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Novel motif:39

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name:motif39_CCAAGT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0032501 multicellular organismal process 1.913577e-15
GO:0002695 negative regulation of leukocyte activation 1.496243e-13
GO:0050896 response to stimulus 1.625313e-12
GO:0051250 negative regulation of lymphocyte activation 2.168784e-12
GO:0009653 anatomical structure morphogenesis 1.367254e-11
GO:0043252 sodium-independent organic anion transport 1.857695e-11
GO:0050866 negative regulation of cell activation 2.029004e-11
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 9.936072e-11
GO:0032502 developmental process 2.151458e-10
GO:2001021 negative regulation of response to DNA damage stimulus 3.596554e-10
GO:0051336 regulation of hydrolase activity 4.466500e-10
GO:0007275 multicellular organismal development 5.372223e-10
GO:0010035 response to inorganic substance 5.527772e-10
GO:0051249 regulation of lymphocyte activation 8.058078e-10
GO:0048731 system development 1.319211e-9
GO:0072358 cardiovascular system development 1.344199e-9
GO:0002683 negative regulation of immune system process 1.447292e-9
GO:0014075 response to amine stimulus 1.664264e-9
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 1.740799e-9
GO:0042221 response to chemical stimulus 3.524697e-9
GO:0010038 response to metal ion 3.814447e-9
GO:0048856 anatomical structure development 3.866240e-9
GO:0031099 regeneration 5.201267e-9
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 5.752119e-9
GO:0001101 response to acid 5.757006e-9
GO:0060574 intestinal epithelial cell maturation 6.726882e-9
GO:0043200 response to amino acid stimulus 6.764348e-9
GO:0002694 regulation of leukocyte activation 9.143225e-9
GO:0007154 cell communication 1.009048e-8
GO:0019836 hemolysis by symbiont of host erythrocytes 1.099256e-8
GO:0019805 quinolinate biosynthetic process 1.142081e-8
GO:0051659 maintenance of mitochondrion location 1.169077e-8
GO:0043067 regulation of programmed cell death 1.210957e-8
GO:0042981 regulation of apoptosis 1.516821e-8
GO:0051716 cellular response to stimulus 1.543758e-8
GO:0019853 L-ascorbic acid biosynthetic process 1.578945e-8
GO:0002828 regulation of type 2 immune response 1.778865e-8
GO:0023052 signaling 1.933785e-8
GO:0043009 chordate embryonic development 1.937738e-8
GO:0006950 response to stress 1.980374e-8
GO:0051657 maintenance of organelle location 2.449003e-8
GO:0070541 response to platinum ion 2.565166e-8
GO:0050789 regulation of biological process 2.680545e-8
GO:0030241 skeletal muscle myosin thick filament assembly 2.710352e-8
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 2.717158e-8
GO:0048513 organ development 2.775003e-8
GO:0044419 interspecies interaction between organisms 3.688014e-8
GO:0010941 regulation of cell death 4.774124e-8
GO:0009792 embryo development ending in birth or egg hatching 5.846023e-8
GO:0009605 response to external stimulus 6.112058e-8
GO:0050790 regulation of catalytic activity 6.312216e-8
GO:0032689 negative regulation of interferon-gamma production 8.337044e-8
GO:0007165 signal transduction 8.584024e-8
GO:0022414 reproductive process 8.606054e-8
GO:0000003 reproduction 8.921270e-8
GO:0030261 chromosome condensation 9.523203e-8
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 1.021978e-7
GO:0032910 regulation of transforming growth factor beta3 production 1.089013e-7
GO:0045109 intermediate filament organization 1.139146e-7
GO:0046874 quinolinate metabolic process 1.240611e-7
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 1.302159e-7
GO:0006182 cGMP biosynthetic process 1.373893e-7
GO:0032703 negative regulation of interleukin-2 production 1.685801e-7
GO:0060548 negative regulation of cell death 2.056874e-7
GO:0034104 negative regulation of tissue remodeling 2.121322e-7
GO:0043316 cytotoxic T cell degranulation 2.156737e-7
GO:0050865 regulation of cell activation 2.253507e-7
GO:0070663 regulation of leukocyte proliferation 2.461361e-7
GO:0002830 positive regulation of type 2 immune response 2.521459e-7
GO:0046851 negative regulation of bone remodeling 2.953855e-7
GO:0050794 regulation of cellular process 3.147544e-7
GO:0045779 negative regulation of bone resorption 3.455077e-7
GO:0048583 regulation of response to stimulus 3.496732e-7
GO:0016032 viral reproduction 3.510015e-7
GO:0010269 response to selenium ion 3.546954e-7
GO:0002376 immune system process 3.763470e-7
GO:0046578 regulation of Ras protein signal transduction 4.260691e-7
GO:0002831 regulation of response to biotic stimulus 4.293698e-7
GO:0014866 skeletal myofibril assembly 4.687891e-7
GO:0006952 defense response 4.765460e-7
GO:0035051 cardiac cell differentiation 4.838931e-7
GO:0044238 primary metabolic process 4.956145e-7
GO:0048739 cardiac muscle fiber development 5.028188e-7
GO:0032916 positive regulation of transforming growth factor beta3 production 5.401919e-7
GO:0032731 positive regulation of interleukin-1 beta production 5.430934e-7
GO:0002682 regulation of immune system process 5.636824e-7
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 5.675432e-7
GO:0070664 negative regulation of leukocyte proliferation 5.699046e-7
GO:0065007 biological regulation 5.925495e-7
GO:0009888 tissue development 6.641345e-7
GO:0006936 muscle contraction 6.791969e-7
GO:0032732 positive regulation of interleukin-1 production 7.265787e-7
GO:0050863 regulation of T cell activation 7.609309e-7
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 8.878396e-7
GO:0048468 cell development 9.113136e-7
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 9.355606e-7
GO:0045187 regulation of circadian sleep/wake cycle, sleep 9.417546e-7
GO:0052548 regulation of endopeptidase activity 1.028442e-6
GO:0050955 thermoception 1.037715e-6
GO:0043154 negative regulation of caspase activity 1.048657e-6
GO:0010466 negative regulation of peptidase activity 1.051718e-6
GO:0001834 trophectodermal cell proliferation 1.277581e-6
GO:0012501 programmed cell death 1.354913e-6
GO:0050868 negative regulation of T cell activation 1.458015e-6
GO:0006935 chemotaxis 1.523029e-6
GO:0048869 cellular developmental process 1.619648e-6
GO:0042157 lipoprotein metabolic process 1.793171e-6
GO:0060118 vestibular receptor cell development 1.932865e-6
GO:0006807 nitrogen compound metabolic process 1.960257e-6
GO:0065009 regulation of molecular function 1.989624e-6
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 2.024389e-6
GO:0032855 positive regulation of Rac GTPase activity 2.038229e-6
GO:0043069 negative regulation of programmed cell death 2.038566e-6
GO:0048646 anatomical structure formation involved in morphogenesis 2.108658e-6
GO:0030154 cell differentiation 2.183183e-6
GO:0006955 immune response 2.216579e-6
GO:0046078 dUMP metabolic process 2.298331e-6
GO:0032318 regulation of Ras GTPase activity 2.463412e-6
GO:0034754 cellular hormone metabolic process 2.516590e-6
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 2.617631e-6
GO:0042127 regulation of cell proliferation 2.624317e-6
GO:0007059 chromosome segregation 2.706226e-6
GO:0007507 heart development 2.779403e-6
GO:2000116 regulation of cysteine-type endopeptidase activity 2.785112e-6
GO:0022410 circadian sleep/wake cycle process 2.786022e-6
GO:0052547 regulation of peptidase activity 2.828506e-6
