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Novel motif:4

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name:motif4_TGTCTA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0050896 response to stimulus 1.061427e-40
GO:0051716 cellular response to stimulus 3.597545e-26
GO:0007154 cell communication 6.114364e-23
GO:0023052 signaling 7.250907e-23
GO:0007275 multicellular organismal development 7.586837e-23
GO:0032502 developmental process 1.593986e-22
GO:0032501 multicellular organismal process 8.779185e-22
GO:0048513 organ development 2.338620e-21
GO:0007165 signal transduction 3.054254e-21
GO:0042221 response to chemical stimulus 1.731005e-20
GO:2000191 regulation of fatty acid transport 2.211606e-20
GO:0009628 response to abiotic stimulus 1.067967e-19
GO:2000026 regulation of multicellular organismal development 1.966766e-19
GO:0048731 system development 4.252886e-19
GO:0051592 response to calcium ion 5.560645e-19
GO:0050793 regulation of developmental process 1.366845e-18
GO:0048856 anatomical structure development 1.526914e-18
GO:0009266 response to temperature stimulus 1.873171e-18
GO:0019220 regulation of phosphate metabolic process 2.470122e-18
GO:0001932 regulation of protein phosphorylation 1.143521e-17
GO:0042325 regulation of phosphorylation 1.357269e-17
GO:0009408 response to heat 1.971436e-17
GO:0051239 regulation of multicellular organismal process 4.074564e-17
GO:0010038 response to metal ion 1.013005e-16
GO:0006950 response to stress 2.249493e-16
GO:0006955 immune response 2.767434e-16
GO:0009888 tissue development 5.391328e-16
GO:0034605 cellular response to heat 6.034910e-16
GO:0031399 regulation of protein modification process 7.019878e-16
GO:0048583 regulation of response to stimulus 1.026758e-15
GO:0002688 regulation of leukocyte chemotaxis 1.125403e-15
GO:0007166 cell surface receptor linked signaling pathway 1.649979e-15
GO:0002690 positive regulation of leukocyte chemotaxis 1.928044e-15
GO:0002604 regulation of dendritic cell antigen processing and presentation 2.068993e-15
GO:0042060 wound healing 2.480393e-15
GO:0001775 cell activation 2.851787e-15
GO:0032103 positive regulation of response to external stimulus 3.374052e-15
GO:0016525 negative regulation of angiogenesis 3.465216e-15
GO:0045765 regulation of angiogenesis 3.981083e-15
GO:0002577 regulation of antigen processing and presentation 4.201400e-15
GO:0030168 platelet activation 7.288722e-15
GO:0002576 platelet degranulation 7.672589e-15
GO:0007155 cell adhesion 1.226087e-14
GO:0002376 immune system process 1.618628e-14
GO:0032890 regulation of organic acid transport 1.888422e-14
GO:0043549 regulation of kinase activity 2.284509e-14
GO:0006916 anti-apoptosis 2.953941e-14
GO:0032940 secretion by cell 3.861491e-14
GO:0010627 regulation of intracellular protein kinase cascade 3.949620e-14
GO:0007596 blood coagulation 6.524004e-14
GO:0010758 regulation of macrophage chemotaxis 7.160672e-14
GO:0045859 regulation of protein kinase activity 7.981059e-14
GO:0007599 hemostasis 1.589309e-13
GO:0048683 regulation of collateral sprouting of intact axon in response to injury 1.642438e-13
GO:0051338 regulation of transferase activity 2.083331e-13
GO:0006887 exocytosis 2.328222e-13
GO:0009611 response to wounding 2.338467e-13
GO:0002687 positive regulation of leukocyte migration 2.689433e-13
GO:0046903 secretion 2.838259e-13
GO:0061041 regulation of wound healing 2.923303e-13
GO:0010759 positive regulation of macrophage chemotaxis 3.518336e-13
GO:0010648 negative regulation of cell communication 3.977773e-13
GO:0023057 negative regulation of signaling 6.520186e-13
GO:0032308 positive regulation of prostaglandin secretion 9.811957e-13
GO:0002685 regulation of leukocyte migration 1.062066e-12
GO:0002544 chronic inflammatory response 1.313304e-12
GO:0009968 negative regulation of signal transduction 1.590255e-12
