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Novel motif:25

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name:motif25_GATCCN

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0001970 positive regulation of activation of membrane attack complex 1.115581e-9
GO:0097045 phosphatidylserine exposure on blood platelet 1.313264e-9
GO:0035356 cellular triglyceride homeostasis 6.096997e-9
GO:0008588 release of cytoplasmic sequestered NF-kappaB 5.142040e-8
GO:0010890 positive regulation of sequestering of triglyceride 1.833119e-7
GO:0010625 positive regulation of Schwann cell proliferation 2.460071e-7
GO:0009301 snRNA transcription 2.574034e-7
GO:0048484 enteric nervous system development 4.480352e-7
GO:0050747 positive regulation of lipoprotein metabolic process 5.027062e-7
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 5.412328e-7
GO:0034389 lipid particle organization 5.949302e-7
GO:0001798 positive regulation of type IIa hypersensitivity 8.087111e-7
GO:0060708 spongiotrophoblast differentiation 1.074893e-6
GO:0045109 intermediate filament organization 1.377131e-6
GO:0060707 trophoblast giant cell differentiation 1.909842e-6
GO:0002502 peptide antigen assembly with MHC class I protein complex 1.932774e-6
GO:0032226 positive regulation of synaptic transmission, dopaminergic 4.931712e-6
GO:0035729 cellular response to hepatocyte growth factor stimulus 5.250283e-6
GO:0060020 Bergmann glial cell differentiation 5.760407e-6
GO:0051580 regulation of neurotransmitter uptake 6.200182e-6
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 7.885320e-6
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 7.885320e-6
GO:0010288 response to lead ion 8.496502e-6
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 9.051443e-6
GO:0010954 positive regulation of protein processing 9.629537e-6
GO:0009649 entrainment of circadian clock 1.011433e-5
GO:0031167 rRNA methylation 1.021264e-5
GO:0000725 recombinational repair 1.140259e-5
GO:0000154 rRNA modification 1.161686e-5
GO:0060706 cell differentiation involved in embryonic placenta development 1.235732e-5
GO:0006297 nucleotide-excision repair, DNA gap filling 1.264651e-5
GO:0007620 copulation 1.339233e-5
GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation 1.568774e-5
GO:0006563 L-serine metabolic process 1.843574e-5
GO:0046501 protoporphyrinogen IX metabolic process 1.956990e-5
GO:0046314 phosphocreatine biosynthetic process 1.960869e-5
GO:0042396 phosphagen biosynthetic process 2.004545e-5
GO:0048483 autonomic nervous system development 2.281693e-5
GO:0072553 terminal button organization 2.811332e-5
GO:0042168 heme metabolic process 2.882225e-5
GO:0008215 spermine metabolic process 3.353181e-5
GO:0051208 sequestering of calcium ion 3.398550e-5
GO:0003360 brainstem development 3.829434e-5
GO:0090130 tissue migration 4.399014e-5
GO:0000724 double-strand break repair via homologous recombination 4.460373e-5
GO:0046208 spermine catabolic process 4.548112e-5
GO:0060465 pharynx development 4.844469e-5
GO:0034227 tRNA thio-modification 5.080102e-5
GO:0002098 tRNA wobble uridine modification 5.080102e-5
GO:0010310 regulation of hydrogen peroxide metabolic process 5.186965e-5
GO:0006783 heme biosynthetic process 5.340893e-5
GO:0015891 siderophore transport 5.580445e-5
GO:0010002 cardioblast differentiation 6.104147e-5
GO:0008078 mesodermal cell migration 6.721755e-5
GO:0008272 sulfate transport 6.926240e-5
GO:0009313 oligosaccharide catabolic process 7.751754e-5
GO:0033693 neurofilament bundle assembly 7.862379e-5
GO:0021591 ventricular system development 9.460636e-5
GO:0021670 lateral ventricle development 9.552739e-5
GO:0090394 negative regulation of excitatory postsynaptic membrane potential 1.167828e-4
GO:0010624 regulation of Schwann cell proliferation 1.193543e-4
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity 1.201646e-4
GO:0071028 nuclear mRNA surveillance 1.369689e-4
GO:0006184 GTP catabolic process 1.462650e-4
GO:0048880 sensory system development 1.569418e-4
GO:0060712 spongiotrophoblast layer development 1.582186e-4
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 1.694917e-4
GO:0050830 defense response to Gram-positive bacterium 1.762787e-4
GO:0006596 polyamine biosynthetic process 1.845487e-4
GO:0006427 histidyl-tRNA aminoacylation 1.992960e-4
GO:0042946 glucoside transport 2.142134e-4
GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin 2.149075e-4
GO:0006598 polyamine catabolic process 2.185756e-4
GO:0048773 erythrophore differentiation 2.243966e-4
GO:0034021 response to silicon dioxide 2.243966e-4
GO:0003069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure 2.243966e-4
GO:0001315 age-dependent response to reactive oxygen species 2.243966e-4
GO:0046039 GTP metabolic process 2.370210e-4
GO:0030851 granulocyte differentiation 2.436002e-4
GO:0001941 postsynaptic membrane organization 2.610760e-4
GO:0009071 serine family amino acid catabolic process 2.726130e-4
GO:0097105 presynaptic membrane assembly 2.769311e-4
GO:0009199 ribonucleoside triphosphate metabolic process 2.786976e-4
GO:0032695 negative regulation of interleukin-12 production 2.935661e-4
GO:0009205 purine ribonucleoside triphosphate metabolic process 3.146608e-4
GO:0051497 negative regulation of stress fiber assembly 3.307555e-4
GO:0045110 intermediate filament bundle assembly 3.367569e-4
GO:0032091 negative regulation of protein binding 3.501051e-4
GO:0009144 purine nucleoside triphosphate metabolic process 3.507393e-4
GO:0045576 mast cell activation 3.654312e-4
GO:0021678 third ventricle development 3.751575e-4
GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway 3.954664e-4
GO:0010889 regulation of sequestering of triglyceride 4.138725e-4
GO:0060789 hair follicle placode formation 4.237018e-4
GO:0045837 negative regulation of membrane potential 4.294991e-4
GO:0060600 dichotomous subdivision of an epithelial terminal unit 4.297760e-4
GO:0006422 aspartyl-tRNA aminoacylation 4.341068e-4
GO:0010923 negative regulation of phosphatase activity 4.633143e-4
GO:0048841 regulation of axon extension involved in axon guidance 4.776233e-4
GO:0006473 protein acetylation 4.883540e-4
GO:0046950 cellular ketone body metabolic process 4.915404e-4
GO:0035814 negative regulation of renal sodium excretion 4.972705e-4
GO:0045792 negative regulation of cell size 5.142027e-4
GO:0006097 glyoxylate cycle 5.196043e-4
GO:0060252 positive regulation of glial cell proliferation 5.488928e-4
GO:0044258 intestinal lipid catabolic process 5.827178e-4
GO:0018350 protein esterification 5.827178e-4
GO:0015911 plasma membrane long-chain fatty acid transport 5.842582e-4
GO:0009141 nucleoside triphosphate metabolic process 5.910894e-4
GO:0010631 epithelial cell migration 6.157725e-4
GO:0001881 receptor recycling 6.325681e-4
GO:0042376 phylloquinone catabolic process 6.423137e-4
GO:0006518 peptide metabolic process 6.508766e-4
GO:0090398 cellular senescence 6.734158e-4
GO:0002885 positive regulation of hypersensitivity 6.881779e-4
GO:0090045 positive regulation of deacetylase activity 6.963705e-4
GO:0002553 histamine secretion by mast cell 7.018586e-4
GO:2000119 negative regulation of sodium-dependent phosphate transport 7.203287e-4
GO:0033159 negative regulation of protein import into nucleus, translocation 7.206643e-4
GO:0030186 melatonin metabolic process 7.206643e-4
GO:0006749 glutathione metabolic process 7.212858e-4
GO:0006844 acyl carnitine transport 7.237638e-4