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 2.847621e-6
GO:0019222 regulation of metabolic process 2.906686e-6
GO:0002478 antigen processing and presentation of exogenous peptide antigen 3.389182e-6
GO:0007623 circadian rhythm 3.392046e-6
GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 3.431712e-6
GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 3.431712e-6
GO:0001501 skeletal system development 3.448735e-6
GO:0061043 regulation of vascular wound healing 3.535207e-6
GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis 3.808125e-6
GO:0042752 regulation of circadian rhythm 3.889180e-6
GO:0009887 organ morphogenesis 4.461483e-6
GO:0000279 M phase 4.499797e-6
GO:0055013 cardiac muscle cell development 4.779940e-6
GO:0006139 nucleobase-containing compound metabolic process 4.795931e-6
GO:0051345 positive regulation of hydrolase activity 4.945175e-6
GO:0001657 ureteric bud development 4.952897e-6
GO:0032989 cellular component morphogenesis 5.029142e-6
GO:0009074 aromatic amino acid family catabolic process 5.178383e-6
GO:0043094 cellular metabolic compound salvage 5.208954e-6
GO:0009611 response to wounding 5.331618e-6
GO:0002832 negative regulation of response to biotic stimulus 5.489479e-6
GO:0055003 cardiac myofibril assembly 5.840850e-6
GO:0051085 chaperone mediated protein folding requiring cofactor 5.851027e-6
GO:0043066 negative regulation of apoptosis 6.090957e-6
GO:0042940 D-amino acid transport 6.134246e-6
GO:0007584 response to nutrient 6.365632e-6
GO:0032320 positive regulation of Ras GTPase activity 6.489800e-6
GO:0007049 cell cycle 6.577235e-6
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 6.671320e-6
GO:0019088 immortalization of host cell by virus 6.987186e-6
GO:0006231 dTMP biosynthetic process 6.987186e-6
GO:0055007 cardiac muscle cell differentiation 7.083668e-6
GO:0002697 regulation of immune effector process 7.124977e-6
GO:0051346 negative regulation of hydrolase activity 7.279260e-6
GO:0006820 anion transport 7.291911e-6
GO:0019363 pyridine nucleotide biosynthetic process 7.617003e-6
GO:0042745 circadian sleep/wake cycle 7.699374e-6
GO:0006725 cellular aromatic compound metabolic process 7.704690e-6
GO:0010811 positive regulation of cell-substrate adhesion 8.404798e-6
GO:0006915 apoptosis 8.481292e-6
GO:0048514 blood vessel morphogenesis 9.308834e-6
GO:0008624 induction of apoptosis by extracellular signals 9.404948e-6
GO:0050688 regulation of defense response to virus 9.589764e-6
GO:0002251 organ or tissue specific immune response 9.733848e-6
GO:0034641 cellular nitrogen compound metabolic process 9.902638e-6
GO:0001667 ameboidal cell migration 1.021876e-5
GO:0048512 circadian behavior 1.061340e-5
GO:0010043 response to zinc ion 1.115783e-5
GO:0090291 negative regulation of osteoclast proliferation 1.158257e-5
GO:2000347 positive regulation of hepatocyte proliferation 1.158257e-5
GO:2000349 negative regulation of CD40 signaling pathway 1.158257e-5
GO:0072573 tolerance induction to lipopolysaccharide 1.158257e-5
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 1.158257e-5
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.158257e-5
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.158257e-5
GO:0048518 positive regulation of biological process 1.228789e-5
GO:0048769 sarcomerogenesis 1.248283e-5
GO:0051056 regulation of small GTPase mediated signal transduction 1.271669e-5
GO:0031397 negative regulation of protein ubiquitination 1.371831e-5
GO:0002069 columnar/cuboidal epithelial cell maturation 1.384049e-5
GO:0006508 proteolysis 1.388029e-5
GO:0031100 organ regeneration 1.421404e-5
GO:0060252 positive regulation of glial cell proliferation 1.427641e-5
GO:0007005 mitochondrion organization 1.436519e-5
GO:0035691 macrophage migration inhibitory factor signaling pathway 1.482468e-5
GO:0051701 interaction with host 1.544014e-5
GO:0008219 cell death 1.584614e-5
GO:0006569 tryptophan catabolic process 1.591059e-5
GO:0060126 somatotropin secreting cell differentiation 1.618062e-5
GO:0007093 mitotic cell cycle checkpoint 1.635228e-5
GO:0033273 response to vitamin 1.715903e-5
GO:0046635 positive regulation of alpha-beta T cell activation 1.720548e-5
GO:0035270 endocrine system development 1.723365e-5
GO:0016265 death 1.778633e-5
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade 1.782938e-5
GO:0006082 organic acid metabolic process 1.789314e-5
GO:0030239 myofibril assembly 1.808898e-5
GO:0000302 response to reactive oxygen species 1.852832e-5
GO:0043547 positive regulation of GTPase activity 1.908413e-5
GO:0007051 spindle organization 1.941160e-5
GO:0010628 positive regulation of gene expression 2.026547e-5
GO:0046850 regulation of bone remodeling 2.120484e-5
GO:0006568 tryptophan metabolic process 2.123071e-5
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 2.141092e-5
GO:0046634 regulation of alpha-beta T cell activation 2.152231e-5
GO:0008347 glial cell migration 2.261437e-5
GO:0050869 negative regulation of B cell activation 2.537617e-5
GO:0080090 regulation of primary metabolic process 2.548519e-5
GO:0010604 positive regulation of macromolecule metabolic process 2.602623e-5
GO:0010625 positive regulation of Schwann cell proliferation 2.603514e-5
GO:0032944 regulation of mononuclear cell proliferation 2.640269e-5
GO:0045124 regulation of bone resorption 2.680528e-5
GO:0032233 positive regulation of actin filament bundle assembly 2.755408e-5
GO:0045590 negative regulation of regulatory T cell differentiation 2.838442e-5
GO:0009162 deoxyribonucleoside monophosphate metabolic process 2.841633e-5
GO:0031032 actomyosin structure organization 2.897545e-5
GO:0048522 positive regulation of cellular process 2.955868e-5
GO:0014032 neural crest cell development 3.067928e-5
GO:0061008 hepaticobiliary system development 3.111825e-5
GO:0048729 tissue morphogenesis 3.158792e-5
GO:0042753 positive regulation of circadian rhythm 3.191369e-5
GO:0061298 retina vasculature development in camera-type eye 3.198242e-5
GO:0051704 multi-organism process 3.207856e-5
GO:0051004 regulation of lipoprotein lipase activity 3.241495e-5
GO:0019439 aromatic compound catabolic process 3.242109e-5
GO:0019752 carboxylic acid metabolic process 3.267056e-5
GO:0050670 regulation of lymphocyte proliferation 3.378244e-5
GO:0022415 viral reproductive process 3.434268e-5
GO:0008207 C21-steroid hormone metabolic process 3.466069e-5
GO:0070779 D-aspartate import 3.531412e-5
GO:0043031 negative regulation of macrophage activation 3.638160e-5
GO:0001701 in utero embryonic development 3.728906e-5
GO:0060322 head development 3.894808e-5
GO:0001756 somitogenesis 3.947057e-5
GO:0010761 fibroblast migration 3.979776e-5
GO:0040011 locomotion 3.986821e-5
GO:0002385 mucosal immune response 4.444057e-5
GO:0045630 positive regulation of T-helper 2 cell differentiation 4.462155e-5
GO:0048519 negative regulation of biological process 4.479953e-5
GO:0008283 cell proliferation 4.505547e-5
GO:0065008 regulation of biological quality 4.564476e-5
GO:0060351 cartilage development involved in endochondral bone morphogenesis 4.583005e-5
GO:0061053 somite development 4.624917e-5
GO:0001836 release of cytochrome c from mitochondria 4.647206e-5
GO:0050864 regulation of B cell activation 4.687507e-5
GO:0015742 alpha-ketoglutarate transport 4.711592e-5
GO:0010243 response to organic nitrogen 4.728217e-5
GO:0045621 positive regulation of lymphocyte differentiation 4.756370e-5
