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Novel motif:24

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name:motif24_AGAACT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0050896 response to stimulus 4.009464e-31
GO:0006952 defense response 2.521652e-26
GO:0051716 cellular response to stimulus 1.782302e-23
GO:0007165 signal transduction 5.847529e-22
GO:0002376 immune system process 2.688806e-20
GO:0006950 response to stress 6.852033e-18
GO:0002684 positive regulation of immune system process 1.407509e-17
GO:0023052 signaling 1.409427e-17
GO:0050776 regulation of immune response 1.202762e-16
GO:0051704 multi-organism process 1.000204e-15
GO:0002697 regulation of immune effector process 1.695142e-15
GO:0009611 response to wounding 1.771248e-15
GO:0007166 cell surface receptor linked signaling pathway 3.126810e-15
GO:0051707 response to other organism 3.938528e-15
GO:0045087 innate immune response 4.230931e-15
GO:0007154 cell communication 7.650626e-15
GO:0050778 positive regulation of immune response 7.934593e-15
GO:0006955 immune response 1.683802e-14
GO:0006954 inflammatory response 6.009832e-14
GO:0009607 response to biotic stimulus 1.146968e-13
GO:0002682 regulation of immune system process 1.817365e-13
GO:0032675 regulation of interleukin-6 production 2.162795e-13
GO:0002253 activation of immune response 3.741575e-13
GO:0002694 regulation of leukocyte activation 4.943230e-13
GO:0042221 response to chemical stimulus 5.804271e-13
GO:0002764 immune response-regulating signaling pathway 6.142081e-13
GO:0019538 protein metabolic process 8.298669e-13
GO:0009617 response to bacterium 9.648901e-13
GO:0051249 regulation of lymphocyte activation 9.699867e-13
GO:0031349 positive regulation of defense response 1.384495e-12
GO:0002757 immune response-activating signal transduction 1.886535e-12
GO:0051384 response to glucocorticoid stimulus 4.340190e-12
GO:0032755 positive regulation of interleukin-6 production 5.223567e-12
GO:0050865 regulation of cell activation 6.866255e-12
GO:0014041 regulation of neuron maturation 7.341109e-12
GO:0019441 tryptophan catabolic process to kynurenine 1.210660e-11
GO:0045137 development of primary sexual characteristics 1.356985e-11
GO:0042742 defense response to bacterium 1.411454e-11
GO:0045088 regulation of innate immune response 1.812311e-11
GO:0042325 regulation of phosphorylation 2.648889e-11
GO:0007548 sex differentiation 4.191779e-11
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 4.807457e-11
GO:0048608 reproductive structure development 4.825922e-11
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 4.871845e-11
GO:0051046 regulation of secretion 6.521357e-11
GO:0050794 regulation of cellular process 7.276498e-11
GO:0002696 positive regulation of leukocyte activation 8.898915e-11
GO:0019220 regulation of phosphate metabolic process 1.006109e-10
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 1.018968e-10
GO:0051251 positive regulation of lymphocyte activation 1.066623e-10
GO:0044267 cellular protein metabolic process 1.459563e-10
GO:0045624 positive regulation of T-helper cell differentiation 1.510011e-10
GO:0045089 positive regulation of innate immune response 1.513053e-10
GO:0045622 regulation of T-helper cell differentiation 1.638725e-10
GO:0060341 regulation of cellular localization 1.642824e-10
GO:0001775 cell activation 2.361397e-10
GO:0046661 male sex differentiation 2.770287e-10
GO:0034329 cell junction assembly 3.220511e-10
GO:0008406 gonad development 3.528524e-10
GO:0046637 regulation of alpha-beta T cell differentiation 4.678215e-10
GO:0031960 response to corticosteroid stimulus 5.598295e-10
GO:0019046 reactivation of latent virus 5.928504e-10
GO:0034341 response to interferon-gamma 6.287682e-10
GO:0070189 kynurenine metabolic process 6.308277e-10
GO:0034330 cell junction organization 9.183612e-10
GO:0050867 positive regulation of cell activation 1.119702e-9
GO:0031347 regulation of defense response 1.127699e-9
GO:0046635 positive regulation of alpha-beta T cell activation 1.204133e-9
GO:0001932 regulation of protein phosphorylation 1.268968e-9
GO:0006508 proteolysis 1.453817e-9
GO:0051179 localization 2.032177e-9
GO:0046638 positive regulation of alpha-beta T cell differentiation 2.155889e-9
GO:0046546 development of primary male sexual characteristics 2.354755e-9
GO:0009100 glycoprotein metabolic process 2.744394e-9
GO:0048583 regulation of response to stimulus 3.273378e-9
GO:0002218 activation of innate immune response 3.467375e-9
GO:0002237 response to molecule of bacterial origin 3.848769e-9
GO:0001817 regulation of cytokine production 4.104649e-9
GO:0045628 regulation of T-helper 2 cell differentiation 5.434514e-9
GO:0043170 macromolecule metabolic process 6.310025e-9
GO:0043004 cytoplasmic sequestering of CFTR protein 7.083046e-9
GO:0032496 response to lipopolysaccharide 9.797049e-9
GO:0050870 positive regulation of T cell activation 1.116789e-8
GO:0051050 positive regulation of transport 1.257702e-8
GO:0051023 regulation of immunoglobulin secretion 1.279127e-8
GO:0034097 response to cytokine stimulus 1.382647e-8
GO:0046634 regulation of alpha-beta T cell activation 1.391084e-8
GO:0065007 biological regulation 1.622709e-8
GO:0051049 regulation of transport 1.642803e-8
GO:0070887 cellular response to chemical stimulus 1.745821e-8
GO:0050830 defense response to Gram-positive bacterium 1.781936e-8
GO:0030216 keratinocyte differentiation 1.805518e-8
GO:0002768 immune response-regulating cell surface receptor signaling pathway 1.862254e-8
GO:0032649 regulation of interferon-gamma production 2.130787e-8
GO:0014043 negative regulation of neuron maturation 2.270011e-8
GO:0008584 male gonad development 2.608691e-8
GO:0019359 nicotinamide nucleotide biosynthetic process 2.610799e-8
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3.276252e-8
GO:0010033 response to organic substance 3.682635e-8
GO:0009435 NAD biosynthetic process 4.207475e-8
GO:0050789 regulation of biological process 4.595673e-8
GO:0046330 positive regulation of JNK cascade 4.742342e-8
GO:0080134 regulation of response to stress 5.119484e-8
GO:0002429 immune response-activating cell surface receptor signaling pathway 6.011236e-8
GO:0002825 regulation of T-helper 1 type immune response 6.782823e-8
GO:0001819 positive regulation of cytokine production 7.644866e-8
GO:0009101 glycoprotein biosynthetic process 7.742701e-8
GO:0031581 hemidesmosome assembly 7.897950e-8
GO:0016192 vesicle-mediated transport 8.231897e-8
GO:0045630 positive regulation of T-helper 2 cell differentiation 8.314146e-8
GO:0045621 positive regulation of lymphocyte differentiation 8.551063e-8
GO:0002819 regulation of adaptive immune response 8.920010e-8
GO:0001655 urogenital system development 8.926689e-8
GO:0006468 protein phosphorylation 9.923324e-8
GO:0007044 cell-substrate junction assembly 1.046852e-7
GO:0023051 regulation of signaling 1.111818e-7
GO:0050851 antigen receptor-mediated signaling pathway 1.115402e-7
GO:0050708 regulation of protein secretion 1.131920e-7
GO:0031111 negative regulation of microtubule polymerization or depolymerization 1.140665e-7
GO:0002758 innate immune response-activating signal transduction 1.141826e-7
GO:0032729 positive regulation of interferon-gamma production 1.194731e-7
GO:0048245 eosinophil chemotaxis 1.212103e-7
GO:0032879 regulation of localization 1.358822e-7
