
GO:0006948 induction by virus of host cell-cell fusion 4.283928e-3
GO:0007321 sperm displacement 4.283928e-3
GO:0031591 wybutosine biosynthetic process 4.283928e-3
GO:0060579 ventral spinal cord interneuron fate commitment 4.292439e-3
GO:0050703 interleukin-1 alpha secretion 4.346014e-3
GO:0070946 neutrophil mediated killing of gram-positive bacterium 4.346014e-3
GO:0090344 negative regulation of cell aging 4.442666e-3
GO:0007010 cytoskeleton organization 4.511547e-3
GO:0006449 regulation of translational termination 4.577700e-3
GO:0061031 endodermal digestive tract morphogenesis 4.640870e-3
GO:0051299 centrosome separation 4.685876e-3
GO:0006552 leucine catabolic process 4.685876e-3
GO:0006304 DNA modification 4.761392e-3
GO:0030198 extracellular matrix organization 4.834226e-3
GO:0046724 oxalic acid secretion 4.868935e-3
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 4.868935e-3
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 4.868935e-3
GO:0060349 bone morphogenesis 4.899299e-3
GO:0015864 pyrimidine nucleoside transport 4.922161e-3
GO:0032916 positive regulation of transforming growth factor beta3 production 4.925861e-3
GO:0034329 cell junction assembly 4.958154e-3
GO:0009189 deoxyribonucleoside diphosphate biosynthetic process 4.964624e-3
GO:0021514 ventral spinal cord interneuron differentiation 4.970470e-3
GO:0097150 neuronal stem cell maintenance 4.981121e-3
GO:0032863 activation of Rac GTPase activity 4.981121e-3
GO:0048663 neuron fate commitment 4.998866e-3
GO:0060367 sagittal suture morphogenesis 5.001153e-3
GO:0060873 anterior semicircular canal development 5.001153e-3
GO:0070242 thymocyte apoptosis 5.001153e-3
GO:0060366 lambdoid suture morphogenesis 5.001153e-3
GO:0060875 lateral semicircular canal development 5.001153e-3
GO:0034959 endothelin maturation 5.001153e-3
GO:0010816 calcitonin catabolic process 5.001153e-3
GO:0010814 substance P catabolic process 5.001153e-3
GO:0022018 lateral ganglionic eminence cell proliferation 5.001153e-3
GO:0010626 negative regulation of Schwann cell proliferation 5.015604e-3
GO:0060732 positive regulation of inositol phosphate biosynthetic process 5.042491e-3
GO:0061034 olfactory bulb mitral cell layer development 5.042743e-3
GO:0007412 axon target recognition 5.071394e-3
GO:0007595 lactation 5.111472e-3
GO:0061298 retina vasculature development in camera-type eye 5.145101e-3
GO:0006688 glycosphingolipid biosynthetic process 5.183954e-3
GO:0046364 monosaccharide biosynthetic process 5.221961e-3
GO:0070989 oxidative demethylation 5.297555e-3
GO:0032856 activation of Ras GTPase activity 5.349909e-3
GO:2000045 regulation of G1/S transition of mitotic cell cycle 5.372843e-3
GO:0071299 cellular response to vitamin A 5.377722e-3
GO:0001973 adenosine receptor signaling pathway 5.415218e-3
GO:0019322 pentose biosynthetic process 5.453460e-3
GO:0043242 negative regulation of protein complex disassembly 5.460643e-3
GO:0006107 oxaloacetate metabolic process 5.480118e-3
GO:0003180 aortic valve morphogenesis 5.506797e-3
GO:0061360 optic chiasma development 5.535240e-3
GO:0035799 ureter maturation 5.535240e-3
GO:2000597 positive regulation of optic nerve formation 5.535240e-3
GO:0021650 vestibulocochlear nerve formation 5.535240e-3
GO:0006021 inositol biosynthetic process 5.535240e-3
GO:0021633 optic nerve structural organization 5.535240e-3
GO:0007586 digestion 5.571671e-3
GO:0046456 icosanoid biosynthetic process 5.630484e-3
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 5.664313e-3
GO:0003158 endothelium development 5.685485e-3
GO:0060620 regulation of cholesterol import 5.788634e-3
GO:0019348 dolichol metabolic process 5.822707e-3
GO:0090179 planar cell polarity pathway involved in neural tube closure 5.851234e-3
GO:0044275 cellular carbohydrate catabolic process 5.854231e-3
GO:0019369 arachidonic acid metabolic process 5.900765e-3
GO:0090103 cochlea morphogenesis 5.914104e-3
GO:0043303 mast cell degranulation 6.137658e-3
GO:0001738 morphogenesis of a polarized epithelium 6.175731e-3
GO:0048843 negative regulation of axon extension involved in axon guidance 6.205291e-3
GO:0010535 positive regulation of activation of JAK2 kinase activity 6.322169e-3
GO:0045604 regulation of epidermal cell differentiation 6.365312e-3
GO:2000369 regulation of clathrin-mediated endocytosis 6.368282e-3
GO:0001880 Mullerian duct regression 6.368282e-3
GO:0060708 spongiotrophoblast differentiation 6.383845e-3
GO:0060364 frontal suture morphogenesis 6.384615e-3
GO:0000022 mitotic spindle elongation 6.398854e-3
GO:0061383 trabecula morphogenesis 6.448767e-3
GO:0002077 acrosome matrix dispersal 6.512141e-3
GO:0030321 transepithelial chloride transport 6.566617e-3
GO:0007440 foregut morphogenesis 6.654117e-3
GO:0051066 dihydrobiopterin metabolic process 6.674815e-3
GO:0046390 ribose phosphate biosynthetic process 6.674815e-3
