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Novel motif:21

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name:motif21_TCTTGA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0032501 multicellular organismal process 1.482335e-50
GO:0048739 cardiac muscle fiber development 5.645841e-38
GO:0050896 response to stimulus 1.357165e-37
GO:0009611 response to wounding 7.162540e-34
GO:0030241 skeletal muscle myosin thick filament assembly 3.222029e-33
GO:0032502 developmental process 5.060910e-33
GO:0009888 tissue development 1.617381e-32
GO:0030049 muscle filament sliding 2.625726e-32
GO:0070252 actin-mediated cell contraction 7.265380e-32
GO:0048856 anatomical structure development 7.689115e-32
GO:0042060 wound healing 1.962419e-31
GO:0006950 response to stress 1.017978e-30
GO:0007275 multicellular organismal development 1.104514e-30
GO:0030048 actin filament-based movement 1.903066e-30
GO:0048731 system development 9.782549e-30
GO:0065007 biological regulation 5.888240e-29
GO:0050789 regulation of biological process 6.522777e-29
GO:0065008 regulation of biological quality 2.814580e-28
GO:0051716 cellular response to stimulus 3.799079e-28
GO:0042221 response to chemical stimulus 4.460475e-27
GO:0010035 response to inorganic substance 4.968180e-27
GO:0007599 hemostasis 1.246588e-26
GO:0007596 blood coagulation 1.391294e-26
GO:0050790 regulation of catalytic activity 1.226097e-25
GO:0007076 mitotic chromosome condensation 3.852647e-25
GO:0048513 organ development 7.314743e-25
GO:0006941 striated muscle contraction 7.762315e-25
GO:0048769 sarcomerogenesis 7.841586e-25
GO:0002576 platelet degranulation 1.560080e-24
GO:0007165 signal transduction 1.781432e-24
GO:0050878 regulation of body fluid levels 8.778448e-24
GO:0006936 muscle contraction 1.348147e-23
GO:0016192 vesicle-mediated transport 1.684397e-23
GO:0051179 localization 1.070439e-22
GO:0048747 muscle fiber development 1.114415e-22
GO:0048646 anatomical structure formation involved in morphogenesis 2.960861e-22
GO:0030261 chromosome condensation 6.271419e-22
GO:0051641 cellular localization 6.954203e-22
GO:0007154 cell communication 1.059239e-21
GO:0051234 establishment of localization 1.226671e-21
GO:0003012 muscle system process 1.593751e-21
GO:0007320 insemination 1.858068e-21
GO:0014866 skeletal myofibril assembly 2.158605e-21
GO:0030168 platelet activation 5.759231e-21
GO:0050794 regulation of cellular process 7.902961e-21
GO:0071840 cellular component organization or biogenesis 1.037649e-20
GO:0016043 cellular component organization 3.320539e-20
GO:0023052 signaling 5.849900e-20
GO:0006928 cellular component movement 6.520470e-20
GO:0006810 transport 6.800528e-20
GO:0021509 roof plate formation 7.620749e-20
GO:0065009 regulation of molecular function 9.708318e-20
GO:0072358 cardiovascular system development 3.211032e-19
GO:0007166 cell surface receptor linked signaling pathway 8.914531e-19
GO:0071379 cellular response to prostaglandin stimulus 1.758569e-18
GO:0051592 response to calcium ion 2.123465e-18
GO:0051649 establishment of localization in cell 4.048849e-18
GO:0032940 secretion by cell 4.496965e-18
GO:0045214 sarcomere organization 6.804492e-18
GO:0006887 exocytosis 7.761351e-18
GO:0010038 response to metal ion 1.300608e-17
GO:0055008 cardiac muscle tissue morphogenesis 2.080172e-17
GO:0051704 multi-organism process 3.001185e-17
GO:0048468 cell development 5.186434e-17
GO:0007155 cell adhesion 5.762977e-17
GO:0034383 low-density lipoprotein particle clearance 1.243080e-16
GO:0000070 mitotic sister chromatid segregation 2.951461e-16
GO:0007620 copulation 3.047724e-16
GO:0042159 lipoprotein catabolic process 3.070647e-16
GO:0000819 sister chromatid segregation 3.075952e-16
GO:0071842 cellular component organization at cellular level 5.395066e-16
GO:0030240 skeletal muscle thin filament assembly 5.757230e-16
GO:0010033 response to organic substance 7.370861e-16
GO:0030239 myofibril assembly 1.256569e-15
GO:0048869 cellular developmental process 1.628214e-15
GO:0001775 cell activation 1.962605e-15
GO:0010927 cellular component assembly involved in morphogenesis 1.982800e-15
GO:0071841 cellular component organization or biogenesis at cellular level 2.251644e-15
GO:0030154 cell differentiation 2.348898e-15
GO:0009653 anatomical structure morphogenesis 2.513254e-15
GO:0046903 secretion 3.034244e-15
GO:0060415 muscle tissue morphogenesis 4.082027e-15
GO:0007517 muscle organ development 4.291802e-15
GO:0007507 heart development 4.296037e-15
GO:0010886 positive regulation of cholesterol storage 5.970454e-15
GO:0051239 regulation of multicellular organismal process 9.451360e-15
GO:0048729 tissue morphogenesis 1.309280e-14
GO:0014706 striated muscle tissue development 1.451650e-14
GO:0019220 regulation of phosphate metabolic process 1.552312e-14
GO:0006323 DNA packaging 1.573026e-14
GO:0051915 induction of synaptic plasticity by chemical substance 1.638487e-14
GO:0022607 cellular component assembly 1.758799e-14
GO:0050808 synapse organization 2.922922e-14
GO:0042325 regulation of phosphorylation 3.093374e-14
GO:0032924 activin receptor signaling pathway 3.528193e-14
GO:0009743 response to carbohydrate stimulus 6.323141e-14
GO:0010951 negative regulation of endopeptidase activity 9.163812e-14
GO:0009607 response to biotic stimulus 9.473236e-14
GO:0048853 forebrain morphogenesis 9.819375e-14
GO:0044085 cellular component biogenesis 1.057093e-13
GO:0001932 regulation of protein phosphorylation 1.149158e-13
GO:0007416 synapse assembly 1.170657e-13
GO:0007049 cell cycle 1.178422e-13
GO:0044057 regulation of system process 1.182845e-13
GO:0052547 regulation of peptidase activity 1.219621e-13
GO:0052548 regulation of endopeptidase activity 1.416557e-13
GO:0003008 system process 1.500038e-13
GO:0051707 response to other organism 1.516637e-13
GO:0030029 actin filament-based process 1.646483e-13
GO:0048854 brain morphogenesis 2.255439e-13
GO:0032989 cellular component morphogenesis 2.868887e-13
GO:0071103 DNA conformation change 3.138860e-13
GO:0040011 locomotion 3.540850e-13
GO:0060571 morphogenesis of an epithelial fold 4.128005e-13
GO:0031032 actomyosin structure organization 4.949988e-13
GO:0022612 gland morphogenesis 5.428480e-13
GO:0048519 negative regulation of biological process 6.784569e-13
GO:0000278 mitotic cell cycle 6.876829e-13
GO:0060537 muscle tissue development 7.207309e-13
GO:0001763 morphogenesis of a branching structure 7.492964e-13
GO:0050793 regulation of developmental process 7.648375e-13
GO:0014012 peripheral nervous system axon regeneration 7.767848e-13
GO:0019953 sexual reproduction 8.089440e-13
GO:0071844 cellular component assembly at cellular level 8.094568e-13
GO:0055003 cardiac myofibril assembly 1.017198e-12
GO:0009617 response to bacterium 1.055125e-12
GO:0051336 regulation of hydrolase activity 1.213859e-12
GO:0042953 lipoprotein transport 1.252781e-12
GO:0030010 establishment of cell polarity 1.441598e-12
GO:0031099 regeneration 1.512165e-12
GO:0009987 cellular process 1.715937e-12
GO:0048644 muscle organ morphogenesis 1.779422e-12
GO:0060429 epithelium development 1.981104e-12
GO:0048676 axon extension involved in development 2.092643e-12