GO:0070670 response to interleukin-4 4.774099e-5
GO:0035023 regulation of Rho protein signal transduction 4.849371e-5
GO:0034135 regulation of toll-like receptor 2 signaling pathway 4.910933e-5
GO:0060323 head morphogenesis 5.039042e-5
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 5.219001e-5
GO:0033153 T cell receptor V(D)J recombination 5.258389e-5
GO:0001889 liver development 5.346571e-5
GO:0051045 negative regulation of membrane protein ectodomain proteolysis 5.389875e-5
GO:0010810 regulation of cell-substrate adhesion 5.416888e-5
GO:0007276 gamete generation 5.426388e-5
GO:0001954 positive regulation of cell-matrix adhesion 5.439500e-5
GO:0018874 benzoate metabolic process 5.469718e-5
GO:0040007 growth 5.479360e-5
GO:0048771 tissue remodeling 5.515745e-5
GO:0048644 muscle organ morphogenesis 5.548756e-5
GO:0044403 symbiosis, encompassing mutualism through parasitism 5.598222e-5
GO:0031570 DNA integrity checkpoint 5.598446e-5
GO:2000348 regulation of CD40 signaling pathway 5.606997e-5
GO:0010661 positive regulation of muscle cell apoptosis 5.606997e-5
GO:0042246 tissue regeneration 5.728436e-5
GO:0035435 phosphate ion transmembrane transport 5.906137e-5
GO:0043627 response to estrogen stimulus 5.933074e-5
GO:0048598 embryonic morphogenesis 6.035631e-5
GO:0016485 protein processing 6.154740e-5
GO:0003006 developmental process involved in reproduction 6.202057e-5
GO:0001957 intramembranous ossification 6.341217e-5
GO:0045581 negative regulation of T cell differentiation 6.396006e-5
GO:0009966 regulation of signal transduction 6.557582e-5
GO:0055086 nucleobase-containing small molecule metabolic process 6.598841e-5
GO:2000602 regulation of interphase of mitotic cell cycle 6.733303e-5
GO:0000077 DNA damage checkpoint 6.757293e-5
GO:0007585 respiratory gaseous exchange 6.763516e-5
GO:0048538 thymus development 6.907792e-5
GO:0009435 NAD biosynthetic process 7.026414e-5
GO:0042180 cellular ketone metabolic process 7.039490e-5
GO:0044249 cellular biosynthetic process 7.078466e-5
GO:0045103 intermediate filament-based process 7.094049e-5
GO:0043615 astrocyte cell migration 7.123297e-5
GO:0019884 antigen processing and presentation of exogenous antigen 7.254081e-5
GO:0001658 branching involved in ureteric bud morphogenesis 7.334806e-5
GO:0048539 bone marrow development 7.385590e-5
GO:0071780 mitotic cell cycle G2/M transition checkpoint 7.669767e-5
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway 7.785481e-5
GO:0014015 positive regulation of gliogenesis 7.822451e-5
GO:0006954 inflammatory response 7.941835e-5
GO:0018009 N-terminal peptidyl-L-cysteine N-palmitoylation 8.033092e-5
GO:0001525 angiogenesis 8.097688e-5
GO:0031016 pancreas development 8.265964e-5
GO:0015711 organic anion transport 8.336739e-5
GO:0003012 muscle system process 8.356092e-5
GO:0061325 cell proliferation involved in outflow tract morphogenesis 8.412224e-5
GO:0060127 prolactin secreting cell differentiation 8.412224e-5
GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis 8.412224e-5
GO:0009893 positive regulation of metabolic process 8.466376e-5
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 8.643356e-5
GO:0072224 metanephric glomerulus development 8.683236e-5
GO:0030237 female sex determination 8.720787e-5
GO:0043087 regulation of GTPase activity 8.785138e-5
GO:0060290 transdifferentiation 8.792819e-5
GO:0032652 regulation of interleukin-1 production 8.864838e-5
GO:0030240 skeletal muscle thin filament assembly 8.962975e-5
GO:0007168 receptor guanylyl cyclase signaling pathway 8.992451e-5
GO:0009124 nucleoside monophosphate biosynthetic process 9.020378e-5
GO:0060070 canonical Wnt receptor signaling pathway 9.352371e-5
GO:0032856 activation of Ras GTPase activity 9.469397e-5
GO:0042445 hormone metabolic process 9.719741e-5
GO:0032651 regulation of interleukin-1 beta production 9.785047e-5
GO:0001568 blood vessel development 9.809179e-5
GO:0045104 intermediate filament cytoskeleton organization 9.855523e-5
GO:0042542 response to hydrogen peroxide 1.000854e-4
GO:0010171 body morphogenesis 1.024919e-4
GO:0000087 M phase of mitotic cell cycle 1.026036e-4
GO:0007067 mitosis 1.030311e-4
GO:0022402 cell cycle process 1.031242e-4
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1.047213e-4
GO:0007622 rhythmic behavior 1.060391e-4
GO:0015910 peroxisomal long-chain fatty acid import 1.065439e-4
GO:0006493 protein O-linked glycosylation 1.069961e-4
GO:0050795 regulation of behavior 1.077807e-4
GO:0035239 tube morphogenesis 1.095261e-4
GO:0060562 epithelial tube morphogenesis 1.097616e-4
GO:0055008 cardiac muscle tissue morphogenesis 1.134673e-4
GO:0060324 face development 1.144761e-4
GO:0008152 metabolic process 1.169130e-4
GO:0061307 cardiac neural crest cell differentiation involved in heart development 1.174690e-4
GO:0046512 sphingosine biosynthetic process 1.185385e-4
GO:0009855 determination of bilateral symmetry 1.189174e-4
GO:0042703 menstruation 1.190754e-4
GO:0019101 female somatic sex determination 1.190754e-4
GO:0051239 regulation of multicellular organismal process 1.196935e-4
GO:0048285 organelle fission 1.204245e-4
GO:0006434 seryl-tRNA aminoacylation 1.231872e-4
GO:0048738 cardiac muscle tissue development 1.297054e-4
GO:0009799 specification of symmetry 1.303492e-4
GO:0060700 regulation of ribonuclease activity 1.307589e-4
GO:0032321 positive regulation of Rho GTPase activity 1.329136e-4
GO:0046638 positive regulation of alpha-beta T cell differentiation 1.397530e-4
GO:0031667 response to nutrient levels 1.412338e-4
GO:0006435 threonyl-tRNA aminoacylation 1.423738e-4
GO:0016055 Wnt receptor signaling pathway 1.450141e-4
GO:0045582 positive regulation of T cell differentiation 1.474429e-4
GO:0043900 regulation of multi-organism process 1.480201e-4
GO:0046483 heterocycle metabolic process 1.504471e-4
GO:0000819 sister chromatid segregation 1.525007e-4
GO:0031575 mitotic cell cycle G1/S transition checkpoint 1.530946e-4
GO:0051496 positive regulation of stress fiber assembly 1.575769e-4
GO:0002074 extraocular skeletal muscle development 1.600029e-4
GO:0045589 regulation of regulatory T cell differentiation 1.608000e-4
GO:0006586 indolalkylamine metabolic process 1.622570e-4
GO:0015810 aspartate transport 1.656507e-4
GO:0032101 regulation of response to external stimulus 1.676160e-4
GO:0032845 negative regulation of homeostatic process 1.690683e-4
GO:0072404 signal transduction involved in G1/S transition checkpoint 1.697481e-4
GO:0060255 regulation of macromolecule metabolic process 1.699615e-4
GO:0072422 signal transduction involved in DNA damage checkpoint 1.761667e-4
GO:0044281 small molecule metabolic process 1.890701e-4
GO:0033962 cytoplasmic mRNA processing body assembly 1.896283e-4
GO:0010666 positive regulation of cardiac muscle cell apoptosis 1.917728e-4
GO:0010927 cellular component assembly involved in morphogenesis 2.016070e-4
GO:0070098 chemokine-mediated signaling pathway 2.033831e-4
GO:0006427 histidyl-tRNA aminoacylation 2.053055e-4
GO:0060973 cell migration involved in heart development 2.064086e-4
GO:0045329 carnitine biosynthetic process 2.158606e-4
GO:0043420 anthranilate metabolic process 2.179764e-4
GO:0034516 response to vitamin B6 2.179764e-4
GO:0060442 branching involved in prostate gland morphogenesis 2.205486e-4
GO:0019953 sexual reproduction 2.207265e-4
GO:0071779 G1/S transition checkpoint 2.222362e-4
