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Novel motif:22

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name:motif22_GGMCTG

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0010624 regulation of Schwann cell proliferation 1.168538e-15
GO:0042506 tyrosine phosphorylation of Stat5 protein 1.640923e-12
GO:0010625 positive regulation of Schwann cell proliferation 1.848607e-11
GO:0010288 response to lead ion 3.914670e-11
GO:0008078 mesodermal cell migration 5.937741e-11
GO:0042503 tyrosine phosphorylation of Stat3 protein 8.227879e-11
GO:0031440 regulation of mRNA 3'-end processing 8.826510e-11
GO:0010506 regulation of autophagy 2.336041e-10
GO:0061014 positive regulation of mRNA catabolic process 2.792945e-10
GO:0015879 carnitine transport 3.152432e-10
GO:0031442 positive regulation of mRNA 3'-end processing 4.578571e-10
GO:0007296 vitellogenesis 3.319176e-9
GO:0060337 type I interferon-mediated signaling pathway 3.371575e-9
GO:0035814 negative regulation of renal sodium excretion 4.640483e-9
GO:0032863 activation of Rac GTPase activity 5.403364e-9
GO:0000413 protein peptidyl-prolyl isomerization 6.192350e-9
GO:0034340 response to type I interferon 7.039940e-9
GO:0043503 skeletal muscle fiber adaptation 7.652424e-9
GO:0071732 cellular response to nitric oxide 7.827064e-9
GO:0030037 actin filament reorganization involved in cell cycle 8.283362e-9
GO:0035966 response to topologically incorrect protein 8.869105e-9
GO:0006544 glycine metabolic process 1.562699e-8
GO:0035313 wound healing, spreading of epidermal cells 1.663216e-8
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 3.060716e-8
GO:0045112 integrin biosynthetic process 3.466641e-8
GO:0061383 trabecula morphogenesis 4.328632e-8
GO:0006457 protein folding 4.737104e-8
GO:0015936 coenzyme A metabolic process 7.084570e-8
GO:0090241 negative regulation of histone H4 acetylation 8.242388e-8
GO:0060343 trabecula formation 1.000078e-7
GO:0034505 tooth mineralization 1.021895e-7
GO:0022009 central nervous system vasculogenesis 1.455284e-7
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 1.586690e-7
GO:0043206 fibril organization 1.627445e-7
GO:0048242 epinephrine secretion 1.702808e-7
GO:0015939 pantothenate metabolic process 1.789727e-7
GO:0043585 nose morphogenesis 1.792528e-7
GO:0006853 carnitine shuttle 2.032253e-7
GO:0002528 regulation of vascular permeability involved in acute inflammatory response 2.118505e-7
GO:0035854 eosinophil fate commitment 2.159974e-7
GO:0030222 eosinophil differentiation 2.159974e-7
GO:0042891 antibiotic transport 2.221395e-7
GO:0031330 negative regulation of cellular catabolic process 2.413613e-7
GO:0043088 regulation of Cdc42 GTPase activity 2.435893e-7
GO:0044319 wound healing, spreading of cells 2.613213e-7
GO:0070483 detection of hypoxia 2.715774e-7
GO:0042508 tyrosine phosphorylation of Stat1 protein 2.896212e-7
GO:0072321 chaperone-mediated protein transport 3.480324e-7
GO:0050779 RNA destabilization 4.340953e-7
GO:0006986 response to unfolded protein 4.588974e-7
GO:0031329 regulation of cellular catabolic process 4.991576e-7
GO:0031282 regulation of guanylate cyclase activity 6.393152e-7
GO:0055026 negative regulation of cardiac muscle tissue development 7.087665e-7
GO:0043462 regulation of ATPase activity 7.381566e-7
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 7.639251e-7
GO:0018208 peptidyl-proline modification 7.978315e-7
GO:0050685 positive regulation of mRNA processing 8.220144e-7
GO:0007006 mitochondrial membrane organization 9.212261e-7
GO:0071731 response to nitric oxide 9.657666e-7
GO:0090084 negative regulation of inclusion body assembly 1.305575e-6
GO:0010626 negative regulation of Schwann cell proliferation 1.336166e-6
GO:0032956 regulation of actin cytoskeleton organization 1.351129e-6
GO:0019221 cytokine-mediated signaling pathway 1.513655e-6
GO:0070715 sodium-dependent organic cation transport 1.530507e-6
GO:0060731 positive regulation of intestinal epithelial structure maintenance 1.530507e-6
GO:0052106 quorum sensing involved in interaction with host 1.530507e-6
GO:0051029 rRNA transport 1.602987e-6
GO:0007028 cytoplasm organization 1.646372e-6
GO:0010896 regulation of triglyceride catabolic process 1.667964e-6
GO:0060346 bone trabecula formation 1.675805e-6
GO:0031064 negative regulation of histone deacetylation 1.680799e-6
GO:0043089 positive regulation of Cdc42 GTPase activity 1.740082e-6
GO:0032862 activation of Rho GTPase activity 1.885477e-6
GO:0032970 regulation of actin filament-based process 1.939425e-6
GO:0007509 mesoderm migration involved in gastrulation 2.024079e-6
GO:0045039 protein import into mitochondrial inner membrane 2.071387e-6
GO:0032312 regulation of ARF GTPase activity 2.096380e-6
GO:0060251 regulation of glial cell proliferation 2.372717e-6
GO:0060730 regulation of intestinal epithelial structure maintenance 2.566361e-6
GO:0060491 regulation of cell projection assembly 2.639300e-6
GO:0032926 negative regulation of activin receptor signaling pathway 2.845236e-6
GO:0061028 establishment of endothelial barrier 3.168811e-6
GO:0010310 regulation of hydrogen peroxide metabolic process 3.218148e-6
GO:0043314 negative regulation of neutrophil degranulation 3.272169e-6
GO:0014044 Schwann cell development 3.291736e-6
GO:0071276 cellular response to cadmium ion 3.456199e-6
GO:0048708 astrocyte differentiation 3.815132e-6
GO:0007021 tubulin complex assembly 3.992095e-6
GO:0060351 cartilage development involved in endochondral bone morphogenesis 4.234144e-6
GO:0006545 glycine biosynthetic process 4.413051e-6
GO:0006984 ER-nucleus signaling pathway 5.205506e-6
GO:0002886 regulation of myeloid leukocyte mediated immunity 5.733114e-6
GO:0008624 induction of apoptosis by extracellular signals 6.283515e-6
GO:0002098 tRNA wobble uridine modification 6.486772e-6
GO:0072488 ammonium transmembrane transport 6.486772e-6
GO:0034227 tRNA thio-modification 6.486772e-6
GO:0044342 type B pancreatic cell proliferation 6.518774e-6
GO:0010918 positive regulation of mitochondrial membrane potential 6.518774e-6
GO:0001892 embryonic placenta development 6.981705e-6
GO:0070345 negative regulation of fat cell proliferation 7.095139e-6
GO:0043249 erythrocyte maturation 7.193554e-6
GO:0033209 tumor necrosis factor-mediated signaling pathway 7.318818e-6
GO:0007007 inner mitochondrial membrane organization 7.445866e-6
GO:0032231 regulation of actin filament bundle assembly 7.626617e-6
GO:0046320 regulation of fatty acid oxidation 8.399849e-6
GO:0071260 cellular response to mechanical stimulus 9.878524e-6
GO:2000249 regulation of actin cytoskeleton reorganization 9.907314e-6
GO:0046655 folic acid metabolic process 1.030253e-5
GO:0090130 tissue migration 1.035144e-5
GO:0051016 barbed-end actin filament capping 1.098475e-5
GO:0060020 Bergmann glial cell differentiation 1.220371e-5
GO:0006646 phosphatidylethanolamine biosynthetic process 1.228074e-5
GO:0032374 regulation of cholesterol transport 1.313781e-5
GO:0043300 regulation of leukocyte degranulation 1.323698e-5
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 1.368694e-5
GO:0046724 oxalic acid secretion 1.368694e-5
GO:0031284 positive regulation of guanylate cyclase activity 1.392541e-5
GO:0015937 coenzyme A biosynthetic process 1.435073e-5
GO:0032720 negative regulation of tumor necrosis factor production 1.476549e-5
GO:0070498 interleukin-1-mediated signaling pathway 1.564316e-5
GO:0045415 negative regulation of interleukin-8 biosynthetic process 1.577719e-5
GO:0045085 negative regulation of interleukin-2 biosynthetic process 1.578959e-5
GO:0022011 myelination in peripheral nervous system 1.631483e-5