GO:0046709 IDP catabolic process 2.495802e-12
GO:0046032 ADP catabolic process 2.495802e-12
GO:0008219 cell death 2.938763e-12
GO:0034097 response to cytokine stimulus 2.960634e-12
GO:0055002 striated muscle cell development 4.030316e-12
GO:0048583 regulation of response to stimulus 4.064013e-12
GO:0055001 muscle cell development 4.295998e-12
GO:0048523 negative regulation of cellular process 5.282320e-12
GO:0002376 immune system process 5.492683e-12
GO:0016265 death 9.225715e-12
GO:0061024 membrane organization 1.770664e-11
GO:0051246 regulation of protein metabolic process 1.780607e-11
GO:0048285 organelle fission 1.852754e-11
GO:0010885 regulation of cholesterol storage 1.975897e-11
GO:0010884 positive regulation of lipid storage 2.143209e-11
GO:0031110 regulation of microtubule polymerization or depolymerization 2.327771e-11
GO:0000087 M phase of mitotic cell cycle 2.366954e-11
GO:0016044 cellular membrane organization 2.468276e-11
GO:0019222 regulation of metabolic process 3.109512e-11
GO:0047497 mitochondrion transport along microtubule 3.538221e-11
GO:0010466 negative regulation of peptidase activity 3.627622e-11
GO:0044255 cellular lipid metabolic process 3.815659e-11
GO:0000003 reproduction 3.836894e-11
GO:0010744 positive regulation of macrophage derived foam cell differentiation 4.611075e-11
GO:0007067 mitosis 4.695056e-11
GO:0045666 positive regulation of neuron differentiation 6.192738e-11
GO:0022414 reproductive process 6.234390e-11
GO:0048738 cardiac muscle tissue development 6.792369e-11
GO:0055013 cardiac muscle cell development 7.163513e-11
GO:2000026 regulation of multicellular organismal development 7.326457e-11
GO:0012501 programmed cell death 7.375292e-11
GO:0032268 regulation of cellular protein metabolic process 7.883722e-11
GO:0031399 regulation of protein modification process 9.282491e-11
GO:0031644 regulation of neurological system process 1.056218e-10
GO:0060389 pathway-restricted SMAD protein phosphorylation 1.095258e-10
GO:0007010 cytoskeleton organization 1.245011e-10
GO:0070482 response to oxygen levels 1.267174e-10
GO:0006642 triglyceride mobilization 1.269433e-10
GO:0019538 protein metabolic process 1.332650e-10
GO:0007186 G-protein coupled receptor protein signaling pathway 1.410986e-10
GO:0035239 tube morphogenesis 1.516452e-10
GO:0051640 organelle localization 1.579531e-10
GO:0040008 regulation of growth 1.606154e-10
GO:0021527 spinal cord association neuron differentiation 2.052634e-10
GO:0007417 central nervous system development 2.078373e-10
GO:0034612 response to tumor necrosis factor 2.105520e-10
GO:0032879 regulation of localization 2.732700e-10
GO:0071356 cellular response to tumor necrosis factor 3.103693e-10
GO:0009605 response to external stimulus 3.258981e-10
GO:0007522 visceral muscle development 3.337636e-10
GO:0051346 negative regulation of hydrolase activity 3.420250e-10
GO:0051654 establishment of mitochondrion localization 3.547034e-10
GO:0007059 chromosome segregation 3.630313e-10
GO:0002237 response to molecule of bacterial origin 3.733464e-10
GO:0030901 midbrain development 3.797108e-10
GO:0018149 peptide cross-linking 3.941493e-10
GO:0034694 response to prostaglandin stimulus 4.177976e-10
GO:0051969 regulation of transmission of nerve impulse 4.206842e-10
GO:0006897 endocytosis 4.223716e-10
GO:0048609 multicellular organismal reproductive process 4.487648e-10
GO:0048518 positive regulation of biological process 4.849282e-10
GO:0022402 cell cycle process 4.955388e-10
GO:0002009 morphogenesis of an epithelium 5.073029e-10
GO:0006629 lipid metabolic process 5.664266e-10
GO:0003007 heart morphogenesis 6.246901e-10
GO:0010876 lipid localization 6.797999e-10
GO:0045540 regulation of cholesterol biosynthetic process 6.951075e-10
GO:0044242 cellular lipid catabolic process 7.110622e-10
GO:0006955 immune response 7.659192e-10
GO:0034381 plasma lipoprotein particle clearance 8.940640e-10
GO:0016337 cell-cell adhesion 1.038934e-9
GO:0006875 cellular metal ion homeostasis 1.306663e-9
GO:0009181 purine ribonucleoside diphosphate catabolic process 1.412861e-9
GO:0001666 response to hypoxia 1.487190e-9
GO:0032496 response to lipopolysaccharide 1.652218e-9
GO:0051971 positive regulation of transmission of nerve impulse 1.681406e-9
GO:0055080 cation homeostasis 1.837811e-9
GO:0007618 mating 2.124625e-9
GO:0031581 hemidesmosome assembly 2.210443e-9
GO:0042327 positive regulation of phosphorylation 2.378538e-9
GO:0022403 cell cycle phase 2.500329e-9
GO:0070555 response to interleukin-1 2.768536e-9
GO:0006952 defense response 2.787505e-9
GO:0071310 cellular response to organic substance 2.813565e-9
GO:0045937 positive regulation of phosphate metabolic process 2.859062e-9
GO:0010269 response to selenium ion 2.956752e-9
GO:0070887 cellular response to chemical stimulus 3.107094e-9
GO:0009566 fertilization 3.155919e-9
GO:0051646 mitochondrion localization 3.347362e-9
GO:0023051 regulation of signaling 3.376784e-9
GO:0009719 response to endogenous stimulus 3.388143e-9
GO:0002027 regulation of heart rate 3.412544e-9
GO:0051240 positive regulation of multicellular organismal process 3.464201e-9
GO:0033036 macromolecule localization 3.547235e-9
GO:0048608 reproductive structure development 3.784644e-9
GO:0055065 metal ion homeostasis 3.821228e-9
GO:0050806 positive regulation of synaptic transmission 4.041403e-9
GO:0006200 ATP catabolic process 4.418895e-9
GO:0034379 very-low-density lipoprotein particle assembly 4.718950e-9
GO:0031175 neuron projection development 5.015029e-9
GO:0030182 neuron differentiation 5.301414e-9
GO:0048878 chemical homeostasis 5.550618e-9
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 5.559109e-9
GO:0031116 positive regulation of microtubule polymerization 5.735935e-9
GO:0007420 brain development 5.777184e-9
GO:0090181 regulation of cholesterol metabolic process 6.073468e-9
GO:0061061 muscle structure development 6.126262e-9
GO:0046503 glycerolipid catabolic process 6.186768e-9
GO:0046464 acylglycerol catabolic process 6.389266e-9
GO:0051293 establishment of spindle localization 6.824088e-9
GO:0006915 apoptosis 6.839722e-9
GO:0019433 triglyceride catabolic process 7.093283e-9
GO:0014912 negative regulation of smooth muscle cell migration 7.290883e-9
GO:0030003 cellular cation homeostasis 7.800461e-9
GO:0048666 neuron development 8.007167e-9
GO:0044248 cellular catabolic process 9.058933e-9
GO:0034374 low-density lipoprotein particle remodeling 9.413901e-9
GO:0070507 regulation of microtubule cytoskeleton organization 9.941357e-9
GO:0007399 nervous system development 1.002751e-8
GO:0044267 cellular protein metabolic process 1.027142e-8
GO:0030036 actin cytoskeleton organization 1.027151e-8
GO:0032787 monocarboxylic acid metabolic process 1.068533e-8
GO:0000302 response to reactive oxygen species 1.139506e-8
GO:0031646 positive regulation of neurological system process 1.169969e-8
GO:0035295 tube development 1.177360e-8
GO:0001841 neural tube formation 1.181834e-8
GO:0061162 establishment of monopolar cell polarity 1.303648e-8
GO:0042904 9-cis-retinoic acid biosynthetic process 1.345844e-8
GO:0009887 organ morphogenesis 1.525621e-8
GO:0030900 forebrain development 1.556629e-8
