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Novel motif:35

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name:motif35_CGCCYAGA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0006353 transcription termination, DNA-dependent 5.088230e-15
GO:2000465 regulation of glycogen (starch) synthase activity 3.373640e-14
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 3.173736e-13
GO:0046628 positive regulation of insulin receptor signaling pathway 1.172120e-11
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 1.437238e-11
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 1.437238e-11
GO:0090002 establishment of protein localization in plasma membrane 3.061622e-11
GO:0072661 protein targeting to plasma membrane 3.283383e-11
GO:2000467 positive regulation of glycogen (starch) synthase activity 3.416956e-11
GO:0006369 termination of RNA polymerase II transcription 1.422646e-10
GO:0006406 mRNA export from nucleus 9.167526e-10
GO:0051645 Golgi localization 2.083733e-9
GO:0001522 pseudouridine synthesis 7.177801e-9
GO:0000244 assembly of spliceosomal tri-snRNP 1.665819e-8
GO:0005979 regulation of glycogen biosynthetic process 3.044450e-8
GO:0090150 establishment of protein localization in membrane 4.299723e-8
GO:0090031 positive regulation of steroid hormone biosynthetic process 8.845634e-8
GO:0070873 regulation of glycogen metabolic process 1.001354e-7
GO:2000273 positive regulation of receptor activity 1.837889e-7
GO:0071585 detoxification of cadmium ion 2.138967e-7
GO:0045653 negative regulation of megakaryocyte differentiation 3.064017e-7
GO:0042254 ribosome biogenesis 3.121290e-7
GO:0022027 interkinetic nuclear migration 3.508368e-7
GO:0065002 intracellular protein transmembrane transport 4.507341e-7
GO:0006364 rRNA processing 5.198339e-7
GO:0016072 rRNA metabolic process 5.228521e-7
GO:0006405 RNA export from nucleus 6.266424e-7
GO:0048075 positive regulation of eye pigmentation 7.910414e-7
GO:0031017 exocrine pancreas development 1.159487e-6
GO:0021506 anterior neuropore closure 1.286099e-6
GO:0006349 regulation of gene expression by genetic imprinting 1.678748e-6
GO:0035095 behavioral response to nicotine 2.159136e-6
GO:0042104 positive regulation of activated T cell proliferation 2.202717e-6
GO:0090281 negative regulation of calcium ion import 2.320005e-6
GO:0071584 negative regulation of zinc ion import 2.320005e-6
GO:0006779 porphyrin-containing compound biosynthetic process 2.946332e-6
GO:0032468 Golgi calcium ion homeostasis 3.498494e-6
GO:0032472 Golgi calcium ion transport 3.498494e-6
GO:0030026 cellular manganese ion homeostasis 3.498494e-6
GO:0060040 retinal bipolar neuron differentiation 5.526380e-6
GO:0019478 D-amino acid catabolic process 5.621570e-6
GO:0045725 positive regulation of glycogen biosynthetic process 6.219687e-6
GO:0035329 hippo signaling cascade 7.378938e-6
GO:0090305 nucleic acid phosphodiester bond hydrolysis 8.855570e-6
GO:0002115 store-operated calcium entry 1.010585e-5
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 1.158608e-5
GO:0035090 maintenance of apical/basal cell polarity 1.222760e-5
GO:0046416 D-amino acid metabolic process 1.243085e-5
GO:0034660 ncRNA metabolic process 1.456745e-5
GO:0022613 ribonucleoprotein complex biogenesis 1.520080e-5
GO:0046105 thymidine biosynthetic process 1.771466e-5
GO:0034766 negative regulation of ion transmembrane transport 1.771466e-5
GO:0034080 CenH3-containing nucleosome assembly at centromere 1.779526e-5
GO:0070875 positive regulation of glycogen metabolic process 1.815171e-5
GO:0006361 transcription initiation from RNA polymerase I promoter 1.818650e-5
GO:0050983 deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase 1.864829e-5
GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation 1.864829e-5
GO:0006013 mannose metabolic process 1.986925e-5
GO:0000387 spliceosomal snRNP assembly 1.991171e-5
GO:0048073 regulation of eye pigmentation 2.193691e-5
GO:0046006 regulation of activated T cell proliferation 2.229099e-5
GO:0071168 protein localization to chromatin 2.305995e-5
GO:0060084 synaptic transmission involved in micturition 2.374775e-5
GO:0006760 folic acid-containing compound metabolic process 2.845432e-5
GO:0043467 regulation of generation of precursor metabolites and energy 3.005216e-5
GO:0034241 positive regulation of macrophage fusion 3.059380e-5
GO:0031119 tRNA pseudouridine synthesis 3.059380e-5
GO:0006363 termination of RNA polymerase I transcription 3.282001e-5
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 3.409411e-5
GO:0006281 DNA repair 3.502963e-5
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.516267e-5
GO:0021623 oculomotor nerve formation 3.546262e-5
GO:0003409 optic cup structural organization 3.546262e-5
GO:0003404 optic vesicle morphogenesis 3.546262e-5
GO:0060160 negative regulation of dopamine receptor signaling pathway 3.728533e-5
GO:0006335 DNA replication-dependent nucleosome assembly 3.728533e-5
GO:2000077 negative regulation of type B pancreatic cell development 4.162488e-5
GO:0006545 glycine biosynthetic process 4.545347e-5
GO:0006308 DNA catabolic process 4.784061e-5
GO:0006289 nucleotide-excision repair 5.308363e-5
GO:0046886 positive regulation of hormone biosynthetic process 5.359958e-5
GO:0051647 nucleus localization 5.867626e-5
GO:2000466 negative regulation of glycogen (starch) synthase activity 6.165405e-5
GO:0070935 3'-UTR-mediated mRNA stabilization 6.563315e-5
GO:0006778 porphyrin-containing compound metabolic process 7.785746e-5
GO:0032581 ER-dependent peroxisome organization 8.041920e-5
GO:0085020 protein K6-linked ubiquitination 8.343123e-5
GO:0045652 regulation of megakaryocyte differentiation 9.956654e-5
GO:0007020 microtubule nucleation 9.998043e-5
GO:0019264 glycine biosynthetic process from serine 1.029065e-4
GO:0006260 DNA replication 1.045721e-4
GO:0050779 RNA destabilization 1.083638e-4
GO:0051793 medium-chain fatty acid catabolic process 1.123192e-4
GO:0031118 rRNA pseudouridine synthesis 1.123192e-4
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.123192e-4
GO:0032007 negative regulation of TOR signaling cascade 1.144958e-4
GO:0045358 negative regulation of interferon-beta biosynthetic process 1.145239e-4
GO:0010509 polyamine homeostasis 1.145239e-4
GO:0006427 histidyl-tRNA aminoacylation 1.145239e-4
GO:0010907 positive regulation of glucose metabolic process 1.171925e-4
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 1.452284e-4
GO:0031047 gene silencing by RNA 1.677016e-4
GO:0033119 negative regulation of RNA splicing 1.728430e-4
GO:0006390 transcription from mitochondrial promoter 1.765143e-4
GO:0010621 negative regulation of transcription by transcription factor localization 1.822709e-4
GO:0071281 cellular response to iron ion 1.825051e-4
GO:0006783 heme biosynthetic process 1.842327e-4
GO:0035166 post-embryonic hemopoiesis 1.906674e-4
GO:0006598 polyamine catabolic process 2.074211e-4
GO:0006359 regulation of transcription from RNA polymerase III promoter 2.092692e-4
GO:0032933 SREBP-mediated signaling pathway 2.326089e-4
GO:0016338 calcium-independent cell-cell adhesion 2.387269e-4
GO:0008216 spermidine metabolic process 2.576265e-4
GO:0031055 chromatin remodeling at centromere 2.676275e-4
GO:0035104 positive regulation of transcription via sterol regulatory element binding 2.680799e-4
GO:0034470 ncRNA processing 2.748182e-4
GO:0033013 tetrapyrrole metabolic process 2.881162e-4
GO:0001830 trophectodermal cell fate commitment 2.891424e-4
GO:0050720 interleukin-1 beta biosynthetic process 2.922661e-4