GO:0043313 regulation of neutrophil degranulation 1.916785e-5
GO:0045351 type I interferon biosynthetic process 1.945979e-5
GO:0046626 regulation of insulin receptor signaling pathway 2.014761e-5
GO:0033505 floor plate morphogenesis 2.051758e-5
GO:0014002 astrocyte development 2.106509e-5
GO:0043467 regulation of generation of precursor metabolites and energy 2.160594e-5
GO:0032232 negative regulation of actin filament bundle assembly 2.287693e-5
GO:0046325 negative regulation of glucose import 2.392421e-5
GO:0006914 autophagy 2.531855e-5
GO:0022617 extracellular matrix disassembly 2.623461e-5
GO:0090083 regulation of inclusion body assembly 3.289205e-5
GO:0014037 Schwann cell differentiation 3.322127e-5
GO:0035928 rRNA import into mitochondrion 3.392223e-5
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 3.443420e-5
GO:0061013 regulation of mRNA catabolic process 3.670788e-5
GO:0019264 glycine biosynthetic process from serine 3.727769e-5
GO:0007141 male meiosis I 3.775672e-5
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 3.789506e-5
GO:0002017 regulation of blood volume by renal aldosterone 3.794845e-5
GO:0048261 negative regulation of receptor-mediated endocytosis 4.201725e-5
GO:0090239 regulation of histone H4 acetylation 4.326096e-5
GO:0032964 collagen biosynthetic process 4.486250e-5
GO:0060338 regulation of type I interferon-mediated signaling pathway 4.691658e-5
GO:0010874 regulation of cholesterol efflux 4.812787e-5
GO:0060620 regulation of cholesterol import 4.839586e-5
GO:0042117 monocyte activation 4.862268e-5
GO:0051580 regulation of neurotransmitter uptake 4.993997e-5
GO:0009650 UV protection 5.284441e-5
GO:0060311 negative regulation of elastin catabolic process 5.377340e-5
GO:0060313 negative regulation of blood vessel remodeling 5.377340e-5
GO:0010711 negative regulation of collagen catabolic process 5.377340e-5
GO:0010703 negative regulation of histolysis 5.377340e-5
GO:0051492 regulation of stress fiber assembly 5.393424e-5
GO:0032474 otolith morphogenesis 5.463539e-5
GO:0048382 mesendoderm development 5.581481e-5
GO:0048144 fibroblast proliferation 6.083634e-5
GO:0033159 negative regulation of protein import into nucleus, translocation 6.083634e-5
GO:0001880 Mullerian duct regression 6.083634e-5
GO:0030433 ER-associated protein catabolic process 6.114759e-5
GO:0032855 positive regulation of Rac GTPase activity 6.651104e-5
GO:0033239 negative regulation of cellular amine metabolic process 6.760143e-5
GO:0032929 negative regulation of superoxide anion generation 6.760143e-5
GO:0018879 biphenyl metabolic process 6.905407e-5
GO:0045806 negative regulation of endocytosis 7.093415e-5
GO:0009070 serine family amino acid biosynthetic process 7.205976e-5
GO:0045940 positive regulation of steroid metabolic process 7.221106e-5
GO:0048241 epinephrine transport 7.420523e-5
GO:0016236 macroautophagy 7.471402e-5
GO:0006956 complement activation 7.604627e-5
GO:0010987 negative regulation of high-density lipoprotein particle clearance 8.299403e-5
GO:0010897 negative regulation of triglyceride catabolic process 8.299403e-5
GO:0006526 arginine biosynthetic process 8.299403e-5
GO:0033197 response to vitamin E 8.726121e-5
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 8.839650e-5
GO:0072061 inner medullary collecting duct development 9.624193e-5
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 9.624193e-5
GO:0072060 outer medullary collecting duct development 9.624193e-5
GO:0007635 chemosensory behavior 1.014044e-4
GO:0051005 negative regulation of lipoprotein lipase activity 1.027498e-4
GO:2000465 regulation of glycogen (starch) synthase activity 1.050613e-4
GO:0044062 regulation of excretion 1.109771e-4
GO:0007260 tyrosine phosphorylation of STAT protein 1.115814e-4
GO:0009894 regulation of catabolic process 1.219951e-4
GO:0015695 organic cation transport 1.230866e-4
GO:0046069 cGMP catabolic process 1.327546e-4
GO:0046687 response to chromate 1.336239e-4
GO:0033986 response to methanol 1.336239e-4
GO:2001037 positive regulation of tongue muscle cell differentiation 1.412643e-4
GO:0097152 mesenchymal cell apoptosis 1.412643e-4
GO:0002438 acute inflammatory response to antigenic stimulus 1.412643e-4
GO:0060982 coronary artery morphogenesis 1.412643e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.418272e-4
GO:0000115 regulation of transcription involved in S phase of mitotic cell cycle 1.433527e-4
GO:0046474 glycerophospholipid biosynthetic process 1.437476e-4
GO:0009895 negative regulation of catabolic process 1.448440e-4
GO:0044240 multicellular organismal lipid catabolic process 1.470500e-4
GO:0048320 axial mesoderm formation 1.514788e-4
GO:0042074 cell migration involved in gastrulation 1.535283e-4
GO:0060872 semicircular canal development 1.599074e-4
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 1.620442e-4
GO:0006702 androgen biosynthetic process 1.624467e-4
GO:0090207 regulation of triglyceride metabolic process 1.649695e-4
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.743757e-4
GO:0006085 acetyl-CoA biosynthetic process 1.743757e-4
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 1.767303e-4
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 1.767303e-4
GO:0046039 GTP metabolic process 1.778001e-4
GO:0002019 regulation of renal output by angiotensin 1.825493e-4
GO:0006767 water-soluble vitamin metabolic process 1.858253e-4
GO:0051693 actin filament capping 1.862963e-4
GO:0021526 medial motor column neuron differentiation 1.915755e-4
GO:0033133 positive regulation of glucokinase activity 1.915788e-4
GO:0060621 negative regulation of cholesterol import 1.915788e-4
GO:0016241 regulation of macroautophagy 1.917962e-4
GO:0045453 bone resorption 1.963410e-4
GO:0008033 tRNA processing 1.989253e-4
GO:0003084 positive regulation of systemic arterial blood pressure 2.080709e-4
GO:0097107 postsynaptic density assembly 2.162148e-4
GO:0050668 positive regulation of homocysteine metabolic process 2.162148e-4
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 2.162148e-4
GO:0045963 negative regulation of dopamine metabolic process 2.162148e-4
GO:0015878 biotin transport 2.162148e-4
GO:0015887 pantothenate transmembrane transport 2.162148e-4
GO:0051956 negative regulation of amino acid transport 2.179338e-4
GO:0010591 regulation of lamellipodium assembly 2.185504e-4
GO:0070634 transepithelial ammonium transport 2.228202e-4
GO:0006184 GTP catabolic process 2.276994e-4
GO:0031017 exocrine pancreas development 2.304856e-4
GO:0010507 negative regulation of autophagy 2.319569e-4
GO:0035967 cellular response to topologically incorrect protein 2.323100e-4
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 2.372643e-4
GO:0010713 negative regulation of collagen metabolic process 2.401319e-4
GO:0060707 trophoblast giant cell differentiation 2.441554e-4
GO:0046686 response to cadmium ion 2.442416e-4
GO:0052697 xenobiotic glucuronidation 2.473298e-4
GO:0060286 flagellar cell motility 2.473298e-4
GO:0070980 biphenyl catabolic process 2.473298e-4
GO:0052696 flavonoid glucuronidation 2.473298e-4
GO:0002077 acrosome matrix dispersal 2.473298e-4
GO:0006789 bilirubin conjugation 2.473298e-4
GO:0051552 flavone metabolic process 2.473298e-4
GO:0021528 commissural neuron differentiation in spinal cord 2.473298e-4
GO:0051315 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 2.473298e-4
GO:0051497 negative regulation of stress fiber assembly 2.493756e-4
GO:0032526 response to retinoic acid 2.521025e-4
GO:0055010 ventricular cardiac muscle tissue morphogenesis 2.558632e-4
GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway 2.646438e-4
