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Novel motif:27

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name:motif27_CCTGCA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0043462 regulation of ATPase activity 2.348151e-14
GO:0045321 leukocyte activation 5.380176e-12
GO:0042110 T cell activation 3.696196e-11
GO:0002149 hypochlorous acid biosynthetic process 1.554332e-10
GO:0072376 protein activation cascade 2.592249e-10
GO:0007522 visceral muscle development 1.718101e-9
GO:0050728 negative regulation of inflammatory response 3.011636e-9
GO:0046655 folic acid metabolic process 5.082912e-9
GO:0045104 intermediate filament cytoskeleton organization 5.464915e-9
GO:0046649 lymphocyte activation 6.234167e-9
GO:0002679 respiratory burst involved in defense response 7.546112e-9
GO:0034762 regulation of transmembrane transport 8.432219e-9
GO:0006956 complement activation 8.626217e-9
GO:0006545 glycine biosynthetic process 1.010643e-8
GO:0051917 regulation of fibrinolysis 1.213215e-8
GO:0045103 intermediate filament-based process 1.289789e-8
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 1.319782e-8
GO:0050832 defense response to fungus 1.565295e-8
GO:0006544 glycine metabolic process 1.848921e-8
GO:0003009 skeletal muscle contraction 2.331589e-8
GO:0061041 regulation of wound healing 2.368799e-8
GO:0002604 regulation of dendritic cell antigen processing and presentation 2.422962e-8
GO:0046724 oxalic acid secretion 3.086503e-8
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 3.086503e-8
GO:0044258 intestinal lipid catabolic process 3.355298e-8
GO:0018350 protein esterification 3.355298e-8
GO:0002577 regulation of antigen processing and presentation 3.609898e-8
GO:0032796 uropod organization 4.145491e-8
GO:0060037 pharyngeal system development 4.234614e-8
GO:0002455 humoral immune response mediated by circulating immunoglobulin 4.322717e-8
GO:0006692 prostanoid metabolic process 4.384617e-8
GO:0009620 response to fungus 4.862952e-8
GO:0032715 negative regulation of interleukin-6 production 4.936645e-8
GO:0035691 macrophage migration inhibitory factor signaling pathway 6.392083e-8
GO:0090130 tissue migration 6.401878e-8
GO:0050821 protein stabilization 6.680658e-8
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 7.101046e-8
GO:0006958 complement activation, classical pathway 7.148450e-8
GO:0055009 atrial cardiac muscle tissue morphogenesis 8.124191e-8
GO:0051918 negative regulation of fibrinolysis 9.505968e-8
GO:0044130 negative regulation of growth of symbiont in host 9.869380e-8
GO:0001775 cell activation 9.973316e-8
GO:0016601 Rac protein signal transduction 1.103026e-7
GO:0019724 B cell mediated immunity 1.242077e-7
GO:0006979 response to oxidative stress 1.270688e-7
GO:0050678 regulation of epithelial cell proliferation 1.404229e-7
GO:0032101 regulation of response to external stimulus 1.623842e-7
GO:0043249 erythrocyte maturation 1.627562e-7
GO:0042415 norepinephrine metabolic process 1.727854e-7
GO:0043901 negative regulation of multi-organism process 1.997708e-7
GO:0051234 establishment of localization 2.091928e-7
GO:0006760 folic acid-containing compound metabolic process 2.131472e-7
GO:0006952 defense response 2.484845e-7
GO:0002902 regulation of B cell apoptosis 2.491094e-7
GO:0060300 regulation of cytokine activity 2.671416e-7
GO:0031348 negative regulation of defense response 3.104723e-7
GO:0003229 ventricular cardiac muscle tissue development 3.649890e-7
GO:0070301 cellular response to hydrogen peroxide 3.806347e-7
GO:0008016 regulation of heart contraction 3.923026e-7
GO:0051764 actin crosslink formation 4.513450e-7
GO:0030193 regulation of blood coagulation 4.539607e-7
GO:0043368 positive T cell selection 4.864470e-7
GO:0006811 ion transport 5.124739e-7
GO:0006909 phagocytosis 5.499731e-7
GO:0008203 cholesterol metabolic process 5.651054e-7
GO:0006548 histidine catabolic process 5.671186e-7
GO:0000212 meiotic spindle organization 5.760825e-7
GO:0002443 leukocyte mediated immunity 5.766906e-7
GO:0006810 transport 5.874189e-7
GO:0022406 membrane docking 6.003020e-7
GO:0030100 regulation of endocytosis 6.702512e-7
GO:0046456 icosanoid biosynthetic process 7.472407e-7
GO:0001836 release of cytochrome c from mitochondria 7.992603e-7
GO:0016125 sterol metabolic process 8.269985e-7
GO:0090344 negative regulation of cell aging 8.830393e-7
GO:0006707 cholesterol catabolic process 9.082481e-7
GO:0034765 regulation of ion transmembrane transport 9.625839e-7
GO:0006959 humoral immune response 1.014608e-6
GO:0035814 negative regulation of renal sodium excretion 1.039104e-6
GO:0002449 lymphocyte mediated immunity 1.132037e-6
GO:0051693 actin filament capping 1.143434e-6
GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.202169e-6
GO:0010310 regulation of hydrogen peroxide metabolic process 1.271461e-6
GO:0016064 immunoglobulin mediated immune response 1.282778e-6
GO:0002026 regulation of the force of heart contraction 1.338066e-6
GO:0006821 chloride transport 1.349103e-6
GO:0060301 positive regulation of cytokine activity 1.368107e-6
GO:0055010 ventricular cardiac muscle tissue morphogenesis 1.389013e-6
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 1.488755e-6
GO:0008078 mesodermal cell migration 1.500420e-6
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1.537155e-6
GO:0000302 response to reactive oxygen species 1.589957e-6
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 1.616321e-6
GO:0002252 immune effector process 1.828074e-6
GO:0006636 unsaturated fatty acid biosynthetic process 1.830421e-6
GO:0003180 aortic valve morphogenesis 1.984101e-6
GO:0050727 regulation of inflammatory response 2.056830e-6
GO:0003208 cardiac ventricle morphogenesis 2.211181e-6
GO:0035089 establishment of apical/basal cell polarity 2.315840e-6
GO:0031295 T cell costimulation 2.384773e-6
GO:0033326 cerebrospinal fluid secretion 2.514954e-6
GO:0043269 regulation of ion transport 2.653537e-6
GO:0015874 norepinephrine transport 2.692711e-6
GO:0072268 pattern specification involved in metanephros development 3.018391e-6
GO:0032680 regulation of tumor necrosis factor production 3.196382e-6
GO:0034220 ion transmembrane transport 3.204755e-6
GO:0001546 preantral ovarian follicle growth 3.478487e-6
GO:0051932 synaptic transmission, GABAergic 3.478487e-6
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.556583e-6
GO:0048144 fibroblast proliferation 3.790125e-6
GO:0001880 Mullerian duct regression 3.790125e-6
GO:0045575 basophil activation 3.996195e-6
GO:0021570 rhombomere 4 development 3.996195e-6
GO:0001694 histamine biosynthetic process 3.996195e-6
GO:0006955 immune response 4.410768e-6
GO:0030195 negative regulation of blood coagulation 4.466518e-6
GO:0032695 negative regulation of interleukin-12 production 4.496802e-6
GO:0051298 centrosome duplication 5.041468e-6
GO:0032914 positive regulation of transforming growth factor beta1 production 5.239612e-6
GO:0001937 negative regulation of endothelial cell proliferation 5.325197e-6
GO:0051346 negative regulation of hydrolase activity 5.562885e-6
GO:0030835 negative regulation of actin filament depolymerization 5.817582e-6
GO:0051179 localization 6.214374e-6
GO:0002093 auditory receptor cell morphogenesis 6.812802e-6
GO:0021526 medial motor column neuron differentiation 7.373481e-6
GO:0051488 activation of anaphase-promoting complex activity 7.642860e-6
GO:0071392 cellular response to estradiol stimulus 8.261592e-6
GO:0032720 negative regulation of tumor necrosis factor production 9.817000e-6