GO:0046339 diacylglycerol metabolic process 6.731820e-3
GO:0070527 platelet aggregation 6.735251e-3
GO:0060448 dichotomous subdivision of terminal units involved in lung branching 6.767225e-3
GO:0050432 catecholamine secretion 6.767225e-3
GO:0045198 establishment of epithelial cell apical/basal polarity 6.920177e-3
GO:0060621 negative regulation of cholesterol import 6.920177e-3
GO:0048521 negative regulation of behavior 6.996380e-3
GO:0002019 regulation of renal output by angiotensin 7.077866e-3
GO:0007501 mesodermal cell fate specification 7.116094e-3
GO:0009912 auditory receptor cell fate commitment 7.141024e-3
GO:0045662 negative regulation of myoblast differentiation 7.151465e-3
GO:0042737 drug catabolic process 7.168677e-3
GO:0021520 spinal cord motor neuron cell fate specification 7.222039e-3
GO:0006348 chromatin silencing at telomere 7.255562e-3
GO:0042631 cellular response to water deprivation 7.255562e-3
GO:0006784 heme a biosynthetic process 7.284290e-3
GO:0035545 determination of left/right asymmetry in nervous system 7.284290e-3
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 7.284290e-3
GO:0002642 positive regulation of immunoglobulin biosynthetic process 7.284290e-3
GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway 7.428170e-3
GO:2001054 negative regulation of mesenchymal cell apoptosis 7.428170e-3
GO:0015684 ferrous iron transport 7.428170e-3
GO:0010900 negative regulation of phosphatidylcholine catabolic process 7.428170e-3
GO:0005999 xylulose biosynthetic process 7.428170e-3
GO:0043583 ear development 7.670860e-3
GO:0051291 protein heterooligomerization 7.782245e-3
GO:0044236 multicellular organismal metabolic process 7.786280e-3
GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway 7.791072e-3
GO:0002443 leukocyte mediated immunity 7.799119e-3
GO:0046434 organophosphate catabolic process 7.844556e-3
GO:0046185 aldehyde catabolic process 7.989948e-3
GO:0033128 negative regulation of histone phosphorylation 8.091311e-3
GO:0071526 semaphorin-plexin signaling pathway 8.158682e-3
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 8.187049e-3
GO:2000378 negative regulation of reactive oxygen species metabolic process 8.263721e-3
GO:0010832 negative regulation of myotube differentiation 8.288754e-3
GO:0046626 regulation of insulin receptor signaling pathway 8.386342e-3
GO:0051890 regulation of cardioblast differentiation 8.413798e-3
GO:0031529 ruffle organization 8.464587e-3
GO:0048855 adenohypophysis morphogenesis 8.469737e-3
GO:0042747 circadian sleep/wake cycle, REM sleep 8.469737e-3
GO:0021771 lateral geniculate nucleus development 8.469737e-3
GO:0018160 peptidyl-pyrromethane cofactor linkage 8.469737e-3
GO:0070489 T cell aggregation 8.562968e-3
GO:0006420 arginyl-tRNA aminoacylation 8.562968e-3
GO:0045820 negative regulation of glycolysis 8.588496e-3
GO:0006382 adenosine to inosine editing 8.624435e-3
GO:0090026 positive regulation of monocyte chemotaxis 8.651644e-3
GO:0060177 regulation of angiotensin metabolic process 8.651644e-3
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development 8.651644e-3
GO:0014014 negative regulation of gliogenesis 8.781512e-3
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 8.875204e-3
GO:0006690 icosanoid metabolic process 8.892469e-3
GO:0043383 negative T cell selection 8.985049e-3
GO:0018993 somatic sex determination 9.128671e-3
GO:0019319 hexose biosynthetic process 9.173897e-3
GO:0007224 smoothened signaling pathway 9.212485e-3
GO:0030195 negative regulation of blood coagulation 9.212727e-3
GO:0001909 leukocyte mediated cytotoxicity 9.221589e-3
GO:0071545 inositol phosphate catabolic process 9.236656e-3
GO:0031575 mitotic cell cycle G1/S transition checkpoint 9.369097e-3
GO:0001516 prostaglandin biosynthetic process 9.440864e-3
GO:0003300 cardiac muscle hypertrophy 9.454100e-3
GO:0002444 myeloid leukocyte mediated immunity 9.462760e-3
GO:0034063 stress granule assembly 9.528260e-3
GO:0043084 penile erection 9.540665e-3
GO:2000778 positive regulation of interleukin-6 secretion 9.561141e-3
GO:0045055 regulated secretory pathway 9.657304e-3
GO:0097084 vascular smooth muscle cell development 9.682835e-3
GO:0072075 metanephric mesenchyme development 9.740678e-3
GO:0090251 protein localization involved in establishment of planar polarity 9.769362e-3
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 9.835225e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0034623 cellular macromolecular complex disassembly 3.672015e-9
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 1.878044e-8
GO:0055090 acylglycerol homeostasis 2.020598e-8
GO:0044241 lipid digestion 2.529679e-8
GO:0032984 macromolecular complex disassembly 3.369638e-8
GO:0030300 regulation of intestinal cholesterol absorption 7.375336e-8
GO:0006869 lipid transport 1.573791e-7
GO:0015914 phospholipid transport 1.666248e-7