GO:0042512 negative regulation of tyrosine phosphorylation of Stat1 protein 2.646438e-4
GO:0050666 regulation of homocysteine metabolic process 2.704732e-4
GO:0070286 axonemal dynein complex assembly 2.763859e-4
GO:0051489 regulation of filopodium assembly 2.794780e-4
GO:0032796 uropod organization 2.795782e-4
GO:0060253 negative regulation of glial cell proliferation 2.830262e-4
GO:0003105 negative regulation of glomerular filtration 2.860548e-4
GO:0090031 positive regulation of steroid hormone biosynthetic process 2.867462e-4
GO:2000251 positive regulation of actin cytoskeleton reorganization 3.047440e-4
GO:0060167 regulation of adenosine receptor signaling pathway 3.047440e-4
GO:0031125 rRNA 3'-end processing 3.047440e-4
GO:0060456 positive regulation of digestive system process 3.050932e-4
GO:0045814 negative regulation of gene expression, epigenetic 3.155565e-4
GO:0045217 cell-cell junction maintenance 3.158542e-4
GO:0002432 granuloma formation 3.248196e-4
GO:0046902 regulation of mitochondrial membrane permeability 3.321836e-4
GO:0043574 peroxisomal transport 3.482788e-4
GO:0042274 ribosomal small subunit biogenesis 3.514584e-4
GO:0009069 serine family amino acid metabolic process 3.555211e-4
GO:0071356 cellular response to tumor necrosis factor 3.577041e-4
GO:0051567 histone H3-K9 methylation 3.605766e-4
GO:0006659 phosphatidylserine biosynthetic process 3.609730e-4
GO:0003009 skeletal muscle contraction 3.614542e-4
GO:0071318 cellular response to ATP 3.665935e-4
GO:0006839 mitochondrial transport 3.696960e-4
GO:0045746 negative regulation of Notch signaling pathway 3.743120e-4
GO:0048627 myoblast development 3.797723e-4
GO:0045835 negative regulation of meiosis 3.881417e-4
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 3.912265e-4
GO:0045084 positive regulation of interleukin-12 biosynthetic process 4.087539e-4
GO:0007140 male meiosis 4.306092e-4
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 4.310755e-4
GO:0061302 smooth muscle cell-matrix adhesion 4.310755e-4
GO:0010875 positive regulation of cholesterol efflux 4.547436e-4
GO:0006657 CDP-choline pathway 4.782904e-4
GO:0005979 regulation of glycogen biosynthetic process 4.911030e-4
GO:0032376 positive regulation of cholesterol transport 5.045695e-4
GO:0006625 protein targeting to peroxisome 5.127809e-4
GO:0060319 primitive erythrocyte differentiation 5.130403e-4
GO:0002575 basophil chemotaxis 5.130403e-4
GO:0060706 cell differentiation involved in embryonic placenta development 5.147682e-4
GO:0070625 zymogen granule exocytosis 5.262277e-4
GO:0014895 smooth muscle hypertrophy 5.262277e-4
GO:0003106 negative regulation of glomerular filtration by angiotensin 5.262277e-4
GO:0048484 enteric nervous system development 5.329684e-4
GO:0072053 renal inner medulla development 5.342737e-4
GO:0072054 renal outer medulla development 5.342737e-4
GO:0071072 negative regulation of phospholipid biosynthetic process 5.342737e-4
GO:0051764 actin crosslink formation 5.446611e-4
GO:0060179 male mating behavior 5.459426e-4
GO:0032375 negative regulation of cholesterol transport 5.705207e-4
GO:0030968 endoplasmic reticulum unfolded protein response 5.720123e-4
GO:0032793 positive regulation of CREB transcription factor activity 5.807390e-4
GO:0072376 protein activation cascade 5.881335e-4
GO:0010891 negative regulation of sequestering of triglyceride 5.890036e-4
GO:0035813 regulation of renal sodium excretion 5.942105e-4
GO:0015804 neutral amino acid transport 5.977165e-4
GO:0060014 granulosa cell differentiation 6.094904e-4
GO:0070914 UV-damage excision repair 6.539055e-4
GO:0060160 negative regulation of dopamine receptor signaling pathway 6.539055e-4
GO:0015840 urea transport 6.687215e-4
GO:0032509 endosome transport via multivesicular body sorting pathway 6.820227e-4
GO:0050975 sensory perception of touch 6.892288e-4
GO:0021508 floor plate formation 7.405179e-4
GO:0015862 uridine transport 7.405179e-4
GO:0070417 cellular response to cold 7.411331e-4
GO:0031643 positive regulation of myelination 7.545856e-4
GO:0045541 negative regulation of cholesterol biosynthetic process 7.683870e-4
GO:0030421 defecation 7.683870e-4
GO:0019370 leukotriene biosynthetic process 7.705394e-4
GO:0035357 peroxisome proliferator activated receptor signaling pathway 7.706094e-4
GO:0045017 glycerolipid biosynthetic process 7.790137e-4
GO:0007217 tachykinin receptor signaling pathway 8.018003e-4
GO:0060334 regulation of interferon-gamma-mediated signaling pathway 8.193215e-4
GO:0006506 GPI anchor biosynthetic process 8.382653e-4
GO:0090209 negative regulation of triglyceride metabolic process 8.408792e-4
GO:0042407 cristae formation 8.555683e-4
GO:0010637 negative regulation of mitochondrial fusion 8.555683e-4
GO:0071279 cellular response to cobalt ion 8.555683e-4
GO:0010046 response to mycotoxin 8.555683e-4
GO:0000053 argininosuccinate metabolic process 8.555683e-4
GO:0071071 regulation of phospholipid biosynthetic process 8.626473e-4
GO:0070194 synaptonemal complex disassembly 8.777997e-4
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 8.777997e-4
GO:0006703 estrogen biosynthetic process 8.835354e-4
GO:0046931 pore complex assembly 8.902211e-4
GO:0043301 negative regulation of leukocyte degranulation 9.276569e-4
GO:0070873 regulation of glycogen metabolic process 9.374030e-4
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 9.480406e-4
GO:0006636 unsaturated fatty acid biosynthetic process 9.530312e-4
GO:0010724 regulation of definitive erythrocyte differentiation 9.595876e-4
GO:0071733 transcriptional activation by promoter-enhancer looping 9.595876e-4
GO:0001560 regulation of cell growth by extracellular stimulus 9.606484e-4
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.772242e-4
GO:0071345 cellular response to cytokine stimulus 9.920141e-4
GO:0044154 histone H3-K14 acetylation 9.938445e-4
GO:0033189 response to vitamin A 1.032956e-3
GO:0051588 regulation of neurotransmitter transport 1.046015e-3
GO:0071392 cellular response to estradiol stimulus 1.079235e-3
GO:0046456 icosanoid biosynthetic process 1.111925e-3
GO:0050432 catecholamine secretion 1.113664e-3
GO:0032298 positive regulation of DNA-dependent DNA replication initiation 1.119614e-3
GO:0002636 positive regulation of germinal center formation 1.152938e-3
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.173750e-3
GO:0060708 spongiotrophoblast differentiation 1.189560e-3
GO:0032606 type I interferon production 1.190058e-3
GO:0009443 pyridoxal 5'-phosphate salvage 1.209311e-3
GO:0042424 catecholamine catabolic process 1.212388e-3
GO:0030100 regulation of endocytosis 1.220539e-3
GO:0010982 regulation of high-density lipoprotein particle clearance 1.220987e-3
GO:0006768 biotin metabolic process 1.220987e-3
GO:0051006 positive regulation of lipoprotein lipase activity 1.232996e-3
GO:0002037 negative regulation of L-glutamate transport 1.232996e-3
GO:0045994 positive regulation of translational initiation by iron 1.232996e-3
GO:0006691 leukotriene metabolic process 1.235581e-3
GO:0015858 nucleoside transport 1.256772e-3
GO:0032536 regulation of cell projection size 1.256866e-3
GO:0003229 ventricular cardiac muscle tissue development 1.263952e-3
GO:0044027 hypermethylation of CpG island 1.268030e-3
GO:0010898 positive regulation of triglyceride catabolic process 1.314366e-3
GO:0070947 neutrophil mediated killing of fungus 1.323214e-3
GO:0003420 regulation of growth plate cartilage chondrocyte proliferation 1.323214e-3
GO:0006423 cysteinyl-tRNA aminoacylation 1.323214e-3
GO:0006706 steroid catabolic process 1.340196e-3
GO:0010906 regulation of glucose metabolic process 1.372586e-3