GO:0051656 establishment of organelle localization 1.647730e-8
GO:0006935 chemotaxis 1.684777e-8
GO:0071396 cellular response to lipid 1.819183e-8
GO:0033993 response to lipid 1.885366e-8
GO:0048662 negative regulation of smooth muscle cell proliferation 1.940424e-8
GO:0001568 blood vessel development 2.005262e-8
GO:0048522 positive regulation of cellular process 2.054908e-8
GO:0048251 elastic fiber assembly 2.089187e-8
GO:0030850 prostate gland development 2.170827e-8
GO:0048732 gland development 2.201935e-8
GO:0015918 sterol transport 2.240871e-8
GO:0007409 axonogenesis 2.484057e-8
GO:0071345 cellular response to cytokine stimulus 2.501035e-8
GO:0031114 regulation of microtubule depolymerization 2.591433e-8
GO:0051960 regulation of nervous system development 2.657516e-8
GO:0010646 regulation of cell communication 2.752016e-8
GO:0046486 glycerolipid metabolic process 2.834729e-8
GO:0031102 neuron projection regeneration 2.852899e-8
GO:0009191 ribonucleoside diphosphate catabolic process 3.113172e-8
GO:0048667 cell morphogenesis involved in neuron differentiation 3.142542e-8
GO:0006464 protein modification process 3.307328e-8
GO:0042632 cholesterol homeostasis 3.478304e-8
GO:0048699 generation of neurons 3.594238e-8
GO:0030030 cell projection organization 3.780282e-8
GO:0007026 negative regulation of microtubule depolymerization 3.905926e-8
GO:0008104 protein localization 3.953972e-8
GO:0042574 retinal metabolic process 4.016694e-8
GO:0031112 positive regulation of microtubule polymerization or depolymerization 4.080750e-8
GO:0030155 regulation of cell adhesion 4.200245e-8
GO:0048812 neuron projection morphogenesis 4.201597e-8
GO:0048262 determination of dorsal/ventral asymmetry 4.322305e-8
GO:0031640 killing of cells of other organism 4.758668e-8
GO:0043623 cellular protein complex assembly 5.367414e-8
GO:0048754 branching morphogenesis of a tube 5.538610e-8
GO:0006662 glycerol ether metabolic process 5.625259e-8
GO:0048858 cell projection morphogenesis 5.861775e-8
GO:0045664 regulation of neuron differentiation 6.371221e-8
GO:0060740 prostate gland epithelium morphogenesis 6.820916e-8
GO:0043085 positive regulation of catalytic activity 6.860554e-8
GO:0040001 establishment of mitotic spindle localization 6.978757e-8
GO:0085029 extracellular matrix assembly 7.138275e-8
GO:0048263 determination of dorsal identity 7.837064e-8
GO:0022002 negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway 7.837064e-8
GO:0000132 establishment of mitotic spindle orientation 7.854126e-8
GO:0018904 organic ether metabolic process 7.932329e-8
GO:0032990 cell part morphogenesis 8.544468e-8
GO:0022008 neurogenesis 8.839130e-8
GO:0009056 catabolic process 8.978296e-8
GO:0035148 tube formation 9.084758e-8
GO:0016042 lipid catabolic process 1.056803e-7
GO:0050804 regulation of synaptic transmission 1.123995e-7
GO:0048514 blood vessel morphogenesis 1.157110e-7
GO:0060638 mesenchymal-epithelial cell signaling 1.157661e-7
GO:0006776 vitamin A metabolic process 1.184859e-7
GO:0015721 bile acid and bile salt transport 1.200389e-7
GO:0006811 ion transport 1.200401e-7
GO:0010743 regulation of macrophage derived foam cell differentiation 1.275347e-7
GO:0046485 ether lipid metabolic process 1.291367e-7
GO:0042592 homeostatic process 1.296436e-7
GO:0003006 developmental process involved in reproduction 1.297978e-7
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 1.322929e-7
GO:0035690 cellular response to drug 1.337467e-7
GO:0032768 regulation of monooxygenase activity 1.412591e-7
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 1.444914e-7
GO:0065003 macromolecular complex assembly 1.457662e-7
GO:0001934 positive regulation of protein phosphorylation 1.508136e-7
GO:0007163 establishment or maintenance of cell polarity 1.520960e-7
GO:0006775 fat-soluble vitamin metabolic process 1.540982e-7
GO:0060512 prostate gland morphogenesis 1.569635e-7
GO:0009725 response to hormone stimulus 1.628200e-7
GO:0072503 cellular divalent inorganic cation homeostasis 1.641421e-7
GO:0071233 cellular response to leucine 1.685452e-7
GO:0010941 regulation of cell death 1.724175e-7
GO:0042493 response to drug 1.800676e-7
GO:0034329 cell junction assembly 1.875444e-7
GO:0030301 cholesterol transport 1.913787e-7
GO:2000836 positive regulation of androgen secretion 1.989017e-7
GO:2000500 positive regulation of induction of apoptosis in response to chemical stimulus 1.989017e-7
GO:0071363 cellular response to growth factor stimulus 2.232353e-7
GO:0042753 positive regulation of circadian rhythm 2.429476e-7
GO:0006996 organelle organization 2.531360e-7
GO:0055009 atrial cardiac muscle tissue morphogenesis 2.659615e-7
GO:0021516 dorsal spinal cord development 2.908263e-7
GO:0001944 vasculature development 2.958245e-7
GO:0032270 positive regulation of cellular protein metabolic process 3.008437e-7
GO:0034377 plasma lipoprotein particle assembly 3.053577e-7
GO:0042362 fat-soluble vitamin biosynthetic process 3.139521e-7
GO:0048167 regulation of synaptic plasticity 3.164728e-7
GO:0072507 divalent inorganic cation homeostasis 3.215383e-7
GO:0071495 cellular response to endogenous stimulus 3.384726e-7
GO:0006916 anti-apoptosis 3.395723e-7
GO:0043549 regulation of kinase activity 3.730582e-7
GO:0050801 ion homeostasis 3.776347e-7
GO:0051657 maintenance of organelle location 3.951319e-7
GO:0042692 muscle cell differentiation 3.990335e-7
GO:0051146 striated muscle cell differentiation 4.064042e-7
GO:0031111 negative regulation of microtubule polymerization or depolymerization 4.149000e-7
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 4.152262e-7
GO:0045663 positive regulation of myoblast differentiation 4.323718e-7
GO:0042180 cellular ketone metabolic process 4.401999e-7
GO:0055007 cardiac muscle cell differentiation 4.515733e-7
GO:0042448 progesterone metabolic process 4.664401e-7
GO:0070848 response to growth factor stimulus 4.829681e-7
GO:0055074 calcium ion homeostasis 4.873978e-7
GO:0008037 cell recognition 4.902922e-7
GO:0051341 regulation of oxidoreductase activity 4.941346e-7
GO:0043412 macromolecule modification 4.958845e-7
GO:0006873 cellular ion homeostasis 5.008167e-7
GO:0034622 cellular macromolecular complex assembly 5.071935e-7
GO:0043933 macromolecular complex subunit organization 5.080969e-7
GO:0031103 axon regeneration 5.205035e-7
GO:0021915 neural tube development 5.237112e-7
GO:0061138 morphogenesis of a branching epithelium 5.293554e-7
GO:0032886 regulation of microtubule-based process 5.326277e-7
GO:0050767 regulation of neurogenesis 5.768560e-7
GO:0055088 lipid homeostasis 5.779804e-7
GO:0006874 cellular calcium ion homeostasis 5.975531e-7
GO:0019725 cellular homeostasis 6.061260e-7
GO:0051338 regulation of transferase activity 6.129438e-7
GO:0006869 lipid transport 6.282454e-7
GO:0030317 sperm motility 6.616104e-7
GO:0048870 cell motility 6.925868e-7
GO:0045926 negative regulation of growth 7.379916e-7
GO:0043067 regulation of programmed cell death 7.530345e-7
GO:0007413 axonal fasciculation 7.607865e-7
GO:0050900 leukocyte migration 8.322869e-7
GO:0006468 protein phosphorylation 8.378253e-7
GO:0055082 cellular chemical homeostasis 9.799257e-7
GO:0044093 positive regulation of molecular function 1.018921e-6