GO:0010045 response to nickel ion 7.298552e-4
GO:0009107 lipoate biosynthetic process 7.298552e-4
GO:0042866 pyruvate biosynthetic process 7.499658e-4
GO:0002883 regulation of hypersensitivity 7.587108e-4
GO:0050764 regulation of phagocytosis 7.598501e-4
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 7.829474e-4
GO:0021592 fourth ventricle development 8.406402e-4
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 8.406402e-4
GO:0046952 ketone body catabolic process 8.624777e-4
GO:0051481 reduction of cytosolic calcium ion concentration 8.637529e-4
GO:0022601 menstrual cycle phase 8.827838e-4
GO:0046466 membrane lipid catabolic process 8.869368e-4
GO:0032383 regulation of intracellular cholesterol transport 9.031734e-4
GO:0019883 antigen processing and presentation of endogenous antigen 9.493988e-4
GO:0006458 'de novo' protein folding 9.549996e-4
GO:0018393 internal peptidyl-lysine acetylation 9.662912e-4
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 1.014502e-3
GO:2000009 negative regulation of protein localization at cell surface 1.014502e-3
GO:0050754 positive regulation of fractalkine biosynthetic process 1.014502e-3
GO:0050725 positive regulation of interleukin-1 beta biosynthetic process 1.014502e-3
GO:0071636 positive regulation of transforming growth factor beta production 1.053416e-3
GO:0071025 RNA surveillance 1.075918e-3
GO:0018394 peptidyl-lysine acetylation 1.091318e-3
GO:0051882 mitochondrial depolarization 1.091655e-3
GO:0043308 eosinophil degranulation 1.095519e-3
GO:0051881 regulation of mitochondrial membrane potential 1.104237e-3
GO:0010226 response to lithium ion 1.139927e-3
GO:0046521 sphingoid catabolic process 1.147413e-3
GO:0007509 mesoderm migration involved in gastrulation 1.176257e-3
GO:0051289 protein homotetramerization 1.199599e-3
GO:0001569 patterning of blood vessels 1.207750e-3
GO:0071899 negative regulation of estrogen receptor binding 1.223678e-3
GO:0060023 soft palate development 1.224969e-3
GO:0006778 porphyrin-containing compound metabolic process 1.227092e-3
GO:0019377 glycolipid catabolic process 1.273636e-3
GO:0006475 internal protein amino acid acetylation 1.293865e-3
GO:0070613 regulation of protein processing 1.363763e-3
GO:0018198 peptidyl-cysteine modification 1.368894e-3
GO:0006260 DNA replication 1.393968e-3
GO:0014002 astrocyte development 1.403712e-3
GO:0010823 negative regulation of mitochondrion organization 1.441802e-3
GO:0018119 peptidyl-cysteine S-nitrosylation 1.464371e-3
GO:0032287 peripheral nervous system myelin maintenance 1.490886e-3
GO:0032042 mitochondrial DNA metabolic process 1.512718e-3
GO:0000416 positive regulation of histone H3-K36 methylation 1.525186e-3
GO:0051084 'de novo' posttranslational protein folding 1.569767e-3
GO:0071044 histone mRNA catabolic process 1.581846e-3
GO:0043249 erythrocyte maturation 1.591549e-3
GO:0016255 attachment of GPI anchor to protein 1.612294e-3
GO:0045625 regulation of T-helper 1 cell differentiation 1.627059e-3
GO:0007249 I-kappaB kinase/NF-kappaB cascade 1.657015e-3
GO:0048012 hepatocyte growth factor receptor signaling pathway 1.726699e-3
GO:0048485 sympathetic nervous system development 1.740316e-3
GO:0006565 L-serine catabolic process 1.755055e-3
GO:0006779 porphyrin-containing compound biosynthetic process 1.822903e-3
GO:0050916 sensory perception of sweet taste 1.883198e-3
GO:0051100 negative regulation of binding 1.910576e-3
GO:0016073 snRNA metabolic process 1.919786e-3
GO:0009635 response to herbicide 1.932586e-3
GO:0048339 paraxial mesoderm development 1.941650e-3
GO:0015936 coenzyme A metabolic process 1.945293e-3
GO:0061028 establishment of endothelial barrier 1.980214e-3
GO:0007431 salivary gland development 1.989646e-3
GO:0045103 intermediate filament-based process 2.064120e-3
GO:0032225 regulation of synaptic transmission, dopaminergic 2.097291e-3
GO:0042696 menarche 2.120264e-3
GO:0030157 pancreatic juice secretion 2.138723e-3
GO:0060301 positive regulation of cytokine activity 2.173342e-3
GO:0006275 regulation of DNA replication 2.182025e-3
GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein 2.190245e-3
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 2.208202e-3
GO:0035621 ER to Golgi ceramide transport 2.208202e-3
GO:0009589 detection of UV 2.208202e-3
GO:0045081 negative regulation of interleukin-10 biosynthetic process 2.251451e-3
GO:0043000 Golgi to plasma membrane CFTR protein transport 2.269322e-3
GO:0060299 negative regulation of sarcomere organization 2.269322e-3
GO:0033292 T-tubule organization 2.269322e-3
GO:0006689 ganglioside catabolic process 2.269470e-3
GO:0030149 sphingolipid catabolic process 2.277516e-3
GO:0021636 trigeminal nerve morphogenesis 2.304634e-3
GO:0097090 presynaptic membrane organization 2.363529e-3
GO:0009142 nucleoside triphosphate biosynthetic process 2.374354e-3
GO:0070527 platelet aggregation 2.393355e-3
GO:0006261 DNA-dependent DNA replication 2.455571e-3
GO:0021782 glial cell development 2.488534e-3
GO:0042510 regulation of tyrosine phosphorylation of Stat1 protein 2.497917e-3
GO:0006399 tRNA metabolic process 2.520367e-3
GO:0009629 response to gravity 2.529304e-3
GO:0032929 negative regulation of superoxide anion generation 2.549359e-3
GO:0010693 negative regulation of alkaline phosphatase activity 2.572812e-3
GO:0002922 positive regulation of humoral immune response 2.619502e-3
GO:0007413 axonal fasciculation 2.628004e-3
GO:0035305 negative regulation of dephosphorylation 2.675223e-3
GO:0043084 penile erection 2.681484e-3
GO:0050917 sensory perception of umami taste 2.686857e-3
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 2.692714e-3
GO:0033013 tetrapyrrole metabolic process 2.720943e-3
GO:0030866 cortical actin cytoskeleton organization 2.741536e-3
GO:0090232 positive regulation of spindle checkpoint 2.754477e-3
GO:0046323 glucose import 2.794730e-3
GO:0051156 glucose 6-phosphate metabolic process 2.812712e-3
GO:0043330 response to exogenous dsRNA 2.815903e-3
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 2.818819e-3
GO:0031053 primary miRNA processing 2.826757e-3
GO:0007435 salivary gland morphogenesis 2.845964e-3
GO:0016052 carbohydrate catabolic process 2.869047e-3
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 2.881054e-3
GO:0010735 positive regulation of transcription via serum response element binding 2.894776e-3
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 2.895460e-3
GO:0006264 mitochondrial DNA replication 2.895460e-3
GO:0050935 iridophore differentiation 2.904025e-3
GO:0048937 lateral line nerve glial cell development 2.904025e-3
GO:0007009 plasma membrane organization 2.951514e-3
GO:0003334 keratinocyte development 2.971059e-3
GO:0032465 regulation of cytokinesis 2.971233e-3
GO:0046329 negative regulation of JNK cascade 3.004711e-3
GO:0008049 male courtship behavior 3.015222e-3
GO:0010734 negative regulation of protein glutathionylation 3.015222e-3
GO:0046113 nucleobase catabolic process 3.053819e-3
GO:0048242 epinephrine secretion 3.109470e-3
GO:0061196 fungiform papilla development 3.124567e-3
GO:0030194 positive regulation of blood coagulation 3.147241e-3
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway 3.151842e-3
GO:0002825 regulation of T-helper 1 type immune response 3.300941e-3
GO:0009201 ribonucleoside triphosphate biosynthetic process 3.305259e-3
GO:0060338 regulation of type I interferon-mediated signaling pathway 3.343848e-3
GO:0006595 polyamine metabolic process 3.390463e-3