GO:0006633 fatty acid biosynthetic process 9.942355e-6
GO:0030157 pancreatic juice secretion 1.039862e-5
GO:0051220 cytoplasmic sequestering of protein 1.045504e-5
GO:0007155 cell adhesion 1.055189e-5
GO:0048243 norepinephrine secretion 1.081050e-5
GO:0006690 icosanoid metabolic process 1.106853e-5
GO:0034551 mitochondrial respiratory chain complex III assembly 1.107043e-5
GO:0010535 positive regulation of activation of JAK2 kinase activity 1.138110e-5
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 1.149971e-5
GO:0071805 potassium ion transmembrane transport 1.157863e-5
GO:0002903 negative regulation of B cell apoptosis 1.182564e-5
GO:0072593 reactive oxygen species metabolic process 1.192226e-5
GO:0050881 musculoskeletal movement 1.221583e-5
GO:0048278 vesicle docking 1.234087e-5
GO:0051293 establishment of spindle localization 1.251794e-5
GO:0000060 protein import into nucleus, translocation 1.253556e-5
GO:0051533 positive regulation of NFAT protein import into nucleus 1.354286e-5
GO:0009144 purine nucleoside triphosphate metabolic process 1.376787e-5
GO:0002367 cytokine production involved in immune response 1.419145e-5
GO:0045414 regulation of interleukin-8 biosynthetic process 1.461640e-5
GO:0045058 T cell selection 1.462262e-5
GO:0045668 negative regulation of osteoblast differentiation 1.513870e-5
GO:0042363 fat-soluble vitamin catabolic process 1.616253e-5
GO:0042744 hydrogen peroxide catabolic process 1.618413e-5
GO:0055085 transmembrane transport 1.637212e-5
GO:0002250 adaptive immune response 1.738820e-5
GO:0007586 digestion 1.763606e-5
GO:0019226 transmission of nerve impulse 1.801895e-5
GO:0071636 positive regulation of transforming growth factor beta production 1.901329e-5
GO:0009205 purine ribonucleoside triphosphate metabolic process 1.901798e-5
GO:0016056 rhodopsin mediated signaling pathway 1.905930e-5
GO:0070727 cellular macromolecule localization 1.946829e-5
GO:0044057 regulation of system process 1.969223e-5
GO:0033559 unsaturated fatty acid metabolic process 2.083302e-5
GO:0032102 negative regulation of response to external stimulus 2.091959e-5
GO:0021548 pons development 2.101655e-5
GO:0009070 serine family amino acid biosynthetic process 2.105341e-5
GO:0007386 compartment pattern specification 2.122464e-5
GO:0002019 regulation of renal output by angiotensin 2.172671e-5
GO:0010754 negative regulation of cGMP-mediated signaling 2.174169e-5
GO:0043652 engulfment of apoptotic cell 2.174169e-5
GO:0010751 negative regulation of nitric oxide mediated signal transduction 2.174169e-5
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 2.174169e-5
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.174169e-5
GO:0045059 positive thymic T cell selection 2.207231e-5
GO:0051323 metaphase 2.318454e-5
GO:0032972 regulation of muscle filament sliding speed 2.321737e-5
GO:0042534 regulation of tumor necrosis factor biosynthetic process 2.350614e-5
GO:0042491 auditory receptor cell differentiation 2.460248e-5
GO:0060337 type I interferon-mediated signaling pathway 2.547120e-5
GO:0009720 detection of hormone stimulus 2.548596e-5
GO:0034436 glycoprotein transport 2.548596e-5
GO:0031333 negative regulation of protein complex assembly 2.636210e-5
GO:0009199 ribonucleoside triphosphate metabolic process 2.639797e-5
GO:0043206 fibril organization 2.747916e-5
GO:0043587 tongue morphogenesis 2.821062e-5
GO:0006434 seryl-tRNA aminoacylation 2.917567e-5
GO:0050818 regulation of coagulation 2.954754e-5
GO:0034613 cellular protein localization 2.987281e-5
GO:0048562 embryonic organ morphogenesis 3.047563e-5
GO:0032206 positive regulation of telomere maintenance 3.080126e-5
GO:0019884 antigen processing and presentation of exogenous antigen 3.170363e-5
GO:0060956 endocardial cell differentiation 3.191138e-5
GO:0045061 thymic T cell selection 3.204940e-5
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 3.211161e-5
GO:0034340 response to type I interferon 3.259187e-5
GO:0009150 purine ribonucleotide metabolic process 3.332703e-5
GO:0051895 negative regulation of focal adhesion assembly 3.336399e-5
GO:0002906 negative regulation of mature B cell apoptosis 3.388155e-5
GO:0031647 regulation of protein stability 3.417303e-5
GO:0006886 intracellular protein transport 3.511948e-5
GO:0009141 nucleoside triphosphate metabolic process 3.708616e-5
GO:0050680 negative regulation of epithelial cell proliferation 3.745618e-5
GO:0001798 positive regulation of type IIa hypersensitivity 3.763506e-5
GO:0035264 multicellular organism growth 3.767037e-5
GO:0051295 establishment of meiotic spindle localization 3.789281e-5
GO:0072081 specification of nephron tubule identity 3.873390e-5
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 3.884140e-5
GO:0043585 nose morphogenesis 3.895256e-5
GO:0007440 foregut morphogenesis 4.444854e-5
GO:0032707 negative regulation of interleukin-23 production 4.561685e-5
GO:0046632 alpha-beta T cell differentiation 4.781555e-5
GO:0048259 regulation of receptor-mediated endocytosis 4.819440e-5
GO:0009259 ribonucleotide metabolic process 4.832910e-5
GO:0002376 immune system process 4.857273e-5
GO:0007632 visual behavior 4.981084e-5
GO:0007321 sperm displacement 5.115382e-5
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity 5.282613e-5
GO:0015698 inorganic anion transport 5.473595e-5
GO:0010757 negative regulation of plasminogen activation 5.499756e-5
GO:0007423 sensory organ development 5.544563e-5
GO:0001768 establishment of T cell polarity 5.652989e-5
GO:0050819 negative regulation of coagulation 5.684404e-5
GO:0001692 histamine metabolic process 5.847895e-5
GO:0070585 protein localization in mitochondrion 6.073308e-5
GO:0017187 peptidyl-glutamic acid carboxylation 6.129012e-5
GO:0097118 neuroligin clustering 6.236890e-5
GO:0001970 positive regulation of activation of membrane attack complex 6.236890e-5
GO:0031639 plasminogen activation 6.326237e-5
GO:0010872 regulation of cholesterol esterification 6.516922e-5
GO:0030194 positive regulation of blood coagulation 6.598991e-5
GO:0090231 regulation of spindle checkpoint 6.648404e-5
GO:0072659 protein localization in plasma membrane 6.673101e-5
GO:0009145 purine nucleoside triphosphate biosynthetic process 6.840379e-5
GO:0010984 regulation of lipoprotein particle clearance 6.870198e-5
GO:0051291 protein heterooligomerization 7.014501e-5
GO:0043535 regulation of blood vessel endothelial cell migration 7.102654e-5
GO:0006547 histidine metabolic process 7.185183e-5
GO:0060311 negative regulation of elastin catabolic process 7.218906e-5
GO:0060313 negative regulation of blood vessel remodeling 7.218906e-5
GO:0010711 negative regulation of collagen catabolic process 7.218906e-5
GO:0010703 negative regulation of histolysis 7.218906e-5
GO:0043537 negative regulation of blood vessel endothelial cell migration 7.339625e-5
GO:0010755 regulation of plasminogen activation 7.558398e-5
GO:0010758 regulation of macrophage chemotaxis 7.643111e-5
GO:0030198 extracellular matrix organization 7.670278e-5
GO:0090136 epithelial cell-cell adhesion 7.876015e-5
GO:0007509 mesoderm migration involved in gastrulation 8.144397e-5
GO:0070228 regulation of lymphocyte apoptosis 8.237191e-5
GO:0046034 ATP metabolic process 8.459288e-5
GO:0010812 negative regulation of cell-substrate adhesion 8.673684e-5
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 8.699551e-5
GO:0071622 regulation of granulocyte chemotaxis 8.734361e-5
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 8.783343e-5