GO:0006569 tryptophan catabolic process 1.368026e-7
GO:0007018 microtubule-based movement 1.378763e-7
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.393542e-7
GO:0050930 induction of positive chemotaxis 1.504910e-7
GO:0002221 pattern recognition receptor signaling pathway 1.792698e-7
GO:0006568 tryptophan metabolic process 1.993465e-7
GO:0044257 cellular protein catabolic process 2.098763e-7
GO:2000348 regulation of CD40 signaling pathway 2.137192e-7
GO:0046660 female sex differentiation 2.184384e-7
GO:0090084 negative regulation of inclusion body assembly 2.369212e-7
GO:0051607 defense response to virus 2.407276e-7
GO:0032663 regulation of interleukin-2 production 2.407276e-7
GO:0031424 keratinization 2.506760e-7
GO:0006464 protein modification process 2.526138e-7
GO:0007186 G-protein coupled receptor protein signaling pathway 2.770082e-7
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 2.889968e-7
GO:0016337 cell-cell adhesion 3.056841e-7
GO:0031110 regulation of microtubule polymerization or depolymerization 3.072519e-7
GO:0030855 epithelial cell differentiation 3.134662e-7
GO:0009888 tissue development 3.211309e-7
GO:0072001 renal system development 3.446237e-7
GO:0051188 cofactor biosynthetic process 3.582173e-7
GO:0048935 peripheral nervous system neuron development 3.643811e-7
GO:0016101 diterpenoid metabolic process 3.743713e-7
GO:0071219 cellular response to molecule of bacterial origin 3.767243e-7
GO:0042904 9-cis-retinoic acid biosynthetic process 3.768285e-7
GO:0006968 cellular defense response 3.815269e-7
GO:0000278 mitotic cell cycle 4.016790e-7
GO:0009913 epidermal cell differentiation 4.064489e-7
GO:0051902 negative regulation of mitochondrial depolarization 4.621918e-7
GO:0048015 phosphatidylinositol-mediated signaling 4.713173e-7
GO:0002828 regulation of type 2 immune response 5.077757e-7
GO:0051603 proteolysis involved in cellular protein catabolic process 5.131099e-7
GO:0050863 regulation of T cell activation 5.132719e-7
GO:0035556 intracellular signal transduction 5.184607e-7
GO:0007155 cell adhesion 5.234153e-7
GO:0051047 positive regulation of secretion 5.409659e-7
GO:0048660 regulation of smooth muscle cell proliferation 5.572777e-7
GO:0002699 positive regulation of immune effector process 5.620187e-7
GO:0046545 development of primary female sexual characteristics 6.253689e-7
GO:0043632 modification-dependent macromolecule catabolic process 6.269383e-7
GO:0010982 regulation of high-density lipoprotein particle clearance 6.350912e-7
GO:0043412 macromolecule modification 6.478748e-7
GO:0006348 chromatin silencing at telomere 6.607829e-7
GO:0071844 cellular component assembly at cellular level 7.294647e-7
GO:0008544 epidermis development 7.325413e-7
GO:0071222 cellular response to lipopolysaccharide 7.683950e-7
GO:0051412 response to corticosterone stimulus 7.736126e-7
GO:0019941 modification-dependent protein catabolic process 7.759424e-7
GO:0032880 regulation of protein localization 8.027515e-7
GO:0065009 regulation of molecular function 8.161831e-7
GO:0048511 rhythmic process 8.608293e-7
GO:0045730 respiratory burst 9.034800e-7
GO:0044260 cellular macromolecule metabolic process 9.071112e-7
GO:0048566 embryonic digestive tract development 9.428212e-7
GO:0042445 hormone metabolic process 9.480682e-7
GO:0030031 cell projection assembly 9.691882e-7
GO:0034754 cellular hormone metabolic process 9.997431e-7
GO:0006887 exocytosis 1.023442e-6
GO:0050829 defense response to Gram-negative bacterium 1.023826e-6
GO:0048769 sarcomerogenesis 1.078540e-6
GO:0016310 phosphorylation 1.113447e-6
GO:0006511 ubiquitin-dependent protein catabolic process 1.143380e-6
GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1.155315e-6
GO:0009072 aromatic amino acid family metabolic process 1.236382e-6
GO:0050715 positive regulation of cytokine secretion 1.255374e-6
GO:0043420 anthranilate metabolic process 1.286882e-6
GO:0034516 response to vitamin B6 1.286882e-6
GO:0030241 skeletal muscle myosin thick filament assembly 1.322852e-6
GO:0002831 regulation of response to biotic stimulus 1.365032e-6
GO:0050714 positive regulation of protein secretion 1.380557e-6
GO:0010040 response to iron(II) ion 1.400703e-6
GO:0051641 cellular localization 1.447617e-6
GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.464592e-6
GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.464592e-6
GO:0008152 metabolic process 1.471629e-6
GO:0050729 positive regulation of inflammatory response 1.482029e-6
GO:0061043 regulation of vascular wound healing 1.548546e-6
GO:0006586 indolalkylamine metabolic process 1.577578e-6
GO:0043497 regulation of protein heterodimerization activity 1.644859e-6
GO:0032735 positive regulation of interleukin-12 production 1.650895e-6
GO:0019442 tryptophan catabolic process to acetyl-CoA 1.660289e-6
GO:0045582 positive regulation of T cell differentiation 1.860286e-6
GO:0006796 phosphate-containing compound metabolic process 1.886237e-6
GO:0008585 female gonad development 1.914680e-6
GO:0009966 regulation of signal transduction 1.991438e-6
GO:0008104 protein localization 2.005283e-6
GO:0051234 establishment of localization 2.062485e-6
GO:0050707 regulation of cytokine secretion 2.074155e-6
GO:0042996 regulation of Golgi to plasma membrane protein transport 2.086524e-6
GO:0001523 retinoid metabolic process 2.122478e-6
GO:0071346 cellular response to interferon-gamma 2.142081e-6
GO:2000345 regulation of hepatocyte proliferation 2.149850e-6
GO:0006447 regulation of translational initiation by iron 2.345099e-6
GO:0045623 negative regulation of T-helper cell differentiation 2.381153e-6
GO:0016199 axon midline choice point recognition 2.393423e-6
GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 2.459523e-6
GO:0042997 negative regulation of Golgi to plasma membrane protein transport 2.471163e-6
GO:0048584 positive regulation of response to stimulus 2.498936e-6
GO:0019363 pyridine nucleotide biosynthetic process 2.499382e-6
GO:0051338 regulation of transferase activity 2.670323e-6
GO:0019674 NAD metabolic process 2.837377e-6
GO:0032330 regulation of chondrocyte differentiation 2.876467e-6
GO:0045625 regulation of T-helper 1 cell differentiation 2.899194e-6
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 2.920651e-6
GO:0044238 primary metabolic process 2.936671e-6
GO:0045069 regulation of viral genome replication 2.983826e-6
GO:0022607 cellular component assembly 2.994734e-6
GO:0032467 positive regulation of cytokinesis 3.147182e-6
GO:0032501 multicellular organismal process 3.172518e-6
GO:0043549 regulation of kinase activity 3.199509e-6
GO:0018874 benzoate metabolic process 3.282684e-6
GO:0044070 regulation of anion transport 3.417782e-6
GO:0060409 positive regulation of acetylcholine metabolic process 3.445571e-6
GO:0051223 regulation of protein transport 3.449394e-6
GO:0045626 negative regulation of T-helper 1 cell differentiation 3.455275e-6
GO:0010817 regulation of hormone levels 3.472791e-6
GO:0007156 homophilic cell adhesion 3.514420e-6
GO:0050864 regulation of B cell activation 3.609980e-6
GO:0042384 cilium assembly 3.662400e-6
GO:0010741 negative regulation of intracellular protein kinase cascade 3.925749e-6
GO:0048857 neural nucleus development 4.278920e-6
GO:2000351 regulation of endothelial cell apoptosis 4.315488e-6
GO:0070201 regulation of establishment of protein localization 4.476960e-6