GO:0032012 regulation of ARF protein signal transduction 1.382089e-3
GO:0051788 response to misfolded protein 1.384933e-3
GO:0032088 negative regulation of NF-kappaB transcription factor activity 1.399491e-3
GO:0019217 regulation of fatty acid metabolic process 1.410665e-3
GO:0015697 quaternary ammonium group transport 1.422147e-3
GO:0030032 lamellipodium assembly 1.468339e-3
GO:0045820 negative regulation of glycolysis 1.472025e-3
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 1.474031e-3
GO:0010985 negative regulation of lipoprotein particle clearance 1.485195e-3
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 1.503317e-3
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.504363e-3
GO:0045078 positive regulation of interferon-gamma biosynthetic process 1.518496e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 1.528005e-3
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 1.545099e-3
GO:0046777 protein autophosphorylation 1.545105e-3
GO:0046627 negative regulation of insulin receptor signaling pathway 1.579956e-3
GO:0050764 regulation of phagocytosis 1.594950e-3
GO:0046128 purine ribonucleoside metabolic process 1.615369e-3
GO:0001885 endothelial cell development 1.616107e-3
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 1.617385e-3
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 1.656522e-3
GO:0003329 pancreatic PP cell fate commitment 1.656522e-3
GO:0003326 pancreatic A cell fate commitment 1.656522e-3
GO:0002554 serotonin secretion by platelet 1.689256e-3
GO:0042989 sequestering of actin monomers 1.702033e-3
GO:0006505 GPI anchor metabolic process 1.710844e-3
GO:0019883 antigen processing and presentation of endogenous antigen 1.777721e-3
GO:0051055 negative regulation of lipid biosynthetic process 1.788333e-3
GO:0072070 loop of Henle development 1.819604e-3
GO:0060252 positive regulation of glial cell proliferation 1.819604e-3
GO:0002418 immune response to tumor cell 1.827671e-3
GO:0051586 positive regulation of dopamine uptake 1.854911e-3
GO:0060580 ventral spinal cord interneuron fate determination 1.854911e-3
GO:0046416 D-amino acid metabolic process 1.854911e-3
GO:0048210 Golgi vesicle fusion to target membrane 1.854911e-3
GO:0003327 type B pancreatic cell fate commitment 1.854911e-3
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1.923171e-3
GO:0060711 labyrinthine layer development 1.929122e-3
GO:0048352 paraxial mesoderm structural organization 1.957400e-3
GO:0021998 neural plate mediolateral regionalization 1.957400e-3
GO:0009440 cyanate catabolic process 1.957400e-3
GO:0035020 regulation of Rac protein signal transduction 1.977667e-3
GO:0030835 negative regulation of actin filament depolymerization 1.991683e-3
GO:0030490 maturation of SSU-rRNA 2.020020e-3
GO:0071496 cellular response to external stimulus 2.041220e-3
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion 2.057746e-3
GO:0033131 regulation of glucokinase activity 2.060383e-3
GO:0071956 cellular component maintenance at cellular level 2.067759e-3
GO:0042886 amide transport 2.067759e-3
GO:0021843 substrate-independent telencephalic tangential interneuron migration 2.082492e-3
GO:0002268 follicular dendritic cell differentiation 2.082492e-3
GO:0010893 positive regulation of steroid biosynthetic process 2.092918e-3
GO:0032321 positive regulation of Rho GTPase activity 2.153930e-3
GO:0045218 zonula adherens maintenance 2.179072e-3
GO:0016056 rhodopsin mediated signaling pathway 2.204570e-3
GO:0010912 positive regulation of isomerase activity 2.260832e-3
GO:0090205 positive regulation of cholesterol metabolic process 2.287208e-3
GO:0034097 response to cytokine stimulus 2.305056e-3
GO:0032984 macromolecular complex disassembly 2.320385e-3
GO:0006525 arginine metabolic process 2.377335e-3
GO:0006695 cholesterol biosynthetic process 2.377779e-3
GO:0008594 photoreceptor cell morphogenesis 2.382101e-3
GO:0045922 negative regulation of fatty acid metabolic process 2.389510e-3
GO:0051004 regulation of lipoprotein lipase activity 2.405062e-3
GO:0032365 intracellular lipid transport 2.405062e-3
GO:0060112 generation of ovulation cycle rhythm 2.459427e-3
GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway 2.463422e-3
GO:0061370 testosterone biosynthetic process 2.463422e-3
GO:0033595 response to genistein 2.463422e-3
GO:0050756 fractalkine metabolic process 2.463422e-3
GO:0070842 aggresome assembly 2.469455e-3
GO:0060448 dichotomous subdivision of terminal units involved in lung branching 2.469455e-3
GO:0043304 regulation of mast cell degranulation 2.488057e-3
GO:0010745 negative regulation of macrophage derived foam cell differentiation 2.488057e-3
GO:0006097 glyoxylate cycle 2.491646e-3
GO:0040030 regulation of molecular function, epigenetic 2.491646e-3
GO:0065002 intracellular protein transmembrane transport 2.499155e-3
GO:0043628 ncRNA 3'-end processing 2.499155e-3
GO:0010984 regulation of lipoprotein particle clearance 2.559913e-3
GO:0015844 monoamine transport 2.612030e-3
GO:0032856 activation of Ras GTPase activity 2.632585e-3
GO:0000212 meiotic spindle organization 2.687408e-3
GO:0002357 defense response to tumor cell 2.694447e-3
GO:0008203 cholesterol metabolic process 2.726530e-3
GO:0000185 activation of MAPKKK activity 2.784772e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 2.867028e-3
GO:0030031 cell projection assembly 2.915435e-3
GO:0030224 monocyte differentiation 2.921382e-3
GO:0034612 response to tumor necrosis factor 3.022764e-3
GO:0090136 epithelial cell-cell adhesion 3.085743e-3
GO:0010872 regulation of cholesterol esterification 3.095456e-3
GO:0048570 notochord morphogenesis 3.122230e-3
GO:0048790 maintenance of presynaptic active zone structure 3.138339e-3
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 3.138339e-3
GO:0045948 positive regulation of translational initiation 3.175366e-3
GO:0002115 store-operated calcium entry 3.231913e-3
GO:0008064 regulation of actin polymerization or depolymerization 3.234795e-3
GO:0060349 bone morphogenesis 3.243315e-3
GO:0051882 mitochondrial depolarization 3.315206e-3
GO:0060263 regulation of respiratory burst 3.326487e-3
GO:0015696 ammonium transport 3.350337e-3
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 3.350337e-3
GO:0070602 regulation of centromeric sister chromatid cohesion 3.399331e-3
GO:0016242 negative regulation of macroautophagy 3.402525e-3
GO:0006669 sphinganine-1-phosphate biosynthetic process 3.402525e-3
GO:0006400 tRNA modification 3.432264e-3
GO:0003416 endochondral bone growth 3.437155e-3
GO:0016125 sterol metabolic process 3.457251e-3
GO:0045075 regulation of interleukin-12 biosynthetic process 3.495482e-3
GO:0046847 filopodium assembly 3.529137e-3
GO:0031331 positive regulation of cellular catabolic process 3.569926e-3
GO:0060236 regulation of mitotic spindle organization 3.585533e-3
GO:0034470 ncRNA processing 3.586368e-3
GO:0001916 positive regulation of T cell mediated cytotoxicity 3.703000e-3
GO:0048143 astrocyte activation 3.734210e-3
GO:0035722 interleukin-12-mediated signaling pathway 3.734210e-3
GO:0016557 peroxisome membrane biogenesis 3.779592e-3
GO:0008625 induction of apoptosis via death domain receptors 3.789107e-3
GO:0042278 purine nucleoside metabolic process 3.821300e-3
GO:0060290 transdifferentiation 3.869845e-3
GO:0032319 regulation of Rho GTPase activity 3.906763e-3
GO:0002455 humoral immune response mediated by circulating immunoglobulin 3.942263e-3
GO:0046502 uroporphyrinogen III metabolic process 3.993845e-3
GO:0034770 histone H4-K20 methylation 3.993845e-3