GO:0070417 cellular response to cold 3.412234e-3
GO:0060154 cellular process regulating host cell cycle in response to virus 3.436053e-3
GO:0009145 purine nucleoside triphosphate biosynthetic process 3.442541e-3
GO:0030449 regulation of complement activation 3.462444e-3
GO:0043217 myelin maintenance 3.518483e-3
GO:0015862 uridine transport 3.545793e-3
GO:0003184 pulmonary valve morphogenesis 3.545793e-3
GO:0016573 histone acetylation 3.548785e-3
GO:0043647 inositol phosphate metabolic process 3.553882e-3
GO:0021629 olfactory nerve structural organization 3.557276e-3
GO:0019264 glycine biosynthetic process from serine 3.557276e-3
GO:0046931 pore complex assembly 3.591989e-3
GO:0034470 ncRNA processing 3.607886e-3
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 3.611004e-3
GO:0001667 ameboidal cell migration 3.684683e-3
GO:0060290 transdifferentiation 3.690556e-3
GO:0045581 negative regulation of T cell differentiation 3.728563e-3
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 3.818316e-3
GO:0030327 prenylated protein catabolic process 3.818316e-3
GO:0008295 spermidine biosynthetic process 3.818316e-3
GO:0050820 positive regulation of coagulation 3.822762e-3
GO:0000414 regulation of histone H3-K36 methylation 3.857764e-3
GO:2000836 positive regulation of androgen secretion 3.886547e-3
GO:2000500 positive regulation of induction of apoptosis in response to chemical stimulus 3.886547e-3
GO:0046514 ceramide catabolic process 4.017999e-3
GO:0035922 foramen ovale closure 4.035072e-3
GO:0060577 pulmonary vein morphogenesis 4.035072e-3
GO:0034241 positive regulation of macrophage fusion 4.035072e-3
GO:0042407 cristae formation 4.035072e-3
GO:0003193 pulmonary valve formation 4.035072e-3
GO:0016191 synaptic vesicle uncoating 4.035072e-3
GO:0032074 negative regulation of nuclease activity 4.035072e-3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 4.095209e-3
GO:0021784 postganglionic parasympathetic nervous system development 4.140006e-3
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 4.148266e-3
GO:0030865 cortical cytoskeleton organization 4.158411e-3
GO:0006312 mitotic recombination 4.162597e-3
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 4.229814e-3
GO:0022417 protein maturation by protein folding 4.329635e-3
GO:0030187 melatonin biosynthetic process 4.334043e-3
GO:0021993 initiation of neural tube closure 4.455530e-3
GO:0045726 positive regulation of integrin biosynthetic process 4.494571e-3
GO:0034660 ncRNA metabolic process 4.519012e-3
GO:0060263 regulation of respiratory burst 4.560198e-3
GO:0021602 cranial nerve morphogenesis 4.632913e-3
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway 4.680413e-3
GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation 4.680413e-3
GO:0060248 detection of cell density by contact stimulus involved in contact inhibition 4.680413e-3
GO:0007371 ventral midline determination 4.680413e-3
GO:0009150 purine ribonucleotide metabolic process 4.804641e-3
GO:0002712 regulation of B cell mediated immunity 4.840495e-3
GO:0046856 phosphatidylinositol dephosphorylation 4.918349e-3
GO:0015800 acidic amino acid transport 4.926890e-3
GO:0006754 ATP biosynthetic process 4.966072e-3
GO:0008347 glial cell migration 4.979206e-3
GO:0042762 regulation of sulfur metabolic process 5.004145e-3
GO:0021542 dentate gyrus development 5.021494e-3
GO:0090201 negative regulation of release of cytochrome c from mitochondria 5.034288e-3
GO:0016188 synaptic vesicle maturation 5.034288e-3
GO:0015813 L-glutamate transport 5.054564e-3
GO:0043277 apoptotic cell clearance 5.086114e-3
GO:0060300 regulation of cytokine activity 5.246973e-3
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 5.305658e-3
GO:0044070 regulation of anion transport 5.444790e-3
GO:0060040 retinal bipolar neuron differentiation 5.485592e-3
GO:0021759 globus pallidus development 5.518039e-3
GO:0071361 cellular response to ethanol 5.784538e-3
GO:0046778 modification by virus of host mRNA processing 5.915866e-3
GO:0021524 visceral motor neuron differentiation 5.915866e-3
GO:0009259 ribonucleotide metabolic process 5.916461e-3
GO:0002889 regulation of immunoglobulin mediated immune response 5.951324e-3
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 6.025238e-3
GO:0032218 riboflavin transport 6.071146e-3
GO:0007089 traversing start control point of mitotic cell cycle 6.108848e-3
GO:0051176 positive regulation of sulfur metabolic process 6.113848e-3
GO:0032429 regulation of phospholipase A2 activity 6.157734e-3
GO:0002092 positive regulation of receptor internalization 6.319096e-3
GO:0007625 grooming behavior 6.421404e-3
GO:0032876 negative regulation of DNA endoreduplication 6.444231e-3
GO:0019054 modulation by virus of host cellular process 6.502924e-3
GO:0048818 positive regulation of hair follicle maturation 6.513674e-3
GO:0042538 hyperosmotic salinity response 6.513674e-3
GO:0016139 glycoside catabolic process 6.691586e-3
GO:0061198 fungiform papilla formation 6.691586e-3
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 6.692873e-3
GO:0001510 RNA methylation 6.713222e-3
GO:0002642 positive regulation of immunoglobulin biosynthetic process 6.810648e-3
GO:0007468 regulation of rhodopsin gene expression 6.810648e-3
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 6.834320e-3
GO:0070253 somatostatin secretion 6.834320e-3
GO:0008594 photoreceptor cell morphogenesis 6.834320e-3
GO:0032812 positive regulation of epinephrine secretion 6.834320e-3
GO:0071526 semaphorin-plexin signaling pathway 6.848318e-3
GO:0032232 negative regulation of actin filament bundle assembly 6.848318e-3
GO:2000639 negative regulation of SREBP-mediated signaling pathway 6.884756e-3
GO:2000346 negative regulation of hepatocyte proliferation 6.884756e-3
GO:0060374 mast cell differentiation 6.976271e-3
GO:0070662 mast cell proliferation 6.976271e-3
GO:0014707 branchiomeric skeletal muscle development 6.976271e-3
GO:0033133 positive regulation of glucokinase activity 6.986959e-3
GO:0015991 ATP hydrolysis coupled proton transport 7.039416e-3
GO:0046782 regulation of viral transcription 7.098884e-3
GO:2001054 negative regulation of mesenchymal cell apoptosis 7.287892e-3
GO:0019242 methylglyoxal biosynthetic process 7.287892e-3
GO:0043299 leukocyte degranulation 7.293809e-3
GO:0043491 protein kinase B signaling cascade 7.299173e-3
GO:0060430 lung saccule development 7.427490e-3
GO:0048843 negative regulation of axon extension involved in axon guidance 7.439885e-3
GO:0043331 response to dsRNA 7.440568e-3
GO:0048332 mesoderm morphogenesis 7.602250e-3
GO:0001707 mesoderm formation 7.701424e-3
GO:0010727 negative regulation of hydrogen peroxide metabolic process 7.720021e-3
GO:0048147 negative regulation of fibroblast proliferation 7.755109e-3
GO:0043966 histone H3 acetylation 7.922178e-3
GO:0032957 inositol trisphosphate metabolic process 7.935817e-3
GO:0008033 tRNA processing 8.042210e-3
GO:0032922 circadian regulation of gene expression 8.147734e-3
GO:0097116 gephyrin clustering 8.313299e-3
GO:0051001 negative regulation of nitric-oxide synthase activity 8.314503e-3
GO:0048280 vesicle fusion with Golgi apparatus 8.347001e-3
GO:0001306 age-dependent response to oxidative stress 8.375022e-3
GO:0044273 sulfur compound catabolic process 8.652805e-3
GO:0048524 positive regulation of viral reproduction 8.653657e-3
GO:0034619 cellular chaperone-mediated protein complex assembly 8.758982e-3