GO:0015827 tryptophan transport 4.667265e-6
GO:0050790 regulation of catalytic activity 4.778661e-6
GO:0043269 regulation of ion transport 4.804251e-6
GO:0045321 leukocyte activation 4.844825e-6
GO:0010627 regulation of intracellular protein kinase cascade 4.868587e-6
GO:0065008 regulation of biological quality 5.418000e-6
GO:0001656 metanephros development 5.729010e-6
GO:0061039 ovum-producing ovary development 5.835043e-6
GO:0050691 regulation of defense response to virus by host 5.844217e-6
GO:0050727 regulation of inflammatory response 6.062985e-6
GO:0030163 protein catabolic process 6.276262e-6
GO:0042060 wound healing 6.495663e-6
GO:0042574 retinal metabolic process 6.807200e-6
GO:0044093 positive regulation of molecular function 6.870855e-6
GO:0007049 cell cycle 7.000813e-6
GO:0045994 positive regulation of translational initiation by iron 7.356632e-6
GO:0002037 negative regulation of L-glutamate transport 7.356632e-6
GO:0043550 regulation of lipid kinase activity 8.370661e-6
GO:0006810 transport 8.443863e-6
GO:0050673 epithelial cell proliferation 8.473150e-6
GO:0007264 small GTPase mediated signal transduction 8.497698e-6
GO:0048513 organ development 8.606514e-6
GO:0000165 MAPKKK cascade 8.860766e-6
GO:0006928 cellular component movement 9.232764e-6
GO:0022402 cell cycle process 9.314600e-6
GO:0061035 regulation of cartilage development 9.416914e-6
GO:0007076 mitotic chromosome condensation 9.789815e-6
GO:0016043 cellular component organization 1.002116e-5
GO:0045619 regulation of lymphocyte differentiation 1.030734e-5
GO:0019722 calcium-mediated signaling 1.033484e-5
GO:0032825 positive regulation of natural killer cell differentiation 1.044517e-5
GO:0002224 toll-like receptor signaling pathway 1.059729e-5
GO:0009108 coenzyme biosynthetic process 1.086764e-5
GO:0051222 positive regulation of protein transport 1.102145e-5
GO:0032495 response to muramyl dipeptide 1.138072e-5
GO:0001822 kidney development 1.233486e-5
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 1.240774e-5
GO:0006875 cellular metal ion homeostasis 1.274490e-5
GO:0055065 metal ion homeostasis 1.296567e-5
GO:0008209 androgen metabolic process 1.308914e-5
GO:0007173 epidermal growth factor receptor signaling pathway 1.338236e-5
GO:0001910 regulation of leukocyte mediated cytotoxicity 1.377192e-5
GO:0016265 death 1.389933e-5
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 1.412421e-5
GO:0016044 cellular membrane organization 1.419179e-5
GO:0051250 negative regulation of lymphocyte activation 1.495646e-5
GO:0032494 response to peptidoglycan 1.533755e-5
GO:0014065 phosphatidylinositol 3-kinase cascade 1.548262e-5
GO:0022403 cell cycle phase 1.551244e-5
GO:0034139 regulation of toll-like receptor 3 signaling pathway 1.579924e-5
GO:0010987 negative regulation of high-density lipoprotein particle clearance 1.623577e-5
GO:0010897 negative regulation of triglyceride catabolic process 1.623577e-5
GO:0043331 response to dsRNA 1.628553e-5
GO:0009987 cellular process 1.672740e-5
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade 1.700984e-5
GO:0046883 regulation of hormone secretion 1.723839e-5
GO:0007043 cell-cell junction assembly 1.735086e-5
GO:0061024 membrane organization 1.739531e-5
GO:0070663 regulation of leukocyte proliferation 1.740346e-5
GO:0046649 lymphocyte activation 1.740470e-5
GO:0071840 cellular component organization or biogenesis 1.752115e-5
GO:0043408 regulation of MAPKKK cascade 1.770339e-5
GO:0009181 purine ribonucleoside diphosphate catabolic process 1.772441e-5
GO:0072573 tolerance induction to lipopolysaccharide 1.782266e-5
GO:2000347 positive regulation of hepatocyte proliferation 1.782266e-5
GO:2000349 negative regulation of CD40 signaling pathway 1.782266e-5
GO:0090291 negative regulation of osteoclast proliferation 1.782266e-5
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 1.782266e-5
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.782266e-5
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.782266e-5
GO:0009074 aromatic amino acid family catabolic process 1.829019e-5
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 1.836988e-5
GO:0006436 tryptophanyl-tRNA aminoacylation 1.843088e-5
GO:0032653 regulation of interleukin-10 production 1.859196e-5
GO:0008219 cell death 1.887953e-5
GO:0043623 cellular protein complex assembly 1.916920e-5
GO:0006915 apoptosis 1.976004e-5
GO:0002252 immune effector process 2.039353e-5
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 2.044632e-5
GO:0050688 regulation of defense response to virus 2.059979e-5
GO:0001101 response to acid 2.210636e-5
GO:0050852 T cell receptor signaling pathway 2.245993e-5
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 2.279341e-5
GO:0034121 regulation of toll-like receptor signaling pathway 2.294224e-5
GO:0050900 leukocyte migration 2.312570e-5
GO:2000612 regulation of thyroid-stimulating hormone secretion 2.313369e-5
GO:0007026 negative regulation of microtubule depolymerization 2.314493e-5
GO:0051056 regulation of small GTPase mediated signal transduction 2.341641e-5
GO:0012501 programmed cell death 2.401406e-5
GO:0042345 regulation of NF-kappaB import into nucleus 2.461882e-5
GO:0044419 interspecies interaction between organisms 2.657081e-5
GO:0040017 positive regulation of locomotion 2.661157e-5
GO:0060675 ureteric bud morphogenesis 2.686259e-5
GO:0008283 cell proliferation 2.703369e-5
GO:0032103 positive regulation of response to external stimulus 2.830520e-5
GO:0000087 M phase of mitotic cell cycle 2.893941e-5
GO:0031114 regulation of microtubule depolymerization 2.922905e-5
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 2.959529e-5
GO:0006486 protein glycosylation 3.043085e-5
GO:0007497 posterior midgut development 3.112612e-5
GO:0048009 insulin-like growth factor receptor signaling pathway 3.137505e-5
GO:0033036 macromolecule localization 3.150831e-5
GO:0002576 platelet degranulation 3.235675e-5
GO:0070375 BMK cascade 3.283074e-5
GO:0016050 vesicle organization 3.293958e-5
GO:0051385 response to mineralocorticoid stimulus 3.295983e-5
GO:0050853 B cell receptor signaling pathway 3.312721e-5
GO:0016198 axon choice point recognition 3.343234e-5
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway 3.402522e-5
GO:0001774 microglial cell activation 3.442429e-5
GO:0052033 pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity 3.458677e-5
GO:0040007 growth 3.478077e-5
GO:0071216 cellular response to biotic stimulus 3.638946e-5
GO:0060627 regulation of vesicle-mediated transport 3.639007e-5
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 3.780837e-5
GO:0006776 vitamin A metabolic process 3.826758e-5
GO:0031341 regulation of cell killing 3.827717e-5
GO:0022602 ovulation cycle process 3.913730e-5
GO:0050927 positive regulation of positive chemotaxis 3.971678e-5
GO:0045006 DNA deamination 4.058413e-5
GO:0010466 negative regulation of peptidase activity 4.063326e-5
GO:0042698 ovulation cycle 4.249806e-5
GO:0035411 catenin import into nucleus 4.254126e-5
GO:0072503 cellular divalent inorganic cation homeostasis 4.303782e-5
GO:0048016 inositol phosphate-mediated signaling 4.309162e-5
GO:0016079 synaptic vesicle exocytosis 4.429449e-5
GO:0006721 terpenoid metabolic process 4.617995e-5
GO:0055003 cardiac myofibril assembly 4.642701e-5
GO:0043330 response to exogenous dsRNA 4.697745e-5
GO:0051649 establishment of localization in cell 4.708031e-5