GO:0032049 cardiolipin biosynthetic process 3.993845e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0033239 negative regulation of cellular amine metabolic process 5.171475e-10
GO:0010900 negative regulation of phosphatidylcholine catabolic process 1.892120e-8
GO:0046580 negative regulation of Ras protein signal transduction 7.198656e-8
GO:0060696 regulation of phospholipid catabolic process 1.061468e-7
GO:0051058 negative regulation of small GTPase mediated signal transduction 2.724263e-7
GO:0046339 diacylglycerol metabolic process 3.251865e-7
GO:0042267 natural killer cell mediated cytotoxicity 5.194940e-7
GO:0032375 negative regulation of cholesterol transport 1.287886e-6
GO:0045723 positive regulation of fatty acid biosynthetic process 1.419402e-6
GO:0014819 regulation of skeletal muscle contraction 1.759433e-6
GO:0051135 positive regulation of NK T cell activation 1.799103e-6
GO:0018022 peptidyl-lysine methylation 1.805883e-6
GO:0006654 phosphatidic acid biosynthetic process 2.697620e-6
GO:2000465 regulation of glycogen (starch) synthase activity 5.595609e-6
GO:0090208 positive regulation of triglyceride metabolic process 5.796344e-6
GO:0015884 folic acid transport 6.207697e-6
GO:0010898 positive regulation of triglyceride catabolic process 7.814284e-6
GO:0032374 regulation of cholesterol transport 7.862152e-6
GO:0046015 regulation of transcription by glucose 8.913295e-6
GO:0050728 negative regulation of inflammatory response 9.145031e-6
GO:0030421 defecation 9.357682e-6
GO:0032049 cardiolipin biosynthetic process 9.457748e-6
GO:0001909 leukocyte mediated cytotoxicity 9.688516e-6
GO:0010565 regulation of cellular ketone metabolic process 1.141560e-5
GO:0034447 very-low-density lipoprotein particle clearance 1.395667e-5
GO:0061014 positive regulation of mRNA catabolic process 1.508030e-5
GO:0051181 cofactor transport 1.662969e-5
GO:0015718 monocarboxylic acid transport 1.946385e-5
GO:0015908 fatty acid transport 2.039113e-5
GO:0034261 negative regulation of Ras GTPase activity 2.145713e-5
GO:2000467 positive regulation of glycogen (starch) synthase activity 2.158168e-5
GO:0048240 sperm capacitation 2.675085e-5
GO:0001829 trophectodermal cell differentiation 2.924906e-5
GO:0035966 response to topologically incorrect protein 3.224511e-5
GO:0018023 peptidyl-lysine trimethylation 3.231556e-5
GO:0010614 negative regulation of cardiac muscle hypertrophy 3.780494e-5
GO:0072012 glomerulus vasculature development 3.845256e-5
GO:0070509 calcium ion import 3.882682e-5
GO:0015891 siderophore transport 4.153959e-5
GO:0010906 regulation of glucose metabolic process 4.250439e-5
GO:0014741 negative regulation of muscle hypertrophy 4.452728e-5
GO:0033700 phospholipid efflux 4.981803e-5
GO:0032012 regulation of ARF protein signal transduction 5.044059e-5
GO:0042304 regulation of fatty acid biosynthetic process 5.125711e-5
GO:2000251 positive regulation of actin cytoskeleton reorganization 5.554454e-5
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 5.963492e-5
GO:0016575 histone deacetylation 7.539617e-5
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 7.936980e-5
GO:0046628 positive regulation of insulin receptor signaling pathway 8.872900e-5
GO:0033344 cholesterol efflux 8.949723e-5
GO:0051693 actin filament capping 9.005849e-5
GO:0043320 natural killer cell degranulation 9.139780e-5
GO:0006474 N-terminal protein amino acid acetylation 9.621157e-5
GO:0090207 regulation of triglyceride metabolic process 9.802691e-5
GO:0015909 long-chain fatty acid transport 9.802691e-5
GO:0071715 icosanoid transport 9.868526e-5
GO:0000305 response to oxygen radical 1.019873e-4
GO:0072126 positive regulation of glomerular mesangial cell proliferation 1.038293e-4
GO:0071506 cellular response to mycophenolic acid 1.038293e-4
GO:0060457 negative regulation of digestive system process 1.087265e-4
GO:0061370 testosterone biosynthetic process 1.165562e-4
GO:0006415 translational termination 1.269368e-4
GO:0090130 tissue migration 1.330470e-4
GO:0018026 peptidyl-lysine monomethylation 1.387698e-4
GO:0046889 positive regulation of lipid biosynthetic process 1.456970e-4
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 1.461322e-4
GO:0034260 negative regulation of GTPase activity 1.488235e-4
GO:0045026 plasma membrane fusion 1.520419e-4
GO:0045014 negative regulation of transcription by glucose 1.615308e-4
GO:0010870 positive regulation of receptor biosynthetic process 1.615308e-4
GO:0017156 calcium ion-dependent exocytosis 1.659795e-4
GO:0010452 histone H3-K36 methylation 1.665925e-4
GO:0045834 positive regulation of lipid metabolic process 1.913926e-4
GO:0061034 olfactory bulb mitral cell layer development 2.046562e-4
GO:0018230 peptidyl-L-cysteine S-palmitoylation 2.052513e-4
GO:0045351 type I interferon biosynthetic process 2.052985e-4
GO:0043154 negative regulation of caspase activity 2.220852e-4
GO:0060014 granulosa cell differentiation 2.337021e-4
GO:0045835 negative regulation of meiosis 2.386792e-4
GO:0051006 positive regulation of lipoprotein lipase activity 2.443448e-4
GO:0015914 phospholipid transport 2.819905e-4
GO:0035601 protein deacylation 2.869831e-4
GO:0051788 response to misfolded protein 3.184060e-4
GO:0010224 response to UV-B 3.205383e-4
GO:0010948 negative regulation of cell cycle process 3.216462e-4
GO:0031444 slow-twitch skeletal muscle fiber contraction 3.224768e-4
GO:0060290 transdifferentiation 3.313278e-4
GO:0032369 negative regulation of lipid transport 3.631737e-4
GO:0031331 positive regulation of cellular catabolic process 3.673309e-4
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 3.778519e-4
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 3.778519e-4
GO:0002886 regulation of myeloid leukocyte mediated immunity 3.797845e-4
GO:0007342 fusion of sperm to egg plasma membrane 4.042167e-4
GO:0046168 glycerol-3-phosphate catabolic process 4.100911e-4
GO:0042506 tyrosine phosphorylation of Stat5 protein 4.100911e-4
GO:0016338 calcium-independent cell-cell adhesion 4.113599e-4
GO:0006651 diacylglycerol biosynthetic process 4.271727e-4
GO:0072668 tubulin complex biogenesis 4.557492e-4
GO:0001885 endothelial cell development 4.735518e-4
GO:0006476 protein deacetylation 5.004866e-4
GO:0046686 response to cadmium ion 5.080162e-4
GO:0030913 paranodal junction assembly 5.088249e-4
GO:0071072 negative regulation of phospholipid biosynthetic process 5.112275e-4
GO:0031365 N-terminal protein amino acid modification 5.324635e-4
GO:0032048 cardiolipin metabolic process 5.399105e-4
GO:0046655 folic acid metabolic process 5.399105e-4
GO:0030834 regulation of actin filament depolymerization 5.416636e-4
GO:0035307 positive regulation of protein dephosphorylation 5.531146e-4
GO:0050482 arachidonic acid secretion 5.729584e-4
GO:0032007 negative regulation of TOR signaling cascade 5.740235e-4
GO:0016188 synaptic vesicle maturation 5.759335e-4
GO:0000096 sulfur amino acid metabolic process 5.988658e-4
GO:0002385 mucosal immune response 6.117846e-4
GO:0042593 glucose homeostasis 6.248491e-4
GO:0009082 branched chain family amino acid biosynthetic process 6.358155e-4
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 6.424478e-4
GO:0030336 negative regulation of cell migration 6.538390e-4
GO:0032312 regulation of ARF GTPase activity 6.726159e-4
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 6.769654e-4
GO:0072110 glomerular mesangial cell proliferation 6.822107e-4
GO:0010985 negative regulation of lipoprotein particle clearance 6.997428e-4
GO:0032429 regulation of phospholipase A2 activity 7.020216e-4
GO:0034551 mitochondrial respiratory chain complex III assembly 7.070642e-4
GO:0034382 chylomicron remnant clearance 7.435029e-4