GO:0006208 pyrimidine base catabolic process 8.777612e-3
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 8.777612e-3
GO:0050821 protein stabilization 8.812924e-3
GO:0018199 peptidyl-glutamine modification 8.836600e-3
GO:0043393 regulation of protein binding 9.056218e-3
GO:0050666 regulation of homocysteine metabolic process 9.204275e-3
GO:0016180 snRNA processing 9.356806e-3
GO:0001778 plasma membrane repair 9.532027e-3
GO:0019637 organophosphate metabolic process 9.535648e-3
GO:0045830 positive regulation of isotype switching 9.563874e-3
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 9.582312e-3
GO:0002275 myeloid cell activation involved in immune response 9.650168e-3
GO:0009207 purine ribonucleoside triphosphate catabolic process 9.669684e-3
GO:0090362 positive regulation of platelet-derived growth factor production 9.841372e-3
GO:0090271 positive regulation of fibroblast growth factor production 9.841372e-3
GO:0090336 positive regulation of brown fat cell differentiation 9.841372e-3
GO:0043543 protein acylation 9.962313e-3
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 9.993969e-3
GO:0045627 positive regulation of T-helper 1 cell differentiation 1.004416e-2
GO:0002149 hypochlorous acid biosynthetic process 1.006386e-2
GO:0006344 maintenance of chromatin silencing 1.006386e-2
GO:0045911 positive regulation of DNA recombination 1.052155e-2
GO:0001821 histamine secretion 1.068591e-2
GO:0097104 postsynaptic membrane assembly 1.070908e-2
GO:0097119 postsynaptic density protein 95 clustering 1.070908e-2
GO:0051775 response to redox state 1.074592e-2
GO:0071634 regulation of transforming growth factor beta production 1.075192e-2
GO:0009637 response to blue light 1.076308e-2
GO:0050668 positive regulation of homocysteine metabolic process 1.078431e-2
GO:0070682 proteasome regulatory particle assembly 1.078431e-2
GO:0045963 negative regulation of dopamine metabolic process 1.078431e-2
GO:0002897 positive regulation of central B cell tolerance induction 1.078431e-2
GO:0002508 central tolerance induction 1.078431e-2
GO:0071312 cellular response to alkaloid 1.085737e-2
GO:0009146 purine nucleoside triphosphate catabolic process 1.085912e-2
GO:0010042 response to manganese ion 1.095343e-2
GO:0006782 protoporphyrinogen IX biosynthetic process 1.098524e-2
GO:0070194 synaptonemal complex disassembly 1.098524e-2
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 1.098524e-2
GO:0019448 L-cysteine catabolic process 1.098524e-2
GO:0008216 spermidine metabolic process 1.098524e-2
GO:0006102 isocitrate metabolic process 1.114126e-2
GO:0045104 intermediate filament cytoskeleton organization 1.114507e-2
GO:0046687 response to chromate 1.132846e-2
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 1.132846e-2
GO:0033986 response to methanol 1.132846e-2
GO:0019369 arachidonic acid metabolic process 1.141329e-2
GO:0043089 positive regulation of Cdc42 GTPase activity 1.141895e-2
GO:0030219 megakaryocyte differentiation 1.148387e-2
GO:0007498 mesoderm development 1.163618e-2
GO:0050766 positive regulation of phagocytosis 1.171514e-2
GO:0050746 regulation of lipoprotein metabolic process 1.183702e-2
GO:0006564 L-serine biosynthetic process 1.192836e-2
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1.195134e-2
GO:0009154 purine ribonucleotide catabolic process 1.200481e-2
GO:0045872 positive regulation of rhodopsin gene expression 1.201224e-2
GO:0051102 DNA ligation involved in DNA recombination 1.201224e-2
GO:0071469 cellular response to alkalinity 1.201224e-2
GO:0046380 N-acetylneuraminate biosynthetic process 1.201224e-2
GO:0006258 UDP-glucose catabolic process 1.201224e-2
GO:0009446 putrescine biosynthetic process 1.201224e-2
GO:0035427 purine nucleoside transmembrane transport 1.201224e-2
GO:0000722 telomere maintenance via recombination 1.213103e-2
GO:0046416 D-amino acid metabolic process 1.222639e-2
GO:0009586 rhodopsin mediated phototransduction 1.224273e-2
GO:2000296 negative regulation of hydrogen peroxide catabolic process 1.225057e-2
GO:0033342 negative regulation of collagen binding 1.225057e-2
GO:0034971 histone H3-R17 methylation 1.225057e-2
GO:0042117 monocyte activation 1.247167e-2
GO:0051894 positive regulation of focal adhesion assembly 1.256345e-2
GO:0032364 oxygen homeostasis 1.279113e-2
GO:0021892 cerebral cortex GABAergic interneuron differentiation 1.290940e-2
GO:0007339 binding of sperm to zona pellucida 1.290940e-2
GO:2000334 positive regulation of blood microparticle formation 1.292823e-2
GO:0010269 response to selenium ion 1.293546e-2
GO:0046148 pigment biosynthetic process 1.302517e-2
GO:0002040 sprouting angiogenesis 1.302638e-2
GO:0009438 methylglyoxal metabolic process 1.302983e-2
GO:0030047 actin modification 1.308299e-2
GO:0032259 methylation 1.309984e-2
GO:0007253 cytoplasmic sequestering of NF-kappaB 1.322300e-2
GO:0010763 positive regulation of fibroblast migration 1.324353e-2
GO:0042074 cell migration involved in gastrulation 1.342369e-2
GO:0061136 regulation of proteasomal protein catabolic process 1.346930e-2
GO:0003032 detection of oxygen 1.348083e-2
GO:0034435 cholesterol esterification 1.349071e-2
GO:0033299 secretion of lysosomal enzymes 1.349071e-2
GO:0048842 positive regulation of axon extension involved in axon guidance 1.353467e-2
GO:0044328 canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration 1.353467e-2
GO:0044330 canonical Wnt receptor signaling pathway involved in positive regulation of wound healing 1.353467e-2
GO:0044329 canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion 1.353467e-2
GO:0033131 regulation of glucokinase activity 1.359353e-2
GO:0010107 potassium ion import 1.368647e-2
GO:0034259 negative regulation of Rho GTPase activity 1.368843e-2
GO:0022007 convergent extension involved in neural plate elongation 1.368843e-2
GO:0003085 negative regulation of systemic arterial blood pressure 1.377597e-2
GO:0001893 maternal placenta development 1.381970e-2
GO:0045471 response to ethanol 1.413765e-2
GO:0051588 regulation of neurotransmitter transport 1.418169e-2
GO:0042098 T cell proliferation 1.434347e-2
GO:0051795 positive regulation of catagen 1.441884e-2
GO:0032515 negative regulation of phosphoprotein phosphatase activity 1.462863e-2
GO:2000773 negative regulation of cellular senescence 1.468687e-2
GO:0043697 cell dedifferentiation 1.468687e-2
GO:0032916 positive regulation of transforming growth factor beta3 production 1.476523e-2
GO:0033578 protein glycosylation in Golgi 1.502864e-2
GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine 1.502864e-2
GO:0019934 cGMP-mediated signaling 1.507329e-2
GO:0006400 tRNA modification 1.515366e-2
GO:0003175 tricuspid valve development 1.518292e-2
GO:0006406 mRNA export from nucleus 1.523102e-2
GO:0048861 leukemia inhibitory factor signaling pathway 1.538863e-2
GO:0048708 astrocyte differentiation 1.547084e-2
GO:0033143 regulation of steroid hormone receptor signaling pathway 1.550679e-2
GO:0006383 transcription from RNA polymerase III promoter 1.555656e-2
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 1.559274e-2
GO:0048260 positive regulation of receptor-mediated endocytosis 1.565973e-2
GO:0031647 regulation of protein stability 1.573253e-2
GO:0016137 glycoside metabolic process 1.575639e-2
GO:0032201 telomere maintenance via semi-conservative replication 1.587336e-2
GO:0070670 response to interleukin-4 1.587982e-2
GO:0051608 histamine transport 1.590987e-2