GO:0019752 carboxylic acid metabolic process 1.130063e-6
GO:0035162 embryonic hemopoiesis 1.153336e-6
GO:0007044 cell-substrate junction assembly 1.218264e-6
GO:0009628 response to abiotic stimulus 1.297097e-6
GO:0016477 cell migration 1.320865e-6
GO:0009267 cellular response to starvation 1.323757e-6
GO:0009792 embryo development ending in birth or egg hatching 1.341242e-6
GO:0050999 regulation of nitric-oxide synthase activity 1.424246e-6
GO:0060164 regulation of timing of neuron differentiation 1.427432e-6
GO:0030258 lipid modification 1.431557e-6
GO:0051049 regulation of transport 1.470221e-6
GO:0043086 negative regulation of catalytic activity 1.552010e-6
GO:0031100 organ regeneration 1.556363e-6
GO:0001933 negative regulation of protein phosphorylation 1.561585e-6
GO:0019915 lipid storage 1.563966e-6
GO:0072175 epithelial tube formation 1.635078e-6
GO:0001732 formation of translation initiation complex 1.656568e-6
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1.731446e-6
GO:0030516 regulation of axon extension 1.746602e-6
GO:0051247 positive regulation of protein metabolic process 1.764451e-6
GO:0050701 interleukin-1 secretion 1.810884e-6
GO:0042594 response to starvation 1.886541e-6
GO:0031349 positive regulation of defense response 1.908016e-6
GO:0001558 regulation of cell growth 1.935778e-6
GO:0001838 embryonic epithelial tube formation 1.956502e-6
GO:0007160 cell-matrix adhesion 1.964943e-6
GO:0031953 negative regulation of protein autophosphorylation 2.104556e-6
GO:0045595 regulation of cell differentiation 2.255882e-6
GO:2000534 positive regulation of renal albumin absorption 2.267339e-6
GO:2000481 positive regulation of cAMP-dependent protein kinase activity 2.267339e-6
GO:0070994 detection of oxidative stress 2.267339e-6
GO:2000461 negative regulation of eukaryotic cell surface binding 2.267339e-6
GO:2000478 positive regulation of metanephric glomerular visceral epithelial cell development 2.267339e-6
GO:0000279 M phase 2.284576e-6
GO:0042981 regulation of apoptosis 2.298685e-6
GO:0061387 regulation of extent of cell growth 2.348782e-6
GO:0006909 phagocytosis 2.365572e-6
GO:0007411 axon guidance 2.403581e-6
GO:0031113 regulation of microtubule polymerization 2.412696e-6
GO:0015031 protein transport 2.524856e-6
GO:0051051 negative regulation of transport 2.545199e-6
GO:0048660 regulation of smooth muscle cell proliferation 2.559453e-6
GO:0051659 maintenance of mitochondrion location 2.565126e-6
GO:0000904 cell morphogenesis involved in differentiation 2.718598e-6
GO:0044092 negative regulation of molecular function 2.726228e-6
GO:0051128 regulation of cellular component organization 2.788420e-6
GO:0045785 positive regulation of cell adhesion 2.871771e-6
GO:0009966 regulation of signal transduction 2.881435e-6
GO:0060562 epithelial tube morphogenesis 2.891762e-6
GO:0033554 cellular response to stress 2.994287e-6
GO:0044238 primary metabolic process 3.029412e-6
GO:0000902 cell morphogenesis 3.110020e-6
GO:0006082 organic acid metabolic process 3.137768e-6
GO:0031401 positive regulation of protein modification process 3.158154e-6
GO:0002651 positive regulation of tolerance induction to self antigen 3.175829e-6
GO:0071347 cellular response to interleukin-1 3.241982e-6
GO:0010766 negative regulation of sodium ion transport 3.246219e-6
GO:0048678 response to axon injury 3.295766e-6
GO:0034621 cellular macromolecular complex subunit organization 3.373409e-6
GO:0032387 negative regulation of intracellular transport 3.519569e-6
GO:0048610 cellular process involved in reproduction 3.536149e-6
GO:0040007 growth 3.634281e-6
GO:0009235 cobalamin metabolic process 3.661269e-6
GO:0048496 maintenance of organ identity 3.715190e-6
GO:0048584 positive regulation of response to stimulus 3.866968e-6
GO:0030509 BMP signaling pathway 3.885392e-6
GO:0030521 androgen receptor signaling pathway 4.027741e-6
GO:0045069 regulation of viral genome replication 4.039661e-6
GO:0043201 response to leucine 4.129230e-6
GO:0002709 regulation of T cell mediated immunity 4.164254e-6
GO:0035051 cardiac cell differentiation 4.228821e-6
GO:0044111 development involved in symbiotic interaction 4.309157e-6
GO:0010768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage 4.309157e-6
GO:0019089 transmission of virus 4.309157e-6
GO:0042158 lipoprotein biosynthetic process 4.327311e-6
GO:2000833 positive regulation of steroid hormone secretion 4.402892e-6
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 4.502764e-6
GO:0045859 regulation of protein kinase activity 4.543719e-6
GO:0060442 branching involved in prostate gland morphogenesis 4.558063e-6
GO:0042127 regulation of cell proliferation 4.630726e-6
GO:0016320 endoplasmic reticulum membrane fusion 4.793153e-6
GO:0001578 microtubule bundle formation 4.908863e-6
GO:0008285 negative regulation of cell proliferation 4.997401e-6
GO:0043009 chordate embryonic development 5.065853e-6
GO:0045661 regulation of myoblast differentiation 5.259398e-6
GO:0051046 regulation of secretion 5.412124e-6
GO:0016310 phosphorylation 5.740482e-6
GO:0010883 regulation of lipid storage 5.903755e-6
GO:0009082 branched chain family amino acid biosynthetic process 6.118226e-6
GO:0007584 response to nutrient 6.413125e-6
GO:0072384 organelle transport along microtubule 6.509568e-6
GO:0010647 positive regulation of cell communication 6.716656e-6
GO:0055114 oxidation-reduction process 6.750265e-6
GO:0031341 regulation of cell killing 6.763853e-6
GO:0008360 regulation of cell shape 6.772186e-6
GO:0055072 iron ion homeostasis 6.910957e-6
GO:0023056 positive regulation of signaling 6.933596e-6
GO:0070167 regulation of biomineral tissue development 7.110896e-6
GO:0051129 negative regulation of cellular component organization 7.136136e-6
GO:0006638 neutral lipid metabolic process 7.329091e-6
GO:0030500 regulation of bone mineralization 7.510873e-6
GO:0071822 protein complex subunit organization 7.770863e-6
GO:0032612 interleukin-1 production 7.996379e-6
GO:0031323 regulation of cellular metabolic process 8.158010e-6
GO:0060452 positive regulation of cardiac muscle contraction 8.217751e-6
GO:0006796 phosphate-containing compound metabolic process 8.228557e-6
GO:0006687 glycosphingolipid metabolic process 8.306000e-6


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0021700 developmental maturation 1.363731e-14
GO:0045214 sarcomere organization 2.721375e-13
GO:0019218 regulation of steroid metabolic process 3.393450e-13
GO:0019915 lipid storage 5.549282e-13
GO:0019433 triglyceride catabolic process 1.099995e-12
GO:0046464 acylglycerol catabolic process 5.894727e-12
GO:0019216 regulation of lipid metabolic process 1.132216e-11
GO:0007512 adult heart development 1.275481e-11
GO:0006694 steroid biosynthetic process 2.056911e-11
GO:0048469 cell maturation 3.217952e-11
GO:0007522 visceral muscle development 6.396502e-11
GO:0046503 glycerolipid catabolic process 1.466273e-10
GO:0002740 negative regulation of cytokine secretion involved in immune response 4.914724e-10
GO:0030239 myofibril assembly 5.704284e-10
GO:0002891 positive regulation of immunoglobulin mediated immune response 7.000565e-10
GO:0043434 response to peptide hormone stimulus 9.388717e-10