GO:0010759 positive regulation of macrophage chemotaxis 8.786490e-5
GO:0032908 regulation of transforming growth factor beta1 production 8.800523e-5
GO:0072657 protein localization in membrane 8.910968e-5
GO:0050866 negative regulation of cell activation 9.048809e-5
GO:0042421 norepinephrine biosynthetic process 9.181280e-5
GO:0006706 steroid catabolic process 9.216354e-5
GO:0060088 auditory receptor cell stereocilium organization 9.297154e-5
GO:0070613 regulation of protein processing 9.826573e-5
GO:0034465 response to carbon monoxide 9.975502e-5
GO:0008625 induction of apoptosis via death domain receptors 1.005194e-4
GO:0045198 establishment of epithelial cell apical/basal polarity 1.014288e-4
GO:0006939 smooth muscle contraction 1.036975e-4
GO:0003084 positive regulation of systemic arterial blood pressure 1.040916e-4
GO:0030217 T cell differentiation 1.068646e-4
GO:0001867 complement activation, lectin pathway 1.071990e-4
GO:0085029 extracellular matrix assembly 1.085195e-4
GO:0048168 regulation of neuronal synaptic plasticity 1.089896e-4
GO:0031960 response to corticosteroid stimulus 1.107469e-4
GO:0072143 mesangial cell development 1.126271e-4
GO:0045777 positive regulation of blood pressure 1.146110e-4
GO:0030834 regulation of actin filament depolymerization 1.150645e-4
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 1.162597e-4
GO:0000185 activation of MAPKKK activity 1.179282e-4
GO:2000377 regulation of reactive oxygen species metabolic process 1.181932e-4
GO:0003206 cardiac chamber morphogenesis 1.185084e-4
GO:0050779 RNA destabilization 1.192131e-4
GO:0048771 tissue remodeling 1.194804e-4
GO:0010594 regulation of endothelial cell migration 1.242872e-4
GO:0006766 vitamin metabolic process 1.254183e-4
GO:0045112 integrin biosynthetic process 1.255559e-4
GO:0007051 spindle organization 1.262662e-4
GO:0051937 catecholamine transport 1.313124e-4
GO:0030029 actin filament-based process 1.326035e-4
GO:0060119 inner ear receptor cell development 1.338950e-4
GO:0002115 store-operated calcium entry 1.362524e-4
GO:0006801 superoxide metabolic process 1.382352e-4
GO:0008633 activation of pro-apoptotic gene products 1.416077e-4
GO:0045416 positive regulation of interleukin-8 biosynthetic process 1.418649e-4
GO:0009142 nucleoside triphosphate biosynthetic process 1.422202e-4
GO:0009303 rRNA transcription 1.464443e-4
GO:0006904 vesicle docking involved in exocytosis 1.471544e-4
GO:0042098 T cell proliferation 1.479205e-4
GO:0071356 cellular response to tumor necrosis factor 1.497189e-4
GO:0048261 negative regulation of receptor-mediated endocytosis 1.517587e-4
GO:0009207 purine ribonucleoside triphosphate catabolic process 1.562174e-4
GO:0021984 adenohypophysis development 1.624168e-4
GO:0009146 purine nucleoside triphosphate catabolic process 1.629733e-4
GO:0048659 smooth muscle cell proliferation 1.646353e-4
GO:0007506 gonadal mesoderm development 1.646353e-4
GO:0048251 elastic fiber assembly 1.680560e-4
GO:0042743 hydrogen peroxide metabolic process 1.685156e-4
GO:0019532 oxalate transport 1.733252e-4
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.769197e-4
GO:0050710 negative regulation of cytokine secretion 1.769272e-4
GO:0061143 alveolar primary septum development 1.810942e-4
GO:0035845 photoreceptor cell outer segment organization 1.811525e-4
GO:0050951 sensory perception of temperature stimulus 1.836405e-4
GO:0010466 negative regulation of peptidase activity 1.848748e-4
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 1.869945e-4
GO:0007132 meiotic metaphase I 1.895347e-4
GO:0009201 ribonucleoside triphosphate biosynthetic process 1.897663e-4
GO:0072655 establishment of protein localization in mitochondrion 1.900032e-4
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 1.916300e-4
GO:0061157 mRNA destabilization 1.916300e-4
GO:0008628 induction of apoptosis by hormones 1.973944e-4
GO:0003161 cardiac conduction system development 1.976427e-4
GO:0006626 protein targeting to mitochondrion 2.023646e-4
GO:0009143 nucleoside triphosphate catabolic process 2.068446e-4
GO:0010810 regulation of cell-substrate adhesion 2.069340e-4
GO:0097116 gephyrin clustering 2.078747e-4
GO:0016337 cell-cell adhesion 2.210613e-4
GO:0002690 positive regulation of leukocyte chemotaxis 2.214109e-4
GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development 2.243123e-4
GO:0060356 leucine import 2.263700e-4
GO:0002883 regulation of hypersensitivity 2.268779e-4
GO:0031640 killing of cells of other organism 2.288781e-4
GO:0060070 canonical Wnt receptor signaling pathway 2.312047e-4
GO:0010763 positive regulation of fibroblast migration 2.345698e-4
GO:0044062 regulation of excretion 2.347492e-4
GO:0048241 epinephrine transport 2.380757e-4
GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 2.425761e-4
GO:0009119 ribonucleoside metabolic process 2.461642e-4
GO:0006754 ATP biosynthetic process 2.540382e-4
GO:0048752 semicircular canal morphogenesis 2.560573e-4
GO:0015696 ammonium transport 2.578002e-4
GO:0007253 cytoplasmic sequestering of NF-kappaB 2.578002e-4
GO:0032462 regulation of protein homooligomerization 2.588139e-4
GO:0007268 synaptic transmission 2.589519e-4
GO:0009154 purine ribonucleotide catabolic process 2.611503e-4
GO:0042797 tRNA transcription from RNA polymerase III promoter 2.614160e-4
GO:0060973 cell migration involved in heart development 2.614160e-4
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 2.614160e-4
GO:0060117 auditory receptor cell development 2.676119e-4
GO:0003231 cardiac ventricle development 2.698435e-4
GO:0032925 regulation of activin receptor signaling pathway 2.702425e-4
GO:0010934 macrophage cytokine production 2.773325e-4
GO:0045040 protein import into mitochondrial outer membrane 2.788949e-4
GO:0019370 leukotriene biosynthetic process 2.793352e-4
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 2.801454e-4
GO:0009261 ribonucleotide catabolic process 2.885323e-4
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 2.900999e-4
GO:0034369 plasma lipoprotein particle remodeling 2.957156e-4
GO:0045806 negative regulation of endocytosis 2.968153e-4
GO:0002579 positive regulation of antigen processing and presentation 2.968942e-4
GO:0021636 trigeminal nerve morphogenesis 2.990891e-4
GO:0003308 negative regulation of Wnt receptor signaling pathway involved in heart development 3.042886e-4
GO:0065008 regulation of biological quality 3.067473e-4
GO:0018200 peptidyl-glutamic acid modification 3.080538e-4
GO:0097104 postsynaptic membrane assembly 3.150104e-4
GO:0097119 postsynaptic density protein 95 clustering 3.150104e-4
GO:0006691 leukotriene metabolic process 3.172592e-4
GO:0003205 cardiac chamber development 3.218524e-4
GO:0006693 prostaglandin metabolic process 3.232397e-4
GO:0051128 regulation of cellular component organization 3.237909e-4
GO:0001878 response to yeast 3.369943e-4
GO:0042542 response to hydrogen peroxide 3.384211e-4
GO:0042221 response to chemical stimulus 3.409344e-4
GO:0033077 T cell differentiation in thymus 3.414644e-4
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 3.444221e-4
GO:0046333 octopamine metabolic process 3.513488e-4
GO:0042309 homoiothermy 3.513488e-4
GO:0034612 response to tumor necrosis factor 3.530896e-4
GO:0032926 negative regulation of activin receptor signaling pathway 3.532821e-4
GO:0021773 striatal medium spiny neuron differentiation 3.568160e-4
GO:0043586 tongue development 3.599001e-4
GO:0019228 regulation of action potential in neuron 3.619612e-4