GO:0071777 positive regulation of cell cycle cytokinesis 1.612514e-2
GO:0048846 axon extension involved in axon guidance 1.612514e-2
GO:0051028 mRNA transport 1.616248e-2
GO:0000730 DNA recombinase assembly 1.617246e-2
GO:0021660 rhombomere 3 formation 1.620230e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.716967e-8
GO:0043508 negative regulation of JUN kinase activity 2.193205e-8
GO:0048240 sperm capacitation 6.332988e-8
GO:0072132 mesenchyme morphogenesis 1.469993e-7
GO:0006476 protein deacetylation 4.173960e-7
GO:0048818 positive regulation of hair follicle maturation 4.381561e-7
GO:0061181 regulation of chondrocyte development 4.456771e-7
GO:0035601 protein deacylation 6.473867e-7
GO:0006302 double-strand break repair 7.363463e-7
GO:0051795 positive regulation of catagen 1.239897e-6
GO:0090244 Wnt receptor signaling pathway involved in somitogenesis 1.309265e-6
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 1.378382e-6
GO:0070509 calcium ion import 2.492601e-6
GO:0032915 positive regulation of transforming growth factor beta2 production 3.399641e-6
GO:0060461 right lung morphogenesis 3.440904e-6
GO:0060446 branching involved in open tracheal system development 3.440904e-6
GO:0090131 mesenchyme migration 3.440904e-6
GO:0048613 embryonic ectodermal digestive tract morphogenesis 3.440904e-6
GO:0014822 detection of wounding 3.440904e-6
GO:0048371 lateral mesodermal cell differentiation 3.440904e-6
GO:0045599 negative regulation of fat cell differentiation 3.641275e-6
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 3.644099e-6
GO:0022417 protein maturation by protein folding 3.644099e-6
GO:0060351 cartilage development involved in endochondral bone morphogenesis 3.900692e-6
GO:0051438 regulation of ubiquitin-protein ligase activity 4.524157e-6
GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 4.565237e-6
GO:0046902 regulation of mitochondrial membrane permeability 4.720657e-6
GO:0070383 DNA cytosine deamination 4.962931e-6
GO:0010529 negative regulation of transposition 4.962931e-6
GO:0016575 histone deacetylation 7.900760e-6
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 1.577273e-5
GO:0090076 relaxation of skeletal muscle 1.577273e-5
GO:0010045 response to nickel ion 1.588278e-5
GO:0014819 regulation of skeletal muscle contraction 1.624935e-5
GO:0006707 cholesterol catabolic process 1.624935e-5
GO:0034661 ncRNA catabolic process 1.706369e-5
GO:0032423 regulation of mismatch repair 1.899376e-5
GO:0090343 positive regulation of cell aging 2.099751e-5
GO:0002883 regulation of hypersensitivity 2.317543e-5
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 2.746323e-5
GO:0071214 cellular response to abiotic stimulus 2.767719e-5
GO:0003416 endochondral bone growth 2.873946e-5
GO:0008635 activation of caspase activity by cytochrome c 3.167070e-5
GO:0046514 ceramide catabolic process 4.615141e-5
GO:0032674 regulation of interleukin-5 production 4.624521e-5
GO:0060364 frontal suture morphogenesis 4.794795e-5
GO:0051561 elevation of mitochondrial calcium ion concentration 4.794795e-5
GO:2001020 regulation of response to DNA damage stimulus 5.337475e-5
GO:0071636 positive regulation of transforming growth factor beta production 5.549549e-5
GO:0060350 endochondral bone morphogenesis 5.676983e-5
GO:0070166 enamel mineralization 5.870896e-5
GO:0015931 nucleobase-containing compound transport 5.930268e-5
GO:0016139 glycoside catabolic process 6.070517e-5
GO:0051403 stress-activated MAPK cascade 6.262656e-5
GO:0090273 regulation of somatostatin secretion 6.301062e-5
GO:0045401 positive regulation of interleukin-3 biosynthetic process 6.383433e-5
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 6.383433e-5
GO:0000733 DNA strand renaturation 6.437404e-5
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 6.623773e-5
GO:0033599 regulation of mammary gland epithelial cell proliferation 7.444079e-5
GO:0035880 embryonic nail plate morphogenesis 8.065744e-5
GO:0090399 replicative senescence 8.221844e-5
GO:0006646 phosphatidylethanolamine biosynthetic process 8.577661e-5
GO:0009081 branched chain family amino acid metabolic process 8.897738e-5
GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger 9.730029e-5
GO:0001820 serotonin secretion 9.852488e-5
GO:0070602 regulation of centromeric sister chromatid cohesion 1.002766e-4
GO:0044091 membrane biogenesis 1.002766e-4
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1.042840e-4
GO:0001798 positive regulation of type IIa hypersensitivity 1.065447e-4
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 1.083174e-4
GO:0032049 cardiolipin biosynthetic process 1.083174e-4
GO:0045123 cellular extravasation 1.144707e-4
GO:0071257 cellular response to electrical stimulus 1.352307e-4
GO:0031577 spindle checkpoint 1.352307e-4
GO:0045617 negative regulation of keratinocyte differentiation 1.371490e-4
GO:0007569 cell aging 1.437827e-4
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 1.569834e-4
GO:0071218 cellular response to misfolded protein 1.721940e-4
GO:0071173 spindle assembly checkpoint 1.819378e-4
GO:0008588 release of cytoplasmic sequestered NF-kappaB 1.819378e-4
GO:0051693 actin filament capping 1.881936e-4
GO:0051923 sulfation 1.888482e-4
GO:0000413 protein peptidyl-prolyl isomerization 1.936461e-4
GO:0018230 peptidyl-L-cysteine S-palmitoylation 1.991109e-4
GO:0060154 cellular process regulating host cell cycle in response to virus 2.091156e-4
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 2.191117e-4
GO:0016032 viral reproduction 2.205635e-4
GO:0006837 serotonin transport 2.229249e-4
GO:0032469 endoplasmic reticulum calcium ion homeostasis 2.371530e-4
GO:0021535 cell migration in hindbrain 2.371530e-4
GO:0043570 maintenance of DNA repeat elements 2.434720e-4
GO:0021932 hindbrain radial glia guided cell migration 2.437915e-4
GO:0010948 negative regulation of cell cycle process 2.503108e-4
GO:0072189 ureter development 2.595215e-4
GO:0006354 transcription elongation, DNA-dependent 2.619385e-4
GO:0030157 pancreatic juice secretion 2.830654e-4
GO:0046670 positive regulation of retinal cell programmed cell death 2.858281e-4
GO:0002525 acute inflammatory response to non-antigenic stimulus 2.858281e-4
GO:0016142 O-glycoside catabolic process 2.858281e-4
GO:0060010 Sertoli cell fate commitment 2.913996e-4
GO:0002886 regulation of myeloid leukocyte mediated immunity 2.980243e-4
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 3.076496e-4
GO:0051340 regulation of ligase activity 3.079029e-4
GO:0008615 pyridoxine biosynthetic process 3.191781e-4
GO:0071174 mitotic cell cycle spindle checkpoint 3.209208e-4
GO:0032853 positive regulation of Ran GTPase activity 3.256284e-4
GO:0032383 regulation of intracellular cholesterol transport 3.256284e-4
GO:0030834 regulation of actin filament depolymerization 3.322516e-4
GO:0050658 RNA transport 3.441315e-4
GO:0021631 optic nerve morphogenesis 3.611577e-4
GO:0045198 establishment of epithelial cell apical/basal polarity 3.663187e-4
GO:0006184 GTP catabolic process 3.733839e-4
GO:0006656 phosphatidylcholine biosynthetic process 3.890915e-4
GO:0006706 steroid catabolic process 3.927812e-4
GO:0003272 endocardial cushion formation 3.936002e-4
GO:0090342 regulation of cell aging 3.962465e-4
GO:0071634 regulation of transforming growth factor beta production 3.976652e-4
GO:0006820 anion transport 3.996241e-4
GO:0008608 attachment of spindle microtubules to kinetochore 4.019722e-4