GO:0018009 N-terminal peptidyl-L-cysteine N-palmitoylation 2.922661e-4
GO:0061157 mRNA destabilization 3.057372e-4
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 3.057372e-4
GO:0002536 respiratory burst involved in inflammatory response 3.057372e-4
GO:0045047 protein targeting to ER 3.195977e-4
GO:2000378 negative regulation of reactive oxygen species metabolic process 3.318480e-4
GO:0021603 cranial nerve formation 3.464538e-4
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 3.496063e-4
GO:0061032 visceral serous pericardium development 3.496063e-4
GO:0043276 anoikis 3.496063e-4
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 3.553616e-4
GO:0071843 cellular component biogenesis at cellular level 3.797940e-4
GO:0071169 establishment of protein localization to chromatin 3.867839e-4
GO:0030262 apoptotic nuclear change 3.997052e-4
GO:0042168 heme metabolic process 4.006047e-4
GO:0006228 UTP biosynthetic process 4.073914e-4
GO:0006183 GTP biosynthetic process 4.073914e-4
GO:0006165 nucleoside diphosphate phosphorylation 4.073914e-4
GO:0051168 nuclear export 4.124149e-4
GO:0002679 respiratory burst involved in defense response 4.141761e-4
GO:0046796 viral genome transport in host cell 4.277889e-4
GO:0000578 embryonic axis specification 4.345339e-4
GO:0006707 cholesterol catabolic process 4.365525e-4
GO:0051028 mRNA transport 4.525050e-4
GO:0071514 genetic imprinting 4.576284e-4
GO:0006544 glycine metabolic process 4.939548e-4
GO:0051313 attachment of spindle microtubules to chromosome 5.007617e-4
GO:0018206 peptidyl-methionine modification 5.334332e-4
GO:0006379 mRNA cleavage 5.382007e-4
GO:0021528 commissural neuron differentiation in spinal cord 5.432992e-4
GO:0048298 positive regulation of isotype switching to IgA isotypes 5.466784e-4
GO:0061011 hepatic duct development 5.557327e-4
GO:0006348 chromatin silencing at telomere 5.557327e-4
GO:0000718 nucleotide-excision repair, DNA damage removal 5.593957e-4
GO:0046015 regulation of transcription by glucose 5.959375e-4
GO:0010676 positive regulation of cellular carbohydrate metabolic process 5.979169e-4
GO:0090307 spindle assembly involved in mitosis 5.985330e-4
GO:0045199 maintenance of epithelial cell apical/basal polarity 6.276367e-4
GO:2000188 regulation of cholesterol homeostasis 6.276367e-4
GO:0015884 folic acid transport 6.489757e-4
GO:0006391 transcription initiation from mitochondrial promoter 6.634887e-4
GO:0002502 peptide antigen assembly with MHC class I protein complex 6.634887e-4
GO:0032288 myelin assembly 6.881166e-4
GO:0010266 response to vitamin B1 7.033008e-4
GO:0007194 negative regulation of adenylate cyclase activity 7.138989e-4
GO:0006290 pyrimidine dimer repair 7.437662e-4
GO:0000154 rRNA modification 7.437662e-4
GO:0031442 positive regulation of mRNA 3'-end processing 7.502687e-4
GO:0033239 negative regulation of cellular amine metabolic process 7.603723e-4
GO:0006398 histone mRNA 3'-end processing 7.604722e-4
GO:0001916 positive regulation of T cell mediated cytotoxicity 7.658570e-4
GO:0032392 DNA geometric change 7.713391e-4
GO:0007051 spindle organization 7.773542e-4
GO:0006481 C-terminal protein methylation 8.001092e-4
GO:0051350 negative regulation of lyase activity 8.061689e-4
GO:0043985 histone H4-R3 methylation 8.226360e-4
GO:0044319 wound healing, spreading of cells 8.277542e-4
GO:0042274 ribosomal small subunit biogenesis 8.289832e-4
GO:0006360 transcription from RNA polymerase I promoter 9.154188e-4
GO:0035088 establishment or maintenance of apical/basal cell polarity 9.273154e-4
GO:0045454 cell redox homeostasis 9.330295e-4
GO:0043089 positive regulation of Cdc42 GTPase activity 9.659111e-4
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 9.666050e-4
GO:0007354 zygotic determination of anterior/posterior axis, embryo 9.994955e-4
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 1.015758e-3
GO:0046939 nucleotide phosphorylation 1.054661e-3
GO:0035313 wound healing, spreading of epidermal cells 1.055164e-3
GO:0046426 negative regulation of JAK-STAT cascade 1.060273e-3
GO:0006362 transcription elongation from RNA polymerase I promoter 1.067278e-3
GO:0016598 protein arginylation 1.073411e-3
GO:0071934 thiamine transmembrane transport 1.073411e-3
GO:0006682 galactosylceramide biosynthetic process 1.073411e-3
GO:0009650 UV protection 1.084345e-3
GO:0006241 CTP biosynthetic process 1.101375e-3
GO:0042732 D-xylose metabolic process 1.120186e-3
GO:0070535 histone H2A K63-linked ubiquitination 1.120186e-3
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 1.120186e-3
GO:0009589 detection of UV 1.120186e-3
GO:0071415 cellular response to purine-containing compound 1.163841e-3
GO:0046108 uridine metabolic process 1.163841e-3
GO:0010225 response to UV-C 1.164353e-3
GO:0016048 detection of temperature stimulus 1.216694e-3
GO:0006268 DNA unwinding involved in replication 1.219822e-3
GO:0006491 N-glycan processing 1.258986e-3
GO:0016973 poly(A)+ mRNA export from nucleus 1.266229e-3
GO:0032205 negative regulation of telomere maintenance 1.278825e-3
GO:0044258 intestinal lipid catabolic process 1.312987e-3
GO:0018350 protein esterification 1.312987e-3
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 1.423865e-3
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway 1.546785e-3
GO:0070574 cadmium ion transmembrane transport 1.555995e-3
GO:0046655 folic acid metabolic process 1.586057e-3
GO:0016570 histone modification 1.637584e-3
GO:0032508 DNA duplex unwinding 1.639881e-3
GO:0048102 autophagic cell death 1.677319e-3
GO:0030237 female sex determination 1.690819e-3
GO:0030953 astral microtubule organization 1.749060e-3
GO:0018345 protein palmitoylation 1.775344e-3
GO:0051256 spindle midzone assembly involved in mitosis 1.784911e-3
GO:0010906 regulation of glucose metabolic process 1.786243e-3
GO:0008049 male courtship behavior 1.797859e-3
GO:0006479 protein methylation 1.808106e-3
GO:0060042 retina morphogenesis in camera-type eye 1.818668e-3
GO:0032239 regulation of nucleobase-containing compound transport 2.044188e-3
GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway 2.052378e-3
GO:0016191 synaptic vesicle uncoating 2.086093e-3
GO:0007100 mitotic centrosome separation 2.086093e-3
GO:0006284 base-excision repair 2.086851e-3
GO:0035873 lactate transmembrane transport 2.156427e-3
GO:0001302 replicative cell aging 2.196364e-3
GO:0040029 regulation of gene expression, epigenetic 2.206970e-3
GO:0016571 histone methylation 2.258734e-3
GO:0043255 regulation of carbohydrate biosynthetic process 2.259761e-3
GO:0071157 negative regulation of cell cycle arrest 2.283115e-3
GO:0007000 nucleolus organization 2.302948e-3
GO:0006283 transcription-coupled nucleotide-excision repair 2.306863e-3
GO:0006302 double-strand break repair 2.314089e-3
GO:0034723 DNA replication-dependent nucleosome organization 2.328961e-3
GO:0048733 sebaceous gland development 2.368384e-3
GO:0030718 germ-line stem cell maintenance 2.368384e-3
GO:0090141 positive regulation of mitochondrial fission 2.371635e-3
GO:0000089 mitotic metaphase 2.435091e-3
GO:0090230 regulation of centromere complex assembly 2.512120e-3
GO:0032352 positive regulation of hormone metabolic process 2.671021e-3
GO:0010944 negative regulation of transcription by competitive promoter binding 2.704522e-3
GO:0045014 negative regulation of transcription by glucose 2.723460e-3
GO:0010985 negative regulation of lipoprotein particle clearance 2.786151e-3
GO:0060455 negative regulation of gastric acid secretion 2.799065e-3
GO:0045656 negative regulation of monocyte differentiation 2.799065e-3