GO:0019442 tryptophan catabolic process to acetyl-CoA 2.276984e-4
GO:0023019 signal transduction involved in regulation of gene expression 2.328725e-4
GO:0050870 positive regulation of T cell activation 2.447614e-4
GO:0045786 negative regulation of cell cycle 2.488650e-4
GO:0071732 cellular response to nitric oxide 2.498591e-4
GO:0032663 regulation of interleukin-2 production 2.582300e-4
GO:0060675 ureteric bud morphogenesis 2.597802e-4
GO:0033693 neurofilament bundle assembly 2.619106e-4
GO:0019359 nicotinamide nucleotide biosynthetic process 2.624596e-4
GO:0006414 translational elongation 2.630484e-4
GO:0009058 biosynthetic process 2.642446e-4
GO:0033124 regulation of GTP catabolic process 2.656421e-4
GO:0048545 response to steroid hormone stimulus 2.688347e-4
GO:0031323 regulation of cellular metabolic process 2.734808e-4
GO:0072395 signal transduction involved in cell cycle checkpoint 2.790819e-4
GO:0071712 ER-associated misfolded protein catabolic process 2.816654e-4
GO:0055001 muscle cell development 2.889773e-4
GO:0050672 negative regulation of lymphocyte proliferation 2.902565e-4
GO:0043170 macromolecule metabolic process 2.905494e-4
GO:0060764 cell-cell signaling involved in mammary gland development 3.070371e-4
GO:0044003 modification by symbiont of host morphology or physiology 3.071366e-4
GO:0003417 growth plate cartilage development 3.098891e-4
GO:0050747 positive regulation of lipoprotein metabolic process 3.117593e-4
GO:0032700 negative regulation of interleukin-17 production 3.190335e-4
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 3.201682e-4
GO:0048609 multicellular organismal reproductive process 3.225006e-4
GO:0001503 ossification 3.230567e-4
GO:0010033 response to organic substance 3.361492e-4
GO:0016338 calcium-independent cell-cell adhesion 3.363655e-4
GO:0060415 muscle tissue morphogenesis 3.376397e-4
GO:0006642 triglyceride mobilization 3.498977e-4
GO:0051246 regulation of protein metabolic process 3.501662e-4
GO:0035470 positive regulation of vascular wound healing 3.519485e-4
GO:0032754 positive regulation of interleukin-5 production 3.619528e-4
GO:0060325 face morphogenesis 3.663182e-4
GO:0070849 response to epidermal growth factor stimulus 3.667104e-4
GO:0045620 negative regulation of lymphocyte differentiation 3.676930e-4
GO:0050678 regulation of epithelial cell proliferation 3.728889e-4
GO:0071353 cellular response to interleukin-4 3.773799e-4
GO:0045785 positive regulation of cell adhesion 3.800685e-4
GO:0032495 response to muramyl dipeptide 3.834948e-4
GO:0048608 reproductive structure development 3.847161e-4
GO:0016337 cell-cell adhesion 3.863471e-4
GO:0061138 morphogenesis of a branching epithelium 3.869082e-4
GO:0007283 spermatogenesis 3.870398e-4
GO:0001944 vasculature development 3.872989e-4
GO:0051234 establishment of localization 3.910071e-4
GO:0034654 nucleobase-containing compound biosynthetic process 3.937165e-4
GO:0070682 proteasome regulatory particle assembly 3.938152e-4
GO:0032720 negative regulation of tumor necrosis factor production 3.954553e-4
GO:2000345 regulation of hepatocyte proliferation 3.991357e-4
GO:0030048 actin filament-based movement 4.049042e-4
GO:0048523 negative regulation of cellular process 4.070930e-4
GO:0009112 nucleobase metabolic process 4.073167e-4
GO:0046395 carboxylic acid catabolic process 4.213600e-4
GO:0050951 sensory perception of temperature stimulus 4.217777e-4
GO:0002426 immunoglobulin production in mucosal tissue 4.217777e-4
GO:0018993 somatic sex determination 4.255410e-4
GO:0001763 morphogenesis of a branching structure 4.397354e-4
GO:0048754 branching morphogenesis of a tube 4.397403e-4
GO:0044237 cellular metabolic process 4.449170e-4
GO:0002009 morphogenesis of an epithelium 4.508696e-4
GO:0008284 positive regulation of cell proliferation 4.549957e-4
GO:0006520 cellular amino acid metabolic process 4.600559e-4
GO:0055093 response to hyperoxia 4.616570e-4
GO:0006627 protein processing involved in protein targeting to mitochondrion 4.655220e-4
GO:0071294 cellular response to zinc ion 4.655220e-4
GO:0051251 positive regulation of lymphocyte activation 4.678698e-4
GO:0050727 regulation of inflammatory response 4.691411e-4
GO:0001553 luteinization 4.727666e-4
GO:0001817 regulation of cytokine production 4.744543e-4
GO:0070372 regulation of ERK1 and ERK2 cascade 4.775376e-4
GO:0007411 axon guidance 4.788640e-4
GO:0001922 B-1 B cell homeostasis 4.799967e-4
GO:0018130 heterocycle biosynthetic process 4.814148e-4
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway 4.822923e-4
GO:0046686 response to cadmium ion 4.851802e-4
GO:0021516 dorsal spinal cord development 4.870957e-4
GO:0043403 skeletal muscle tissue regeneration 4.882283e-4
GO:0050690 regulation of defense response to virus by virus 4.907404e-4
GO:0018199 peptidyl-glutamine modification 4.913730e-4
GO:0030916 otic vesicle formation 4.929306e-4
GO:0046394 carboxylic acid biosynthetic process 5.022086e-4
GO:0070374 positive regulation of ERK1 and ERK2 cascade 5.056692e-4
GO:0006670 sphingosine metabolic process 5.103710e-4
GO:0048546 digestive tract morphogenesis 5.151554e-4
GO:0070741 response to interleukin-6 5.184454e-4
GO:0009991 response to extracellular stimulus 5.205643e-4
GO:0030049 muscle filament sliding 5.221475e-4
GO:0042159 lipoprotein catabolic process 5.476354e-4
GO:0014038 regulation of Schwann cell differentiation 5.546525e-4
GO:0009123 nucleoside monophosphate metabolic process 5.572364e-4
GO:0030168 platelet activation 5.629446e-4
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 5.710843e-4
GO:0008637 apoptotic mitochondrial changes 5.767937e-4
GO:0002906 negative regulation of mature B cell apoptosis 5.779766e-4
GO:0021915 neural tube development 5.832257e-4
GO:0030198 extracellular matrix organization 5.834681e-4
GO:0021999 neural plate anterior/posterior regionalization 5.862815e-4
GO:0045619 regulation of lymphocyte differentiation 5.875855e-4
GO:0045071 negative regulation of viral genome replication 6.052386e-4
GO:0060907 positive regulation of macrophage cytokine production 6.107423e-4
GO:0002246 wound healing involved in inflammatory response 6.115251e-4
GO:0001934 positive regulation of protein phosphorylation 6.178153e-4
GO:0048589 developmental growth 6.335159e-4
GO:0006941 striated muscle contraction 6.336227e-4
GO:0002520 immune system development 6.383076e-4
GO:0051094 positive regulation of developmental process 6.403901e-4
GO:0030903 notochord development 6.459291e-4
GO:0022614 membrane to membrane docking 6.518093e-4
GO:0042448 progesterone metabolic process 6.520080e-4
GO:0033121 regulation of purine nucleotide catabolic process 6.523695e-4
GO:0060346 bone trabecula formation 6.548520e-4
GO:0042364 water-soluble vitamin biosynthetic process 6.551934e-4
GO:0048511 rhythmic process 6.596163e-4
GO:0009165 nucleotide biosynthetic process 6.725824e-4
GO:0061061 muscle structure development 6.734346e-4
GO:0019674 NAD metabolic process 6.834474e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0048240 sperm capacitation 9.256051e-17
GO:0006952 defense response 3.221315e-15
GO:0042742 defense response to bacterium 9.358304e-12
GO:0045071 negative regulation of viral genome replication 1.048234e-11
GO:0048525 negative regulation of viral reproduction 1.508052e-11
GO:0008207 C21-steroid hormone metabolic process 1.811907e-11
GO:0045869 negative regulation of retroviral genome replication 3.152400e-11