GO:0042946 glucoside transport 7.609189e-4
GO:0002432 granuloma formation 7.609189e-4
GO:0006420 arginyl-tRNA aminoacylation 7.609189e-4
GO:0033238 regulation of cellular amine metabolic process 7.707948e-4
GO:0090177 establishment of planar polarity involved in neural tube closure 7.880546e-4
GO:0010312 detoxification of zinc ion 7.880546e-4
GO:0035306 positive regulation of dephosphorylation 7.887490e-4
GO:2000227 negative regulation of pancreatic A cell differentiation 8.394337e-4
GO:2000978 negative regulation of forebrain neuron differentiation 8.394337e-4
GO:0061106 negative regulation of stomach neuroendocrine cell differentiation 8.394337e-4
GO:0046331 lateral inhibition 8.394337e-4
GO:0032863 activation of Rac GTPase activity 8.452407e-4
GO:0072109 glomerular mesangium development 8.647117e-4
GO:0042420 dopamine catabolic process 8.843617e-4
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.843617e-4
GO:0018342 protein prenylation 8.964016e-4
GO:0044062 regulation of excretion 9.012399e-4
GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade 9.403415e-4
GO:0015724 formate transport 9.612107e-4
GO:0010918 positive regulation of mitochondrial membrane potential 9.612107e-4
GO:0000059 protein import into nucleus, docking 9.612107e-4
GO:0003219 cardiac right ventricle formation 9.660202e-4
GO:0042107 cytokine metabolic process 9.777673e-4
GO:0046717 acid secretion 1.008335e-3
GO:0006700 C21-steroid hormone biosynthetic process 1.014859e-3
GO:0043314 negative regulation of neutrophil degranulation 1.021818e-3
GO:0018198 peptidyl-cysteine modification 1.024667e-3
GO:0043301 negative regulation of leukocyte degranulation 1.107480e-3
GO:0006837 serotonin transport 1.107480e-3
GO:0000303 response to superoxide 1.136167e-3
GO:0006546 glycine catabolic process 1.165184e-3
GO:0043300 regulation of leukocyte degranulation 1.188895e-3
GO:0050994 regulation of lipid catabolic process 1.218595e-3
GO:0032272 negative regulation of protein polymerization 1.227810e-3
GO:0019318 hexose metabolic process 1.229869e-3
GO:0002251 organ or tissue specific immune response 1.250515e-3
GO:0010984 regulation of lipoprotein particle clearance 1.251608e-3
GO:2000210 positive regulation of anoikis 1.303052e-3
GO:0032020 ISG15-protein conjugation 1.416629e-3
GO:2000491 positive regulation of hepatic stellate cell activation 1.419724e-3
GO:0055014 atrial cardiac muscle cell development 1.475032e-3
GO:0021558 trochlear nerve development 1.475032e-3
GO:0019430 removal of superoxide radicals 1.484561e-3
GO:0032862 activation of Rho GTPase activity 1.496304e-3
GO:0048664 neuron fate determination 1.497273e-3
GO:0060160 negative regulation of dopamine receptor signaling pathway 1.504306e-3
GO:0045796 negative regulation of intestinal cholesterol absorption 1.504306e-3
GO:0071877 regulation of adrenergic receptor signaling pathway 1.504306e-3
GO:0035419 activation of MAPK activity involved in innate immune response 1.504306e-3
GO:0010949 negative regulation of intestinal phytosterol absorption 1.504306e-3
GO:0034635 glutathione transport 1.504306e-3
GO:0090031 positive regulation of steroid hormone biosynthetic process 1.521104e-3
GO:0005978 glycogen biosynthetic process 1.528880e-3
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 1.535744e-3
GO:0051488 activation of anaphase-promoting complex activity 1.540953e-3
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.541273e-3
GO:0006620 posttranslational protein targeting to membrane 1.560282e-3
GO:0046890 regulation of lipid biosynthetic process 1.586552e-3
GO:0090076 relaxation of skeletal muscle 1.636254e-3
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 1.636254e-3
GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway 1.647168e-3
GO:0019217 regulation of fatty acid metabolic process 1.675985e-3
GO:0060191 regulation of lipase activity 1.684270e-3
GO:0001825 blastocyst formation 1.700588e-3
GO:0035094 response to nicotine 1.745804e-3
GO:0046341 CDP-diacylglycerol metabolic process 1.777120e-3
GO:0010735 positive regulation of transcription via serum response element binding 1.777120e-3
GO:0006109 regulation of carbohydrate metabolic process 1.791611e-3
GO:0033085 negative regulation of T cell differentiation in thymus 1.830640e-3
GO:0021679 cerebellar molecular layer development 1.847045e-3
GO:0021750 vestibular nucleus development 1.847045e-3
GO:0021590 cerebellum maturation 1.847045e-3
GO:0017004 cytochrome complex assembly 1.847045e-3
GO:0000072 M phase specific microtubule process 1.847045e-3
GO:0043278 response to morphine 1.917475e-3
GO:0060561 apoptosis involved in morphogenesis 1.924348e-3
GO:0032321 positive regulation of Rho GTPase activity 1.983369e-3
GO:0010631 epithelial cell migration 2.005486e-3
GO:0010675 regulation of cellular carbohydrate metabolic process 2.023682e-3
GO:0007290 spermatid nucleus elongation 2.038492e-3
GO:0042228 interleukin-8 biosynthetic process 2.080072e-3
GO:0032782 bile acid secretion 2.080072e-3
GO:0051447 negative regulation of meiotic cell cycle 2.080072e-3
GO:0003096 renal sodium ion transport 2.080072e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 2.080072e-3
GO:0006986 response to unfolded protein 2.084962e-3
GO:0007339 binding of sperm to zona pellucida 2.103817e-3
GO:0031440 regulation of mRNA 3'-end processing 2.118323e-3
GO:0021555 midbrain-hindbrain boundary morphogenesis 2.118323e-3
GO:0032368 regulation of lipid transport 2.135527e-3
GO:0007021 tubulin complex assembly 2.145721e-3
GO:0060490 lateral sprouting involved in lung morphogenesis 2.164230e-3
GO:0060489 planar dichotomous subdivision of terminal units involved in lung branching morphogenesis 2.164230e-3
GO:0048105 establishment of body hair planar orientation 2.164230e-3
GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis 2.164230e-3
GO:0031329 regulation of cellular catabolic process 2.188430e-3
GO:0009081 branched chain family amino acid metabolic process 2.203635e-3
GO:0045792 negative regulation of cell size 2.304953e-3
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 2.313770e-3
GO:0030835 negative regulation of actin filament depolymerization 2.325211e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 2.325361e-3
GO:0061196 fungiform papilla development 2.356370e-3
GO:0071071 regulation of phospholipid biosynthetic process 2.379709e-3
GO:0046340 diacylglycerol catabolic process 2.404116e-3
GO:0090234 regulation of kinetochore assembly 2.415655e-3
GO:0061088 regulation of sequestering of zinc ion 2.415655e-3
GO:0090169 regulation of spindle assembly 2.415655e-3
GO:0051781 positive regulation of cell division 2.432478e-3
GO:0045923 positive regulation of fatty acid metabolic process 2.445719e-3
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 2.553254e-3
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.553254e-3
GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine 2.553254e-3
GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.553254e-3
GO:0051323 metaphase 2.579221e-3
GO:0030002 cellular anion homeostasis 2.783383e-3
GO:0009912 auditory receptor cell fate commitment 2.792445e-3
GO:0006006 glucose metabolic process 2.823735e-3
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.833416e-3
GO:2000273 positive regulation of receptor activity 2.835310e-3
GO:0046755 non-lytic virus budding 2.847638e-3
GO:0055026 negative regulation of cardiac muscle tissue development 2.847638e-3
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 2.847638e-3
GO:0070831 basement membrane assembly 2.847638e-3
GO:0006391 transcription initiation from mitochondrial promoter 2.847638e-3