GO:0048050 post-embryonic eye morphogenesis 2.799065e-3
GO:0034587 piRNA metabolic process 2.825086e-3
GO:0046039 GTP metabolic process 2.854850e-3
GO:0008334 histone mRNA metabolic process 2.870319e-3
GO:0060998 regulation of dendritic spine development 2.896072e-3
GO:0031848 protection from non-homologous end joining at telomere 2.950774e-3
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 2.950774e-3
GO:0009798 axis specification 2.987611e-3
GO:0010988 regulation of low-density lipoprotein particle clearance 3.008204e-3
GO:0044314 protein K27-linked ubiquitination 3.034044e-3
GO:0045792 negative regulation of cell size 3.043554e-3
GO:0060041 retina development in camera-type eye 3.134216e-3
GO:0003334 keratinocyte development 3.138838e-3
GO:0061002 negative regulation of dendritic spine morphogenesis 3.179827e-3
GO:0042558 pteridine-containing compound metabolic process 3.223832e-3
GO:0006984 ER-nucleus signaling pathway 3.279031e-3
GO:0030828 positive regulation of cGMP biosynthetic process 3.345507e-3
GO:0070979 protein K11-linked ubiquitination 3.474071e-3
GO:0016569 covalent chromatin modification 3.536091e-3
GO:0006529 asparagine biosynthetic process 3.587832e-3
GO:2000189 positive regulation of cholesterol homeostasis 3.610181e-3
GO:0090234 regulation of kinetochore assembly 3.633644e-3
GO:0090169 regulation of spindle assembly 3.633644e-3
GO:2000251 positive regulation of actin cytoskeleton reorganization 3.842228e-3
GO:0042255 ribosome assembly 3.873808e-3
GO:0034969 histone arginine methylation 3.879697e-3
GO:0009070 serine family amino acid biosynthetic process 3.889946e-3
GO:0071034 CUT catabolic process 3.990969e-3
GO:0042711 maternal behavior 3.995911e-3
GO:0071476 cellular hypotonic response 4.022257e-3
GO:0031268 pseudopodium organization 4.086112e-3
GO:0071307 cellular response to vitamin K 4.149650e-3
GO:0050904 diapedesis 4.149650e-3
GO:0048291 isotype switching to IgG isotypes 4.149650e-3
GO:0071403 cellular response to high density lipoprotein particle stimulus 4.149650e-3
GO:0071423 malate transmembrane transport 4.149650e-3
GO:0071448 cellular response to alkyl hydroperoxide 4.149650e-3
GO:0071315 cellular response to morphine 4.149650e-3
GO:0002842 positive regulation of T cell mediated immune response to tumor cell 4.149650e-3
GO:0002368 B cell cytokine production 4.149650e-3
GO:0031269 pseudopodium assembly 4.149650e-3
GO:0006756 AMP phosphorylation 4.149650e-3
GO:0014739 positive regulation of muscle hyperplasia 4.149650e-3
GO:0018364 peptidyl-glutamine methylation 4.149650e-3
GO:0015709 thiosulfate transport 4.149650e-3
GO:0070943 neutrophil mediated killing of symbiont cell 4.155657e-3
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 4.232618e-3
GO:0043966 histone H3 acetylation 4.270398e-3
GO:0051545 negative regulation of elastin biosynthetic process 4.318908e-3
GO:0043543 protein acylation 4.349438e-3
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.397962e-3
GO:0070946 neutrophil mediated killing of gram-positive bacterium 4.609669e-3
GO:0042766 nucleosome mobilization 4.609669e-3
GO:0060716 labyrinthine layer blood vessel development 4.792970e-3
GO:0051255 spindle midzone assembly 4.795312e-3
GO:0065001 specification of axis polarity 4.841141e-3
GO:0006600 creatine metabolic process 4.870926e-3
GO:0048149 behavioral response to ethanol 5.027700e-3
GO:0032525 somite rostral/caudal axis specification 5.071723e-3
GO:0046513 ceramide biosynthetic process 5.116171e-3
GO:2000971 negative regulation of detection of glucose 5.142496e-3
GO:2000976 regulation of transcription from RNA polymerase II promoter involved in detection of glucose 5.142496e-3
GO:0000433 negative regulation of transcription from RNA polymerase II promoter by glucose 5.142496e-3
GO:0035357 peroxisome proliferator activated receptor signaling pathway 5.211652e-3
GO:0010984 regulation of lipoprotein particle clearance 5.221644e-3
GO:0050689 negative regulation of defense response to virus by host 5.235658e-3
GO:0071539 protein localization to centrosome 5.388445e-3
GO:0007271 synaptic transmission, cholinergic 5.404911e-3
GO:0006386 termination of RNA polymerase III transcription 5.435969e-3
GO:0051131 chaperone-mediated protein complex assembly 5.435969e-3
GO:0006385 transcription elongation from RNA polymerase III promoter 5.435969e-3
GO:0000375 RNA splicing, via transesterification reactions 5.539248e-3
GO:0060060 post-embryonic retina morphogenesis in camera-type eye 5.550084e-3
GO:0034633 retinol transport 5.550084e-3
GO:0070172 positive regulation of tooth mineralization 5.600245e-3
GO:0000398 nuclear mRNA splicing, via spliceosome 5.601144e-3
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 5.612112e-3
GO:0035461 vitamin transmembrane transport 5.637345e-3
GO:0006498 N-terminal protein lipidation 5.637345e-3
GO:0033132 negative regulation of glucokinase activity 5.641365e-3
GO:0000415 negative regulation of histone H3-K36 methylation 5.641365e-3
GO:0032864 activation of Cdc42 GTPase activity 5.641365e-3
GO:0008595 anterior/posterior axis specification, embryo 5.760154e-3
GO:0033314 mitotic cell cycle DNA replication checkpoint 5.787950e-3
GO:0043088 regulation of Cdc42 GTPase activity 5.885230e-3
GO:0016574 histone ubiquitination 6.003117e-3
GO:0046831 regulation of RNA export from nucleus 6.075569e-3
GO:2001076 positive regulation of metanephric ureteric bud development 6.237942e-3
GO:0007356 thorax and anterior abdomen determination 6.237942e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 6.385268e-3
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 6.456158e-3
GO:0009253 peptidoglycan catabolic process 6.500754e-3
GO:0015813 L-glutamate transport 6.548987e-3
GO:0051005 negative regulation of lipoprotein lipase activity 6.606766e-3
GO:0000723 telomere maintenance 6.620377e-3
GO:0048569 post-embryonic organ development 6.743610e-3
GO:0007090 regulation of S phase of mitotic cell cycle 6.803819e-3
GO:0048561 establishment of organ orientation 6.837221e-3
GO:0046078 dUMP metabolic process 6.837221e-3
GO:0019323 pentose catabolic process 6.837221e-3
GO:0032241 positive regulation of nucleobase-containing compound transport 6.837221e-3
GO:0051546 keratinocyte migration 6.890038e-3
GO:0070874 negative regulation of glycogen metabolic process 6.916479e-3
GO:0010701 positive regulation of norepinephrine secretion 7.234505e-3
GO:0016075 rRNA catabolic process 7.340417e-3
GO:0070170 regulation of tooth mineralization 7.439250e-3
GO:0060179 male mating behavior 7.471264e-3
GO:0032287 peripheral nervous system myelin maintenance 7.546353e-3
GO:0008292 acetylcholine biosynthetic process 7.546353e-3
GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions 7.546353e-3
GO:0016233 telomere capping 7.738287e-3
GO:0009304 tRNA transcription 7.738287e-3
GO:0071469 cellular response to alkalinity 7.987421e-3
GO:2000009 negative regulation of protein localization at cell surface 7.987421e-3
GO:0001519 peptide amidation 7.987421e-3
GO:0046079 dUMP catabolic process 7.987421e-3
GO:0043456 regulation of pentose-phosphate shunt 7.987421e-3
GO:0031860 telomeric 3' overhang formation 7.987421e-3
GO:0005978 glycogen biosynthetic process 8.006860e-3
GO:0007029 endoplasmic reticulum organization 8.016484e-3
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 8.069485e-3
GO:0045719 negative regulation of glycogen biosynthetic process 8.086258e-3
GO:0006370 mRNA capping 8.148559e-3
GO:0048268 clathrin coat assembly 8.387220e-3