GO:0033344 cholesterol efflux 2.612991e-7
GO:0019532 oxalate transport 4.178106e-7
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 7.455375e-7
GO:0071702 organic substance transport 8.860004e-7
GO:0046470 phosphatidylcholine metabolic process 1.133542e-6
GO:0055010 ventricular cardiac muscle tissue morphogenesis 1.515472e-6
GO:0060192 negative regulation of lipase activity 1.725090e-6
GO:0051937 catecholamine transport 1.860829e-6
GO:0055088 lipid homeostasis 1.861012e-6
GO:0033700 phospholipid efflux 1.861714e-6
GO:0010876 lipid localization 2.289184e-6
GO:0071845 cellular component disassembly at cellular level 3.216944e-6
GO:0060415 muscle tissue morphogenesis 4.256581e-6
GO:0003229 ventricular cardiac muscle tissue development 4.269464e-6
GO:0048747 muscle fiber development 4.547156e-6
GO:0044240 multicellular organismal lipid catabolic process 5.800033e-6
GO:0022411 cellular component disassembly 7.591388e-6
GO:0032374 regulation of cholesterol transport 8.032584e-6
GO:0065005 protein-lipid complex assembly 8.106917e-6
GO:0043624 cellular protein complex disassembly 8.637495e-6
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 9.826165e-6
GO:0007522 visceral muscle development 1.006524e-5
GO:0043691 reverse cholesterol transport 1.250836e-5
GO:0042439 ethanolamine-containing compound metabolic process 1.308878e-5
GO:0045924 regulation of female receptivity 2.715116e-5
GO:0055008 cardiac muscle tissue morphogenesis 2.828016e-5
GO:0032375 negative regulation of cholesterol transport 2.957481e-5
GO:0015844 monoamine transport 3.324451e-5
GO:0048008 platelet-derived growth factor receptor signaling pathway 3.811351e-5
GO:0071071 regulation of phospholipid biosynthetic process 4.131960e-5
GO:0070286 axonemal dynein complex assembly 4.533859e-5
GO:0071072 negative regulation of phospholipid biosynthetic process 4.702624e-5
GO:0030301 cholesterol transport 5.015495e-5
GO:0030049 muscle filament sliding 5.267493e-5
GO:0045226 extracellular polysaccharide biosynthetic process 5.591204e-5
GO:0002077 acrosome matrix dispersal 5.591204e-5
GO:0042632 cholesterol homeostasis 6.158800e-5
GO:0045749 negative regulation of S phase of mitotic cell cycle 6.605118e-5
GO:0043241 protein complex disassembly 7.200921e-5
GO:0007621 negative regulation of female receptivity 7.235356e-5
GO:0031329 regulation of cellular catabolic process 7.735168e-5
GO:0019987 negative regulation of anti-apoptosis 8.304796e-5
GO:0042178 xenobiotic catabolic process 9.317525e-5
GO:0006629 lipid metabolic process 9.487998e-5
GO:0051005 negative regulation of lipoprotein lipase activity 9.984325e-5
GO:0010873 positive regulation of cholesterol esterification 1.090361e-4
GO:0072015 glomerular visceral epithelial cell development 1.125649e-4
GO:0000902 cell morphogenesis 1.205338e-4
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 1.249174e-4
GO:0002921 negative regulation of humoral immune response 1.265310e-4
GO:0048644 muscle organ morphogenesis 1.288197e-4
GO:0009894 regulation of catabolic process 1.313722e-4
GO:0030449 regulation of complement activation 1.440215e-4
GO:0007290 spermatid nucleus elongation 1.469941e-4
GO:0060711 labyrinthine layer development 1.528100e-4
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 1.639362e-4
GO:0033057 multicellular organismal reproductive behavior 1.773411e-4
GO:0045933 positive regulation of muscle contraction 1.813996e-4
GO:0006540 glutamate decarboxylation to succinate 1.817651e-4
GO:0017158 regulation of calcium ion-dependent exocytosis 2.006591e-4
GO:0050996 positive regulation of lipid catabolic process 2.139972e-4
GO:0032368 regulation of lipid transport 2.293042e-4
GO:0072284 metanephric S-shaped body morphogenesis 2.351123e-4
GO:0072278 metanephric comma-shaped body morphogenesis 2.351123e-4
GO:0060137 maternal process involved in parturition 2.351123e-4
GO:0032571 response to vitamin K 2.376604e-4
GO:0032835 glomerulus development 2.403512e-4
GO:0042339 keratan sulfate metabolic process 2.416115e-4
GO:0001844 protein insertion into mitochondrial membrane involved in induction of apoptosis 2.416115e-4
GO:0006337 nucleosome disassembly 2.446441e-4
GO:0007008 outer mitochondrial membrane organization 2.449552e-4
GO:0045930 negative regulation of mitotic cell cycle 2.613679e-4
GO:0060180 female mating behavior 2.634853e-4
GO:0043314 negative regulation of neutrophil degranulation 2.636073e-4
GO:0006982 response to lipid hydroperoxide 2.636073e-4
GO:0070585 protein localization in mitochondrion 2.864924e-4
GO:0001570 vasculogenesis 2.938415e-4
GO:0000212 meiotic spindle organization 2.944419e-4
GO:0060621 negative regulation of cholesterol import 3.064954e-4
GO:0019637 organophosphate metabolic process 3.137891e-4
GO:0055091 phospholipid homeostasis 3.248526e-4
GO:0071827 plasma lipoprotein particle organization 3.464684e-4
GO:0015872 dopamine transport 3.707660e-4