GO:0045475 locomotor rhythm 2.197460e-9
GO:0045834 positive regulation of lipid metabolic process 2.462949e-9
GO:0010876 lipid localization 2.478452e-9
GO:0002920 regulation of humoral immune response 2.787193e-9
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 3.862149e-9
GO:0046890 regulation of lipid biosynthetic process 4.265404e-9
GO:0007166 cell surface receptor linked signaling pathway 6.507678e-9
GO:0055009 atrial cardiac muscle tissue morphogenesis 8.661335e-9
GO:0050713 negative regulation of interleukin-1 beta secretion 9.212863e-9
GO:0045577 regulation of B cell differentiation 1.593696e-8
GO:0031032 actomyosin structure organization 1.640136e-8
GO:0030049 muscle filament sliding 1.693116e-8
GO:0071827 plasma lipoprotein particle organization 1.727957e-8
GO:0006642 triglyceride mobilization 2.316270e-8
GO:0097006 regulation of plasma lipoprotein particle levels 2.554326e-8
GO:0048739 cardiac muscle fiber development 2.803895e-8
GO:0009725 response to hormone stimulus 3.381006e-8
GO:0042221 response to chemical stimulus 3.637967e-8
GO:0030300 regulation of intestinal cholesterol absorption 4.341613e-8
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 4.584090e-8
GO:0034097 response to cytokine stimulus 4.768477e-8
GO:0007159 leukocyte cell-cell adhesion 5.000540e-8
GO:0030301 cholesterol transport 5.801355e-8
GO:0051915 induction of synaptic plasticity by chemical substance 6.134564e-8
GO:0008202 steroid metabolic process 6.152977e-8
GO:0006810 transport 6.514761e-8
GO:0000302 response to reactive oxygen species 6.687388e-8
GO:0009605 response to external stimulus 8.924885e-8
GO:0055114 oxidation-reduction process 9.427233e-8
GO:0003012 muscle system process 9.865121e-8
GO:0006936 muscle contraction 1.012641e-7
GO:0002922 positive regulation of humoral immune response 1.167732e-7
GO:0010033 response to organic substance 1.476549e-7
GO:0047497 mitochondrion transport along microtubule 1.567685e-7
GO:0051646 mitochondrion localization 1.608474e-7
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 1.616910e-7
GO:0034369 plasma lipoprotein particle remodeling 1.768053e-7
GO:0072091 regulation of stem cell proliferation 1.860178e-7
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 1.882626e-7
GO:0033275 actin-myosin filament sliding 2.449300e-7
GO:0016126 sterol biosynthetic process 2.730618e-7
GO:0070328 triglyceride homeostasis 2.904361e-7
GO:0043056 forward locomotion 3.186668e-7
GO:0046184 aldehyde biosynthetic process 3.452049e-7
GO:0006695 cholesterol biosynthetic process 3.518855e-7
GO:0018206 peptidyl-methionine modification 3.545540e-7
GO:0045940 positive regulation of steroid metabolic process 3.803218e-7
GO:0002861 regulation of inflammatory response to antigenic stimulus 4.046453e-7
GO:0009719 response to endogenous stimulus 4.194066e-7
GO:0033058 directional locomotion 4.195200e-7
GO:0006874 cellular calcium ion homeostasis 4.195332e-7
GO:0050711 negative regulation of interleukin-1 secretion 4.693016e-7
GO:0002889 regulation of immunoglobulin mediated immune response 4.958651e-7
GO:0010873 positive regulation of cholesterol esterification 5.223584e-7
GO:0055088 lipid homeostasis 5.632636e-7
GO:0045588 positive regulation of gamma-delta T cell differentiation 6.291850e-7
GO:0055001 muscle cell development 6.584251e-7
GO:0017196 N-terminal peptidyl-methionine acetylation 6.908766e-7
GO:0051234 establishment of localization 6.987937e-7
GO:0072384 organelle transport along microtubule 6.988373e-7
GO:0055002 striated muscle cell development 7.268780e-7
GO:0065005 protein-lipid complex assembly 9.210144e-7
GO:0006641 triglyceride metabolic process 9.629353e-7
GO:0051179 localization 1.192564e-6
GO:0006869 lipid transport 1.536545e-6
GO:0010872 regulation of cholesterol esterification 1.580468e-6
GO:0042445 hormone metabolic process 1.581965e-6
GO:0006720 isoprenoid metabolic process 1.597262e-6
GO:0006837 serotonin transport 1.601086e-6
GO:0042632 cholesterol homeostasis 1.703396e-6
GO:0051654 establishment of mitochondrion localization 1.781478e-6
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 1.783554e-6
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 1.787829e-6
GO:0031116 positive regulation of microtubule polymerization 1.791275e-6
GO:0002739 regulation of cytokine secretion involved in immune response 1.870543e-6
GO:0034754 cellular hormone metabolic process 1.934354e-6
GO:0006875 cellular metal ion homeostasis 1.941575e-6
GO:0044236 multicellular organismal metabolic process 1.960438e-6
GO:0031112 positive regulation of microtubule polymerization or depolymerization 2.048406e-6
GO:0010269 response to selenium ion 2.048406e-6
GO:0006629 lipid metabolic process 2.294132e-6
GO:0034383 low-density lipoprotein particle clearance 2.320987e-6
GO:0046952 ketone body catabolic process 2.348721e-6
GO:0043462 regulation of ATPase activity 2.459765e-6
GO:0051146 striated muscle cell differentiation 2.468031e-6
GO:0002708 positive regulation of lymphocyte mediated immunity 2.533916e-6
GO:0034374 low-density lipoprotein particle remodeling 2.537533e-6
GO:0072358 cardiovascular system development 2.586833e-6
GO:0051209 release of sequestered calcium ion into cytosol 2.627416e-6
GO:0055074 calcium ion homeostasis 2.980124e-6
GO:0051716 cellular response to stimulus 3.020238e-6
GO:0032501 multicellular organismal process 3.305238e-6
GO:0070537 histone H2A K63-linked deubiquitination 3.369096e-6
GO:0050776 regulation of immune response 3.395104e-6
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 3.626952e-6
GO:0042493 response to drug 3.807267e-6
GO:0010927 cellular component assembly involved in morphogenesis 3.808155e-6
GO:0070252 actin-mediated cell contraction 4.039579e-6
GO:0045471 response to ethanol 4.297128e-6
GO:0048675 axon extension 4.567043e-6
GO:0050709 negative regulation of protein secretion 4.814760e-6
GO:2000648 positive regulation of stem cell proliferation 4.880967e-6
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 4.957918e-6
GO:0006014 D-ribose metabolic process 4.961081e-6
GO:0006952 defense response 5.124253e-6
GO:0002673 regulation of acute inflammatory response 5.974813e-6
GO:0044259 multicellular organismal macromolecule metabolic process 6.153005e-6
GO:0050777 negative regulation of immune response 6.291804e-6
GO:0014848 urinary tract smooth muscle contraction 6.356386e-6
GO:0009887 organ morphogenesis 6.669531e-6
GO:0060402 calcium ion transport into cytosol 6.758197e-6
GO:0051561 elevation of mitochondrial calcium ion concentration 7.379668e-6
GO:0048676 axon extension involved in development 7.558198e-6
GO:0072503 cellular divalent inorganic cation homeostasis 8.554051e-6
GO:0043589 skin morphogenesis 8.664999e-6
GO:0070887 cellular response to chemical stimulus 8.723766e-6
GO:0002026 regulation of the force of heart contraction 9.325152e-6
GO:0055065 metal ion homeostasis 1.014821e-5
GO:0032825 positive regulation of natural killer cell differentiation 1.037482e-5
GO:0006663 platelet activating factor biosynthetic process 1.116800e-5
GO:0008207 C21-steroid hormone metabolic process 1.117768e-5
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 1.120414e-5