GO:0001541 ovarian follicle development 4.807968e-5
GO:0045859 regulation of protein kinase activity 4.856267e-5
GO:0043410 positive regulation of MAPKKK cascade 4.859009e-5
GO:0009629 response to gravity 4.876547e-5
GO:0044237 cellular metabolic process 4.881250e-5
GO:0034135 regulation of toll-like receptor 2 signaling pathway 4.910381e-5
GO:2000352 negative regulation of endothelial cell apoptosis 5.059111e-5
GO:0019932 second-messenger-mediated signaling 5.292765e-5
GO:0002274 myeloid leukocyte activation 5.295958e-5
GO:0071777 positive regulation of cell cycle cytokinesis 5.319155e-5
GO:0035645 enteric smooth muscle cell differentiation 5.454946e-5
GO:0007067 mitosis 5.455145e-5
GO:0070085 glycosylation 5.465444e-5
GO:0051961 negative regulation of nervous system development 5.497899e-5
GO:0048806 genitalia development 5.609110e-5
GO:0001519 peptide amidation 5.623162e-5
GO:0031622 positive regulation of fever generation 5.710009e-5
GO:0007030 Golgi organization 5.737023e-5
GO:0014732 skeletal muscle atrophy 5.743793e-5
GO:0043375 CD8-positive, alpha-beta T cell lineage commitment 5.855374e-5
GO:0032848 negative regulation of cellular pH reduction 5.855374e-5
GO:0021747 cochlear nucleus development 5.855374e-5
GO:0014042 positive regulation of neuron maturation 5.855374e-5
GO:0035771 interleukin-4-mediated signaling pathway 5.882251e-5
GO:0044356 clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine 5.944181e-5
GO:0048518 positive regulation of biological process 5.956324e-5
GO:0043900 regulation of multi-organism process 6.067562e-5
GO:0031399 regulation of protein modification process 6.075481e-5
GO:0042362 fat-soluble vitamin biosynthetic process 6.079152e-5
GO:0042116 macrophage activation 6.169883e-5
GO:0032940 secretion by cell 6.188020e-5
GO:0030335 positive regulation of cell migration 6.422098e-5
GO:0032854 positive regulation of Rap GTPase activity 6.513179e-5
GO:0043085 positive regulation of catalytic activity 6.533520e-5
GO:0050713 negative regulation of interleukin-1 beta secretion 6.552763e-5
GO:0071338 positive regulation of hair follicle cell proliferation 6.553257e-5
GO:0006678 glucosylceramide metabolic process 6.626144e-5
GO:0046620 regulation of organ growth 6.774504e-5
GO:0060271 cilium morphogenesis 6.940363e-5
GO:0046324 regulation of glucose import 6.940363e-5
GO:0071345 cellular response to cytokine stimulus 7.021552e-5
GO:0002700 regulation of production of molecular mediator of immune response 7.052273e-5
GO:0051346 negative regulation of hydrolase activity 7.069894e-5
GO:0019439 aromatic compound catabolic process 7.084865e-5
GO:0010646 regulation of cell communication 7.267718e-5
GO:0032642 regulation of chemokine production 7.301745e-5
GO:0003006 developmental process involved in reproduction 7.465315e-5
GO:0033598 mammary gland epithelial cell proliferation 7.543705e-5
GO:0051592 response to calcium ion 7.569042e-5
GO:0072278 metanephric comma-shaped body morphogenesis 7.627529e-5
GO:0043200 response to amino acid stimulus 7.739430e-5
GO:0002548 monocyte chemotaxis 7.996211e-5
GO:0072221 metanephric distal convoluted tubule development 8.209675e-5
GO:0040011 locomotion 8.295778e-5
GO:0010039 response to iron ion 8.346247e-5
GO:0050706 regulation of interleukin-1 beta secretion 8.401147e-5
GO:0006775 fat-soluble vitamin metabolic process 8.464078e-5
GO:0045786 negative regulation of cell cycle 8.479238e-5
GO:0046326 positive regulation of glucose import 8.640704e-5
GO:0048285 organelle fission 8.730215e-5
GO:0090276 regulation of peptide hormone secretion 8.810132e-5
GO:0010288 response to lead ion 8.874481e-5
GO:0001658 branching involved in ureteric bud morphogenesis 8.953283e-5
GO:0044085 cellular component biogenesis 9.116763e-5
GO:0051651 maintenance of location in cell 9.275201e-5
GO:0009750 response to fructose stimulus 9.342387e-5
GO:0010038 response to metal ion 9.412989e-5
GO:0051971 positive regulation of transmission of nerve impulse 9.418172e-5
GO:0051336 regulation of hydrolase activity 9.418594e-5
GO:0003323 type B pancreatic cell development 9.511444e-5
GO:0055080 cation homeostasis 9.513175e-5
GO:2000173 negative regulation of branching morphogenesis of a nerve 9.529104e-5
GO:0031647 regulation of protein stability 9.824340e-5
GO:0051224 negative regulation of protein transport 9.851708e-5
GO:0048731 system development 9.864455e-5
GO:0007204 elevation of cytosolic calcium ion concentration 9.910316e-5
GO:0003014 renal system process 9.949196e-5
GO:0045185 maintenance of protein location 1.009544e-4
GO:0048522 positive regulation of cellular process 1.017185e-4
GO:0051092 positive regulation of NF-kappaB transcription factor activity 1.025620e-4
GO:0007623 circadian rhythm 1.027361e-4
GO:2000097 regulation of smooth muscle cell-matrix adhesion 1.030289e-4
GO:0046639 negative regulation of alpha-beta T cell differentiation 1.035939e-4
GO:0071310 cellular response to organic substance 1.042864e-4
GO:0042990 regulation of transcription factor import into nucleus 1.047138e-4
GO:0032722 positive regulation of chemokine production 1.049692e-4
GO:0010722 regulation of ferrochelatase activity 1.055594e-4
GO:0051235 maintenance of location 1.066317e-4
GO:0043374 CD8-positive, alpha-beta T cell differentiation 1.084099e-4
GO:0032715 negative regulation of interleukin-6 production 1.086744e-4
GO:0006725 cellular aromatic compound metabolic process 1.089016e-4
GO:0015801 aromatic amino acid transport 1.096747e-4
GO:0030098 lymphocyte differentiation 1.106529e-4
GO:0002839 positive regulation of immune response to tumor cell 1.108891e-4
GO:0042572 retinol metabolic process 1.130691e-4
GO:0014866 skeletal myofibril assembly 1.138327e-4
GO:0030728 ovulation 1.146535e-4
GO:0006892 post-Golgi vesicle-mediated transport 1.159543e-4
GO:0034122 negative regulation of toll-like receptor signaling pathway 1.181048e-4
GO:0032507 maintenance of protein location in cell 1.198911e-4
GO:0051726 regulation of cell cycle 1.204086e-4
GO:0007253 cytoplasmic sequestering of NF-kappaB 1.227601e-4
GO:0001776 leukocyte homeostasis 1.235762e-4
GO:0030203 glycosaminoglycan metabolic process 1.235955e-4
GO:0072087 renal vesicle development 1.236651e-4
GO:0002260 lymphocyte homeostasis 1.248282e-4
GO:0002729 positive regulation of natural killer cell cytokine production 1.296982e-4
GO:2000147 positive regulation of cell motility 1.325227e-4
GO:0009191 ribonucleoside diphosphate catabolic process 1.343069e-4
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 1.363191e-4
GO:0051387 negative regulation of nerve growth factor receptor signaling pathway 1.388626e-4
GO:0002755 MyD88-dependent toll-like receptor signaling pathway 1.419021e-4
GO:0072283 metanephric renal vesicle morphogenesis 1.434734e-4
GO:0030538 embryonic genitalia morphogenesis 1.450139e-4
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 1.474598e-4
GO:0030003 cellular cation homeostasis 1.474945e-4
GO:0044265 cellular macromolecule catabolic process 1.476182e-4
GO:0002282 microglial cell activation involved in immune response 1.477511e-4
GO:0042110 T cell activation 1.500613e-4
GO:0033629 negative regulation of cell adhesion mediated by integrin 1.506708e-4
GO:0002827 positive regulation of T-helper 1 type immune response 1.511027e-4
GO:0001657 ureteric bud development 1.514069e-4