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 4.070004e-4
GO:0002885 positive regulation of hypersensitivity 4.319022e-4
GO:0090005 negative regulation of establishment of protein localization in plasma membrane 4.350055e-4
GO:0042396 phosphagen biosynthetic process 4.350055e-4
GO:0006482 protein demethylation 4.360393e-4
GO:0048014 Tie receptor signaling pathway 4.397935e-4
GO:0006513 protein monoubiquitination 4.569039e-4
GO:0002536 respiratory burst involved in inflammatory response 4.590749e-4
GO:0042772 DNA damage response, signal transduction resulting in transcription 4.704218e-4
GO:0045579 positive regulation of B cell differentiation 4.740251e-4
GO:0072133 metanephric mesenchyme morphogenesis 4.807129e-4
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 4.943770e-4
GO:0006713 glucocorticoid catabolic process 4.943770e-4
GO:0006368 transcription elongation from RNA polymerase II promoter 4.967766e-4
GO:0045869 negative regulation of retroviral genome replication 5.119286e-4
GO:0045628 regulation of T-helper 2 cell differentiation 5.121208e-4
GO:0003203 endocardial cushion morphogenesis 5.442440e-4
GO:0016236 macroautophagy 5.551645e-4
GO:0071622 regulation of granulocyte chemotaxis 5.614286e-4
GO:0032656 regulation of interleukin-13 production 5.811603e-4
GO:2000053 regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 5.819408e-4
GO:0006999 nuclear pore organization 5.819408e-4
GO:0002679 respiratory burst involved in defense response 5.868210e-4
GO:0046580 negative regulation of Ras protein signal transduction 5.942457e-4
GO:0006403 RNA localization 5.952062e-4
GO:0060326 cell chemotaxis 6.099099e-4
GO:0070059 apoptosis in response to endoplasmic reticulum stress 6.158685e-4
GO:0032048 cardiolipin metabolic process 6.540151e-4
GO:0046314 phosphocreatine biosynthetic process 6.591623e-4
GO:0051865 protein autoubiquitination 6.622881e-4
GO:0007094 mitotic cell cycle spindle assembly checkpoint 6.905904e-4
GO:0090403 oxidative stress-induced premature senescence 6.905904e-4
GO:0016574 histone ubiquitination 7.059031e-4
GO:0031281 positive regulation of cyclase activity 7.236827e-4
GO:2000001 regulation of DNA damage checkpoint 7.482999e-4
GO:0045762 positive regulation of adenylate cyclase activity 7.522192e-4
GO:0006282 regulation of DNA repair 7.812906e-4
GO:0010467 gene expression 8.112787e-4
GO:0035089 establishment of apical/basal cell polarity 8.396324e-4
GO:0016075 rRNA catabolic process 8.561798e-4
GO:0051349 positive regulation of lyase activity 8.855799e-4
GO:0001970 positive regulation of activation of membrane attack complex 8.964299e-4
GO:0042921 glucocorticoid receptor signaling pathway 9.067735e-4
GO:0050832 defense response to fungus 9.174410e-4
GO:0009303 rRNA transcription 9.280248e-4
GO:0016137 glycoside metabolic process 9.600449e-4
GO:0022900 electron transport chain 9.715499e-4
GO:0048246 macrophage chemotaxis 9.904806e-4
GO:0051058 negative regulation of small GTPase mediated signal transduction 1.038015e-3
GO:0002268 follicular dendritic cell differentiation 1.059894e-3
GO:0046373 L-arabinose metabolic process 1.064478e-3
GO:0035106 operant conditioning 1.064478e-3
GO:0038007 netrin-activated signaling pathway 1.065211e-3
GO:0032119 sequestering of zinc ion 1.065211e-3
GO:0006457 protein folding 1.070943e-3
GO:0046039 GTP metabolic process 1.073361e-3
GO:0034470 ncRNA processing 1.073465e-3
GO:0090042 tubulin deacetylation 1.085157e-3
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 1.085157e-3
GO:0007630 jump response 1.085157e-3
GO:0070846 Hsp90 deacetylation 1.085157e-3
GO:0001966 thigmotaxis 1.085157e-3
GO:0071526 semaphorin-plexin signaling pathway 1.096380e-3
GO:0014032 neural crest cell development 1.108311e-3
GO:0008637 apoptotic mitochondrial changes 1.114619e-3
GO:0006658 phosphatidylserine metabolic process 1.132564e-3
GO:0071482 cellular response to light stimulus 1.147475e-3
GO:0016072 rRNA metabolic process 1.196930e-3
GO:0001756 somitogenesis 1.222449e-3
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 1.234895e-3
GO:0032226 positive regulation of synaptic transmission, dopaminergic 1.245274e-3
GO:0010312 detoxification of zinc ion 1.245274e-3
GO:0072321 chaperone-mediated protein transport 1.251375e-3
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 1.258449e-3
GO:0048148 behavioral response to cocaine 1.258449e-3
GO:0009082 branched chain family amino acid biosynthetic process 1.258449e-3
GO:0006396 RNA processing 1.272264e-3
GO:0001969 regulation of activation of membrane attack complex 1.274360e-3
GO:0043537 negative regulation of blood vessel endothelial cell migration 1.299554e-3
GO:0043305 negative regulation of mast cell degranulation 1.308309e-3
GO:0033603 positive regulation of dopamine secretion 1.315584e-3
GO:0001682 tRNA 5'-leader removal 1.435554e-3
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 1.435554e-3
GO:0071352 cellular response to interleukin-2 1.435554e-3
GO:0016078 tRNA catabolic process 1.435554e-3
GO:0021933 radial glia guided migration of cerebellar granule cell 1.461890e-3
GO:0051444 negative regulation of ubiquitin-protein ligase activity 1.503195e-3
GO:0007190 activation of adenylate cyclase activity 1.526585e-3
GO:0006654 phosphatidic acid biosynthetic process 1.540826e-3
GO:0018208 peptidyl-proline modification 1.565009e-3
GO:0001755 neural crest cell migration 1.587769e-3
GO:0046949 fatty-acyl-CoA biosynthetic process 1.709381e-3
GO:0015706 nitrate transport 1.709381e-3
GO:0009450 gamma-aminobutyric acid catabolic process 1.709381e-3
GO:0048002 antigen processing and presentation of peptide antigen 1.717938e-3
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 1.736920e-3
GO:0021554 optic nerve development 1.752238e-3
GO:0031958 corticosteroid receptor signaling pathway 1.773446e-3
GO:0032754 positive regulation of interleukin-5 production 1.822612e-3
GO:0043525 positive regulation of neuron apoptosis 1.857255e-3
GO:0030835 negative regulation of actin filament depolymerization 1.876949e-3
GO:0043029 T cell homeostasis 1.878848e-3
GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway 1.977351e-3
GO:0042637 catagen 1.977883e-3
GO:0006515 misfolded or incompletely synthesized protein catabolic process 1.977883e-3
GO:0016577 histone demethylation 1.994963e-3
GO:0034260 negative regulation of GTPase activity 2.055558e-3
GO:0033004 negative regulation of mast cell activation 2.055558e-3
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 2.058211e-3
GO:0008208 C21-steroid hormone catabolic process 2.058211e-3
GO:0021997 neural plate axis specification 2.066938e-3
GO:0033160 positive regulation of protein import into nucleus, translocation 2.073439e-3
GO:0042254 ribosome biogenesis 2.081426e-3
GO:0015711 organic anion transport 2.085295e-3
GO:0032696 negative regulation of interleukin-13 production 2.109885e-3
GO:0018199 peptidyl-glutamine modification 2.172094e-3
GO:0003417 growth plate cartilage development 2.172881e-3
GO:0001788 antibody-dependent cellular cytotoxicity 2.188333e-3
GO:0046502 uroporphyrinogen III metabolic process 2.188333e-3
GO:0042733 embryonic digit morphogenesis 2.299433e-3
GO:0045006 DNA deamination 2.305091e-3
GO:0002572 pro-T cell differentiation 2.305091e-3
GO:0070189 kynurenine metabolic process 2.345076e-3
GO:0001569 patterning of blood vessels 2.359702e-3
GO:0010954 positive regulation of protein processing 2.412413e-3
GO:0006555 methionine metabolic process 2.508922e-3