GO:0043583 ear development 3.642560e-4
GO:0070213 protein auto-ADP-ribosylation 3.672686e-4
GO:0006911 phagocytosis, engulfment 3.801196e-4
GO:0015669 gas transport 3.815442e-4
GO:0006936 muscle contraction 4.019634e-4
GO:0048708 astrocyte differentiation 4.020408e-4
GO:0048711 positive regulation of astrocyte differentiation 4.090180e-4
GO:0034614 cellular response to reactive oxygen species 4.101497e-4
GO:0043534 blood vessel endothelial cell migration 4.121401e-4
GO:0008542 visual learning 4.121401e-4
GO:0032212 positive regulation of telomere maintenance via telomerase 4.155106e-4
GO:0032497 detection of lipopolysaccharide 4.194813e-4
GO:0050921 positive regulation of chemotaxis 4.330416e-4
GO:0060446 branching involved in open tracheal system development 4.363873e-4
GO:0048613 embryonic ectodermal digestive tract morphogenesis 4.363873e-4
GO:0060461 right lung morphogenesis 4.363873e-4
GO:0090131 mesenchyme migration 4.363873e-4
GO:0048371 lateral mesodermal cell differentiation 4.363873e-4
GO:0010107 potassium ion import 4.363873e-4
GO:0014822 detection of wounding 4.363873e-4
GO:0009416 response to light stimulus 4.455169e-4
GO:0002077 acrosome matrix dispersal 4.465073e-4
GO:0021523 somatic motor neuron differentiation 4.481468e-4
GO:0046128 purine ribonucleoside metabolic process 4.552221e-4
GO:0035082 axoneme assembly 4.627239e-4
GO:0072208 metanephric smooth muscle tissue development 4.782883e-4
GO:0072184 renal vesicle progenitor cell differentiation 4.782883e-4
GO:0072259 metanephric interstitial cell development 4.782883e-4
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 4.782883e-4
GO:0072169 specification of posterior mesonephric tubule identity 4.782883e-4
GO:0008065 establishment of blood-nerve barrier 4.782883e-4
GO:0072168 specification of anterior mesonephric tubule identity 4.782883e-4
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 4.794245e-4
GO:0010596 negative regulation of endothelial cell migration 4.808742e-4
GO:0045019 negative regulation of nitric oxide biosynthetic process 4.914128e-4
GO:0034063 stress granule assembly 4.991437e-4
GO:0015671 oxygen transport 4.991437e-4
GO:0014873 response to muscle activity involved in regulation of muscle adaptation 4.996905e-4
GO:0061049 cell growth involved in cardiac muscle cell development 4.996905e-4
GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure 4.996905e-4
GO:0003331 positive regulation of extracellular matrix constituent secretion 4.996905e-4
GO:0008637 apoptotic mitochondrial changes 5.114397e-4
GO:0048368 lateral mesoderm development 5.126177e-4
GO:0032891 negative regulation of organic acid transport 5.195069e-4
GO:0051893 regulation of focal adhesion assembly 5.214285e-4
GO:0015884 folic acid transport 5.269902e-4
GO:0010595 positive regulation of endothelial cell migration 5.283774e-4
GO:0007010 cytoskeleton organization 5.289675e-4
GO:0030177 positive regulation of Wnt receptor signaling pathway 5.320344e-4
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 5.371192e-4
GO:0070327 thyroid hormone transport 5.405263e-4
GO:0001779 natural killer cell differentiation 5.458511e-4
GO:0050829 defense response to Gram-negative bacterium 5.477077e-4
GO:0044240 multicellular organismal lipid catabolic process 5.511714e-4
GO:0032571 response to vitamin K 5.543433e-4
GO:0071593 lymphocyte aggregation 5.547449e-4
GO:0035457 cellular response to interferon-alpha 5.652045e-4
GO:0008366 axon ensheathment 5.698034e-4
GO:0048210 Golgi vesicle fusion to target membrane 5.815933e-4
GO:0045355 negative regulation of interferon-alpha biosynthetic process 5.815933e-4
GO:0001516 prostaglandin biosynthetic process 5.818348e-4
GO:0070212 protein poly-ADP-ribosylation 5.972727e-4
GO:0050877 neurological system process 6.025205e-4
GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation 6.049131e-4
GO:0072337 modified amino acid transport 6.129722e-4
GO:0009152 purine ribonucleotide biosynthetic process 6.131935e-4
GO:0051181 cofactor transport 6.157349e-4
GO:0045608 negative regulation of auditory receptor cell differentiation 6.191952e-4
GO:0090232 positive regulation of spindle checkpoint 6.308825e-4
GO:0003307 regulation of Wnt receptor signaling pathway involved in heart development 6.378597e-4
GO:0003179 heart valve morphogenesis 6.394867e-4
GO:0006725 cellular aromatic compound metabolic process 6.406534e-4
GO:0071529 cementum mineralization 6.532774e-4
GO:0006816 calcium ion transport 6.539807e-4
GO:0030048 actin filament-based movement 6.683629e-4
GO:0008285 negative regulation of cell proliferation 6.690498e-4
GO:0008360 regulation of cell shape 6.756682e-4
GO:0019049 evasion of host defenses by virus 6.861604e-4
GO:0051496 positive regulation of stress fiber assembly 6.887498e-4
GO:0010888 negative regulation of lipid storage 6.909821e-4
GO:0071675 regulation of mononuclear cell migration 6.961793e-4
GO:0010985 negative regulation of lipoprotein particle clearance 6.983648e-4
GO:0006200 ATP catabolic process 7.107512e-4
GO:0006884 cell volume homeostasis 7.271238e-4
GO:0014002 astrocyte development 7.278896e-4
GO:0050920 regulation of chemotaxis 7.293175e-4
GO:0001933 negative regulation of protein phosphorylation 7.385642e-4
GO:0048872 homeostasis of number of cells 7.463473e-4
GO:0003334 keratinocyte development 7.485889e-4
GO:0006695 cholesterol biosynthetic process 7.568365e-4
GO:0050896 response to stimulus 7.594221e-4
GO:0045930 negative regulation of mitotic cell cycle 7.628144e-4
GO:0051896 regulation of protein kinase B signaling cascade 7.753080e-4
GO:0060251 regulation of glial cell proliferation 7.763651e-4
GO:0042116 macrophage activation 7.769187e-4
GO:0050965 detection of temperature stimulus involved in sensory perception of pain 7.990308e-4
GO:0032383 regulation of intracellular cholesterol transport 7.990308e-4
GO:0006836 neurotransmitter transport 8.030851e-4
GO:0060426 lung vasculature development 8.034414e-4
GO:0035813 regulation of renal sodium excretion 8.127483e-4
GO:0043313 regulation of neutrophil degranulation 8.190317e-4
GO:0048857 neural nucleus development 8.194800e-4
GO:0045217 cell-cell junction maintenance 8.197242e-4
GO:0030299 intestinal cholesterol absorption 8.495546e-4
GO:0042558 pteridine-containing compound metabolic process 8.521822e-4
GO:0043900 regulation of multi-organism process 8.568749e-4
GO:0003157 endocardium development 8.822788e-4
GO:0071482 cellular response to light stimulus 8.847941e-4
GO:0007512 adult heart development 9.054029e-4
GO:0045620 negative regulation of lymphocyte differentiation 9.074549e-4
GO:0055099 response to high density lipoprotein particle stimulus 9.461526e-4
GO:0010543 regulation of platelet activation 9.648830e-4
GO:0048545 response to steroid hormone stimulus 9.682112e-4
GO:0032459 regulation of protein oligomerization 9.759398e-4
GO:0030432 peristalsis 9.787932e-4
GO:2000667 positive regulation of interleukin-13 secretion 1.030955e-3
GO:2000703 negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation 1.030955e-3
GO:2000734 negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation 1.030955e-3
GO:2000665 regulation of interleukin-13 secretion 1.030955e-3
GO:0040040 thermosensory behavior 1.030955e-3
GO:2000664 positive regulation of interleukin-5 secretion 1.030955e-3
GO:2000607 negative regulation of cell proliferation involved in mesonephros development 1.030955e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0045940 positive regulation of steroid metabolic process 1.288429e-15