GO:0032652 regulation of interleukin-1 production 1.515061e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0055114 oxidation-reduction process 1.822295e-11
GO:0042180 cellular ketone metabolic process 2.325840e-11
GO:0019752 carboxylic acid metabolic process 2.360056e-11
GO:0006082 organic acid metabolic process 7.628522e-11
GO:0022414 reproductive process 2.332809e-10
GO:0000003 reproduction 3.568517e-10
GO:0044283 small molecule biosynthetic process 3.693631e-10
GO:0050860 negative regulation of T cell receptor signaling pathway 5.784780e-10
GO:0046395 carboxylic acid catabolic process 1.349689e-8
GO:0032787 monocarboxylic acid metabolic process 1.720737e-8
GO:0048378 regulation of lateral mesodermal cell fate specification 1.913882e-8
GO:0051704 multi-organism process 2.027135e-8
GO:0046394 carboxylic acid biosynthetic process 2.072374e-8
GO:0050854 regulation of antigen receptor-mediated signaling pathway 2.787175e-8
GO:0008206 bile acid metabolic process 2.917875e-8
GO:0050777 negative regulation of immune response 3.055230e-8
GO:0006629 lipid metabolic process 4.154609e-8
GO:0090329 regulation of DNA-dependent DNA replication 4.577601e-8
GO:0051013 microtubule severing 6.045849e-8
GO:0042127 regulation of cell proliferation 6.586080e-8
GO:0010033 response to organic substance 9.350758e-8
GO:0042398 cellular modified amino acid biosynthetic process 1.010327e-7
GO:0050856 regulation of T cell receptor signaling pathway 1.368229e-7
GO:0019285 glycine betaine biosynthetic process from choline 1.393415e-7
GO:0060351 cartilage development involved in endochondral bone morphogenesis 1.639708e-7
GO:0002376 immune system process 1.723254e-7
GO:2000054 negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.962529e-7
GO:0051707 response to other organism 2.246061e-7
GO:0045671 negative regulation of osteoclast differentiation 2.497001e-7
GO:0044255 cellular lipid metabolic process 2.620347e-7
GO:0001953 negative regulation of cell-matrix adhesion 2.758925e-7
GO:0002684 positive regulation of immune system process 3.142103e-7
GO:0046381 CMP-N-acetylneuraminate metabolic process 4.205179e-7
GO:0034214 protein hexamerization 4.207148e-7
GO:0009750 response to fructose stimulus 5.375000e-7
GO:0030183 B cell differentiation 5.472159e-7
GO:0001542 ovulation from ovarian follicle 5.658471e-7
GO:0072329 monocarboxylic acid catabolic process 6.196139e-7
GO:0045226 extracellular polysaccharide biosynthetic process 7.068686e-7
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration 7.185604e-7
GO:0045070 positive regulation of viral genome replication 7.453024e-7
GO:0006952 defense response 7.485694e-7
GO:0001775 cell activation 8.903193e-7
GO:0042221 response to chemical stimulus 1.011469e-6
GO:0002707 negative regulation of lymphocyte mediated immunity 1.012528e-6
GO:0051546 keratinocyte migration 1.373867e-6
GO:0006575 cellular modified amino acid metabolic process 1.405731e-6
GO:0006955 immune response 1.477683e-6
GO:2000053 regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.584990e-6
GO:0019731 antibacterial humoral response 1.629028e-6
GO:0009607 response to biotic stimulus 1.827291e-6
GO:0042448 progesterone metabolic process 2.020154e-6
GO:0008617 guanosine metabolic process 2.175103e-6
GO:0030098 lymphocyte differentiation 2.208181e-6
GO:2000104 negative regulation of DNA-dependent DNA replication 2.213168e-6
GO:0010966 regulation of phosphate transport 2.240508e-6
GO:0008652 cellular amino acid biosynthetic process 2.403416e-6
GO:0035644 phosphoanandamide dephosphorylation 2.562336e-6
GO:0018931 naphthalene metabolic process 2.822049e-6
GO:0019442 tryptophan catabolic process to acetyl-CoA 2.822049e-6
GO:0009408 response to heat 2.865451e-6
GO:0002683 negative regulation of immune system process 2.992598e-6
GO:0003417 growth plate cartilage development 3.222686e-6
GO:0050878 regulation of body fluid levels 3.636901e-6
GO:0006054 N-acetylneuraminate metabolic process 3.661441e-6
GO:0046128 purine ribonucleoside metabolic process 3.782829e-6
GO:0046649 lymphocyte activation 4.112730e-6
GO:0044281 small molecule metabolic process 4.390956e-6
GO:0007166 cell surface receptor linked signaling pathway 4.582178e-6
GO:0002521 leukocyte differentiation 4.590505e-6
GO:0022900 electron transport chain 4.734962e-6
GO:0044282 small molecule catabolic process 5.252797e-6
GO:0042278 purine nucleoside metabolic process 6.095731e-6
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development 6.213860e-6
GO:0043270 positive regulation of ion transport 6.744905e-6
GO:0046500 S-adenosylmethionine metabolic process 7.004478e-6
GO:0046689 response to mercury ion 7.007213e-6
GO:0045321 leukocyte activation 7.224174e-6
GO:0010812 negative regulation of cell-substrate adhesion 7.478602e-6
GO:0007253 cytoplasmic sequestering of NF-kappaB 7.715765e-6
GO:0050896 response to stimulus 9.459571e-6
GO:0046545 development of primary female sexual characteristics 1.060135e-5
GO:0032423 regulation of mismatch repair 1.204437e-5
GO:0006749 glutathione metabolic process 1.256741e-5
GO:0002762 negative regulation of myeloid leukocyte differentiation 1.256741e-5
GO:0055014 atrial cardiac muscle cell development 1.372617e-5
GO:0010459 negative regulation of heart rate 1.377185e-5
GO:0030728 ovulation 1.446302e-5
GO:0061181 regulation of chondrocyte development 1.498883e-5
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 1.558068e-5
GO:0006790 sulfur compound metabolic process 1.591287e-5
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 1.687006e-5
GO:0019836 hemolysis by symbiont of host erythrocytes 1.701009e-5
GO:0034644 cellular response to UV 1.730215e-5
GO:0002483 antigen processing and presentation of endogenous peptide antigen 1.841098e-5
GO:0031342 negative regulation of cell killing 1.903668e-5
GO:0050865 regulation of cell activation 2.262735e-5
GO:0000038 very long-chain fatty acid metabolic process 2.384026e-5
GO:0014743 regulation of muscle hypertrophy 2.405553e-5
GO:0007621 negative regulation of female receptivity 2.413911e-5
GO:0006116 NADH oxidation 2.413911e-5
GO:0007165 signal transduction 2.507119e-5
GO:0032876 negative regulation of DNA endoreduplication 2.565653e-5
GO:0046660 female sex differentiation 2.915721e-5
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 2.990829e-5
GO:0002694 regulation of leukocyte activation 3.004401e-5
GO:0007007 inner mitochondrial membrane organization 3.055765e-5
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 3.110747e-5
GO:0070189 kynurenine metabolic process 3.160881e-5
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 3.166685e-5
GO:0006556 S-adenosylmethionine biosynthetic process 3.304383e-5
GO:0006091 generation of precursor metabolites and energy 3.378740e-5
GO:0042113 B cell activation 3.398231e-5
GO:0008585 female gonad development 3.556675e-5
GO:0051179 localization 3.601366e-5
GO:0008202 steroid metabolic process 3.612484e-5
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 3.778106e-5
GO:0006520 cellular amino acid metabolic process 3.785605e-5
GO:0016042 lipid catabolic process 3.796263e-5
GO:0051701 interaction with host 3.807335e-5
GO:0043652 engulfment of apoptotic cell 3.829854e-5
GO:0019060 intracellular transport of viral proteins in host cell 3.842502e-5
GO:0046967 cytosol to ER transport 3.842502e-5
GO:0007618 mating 3.942415e-5
GO:0042347 negative regulation of NF-kappaB import into nucleus 4.054241e-5