GO:0034442 regulation of lipoprotein oxidation 3.798122e-4
GO:0015850 organic alcohol transport 3.887240e-4
GO:0006644 phospholipid metabolic process 3.916476e-4
GO:0010623 developmental programmed cell death 4.067190e-4
GO:0045618 positive regulation of keratinocyte differentiation 4.073840e-4
GO:0002358 B cell homeostatic proliferation 4.081382e-4
GO:0055009 atrial cardiac muscle tissue morphogenesis 4.184929e-4
GO:0014819 regulation of skeletal muscle contraction 4.411715e-4
GO:0032696 negative regulation of interleukin-13 production 4.484102e-4
GO:0002027 regulation of heart rate 4.554118e-4
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 4.558029e-4
GO:0015881 creatine transport 4.558445e-4
GO:0031331 positive regulation of cellular catabolic process 4.593516e-4
GO:0045606 positive regulation of epidermal cell differentiation 4.680472e-4
GO:0010761 fibroblast migration 5.106611e-4
GO:0051004 regulation of lipoprotein lipase activity 5.109494e-4
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 5.454242e-4
GO:0030837 negative regulation of actin filament polymerization 5.867751e-4
GO:0032970 regulation of actin filament-based process 6.006135e-4
GO:0015908 fatty acid transport 6.159772e-4
GO:0003208 cardiac ventricle morphogenesis 6.359803e-4
GO:0070244 negative regulation of thymocyte apoptosis 6.384970e-4
GO:0021707 cerebellar granule cell differentiation 6.575316e-4
GO:0007258 JUN phosphorylation 6.575316e-4
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 6.765443e-4
GO:0046487 glyoxylate metabolic process 6.765443e-4
GO:0035441 cell migration involved in vasculogenesis 6.780990e-4
GO:0010872 regulation of cholesterol esterification 6.889709e-4
GO:0044255 cellular lipid metabolic process 6.928884e-4
GO:0070252 actin-mediated cell contraction 6.964774e-4
GO:0048739 cardiac muscle fiber development 6.964774e-4
GO:0003206 cardiac chamber morphogenesis 7.178628e-4
GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 7.388349e-4
GO:0008217 regulation of blood pressure 7.856396e-4
GO:0032956 regulation of actin cytoskeleton organization 8.070816e-4
GO:0035725 sodium ion transmembrane transport 8.313470e-4
GO:0030299 intestinal cholesterol absorption 8.420352e-4
GO:0006471 protein ADP-ribosylation 8.585130e-4
GO:0032989 cellular component morphogenesis 8.741455e-4
GO:0050746 regulation of lipoprotein metabolic process 8.899633e-4
GO:0045989 positive regulation of striated muscle contraction 8.951241e-4
GO:0009098 leucine biosynthetic process 9.174441e-4
GO:0006550 isoleucine catabolic process 9.174441e-4
GO:0021575 hindbrain morphogenesis 9.246055e-4
GO:0072655 establishment of protein localization in mitochondrion 9.433881e-4
GO:0006656 phosphatidylcholine biosynthetic process 9.559356e-4
GO:0003338 metanephros morphogenesis 1.022578e-3
GO:0003205 cardiac chamber development 1.041779e-3
GO:0044106 cellular amine metabolic process 1.063761e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 1.072130e-3
GO:0044058 regulation of digestive system process 1.074523e-3
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 1.111421e-3
GO:0019255 glucose 1-phosphate metabolic process 1.131487e-3
GO:0033275 actin-myosin filament sliding 1.147877e-3
GO:0050994 regulation of lipid catabolic process 1.150321e-3
GO:0050432 catecholamine secretion 1.167582e-3
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 1.179783e-3
GO:0048340 paraxial mesoderm morphogenesis 1.201547e-3
GO:0060712 spongiotrophoblast layer development 1.236112e-3
GO:0042448 progesterone metabolic process 1.285968e-3
GO:0008542 visual learning 1.309655e-3
GO:0048241 epinephrine transport 1.327224e-3
GO:0010896 regulation of triglyceride catabolic process 1.337529e-3
GO:0034369 plasma lipoprotein particle remodeling 1.339146e-3
GO:0002227 innate immune response in mucosa 1.344406e-3
GO:0010817 regulation of hormone levels 1.349900e-3
GO:0045723 positive regulation of fatty acid biosynthetic process 1.354561e-3
GO:0006549 isoleucine metabolic process 1.373423e-3
GO:0060716 labyrinthine layer blood vessel development 1.384971e-3
GO:0034380 high-density lipoprotein particle assembly 1.429446e-3
GO:0021683 cerebellar granular layer morphogenesis 1.498822e-3
GO:0031109 microtubule polymerization or depolymerization 1.498988e-3
GO:0002897 positive regulation of central B cell tolerance induction 1.593982e-3
GO:0002508 central tolerance induction 1.593982e-3
GO:0001777 T cell homeostatic proliferation 1.593982e-3
GO:0045578 negative regulation of B cell differentiation 1.602205e-3
GO:0032836 glomerular basement membrane development 1.602205e-3
GO:0072273 metanephric nephron morphogenesis 1.607572e-3
GO:0043313 regulation of neutrophil degranulation 1.626719e-3
GO:0009308 amine metabolic process 1.669574e-3
GO:0070328 triglyceride homeostasis 1.675280e-3
GO:0031427 response to methotrexate 1.675363e-3