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion 8.425411e-3
GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein 8.425411e-3
GO:0006334 nucleosome assembly 8.462382e-3
GO:0051135 positive regulation of NK T cell activation 8.478129e-3
GO:0045556 positive regulation of TRAIL biosynthetic process 8.720904e-3
GO:0009451 RNA modification 8.827632e-3
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 8.857735e-3
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 8.857735e-3
GO:0035871 protein K11-linked deubiquitination 8.857735e-3
GO:0034699 response to luteinizing hormone stimulus 8.857735e-3
GO:0007009 plasma membrane organization 8.990128e-3
GO:0001705 ectoderm formation 9.248944e-3
GO:0050965 detection of temperature stimulus involved in sensory perception of pain 9.271410e-3
GO:0019254 carnitine metabolic process, CoA-linked 9.271410e-3
GO:0032383 regulation of intracellular cholesterol transport 9.271410e-3
GO:0009437 carnitine metabolic process 9.388695e-3
GO:0000959 mitochondrial RNA metabolic process 9.445627e-3
GO:0060421 positive regulation of heart growth 9.449377e-3
GO:0006109 regulation of carbohydrate metabolic process 9.509721e-3
GO:0043486 histone exchange 9.558424e-3
GO:0071816 tail-anchored membrane protein insertion into ER membrane 9.594640e-3
GO:0072659 protein localization in plasma membrane 9.634526e-3
GO:0002432 granuloma formation 9.737679e-3
GO:0006533 aspartate catabolic process 9.737679e-3
GO:0070972 protein localization in endoplasmic reticulum 9.949748e-3
GO:0043060 meiotic metaphase I plate congression 1.005319e-2
GO:0010900 negative regulation of phosphatidylcholine catabolic process 1.005319e-2
GO:0042506 tyrosine phosphorylation of Stat5 protein 1.006831e-2
GO:0048239 negative regulation of DNA recombination at telomere 1.011907e-2
GO:0006261 DNA-dependent DNA replication 1.034154e-2
GO:0033057 multicellular organismal reproductive behavior 1.042615e-2
GO:0014738 regulation of muscle hyperplasia 1.067987e-2
GO:0009132 nucleoside diphosphate metabolic process 1.094757e-2
GO:0016576 histone dephosphorylation 1.110525e-2
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 1.123532e-2
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 1.123532e-2
GO:0060829 negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation 1.130856e-2
GO:0051791 medium-chain fatty acid metabolic process 1.130856e-2
GO:0071279 cellular response to cobalt ion 1.130856e-2
GO:0008616 queuosine biosynthetic process 1.130856e-2
GO:0010637 negative regulation of mitochondrial fusion 1.130856e-2
GO:0000354 cis assembly of pre-catalytic spliceosome 1.130856e-2
GO:0000236 mitotic prometaphase 1.134467e-2
GO:0050847 progesterone receptor signaling pathway 1.164702e-2
GO:0006659 phosphatidylserine biosynthetic process 1.170920e-2
GO:0001982 baroreceptor response to decreased systemic arterial blood pressure 1.172697e-2
GO:0000492 box C/D snoRNP assembly 1.172697e-2
GO:0018216 peptidyl-arginine methylation 1.189212e-2
GO:0051225 spindle assembly 1.190090e-2
GO:0048842 positive regulation of axon extension involved in axon guidance 1.234733e-2
GO:0021526 medial motor column neuron differentiation 1.234733e-2
GO:0060159 regulation of dopamine receptor signaling pathway 1.246547e-2
GO:0046586 regulation of calcium-dependent cell-cell adhesion 1.249751e-2
GO:0046929 negative regulation of neurotransmitter secretion 1.249751e-2
GO:0002839 positive regulation of immune response to tumor cell 1.267501e-2
GO:0006184 GTP catabolic process 1.270231e-2
GO:0090344 negative regulation of cell aging 1.289565e-2
GO:0010675 regulation of cellular carbohydrate metabolic process 1.294881e-2
GO:0016226 iron-sulfur cluster assembly 1.301450e-2
GO:0000080 G1 phase of mitotic cell cycle 1.306334e-2
GO:0000731 DNA synthesis involved in DNA repair 1.308490e-2
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 1.314595e-2
GO:0007004 telomere maintenance via telomerase 1.320417e-2
GO:0045329 carnitine biosynthetic process 1.321618e-2
GO:0051318 G1 phase 1.331950e-2
GO:0003407 neural retina development 1.343057e-2
GO:0002528 regulation of vascular permeability involved in acute inflammatory response 1.348445e-2
GO:0090232 positive regulation of spindle checkpoint 1.355663e-2
GO:0006564 L-serine biosynthetic process 1.355663e-2
GO:0045007 depurination 1.356613e-2
GO:0035356 cellular triglyceride homeostasis 1.356613e-2
GO:0008057 eye pigment granule organization 1.356613e-2
GO:0006400 tRNA modification 1.384386e-2
GO:0001832 blastocyst growth 1.394116e-2
GO:0060628 regulation of ER to Golgi vesicle-mediated transport 1.402097e-2
GO:0032259 methylation 1.407666e-2
GO:0009948 anterior/posterior axis specification 1.421637e-2
GO:0018205 peptidyl-lysine modification 1.460846e-2
GO:0006931 substrate-dependent cell migration, cell attachment to substrate 1.465245e-2
GO:2000573 positive regulation of DNA biosynthetic process 1.468836e-2
GO:0006383 transcription from RNA polymerase III promoter 1.477646e-2
GO:0035414 negative regulation of catenin import into nucleus 1.482977e-2
GO:0032289 central nervous system myelin formation 1.500808e-2
GO:0008291 acetylcholine metabolic process 1.500808e-2
GO:0006278 RNA-dependent DNA replication 1.509926e-2
GO:0042796 snRNA transcription from RNA polymerase III promoter 1.516573e-2
GO:0042941 D-alanine transport 1.516573e-2
GO:0043381 negative regulation of memory T cell differentiation 1.516573e-2
GO:0042795 snRNA transcription from RNA polymerase II promoter 1.516573e-2
GO:0033617 mitochondrial respiratory chain complex IV assembly 1.516573e-2
GO:0017196 N-terminal peptidyl-methionine acetylation 1.516573e-2
GO:0021764 amygdala development 1.516573e-2
GO:0015800 acidic amino acid transport 1.524887e-2
GO:0051323 metaphase 1.544507e-2
GO:0051457 maintenance of protein location in nucleus 1.546551e-2
GO:0051935 glutamate uptake involved in synaptic transmission 1.560678e-2
GO:0002149 hypochlorous acid biosynthetic process 1.560678e-2
GO:0046884 follicle-stimulating hormone secretion 1.581253e-2
GO:0032275 luteinizing hormone secretion 1.581253e-2
GO:0042703 menstruation 1.581253e-2
GO:0017004 cytochrome complex assembly 1.581253e-2
GO:0019101 female somatic sex determination 1.581253e-2
GO:0033522 histone H2A ubiquitination 1.585145e-2
GO:0043491 protein kinase B signaling cascade 1.591584e-2
GO:0046629 gamma-delta T cell activation 1.624017e-2
GO:0045212 neurotransmitter receptor biosynthetic process 1.624017e-2
GO:0042450 arginine biosynthetic process via ornithine 1.624017e-2
GO:0032223 negative regulation of synaptic transmission, cholinergic 1.624017e-2
GO:0045626 negative regulation of T-helper 1 cell differentiation 1.630958e-2
GO:0072124 regulation of glomerular mesangial cell proliferation 1.641152e-2
GO:0035771 interleukin-4-mediated signaling pathway 1.651072e-2
GO:0072166 posterior mesonephric tubule development 1.651072e-2
GO:0061001 regulation of dendritic spine morphogenesis 1.662599e-2
GO:0045655 regulation of monocyte differentiation 1.663627e-2
GO:0072348 sulfur compound transport 1.674565e-2
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 1.690025e-2
GO:0030187 melatonin biosynthetic process 1.690025e-2
GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway 1.690025e-2
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 1.690025e-2
GO:0009452 RNA capping 1.698774e-2
GO:0045351 type I interferon biosynthetic process 1.701232e-2
GO:0050658 RNA transport 1.780819e-2
GO:0051586 positive regulation of dopamine uptake 1.780992e-2
GO:0048203 vesicle targeting, trans-Golgi to endosome 1.780992e-2