GO:0031113 regulation of microtubule polymerization 1.127310e-5
GO:0050710 negative regulation of cytokine secretion 1.325850e-5
GO:0018904 organic ether metabolic process 1.348509e-5
GO:0006950 response to stress 1.357939e-5
GO:0055090 acylglycerol homeostasis 1.464484e-5
GO:0032816 positive regulation of natural killer cell activation 1.487304e-5
GO:0046186 acetaldehyde biosynthetic process 1.521742e-5
GO:0042304 regulation of fatty acid biosynthetic process 1.525836e-5
GO:0019217 regulation of fatty acid metabolic process 1.621384e-5
GO:0050896 response to stimulus 1.672924e-5
GO:0071379 cellular response to prostaglandin stimulus 1.741679e-5
GO:0032101 regulation of response to external stimulus 1.790170e-5
GO:0010897 negative regulation of triglyceride catabolic process 1.796342e-5
GO:0010987 negative regulation of high-density lipoprotein particle clearance 1.796342e-5
GO:0061162 establishment of monopolar cell polarity 1.822934e-5
GO:0051282 regulation of sequestering of calcium ion 1.876175e-5
GO:0050810 regulation of steroid biosynthetic process 1.896854e-5
GO:0002706 regulation of lymphocyte mediated immunity 1.903844e-5
GO:0051480 cytosolic calcium ion homeostasis 1.927394e-5
GO:0008211 glucocorticoid metabolic process 2.018150e-5
GO:0044130 negative regulation of growth of symbiont in host 2.110623e-5
GO:0009052 pentose-phosphate shunt, non-oxidative branch 2.227405e-5
GO:0050778 positive regulation of immune response 2.234690e-5
GO:0060401 cytosolic calcium ion transport 2.235162e-5
GO:0006639 acylglycerol metabolic process 2.259334e-5
GO:0001906 cell killing 2.288739e-5
GO:0016078 tRNA catabolic process 2.396956e-5
GO:0001682 tRNA 5'-leader removal 2.396956e-5
GO:0006739 NADP metabolic process 2.481478e-5
GO:0007204 elevation of cytosolic calcium ion concentration 2.646669e-5
GO:0070508 cholesterol import 2.681855e-5
GO:0071702 organic substance transport 2.687240e-5
GO:0001701 in utero embryonic development 2.852567e-5
GO:0032814 regulation of natural killer cell activation 2.857528e-5
GO:0048513 organ development 2.859147e-5
GO:0010565 regulation of cellular ketone metabolic process 2.871662e-5
GO:0071345 cellular response to cytokine stimulus 2.982711e-5
GO:0008610 lipid biosynthetic process 3.173688e-5
GO:0006979 response to oxidative stress 3.189503e-5
GO:0032963 collagen metabolic process 3.228003e-5
GO:0071310 cellular response to organic substance 3.234611e-5
GO:0045428 regulation of nitric oxide biosynthetic process 3.279124e-5
GO:0007595 lactation 3.375034e-5
GO:0007338 single fertilization 3.436839e-5
GO:0022603 regulation of anatomical structure morphogenesis 3.517447e-5
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 3.540792e-5
GO:0018879 biphenyl metabolic process 3.612659e-5
GO:0003008 system process 3.660946e-5
GO:0050706 regulation of interleukin-1 beta secretion 3.840662e-5
GO:0045932 negative regulation of muscle contraction 3.850542e-5
GO:0065008 regulation of biological quality 3.892063e-5
GO:0045579 positive regulation of B cell differentiation 4.002072e-5
GO:0060082 eye blink reflex 4.173958e-5
GO:0006958 complement activation, classical pathway 4.187102e-5
GO:0030449 regulation of complement activation 4.230950e-5
GO:0006429 leucyl-tRNA aminoacylation 4.329131e-5
GO:0006816 calcium ion transport 4.456313e-5
GO:0045773 positive regulation of axon extension 4.507245e-5
GO:0014832 urinary bladder smooth muscle contraction 4.624842e-5
GO:0008217 regulation of blood pressure 4.701528e-5
GO:0031347 regulation of defense response 4.843843e-5
GO:0090076 relaxation of skeletal muscle 4.907425e-5
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 4.907425e-5
GO:0071902 positive regulation of protein serine/threonine kinase activity 4.970666e-5
GO:0009888 tissue development 5.040385e-5
GO:0006278 RNA-dependent DNA replication 5.090554e-5
GO:0019693 ribose phosphate metabolic process 5.244971e-5
GO:0010896 regulation of triglyceride catabolic process 5.387599e-5
GO:0009611 response to wounding 5.407102e-5
GO:0002703 regulation of leukocyte mediated immunity 5.411804e-5
GO:0002697 regulation of immune effector process 5.456300e-5
GO:0010744 positive regulation of macrophage derived foam cell differentiation 5.481304e-5
GO:0072507 divalent inorganic cation homeostasis 5.604681e-5
GO:0071495 cellular response to endogenous stimulus 5.933726e-5
GO:0009612 response to mechanical stimulus 5.947057e-5
GO:0045721 negative regulation of gluconeogenesis 6.009399e-5
GO:0042984 regulation of amyloid precursor protein biosynthetic process 6.076702e-5
GO:0031667 response to nutrient levels 6.190513e-5
GO:0010677 negative regulation of cellular carbohydrate metabolic process 6.542536e-5
GO:0002874 regulation of chronic inflammatory response to antigenic stimulus 6.548511e-5
GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly 6.648163e-5
GO:0006721 terpenoid metabolic process 6.686055e-5
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 6.763878e-5
GO:0051239 regulation of multicellular organismal process 6.790000e-5
GO:0006069 ethanol oxidation 6.815508e-5
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 6.815508e-5
GO:0048588 developmental cell growth 6.909721e-5
GO:0030540 female genitalia development 6.914753e-5
GO:0006638 neutral lipid metabolic process 7.094798e-5
GO:0050673 epithelial cell proliferation 7.241070e-5
GO:0009991 response to extracellular stimulus 7.365757e-5
GO:0090201 negative regulation of release of cytochrome c from mitochondria 7.739663e-5
GO:0042159 lipoprotein catabolic process 7.959881e-5
GO:0031349 positive regulation of defense response 8.048792e-5
GO:0032103 positive regulation of response to external stimulus 8.179530e-5
GO:0043255 regulation of carbohydrate biosynthetic process 8.287836e-5
GO:0006117 acetaldehyde metabolic process 8.515217e-5
GO:0032962 positive regulation of inositol trisphosphate biosynthetic process 8.515217e-5
GO:0050707 regulation of cytokine secretion 8.707301e-5
GO:0042474 middle ear morphogenesis 8.738239e-5
GO:0019370 leukotriene biosynthetic process 8.752216e-5
GO:0090075 relaxation of muscle 8.759076e-5
GO:0048304 positive regulation of isotype switching to IgG isotypes 8.859025e-5
GO:0001820 serotonin secretion 9.014034e-5
GO:0002027 regulation of heart rate 9.232988e-5
GO:0002455 humoral immune response mediated by circulating immunoglobulin 9.607189e-5
GO:0042692 muscle cell differentiation 9.626462e-5
GO:0006066 alcohol metabolic process 9.690109e-5
GO:0032691 negative regulation of interleukin-1 beta production 9.821483e-5
GO:0010743 regulation of macrophage derived foam cell differentiation 9.865399e-5
GO:0050727 regulation of inflammatory response 9.869732e-5
GO:0048302 regulation of isotype switching to IgG isotypes 1.022294e-4
GO:0031214 biomineral tissue development 1.027047e-4
GO:0045833 negative regulation of lipid metabolic process 1.033088e-4
GO:0002820 negative regulation of adaptive immune response 1.033719e-4
GO:0046640 regulation of alpha-beta T cell proliferation 1.036030e-4
GO:0007229 integrin-mediated signaling pathway 1.079803e-4
GO:0002707 negative regulation of lymphocyte mediated immunity 1.104380e-4