GO:0021587 cerebellum morphogenesis 1.695491e-3
GO:0031398 positive regulation of protein ubiquitination 1.708878e-3
GO:0060066 oviduct development 1.746965e-3
GO:0060191 regulation of lipase activity 1.748315e-3
GO:0048741 skeletal muscle fiber development 1.756473e-3
GO:0034377 plasma lipoprotein particle assembly 1.808998e-3
GO:0072112 glomerular visceral epithelial cell differentiation 1.818677e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.846455e-3
GO:0043988 histone H3-S28 phosphorylation 1.846455e-3
GO:0043987 histone H3-S10 phosphorylation 1.846455e-3
GO:0032929 negative regulation of superoxide anion generation 1.849255e-3
GO:0007140 male meiosis 1.878245e-3
GO:0032463 negative regulation of protein homooligomerization 1.904717e-3
GO:0010989 negative regulation of low-density lipoprotein particle clearance 1.906703e-3
GO:0030833 regulation of actin filament polymerization 1.939647e-3
GO:0006415 translational termination 1.984947e-3
GO:0003065 positive regulation of heart rate by epinephrine 2.000178e-3
GO:0051323 metaphase 2.000178e-3
GO:0016125 sterol metabolic process 2.006453e-3
GO:0061028 establishment of endothelial barrier 2.031270e-3
GO:0032048 cardiolipin metabolic process 2.035186e-3
GO:0003231 cardiac ventricle development 2.051207e-3
GO:0032233 positive regulation of actin filament bundle assembly 2.056704e-3
GO:0009395 phospholipid catabolic process 2.059273e-3
GO:0006659 phosphatidylserine biosynthetic process 2.207347e-3
GO:0051403 stress-activated MAPK cascade 2.207347e-3
GO:0006576 cellular biogenic amine metabolic process 2.305848e-3
GO:0097035 regulation of membrane lipid distribution 2.310255e-3
GO:0001970 positive regulation of activation of membrane attack complex 2.310255e-3
GO:0006140 regulation of nucleotide metabolic process 2.312333e-3
GO:0030728 ovulation 2.338117e-3
GO:0030046 parallel actin filament bundle assembly 2.351260e-3
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 2.380600e-3
GO:0045019 negative regulation of nitric oxide biosynthetic process 2.413362e-3
GO:0016042 lipid catabolic process 2.418972e-3
GO:0014015 positive regulation of gliogenesis 2.439066e-3
GO:0006997 nucleus organization 2.471669e-3
GO:0014020 primary neural tube formation 2.474078e-3
GO:0050748 negative regulation of lipoprotein metabolic process 2.478166e-3
GO:0033194 response to hydroperoxide 2.538188e-3
GO:0051608 histamine transport 2.539948e-3
GO:0045022 early endosome to late endosome transport 2.584881e-3
GO:0090207 regulation of triglyceride metabolic process 2.596899e-3
GO:0015909 long-chain fatty acid transport 2.596899e-3
GO:0032714 negative regulation of interleukin-5 production 2.671591e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 2.682083e-3
GO:0070474 positive regulation of uterine smooth muscle contraction 2.851256e-3
GO:0030835 negative regulation of actin filament depolymerization 2.855434e-3
GO:0051261 protein depolymerization 2.911133e-3
GO:0042304 regulation of fatty acid biosynthetic process 2.945889e-3
GO:0048711 positive regulation of astrocyte differentiation 2.981004e-3
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 2.990412e-3
GO:0021546 rhombomere development 3.009997e-3
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 3.016786e-3
GO:0071354 cellular response to interleukin-6 3.044945e-3
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 3.074824e-3
GO:0043171 peptide catabolic process 3.081368e-3
GO:0007182 common-partner SMAD protein phosphorylation 3.081368e-3
GO:0001885 endothelial cell development 3.106359e-3
GO:0042490 mechanoreceptor differentiation 3.125280e-3
GO:0019233 sensory perception of pain 3.168265e-3
GO:0043587 tongue morphogenesis 3.231300e-3
GO:0000305 response to oxygen radical 3.292382e-3
GO:0032369 negative regulation of lipid transport 3.293614e-3
GO:0035659 Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells 3.307114e-3
GO:0014719 satellite cell activation 3.307114e-3
GO:0009258 10-formyltetrahydrofolate catabolic process 3.307114e-3
GO:0010985 negative regulation of lipoprotein particle clearance 3.307458e-3
GO:0008272 sulfate transport 3.307458e-3
GO:0060620 regulation of cholesterol import 3.404258e-3
GO:0021612 facial nerve structural organization 3.408755e-3
GO:0045332 phospholipid translocation 3.408755e-3
GO:0045585 positive regulation of cytotoxic T cell differentiation 3.441060e-3
GO:0007274 neuromuscular synaptic transmission 3.458704e-3
GO:0048339 paraxial mesoderm development 3.469862e-3
GO:0035813 regulation of renal sodium excretion 3.471215e-3
GO:0072125 negative regulation of glomerular mesangial cell proliferation 3.496885e-3
GO:0043046 DNA methylation involved in gamete generation 3.570783e-3
GO:0070102 interleukin-6-mediated signaling pathway 3.673896e-3
GO:0008207 C21-steroid hormone metabolic process 3.674783e-3