GO:0006954 inflammatory response 5.660861e-11
GO:0006950 response to stress 1.404699e-10
GO:0055114 oxidation-reduction process 8.337727e-10
GO:0006629 lipid metabolic process 1.460008e-9
GO:0045091 regulation of retroviral genome replication 1.719718e-9
GO:0051704 multi-organism process 2.863028e-9
GO:0045947 negative regulation of translational initiation 2.946634e-9
GO:0050896 response to stimulus 3.344043e-9
GO:2000121 regulation of removal of superoxide radicals 3.509472e-9
GO:0009566 fertilization 3.965070e-9
GO:0042953 lipoprotein transport 4.122228e-9
GO:0060613 fat pad development 4.292101e-9
GO:0051707 response to other organism 7.502409e-9
GO:0034754 cellular hormone metabolic process 1.207230e-8
GO:0045834 positive regulation of lipid metabolic process 1.638213e-8
GO:0006436 tryptophanyl-tRNA aminoacylation 1.794987e-8
GO:0006704 glucocorticoid biosynthetic process 2.014183e-8
GO:0010883 regulation of lipid storage 2.271868e-8
GO:0022414 reproductive process 2.286646e-8
GO:0010155 regulation of proton transport 3.129407e-8
GO:0045006 DNA deamination 3.483656e-8
GO:0009617 response to bacterium 3.562307e-8
GO:0015911 plasma membrane long-chain fatty acid transport 3.914440e-8
GO:0006700 C21-steroid hormone biosynthetic process 4.004376e-8
GO:0050710 negative regulation of cytokine secretion 6.080076e-8
GO:0006810 transport 7.415077e-8
GO:0044255 cellular lipid metabolic process 7.560716e-8
GO:0008202 steroid metabolic process 7.805982e-8
GO:0045738 negative regulation of DNA repair 8.154250e-8
GO:0051023 regulation of immunoglobulin secretion 9.586326e-8
GO:0009607 response to biotic stimulus 1.024485e-7
GO:0003006 developmental process involved in reproduction 1.230373e-7
GO:0000003 reproduction 1.308338e-7
GO:0007276 gamete generation 1.464102e-7
GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining 1.876329e-7
GO:2001038 regulation of cellular response to drug 1.876329e-7
GO:2000685 positive regulation of cellular response to X-ray 1.876329e-7
GO:0035988 chondrocyte proliferation 1.876329e-7
GO:0031052 chromosome breakage 1.876329e-7
GO:0035978 histone H2A-S139 phosphorylation 1.876329e-7
GO:0003131 mesodermal-endodermal cell signaling 1.876329e-7
GO:0010743 regulation of macrophage derived foam cell differentiation 2.209874e-7
GO:0051234 establishment of localization 5.531319e-7
GO:0030325 adrenal gland development 5.655060e-7
GO:0045190 isotype switching 5.823103e-7
GO:0008211 glucocorticoid metabolic process 6.593929e-7
GO:0019433 triglyceride catabolic process 6.707538e-7
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 8.125745e-7
GO:0061041 regulation of wound healing 8.507477e-7
GO:0051179 localization 8.584210e-7
GO:0007512 adult heart development 9.278535e-7
GO:0006641 triglyceride metabolic process 9.881875e-7
GO:0048515 spermatid differentiation 1.192587e-6
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 1.230751e-6
GO:0015860 purine nucleoside transport 1.232841e-6
GO:0090322 regulation of superoxide metabolic process 1.235157e-6
GO:0080134 regulation of response to stress 1.719414e-6
GO:0051883 killing of cells in other organism involved in symbiotic interaction 2.056716e-6
GO:0042448 progesterone metabolic process 2.062857e-6
GO:0002366 leukocyte activation involved in immune response 2.133247e-6
GO:0072527 pyrimidine-containing compound metabolic process 2.254409e-6
GO:0019836 hemolysis by symbiont of host erythrocytes 2.285154e-6
GO:0046689 response to mercury ion 2.369437e-6
GO:0045137 development of primary sexual characteristics 2.423061e-6
GO:0031640 killing of cells of other organism 2.646187e-6
GO:0019953 sexual reproduction 3.020601e-6
GO:0031953 negative regulation of protein autophosphorylation 3.810992e-6
GO:0072091 regulation of stem cell proliferation 3.941190e-6
GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 4.049357e-6
GO:2000648 positive regulation of stem cell proliferation 4.070771e-6
GO:0045348 positive regulation of MHC class II biosynthetic process 4.183471e-6
GO:0006091 generation of precursor metabolites and energy 4.677549e-6
GO:0015980 energy derivation by oxidation of organic compounds 4.961688e-6
GO:0051240 positive regulation of multicellular organismal process 5.431307e-6
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 5.517247e-6
GO:2000275 regulation of oxidative phosphorylation uncoupler activity 5.547801e-6
GO:0006642 triglyceride mobilization 5.878317e-6
GO:0051235 maintenance of location 5.970533e-6
GO:0050709 negative regulation of protein secretion 6.106622e-6
GO:0050873 brown fat cell differentiation 6.191973e-6
GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport 6.476937e-6
GO:0043901 negative regulation of multi-organism process 6.480902e-6
GO:0017148 negative regulation of translation 6.839147e-6
GO:0006310 DNA recombination 6.900717e-6
GO:0002449 lymphocyte mediated immunity 6.979026e-6
GO:0051657 maintenance of organelle location 6.980994e-6
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 7.249415e-6
GO:0051645 Golgi localization 7.312349e-6
GO:0051659 maintenance of mitochondrion location 7.383423e-6
GO:0071447 cellular response to hydroperoxide 7.392329e-6
GO:0048557 embryonic digestive tract morphogenesis 7.418973e-6
GO:0060100 positive regulation of phagocytosis, engulfment 7.960608e-6
GO:0031034 myosin filament assembly 8.296823e-6
GO:0046503 glycerolipid catabolic process 8.596976e-6
GO:0046464 acylglycerol catabolic process 8.702620e-6
GO:0032649 regulation of interferon-gamma production 9.083411e-6
GO:0048305 immunoglobulin secretion 9.512398e-6
GO:0045649 regulation of macrophage differentiation 9.612947e-6
GO:0071356 cellular response to tumor necrosis factor 9.631147e-6
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 1.003862e-5
GO:0007548 sex differentiation 1.013518e-5
GO:0010817 regulation of hormone levels 1.051762e-5
GO:0018904 organic ether metabolic process 1.119600e-5
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine 1.149747e-5
GO:0002312 B cell activation involved in immune response 1.167039e-5
GO:0030261 chromosome condensation 1.312445e-5
GO:0021548 pons development 1.441209e-5
GO:0043410 positive regulation of MAPKKK cascade 1.557151e-5
GO:0050820 positive regulation of coagulation 1.578638e-5
GO:0048584 positive regulation of response to stimulus 1.629859e-5
GO:0051239 regulation of multicellular organismal process 1.638181e-5
GO:0032656 regulation of interleukin-13 production 1.652963e-5
GO:2000465 regulation of glycogen (starch) synthase activity 1.682308e-5
GO:0030194 positive regulation of blood coagulation 1.747382e-5
GO:0045069 regulation of viral genome replication 1.807201e-5
GO:0007283 spermatogenesis 1.847662e-5
GO:0070541 response to platinum ion 1.849439e-5
GO:0044281 small molecule metabolic process 1.892137e-5
GO:2000677 regulation of transcription regulatory region DNA binding 1.904741e-5
GO:0046330 positive regulation of JNK cascade 1.967794e-5
GO:0048519 negative regulation of biological process 1.989228e-5
GO:0002676 regulation of chronic inflammatory response 1.993055e-5
GO:0007623 circadian rhythm 2.015398e-5
GO:0044403 symbiosis, encompassing mutualism through parasitism 2.018746e-5
GO:0010744 positive regulation of macrophage derived foam cell differentiation 2.034348e-5
GO:0045650 negative regulation of macrophage differentiation 2.079074e-5