GO:0042327 positive regulation of phosphorylation 1.603656e-12
GO:0043030 regulation of macrophage activation 1.608909e-12
GO:0048520 positive regulation of behavior 1.611596e-12
GO:0071675 regulation of mononuclear cell migration 1.616904e-12
GO:0030193 regulation of blood coagulation 1.942715e-12
GO:0003008 system process 2.081106e-12
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 2.123896e-12
GO:0009966 regulation of signal transduction 3.254396e-12
GO:0043406 positive regulation of MAP kinase activity 3.522139e-12
GO:0043405 regulation of MAP kinase activity 3.593676e-12
GO:0045937 positive regulation of phosphate metabolic process 4.116823e-12
GO:0050921 positive regulation of chemotaxis 4.301128e-12
GO:0048585 negative regulation of response to stimulus 5.284662e-12
GO:2000193 positive regulation of fatty acid transport 5.459047e-12
GO:0010757 negative regulation of plasminogen activation 6.032430e-12
GO:0000187 activation of MAPK activity 7.259538e-12
GO:0071622 regulation of granulocyte chemotaxis 7.733129e-12
GO:0007417 central nervous system development 1.036696e-11
GO:0032844 regulation of homeostatic process 1.378270e-11
GO:0010740 positive regulation of intracellular protein kinase cascade 1.380986e-11
GO:0070163 regulation of adiponectin secretion 1.412346e-11
GO:0032722 positive regulation of chemokine production 1.445860e-11
GO:0050818 regulation of coagulation 2.418166e-11
GO:0065008 regulation of biological quality 2.461252e-11
GO:0032268 regulation of cellular protein metabolic process 2.571795e-11
GO:0010193 response to ozone 2.793654e-11
GO:0050790 regulation of catalytic activity 2.930764e-11
GO:0022603 regulation of anatomical structure morphogenesis 2.936323e-11
GO:0010755 regulation of plasminogen activation 3.136189e-11
GO:0050878 regulation of body fluid levels 3.197859e-11
GO:0032642 regulation of chemokine production 3.284939e-11
GO:0010751 negative regulation of nitric oxide mediated signal transduction 3.315566e-11
GO:0043652 engulfment of apoptotic cell 3.315566e-11
GO:0010754 negative regulation of cGMP-mediated signaling 3.315566e-11
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 3.315566e-11
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 3.315566e-11
GO:0048739 cardiac muscle fiber development 3.342788e-11
GO:0051606 detection of stimulus 3.482675e-11
GO:0042346 positive regulation of NF-kappaB import into nucleus 3.734943e-11
GO:0009743 response to carbohydrate stimulus 3.757862e-11
GO:0032101 regulation of response to external stimulus 3.782758e-11
GO:0050794 regulation of cellular process 4.273739e-11
GO:0050789 regulation of biological process 4.324108e-11
GO:0032892 positive regulation of organic acid transport 4.720963e-11
GO:0010646 regulation of cell communication 5.255238e-11
GO:0001714 endodermal cell fate specification 5.509778e-11
GO:0070164 negative regulation of adiponectin secretion 5.511256e-11
GO:0060355 positive regulation of cell adhesion molecule production 5.511256e-11
GO:0035505 positive regulation of myosin light chain kinase activity 5.511256e-11
GO:0050920 regulation of chemotaxis 6.355077e-11
GO:0050865 regulation of cell activation 6.709112e-11
GO:0009746 response to hexose stimulus 6.867589e-11
GO:0051093 negative regulation of developmental process 7.264681e-11
GO:0002684 positive regulation of immune system process 8.041211e-11
GO:0048584 positive regulation of response to stimulus 9.641215e-11
GO:0006952 defense response 1.170585e-10
GO:0050974 detection of mechanical stimulus involved in sensory perception 1.233639e-10
GO:0010955 negative regulation of protein processing 1.250805e-10
GO:0008285 negative regulation of cell proliferation 1.283534e-10
GO:0010033 response to organic substance 1.342809e-10
GO:0034284 response to monosaccharide stimulus 1.393132e-10