GO:0032049 cardiolipin biosynthetic process 3.682507e-3
GO:0010977 negative regulation of neuron projection development 3.699344e-3
GO:0021978 telencephalon regionalization 3.723960e-3
GO:0033121 regulation of purine nucleotide catabolic process 3.818300e-3
GO:0032713 negative regulation of interleukin-4 production 3.818816e-3
GO:0032231 regulation of actin filament bundle assembly 3.838855e-3
GO:0008203 cholesterol metabolic process 3.856641e-3
GO:0002446 neutrophil mediated immunity 3.859539e-3
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway 3.964437e-3
GO:0008535 respiratory chain complex IV assembly 3.966481e-3
GO:0070233 negative regulation of T cell apoptosis 3.993219e-3
GO:0051583 dopamine uptake 4.065204e-3
GO:0051204 protein insertion into mitochondrial membrane 4.065204e-3
GO:0002331 pre-B cell allelic exclusion 4.065204e-3
GO:0051125 regulation of actin nucleation 4.136001e-3
GO:0017157 regulation of exocytosis 4.156455e-3
GO:0003007 heart morphogenesis 4.199866e-3
GO:0060674 placenta blood vessel development 4.207210e-3
GO:0014824 artery smooth muscle contraction 4.229578e-3
GO:0060290 transdifferentiation 4.266289e-3
GO:0032509 endosome transport via multivesicular body sorting pathway 4.266289e-3
GO:0021535 cell migration in hindbrain 4.301897e-3
GO:0006012 galactose metabolic process 4.441392e-3
GO:0097006 regulation of plasma lipoprotein particle levels 4.446399e-3
GO:0050892 intestinal absorption 4.583802e-3
GO:0031333 negative regulation of protein complex assembly 4.642120e-3
GO:0043086 negative regulation of catalytic activity 4.646817e-3
GO:0003156 regulation of organ formation 4.672163e-3
GO:0031098 stress-activated protein kinase signaling cascade 4.708745e-3
GO:0042177 negative regulation of protein catabolic process 4.731279e-3
GO:0001969 regulation of activation of membrane attack complex 4.829409e-3
GO:0046544 development of secondary male sexual characteristics 4.831602e-3
GO:0006551 leucine metabolic process 4.877080e-3
GO:0090074 negative regulation of protein homodimerization activity 4.877080e-3
GO:0035265 organ growth 4.882017e-3
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 5.028129e-3
GO:0006546 glycine catabolic process 5.028129e-3
GO:0008064 regulation of actin polymerization or depolymerization 5.042297e-3
GO:0006941 striated muscle contraction 5.087163e-3
GO:0010815 bradykinin catabolic process 5.133926e-3
GO:0030317 sperm motility 5.235981e-3
GO:0042157 lipoprotein metabolic process 5.389342e-3
GO:2001076 positive regulation of metanephric ureteric bud development 5.463585e-3
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 5.463585e-3
GO:0007356 thorax and anterior abdomen determination 5.463585e-3
GO:0051894 positive regulation of focal adhesion assembly 5.470055e-3
GO:0072109 glomerular mesangium development 5.494046e-3
GO:0032365 intracellular lipid transport 5.494046e-3
GO:0044062 regulation of excretion 5.502741e-3
GO:0021871 forebrain regionalization 5.528917e-3
GO:0051055 negative regulation of lipid biosynthetic process 5.558056e-3
GO:0007440 foregut morphogenesis 5.800145e-3
GO:0001667 ameboidal cell migration 5.868196e-3
GO:0021569 rhombomere 3 development 5.880636e-3
GO:0060286 flagellar cell motility 5.924287e-3
GO:2000079 regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 5.924287e-3
GO:0018343 protein farnesylation 5.924287e-3
GO:0015891 siderophore transport 5.924287e-3
GO:0002635 negative regulation of germinal center formation 5.924287e-3
GO:0043029 T cell homeostasis 5.934346e-3
GO:0060923 cardiac muscle cell fate commitment 6.052813e-3
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 6.052813e-3
GO:0070212 protein poly-ADP-ribosylation 6.066247e-3
GO:0032212 positive regulation of telomere maintenance via telomerase 6.066247e-3
GO:0031296 B cell costimulation 6.066247e-3
GO:0032787 monocarboxylic acid metabolic process 6.133645e-3
GO:0010984 regulation of lipoprotein particle clearance 6.167252e-3
GO:0018105 peptidyl-serine phosphorylation 6.206077e-3
GO:0014034 neural crest cell fate commitment 6.221289e-3
GO:0006705 mineralocorticoid biosynthetic process 6.221289e-3
GO:0032862 activation of Rho GTPase activity 6.300621e-3
GO:0001709 cell fate determination 6.372335e-3
GO:0007517 muscle organ development 6.469235e-3
GO:0009912 auditory receptor cell fate commitment 6.486048e-3
GO:0051129 negative regulation of cellular component organization 6.562169e-3
GO:0031581 hemidesmosome assembly 6.568210e-3
GO:0072668 tubulin complex biogenesis 6.634698e-3
GO:0048144 fibroblast proliferation 6.713969e-3
GO:0001845 phagolysosome assembly 6.713969e-3
GO:0046666 retinal cell programmed cell death 6.713969e-3
GO:0051493 regulation of cytoskeleton organization 6.716535e-3
GO:0000578 embryonic axis specification 6.743422e-3
GO:0006825 copper ion transport 6.779349e-3
GO:0072049 comma-shaped body morphogenesis 6.781793e-3