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 4.084795e-5
GO:0019882 antigen processing and presentation 4.117067e-5
GO:0002238 response to molecule of fungal origin 4.331688e-5
GO:0042364 water-soluble vitamin biosynthetic process 4.442900e-5
GO:0009617 response to bacterium 4.543914e-5
GO:0042270 protection from natural killer cell mediated cytotoxicity 4.737922e-5
GO:0010611 regulation of cardiac muscle hypertrophy 4.896889e-5
GO:0070541 response to platinum ion 5.105314e-5
GO:0006950 response to stress 5.251636e-5
GO:0046129 purine ribonucleoside biosynthetic process 5.417444e-5
GO:0007608 sensory perception of smell 5.645433e-5
GO:0022415 viral reproductive process 5.771039e-5
GO:0042473 outer ear morphogenesis 6.287345e-5
GO:0007006 mitochondrial membrane organization 6.353712e-5
GO:0043502 regulation of muscle adaptation 6.526644e-5
GO:0043069 negative regulation of programmed cell death 6.660858e-5
GO:0006508 proteolysis 6.708740e-5
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 7.101217e-5
GO:0031667 response to nutrient levels 7.318107e-5
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 7.370284e-5
GO:0050680 negative regulation of epithelial cell proliferation 7.457787e-5
GO:0005996 monosaccharide metabolic process 7.494782e-5
GO:0044242 cellular lipid catabolic process 7.918011e-5
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 7.918033e-5
GO:0016032 viral reproduction 7.935796e-5
GO:0015805 S-adenosylmethionine transport 7.970681e-5
GO:0019541 propionate metabolic process 8.026795e-5
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 8.210170e-5
GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development 8.557997e-5
GO:0071394 cellular response to testosterone stimulus 8.906373e-5
GO:2000353 positive regulation of endothelial cell apoptosis 9.043642e-5
GO:0019730 antimicrobial humoral response 9.070316e-5
GO:0051716 cellular response to stimulus 9.088518e-5
GO:0043616 keratinocyte proliferation 9.428520e-5
GO:0051651 maintenance of location in cell 9.573135e-5
GO:0043066 negative regulation of apoptosis 1.007040e-4
GO:0050852 T cell receptor signaling pathway 1.047066e-4
GO:0032655 regulation of interleukin-12 production 1.053072e-4
GO:0007186 G-protein coupled receptor protein signaling pathway 1.053792e-4
GO:0006665 sphingolipid metabolic process 1.075211e-4
GO:0050873 brown fat cell differentiation 1.126988e-4
GO:0016998 cell wall macromolecule catabolic process 1.165264e-4
GO:0010817 regulation of hormone levels 1.179735e-4
GO:0009062 fatty acid catabolic process 1.186764e-4
GO:0003416 endochondral bone growth 1.196167e-4
GO:0060548 negative regulation of cell death 1.222242e-4
GO:0044403 symbiosis, encompassing mutualism through parasitism 1.276044e-4
GO:0051023 regulation of immunoglobulin secretion 1.284799e-4
GO:0006578 betaine biosynthetic process 1.332724e-4
GO:0001960 negative regulation of cytokine-mediated signaling pathway 1.368127e-4
GO:0009620 response to fungus 1.382735e-4
GO:0048609 multicellular organismal reproductive process 1.388707e-4
GO:0009071 serine family amino acid catabolic process 1.398958e-4
GO:0002820 negative regulation of adaptive immune response 1.404854e-4
GO:0045910 negative regulation of DNA recombination 1.415986e-4
GO:0050867 positive regulation of cell activation 1.453750e-4
GO:0045668 negative regulation of osteoblast differentiation 1.490434e-4
GO:0007154 cell communication 1.539149e-4
GO:0045919 positive regulation of cytolysis 1.548335e-4
GO:0032695 negative regulation of interleukin-12 production 1.579203e-4
GO:0014741 negative regulation of muscle hypertrophy 1.602239e-4
GO:0008610 lipid biosynthetic process 1.628061e-4
GO:0050708 regulation of protein secretion 1.644344e-4
GO:0051053 negative regulation of DNA metabolic process 1.659388e-4
GO:0002682 regulation of immune system process 1.759454e-4
GO:0035036 sperm-egg recognition 1.761280e-4
GO:0006212 uracil catabolic process 1.809214e-4
GO:0042753 positive regulation of circadian rhythm 1.821436e-4
GO:0019098 reproductive behavior 1.883275e-4
GO:0023052 signaling 1.895662e-4
GO:0031960 response to corticosteroid stimulus 1.957727e-4
GO:0010941 regulation of cell death 1.969779e-4
GO:0051531 NFAT protein import into nucleus 1.978201e-4
GO:0048305 immunoglobulin secretion 1.980290e-4
GO:0010751 negative regulation of nitric oxide mediated signal transduction 1.986843e-4
GO:0010754 negative regulation of cGMP-mediated signaling 1.986843e-4
GO:0010248 establishment or maintenance of transmembrane electrochemical gradient 1.986843e-4
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 1.986843e-4
GO:0007109 cytokinesis, completion of separation 1.986843e-4
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.986843e-4
GO:0051234 establishment of localization 2.064356e-4
GO:0031341 regulation of cell killing 2.184179e-4
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 2.257379e-4
GO:0051260 protein homooligomerization 2.306590e-4
GO:0031348 negative regulation of defense response 2.332519e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 2.389683e-4
GO:0051384 response to glucocorticoid stimulus 2.418537e-4
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.433781e-4
GO:0019228 regulation of action potential in neuron 2.470677e-4
GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 2.481494e-4
GO:0042594 response to starvation 2.484422e-4
GO:0002666 positive regulation of T cell tolerance induction 2.485251e-4
GO:0032074 negative regulation of nuclease activity 2.530024e-4
GO:0072539 T-helper 17 cell differentiation 2.551738e-4
GO:0006083 acetate metabolic process 2.551738e-4
GO:0002253 activation of immune response 2.622386e-4
GO:0009914 hormone transport 2.628197e-4
GO:0050778 positive regulation of immune response 2.645679e-4
GO:0045824 negative regulation of innate immune response 2.714088e-4
GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly 2.718224e-4
GO:0034097 response to cytokine stimulus 2.788502e-4
GO:0006518 peptide metabolic process 2.847798e-4
GO:0051928 positive regulation of calcium ion transport 2.864940e-4
GO:0002252 immune effector process 2.897787e-4
GO:0050907 detection of chemical stimulus involved in sensory perception 2.915163e-4
GO:0043268 positive regulation of potassium ion transport 2.937550e-4
GO:0009225 nucleotide-sugar metabolic process 3.053223e-4
GO:0002696 positive regulation of leukocyte activation 3.139448e-4
GO:0009110 vitamin biosynthetic process 3.152970e-4
GO:0006643 membrane lipid metabolic process 3.180797e-4
GO:0021847 ventricular zone neuroblast division 3.195694e-4
GO:0019543 propionate catabolic process 3.198037e-4
GO:0071482 cellular response to light stimulus 3.322972e-4
GO:0007617 mating behavior 3.413141e-4
GO:0000238 zygotene 3.462861e-4
GO:0008616 queuosine biosynthetic process 3.462861e-4
GO:0001910 regulation of leukocyte mediated cytotoxicity 3.463520e-4
GO:0007548 sex differentiation 3.507518e-4
GO:0016445 somatic diversification of immunoglobulins 3.533159e-4
GO:0050678 regulation of epithelial cell proliferation 3.553520e-4
GO:0010614 negative regulation of cardiac muscle hypertrophy 3.634285e-4
GO:0045345 positive regulation of MHC class I biosynthetic process 3.728929e-4
GO:0035881 amacrine cell differentiation 3.728929e-4
GO:0045190 isotype switching 3.815936e-4
GO:0007622 rhythmic behavior 3.853018e-4