GO:0090140 regulation of mitochondrial fission 1.808730e-2
GO:0060689 cell differentiation involved in salivary gland development 1.808730e-2
GO:0060087 relaxation of vascular smooth muscle 1.808730e-2
GO:0002158 osteoclast proliferation 1.809938e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0045922 negative regulation of fatty acid metabolic process 6.670440e-15
GO:0051005 negative regulation of lipoprotein lipase activity 2.397427e-14
GO:0045717 negative regulation of fatty acid biosynthetic process 2.519692e-14
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 5.878056e-14
GO:0034382 chylomicron remnant clearance 5.690621e-13
GO:0010985 negative regulation of lipoprotein particle clearance 1.049267e-12
GO:0010984 regulation of lipoprotein particle clearance 1.209170e-11
GO:0060192 negative regulation of lipase activity 1.329202e-10
GO:0010987 negative regulation of high-density lipoprotein particle clearance 6.142273e-10
GO:0010897 negative regulation of triglyceride catabolic process 6.142273e-10
GO:0050995 negative regulation of lipid catabolic process 7.140022e-10
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 4.050817e-9
GO:0050823 peptide antigen stabilization 4.050817e-9
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 1.084136e-8
GO:2001076 positive regulation of metanephric ureteric bud development 1.084136e-8
GO:0007356 thorax and anterior abdomen determination 1.084136e-8
GO:0010900 negative regulation of phosphatidylcholine catabolic process 1.419432e-8
GO:0010982 regulation of high-density lipoprotein particle clearance 1.433251e-8
GO:0060620 regulation of cholesterol import 2.101168e-8
GO:0006302 double-strand break repair 3.830419e-8
GO:0010989 negative regulation of low-density lipoprotein particle clearance 4.904057e-8
GO:0060621 negative regulation of cholesterol import 7.299165e-8
GO:0006281 DNA repair 9.583888e-8
GO:0033627 cell adhesion mediated by integrin 1.240810e-7
GO:0035329 hippo signaling cascade 2.895742e-7
GO:0048261 negative regulation of receptor-mediated endocytosis 2.895742e-7
GO:0032375 negative regulation of cholesterol transport 3.406479e-7
GO:0033005 positive regulation of mast cell activation 5.223051e-7
GO:0043306 positive regulation of mast cell degranulation 5.914502e-7
GO:0090086 negative regulation of protein deubiquitination 6.077083e-7
GO:0021506 anterior neuropore closure 6.250828e-7
GO:0051055 negative regulation of lipid biosynthetic process 7.872140e-7
GO:0072125 negative regulation of glomerular mesangial cell proliferation 1.082361e-6
GO:0060696 regulation of phospholipid catabolic process 1.296821e-6
GO:0090084 negative regulation of inclusion body assembly 2.047768e-6
GO:0018924 mandelate metabolic process 2.423230e-6
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 2.552837e-6
GO:0043302 positive regulation of leukocyte degranulation 2.646844e-6
GO:0033239 negative regulation of cellular amine metabolic process 2.961804e-6
GO:0061302 smooth muscle cell-matrix adhesion 3.356980e-6
GO:0072166 posterior mesonephric tubule development 3.718939e-6
GO:0035802 adrenal cortex formation 3.718939e-6
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 5.154764e-6
GO:0051004 regulation of lipoprotein lipase activity 5.400665e-6
GO:0031576 G2/M transition checkpoint 6.364833e-6
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 6.779873e-6
GO:0048259 regulation of receptor-mediated endocytosis 7.237602e-6
GO:0045833 negative regulation of lipid metabolic process 7.622014e-6
GO:0002483 antigen processing and presentation of endogenous peptide antigen 8.405956e-6
GO:0090083 regulation of inclusion body assembly 8.525016e-6
GO:0032717 negative regulation of interleukin-8 production 9.673635e-6
GO:0072124 regulation of glomerular mesangial cell proliferation 9.902684e-6
GO:0050713 negative regulation of interleukin-1 beta secretion 1.066819e-5
GO:0072278 metanephric comma-shaped body morphogenesis 1.104582e-5
GO:0072284 metanephric S-shaped body morphogenesis 1.104582e-5
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 1.145833e-5
GO:0000087 M phase of mitotic cell cycle 1.158138e-5
GO:0072015 glomerular visceral epithelial cell development 1.232555e-5
GO:0034447 very-low-density lipoprotein particle clearance 1.235703e-5
GO:0042304 regulation of fatty acid biosynthetic process 1.236718e-5
GO:0002536 respiratory burst involved in inflammatory response 1.255356e-5
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.255356e-5
GO:0061084 negative regulation of protein refolding 1.333043e-5
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 2.149810e-5
GO:0017196 N-terminal peptidyl-methionine acetylation 2.149810e-5
GO:0016578 histone deubiquitination 2.309138e-5
GO:0033238 regulation of cellular amine metabolic process 2.312757e-5
GO:0048285 organelle fission 2.507058e-5
GO:0018095 protein polyglutamylation 3.178729e-5
GO:0006406 mRNA export from nucleus 3.628784e-5
GO:0000733 DNA strand renaturation 4.452813e-5
GO:0042273 ribosomal large subunit biogenesis 4.983671e-5
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 5.128020e-5
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 5.296360e-5
GO:0007067 mitosis 5.375161e-5
GO:0051168 nuclear export 5.816911e-5
GO:0035850 epithelial cell differentiation involved in kidney development 6.524884e-5
GO:0072112 glomerular visceral epithelial cell differentiation 6.678736e-5
GO:0060923 cardiac muscle cell fate commitment 6.790328e-5
GO:0042254 ribosome biogenesis 7.018507e-5
GO:0006412 translation 7.383608e-5
GO:0000279 M phase 7.457346e-5
GO:0006391 transcription initiation from mitochondrial promoter 7.599772e-5
GO:0071156 regulation of cell cycle arrest 7.816223e-5
GO:0043457 regulation of cellular respiration 8.277457e-5
GO:0016559 peroxisome fission 8.292594e-5
GO:0071072 negative regulation of phospholipid biosynthetic process 8.444351e-5
GO:0071218 cellular response to misfolded protein 8.508280e-5
GO:0001830 trophectodermal cell fate commitment 8.696567e-5
GO:0050658 RNA transport 9.173339e-5
GO:0010498 proteasomal protein catabolic process 9.919561e-5
GO:0060674 placenta blood vessel development 1.052439e-4
GO:0060539 diaphragm development 1.052959e-4
GO:0070508 cholesterol import 1.128775e-4
GO:0006334 nucleosome assembly 1.158532e-4
GO:0031572 G2/M transition DNA damage checkpoint 1.313191e-4
GO:0090224 regulation of spindle organization 1.426310e-4
GO:0034629 cellular protein complex localization 1.493588e-4
GO:0006413 translational initiation 1.516459e-4
GO:0050711 negative regulation of interleukin-1 secretion 1.533308e-4
GO:0070845 polyubiquitinated misfolded protein transport 1.622830e-4
GO:0015746 citrate transport 1.622830e-4
GO:0035520 monoubiquitinated protein deubiquitination 1.668976e-4
GO:0006669 sphinganine-1-phosphate biosynthetic process 1.668976e-4
GO:0006405 RNA export from nucleus 1.669477e-4
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 1.936016e-4
GO:0045401 positive regulation of interleukin-3 biosynthetic process 1.936016e-4
GO:0043304 regulation of mast cell degranulation 2.033290e-4
GO:0071071 regulation of phospholipid biosynthetic process 2.035257e-4
GO:0060911 cardiac cell fate commitment 2.100930e-4
GO:2000195 negative regulation of female gonad development 2.190377e-4
GO:0015820 leucine transport 2.190377e-4
GO:0000075 cell cycle checkpoint 2.256517e-4
GO:0035674 tricarboxylic acid transmembrane transport 2.370890e-4
GO:0006515 misfolded or incompletely synthesized protein catabolic process 2.397060e-4