GO:0072050 S-shaped body morphogenesis 6.781793e-3
GO:0019934 cGMP-mediated signaling 6.842338e-3
GO:0045923 positive regulation of fatty acid metabolic process 6.864267e-3
GO:0045687 positive regulation of glial cell differentiation 7.017575e-3
GO:0021553 olfactory nerve development 7.172119e-3
GO:0009082 branched chain family amino acid biosynthetic process 7.172119e-3
GO:0060113 inner ear receptor cell differentiation 7.189730e-3
GO:0035802 adrenal cortex formation 7.343438e-3
GO:0014807 regulation of somitogenesis 7.343438e-3
GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 7.343438e-3
GO:0001835 blastocyst hatching 7.445661e-3
GO:0015966 diadenosine tetraphosphate biosynthetic process 7.479034e-3
GO:0021586 pons maturation 7.479034e-3
GO:0010511 regulation of phosphatidylinositol biosynthetic process 7.538065e-3
GO:2000573 positive regulation of DNA biosynthetic process 7.538065e-3
GO:0002002 regulation of angiotensin levels in blood 7.538065e-3
GO:0035634 response to stilbenoid 7.719859e-3
GO:0009081 branched chain family amino acid metabolic process 7.719859e-3
GO:0042747 circadian sleep/wake cycle, REM sleep 7.807253e-3
GO:0019388 galactose catabolic process 7.807253e-3
GO:0006767 water-soluble vitamin metabolic process 7.854407e-3
GO:0007141 male meiosis I 7.863675e-3
GO:0032272 negative regulation of protein polymerization 7.926492e-3
GO:0006998 nuclear envelope organization 7.935514e-3
GO:0007528 neuromuscular junction development 8.022884e-3
GO:0010948 negative regulation of cell cycle process 8.029779e-3
GO:0042246 tissue regeneration 8.072050e-3
GO:0071287 cellular response to manganese ion 8.128609e-3
GO:0010159 specification of organ position 8.128609e-3
GO:0031558 induction of apoptosis in response to chemical stimulus 8.128609e-3
GO:0033692 cellular polysaccharide biosynthetic process 8.243098e-3
GO:0051336 regulation of hydrolase activity 8.259974e-3
GO:0021675 nerve development 8.272365e-3
GO:0035234 germ cell programmed cell death 8.294782e-3
GO:0051693 actin filament capping 8.341255e-3
GO:0001779 natural killer cell differentiation 8.731227e-3
GO:0060177 regulation of angiotensin metabolic process 8.756324e-3
GO:0007412 axon target recognition 8.783382e-3
GO:0048597 post-embryonic camera-type eye morphogenesis 8.783382e-3
GO:0009642 response to light intensity 8.935720e-3
GO:0006420 arginyl-tRNA aminoacylation 8.935720e-3
GO:0003094 glomerular filtration 8.935720e-3
GO:0008202 steroid metabolic process 8.941882e-3
GO:0051494 negative regulation of cytoskeleton organization 9.054403e-3
GO:0060561 apoptosis involved in morphogenesis 9.102984e-3
GO:0010987 negative regulation of high-density lipoprotein particle clearance 9.130288e-3
GO:0010897 negative regulation of triglyceride catabolic process 9.130288e-3
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 9.130288e-3
GO:0001843 neural tube closure 9.343322e-3
GO:0060052 neurofilament cytoskeleton organization 9.383746e-3
GO:0072006 nephron development 9.512496e-3
GO:0021604 cranial nerve structural organization 9.520634e-3
GO:2001054 negative regulation of mesenchymal cell apoptosis 9.826077e-3
GO:0009110 vitamin biosynthetic process 9.851838e-3
GO:0071173 spindle assembly checkpoint 9.899266e-3
GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 9.962913e-3
GO:0060695 negative regulation of cholesterol transporter activity 9.962913e-3
GO:2000270 negative regulation of fibroblast apoptosis 9.962913e-3
GO:2000271 positive regulation of fibroblast apoptosis 9.962913e-3
GO:0021570 rhombomere 4 development 9.962913e-3
GO:0044345 stromal-epithelial cell signaling involved in prostate gland development 9.962913e-3
GO:0006097 glyoxylate cycle 9.962913e-3
GO:0015759 beta-glucoside transport 9.962913e-3
GO:0045956 positive regulation of calcium ion-dependent exocytosis 9.986258e-3
GO:0043366 beta selection 1.014484e-2
GO:0043407 negative regulation of MAP kinase activity 1.020440e-2
GO:0071104 response to interleukin-9 1.020755e-2
GO:0061005 cell differentiation involved in kidney development 1.026778e-2
GO:0006939 smooth muscle contraction 1.036923e-2
GO:0015862 uridine transport 1.045796e-2
GO:0035567 non-canonical Wnt receptor signaling pathway 1.046894e-2
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.055350e-2
GO:0060376 positive regulation of mast cell differentiation 1.059490e-2
GO:0045626 negative regulation of T-helper 1 cell differentiation 1.059490e-2
GO:0002125 maternal aggressive behavior 1.059490e-2
GO:0000238 zygotene 1.059490e-2
GO:0001821 histamine secretion 1.064240e-2
GO:0010982 regulation of high-density lipoprotein particle clearance 1.070264e-2
GO:0015693 magnesium ion transport 1.087498e-2
GO:0071529 cementum mineralization 1.105079e-2
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 1.105079e-2
GO:0090084 negative regulation of inclusion body assembly 1.105079e-2