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity 2.094201e-5
GO:0021754 facial nucleus development 2.094201e-5
GO:0001817 regulation of cytokine production 2.258386e-5
GO:0060008 Sertoli cell differentiation 2.342701e-5
GO:0007281 germ cell development 2.387741e-5
GO:0002686 negative regulation of leukocyte migration 2.388382e-5
GO:0048609 multicellular organismal reproductive process 2.391599e-5
GO:0045638 negative regulation of myeloid cell differentiation 2.416098e-5
GO:0045940 positive regulation of steroid metabolic process 2.460356e-5
GO:0072529 pyrimidine-containing compound catabolic process 2.472043e-5
GO:0006662 glycerol ether metabolic process 2.602704e-5
GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction 2.711262e-5
GO:0006446 regulation of translational initiation 2.814221e-5
GO:2000334 positive regulation of blood microparticle formation 2.987275e-5
GO:0032269 negative regulation of cellular protein metabolic process 3.084088e-5
GO:0008610 lipid biosynthetic process 3.104691e-5
GO:0019752 carboxylic acid metabolic process 3.262175e-5
GO:0009972 cytidine deamination 3.317172e-5
GO:0048512 circadian behavior 3.329524e-5
GO:0002544 chronic inflammatory response 3.571043e-5
GO:0016447 somatic recombination of immunoglobulin gene segments 3.612004e-5
GO:0001775 cell activation 3.718068e-5
GO:0019722 calcium-mediated signaling 3.850216e-5
GO:0043589 skin morphogenesis 3.854355e-5
GO:0044130 negative regulation of growth of symbiont in host 3.871469e-5
GO:0042753 positive regulation of circadian rhythm 3.922630e-5
GO:0010529 negative regulation of transposition 4.098014e-5
GO:0070383 DNA cytosine deamination 4.098014e-5
GO:0045988 negative regulation of striated muscle contraction 4.166458e-5
GO:0002682 regulation of immune system process 4.193400e-5
GO:0043900 regulation of multi-organism process 4.402207e-5
GO:0019216 regulation of lipid metabolic process 4.461359e-5
GO:0006639 acylglycerol metabolic process 4.533136e-5
GO:0042221 response to chemical stimulus 4.565035e-5
GO:0002440 production of molecular mediator of immune response 4.565661e-5
GO:0006930 substrate-dependent cell migration, cell extension 4.590518e-5
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.590518e-5
GO:0042180 cellular ketone metabolic process 4.654374e-5
GO:0050818 regulation of coagulation 4.679518e-5
GO:0008406 gonad development 4.799728e-5
GO:0065007 biological regulation 4.949234e-5
GO:0007286 spermatid development 4.993407e-5
GO:0051100 negative regulation of binding 5.099388e-5
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 5.267397e-5
GO:0031649 heat generation 5.458907e-5
GO:0030193 regulation of blood coagulation 5.508422e-5
GO:0045346 regulation of MHC class II biosynthetic process 5.666069e-5
GO:0002443 leukocyte mediated immunity 5.724751e-5
GO:2000467 positive regulation of glycogen (starch) synthase activity 5.803536e-5
GO:0019218 regulation of steroid metabolic process 5.907541e-5
GO:0019724 B cell mediated immunity 5.920796e-5
GO:0051716 cellular response to stimulus 6.026126e-5
GO:0034612 response to tumor necrosis factor 6.028603e-5
GO:0001818 negative regulation of cytokine production 6.333735e-5
GO:0043252 sodium-independent organic anion transport 6.388759e-5
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 6.452795e-5
GO:0002678 positive regulation of chronic inflammatory response 6.700750e-5
GO:0044242 cellular lipid catabolic process 6.743005e-5
GO:0014003 oligodendrocyte development 6.904915e-5
GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine 6.911801e-5
GO:0051970 negative regulation of transmission of nerve impulse 7.066485e-5
GO:0016064 immunoglobulin mediated immune response 7.391673e-5
GO:0006082 organic acid metabolic process 7.486870e-5
GO:0002874 regulation of chronic inflammatory response to antigenic stimulus 7.596105e-5
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7.716397e-5
GO:0043309 regulation of eosinophil degranulation 7.773855e-5
GO:0006909 phagocytosis 7.838665e-5
GO:0048545 response to steroid hormone stimulus 7.866824e-5
GO:0003096 renal sodium ion transport 8.430475e-5
GO:0032782 bile acid secretion 8.430475e-5
GO:0044419 interspecies interaction between organisms 8.526540e-5
GO:0016445 somatic diversification of immunoglobulins 8.715247e-5
GO:0010466 negative regulation of peptidase activity 8.824523e-5
GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure 9.248921e-5
GO:0048566 embryonic digestive tract development 9.725780e-5
GO:0051224 negative regulation of protein transport 9.875376e-5
GO:0030643 cellular phosphate ion homeostasis 1.041249e-4
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 1.053448e-4
GO:0002831 regulation of response to biotic stimulus 1.061384e-4
GO:0046325 negative regulation of glucose import 1.081352e-4
GO:0019915 lipid storage 1.100773e-4
GO:0034383 low-density lipoprotein particle clearance 1.136167e-4
GO:0032689 negative regulation of interferon-gamma production 1.136167e-4
GO:0042574 retinal metabolic process 1.139889e-4
GO:0050805 negative regulation of synaptic transmission 1.155698e-4
GO:0090402 oncogene-induced senescence 1.167864e-4
GO:2000774 positive regulation of cellular senescence 1.167864e-4
GO:0035986 senescence-associated heterochromatin focus formation 1.167864e-4
GO:0006955 immune response 1.178682e-4
GO:0032680 regulation of tumor necrosis factor production 1.188197e-4
GO:0010888 negative regulation of lipid storage 1.235303e-4
GO:0043277 apoptotic cell clearance 1.253282e-4
GO:0046546 development of primary male sexual characteristics 1.266370e-4
GO:0045333 cellular respiration 1.275629e-4
GO:0007622 rhythmic behavior 1.287847e-4
GO:0044341 sodium-dependent phosphate transport 1.304155e-4
GO:0050830 defense response to Gram-positive bacterium 1.310766e-4
GO:0042445 hormone metabolic process 1.324616e-4
GO:0009719 response to endogenous stimulus 1.332840e-4
GO:0031952 regulation of protein autophosphorylation 1.391937e-4
GO:0001985 negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 1.406325e-4
GO:0008584 male gonad development 1.418536e-4
GO:0051101 regulation of DNA binding 1.439326e-4
GO:2000772 regulation of cellular senescence 1.505670e-4
GO:0032655 regulation of interleukin-12 production 1.528829e-4
GO:0045321 leukocyte activation 1.557378e-4
GO:0032653 regulation of interleukin-10 production 1.581870e-4
GO:0071221 cellular response to bacterial lipopeptide 1.616473e-4
GO:0051248 negative regulation of protein metabolic process 1.642393e-4
GO:0006942 regulation of striated muscle contraction 1.642795e-4
GO:0007009 plasma membrane organization 1.661457e-4
GO:0032733 positive regulation of interleukin-10 production 1.678332e-4
GO:0060123 regulation of growth hormone secretion 1.688924e-4
GO:0031645 negative regulation of neurological system process 1.691841e-4
GO:0051241 negative regulation of multicellular organismal process 1.725644e-4
GO:0002377 immunoglobulin production 1.856779e-4
GO:0051640 organelle localization 1.862834e-4
GO:0030728 ovulation 1.883724e-4
GO:0008286 insulin receptor signaling pathway 1.899038e-4
GO:2000377 regulation of reactive oxygen species metabolic process 1.929755e-4
GO:0051651 maintenance of location in cell 1.932815e-4
GO:0051586 positive regulation of dopamine uptake 1.933734e-4
GO:2000279 negative regulation of DNA biosynthetic process 1.975378e-4