GO:0016073 snRNA metabolic process 2.568339e-4
GO:0070979 protein K11-linked ubiquitination 2.718090e-4
GO:0090085 regulation of protein deubiquitination 2.984654e-4
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 2.984654e-4
GO:0045964 positive regulation of dopamine metabolic process 3.169383e-4
GO:0006913 nucleocytoplasmic transport 3.426718e-4
GO:0010944 negative regulation of transcription by competitive promoter binding 3.593498e-4
GO:0065004 protein-DNA complex assembly 3.928241e-4
GO:0090042 tubulin deacetylation 3.970679e-4
GO:0070846 Hsp90 deacetylation 3.970679e-4
GO:0001579 medium-chain fatty acid transport 3.970679e-4
GO:0006844 acyl carnitine transport 3.970679e-4
GO:0015761 mannose transport 3.970679e-4
GO:0031503 protein complex localization 4.154208e-4
GO:0032328 alanine transport 4.314577e-4
GO:0002309 T cell proliferation involved in immune response 4.625377e-4
GO:0032784 regulation of transcription elongation, DNA-dependent 4.714450e-4
GO:0090343 positive regulation of cell aging 5.420111e-4
GO:0071824 protein-DNA complex subunit organization 5.489054e-4
GO:0006403 RNA localization 5.497028e-4
GO:0034728 nucleosome organization 5.574032e-4
GO:0045064 T-helper 2 cell differentiation 5.594418e-4
GO:0006235 dTTP biosynthetic process 5.594418e-4
GO:0032218 riboflavin transport 5.594418e-4
GO:0042256 mature ribosome assembly 5.599798e-4
GO:2000194 regulation of female gonad development 5.918237e-4
GO:0010310 regulation of hydrogen peroxide metabolic process 5.918237e-4
GO:0005978 glycogen biosynthetic process 6.026684e-4
GO:0065002 intracellular protein transmembrane transport 6.073673e-4
GO:0042942 D-serine transport 6.073673e-4
GO:0033006 regulation of mast cell activation involved in immune response 6.309038e-4
GO:0031584 activation of phospholipase D activity 6.566912e-4
GO:0021933 radial glia guided migration of cerebellar granule cell 7.164649e-4
GO:0007059 chromosome segregation 7.170319e-4
GO:0007141 male meiosis I 7.217267e-4
GO:0016180 snRNA processing 7.217267e-4
GO:0060712 spongiotrophoblast layer development 8.246333e-4
GO:0051169 nuclear transport 8.411409e-4
GO:0045806 negative regulation of endocytosis 8.427892e-4
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 9.413706e-4
GO:0006695 cholesterol biosynthetic process 9.507100e-4
GO:0051028 mRNA transport 9.670865e-4
GO:0006011 UDP-glucose metabolic process 9.844176e-4
GO:0018206 peptidyl-methionine modification 9.844176e-4
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.025339e-3
GO:2000522 positive regulation of immunological synapse formation 1.025339e-3
GO:0046967 cytosol to ER transport 1.025339e-3
GO:0019060 intracellular transport of viral proteins in host cell 1.025339e-3
GO:0015724 formate transport 1.025339e-3
GO:0042851 L-alanine metabolic process 1.025339e-3
GO:0043366 beta selection 1.068526e-3
GO:0050689 negative regulation of defense response to virus by host 1.152617e-3
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 1.152617e-3
GO:0003241 growth involved in heart morphogenesis 1.152617e-3
GO:0046587 positive regulation of calcium-dependent cell-cell adhesion 1.152617e-3
GO:0022417 protein maturation by protein folding 1.152617e-3
GO:0018192 enzyme active site formation via L-cysteine persulfide 1.152617e-3
GO:0010896 regulation of triglyceride catabolic process 1.161867e-3
GO:0006259 DNA metabolic process 1.212605e-3
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 1.213327e-3
GO:0001935 endothelial cell proliferation 1.255204e-3
GO:0031497 chromatin assembly 1.300644e-3
GO:0006668 sphinganine-1-phosphate metabolic process 1.309375e-3
GO:0072215 regulation of metanephros development 1.469198e-3
GO:0007051 spindle organization 1.593515e-3
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 1.623399e-3
GO:0032786 positive regulation of transcription elongation, DNA-dependent 1.623399e-3
GO:0000959 mitochondrial RNA metabolic process 1.706943e-3
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 1.711042e-3
GO:0007249 I-kappaB kinase/NF-kappaB cascade 1.747735e-3
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.773409e-3
GO:0071103 DNA conformation change 1.783271e-3
GO:0051208 sequestering of calcium ion 1.837309e-3
GO:0045358 negative regulation of interferon-beta biosynthetic process 1.837309e-3
GO:0019047 provirus integration 1.837309e-3
GO:0035313 wound healing, spreading of epidermal cells 1.864881e-3
GO:0002886 regulation of myeloid leukocyte mediated immunity 1.869470e-3
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 1.898640e-3
GO:0007406 negative regulation of neuroblast proliferation 1.915610e-3
GO:0006983 ER overload response 1.967159e-3
GO:0051292 nuclear pore complex assembly 1.979007e-3
GO:0090398 cellular senescence 1.999611e-3
GO:0031129 inductive cell-cell signaling 2.144912e-3
GO:0071104 response to interleukin-9 2.207714e-3
GO:0019348 dolichol metabolic process 2.239998e-3
GO:0050994 regulation of lipid catabolic process 2.297020e-3
GO:0001780 neutrophil homeostasis 2.350852e-3
GO:0032060 bleb assembly 2.365263e-3
GO:0038007 netrin-activated signaling pathway 2.397244e-3
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 2.397244e-3
GO:0021623 oculomotor nerve formation 2.397244e-3
GO:0003404 optic vesicle morphogenesis 2.397244e-3
GO:0003409 optic cup structural organization 2.397244e-3
GO:0006307 DNA dealkylation involved in DNA repair 2.695511e-3
GO:0051301 cell division 2.709844e-3
GO:0046984 regulation of hemoglobin biosynthetic process 2.899179e-3
GO:0010508 positive regulation of autophagy 2.952552e-3
GO:0006333 chromatin assembly or disassembly 3.007929e-3
GO:0042996 regulation of Golgi to plasma membrane protein transport 3.074624e-3
GO:0071422 succinate transmembrane transport 3.074624e-3
GO:0007144 female meiosis I 3.074624e-3
GO:0060580 ventral spinal cord interneuron fate determination 3.113505e-3
GO:0070535 histone H2A K63-linked ubiquitination 3.113505e-3
GO:0030150 protein import into mitochondrial matrix 3.113505e-3
GO:0018125 peptidyl-cysteine methylation 3.113505e-3
GO:0003327 type B pancreatic cell fate commitment 3.113505e-3
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 3.149268e-3
GO:0071281 cellular response to iron ion 3.270768e-3
GO:0070537 histone H2A K63-linked deubiquitination 3.270768e-3
GO:0060421 positive regulation of heart growth 3.345755e-3
GO:0042026 protein refolding 3.487283e-3
GO:0046881 positive regulation of follicle-stimulating hormone secretion 3.728470e-3
GO:0003329 pancreatic PP cell fate commitment 3.728470e-3
GO:0003326 pancreatic A cell fate commitment 3.728470e-3
GO:0007266 Rho protein signal transduction 3.753165e-3
GO:0030913 paranodal junction assembly 3.808037e-3
GO:0000910 cytokinesis 3.877210e-3
GO:0006323 DNA packaging 3.968027e-3
GO:0007354 zygotic determination of anterior/posterior axis, embryo 4.018348e-3
GO:0090234 regulation of kinetochore assembly 4.130643e-3
GO:0090169 regulation of spindle assembly 4.130643e-3
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 4.185640e-3
GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process 4.185640e-3
GO:0042840 D-glucuronate catabolic process 4.237711e-3
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.328334e-3
GO:0015827 tryptophan transport 4.332343e-3
GO:0006177 GMP biosynthetic process 4.332343e-3
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.379504e-3
GO:0035522 monoubiquitinated histone H2A deubiquitination 4.379504e-3
GO:0043048 dolichyl monophosphate biosynthetic process 4.379504e-3