GO:0019218 regulation of steroid metabolic process 1.540320e-15
GO:0033700 phospholipid efflux 8.335341e-13
GO:0034369 plasma lipoprotein particle remodeling 1.107385e-11
GO:0060192 negative regulation of lipase activity 2.150423e-11
GO:0030301 cholesterol transport 3.786042e-11
GO:0046890 regulation of lipid biosynthetic process 4.264106e-11
GO:0034382 chylomicron remnant clearance 1.291169e-10
GO:0010872 regulation of cholesterol esterification 1.564439e-10
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.642276e-10
GO:0033344 cholesterol efflux 6.939116e-10
GO:0010873 positive regulation of cholesterol esterification 7.215566e-10
GO:0042304 regulation of fatty acid biosynthetic process 8.042770e-10
GO:0010984 regulation of lipoprotein particle clearance 1.559570e-9
GO:0051005 negative regulation of lipoprotein lipase activity 1.653868e-9
GO:0032374 regulation of cholesterol transport 1.800046e-9
GO:0010985 negative regulation of lipoprotein particle clearance 1.994234e-9
GO:0032352 positive regulation of hormone metabolic process 3.990110e-9
GO:0010900 negative regulation of phosphatidylcholine catabolic process 4.296273e-9
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 4.383551e-9
GO:0050810 regulation of steroid biosynthetic process 1.049043e-8
GO:0045717 negative regulation of fatty acid biosynthetic process 1.321098e-8
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 1.657300e-8
GO:0071827 plasma lipoprotein particle organization 3.790273e-8
GO:0048739 cardiac muscle fiber development 5.595884e-8
GO:0016074 snoRNA metabolic process 5.890449e-8
GO:0032350 regulation of hormone metabolic process 6.763974e-8
GO:0010893 positive regulation of steroid biosynthetic process 7.482825e-8
GO:0032375 negative regulation of cholesterol transport 9.407317e-8
GO:0006641 triglyceride metabolic process 1.002624e-7
GO:0033490 cholesterol biosynthetic process via lathosterol 1.630442e-7
GO:0046885 regulation of hormone biosynthetic process 2.308109e-7
GO:0060191 regulation of lipase activity 2.667164e-7
GO:0090031 positive regulation of steroid hormone biosynthetic process 2.848020e-7
GO:0002227 innate immune response in mucosa 3.317290e-7
GO:0051004 regulation of lipoprotein lipase activity 3.867892e-7
GO:0046464 acylglycerol catabolic process 3.935455e-7
GO:0090030 regulation of steroid hormone biosynthetic process 3.938864e-7
GO:0019433 triglyceride catabolic process 3.986751e-7
GO:0046886 positive regulation of hormone biosynthetic process 4.473443e-7
GO:0060696 regulation of phospholipid catabolic process 4.838520e-7
GO:0002642 positive regulation of immunoglobulin biosynthetic process 5.084655e-7
GO:0002456 T cell mediated immunity 6.270316e-7
GO:0034447 very-low-density lipoprotein particle clearance 6.816690e-7
GO:0046889 positive regulation of lipid biosynthetic process 1.118041e-6
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 1.245582e-6
GO:0050995 negative regulation of lipid catabolic process 1.497797e-6
GO:0050927 positive regulation of positive chemotaxis 1.606276e-6
GO:0006982 response to lipid hydroperoxide 1.692026e-6
GO:0046503 glycerolipid catabolic process 1.780222e-6
GO:0070328 triglyceride homeostasis 1.917737e-6
GO:0030300 regulation of intestinal cholesterol absorption 2.060157e-6
GO:0048261 negative regulation of receptor-mediated endocytosis 2.066787e-6
GO:0043503 skeletal muscle fiber adaptation 2.361643e-6
GO:0008203 cholesterol metabolic process 2.463319e-6
GO:0002449 lymphocyte mediated immunity 2.602813e-6
GO:0019216 regulation of lipid metabolic process 2.644318e-6
GO:0060037 pharyngeal system development 2.840516e-6
GO:0055090 acylglycerol homeostasis 3.005374e-6
GO:0090181 regulation of cholesterol metabolic process 3.180198e-6
GO:0045922 negative regulation of fatty acid metabolic process 3.321554e-6
GO:0045834 positive regulation of lipid metabolic process 3.553457e-6
GO:0050921 positive regulation of chemotaxis 3.641427e-6
GO:0006639 acylglycerol metabolic process 3.970595e-6
GO:0033238 regulation of cellular amine metabolic process 4.842982e-6
GO:0050930 induction of positive chemotaxis 5.386434e-6
GO:0006638 neutral lipid metabolic process 6.380989e-6
GO:0050926 regulation of positive chemotaxis 6.900758e-6
GO:0044058 regulation of digestive system process 7.072659e-6
GO:0030241 skeletal muscle myosin thick filament assembly 7.073418e-6
GO:0006869 lipid transport 8.026591e-6
GO:0008207 C21-steroid hormone metabolic process 8.910233e-6
GO:0010876 lipid localization 1.052097e-5
GO:0048520 positive regulation of behavior 1.217779e-5
GO:0051129 negative regulation of cellular component organization 1.434747e-5
GO:0043691 reverse cholesterol transport 1.525745e-5
GO:0060415 muscle tissue morphogenesis 1.622071e-5
GO:0033239 negative regulation of cellular amine metabolic process 1.626971e-5
GO:0072376 protein activation cascade 1.637822e-5
GO:0016079 synaptic vesicle exocytosis 1.642391e-5
GO:0016125 sterol metabolic process 1.925989e-5
GO:0060290 transdifferentiation 2.057703e-5
GO:0002443 leukocyte mediated immunity 2.242044e-5
GO:0002921 negative regulation of humoral immune response 2.282112e-5
GO:0000305 response to oxygen radical 2.439285e-5
GO:0045065 cytotoxic T cell differentiation 2.454185e-5
GO:0006956 complement activation 2.624819e-5
GO:0048747 muscle fiber development 2.691908e-5
GO:0045540 regulation of cholesterol biosynthetic process 2.786667e-5
GO:0032369 negative regulation of lipid transport 3.109990e-5
GO:0007218 neuropeptide signaling pathway 3.206214e-5
GO:0050994 regulation of lipid catabolic process 3.208114e-5
GO:0003012 muscle system process 3.680187e-5
GO:0060620 regulation of cholesterol import 3.696092e-5
GO:0032693 negative regulation of interleukin-10 production 4.069308e-5
GO:0010896 regulation of triglyceride catabolic process 4.253069e-5
GO:0001867 complement activation, lectin pathway 4.337247e-5
GO:0045577 regulation of B cell differentiation 4.930709e-5
GO:0002358 B cell homeostatic proliferation 5.035404e-5
GO:0001845 phagolysosome assembly 5.035404e-5
GO:0055010 ventricular cardiac muscle tissue morphogenesis 5.085895e-5
GO:0006936 muscle contraction 5.182466e-5
GO:0010625 positive regulation of Schwann cell proliferation 5.429870e-5
GO:0060621 negative regulation of cholesterol import 5.554487e-5
GO:0000303 response to superoxide 5.557016e-5
GO:0019240 citrulline biosynthetic process 5.870005e-5
GO:0044342 type B pancreatic cell proliferation 5.936938e-5
GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine 5.936938e-5
GO:0002635 negative regulation of germinal center formation 5.936938e-5
GO:0031034 myosin filament assembly 5.979638e-5
GO:0051615 histamine uptake 6.047047e-5
GO:0006642 triglyceride mobilization 6.369591e-5
GO:0097006 regulation of plasma lipoprotein particle levels 6.414908e-5
GO:0060537 muscle tissue development 7.311725e-5
GO:0002830 positive regulation of type 2 immune response 7.545503e-5
GO:0035640 exploration behavior 8.374319e-5
GO:0006662 glycerol ether metabolic process 8.674701e-5
GO:0003229 ventricular cardiac muscle tissue development 9.108193e-5
GO:0042492 gamma-delta T cell differentiation 9.487274e-5
GO:0003208 cardiac ventricle morphogenesis 9.527296e-5
GO:0044062 regulation of excretion 9.603164e-5
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1.065995e-4
GO:0042632 cholesterol homeostasis 1.077384e-4
GO:0051494 negative regulation of cytoskeleton organization 1.087162e-4