GO:0032735 positive regulation of interleukin-12 production 1.976302e-4
GO:0010885 regulation of cholesterol storage 1.979352e-4
GO:0006929 substrate-dependent cell migration 2.003171e-4
GO:0045444 fat cell differentiation 2.064946e-4
GO:0060341 regulation of cellular localization 2.071986e-4
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 2.147742e-4
GO:0001906 cell killing 2.171274e-4
GO:0010829 negative regulation of glucose transport 2.198343e-4
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 2.199526e-4
GO:0032642 regulation of chemokine production 2.217645e-4
GO:0010460 positive regulation of heart rate 2.240122e-4
GO:0002285 lymphocyte activation involved in immune response 2.254579e-4
GO:0048518 positive regulation of biological process 2.257953e-4
GO:0021678 third ventricle development 2.274691e-4
GO:0006418 tRNA aminoacylation for protein translation 2.279013e-4
GO:0009725 response to hormone stimulus 2.287179e-4
GO:0048743 positive regulation of skeletal muscle fiber development 2.296932e-4
GO:0006206 pyrimidine base metabolic process 2.351913e-4
GO:0043467 regulation of generation of precursor metabolites and energy 2.395051e-4
GO:0044330 canonical Wnt receptor signaling pathway involved in positive regulation of wound healing 2.468561e-4
GO:0044328 canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration 2.468561e-4
GO:0044329 canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion 2.468561e-4
GO:0015872 dopamine transport 2.490377e-4
GO:0045065 cytotoxic T cell differentiation 2.506765e-4
GO:2000353 positive regulation of endothelial cell apoptosis 2.521973e-4
GO:0009611 response to wounding 2.582686e-4
GO:0043392 negative regulation of DNA binding 2.617139e-4
GO:0050994 regulation of lipid catabolic process 2.645432e-4
GO:0010906 regulation of glucose metabolic process 2.666960e-4
GO:0002740 negative regulation of cytokine secretion involved in immune response 2.681555e-4
GO:0033993 response to lipid 2.723583e-4
GO:0042474 middle ear morphogenesis 2.750988e-4
GO:0070257 positive regulation of mucus secretion 2.776062e-4
GO:2000679 positive regulation of transcription regulatory region DNA binding 2.845250e-4
GO:2000779 regulation of double-strand break repair 2.905987e-4
GO:0070255 regulation of mucus secretion 2.991349e-4
GO:0006638 neutral lipid metabolic process 3.148263e-4
GO:0017126 nucleologenesis 3.195591e-4
GO:0034381 plasma lipoprotein particle clearance 3.225207e-4
GO:0031668 cellular response to extracellular stimulus 3.232285e-4
GO:0002762 negative regulation of myeloid leukocyte differentiation 3.305001e-4
GO:0050789 regulation of biological process 3.323981e-4
GO:0051181 cofactor transport 3.443864e-4
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 3.479157e-4
GO:0051583 dopamine uptake 3.479157e-4
GO:0051461 positive regulation of corticotropin secretion 3.479880e-4
GO:2000683 regulation of cellular response to X-ray 3.483875e-4
GO:0001983 baroreceptor response to increased systemic arterial blood pressure 3.483875e-4
GO:0006643 membrane lipid metabolic process 3.551417e-4
GO:0007605 sensory perception of sound 3.582495e-4
GO:0002526 acute inflammatory response 3.594518e-4
GO:0010884 positive regulation of lipid storage 3.656252e-4
GO:0010886 positive regulation of cholesterol storage 3.694158e-4
GO:0021682 nerve maturation 3.705797e-4
GO:0019482 beta-alanine metabolic process 3.705797e-4
GO:0002839 positive regulation of immune response to tumor cell 3.707239e-4
GO:0010033 response to organic substance 3.752610e-4
GO:0061037 negative regulation of cartilage development 3.957076e-4
GO:0060324 face development 3.964064e-4
GO:0010677 negative regulation of cellular carbohydrate metabolic process 3.980860e-4
GO:0071361 cellular response to ethanol 4.003476e-4
GO:0044062 regulation of excretion 4.178107e-4
GO:0071875 adrenergic receptor signaling pathway 4.178107e-4
GO:0045776 negative regulation of blood pressure 4.199172e-4
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 4.262151e-4
GO:0034114 regulation of heterotypic cell-cell adhesion 4.262151e-4
GO:0002376 immune system process 4.373671e-4
GO:0010989 negative regulation of low-density lipoprotein particle clearance 4.395413e-4
GO:0021592 fourth ventricle development 4.403905e-4
GO:0010896 regulation of triglyceride catabolic process 4.430927e-4
GO:0045777 positive regulation of blood pressure 4.519954e-4
GO:0071496 cellular response to external stimulus 4.595812e-4
GO:0021539 subthalamus development 4.918659e-4
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 4.926548e-4
GO:0002689 negative regulation of leukocyte chemotaxis 4.976490e-4
GO:0060009 Sertoli cell development 4.979795e-4
GO:0048625 myoblast cell fate commitment 5.003390e-4
GO:0002837 regulation of immune response to tumor cell 5.005378e-4
GO:0014013 regulation of gliogenesis 5.037991e-4
GO:0006665 sphingolipid metabolic process 5.108128e-4
GO:0071705 nitrogen compound transport 5.113130e-4
GO:0050707 regulation of cytokine secretion 5.190574e-4
GO:0090096 positive regulation of metanephric cap mesenchymal cell proliferation 5.224699e-4
GO:0022900 electron transport chain 5.233746e-4
GO:0010872 regulation of cholesterol esterification 5.329050e-4
GO:0051701 interaction with host 5.349520e-4
GO:0046784 intronless viral mRNA export from host nucleus 5.388265e-4
GO:0015858 nucleoside transport 5.388265e-4
GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback 5.423237e-4
GO:0000070 mitotic sister chromatid segregation 5.452888e-4
GO:0021846 cell proliferation in forebrain 5.467368e-4
GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine 5.534284e-4
GO:0010987 negative regulation of high-density lipoprotein particle clearance 5.586816e-4
GO:0010897 negative regulation of triglyceride catabolic process 5.586816e-4
GO:0006910 phagocytosis, recognition 5.602474e-4
GO:0000819 sister chromatid segregation 5.607428e-4
GO:0061048 negative regulation of branching involved in lung morphogenesis 5.616874e-4
GO:0045994 positive regulation of translational initiation by iron 5.616874e-4
GO:0034116 positive regulation of heterotypic cell-cell adhesion 5.616874e-4
GO:0002037 negative regulation of L-glutamate transport 5.616874e-4
GO:0010605 negative regulation of macromolecule metabolic process 5.647678e-4
GO:0006259 DNA metabolic process 5.692472e-4
GO:0048523 negative regulation of cellular process 5.927027e-4
GO:0051154 negative regulation of striated muscle cell differentiation 5.950631e-4
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 5.954043e-4
GO:0072061 inner medullary collecting duct development 6.010745e-4
GO:0072060 outer medullary collecting duct development 6.010745e-4
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 6.010745e-4
GO:0010608 posttranscriptional regulation of gene expression 6.093383e-4
GO:0022610 biological adhesion 6.166498e-4
GO:2000242 negative regulation of reproductive process 6.211894e-4
GO:0033057 multicellular organismal reproductive behavior 6.220551e-4
GO:0055062 phosphate ion homeostasis 6.229707e-4
GO:0070873 regulation of glycogen metabolic process 6.263475e-4
GO:0010873 positive regulation of cholesterol esterification 6.468357e-4
GO:0006694 steroid biosynthetic process 6.523038e-4
GO:0002250 adaptive immune response 6.571347e-4
GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 6.574024e-4
GO:0043388 positive regulation of DNA binding 6.607801e-4