GO:0018364 peptidyl-glutamine methylation 2.847638e-3
GO:0032971 regulation of muscle filament sliding 2.847638e-3
GO:0061308 cardiac neural crest cell development involved in heart development 2.893529e-3
GO:0045608 negative regulation of auditory receptor cell differentiation 2.953755e-3
GO:0033211 adiponectin-mediated signaling pathway 3.034815e-3
GO:0019388 galactose catabolic process 3.051919e-3
GO:0032606 type I interferon production 3.052549e-3
GO:0043353 enucleate erythrocyte differentiation 3.052549e-3
GO:0007217 tachykinin receptor signaling pathway 3.052549e-3
GO:0060193 positive regulation of lipase activity 3.098597e-3
GO:0035441 cell migration involved in vasculogenesis 3.121000e-3
GO:0010868 negative regulation of triglyceride biosynthetic process 3.145072e-3
GO:0031442 positive regulation of mRNA 3'-end processing 3.216174e-3
GO:0010896 regulation of triglyceride catabolic process 3.272629e-3
GO:0045017 glycerolipid biosynthetic process 3.306427e-3
GO:0045721 negative regulation of gluconeogenesis 3.395494e-3
GO:0006998 nuclear envelope organization 3.501155e-3
GO:0097150 neuronal stem cell maintenance 3.582646e-3
GO:0090002 establishment of protein localization in plasma membrane 3.582646e-3
GO:0061198 fungiform papilla formation 3.582646e-3
GO:0032328 alanine transport 3.582646e-3
GO:0043313 regulation of neutrophil degranulation 3.725007e-3
GO:0035907 dorsal aorta development 3.788014e-3
GO:0007094 mitotic cell cycle spindle assembly checkpoint 3.788014e-3
GO:0034498 early endosome to Golgi transport 3.797810e-3
GO:2000146 negative regulation of cell motility 3.817781e-3
GO:0051156 glucose 6-phosphate metabolic process 3.878596e-3
GO:0010874 regulation of cholesterol efflux 3.922311e-3
GO:0009083 branched chain family amino acid catabolic process 3.992056e-3
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 4.017318e-3
GO:0006116 NADH oxidation 4.056238e-3
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 4.056238e-3
GO:0043467 regulation of generation of precursor metabolites and energy 4.083934e-3
GO:0031117 positive regulation of microtubule depolymerization 4.139349e-3
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 4.139349e-3
GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose 4.139349e-3
GO:0035814 negative regulation of renal sodium excretion 4.161737e-3
GO:0032984 macromolecular complex disassembly 4.226824e-3
GO:0071173 spindle assembly checkpoint 4.309846e-3
GO:0033131 regulation of glucokinase activity 4.309846e-3
GO:0010907 positive regulation of glucose metabolic process 4.354087e-3
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity 4.388580e-3
GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis 4.418035e-3
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 4.501257e-3
GO:0055107 Golgi to secretory granule transport 4.501257e-3
GO:0045358 negative regulation of interferon-beta biosynthetic process 4.501257e-3
GO:0060385 axonogenesis involved in innervation 4.501257e-3
GO:0015878 biotin transport 4.501257e-3
GO:0015887 pantothenate transmembrane transport 4.501257e-3
GO:0032972 regulation of muscle filament sliding speed 4.501257e-3
GO:0034651 cortisol biosynthetic process 4.501257e-3
GO:0035865 cellular response to potassium ion 4.501257e-3
GO:0043547 positive regulation of GTPase activity 4.505285e-3
GO:0061099 negative regulation of protein tyrosine kinase activity 4.513365e-3
GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis 4.608061e-3
GO:0060695 negative regulation of cholesterol transporter activity 4.608061e-3
GO:0050756 fractalkine metabolic process 4.608061e-3
GO:0033595 response to genistein 4.608061e-3
GO:0006701 progesterone biosynthetic process 4.608061e-3
GO:0015759 beta-glucoside transport 4.608061e-3
GO:0051497 negative regulation of stress fiber assembly 4.641474e-3
GO:0018094 protein polyglycylation 4.675208e-3
GO:0050996 positive regulation of lipid catabolic process 4.739643e-3
GO:0072333 signal transduction by p53 class mediator resulting in induction of anoikis 4.761419e-3
GO:0070375 BMK cascade 4.761419e-3
GO:0032318 regulation of Ras GTPase activity 4.791943e-3
GO:0042668 auditory receptor cell fate determination 5.025146e-3
GO:0046498 S-adenosylhomocysteine metabolic process 5.081056e-3
GO:0060448 dichotomous subdivision of terminal units involved in lung branching 5.088422e-3
GO:0019405 alditol catabolic process 5.088422e-3
GO:0061028 establishment of endothelial barrier 5.111692e-3
GO:0031577 spindle checkpoint 5.180414e-3
GO:0035583 negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta 5.183687e-3
GO:0019532 oxalate transport 5.183687e-3
GO:0021681 cerebellar granular layer development 5.296586e-3
GO:0072337 modified amino acid transport 5.308747e-3
GO:0072011 glomerular endothelium development 5.339353e-3
GO:2000188 regulation of cholesterol homeostasis 5.339353e-3
GO:0046333 octopamine metabolic process 5.339353e-3
GO:0042309 homoiothermy 5.339353e-3
GO:0007168 receptor guanylyl cyclase signaling pathway 5.395041e-3
GO:0021578 hindbrain maturation 5.395041e-3
GO:0001835 blastocyst hatching 5.395041e-3
GO:2000974 negative regulation of pro-B cell differentiation 5.465941e-3
GO:0030644 cellular chloride ion homeostasis 5.465941e-3
GO:0071218 cellular response to misfolded protein 5.499189e-3
GO:0030718 germ-line stem cell maintenance 5.499189e-3
GO:0008078 mesodermal cell migration 5.514617e-3
GO:0071879 positive regulation of adrenergic receptor signaling pathway 5.614529e-3
GO:0070267 oncosis 5.614529e-3
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 5.614529e-3
GO:0048243 norepinephrine secretion 5.614529e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 5.665852e-3
GO:0002674 negative regulation of acute inflammatory response 5.717867e-3
GO:0048635 negative regulation of muscle organ development 5.720689e-3
GO:0046688 response to copper ion 5.732293e-3
GO:0022038 corpus callosum development 5.923208e-3
GO:0071174 mitotic cell cycle spindle checkpoint 6.004133e-3
GO:0060347 heart trabecula formation 6.004215e-3
GO:0006354 transcription elongation, DNA-dependent 6.026648e-3
GO:0007340 acrosome reaction 6.143639e-3
GO:0070972 protein localization in endoplasmic reticulum 6.151919e-3
GO:0009166 nucleotide catabolic process 6.188023e-3
GO:0097039 protein linear polyubiquitination 6.189269e-3
GO:0045047 protein targeting to ER 6.279868e-3
GO:0015698 inorganic anion transport 6.302107e-3
GO:0046499 S-adenosylmethioninamine metabolic process 6.340508e-3
GO:0045345 positive regulation of MHC class I biosynthetic process 6.588717e-3
GO:0045875 negative regulation of sister chromatid cohesion 6.588717e-3
GO:0033278 cell proliferation in midbrain 6.588717e-3
GO:0006669 sphinganine-1-phosphate biosynthetic process 6.588717e-3
GO:0046886 positive regulation of hormone biosynthetic process 6.606481e-3
GO:0071333 cellular response to glucose stimulus 6.657928e-3
GO:0000089 mitotic metaphase 6.663848e-3
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 6.677581e-3
GO:0072078 nephron tubule morphogenesis 6.698269e-3
GO:0032320 positive regulation of Ras GTPase activity 6.744679e-3
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 6.768494e-3
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 6.768494e-3
GO:0051387 negative regulation of nerve growth factor receptor signaling pathway 6.768494e-3
GO:0044275 cellular carbohydrate catabolic process 6.834114e-3
GO:0032700 negative regulation of interleukin-17 production 6.835693e-3
GO:0007143 female meiosis 6.835693e-3
GO:0051051 negative regulation of transport 6.886817e-3
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 6.975315e-3