GO:0007016 cytoskeletal anchoring at plasma membrane 1.089685e-4
GO:0006700 C21-steroid hormone biosynthetic process 1.090232e-4
GO:0050819 negative regulation of coagulation 1.171417e-4
GO:0032368 regulation of lipid transport 1.187404e-4
GO:0090102 cochlea development 1.191375e-4
GO:0010454 negative regulation of cell fate commitment 1.231141e-4
GO:0009582 detection of abiotic stimulus 1.233714e-4
GO:0017004 cytochrome complex assembly 1.260128e-4
GO:0007517 muscle organ development 1.261116e-4
GO:0032094 response to food 1.345103e-4
GO:0060754 positive regulation of mast cell chemotaxis 1.348549e-4
GO:0046600 negative regulation of centriole replication 1.355099e-4
GO:0007269 neurotransmitter secretion 1.411391e-4
GO:0002707 negative regulation of lymphocyte mediated immunity 1.468427e-4
GO:0050760 negative regulation of thymidylate synthase biosynthetic process 1.531335e-4
GO:0018364 peptidyl-glutamine methylation 1.531335e-4
GO:0008633 activation of pro-apoptotic gene products 1.542384e-4
GO:0071169 establishment of protein localization to chromatin 1.562717e-4
GO:0034370 triglyceride-rich lipoprotein particle remodeling 1.565050e-4
GO:0005997 xylulose metabolic process 1.602607e-4
GO:0019430 removal of superoxide radicals 1.721713e-4
GO:0001844 protein insertion into mitochondrial membrane involved in induction of apoptosis 1.787774e-4
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.813187e-4
GO:0034381 plasma lipoprotein particle clearance 1.895260e-4
GO:0032231 regulation of actin filament bundle assembly 2.033986e-4
GO:0042732 D-xylose metabolic process 2.110323e-4
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.125011e-4
GO:0000387 spliceosomal snRNP assembly 2.238300e-4
GO:0060193 positive regulation of lipase activity 2.269853e-4
GO:0050746 regulation of lipoprotein metabolic process 2.326522e-4
GO:0032103 positive regulation of response to external stimulus 2.515230e-4
GO:0010982 regulation of high-density lipoprotein particle clearance 2.537528e-4
GO:0045906 negative regulation of vasoconstriction 2.695829e-4
GO:0045806 negative regulation of endocytosis 2.728934e-4
GO:0061061 muscle structure development 2.745088e-4
GO:0003205 cardiac chamber development 2.762933e-4
GO:0055009 atrial cardiac muscle tissue morphogenesis 2.763890e-4
GO:0003231 cardiac ventricle development 2.800590e-4
GO:0014706 striated muscle tissue development 2.813899e-4
GO:0031100 organ regeneration 2.855593e-4
GO:0033979 box H/ACA snoRNA metabolic process 2.999249e-4
GO:0046086 adenosine biosynthetic process 2.999249e-4
GO:0010918 positive regulation of mitochondrial membrane potential 2.999249e-4
GO:0006196 AMP catabolic process 2.999249e-4
GO:0002690 positive regulation of leukocyte chemotaxis 3.022061e-4
GO:0007522 visceral muscle development 3.056240e-4
GO:0061041 regulation of wound healing 3.179545e-4
GO:0030878 thyroid gland development 3.234349e-4
GO:0030029 actin filament-based process 3.239792e-4
GO:0045823 positive regulation of heart contraction 3.448744e-4
GO:0034374 low-density lipoprotein particle remodeling 3.610703e-4
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 3.821671e-4
GO:0035691 macrophage migration inhibitory factor signaling pathway 3.821671e-4
GO:0018904 organic ether metabolic process 3.994927e-4
GO:0007010 cytoskeleton organization 4.073149e-4
GO:0008211 glucocorticoid metabolic process 4.134689e-4
GO:0034551 mitochondrial respiratory chain complex III assembly 4.247503e-4
GO:0002897 positive regulation of central B cell tolerance induction 4.247503e-4
GO:0002508 central tolerance induction 4.247503e-4
GO:0000238 zygotene 4.247503e-4
GO:0090183 regulation of kidney development 4.349980e-4
GO:0019884 antigen processing and presentation of exogenous antigen 4.417671e-4
GO:0034372 very-low-density lipoprotein particle remodeling 4.428985e-4
GO:0002902 regulation of B cell apoptosis 4.438161e-4
GO:0007183 SMAD protein complex assembly 4.459320e-4
GO:0006887 exocytosis 4.509764e-4
GO:0043279 response to alkaloid 4.576840e-4
GO:0007202 activation of phospholipase C activity 4.708384e-4
GO:0045343 regulation of MHC class I biosynthetic process 4.719019e-4
GO:0065008 regulation of biological quality 4.761751e-4
GO:0042454 ribonucleoside catabolic process 4.835093e-4
GO:0045579 positive regulation of B cell differentiation 4.848018e-4
GO:0002250 adaptive immune response 4.864232e-4
GO:0008202 steroid metabolic process 5.104239e-4
GO:0061290 canonical Wnt receptor signaling pathway involved in metanephric kidney development 5.235191e-4
GO:0046599 regulation of centriole replication 5.235191e-4
GO:0030195 negative regulation of blood coagulation 5.387468e-4
GO:0045217 cell-cell junction maintenance 5.390648e-4
GO:0043583 ear development 5.432377e-4
GO:0042730 fibrinolysis 5.464910e-4
GO:0046604 positive regulation of mitotic centrosome separation 5.465623e-4
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 5.530068e-4
GO:0048644 muscle organ morphogenesis 5.638317e-4
GO:0048878 chemical homeostasis 5.678282e-4
GO:0055008 cardiac muscle tissue morphogenesis 5.802887e-4
GO:0009133 nucleoside diphosphate biosynthetic process 5.972229e-4
GO:0002478 antigen processing and presentation of exogenous peptide antigen 6.099404e-4
GO:0051346 negative regulation of hydrolase activity 6.174792e-4
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 6.438527e-4
GO:2000611 positive regulation of thyroid hormone generation 6.501459e-4
GO:0006066 alcohol metabolic process 6.558890e-4
GO:0046434 organophosphate catabolic process 6.596036e-4
GO:0070869 heterochromatin formation involved in chromatin silencing 6.631349e-4
GO:0070327 thyroid hormone transport 6.705445e-4
GO:0030049 muscle filament sliding 6.925847e-4
GO:0030035 microspike assembly 6.988235e-4
GO:0001935 endothelial cell proliferation 7.102562e-4
GO:0046874 quinolinate metabolic process 7.377651e-4
GO:0002088 lens development in camera-type eye 7.438040e-4
GO:0071956 cellular component maintenance at cellular level 7.478199e-4
GO:0003350 pulmonary myocardium development 7.607359e-4
GO:0051204 protein insertion into mitochondrial membrane 7.776997e-4
GO:0060070 canonical Wnt receptor signaling pathway 7.779741e-4
GO:0072513 positive regulation of secondary heart field cardioblast proliferation 8.016397e-4
GO:0060026 convergent extension 8.034978e-4
GO:0009887 organ morphogenesis 8.184559e-4
GO:0006958 complement activation, classical pathway 8.205664e-4
GO:0045647 negative regulation of erythrocyte differentiation 8.409688e-4
GO:0033085 negative regulation of T cell differentiation in thymus 8.409688e-4
GO:0003206 cardiac chamber morphogenesis 8.457571e-4
GO:0009115 xanthine catabolic process 8.513485e-4
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 8.521191e-4
GO:0015671 oxygen transport 8.521191e-4
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 8.521191e-4
GO:0045345 positive regulation of MHC class I biosynthetic process 8.923209e-4
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 9.374145e-4
GO:0060299 negative regulation of sarcomere organization 9.374145e-4
GO:0006258 UDP-glucose catabolic process 9.374145e-4
GO:0010455 positive regulation of cell fate commitment 9.374145e-4
GO:0034442 regulation of lipoprotein oxidation 9.439339e-4
GO:0045608 negative regulation of auditory receptor cell differentiation 9.603089e-4
GO:0010897 negative regulation of triglyceride catabolic process 9.603089e-4
GO:0010987 negative regulation of high-density lipoprotein particle clearance 9.603089e-4