GO:0010232 vascular transport 1.105949e-4
GO:0090162 establishment of epithelial cell polarity 1.145102e-4
GO:0045540 regulation of cholesterol biosynthetic process 1.165424e-4
GO:0033700 phospholipid efflux 1.165424e-4
GO:0030325 adrenal gland development 1.178265e-4
GO:0034392 negative regulation of smooth muscle cell apoptosis 1.203940e-4
GO:0002227 innate immune response in mucosa 1.203940e-4
GO:0001523 retinoid metabolic process 1.224680e-4
GO:0070995 NADPH oxidation 1.230121e-4
GO:0009790 embryo development 1.257921e-4
GO:0034381 plasma lipoprotein particle clearance 1.275677e-4
GO:0046456 icosanoid biosynthetic process 1.296955e-4
GO:0006690 icosanoid metabolic process 1.308994e-4
GO:0007155 cell adhesion 1.325131e-4
GO:0001910 regulation of leukocyte mediated cytotoxicity 1.332060e-4
GO:0045595 regulation of cell differentiation 1.343225e-4
GO:0051224 negative regulation of protein transport 1.376827e-4
GO:0034612 response to tumor necrosis factor 1.392247e-4
GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific 1.433700e-4
GO:0009236 cobalamin biosynthetic process 1.433700e-4
GO:0055013 cardiac muscle cell development 1.465930e-4
GO:0050729 positive regulation of inflammatory response 1.482268e-4
GO:0010975 regulation of neuron projection development 1.484231e-4
GO:0050704 regulation of interleukin-1 secretion 1.495552e-4
GO:0034505 tooth mineralization 1.503379e-4
GO:0001676 long-chain fatty acid metabolic process 1.567103e-4
GO:0090209 negative regulation of triglyceride metabolic process 1.569489e-4
GO:0010823 negative regulation of mitochondrion organization 1.569489e-4
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1.592674e-4
GO:0001969 regulation of activation of membrane attack complex 1.593289e-4
GO:0007584 response to nutrient 1.600189e-4
GO:0031953 negative regulation of protein autophosphorylation 1.630125e-4
GO:0002253 activation of immune response 1.634046e-4
GO:0018963 phthalate metabolic process 1.644018e-4
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.657217e-4
GO:0033344 cholesterol efflux 1.661194e-4
GO:0044281 small molecule metabolic process 1.684745e-4
GO:0014012 peripheral nervous system axon regeneration 1.696930e-4
GO:0060621 negative regulation of cholesterol import 1.713399e-4
GO:0007210 serotonin receptor signaling pathway 1.713399e-4
GO:0022610 biological adhesion 1.718266e-4
GO:0010817 regulation of hormone levels 1.745452e-4
GO:0006398 histone mRNA 3'-end processing 1.801497e-4
GO:0051241 negative regulation of multicellular organismal process 1.805200e-4
GO:0031342 negative regulation of cell killing 1.812058e-4
GO:0007026 negative regulation of microtubule depolymerization 1.814242e-4
GO:0060620 regulation of cholesterol import 1.855031e-4
GO:0090181 regulation of cholesterol metabolic process 1.865552e-4
GO:0010828 positive regulation of glucose transport 1.902874e-4
GO:0006776 vitamin A metabolic process 1.964510e-4
GO:0042953 lipoprotein transport 1.975027e-4
GO:0031341 regulation of cell killing 2.001265e-4
GO:0051004 regulation of lipoprotein lipase activity 2.006332e-4
GO:0044057 regulation of system process 2.031215e-4
GO:0006068 ethanol catabolic process 2.036686e-4
GO:0048646 anatomical structure formation involved in morphogenesis 2.054454e-4
GO:0009653 anatomical structure morphogenesis 2.058102e-4
GO:0042446 hormone biosynthetic process 2.123004e-4
GO:0030307 positive regulation of cell growth 2.131393e-4
GO:2001021 negative regulation of response to DNA damage stimulus 2.184060e-4
GO:0019321 pentose metabolic process 2.211682e-4
GO:0071354 cellular response to interleukin-6 2.364757e-4
GO:0071375 cellular response to peptide hormone stimulus 2.374247e-4
GO:0034377 plasma lipoprotein particle assembly 2.389006e-4
GO:0060537 muscle tissue development 2.406915e-4
GO:0032387 negative regulation of intracellular transport 2.487134e-4
GO:0016125 sterol metabolic process 2.589431e-4
GO:0032787 monocarboxylic acid metabolic process 2.595574e-4
GO:0045923 positive regulation of fatty acid metabolic process 2.600471e-4
GO:0044255 cellular lipid metabolic process 2.607161e-4
GO:0034113 heterotypic cell-cell adhesion 2.634963e-4
GO:0016337 cell-cell adhesion 2.659069e-4
GO:0014706 striated muscle tissue development 2.728688e-4
GO:0007600 sensory perception 2.775284e-4
GO:0044058 regulation of digestive system process 2.786743e-4
GO:0010821 regulation of mitochondrion organization 2.833130e-4
GO:0060557 positive regulation of vitamin D biosynthetic process 2.840962e-4
GO:0044205 'de novo' UMP biosynthetic process 2.840962e-4
GO:0042537 benzene-containing compound metabolic process 2.935898e-4
GO:0048240 sperm capacitation 3.018149e-4
GO:0032350 regulation of hormone metabolic process 3.037717e-4
GO:0007589 body fluid secretion 3.048822e-4
GO:0043406 positive regulation of MAP kinase activity 3.059409e-4
GO:0048545 response to steroid hormone stimulus 3.118026e-4
GO:0043901 negative regulation of multi-organism process 3.132762e-4
GO:0002921 negative regulation of humoral immune response 3.146372e-4
GO:0007186 G-protein coupled receptor protein signaling pathway 3.155468e-4
GO:0006691 leukotriene metabolic process 3.173012e-4
GO:0043486 histone exchange 3.197947e-4
GO:0050864 regulation of B cell activation 3.261347e-4
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 3.344904e-4
GO:0060788 ectodermal placode formation 3.367915e-4
GO:0050994 regulation of lipid catabolic process 3.394052e-4
GO:0045840 positive regulation of mitosis 3.396896e-4
GO:0010982 regulation of high-density lipoprotein particle clearance 3.399740e-4
GO:0031647 regulation of protein stability 3.424506e-4
GO:0034372 very-low-density lipoprotein particle remodeling 3.444531e-4
GO:0032692 negative regulation of interleukin-1 production 3.496877e-4
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 3.507258e-4
GO:0019221 cytokine-mediated signaling pathway 3.514243e-4
GO:0010885 regulation of cholesterol storage 3.564170e-4
GO:0001101 response to acid 3.655430e-4
GO:0008203 cholesterol metabolic process 3.660594e-4
GO:0031114 regulation of microtubule depolymerization 3.697443e-4
GO:0010035 response to inorganic substance 3.781214e-4
GO:0046950 cellular ketone body metabolic process 3.781725e-4
GO:0016101 diterpenoid metabolic process 3.796569e-4
GO:0006636 unsaturated fatty acid biosynthetic process 3.858420e-4
GO:0070509 calcium ion import 3.894723e-4
GO:0071396 cellular response to lipid 3.906731e-4
GO:0043112 receptor metabolic process 3.932787e-4
GO:0034509 centromeric core chromatin assembly 3.940287e-4
GO:0034080 CenH3-containing nucleosome assembly at centromere 3.940287e-4
GO:0006662 glycerol ether metabolic process 4.012816e-4
GO:0032488 Cdc42 protein signal transduction 4.051711e-4
GO:0048671 negative regulation of collateral sprouting 4.077391e-4
GO:0006927 transformed cell apoptosis 4.077391e-4
GO:0090199 regulation of release of cytochrome c from mitochondria 4.113195e-4
GO:0010827 regulation of glucose transport 4.133728e-4
GO:0045445 myoblast differentiation 4.181900e-4
GO:0044092 negative regulation of molecular function 4.228100e-4
GO:0006982 response to lipid hydroperoxide 4.290978e-4