GO:0030837 negative regulation of actin filament polymerization 2.515333e-3
GO:0006839 mitochondrial transport 2.520260e-3
GO:0060221 retinal rod cell differentiation 2.521104e-3
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 2.521104e-3
GO:0046474 glycerophospholipid biosynthetic process 2.552519e-3
GO:0045761 regulation of adenylate cyclase activity 2.556947e-3
GO:0043623 cellular protein complex assembly 2.557011e-3
GO:0015813 L-glutamate transport 2.558421e-3
GO:0007521 muscle cell fate determination 2.561172e-3
GO:0050999 regulation of nitric-oxide synthase activity 2.588092e-3
GO:0030917 midbrain-hindbrain boundary development 2.619163e-3
GO:0051028 mRNA transport 2.635783e-3
GO:0048050 post-embryonic eye morphogenesis 2.642610e-3
GO:0061035 regulation of cartilage development 2.697951e-3
GO:0060349 bone morphogenesis 2.707483e-3
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 2.712328e-3
GO:0002027 regulation of heart rate 2.715064e-3
GO:0034644 cellular response to UV 2.769473e-3
GO:0021943 formation of radial glial scaffolds 2.792439e-3
GO:0030851 granulocyte differentiation 2.868272e-3
GO:0061298 retina vasculature development in camera-type eye 2.872360e-3
GO:0018202 peptidyl-histidine modification 2.936064e-3
GO:0060547 negative regulation of necrotic cell death 2.947674e-3
GO:0019054 modulation by virus of host cellular process 2.984878e-3
GO:0002326 B cell lineage commitment 2.984878e-3
GO:0007638 mechanosensory behavior 3.049774e-3
GO:0071353 cellular response to interleukin-4 3.054885e-3
GO:0009083 branched chain family amino acid catabolic process 3.056772e-3
GO:0006659 phosphatidylserine biosynthetic process 3.069817e-3
GO:0034641 cellular nitrogen compound metabolic process 3.091157e-3
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 3.102017e-3
GO:0061312 BMP signaling pathway involved in heart development 3.102017e-3
GO:0048145 regulation of fibroblast proliferation 3.114776e-3
GO:0070842 aggresome assembly 3.146742e-3
GO:0030210 heparin biosynthetic process 3.146742e-3
GO:0051255 spindle midzone assembly 3.146742e-3
GO:0048368 lateral mesoderm development 3.218260e-3
GO:0000045 autophagic vacuole assembly 3.287316e-3
GO:0016070 RNA metabolic process 3.406744e-3
GO:0010518 positive regulation of phospholipase activity 3.410582e-3
GO:0032736 positive regulation of interleukin-13 production 3.421996e-3
GO:2000297 negative regulation of synapse maturation 3.424941e-3
GO:0014033 neural crest cell differentiation 3.471657e-3
GO:2000054 negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 3.482993e-3
GO:0006477 protein sulfation 3.496690e-3
GO:0030258 lipid modification 3.513102e-3
GO:0031279 regulation of cyclase activity 3.520220e-3
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 3.537046e-3
GO:0030593 neutrophil chemotaxis 3.537046e-3
GO:0010824 regulation of centrosome duplication 3.552970e-3
GO:0045989 positive regulation of striated muscle contraction 3.565664e-3
GO:0009086 methionine biosynthetic process 3.592567e-3
GO:0032714 negative regulation of interleukin-5 production 3.594864e-3
GO:0060997 dendritic spine morphogenesis 3.617137e-3
GO:0042823 pyridoxal phosphate biosynthetic process 3.621418e-3
GO:0051238 sequestering of metal ion 3.634919e-3
GO:0006370 mRNA capping 3.634919e-3
GO:0007202 activation of phospholipase C activity 3.638674e-3
GO:0006366 transcription from RNA polymerase II promoter 3.644313e-3
GO:0006779 porphyrin-containing compound biosynthetic process 3.645408e-3
GO:0002524 hypersensitivity 3.656322e-3
GO:0043304 regulation of mast cell degranulation 3.691081e-3
GO:0006913 nucleocytoplasmic transport 3.696670e-3
GO:0002309 T cell proliferation involved in immune response 3.818992e-3
GO:0060363 cranial suture morphogenesis 3.921835e-3
GO:0060019 radial glial cell differentiation 3.932637e-3
GO:0010718 positive regulation of epithelial to mesenchymal transition 3.937574e-3
GO:0051339 regulation of lyase activity 3.948927e-3
GO:0045091 regulation of retroviral genome replication 3.966704e-3
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 4.058242e-3
GO:0070584 mitochondrion morphogenesis 4.109960e-3
GO:0002149 hypochlorous acid biosynthetic process 4.113051e-3
GO:0034111 negative regulation of homotypic cell-cell adhesion 4.113051e-3
GO:0031161 phosphatidylinositol catabolic process 4.210367e-3
GO:0016140 O-glycoside metabolic process 4.210367e-3
GO:0001811 negative regulation of type I hypersensitivity 4.210367e-3
GO:0002638 negative regulation of immunoglobulin production 4.210367e-3
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 4.220536e-3
GO:0002861 regulation of inflammatory response to antigenic stimulus 4.223939e-3
GO:0061304 retinal blood vessel morphogenesis 4.249542e-3
GO:0035411 catenin import into nucleus 4.310951e-3
GO:0006599 phosphagen metabolic process 4.310951e-3
GO:0070613 regulation of protein processing 4.381578e-3
GO:0050792 regulation of viral reproduction 4.417630e-3
GO:0060591 chondroblast differentiation 4.532126e-3
GO:0021903 rostrocaudal neural tube patterning 4.535588e-3
GO:0051443 positive regulation of ubiquitin-protein ligase activity 4.603474e-3
GO:0008033 tRNA processing 4.629983e-3
GO:0048144 fibroblast proliferation 4.635959e-3
GO:0035645 enteric smooth muscle cell differentiation 4.635959e-3
GO:0002024 diet induced thermogenesis 4.635959e-3
GO:0007497 posterior midgut development 4.635959e-3
GO:0032094 response to food 4.679877e-3
GO:0030865 cortical cytoskeleton organization 4.831646e-3
GO:0032910 regulation of transforming growth factor beta3 production 4.892393e-3
GO:0021532 neural tube patterning 4.931241e-3
GO:0048147 negative regulation of fibroblast proliferation 5.025011e-3
GO:0045624 positive regulation of T-helper cell differentiation 5.047706e-3
GO:0043923 positive regulation by host of viral transcription 5.087179e-3
GO:0001504 neurotransmitter uptake 5.093634e-3
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 5.104206e-3
GO:2000078 positive regulation of type B pancreatic cell development 5.188802e-3
GO:0060710 chorio-allantoic fusion 5.212911e-3
GO:0060674 placenta blood vessel development 5.263402e-3
GO:0003148 outflow tract septum morphogenesis 5.387562e-3
GO:0090003 regulation of establishment of protein localization in plasma membrane 5.427456e-3
GO:0007406 negative regulation of neuroblast proliferation 5.442626e-3
GO:0070933 histone H4 deacetylation 5.447542e-3
GO:0014031 mesenchymal cell development 5.480499e-3
GO:0048820 hair follicle maturation 5.581845e-3
GO:0006364 rRNA processing 5.584752e-3
GO:0030223 neutrophil differentiation 5.650396e-3
GO:0072208 metanephric smooth muscle tissue development 5.664002e-3
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 5.664002e-3
GO:0072259 metanephric interstitial cell development 5.664002e-3
GO:0072184 renal vesicle progenitor cell differentiation 5.664002e-3
GO:0072169 specification of posterior mesonephric tubule identity 5.664002e-3
GO:0072168 specification of anterior mesonephric tubule identity 5.664002e-3
GO:0046092 deoxycytidine metabolic process 5.696667e-3
GO:0016557 peroxisome membrane biogenesis 5.696667e-3
GO:0032608 interferon-beta production 5.696667e-3
GO:0043084 penile erection 5.719360e-3
GO:0009826 unidimensional cell growth 5.719360e-3
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 5.719360e-3
GO:0045605 negative regulation of epidermal cell differentiation 5.750589e-3