GO:0035411 catenin import into nucleus 6.615799e-4
GO:0008016 regulation of heart contraction 6.640249e-4
GO:0052547 regulation of peptidase activity 6.733081e-4
GO:0051125 regulation of actin nucleation 6.839800e-4
GO:0007155 cell adhesion 6.843885e-4
GO:0010982 regulation of high-density lipoprotein particle clearance 6.959958e-4
GO:0030730 sequestering of triglyceride 6.959958e-4
GO:0048610 cellular process involved in reproduction 7.439297e-4
GO:0046520 sphingoid biosynthetic process 7.456829e-4
GO:0003073 regulation of systemic arterial blood pressure 7.618467e-4
GO:0010647 positive regulation of cell communication 7.663565e-4
GO:0045924 regulation of female receptivity 7.775003e-4
GO:0045428 regulation of nitric oxide biosynthetic process 7.886019e-4
GO:0002200 somatic diversification of immune receptors 7.963766e-4
GO:0050673 epithelial cell proliferation 8.088097e-4
GO:0009892 negative regulation of metabolic process 8.139542e-4
GO:0030168 platelet activation 8.178330e-4
GO:0071222 cellular response to lipopolysaccharide 8.307632e-4
GO:0042990 regulation of transcription factor import into nucleus 8.335608e-4
GO:0006109 regulation of carbohydrate metabolic process 8.393686e-4
GO:0007621 negative regulation of female receptivity 8.774061e-4
GO:0031424 keratinization 8.787813e-4
GO:0031507 heterochromatin formation 8.916219e-4
GO:0030317 sperm motility 8.925291e-4
GO:0046626 regulation of insulin receptor signaling pathway 8.959976e-4
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 8.984767e-4
GO:0032847 regulation of cellular pH reduction 9.041098e-4
GO:0051937 catecholamine transport 9.160783e-4
GO:0046006 regulation of activated T cell proliferation 9.176404e-4
GO:0002237 response to molecule of bacterial origin 9.196628e-4
GO:0048251 elastic fiber assembly 9.236453e-4
GO:0032274 gonadotropin secretion 9.262237e-4
GO:0048546 digestive tract morphogenesis 9.390764e-4
GO:0010675 regulation of cellular carbohydrate metabolic process 9.452180e-4
GO:0050792 regulation of viral reproduction 9.477216e-4
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 9.668328e-4
GO:0046513 ceramide biosynthetic process 9.681476e-4
GO:0002252 immune effector process 1.009108e-3
GO:0002833 positive regulation of response to biotic stimulus 1.019039e-3
GO:0032496 response to lipopolysaccharide 1.021865e-3
GO:0071702 organic substance transport 1.039935e-3
GO:0046466 membrane lipid catabolic process 1.040516e-3
GO:0006911 phagocytosis, engulfment 1.058270e-3
GO:0070995 NADPH oxidation 1.060869e-3
GO:0034435 cholesterol esterification 1.064356e-3
GO:0007126 meiosis 1.089700e-3
GO:0060312 regulation of blood vessel remodeling 1.102125e-3
GO:0006323 DNA packaging 1.102166e-3
GO:0015850 organic alcohol transport 1.103783e-3
GO:0044092 negative regulation of molecular function 1.115456e-3
GO:0032879 regulation of localization 1.146735e-3
GO:0043408 regulation of MAPKKK cascade 1.157357e-3
GO:0071219 cellular response to molecule of bacterial origin 1.158921e-3
GO:0032673 regulation of interleukin-4 production 1.163197e-3
GO:0060334 regulation of interferon-gamma-mediated signaling pathway 1.170724e-3
GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback 1.170724e-3
GO:0051321 meiotic cell cycle 1.196545e-3
GO:0032944 regulation of mononuclear cell proliferation 1.197917e-3
GO:0034440 lipid oxidation 1.200928e-3
GO:0051046 regulation of secretion 1.204566e-3
GO:0072053 renal inner medulla development 1.209654e-3
GO:0017144 drug metabolic process 1.212523e-3
GO:0030853 negative regulation of granulocyte differentiation 1.227343e-3
GO:0044140 negative regulation of growth of symbiont on or near host surface 1.229405e-3
GO:0006844 acyl carnitine transport 1.229405e-3
GO:0061099 negative regulation of protein tyrosine kinase activity 1.239297e-3
GO:0033194 response to hydroperoxide 1.239862e-3
GO:0060556 regulation of vitamin D biosynthetic process 1.241751e-3
GO:0046889 positive regulation of lipid biosynthetic process 1.241979e-3
GO:0002125 maternal aggressive behavior 1.242981e-3
GO:0007016 cytoskeletal anchoring at plasma membrane 1.247846e-3
GO:0032101 regulation of response to external stimulus 1.262556e-3
GO:0008152 metabolic process 1.302808e-3
GO:0050954 sensory perception of mechanical stimulus 1.309330e-3
GO:0002281 macrophage activation involved in immune response 1.318589e-3
GO:0044003 modification by symbiont of host morphology or physiology 1.318732e-3
GO:0006721 terpenoid metabolic process 1.336570e-3
GO:0002115 store-operated calcium entry 1.338815e-3
GO:0071803 positive regulation of podosome assembly 1.338815e-3
GO:0070201 regulation of establishment of protein localization 1.352329e-3
GO:0009112 nucleobase metabolic process 1.355197e-3
GO:0032859 activation of Ral GTPase activity 1.374018e-3
GO:0019229 regulation of vasoconstriction 1.391195e-3
GO:0051346 negative regulation of hydrolase activity 1.413544e-3
GO:0060010 Sertoli cell fate commitment 1.447370e-3
GO:0016098 monoterpenoid metabolic process 1.447370e-3
GO:0002275 myeloid cell activation involved in immune response 1.456831e-3
GO:0050670 regulation of lymphocyte proliferation 1.458528e-3
GO:0021570 rhombomere 4 development 1.472465e-3
GO:0006931 substrate-dependent cell migration, cell attachment to substrate 1.472465e-3
GO:2000273 positive regulation of receptor activity 1.486241e-3
GO:0046661 male sex differentiation 1.488937e-3
GO:0032456 endocytic recycling 1.492372e-3
GO:0071103 DNA conformation change 1.496730e-3
GO:0080135 regulation of cellular response to stress 1.506987e-3
GO:0009615 response to virus 1.514813e-3
GO:0032229 negative regulation of synaptic transmission, GABAergic 1.547561e-3
GO:0072054 renal outer medulla development 1.553244e-3
GO:0015931 nucleobase-containing compound transport 1.561218e-3
GO:0051984 positive regulation of chromosome segregation 1.575022e-3
GO:0034498 early endosome to Golgi transport 1.575022e-3
GO:0006420 arginyl-tRNA aminoacylation 1.575022e-3
GO:0034337 RNA folding 1.577503e-3
GO:0032722 positive regulation of chemokine production 1.580694e-3
GO:0046135 pyrimidine nucleoside catabolic process 1.582664e-3
GO:0000027 ribosomal large subunit assembly 1.597917e-3
GO:0046293 formaldehyde biosynthetic process 1.597917e-3
GO:0031324 negative regulation of cellular metabolic process 1.598134e-3
GO:0060262 negative regulation of N-terminal protein palmitoylation 1.598346e-3
GO:0016482 cytoplasmic transport 1.598346e-3
GO:0051103 DNA ligation involved in DNA repair 1.606554e-3
GO:2001021 negative regulation of response to DNA damage stimulus 1.608504e-3
GO:0008633 activation of pro-apoptotic gene products 1.611530e-3
GO:0010740 positive regulation of intracellular protein kinase cascade 1.623353e-3
GO:0072659 protein localization in plasma membrane 1.640238e-3
GO:0015884 folic acid transport 1.642494e-3
GO:0043200 response to amino acid stimulus 1.656273e-3
GO:0006937 regulation of muscle contraction 1.686224e-3
GO:0023056 positive regulation of signaling 1.688740e-3
GO:0044106 cellular amine metabolic process 1.689608e-3
GO:0010810 regulation of cell-substrate adhesion 1.699643e-3
GO:0032501 multicellular organismal process 1.721464e-3
GO:0010646 regulation of cell communication 1.778175e-3
GO:0045429 positive regulation of nitric oxide biosynthetic process 1.789279e-3
GO:0032674 regulation of interleukin-5 production 1.814861e-3