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.105079e-2
GO:0006867 asparagine transport 1.105079e-2
GO:0032796 uropod organization 1.105502e-2
GO:0022007 convergent extension involved in neural plate elongation 1.105502e-2
GO:0021796 cerebral cortex regionalization 1.105502e-2
GO:0046426 negative regulation of JAK-STAT cascade 1.111166e-2
GO:0048839 inner ear development 1.113012e-2
GO:0001975 response to amphetamine 1.123491e-2
GO:0007052 mitotic spindle organization 1.127824e-2
GO:0006626 protein targeting to mitochondrion 1.147932e-2
GO:0032876 negative regulation of DNA endoreduplication 1.160303e-2
GO:0072012 glomerulus vasculature development 1.186222e-2
GO:0060136 embryonic process involved in female pregnancy 1.188194e-2
GO:0032488 Cdc42 protein signal transduction 1.188194e-2
GO:0014029 neural crest formation 1.200976e-2
GO:0030307 positive regulation of cell growth 1.202070e-2
GO:0051586 positive regulation of dopamine uptake 1.236429e-2
GO:0032966 negative regulation of collagen biosynthetic process 1.236429e-2
GO:0019430 removal of superoxide radicals 1.242334e-2
GO:0015874 norepinephrine transport 1.242478e-2
GO:0045040 protein import into mitochondrial outer membrane 1.242478e-2
GO:0002444 myeloid leukocyte mediated immunity 1.265697e-2
GO:0042267 natural killer cell mediated cytotoxicity 1.270596e-2
GO:0000303 response to superoxide 1.284490e-2
GO:0035249 synaptic transmission, glutamatergic 1.284490e-2
GO:0060606 tube closure 1.286703e-2
GO:0008643 carbohydrate transport 1.288117e-2
GO:0006573 valine metabolic process 1.291459e-2
GO:0031577 spindle checkpoint 1.291459e-2
GO:0030832 regulation of actin filament length 1.293110e-2
GO:0007386 compartment pattern specification 1.312308e-2
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1.313702e-2
GO:0003350 pulmonary myocardium development 1.324083e-2
GO:0071715 icosanoid transport 1.329348e-2
GO:0002026 regulation of the force of heart contraction 1.330101e-2
GO:0030030 cell projection organization 1.330582e-2
GO:0001895 retina homeostasis 1.334592e-2
GO:2000104 negative regulation of DNA-dependent DNA replication 1.334592e-2
GO:0046716 muscle cell homeostasis 1.335076e-2
GO:2001037 positive regulation of tongue muscle cell differentiation 1.335767e-2
GO:0051639 actin filament network formation 1.335767e-2
GO:0006650 glycerophospholipid metabolic process 1.338327e-2
GO:0045428 regulation of nitric oxide biosynthetic process 1.347906e-2
GO:0007403 glial cell fate determination 1.348348e-2
GO:0032000 positive regulation of fatty acid beta-oxidation 1.354637e-2
GO:2000974 negative regulation of pro-B cell differentiation 1.397369e-2
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 1.397369e-2
GO:0006868 glutamine transport 1.397369e-2
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1.397369e-2
GO:0033124 regulation of GTP catabolic process 1.403161e-2
GO:0014066 regulation of phosphatidylinositol 3-kinase cascade 1.404597e-2
GO:0072144 glomerular mesangial cell development 1.422429e-2
GO:0045916 negative regulation of complement activation 1.422429e-2
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1.444165e-2
GO:0034959 endothelin maturation 1.445260e-2
GO:0010816 calcitonin catabolic process 1.445260e-2
GO:0010814 substance P catabolic process 1.445260e-2
GO:0006011 UDP-glucose metabolic process 1.445260e-2
GO:0030431 sleep 1.448750e-2
GO:0050711 negative regulation of interleukin-1 secretion 1.472269e-2
GO:0032674 regulation of interleukin-5 production 1.502956e-2
GO:0060911 cardiac cell fate commitment 1.504993e-2
GO:0071638 negative regulation of monocyte chemotactic protein-1 production 1.505197e-2
GO:0048227 plasma membrane to endosome transport 1.505197e-2
GO:2000469 negative regulation of peroxidase activity 1.505197e-2
GO:2000429 negative regulation of neutrophil aggregation 1.505197e-2
GO:0021528 commissural neuron differentiation in spinal cord 1.505197e-2
GO:0034120 positive regulation of erythrocyte aggregation 1.505197e-2
GO:0035726 common myeloid progenitor cell proliferation 1.505197e-2
GO:0043252 sodium-independent organic anion transport 1.505197e-2
GO:0006556 S-adenosylmethionine biosynthetic process 1.524089e-2
GO:0032108 negative regulation of response to nutrient levels 1.540094e-2
GO:0032479 regulation of type I interferon production 1.552781e-2
GO:0015718 monocarboxylic acid transport 1.557149e-2
GO:0051387 negative regulation of nerve growth factor receptor signaling pathway 1.568112e-2
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 1.568112e-2
GO:0032535 regulation of cellular component size 1.580308e-2
GO:0009083 branched chain family amino acid catabolic process 1.584161e-2
GO:0006306 DNA methylation 1.596443e-2
GO:0048103 somatic stem cell division 1.604358e-2
GO:0050925 negative regulation of negative chemotaxis 1.605158e-2