GO:0007584 response to nutrient 3.862030e-4
GO:0048584 positive regulation of response to stimulus 4.017968e-4
GO:0031645 negative regulation of neurological system process 4.049704e-4
GO:0019853 L-ascorbic acid biosynthetic process 4.083429e-4
GO:0045577 regulation of B cell differentiation 4.288864e-4
GO:0090244 Wnt receptor signaling pathway involved in somitogenesis 4.364090e-4
GO:0032355 response to estradiol stimulus 4.402470e-4
GO:0010749 regulation of nitric oxide mediated signal transduction 4.463308e-4
GO:0070602 regulation of centromeric sister chromatid cohesion 4.502967e-4
GO:0051249 regulation of lymphocyte activation 4.508100e-4
GO:0001906 cell killing 4.524371e-4
GO:0050727 regulation of inflammatory response 4.574474e-4
GO:0043420 anthranilate metabolic process 4.578728e-4
GO:0034516 response to vitamin B6 4.578728e-4
GO:0050863 regulation of T cell activation 4.632949e-4
GO:0043266 regulation of potassium ion transport 4.657811e-4
GO:0050805 negative regulation of synaptic transmission 4.675401e-4
GO:0006810 transport 4.736708e-4
GO:0043060 meiotic metaphase I plate congression 4.766539e-4
GO:0046903 secretion 4.797339e-4
GO:2000119 negative regulation of sodium-dependent phosphate transport 5.044923e-4
GO:0048239 negative regulation of DNA recombination at telomere 5.044923e-4
GO:0006430 lysyl-tRNA aminoacylation 5.044923e-4
GO:0007063 regulation of sister chromatid cohesion 5.072839e-4
GO:0048002 antigen processing and presentation of peptide antigen 5.191109e-4
GO:0051970 negative regulation of transmission of nerve impulse 5.345693e-4
GO:0051883 killing of cells in other organism involved in symbiotic interaction 5.414980e-4
GO:2000271 positive regulation of fibroblast apoptosis 5.418285e-4
GO:2000270 negative regulation of fibroblast apoptosis 5.418285e-4
GO:0044345 stromal-epithelial cell signaling involved in prostate gland development 5.418285e-4
GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 5.418285e-4
GO:0030522 intracellular receptor mediated signaling pathway 5.454663e-4
GO:0022610 biological adhesion 5.512237e-4
GO:0071872 cellular response to epinephrine stimulus 5.579781e-4
GO:0042891 antibiotic transport 5.579781e-4
GO:0051025 negative regulation of immunoglobulin secretion 5.698877e-4
GO:0071228 cellular response to tumor cell 5.698877e-4
GO:0009116 nucleoside metabolic process 5.728564e-4
GO:0010269 response to selenium ion 5.893237e-4
GO:0071379 cellular response to prostaglandin stimulus 5.894427e-4
GO:0034374 low-density lipoprotein particle remodeling 6.057113e-4
GO:0002034 regulation of blood vessel size by renin-angiotensin 6.160050e-4
GO:0015893 drug transport 6.234901e-4
GO:0042661 regulation of mesodermal cell fate specification 6.247233e-4
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 6.255091e-4
GO:0015939 pantothenate metabolic process 6.283120e-4
GO:0002698 negative regulation of immune effector process 6.447648e-4
GO:0031640 killing of cells of other organism 6.512941e-4
GO:0002377 immunoglobulin production 6.584786e-4
GO:0006732 coenzyme metabolic process 6.685419e-4
GO:0005513 detection of calcium ion 6.748246e-4
GO:0046640 regulation of alpha-beta T cell proliferation 6.975283e-4
GO:0034104 negative regulation of tissue remodeling 6.989834e-4
GO:0050655 dermatan sulfate proteoglycan metabolic process 7.102276e-4
GO:0048512 circadian behavior 7.129302e-4
GO:0032507 maintenance of protein location in cell 7.138118e-4
GO:0071214 cellular response to abiotic stimulus 7.224035e-4
GO:0007263 nitric oxide mediated signal transduction 7.329079e-4
GO:0045137 development of primary sexual characteristics 7.341365e-4
GO:0001937 negative regulation of endothelial cell proliferation 7.465546e-4
GO:0030003 cellular cation homeostasis 7.536133e-4
GO:0071396 cellular response to lipid 7.681161e-4
GO:0042938 dipeptide transport 7.804708e-4
GO:0008615 pyridoxine biosynthetic process 7.804708e-4
GO:0034341 response to interferon-gamma 7.808651e-4
GO:0044060 regulation of endocrine process 7.882489e-4
GO:0006094 gluconeogenesis 7.900587e-4
GO:0050709 negative regulation of protein secretion 7.925669e-4
GO:0010942 positive regulation of cell death 7.966481e-4
GO:0006040 amino sugar metabolic process 8.130666e-4
GO:0009069 serine family amino acid metabolic process 8.219871e-4
GO:0030828 positive regulation of cGMP biosynthetic process 8.298479e-4
GO:0022010 central nervous system myelination 8.324040e-4
GO:0001889 liver development 8.344646e-4
GO:0006210 thymine catabolic process 8.398971e-4
GO:0050880 regulation of blood vessel size 8.668542e-4
GO:0006546 glycine catabolic process 8.794283e-4
GO:0060279 positive regulation of ovulation 8.794283e-4
GO:0021869 forebrain ventricular zone progenitor cell division 8.936898e-4
GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 9.033333e-4
GO:0002312 B cell activation involved in immune response 9.270905e-4
GO:0035150 regulation of tube size 9.334222e-4
GO:0006911 phagocytosis, engulfment 9.485038e-4
GO:0050830 defense response to Gram-positive bacterium 9.612383e-4
GO:0008207 C21-steroid hormone metabolic process 9.614826e-4
GO:0045116 protein neddylation 9.645581e-4
GO:0045087 innate immune response 9.911811e-4
GO:0006707 cholesterol catabolic process 9.980028e-4
GO:0006873 cellular ion homeostasis 1.011759e-3
GO:0008406 gonad development 1.035490e-3
GO:0016525 negative regulation of angiogenesis 1.038403e-3
GO:0007566 embryo implantation 1.056052e-3
GO:0071380 cellular response to prostaglandin E stimulus 1.057410e-3
GO:2000079 regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 1.057410e-3
GO:2000052 positive regulation of non-canonical Wnt receptor signaling pathway 1.057738e-3
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 1.064586e-3
GO:0006066 alcohol metabolic process 1.072883e-3
GO:0042759 long-chain fatty acid biosynthetic process 1.094110e-3
GO:0071496 cellular response to external stimulus 1.097533e-3
GO:0033865 nucleoside bisphosphate metabolic process 1.103795e-3
GO:0006706 steroid catabolic process 1.103795e-3
GO:0070682 proteasome regulatory particle assembly 1.108701e-3
GO:0019805 quinolinate biosynthetic process 1.108701e-3
GO:0019852 L-ascorbic acid metabolic process 1.114517e-3
GO:0016188 synaptic vesicle maturation 1.137935e-3
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 1.137935e-3
GO:0042981 regulation of apoptosis 1.153468e-3
GO:0043067 regulation of programmed cell death 1.167734e-3
GO:0043648 dicarboxylic acid metabolic process 1.205107e-3
GO:0001916 positive regulation of T cell mediated cytotoxicity 1.210299e-3
GO:0010955 negative regulation of protein processing 1.219513e-3
GO:0002443 leukocyte mediated immunity 1.224182e-3
GO:0009108 coenzyme biosynthetic process 1.226628e-3
GO:0051782 negative regulation of cell division 1.266404e-3
GO:0060452 positive regulation of cardiac muscle contraction 1.266404e-3
GO:0009309 amine biosynthetic process 1.267428e-3
GO:0044106 cellular amine metabolic process 1.277029e-3
GO:0019884 antigen processing and presentation of exogenous antigen 1.304294e-3
GO:0006916 anti-apoptosis 1.304393e-3
GO:0010757 negative regulation of plasminogen activation 1.304506e-3
GO:0007034 vacuolar transport 1.311407e-3
GO:0006631 fatty acid metabolic process 1.311586e-3
GO:0048608 reproductive structure development 1.323079e-3
GO:0060766 negative regulation of androgen receptor signaling pathway 1.325111e-3