GO:0045576 mast cell activation 9.638155e-4
GO:0032101 regulation of response to external stimulus 9.727403e-4
GO:0070627 ferrous iron import 1.007200e-3
GO:0090177 establishment of planar polarity involved in neural tube closure 1.007200e-3
GO:0008057 eye pigment granule organization 1.007200e-3
GO:0046853 inositol or phosphatidylinositol phosphorylation 1.007200e-3
GO:0015692 lead ion transport 1.007200e-3
GO:0015676 vanadium ion transport 1.007200e-3
GO:0032233 positive regulation of actin filament bundle assembly 1.025023e-3
GO:0009581 detection of external stimulus 1.031980e-3
GO:0070306 lens fiber cell differentiation 1.036066e-3
GO:0002889 regulation of immunoglobulin mediated immune response 1.055596e-3
GO:0060020 Bergmann glial cell differentiation 1.058161e-3
GO:0045723 positive regulation of fatty acid biosynthetic process 1.059278e-3
GO:0035304 regulation of protein dephosphorylation 1.093259e-3
GO:0002086 diaphragm contraction 1.103792e-3
GO:0045226 extracellular polysaccharide biosynthetic process 1.103792e-3
GO:0019359 nicotinamide nucleotide biosynthetic process 1.126249e-3
GO:0009996 negative regulation of cell fate specification 1.126249e-3
GO:0042267 natural killer cell mediated cytotoxicity 1.129952e-3
GO:0048731 system development 1.136536e-3
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 1.151317e-3
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 1.155529e-3
GO:0022417 protein maturation by protein folding 1.155529e-3
GO:0051239 regulation of multicellular organismal process 1.188391e-3
GO:0002740 negative regulation of cytokine secretion involved in immune response 1.199695e-3
GO:0006959 humoral immune response 1.210036e-3
GO:0050748 negative regulation of lipoprotein metabolic process 1.215650e-3
GO:0007423 sensory organ development 1.217656e-3
GO:0033025 regulation of mast cell apoptosis 1.244822e-3
GO:0006917 induction of apoptosis 1.245005e-3
GO:0046110 xanthine metabolic process 1.247395e-3
GO:0032717 negative regulation of interleukin-8 production 1.247395e-3
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 1.249242e-3
GO:0006438 valyl-tRNA aminoacylation 1.249242e-3
GO:0010863 positive regulation of phospholipase C activity 1.262675e-3
GO:0043502 regulation of muscle adaptation 1.277657e-3
GO:0051492 regulation of stress fiber assembly 1.278170e-3
GO:0070670 response to interleukin-4 1.287026e-3
GO:0051905 establishment of pigment granule localization 1.303277e-3
GO:0060251 regulation of glial cell proliferation 1.307971e-3
GO:0048729 tissue morphogenesis 1.323426e-3
GO:0002820 negative regulation of adaptive immune response 1.325699e-3
GO:0060749 mammary gland alveolus development 1.347637e-3
GO:0071702 organic substance transport 1.379783e-3
GO:0012502 induction of programmed cell death 1.405109e-3
GO:0048563 post-embryonic organ morphogenesis 1.425945e-3
GO:0002385 mucosal immune response 1.425945e-3
GO:0008105 asymmetric protein localization 1.430786e-3
GO:0009164 nucleoside catabolic process 1.457437e-3
GO:0007621 negative regulation of female receptivity 1.496409e-3
GO:0045607 regulation of auditory receptor cell differentiation 1.496409e-3
GO:0000052 citrulline metabolic process 1.496409e-3
GO:0055088 lipid homeostasis 1.499252e-3
GO:0032736 positive regulation of interleukin-13 production 1.499526e-3
GO:0030263 apoptotic chromosome condensation 1.501800e-3
GO:0002352 B cell negative selection 1.501800e-3
GO:0009169 purine ribonucleoside monophosphate catabolic process 1.501800e-3
GO:0003016 respiratory system process 1.515882e-3
GO:0045930 negative regulation of mitotic cell cycle 1.535246e-3
GO:0051919 positive regulation of fibrinolysis 1.550858e-3
GO:0070366 regulation of hepatocyte differentiation 1.550858e-3
GO:0006705 mineralocorticoid biosynthetic process 1.552665e-3
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1.566993e-3
GO:0002739 regulation of cytokine secretion involved in immune response 1.572278e-3
GO:0032026 response to magnesium ion 1.575749e-3
GO:0051006 positive regulation of lipoprotein lipase activity 1.625024e-3
GO:0061009 common bile duct development 1.633689e-3
GO:0045542 positive regulation of cholesterol biosynthetic process 1.633689e-3
GO:0030036 actin cytoskeleton organization 1.634364e-3
GO:0042537 benzene-containing compound metabolic process 1.668293e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.685893e-3
GO:0008637 apoptotic mitochondrial changes 1.748000e-3
GO:0016998 cell wall macromolecule catabolic process 1.751062e-3
GO:0090086 negative regulation of protein deubiquitination 1.791948e-3
GO:0071674 mononuclear cell migration 1.791948e-3
GO:0003094 glomerular filtration 1.791948e-3
GO:0042946 glucoside transport 1.791948e-3
GO:0032571 response to vitamin K 1.799153e-3
GO:0034375 high-density lipoprotein particle remodeling 1.800520e-3
GO:0019852 L-ascorbic acid metabolic process 1.843301e-3
GO:0006584 catecholamine metabolic process 1.862864e-3
GO:0016576 histone dephosphorylation 1.869232e-3
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 1.908289e-3
GO:0048239 negative regulation of DNA recombination at telomere 1.911568e-3
GO:0042450 arginine biosynthetic process via ornithine 1.911568e-3
GO:0006430 lysyl-tRNA aminoacylation 1.911568e-3
GO:0019676 ammonia assimilation cycle 1.911568e-3
GO:0033617 mitochondrial respiratory chain complex IV assembly 1.911568e-3
GO:0048690 regulation of axon extension involved in regeneration 1.928595e-3
GO:0035552 oxidative single-stranded DNA demethylation 1.928595e-3
GO:0051297 centrosome organization 2.007888e-3
GO:0042220 response to cocaine 2.007888e-3
GO:0050982 detection of mechanical stimulus 2.019642e-3
GO:0048839 inner ear development 2.081364e-3
GO:0015734 taurine transport 2.116001e-3
GO:0002904 positive regulation of B cell apoptosis 2.126174e-3
GO:0006811 ion transport 2.128574e-3
GO:0050847 progesterone receptor signaling pathway 2.133728e-3
GO:0035235 ionotropic glutamate receptor signaling pathway 2.150502e-3
GO:0003007 heart morphogenesis 2.172291e-3
GO:0070383 DNA cytosine deamination 2.211896e-3
GO:0043985 histone H4-R3 methylation 2.211896e-3
GO:0010529 negative regulation of transposition 2.211896e-3
GO:0010977 negative regulation of neuron projection development 2.232189e-3
GO:0003062 regulation of heart rate by chemical signal 2.235533e-3
GO:0003008 system process 2.236130e-3
GO:0060029 convergent extension involved in organogenesis 2.240399e-3
GO:0016575 histone deacetylation 2.264588e-3
GO:2000172 regulation of branching morphogenesis of a nerve 2.336904e-3
GO:0060359 response to ammonium ion 2.336904e-3
GO:0010624 regulation of Schwann cell proliferation 2.336904e-3
GO:0050920 regulation of chemotaxis 2.347832e-3
GO:0042662 negative regulation of mesodermal cell fate specification 2.398775e-3
GO:0044242 cellular lipid catabolic process 2.424707e-3
GO:0016477 cell migration 2.429565e-3
GO:0033131 regulation of glucokinase activity 2.434973e-3
GO:0034421 post-translational protein acetylation 2.461518e-3
GO:0021915 neural tube development 2.463680e-3
GO:0032656 regulation of interleukin-13 production 2.478163e-3
GO:0051608 histamine transport 2.534382e-3
GO:0001707 mesoderm formation 2.564305e-3
GO:0015914 phospholipid transport 2.583702e-3
GO:0031558 induction of apoptosis in response to chemical stimulus 2.628403e-3
GO:0071287 cellular response to manganese ion 2.628403e-3
GO:0051085 chaperone mediated protein folding requiring cofactor 2.630705e-3