GO:0002426 immunoglobulin production in mucosal tissue 6.975315e-3
GO:0051186 cofactor metabolic process 7.044149e-3
GO:0010866 regulation of triglyceride biosynthetic process 7.072275e-3
GO:0006997 nucleus organization 7.073187e-3
GO:0051983 regulation of chromosome segregation 7.094821e-3
GO:0072141 renal interstitial cell development 7.190671e-3
GO:0045332 phospholipid translocation 7.190671e-3
GO:0033108 mitochondrial respiratory chain complex assembly 7.249140e-3
GO:0006111 regulation of gluconeogenesis 7.256543e-3
GO:0071322 cellular response to carbohydrate stimulus 7.291280e-3
GO:2000981 negative regulation of inner ear receptor cell differentiation 7.318512e-3
GO:0071321 cellular response to cGMP 7.319049e-3
GO:0030046 parallel actin filament bundle assembly 7.319049e-3
GO:0060978 angiogenesis involved in coronary vascular morphogenesis 7.319049e-3
GO:0035095 behavioral response to nicotine 7.319049e-3
GO:0032418 lysosome localization 7.319049e-3
GO:0032874 positive regulation of stress-activated MAPK cascade 7.350179e-3
GO:0045988 negative regulation of striated muscle contraction 7.465791e-3
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 7.478102e-3
GO:0016601 Rac protein signal transduction 7.567056e-3
GO:0010875 positive regulation of cholesterol efflux 7.589902e-3
GO:0007063 regulation of sister chromatid cohesion 7.599317e-3
GO:0051055 negative regulation of lipid biosynthetic process 7.771945e-3
GO:0005979 regulation of glycogen biosynthetic process 7.775926e-3
GO:0006337 nucleosome disassembly 7.925446e-3
GO:0022616 DNA strand elongation 8.199788e-3
GO:0050668 positive regulation of homocysteine metabolic process 8.220967e-3
GO:0070845 polyubiquitinated misfolded protein transport 8.220967e-3
GO:0045963 negative regulation of dopamine metabolic process 8.220967e-3
GO:0043255 regulation of carbohydrate biosynthetic process 8.240951e-3
GO:0007214 gamma-aminobutyric acid signaling pathway 8.346069e-3
GO:0006821 chloride transport 8.360567e-3
GO:0072239 metanephric glomerulus vasculature development 8.389517e-3
GO:0001820 serotonin secretion 8.389517e-3
GO:0048733 sebaceous gland development 8.462406e-3
GO:0033159 negative regulation of protein import into nucleus, translocation 8.462406e-3
GO:0019853 L-ascorbic acid biosynthetic process 8.493189e-3
GO:0017144 drug metabolic process 8.646446e-3
GO:0072539 T-helper 17 cell differentiation 8.698550e-3
GO:0046942 carboxylic acid transport 8.772036e-3
GO:0001678 cellular glucose homeostasis 8.811087e-3
GO:0051403 stress-activated MAPK cascade 8.844998e-3
GO:0006659 phosphatidylserine biosynthetic process 8.844998e-3
GO:0061072 iris morphogenesis 8.890375e-3
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 8.890375e-3
GO:0015874 norepinephrine transport 8.890375e-3
GO:0001893 maternal placenta development 8.908791e-3
GO:0014045 establishment of endothelial blood-brain barrier 9.132947e-3
GO:0030837 negative regulation of actin filament polymerization 9.176719e-3
GO:0016045 detection of bacterium 9.291149e-3
GO:0016052 carbohydrate catabolic process 9.422448e-3
GO:0042398 cellular modified amino acid biosynthetic process 9.447810e-3
GO:0006071 glycerol metabolic process 9.533169e-3
GO:0032856 activation of Ras GTPase activity 9.600111e-3
GO:0060192 negative regulation of lipase activity 9.605368e-3
GO:0019320 hexose catabolic process 9.714836e-3
GO:0045607 regulation of auditory receptor cell differentiation 9.729263e-3
GO:0042424 catecholamine catabolic process 9.729263e-3
GO:0000052 citrulline metabolic process 9.729263e-3
GO:0045872 positive regulation of rhodopsin gene expression 9.740582e-3
GO:0061144 alveolar secondary septum development 9.740582e-3
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 9.740582e-3
GO:0032065 cortical protein anchoring 9.740582e-3
GO:0021528 commissural neuron differentiation in spinal cord 9.740582e-3
GO:0019086 late viral mRNA transcription 9.740582e-3
GO:0001886 endothelial cell morphogenesis 9.741157e-3
GO:0003015 heart process 9.782525e-3
GO:0072086 specification of loop of Henle identity 9.812979e-3
GO:0008654 phospholipid biosynthetic process 9.864293e-3
GO:0072385 minus-end-directed organelle transport along microtubule 9.901874e-3
GO:0023035 CD40 signaling pathway 9.901874e-3
GO:0070873 regulation of glycogen metabolic process 1.011071e-2
GO:0034393 positive regulation of smooth muscle cell apoptosis 1.015318e-2
GO:0006801 superoxide metabolic process 1.015786e-2
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process 1.055538e-2
GO:0051302 regulation of cell division 1.057820e-2
GO:0045833 negative regulation of lipid metabolic process 1.070122e-2
GO:0050883 musculoskeletal movement, spinal reflex action 1.074283e-2
GO:0033504 floor plate development 1.074283e-2
GO:0071593 lymphocyte aggregation 1.086840e-2
GO:0015886 heme transport 1.086840e-2
GO:0070869 heterochromatin formation involved in chromatin silencing 1.086840e-2
GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide 1.086840e-2
GO:0009299 mRNA transcription 1.086840e-2
GO:0006668 sphinganine-1-phosphate metabolic process 1.086840e-2
GO:0071584 negative regulation of zinc ion import 1.103096e-2
GO:0071594 thymocyte aggregation 1.103096e-2
GO:0090281 negative regulation of calcium ion import 1.103096e-2
GO:0046967 cytosol to ER transport 1.103096e-2
GO:0019060 intracellular transport of viral proteins in host cell 1.103096e-2
GO:0006196 AMP catabolic process 1.103096e-2
GO:0046108 uridine metabolic process 1.103096e-2
GO:0034259 negative regulation of Rho GTPase activity 1.103096e-2
GO:0046086 adenosine biosynthetic process 1.103096e-2
GO:0018193 peptidyl-amino acid modification 1.115376e-2
GO:0051494 negative regulation of cytoskeleton organization 1.120487e-2
GO:2000142 regulation of transcription initiation, DNA-dependent 1.124714e-2
GO:0070914 UV-damage excision repair 1.128618e-2
GO:0090292 nuclear matrix anchoring at nuclear membrane 1.128618e-2
GO:0044342 type B pancreatic cell proliferation 1.128618e-2
GO:0042996 regulation of Golgi to plasma membrane protein transport 1.128618e-2
GO:0001830 trophectodermal cell fate commitment 1.128618e-2
GO:0018343 protein farnesylation 1.128618e-2
GO:0035562 negative regulation of chromatin binding 1.128618e-2
GO:0034227 tRNA thio-modification 1.132410e-2
GO:0006177 GMP biosynthetic process 1.132410e-2
GO:0015864 pyrimidine nucleoside transport 1.132410e-2
GO:0033591 response to L-ascorbic acid 1.137066e-2
GO:0050685 positive regulation of mRNA processing 1.150301e-2
GO:0007184 SMAD protein import into nucleus 1.162908e-2
GO:0015849 organic acid transport 1.177559e-2
GO:0006544 glycine metabolic process 1.184915e-2
GO:0010724 regulation of definitive erythrocyte differentiation 1.186231e-2
GO:0006705 mineralocorticoid biosynthetic process 1.186231e-2
GO:0090150 establishment of protein localization in membrane 1.215759e-2
GO:0002758 innate immune response-activating signal transduction 1.218909e-2
GO:0060047 heart contraction 1.223879e-2
GO:0035036 sperm-egg recognition 1.238209e-2
GO:0035813 regulation of renal sodium excretion 1.250830e-2
GO:0032872 regulation of stress-activated MAPK cascade 1.264077e-2
GO:0019511 peptidyl-proline hydroxylation 1.265086e-2
GO:0008633 activation of pro-apoptotic gene products 1.271285e-2
GO:0010824 regulation of centrosome duplication 1.282132e-2
GO:0045930 negative regulation of mitotic cell cycle 1.286673e-2
GO:0046174 polyol catabolic process 1.287111e-2
GO:0045541 negative regulation of cholesterol biosynthetic process 1.287111e-2
GO:0034329 cell junction assembly 1.291829e-2