GO:0048545 response to steroid hormone stimulus 1.331412e-3
GO:0060180 female mating behavior 1.358456e-3
GO:0002669 positive regulation of T cell anergy 1.358456e-3
GO:0019695 choline metabolic process 1.363455e-3
GO:0006954 inflammatory response 1.385517e-3
GO:0001952 regulation of cell-matrix adhesion 1.386108e-3
GO:0044262 cellular carbohydrate metabolic process 1.389013e-3
GO:0008286 insulin receptor signaling pathway 1.389942e-3
GO:0046327 glycerol biosynthetic process from pyruvate 1.407272e-3
GO:0060427 lung connective tissue development 1.407272e-3
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 1.407272e-3
GO:0030162 regulation of proteolysis 1.413606e-3
GO:0016447 somatic recombination of immunoglobulin gene segments 1.428881e-3
GO:0032354 response to follicle-stimulating hormone stimulus 1.432318e-3
GO:0045185 maintenance of protein location 1.456357e-3
GO:0006672 ceramide metabolic process 1.476336e-3
GO:0002449 lymphocyte mediated immunity 1.501905e-3
GO:0031343 positive regulation of cell killing 1.514241e-3
GO:0007155 cell adhesion 1.531390e-3
GO:0002551 mast cell chemotaxis 1.538348e-3
GO:0034605 cellular response to heat 1.542517e-3
GO:0046851 negative regulation of bone remodeling 1.552305e-3
GO:0031338 regulation of vesicle fusion 1.552305e-3
GO:0014070 response to organic cyclic compound 1.560442e-3
GO:0071877 regulation of adrenergic receptor signaling pathway 1.571673e-3
GO:0006214 thymidine catabolic process 1.571673e-3
GO:0070201 regulation of establishment of protein localization 1.578854e-3
GO:0046902 regulation of mitochondrial membrane permeability 1.594374e-3
GO:0042311 vasodilation 1.628709e-3
GO:0003018 vascular process in circulatory system 1.636455e-3
GO:0050776 regulation of immune response 1.639454e-3
GO:0046879 hormone secretion 1.677599e-3
GO:0001959 regulation of cytokine-mediated signaling pathway 1.685333e-3
GO:0051235 maintenance of location 1.703097e-3
GO:0006878 cellular copper ion homeostasis 1.720865e-3
GO:0032944 regulation of mononuclear cell proliferation 1.732089e-3
GO:0007008 outer mitochondrial membrane organization 1.733545e-3
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 1.734595e-3
GO:0006684 sphingomyelin metabolic process 1.790921e-3
GO:0019953 sexual reproduction 1.791212e-3
GO:0007589 body fluid secretion 1.797218e-3
GO:0010466 negative regulation of peptidase activity 1.826668e-3
GO:0019441 tryptophan catabolic process to kynurenine 1.839370e-3
GO:0009308 amine metabolic process 1.850568e-3
GO:0042534 regulation of tumor necrosis factor biosynthetic process 1.859300e-3
GO:0031347 regulation of defense response 1.868612e-3
GO:0061008 hepaticobiliary system development 1.870174e-3
GO:0060525 prostate glandular acinus development 1.881250e-3
GO:0006114 glycerol biosynthetic process 1.911241e-3
GO:0006145 purine base catabolic process 1.911241e-3
GO:0032980 keratinocyte activation 1.913057e-3
GO:0017144 drug metabolic process 1.955085e-3
GO:0071805 potassium ion transmembrane transport 1.970700e-3
GO:0009119 ribonucleoside metabolic process 1.979806e-3
GO:0015697 quaternary ammonium group transport 1.998215e-3
GO:0006000 fructose metabolic process 2.002986e-3
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 2.009293e-3
GO:0050670 regulation of lymphocyte proliferation 2.024227e-3
GO:0048790 maintenance of presynaptic active zone structure 2.043664e-3
GO:0055108 Golgi to transport vesicle transport 2.043664e-3
GO:0001552 ovarian follicle atresia 2.043664e-3
GO:0008285 negative regulation of cell proliferation 2.049082e-3
GO:0002757 immune response-activating signal transduction 2.069486e-3
GO:0009266 response to temperature stimulus 2.110994e-3
GO:0009063 cellular amino acid catabolic process 2.112042e-3
GO:0042245 RNA repair 2.135130e-3
GO:0046881 positive regulation of follicle-stimulating hormone secretion 2.135130e-3
GO:0002352 B cell negative selection 2.135130e-3
GO:0031117 positive regulation of microtubule depolymerization 2.136224e-3
GO:0032880 regulation of protein localization 2.150646e-3
GO:0032276 regulation of gonadotropin secretion 2.160828e-3
GO:0006568 tryptophan metabolic process 2.160828e-3
GO:0000012 single strand break repair 2.160828e-3
GO:0042035 regulation of cytokine biosynthetic process 2.163693e-3
GO:0046632 alpha-beta T cell differentiation 2.179968e-3
GO:0009267 cellular response to starvation 2.203885e-3
GO:0090361 regulation of platelet-derived growth factor production 2.224084e-3
GO:0045768 positive regulation of anti-apoptosis 2.233197e-3
GO:0046173 polyol biosynthetic process 2.236654e-3
GO:0000920 cytokinetic cell separation 2.236654e-3
GO:0015793 glycerol transport 2.256565e-3
GO:0010963 regulation of L-arginine import 2.282784e-3
GO:0051223 regulation of protein transport 2.295346e-3
GO:0001984 vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure 2.303087e-3
GO:0032781 positive regulation of ATPase activity 2.327503e-3
GO:0034553 mitochondrial respiratory chain complex II assembly 2.328566e-3
GO:0030573 bile acid catabolic process 2.328566e-3
GO:0046641 positive regulation of alpha-beta T cell proliferation 2.375140e-3
GO:0009725 response to hormone stimulus 2.380404e-3
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 2.417844e-3
GO:0007599 hemostasis 2.453483e-3
GO:0006282 regulation of DNA repair 2.454582e-3
GO:0055082 cellular chemical homeostasis 2.456249e-3
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.460540e-3
GO:0003006 developmental process involved in reproduction 2.481434e-3
GO:0021548 pons development 2.522733e-3
GO:0045767 regulation of anti-apoptosis 2.542415e-3
GO:0009056 catabolic process 2.547579e-3
GO:0051224 negative regulation of protein transport 2.556464e-3
GO:0042992 negative regulation of transcription factor import into nucleus 2.571153e-3
GO:0006635 fatty acid beta-oxidation 2.633558e-3
GO:2000050 regulation of non-canonical Wnt receptor signaling pathway 2.679327e-3
GO:0030149 sphingolipid catabolic process 2.690153e-3
GO:0010758 regulation of macrophage chemotaxis 2.690153e-3
GO:0006071 glycerol metabolic process 2.693052e-3
GO:0060759 regulation of response to cytokine stimulus 2.711084e-3
GO:0033574 response to testosterone stimulus 2.730051e-3
GO:0006720 isoprenoid metabolic process 2.730051e-3
GO:0042036 negative regulation of cytokine biosynthetic process 2.736843e-3
GO:0009991 response to extracellular stimulus 2.756264e-3
GO:0005975 carbohydrate metabolic process 2.788863e-3
GO:0051251 positive regulation of lymphocyte activation 2.793199e-3
GO:0071731 response to nitric oxide 2.807346e-3
GO:0007168 receptor guanylyl cyclase signaling pathway 2.816418e-3
GO:0070663 regulation of leukocyte proliferation 2.877107e-3
GO:0045765 regulation of angiogenesis 2.884593e-3
GO:0000712 resolution of meiotic recombination intermediates 2.887410e-3
GO:0060730 regulation of intestinal epithelial structure maintenance 2.895759e-3
GO:0035883 enteroendocrine cell differentiation 2.895759e-3
GO:0002033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure 2.895759e-3
GO:0050801 ion homeostasis 2.933555e-3
GO:0042701 progesterone secretion 2.969134e-3
GO:0071397 cellular response to cholesterol 2.981763e-3
GO:0045670 regulation of osteoclast differentiation 2.992427e-3
GO:0055070 copper ion homeostasis 3.075713e-3
GO:0051641 cellular localization 3.168129e-3