GO:0035356 cellular triglyceride homeostasis 4.379504e-3
GO:0032329 serine transport 4.384142e-3
GO:0000077 DNA damage checkpoint 4.424673e-3
GO:0009147 pyrimidine nucleoside triphosphate metabolic process 4.600771e-3
GO:0022614 membrane to membrane docking 4.648010e-3
GO:0006906 vesicle fusion 4.677138e-3
GO:0090403 oxidative stress-induced premature senescence 4.762457e-3
GO:0022613 ribonucleoprotein complex biogenesis 4.953441e-3
GO:0034111 negative regulation of homotypic cell-cell adhesion 5.363214e-3
GO:0009299 mRNA transcription 5.403228e-3
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 5.403228e-3
GO:0051303 establishment of chromosome localization 5.557742e-3
GO:0044319 wound healing, spreading of cells 5.557742e-3
GO:0006013 mannose metabolic process 5.557742e-3
GO:2000015 regulation of determination of dorsal identity 5.608157e-3
GO:0007034 vacuolar transport 5.700305e-3
GO:0046931 pore complex assembly 5.781048e-3
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 5.810235e-3
GO:0010107 potassium ion import 5.842736e-3
GO:0006837 serotonin transport 5.931832e-3
GO:0015677 copper ion import 5.942506e-3
GO:0060003 copper ion export 5.942506e-3
GO:0002541 activation of plasma proteins involved in acute inflammatory response 5.942506e-3
GO:0005980 glycogen catabolic process 6.052670e-3
GO:0070389 chaperone cofactor-dependent protein refolding 6.115556e-3
GO:0006999 nuclear pore organization 6.115556e-3
GO:2000036 regulation of stem cell maintenance 6.276951e-3
GO:0009083 branched chain family amino acid catabolic process 6.402379e-3
GO:0000080 G1 phase of mitotic cell cycle 6.590289e-3
GO:0002740 negative regulation of cytokine secretion involved in immune response 6.606238e-3
GO:0031398 positive regulation of protein ubiquitination 6.715684e-3
GO:0001824 blastocyst development 6.817883e-3
GO:0031570 DNA integrity checkpoint 6.875585e-3
GO:0001832 blastocyst growth 6.986770e-3
GO:0070935 3'-UTR-mediated mRNA stabilization 7.035478e-3
GO:0035511 oxidative DNA demethylation 7.172731e-3
GO:0016973 poly(A)+ mRNA export from nucleus 7.172731e-3
GO:0060554 induction of necroptosis of activated-T cells 7.218663e-3
GO:2000016 negative regulation of determination of dorsal identity 7.218663e-3
GO:0048203 vesicle targeting, trans-Golgi to endosome 7.218663e-3
GO:0006178 guanine salvage 7.218663e-3
GO:0046038 GMP catabolic process 7.218663e-3
GO:0032263 GMP salvage 7.218663e-3
GO:0032264 IMP salvage 7.218663e-3
GO:0032099 negative regulation of appetite 7.251017e-3
GO:0008635 activation of caspase activity by cytochrome c 7.350597e-3
GO:0001820 serotonin secretion 7.373304e-3
GO:0070172 positive regulation of tooth mineralization 7.508288e-3
GO:0015931 nucleobase-containing compound transport 7.524279e-3
GO:0021997 neural plate axis specification 7.604513e-3
GO:0060272 embryonic skeletal joint morphogenesis 7.669700e-3
GO:0016226 iron-sulfur cluster assembly 7.734374e-3
GO:0035552 oxidative single-stranded DNA demethylation 7.737757e-3
GO:0060040 retinal bipolar neuron differentiation 7.737757e-3
GO:0001732 formation of translation initiation complex 7.737757e-3
GO:0032092 positive regulation of protein binding 7.782157e-3
GO:0042732 D-xylose metabolic process 7.798950e-3
GO:0071158 positive regulation of cell cycle arrest 7.968384e-3
GO:0060017 parathyroid gland development 8.084722e-3
GO:0006517 protein deglycosylation 8.125781e-3
GO:0034276 kynurenic acid biosynthetic process 8.125781e-3
GO:0034725 DNA replication-dependent nucleosome disassembly 8.125781e-3
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 8.125781e-3
GO:0003259 cardioblast anterior-lateral migration 8.125781e-3
GO:0060975 cardioblast migration to the midline involved in heart field formation 8.125781e-3
GO:0002159 desmosome assembly 8.125781e-3
GO:0003236 sinus venosus morphogenesis 8.125781e-3
GO:0002534 cytokine production involved in inflammatory response 8.125781e-3
GO:0000027 ribosomal large subunit assembly 8.125781e-3
GO:0003210 cardiac atrium formation 8.125781e-3
GO:0002561 basophil degranulation 8.125781e-3
GO:0043300 regulation of leukocyte degranulation 8.230430e-3
GO:0071882 activation of phospholipase C activity by adrenergic receptor signaling pathway 8.253177e-3
GO:0071881 inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway 8.253177e-3
GO:0003418 growth plate cartilage chondrocyte differentiation 8.253177e-3
GO:0070625 zymogen granule exocytosis 8.253177e-3
GO:0071843 cellular component biogenesis at cellular level 8.381710e-3
GO:0032924 activin receptor signaling pathway 8.466962e-3
GO:0090399 replicative senescence 8.540707e-3
GO:0030325 adrenal gland development 8.564121e-3
GO:0032096 negative regulation of response to food 8.572731e-3
GO:0032369 negative regulation of lipid transport 8.623483e-3
GO:0061025 membrane fusion 9.001382e-3
GO:0005997 xylulose metabolic process 9.087735e-3
GO:0000492 box C/D snoRNP assembly 9.087735e-3
GO:0009303 rRNA transcription 9.093788e-3
GO:0031954 positive regulation of protein autophosphorylation 9.152255e-3
GO:0051340 regulation of ligase activity 9.515406e-3
GO:0035136 forelimb morphogenesis 9.589081e-3
GO:0090342 regulation of cell aging 9.887149e-3
GO:0009081 branched chain family amino acid metabolic process 9.964208e-3
GO:0043103 hypoxanthine salvage 1.006648e-2
GO:0032261 purine nucleotide salvage 1.006648e-2
GO:0050935 iridophore differentiation 1.007761e-2
GO:0085020 protein K6-linked ubiquitination 1.007761e-2
GO:0048937 lateral line nerve glial cell development 1.007761e-2
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 1.007761e-2
GO:0033299 secretion of lysosomal enzymes 1.007761e-2
GO:0035425 autocrine signaling 1.007761e-2
GO:0051318 G1 phase 1.012626e-2
GO:0006610 ribosomal protein import into nucleus 1.038211e-2
GO:0060356 leucine import 1.042771e-2
GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway 1.042771e-2
GO:0060236 regulation of mitotic spindle organization 1.042771e-2
GO:0006364 rRNA processing 1.077132e-2
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 1.105993e-2
GO:0072422 signal transduction involved in DNA damage checkpoint 1.124716e-2
GO:0002268 follicular dendritic cell differentiation 1.132178e-2
GO:0072074 kidney mesenchyme development 1.134700e-2
GO:0034553 mitochondrial respiratory chain complex II assembly 1.156759e-2
GO:0046185 aldehyde catabolic process 1.156759e-2
GO:0034509 centromeric core chromatin assembly 1.156759e-2
GO:0003127 detection of nodal flow 1.156759e-2
GO:0031081 nuclear pore distribution 1.156759e-2
GO:0034080 CenH3-containing nucleosome assembly at centromere 1.156759e-2
GO:0003163 sinoatrial node development 1.162677e-2
GO:0072498 embryonic skeletal joint development 1.172578e-2
GO:2000020 positive regulation of male gonad development 1.179752e-2
GO:0007521 muscle cell fate determination 1.198790e-2
GO:0060039 pericardium development 1.220515e-2
GO:0072075 metanephric mesenchyme development 1.249579e-2
GO:0032488 Cdc42 protein signal transduction 1.274494e-2
GO:0006390 transcription from mitochondrial promoter 1.283915e-2
GO:0072268 pattern specification involved in metanephros development 1.292434e-2
GO:0070366 regulation of hepatocyte differentiation 1.292434e-2
GO:0032916 positive regulation of transforming growth factor beta3 production 1.292434e-2
GO:0046985 positive regulation of hemoglobin biosynthetic process 1.329691e-2
GO:0043973 histone H3-K4 acetylation 1.329691e-2
GO:0045415 negative regulation of interleukin-8 biosynthetic process 1.329691e-2