GO:0018958 phenol-containing compound metabolic process 2.642602e-3
GO:0019722 calcium-mediated signaling 2.712146e-3
GO:0006145 purine base catabolic process 2.739812e-3
GO:0002687 positive regulation of leukocyte migration 2.767659e-3
GO:0001777 T cell homeostatic proliferation 2.799780e-3
GO:0034770 histone H4-K20 methylation 2.832402e-3
GO:0048513 organ development 2.861433e-3
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 2.884726e-3
GO:0043181 vacuolar sequestering 2.888306e-3
GO:0032383 regulation of intracellular cholesterol transport 2.888306e-3
GO:0001811 negative regulation of type I hypersensitivity 2.888306e-3
GO:0002638 negative regulation of immunoglobulin production 2.888306e-3
GO:0051917 regulation of fibrinolysis 2.950692e-3
GO:0061037 negative regulation of cartilage development 2.970826e-3
GO:0048016 inositol phosphate-mediated signaling 2.979953e-3
GO:2000227 negative regulation of pancreatic A cell differentiation 2.983908e-3
GO:2000978 negative regulation of forebrain neuron differentiation 2.983908e-3
GO:0061106 negative regulation of stomach neuroendocrine cell differentiation 2.983908e-3
GO:0046331 lateral inhibition 2.983908e-3
GO:0048597 post-embryonic camera-type eye morphogenesis 2.983908e-3
GO:0050918 positive chemotaxis 2.992418e-3
GO:0002688 regulation of leukocyte chemotaxis 2.996597e-3
GO:0061002 negative regulation of dendritic spine morphogenesis 3.025986e-3
GO:0043420 anthranilate metabolic process 3.072476e-3
GO:0050861 positive regulation of B cell receptor signaling pathway 3.072476e-3
GO:0034516 response to vitamin B6 3.072476e-3
GO:0002430 complement receptor mediated signaling pathway 3.072476e-3
GO:0043462 regulation of ATPase activity 3.145498e-3
GO:0003230 cardiac atrium development 3.165372e-3
GO:0006939 smooth muscle contraction 3.215021e-3
GO:0045619 regulation of lymphocyte differentiation 3.252948e-3
GO:0051496 positive regulation of stress fiber assembly 3.256527e-3
GO:0002251 organ or tissue specific immune response 3.264714e-3
GO:0051336 regulation of hydrolase activity 3.356419e-3
GO:0050818 regulation of coagulation 3.385672e-3
GO:0060068 vagina development 3.391306e-3
GO:0010898 positive regulation of triglyceride catabolic process 3.402448e-3
GO:0001505 regulation of neurotransmitter levels 3.408106e-3
GO:0002572 pro-T cell differentiation 3.428985e-3
GO:0050996 positive regulation of lipid catabolic process 3.442618e-3
GO:0031345 negative regulation of cell projection organization 3.524403e-3
GO:0050801 ion homeostasis 3.573888e-3
GO:0048144 fibroblast proliferation 3.711761e-3
GO:0035725 sodium ion transmembrane transport 3.716780e-3
GO:0051901 positive regulation of mitochondrial depolarization 3.739019e-3
GO:0031579 membrane raft organization 3.763018e-3
GO:0010350 cellular response to magnesium starvation 3.785919e-3
GO:0007340 acrosome reaction 3.795627e-3
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 3.827984e-3
GO:0035094 response to nicotine 3.844164e-3
GO:0030048 actin filament-based movement 3.844164e-3
GO:0010518 positive regulation of phospholipase activity 3.892285e-3
GO:0046847 filopodium assembly 3.918147e-3
GO:0010951 negative regulation of endopeptidase activity 4.024809e-3
GO:0071242 cellular response to ammonium ion 4.038928e-3
GO:0051918 negative regulation of fibrinolysis 4.045739e-3
GO:0050710 negative regulation of cytokine secretion 4.056604e-3
GO:0006704 glucocorticoid biosynthetic process 4.077509e-3
GO:0072182 regulation of nephron tubule epithelial cell differentiation 4.223896e-3
GO:0016055 Wnt receptor signaling pathway 4.260256e-3
GO:0046031 ADP metabolic process 4.283959e-3
GO:0007527 adult somatic muscle development 4.295869e-3
GO:0044240 multicellular organismal lipid catabolic process 4.318692e-3
GO:0043954 cellular component maintenance 4.419253e-3
GO:2000273 positive regulation of receptor activity 4.419253e-3
GO:0052548 regulation of endopeptidase activity 4.450670e-3
GO:0030509 BMP signaling pathway 4.523783e-3
GO:0001906 cell killing 4.556816e-3
GO:0042157 lipoprotein metabolic process 4.566867e-3
GO:2000043 regulation of cardiac cell fate specification 4.593309e-3
GO:0070367 negative regulation of hepatocyte differentiation 4.616354e-3
GO:0021501 prechordal plate formation 4.616354e-3
GO:0021547 midbrain-hindbrain boundary initiation 4.616354e-3
GO:0019725 cellular homeostasis 4.636969e-3
GO:0034097 response to cytokine stimulus 4.647271e-3
GO:0009132 nucleoside diphosphate metabolic process 4.726839e-3
GO:0046653 tetrahydrofolate metabolic process 4.728110e-3
GO:0045833 negative regulation of lipid metabolic process 4.737008e-3
GO:0050917 sensory perception of umami taste 4.741076e-3
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 4.885381e-3
GO:0060480 lung goblet cell differentiation 4.885381e-3
GO:0010611 regulation of cardiac muscle hypertrophy 4.886372e-3
GO:0010989 negative regulation of low-density lipoprotein particle clearance 4.914465e-3
GO:0006760 folic acid-containing compound metabolic process 4.951239e-3
GO:0060841 venous blood vessel development 4.960797e-3
GO:0061326 renal tubule development 5.013260e-3
GO:0048489 synaptic vesicle transport 5.043564e-3
GO:0048870 cell motility 5.105548e-3
GO:0051656 establishment of organelle localization 5.145333e-3
GO:0010638 positive regulation of organelle organization 5.146969e-3
GO:0032844 regulation of homeostatic process 5.261497e-3
GO:0035814 negative regulation of renal sodium excretion 5.324152e-3
GO:0051602 response to electrical stimulus 5.368274e-3
GO:0035121 tail morphogenesis 5.369774e-3
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 5.387925e-3
GO:0035813 regulation of renal sodium excretion 5.390544e-3
GO:0043434 response to peptide hormone stimulus 5.505051e-3
GO:0060627 regulation of vesicle-mediated transport 5.508982e-3
GO:0032836 glomerular basement membrane development 5.511302e-3
GO:0071316 cellular response to nicotine 5.511302e-3
GO:0009972 cytidine deamination 5.511302e-3
GO:0002507 tolerance induction 5.538235e-3
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 5.582139e-3
GO:0043406 positive regulation of MAP kinase activity 5.601325e-3
GO:0032674 regulation of interleukin-5 production 5.615846e-3
GO:0014743 regulation of muscle hypertrophy 5.615846e-3
GO:0085029 extracellular matrix assembly 5.654362e-3
GO:0042035 regulation of cytokine biosynthetic process 5.702327e-3
GO:0009258 10-formyltetrahydrofolate catabolic process 5.738922e-3
GO:0072337 modified amino acid transport 5.741887e-3
GO:0070307 lens fiber cell development 5.743327e-3
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 5.767065e-3
GO:0002115 store-operated calcium entry 5.767065e-3
GO:0006941 striated muscle contraction 5.847240e-3
GO:0006507 GPI anchor release 5.852559e-3
GO:0060807 regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification 5.852559e-3
GO:0003142 cardiogenic plate morphogenesis 5.852559e-3
GO:0001828 inner cell mass cellular morphogenesis 5.852559e-3
GO:0009435 NAD biosynthetic process 5.859169e-3
GO:0009612 response to mechanical stimulus 5.878115e-3
GO:0051055 negative regulation of lipid biosynthetic process 5.908151e-3
GO:0006694 steroid biosynthetic process 5.942785e-3
GO:0060913 cardiac cell fate determination 5.943137e-3
GO:0030001 metal ion transport 5.960999e-3
GO:0032869 cellular response to insulin stimulus 6.032884e-3
GO:0032754 positive regulation of interleukin-5 production 6.117746e-3
GO:0070933 histone H4 deacetylation 6.145784e-3