GO:0007006 mitochondrial membrane organization 5.754295e-3
GO:0007127 meiosis I 5.765177e-3
GO:0000239 pachytene 5.826337e-3
GO:0030149 sphingolipid catabolic process 5.834819e-3
GO:0045581 negative regulation of T cell differentiation 5.856386e-3
GO:0051169 nuclear transport 5.857844e-3
GO:0045017 glycerolipid biosynthetic process 5.878151e-3
GO:0006139 nucleobase-containing compound metabolic process 5.921776e-3
GO:0070228 regulation of lymphocyte apoptosis 5.941676e-3
GO:0007128 meiotic prophase I 5.947612e-3
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 5.983779e-3
GO:0032272 negative regulation of protein polymerization 5.999047e-3
GO:0010157 response to chlorate 6.068971e-3
GO:0043277 apoptotic cell clearance 6.071076e-3
GO:0001836 release of cytochrome c from mitochondria 6.117271e-3
GO:0072553 terminal button organization 6.147279e-3
GO:0034509 centromeric core chromatin assembly 6.147279e-3
GO:0034080 CenH3-containing nucleosome assembly at centromere 6.147279e-3
GO:0042450 arginine biosynthetic process via ornithine 6.166139e-3
GO:0071624 positive regulation of granulocyte chemotaxis 6.166139e-3
GO:0019676 ammonia assimilation cycle 6.166139e-3
GO:0018125 peptidyl-cysteine methylation 6.166139e-3
GO:0021592 fourth ventricle development 6.200842e-3
GO:0019987 negative regulation of anti-apoptosis 6.200842e-3
GO:0090304 nucleic acid metabolic process 6.362330e-3
GO:0045630 positive regulation of T-helper 2 cell differentiation 6.381741e-3
GO:0021861 forebrain radial glial cell differentiation 6.411541e-3
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 6.507290e-3
GO:0021853 cerebral cortex GABAergic interneuron migration 6.729394e-3
GO:0070243 regulation of thymocyte apoptosis 6.814463e-3
GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 6.854286e-3
GO:0007632 visual behavior 6.938374e-3
GO:0045793 positive regulation of cell size 6.940685e-3
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 6.941608e-3
GO:0043366 beta selection 6.941608e-3
GO:0006281 DNA repair 7.128959e-3
GO:0022415 viral reproductive process 7.230299e-3
GO:0051798 positive regulation of hair follicle development 7.256173e-3
GO:0048013 ephrin receptor signaling pathway 7.322229e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 7.366609e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 7.373783e-3
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 7.380547e-3
GO:0043048 dolichyl monophosphate biosynthetic process 7.476687e-3
GO:0060699 regulation of endoribonuclease activity 7.476687e-3
GO:0000056 ribosomal small subunit export from nucleus 7.476687e-3
GO:0018960 4-nitrophenol metabolic process 7.476687e-3
GO:0000055 ribosomal large subunit export from nucleus 7.476687e-3
GO:0045046 protein import into peroxisome membrane 7.590236e-3
GO:0006438 valyl-tRNA aminoacylation 7.590236e-3
GO:0006551 leucine metabolic process 7.590236e-3
GO:0032330 regulation of chondrocyte differentiation 7.822161e-3
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 7.952831e-3
GO:0032689 negative regulation of interferon-gamma production 8.017275e-3
GO:2000191 regulation of fatty acid transport 8.017275e-3
GO:0045764 positive regulation of cellular amino acid metabolic process 8.075118e-3
GO:0072289 metanephric nephron tubule formation 8.075118e-3
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 8.075118e-3
GO:0006983 ER overload response 8.107613e-3
GO:0034764 positive regulation of transmembrane transport 8.249801e-3
GO:0031034 myosin filament assembly 8.273890e-3
GO:0008380 RNA splicing 8.325875e-3
GO:0002828 regulation of type 2 immune response 8.353966e-3
GO:0048069 eye pigmentation 8.461583e-3
GO:0060244 negative regulation of cell proliferation involved in contact inhibition 8.580410e-3
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 8.580410e-3
GO:0006807 nitrogen compound metabolic process 8.587404e-3
GO:0045598 regulation of fat cell differentiation 8.729685e-3
GO:0019882 antigen processing and presentation 8.780351e-3
GO:0060561 apoptosis involved in morphogenesis 8.864221e-3
GO:0006171 cAMP biosynthetic process 8.885919e-3
GO:0033205 cell cycle cytokinesis 8.896976e-3
GO:0019395 fatty acid oxidation 8.908421e-3
GO:0002331 pre-B cell allelic exclusion 8.975440e-3
GO:0051938 L-glutamate import 9.151167e-3
GO:0015800 acidic amino acid transport 9.213509e-3
GO:0060458 right lung development 9.243225e-3
GO:0042713 sperm ejaculation 9.243225e-3
GO:0090150 establishment of protein localization in membrane 9.310003e-3
GO:0021678 third ventricle development 9.310003e-3
GO:0035815 positive regulation of renal sodium excretion 9.310003e-3
GO:0003002 regionalization 9.372084e-3
GO:0010759 positive regulation of macrophage chemotaxis 9.418063e-3
GO:0090324 negative regulation of oxidative phosphorylation 9.419051e-3
GO:0010255 glucose mediated signaling pathway 9.419051e-3
GO:0006780 uroporphyrinogen III biosynthetic process 9.419051e-3
GO:0043921 modulation by host of viral transcription 9.461316e-3
GO:0035272 exocrine system development 9.473343e-3
GO:0044319 wound healing, spreading of cells 9.495094e-3
GO:0031507 heterochromatin formation 9.495094e-3
GO:2000639 negative regulation of SREBP-mediated signaling pathway 9.518427e-3
GO:0018343 protein farnesylation 9.518427e-3
GO:2000346 negative regulation of hepatocyte proliferation 9.518427e-3
GO:0042307 positive regulation of protein import into nucleus 9.642673e-3
GO:0017144 drug metabolic process 9.685640e-3
GO:0043967 histone H4 acetylation 9.827499e-3
GO:0048708 astrocyte differentiation 9.905714e-3
GO:0006778 porphyrin-containing compound metabolic process 9.905714e-3
GO:0051298 centrosome duplication 9.952754e-3
GO:0021798 forebrain dorsal/ventral pattern formation 1.011146e-2
GO:0009952 anterior/posterior pattern specification 1.016657e-2
GO:0006573 valine metabolic process 1.030216e-2
GO:0060438 trachea development 1.038767e-2
GO:0043163 cell envelope organization 1.040955e-2
GO:0030449 regulation of complement activation 1.047998e-2
GO:0009314 response to radiation 1.057604e-2
GO:0000281 cytokinesis after mitosis 1.058547e-2
GO:0014829 vascular smooth muscle contraction 1.073667e-2
GO:0002884 negative regulation of hypersensitivity 1.076416e-2
GO:0009309 amine biosynthetic process 1.089755e-2
GO:0033013 tetrapyrrole metabolic process 1.104384e-2
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1.115257e-2
GO:0030902 hindbrain development 1.122343e-2
GO:0035313 wound healing, spreading of epidermal cells 1.145195e-2
GO:0051016 barbed-end actin filament capping 1.158574e-2
GO:0046718 entry of virus into host cell 1.158574e-2
GO:0060445 branching involved in salivary gland morphogenesis 1.164432e-2
GO:0072676 lymphocyte migration 1.169571e-2
GO:0060486 Clara cell differentiation 1.178203e-2
GO:0016064 immunoglobulin mediated immune response 1.181007e-2
GO:0071478 cellular response to radiation 1.181437e-2
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway 1.190270e-2
GO:0070925 organelle assembly 1.191182e-2
GO:0010863 positive regulation of phospholipase C activity 1.194103e-2
GO:0009207 purine ribonucleoside triphosphate catabolic process 1.206473e-2
GO:0010332 response to gamma radiation 1.221277e-2
GO:0010763 positive regulation of fibroblast migration 1.230657e-2
GO:0008535 respiratory chain complex IV assembly 1.230964e-2
GO:0060008 Sertoli cell differentiation 1.234879e-2
GO:0009146 purine nucleoside triphosphate catabolic process 1.244635e-2