GO:0001915 negative regulation of T cell mediated cytotoxicity 4.302923e-4
GO:0050853 B cell receptor signaling pathway 4.380135e-4
GO:0006775 fat-soluble vitamin metabolic process 4.394834e-4
GO:0017085 response to insecticide 4.398369e-4
GO:0060766 negative regulation of androgen receptor signaling pathway 4.404069e-4
GO:0040011 locomotion 4.428924e-4
GO:0003163 sinoatrial node development 4.503155e-4
GO:0002684 positive regulation of immune system process 4.584785e-4
GO:0033143 regulation of steroid hormone receptor signaling pathway 4.636428e-4
GO:0006491 N-glycan processing 4.795683e-4
GO:0048512 circadian behavior 4.867726e-4
GO:0015761 mannose transport 4.903209e-4
GO:0055010 ventricular cardiac muscle tissue morphogenesis 4.968232e-4
GO:0043129 surfactant homeostasis 4.976704e-4
GO:0046889 positive regulation of lipid biosynthetic process 5.042427e-4
GO:0016042 lipid catabolic process 5.065035e-4
GO:0031343 positive regulation of cell killing 5.191926e-4
GO:0006067 ethanol metabolic process 5.203320e-4
GO:0032800 receptor biosynthetic process 5.273883e-4
GO:0001933 negative regulation of protein phosphorylation 5.279215e-4
GO:0043086 negative regulation of catalytic activity 5.375115e-4
GO:0046541 saliva secretion 5.409101e-4
GO:0045019 negative regulation of nitric oxide biosynthetic process 5.495786e-4
GO:0030003 cellular cation homeostasis 5.717984e-4
GO:0006103 2-oxoglutarate metabolic process 5.725495e-4
GO:0060765 regulation of androgen receptor signaling pathway 6.002505e-4
GO:0010886 positive regulation of cholesterol storage 6.034068e-4
GO:0000303 response to superoxide 6.072538e-4
GO:0045069 regulation of viral genome replication 6.076561e-4
GO:0048732 gland development 6.249143e-4
GO:0006081 cellular aldehyde metabolic process 6.258873e-4
GO:0001960 negative regulation of cytokine-mediated signaling pathway 6.337940e-4
GO:0070371 ERK1 and ERK2 cascade 6.394349e-4
GO:0009100 glycoprotein metabolic process 6.526792e-4
GO:0006954 inflammatory response 6.578471e-4
GO:0010989 negative regulation of low-density lipoprotein particle clearance 6.609176e-4
GO:0030261 chromosome condensation 6.710318e-4
GO:0014014 negative regulation of gliogenesis 6.731410e-4
GO:0034380 high-density lipoprotein particle assembly 6.740894e-4
GO:0030323 respiratory tube development 6.861178e-4
GO:0071295 cellular response to vitamin 6.872160e-4
GO:0045994 positive regulation of translational initiation by iron 6.974433e-4
GO:0061048 negative regulation of branching involved in lung morphogenesis 6.974433e-4
GO:0034116 positive regulation of heterotypic cell-cell adhesion 6.974433e-4
GO:0010519 negative regulation of phospholipase activity 6.974433e-4
GO:0002037 negative regulation of L-glutamate transport 6.974433e-4
GO:0006545 glycine biosynthetic process 6.974433e-4
GO:0060214 endocardium formation 7.036965e-4
GO:0001909 leukocyte mediated cytotoxicity 7.066284e-4
GO:0021941 negative regulation of cerebellar granule cell precursor proliferation 7.272114e-4
GO:0009101 glycoprotein biosynthetic process 7.377845e-4
GO:0055006 cardiac cell development 7.402939e-4
GO:0001798 positive regulation of type IIa hypersensitivity 7.555877e-4
GO:0018894 dibenzo-p-dioxin metabolic process 7.555877e-4
GO:0001788 antibody-dependent cellular cytotoxicity 7.641651e-4
GO:0060426 lung vasculature development 7.651725e-4
GO:0061387 regulation of extent of cell growth 7.652308e-4
GO:0032469 endoplasmic reticulum calcium ion homeostasis 7.662842e-4
GO:0051005 negative regulation of lipoprotein lipase activity 7.682503e-4
GO:0045087 innate immune response 7.772271e-4
GO:0045723 positive regulation of fatty acid biosynthetic process 7.796890e-4
GO:0030324 lung development 7.857074e-4
GO:0043648 dicarboxylic acid metabolic process 7.881243e-4
GO:0071356 cellular response to tumor necrosis factor 7.920947e-4
GO:0009115 xanthine catabolic process 7.924778e-4
GO:0072376 protein activation cascade 7.965593e-4
GO:0060541 respiratory system development 8.081647e-4
GO:0033273 response to vitamin 8.188876e-4
GO:0021933 radial glia guided migration of cerebellar granule cell 8.314700e-4
GO:0006700 C21-steroid hormone biosynthetic process 8.328351e-4
GO:0071229 cellular response to acid 8.455691e-4
GO:0007507 heart development 8.592260e-4
GO:0071418 cellular response to amine stimulus 8.889301e-4
GO:0002699 positive regulation of immune effector process 9.015982e-4
GO:0030010 establishment of cell polarity 9.228192e-4
GO:0051249 regulation of lymphocyte activation 9.269273e-4
GO:0051260 protein homooligomerization 9.276034e-4
GO:0048738 cardiac muscle tissue development 9.287850e-4
GO:0048670 regulation of collateral sprouting 9.295107e-4
GO:0048712 negative regulation of astrocyte differentiation 9.389715e-4
GO:0031344 regulation of cell projection organization 9.407783e-4
GO:0071803 positive regulation of podosome assembly 9.450124e-4
GO:0032780 negative regulation of ATPase activity 9.450124e-4
GO:0051055 negative regulation of lipid biosynthetic process 9.458980e-4
GO:0080134 regulation of response to stress 9.459279e-4
GO:0060059 embryonic retina morphogenesis in camera-type eye 9.716518e-4
GO:0048856 anatomical structure development 9.812751e-4
GO:0032964 collagen biosynthetic process 9.832468e-4
GO:0031576 G2/M transition checkpoint 1.001307e-3
GO:0031915 positive regulation of synaptic plasticity 1.024202e-3
GO:0009112 nucleobase metabolic process 1.031990e-3
GO:0050854 regulation of antigen receptor-mediated signaling pathway 1.032316e-3
GO:0008299 isoprenoid biosynthetic process 1.038336e-3
GO:0048747 muscle fiber development 1.040465e-3
GO:0051347 positive regulation of transferase activity 1.041827e-3
GO:0002682 regulation of immune system process 1.045117e-3
GO:0007622 rhythmic behavior 1.059070e-3
GO:0009566 fertilization 1.073317e-3
GO:0048584 positive regulation of response to stimulus 1.075023e-3
GO:0002329 pre-B cell differentiation 1.095492e-3
GO:0003230 cardiac atrium development 1.106236e-3
GO:0001957 intramembranous ossification 1.118145e-3
GO:0060073 micturition 1.121108e-3
GO:0001869 negative regulation of complement activation, lectin pathway 1.129497e-3
GO:0070836 caveola assembly 1.129497e-3
GO:0071417 cellular response to organic nitrogen 1.130867e-3
GO:0032870 cellular response to hormone stimulus 1.149592e-3
GO:0016973 poly(A)+ mRNA export from nucleus 1.151989e-3
GO:0046641 positive regulation of alpha-beta T cell proliferation 1.154088e-3
GO:0061031 endodermal digestive tract morphogenesis 1.173764e-3
GO:0009792 embryo development ending in birth or egg hatching 1.179679e-3
GO:0046903 secretion 1.203267e-3
GO:0046219 indolalkylamine biosynthetic process 1.210265e-3
GO:0045916 negative regulation of complement activation 1.210265e-3
GO:0042427 serotonin biosynthetic process 1.210265e-3
GO:0034370 triglyceride-rich lipoprotein particle remodeling 1.218123e-3
GO:0046449 creatinine metabolic process 1.243356e-3
GO:0051591 response to cAMP 1.258379e-3
GO:0070365 hepatocyte differentiation 1.260444e-3
GO:0003013 circulatory system process 1.265356e-3
GO:0070838 divalent metal ion transport 1.265586e-3
GO:0045597 positive regulation of cell differentiation 1.277729e-3