GO:0035269 protein O-linked mannosylation 1.329691e-2
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 1.329691e-2
GO:0032049 cardiolipin biosynthetic process 1.356619e-2
GO:2000383 regulation of ectoderm development 1.356619e-2
GO:0007172 signal complex assembly 1.356619e-2
GO:0051865 protein autoubiquitination 1.366715e-2
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 1.396680e-2
GO:0045347 negative regulation of MHC class II biosynthetic process 1.396981e-2
GO:0070243 regulation of thymocyte apoptosis 1.419658e-2
GO:0000726 non-recombinational repair 1.424173e-2
GO:0002730 regulation of dendritic cell cytokine production 1.429864e-2
GO:0042664 negative regulation of endodermal cell fate specification 1.429864e-2
GO:0048313 Golgi inheritance 1.429864e-2
GO:0014063 negative regulation of serotonin secretion 1.429864e-2
GO:0040038 polar body extrusion after meiotic divisions 1.536862e-2
GO:0045769 negative regulation of asymmetric cell division 1.536862e-2
GO:0042941 D-alanine transport 1.536862e-2
GO:0017187 peptidyl-glutamic acid carboxylation 1.536862e-2
GO:0007057 spindle assembly involved in female meiosis I 1.536862e-2
GO:0009443 pyridoxal 5'-phosphate salvage 1.536862e-2
GO:0016482 cytoplasmic transport 1.536862e-2
GO:0032446 protein modification by small protein conjugation 1.538294e-2
GO:0030259 lipid glycosylation 1.549042e-2
GO:0035115 embryonic forelimb morphogenesis 1.554410e-2
GO:0003218 cardiac left ventricle formation 1.559444e-2
GO:0002031 G-protein coupled receptor internalization 1.559444e-2
GO:0033700 phospholipid efflux 1.602148e-2
GO:0035865 cellular response to potassium ion 1.651041e-2
GO:0035105 sterol regulatory element binding protein import into nucleus 1.651041e-2
GO:0045575 basophil activation 1.651041e-2
GO:0046814 virion attachment, binding of host cell surface coreceptor 1.651041e-2
GO:0060816 random inactivation of X chromosome 1.651041e-2
GO:0051790 short-chain fatty acid biosynthetic process 1.651041e-2
GO:0034651 cortisol biosynthetic process 1.651041e-2
GO:0034241 positive regulation of macrophage fusion 1.651041e-2
GO:0009786 regulation of asymmetric cell division 1.651041e-2
GO:0006256 UDP catabolic process 1.651041e-2
GO:0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction 1.651041e-2
GO:0019064 viral envelope fusion with host membrane 1.651041e-2
GO:0031468 nuclear envelope reassembly 1.651041e-2
GO:0030208 dermatan sulfate biosynthetic process 1.651041e-2
GO:0003430 growth plate cartilage chondrocyte growth 1.651041e-2
GO:0002262 myeloid cell homeostasis 1.678977e-2
GO:0042069 regulation of catecholamine metabolic process 1.679880e-2
GO:0021846 cell proliferation in forebrain 1.692265e-2
GO:0060921 sinoatrial node cell differentiation 1.696876e-2
GO:0048014 Tie receptor signaling pathway 1.696876e-2
GO:0071544 diphosphoinositol polyphosphate catabolic process 1.747856e-2
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 1.747856e-2
GO:0090045 positive regulation of deacetylase activity 1.747856e-2
GO:0043031 negative regulation of macrophage activation 1.747856e-2
GO:0006507 GPI anchor release 1.747856e-2
GO:0042789 mRNA transcription from RNA polymerase II promoter 1.747856e-2
GO:0016126 sterol biosynthetic process 1.751306e-2
GO:0007076 mitotic chromosome condensation 1.752288e-2
GO:0006366 transcription from RNA polymerase II promoter 1.765480e-2
GO:0046939 nucleotide phosphorylation 1.772414e-2
GO:0006868 glutamine transport 1.780220e-2
GO:0045739 positive regulation of DNA repair 1.809171e-2
GO:0090161 Golgi ribbon formation 1.832673e-2
GO:0051639 actin filament network formation 1.832673e-2
GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process 1.832673e-2
GO:0046882 negative regulation of follicle-stimulating hormone secretion 1.832673e-2
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1.832673e-2
GO:0006626 protein targeting to mitochondrion 1.848722e-2
GO:0060375 regulation of mast cell differentiation 1.872941e-2
GO:0001829 trophectodermal cell differentiation 1.875794e-2
GO:0060547 negative regulation of necrotic cell death 1.878025e-2
GO:0005981 regulation of glycogen catabolic process 1.881804e-2
GO:0035928 rRNA import into mitochondrion 1.886027e-2
GO:0018200 peptidyl-glutamic acid modification 1.910870e-2
GO:0007182 common-partner SMAD protein phosphorylation 1.910870e-2
GO:0033119 negative regulation of RNA splicing 1.917326e-2
GO:0002326 B cell lineage commitment 1.917326e-2
GO:0048284 organelle fusion 1.941243e-2
GO:0060347 heart trabecula formation 1.983979e-2
GO:0033364 mast cell secretory granule organization 2.017610e-2
GO:0016584 nucleosome positioning 2.017610e-2
GO:0010511 regulation of phosphatidylinositol biosynthetic process 2.038889e-2
GO:0017148 negative regulation of translation 2.088809e-2
GO:0035434 copper ion transmembrane transport 2.133550e-2
GO:0035510 DNA dealkylation 2.180105e-2
GO:0090209 negative regulation of triglyceride metabolic process 2.180105e-2
GO:0007566 embryo implantation 2.208247e-2
GO:0006944 cellular membrane fusion 2.223571e-2
GO:0010564 regulation of cell cycle process 2.238526e-2
GO:0033344 cholesterol efflux 2.248164e-2
GO:0034048 negative regulation of protein phosphatase type 2A activity 2.272614e-2
GO:0070093 negative regulation of glucagon secretion 2.272614e-2
GO:0032185 septin cytoskeleton organization 2.272614e-2
GO:0033566 gamma-tubulin complex localization 2.272614e-2
GO:0015680 intracellular copper ion transport 2.272614e-2
GO:0033631 cell-cell adhesion mediated by integrin 2.287214e-2
GO:0033025 regulation of mast cell apoptosis 2.287214e-2
GO:0007168 receptor guanylyl cyclase signaling pathway 2.287214e-2
GO:0061098 positive regulation of protein tyrosine kinase activity 2.355693e-2
GO:0043173 nucleotide salvage 2.359062e-2
GO:0072086 specification of loop of Henle identity 2.382188e-2
GO:0006511 ubiquitin-dependent protein catabolic process 2.385211e-2
GO:0043632 modification-dependent macromolecule catabolic process 2.430020e-2
GO:2000018 regulation of male gonad development 2.446271e-2
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 2.460111e-2
GO:0000089 mitotic metaphase 2.486333e-2
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 2.486333e-2
GO:0000729 DNA double-strand break processing 2.486333e-2
GO:0071711 basement membrane organization 2.492344e-2
GO:0009082 branched chain family amino acid biosynthetic process 2.492344e-2
GO:0051029 rRNA transport 2.492344e-2
GO:0033572 transferrin transport 2.516926e-2
GO:0001843 neural tube closure 2.518341e-2
GO:0009880 embryonic pattern specification 2.525752e-2
GO:0006282 regulation of DNA repair 2.536109e-2
GO:2000173 negative regulation of branching morphogenesis of a nerve 2.556431e-2
GO:0050655 dermatan sulfate proteoglycan metabolic process 2.556431e-2
GO:0016557 peroxisome membrane biogenesis 2.556431e-2
GO:0014842 regulation of satellite cell proliferation 2.556431e-2
GO:0045601 regulation of endothelial cell differentiation 2.559859e-2
GO:0060613 fat pad development 2.584726e-2
GO:0006303 double-strand break repair via nonhomologous end joining 2.584726e-2
GO:0016072 rRNA metabolic process 2.659413e-2
GO:0032910 regulation of transforming growth factor beta3 production 2.659528e-2
GO:0050685 positive regulation of mRNA processing 2.663598e-2
GO:0016567 protein ubiquitination 2.665799e-2
GO:0061146 Peyer's patch morphogenesis 2.676922e-2
GO:0051545 negative regulation of elastin biosynthetic process 2.676922e-2
GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development 2.676922e-2