GO:0051246 regulation of protein metabolic process 1.415587e-10
GO:0009581 detection of external stimulus 1.459111e-10
GO:0050877 neurological system process 1.783992e-10
GO:0001660 fever generation 2.046312e-10
GO:0042552 myelination 2.063644e-10
GO:0055082 cellular chemical homeostasis 2.149299e-10
GO:0071902 positive regulation of protein serine/threonine kinase activity 2.150059e-10
GO:0001936 regulation of endothelial cell proliferation 2.457892e-10
GO:0048468 cell development 2.515030e-10
GO:0051707 response to other organism 2.760694e-10
GO:0010574 regulation of vascular endothelial growth factor production 2.972619e-10
GO:0071900 regulation of protein serine/threonine kinase activity 3.379921e-10
GO:0010035 response to inorganic substance 3.438201e-10
GO:0045595 regulation of cell differentiation 3.523145e-10
GO:0051240 positive regulation of multicellular organismal process 3.569475e-10
GO:0080134 regulation of response to stress 3.615820e-10
GO:0010470 regulation of gastrulation 3.625572e-10
GO:0002694 regulation of leukocyte activation 3.631835e-10
GO:0050982 detection of mechanical stimulus 3.876680e-10
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 4.109981e-10
GO:0009653 anatomical structure morphogenesis 4.186336e-10
GO:0045410 positive regulation of interleukin-6 biosynthetic process 4.254350e-10
GO:0002696 positive regulation of leukocyte activation 4.527553e-10
GO:0010647 positive regulation of cell communication 5.197613e-10
GO:0033591 response to L-ascorbic acid 5.227847e-10
GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback 5.272209e-10
GO:0048869 cellular developmental process 5.739876e-10
GO:0050795 regulation of behavior 6.085000e-10
GO:0045860 positive regulation of protein kinase activity 6.151485e-10
GO:0045766 positive regulation of angiogenesis 7.660905e-10
GO:0032655 regulation of interleukin-12 production 8.490838e-10
GO:0023051 regulation of signaling 8.873949e-10
GO:0090287 regulation of cellular response to growth factor stimulus 8.918242e-10
GO:0034762 regulation of transmembrane transport 9.509062e-10
GO:0009749 response to glucose stimulus 9.680656e-10
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 1.003652e-9
GO:0065007 biological regulation 1.042752e-9
GO:0023056 positive regulation of signaling 1.067855e-9
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 1.158781e-9
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 1.201168e-9
GO:0070887 cellular response to chemical stimulus 1.310731e-9
GO:0051409 response to nitrosative stress 1.327040e-9
GO:0043537 negative regulation of blood vessel endothelial cell migration 1.336469e-9
GO:0035556 intracellular signal transduction 1.364425e-9
GO:0014866 skeletal myofibril assembly 1.382397e-9
GO:0050771 negative regulation of axonogenesis 1.425294e-9
GO:0071322 cellular response to carbohydrate stimulus 1.438368e-9
GO:0050867 positive regulation of cell activation 1.504974e-9
GO:0000165 MAPKKK cascade 1.635822e-9
GO:0033674 positive regulation of kinase activity 1.708527e-9
GO:0009967 positive regulation of signal transduction 1.867643e-9
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 2.169582e-9
GO:0051704 multi-organism process 2.248991e-9
GO:0001678 cellular glucose homeostasis 2.338464e-9
GO:0050776 regulation of immune response 2.451815e-9
GO:0065009 regulation of molecular function 2.590944e-9
GO:0072507 divalent inorganic cation homeostasis 2.690544e-9
GO:0006873 cellular ion homeostasis 2.747608e-9
GO:0072503 cellular divalent inorganic cation homeostasis 3.170381e-9
GO:0002682 regulation of immune system process 3.479470e-9
GO:0055074 calcium ion homeostasis 3.560229e-9
GO:0006874 cellular calcium ion homeostasis 3.791328e-9
GO:0018149 peptide cross-linking 3.914503e-9
GO:0071333 cellular response to glucose stimulus 3.941247e-9
GO:0045080 positive regulation of chemokine biosynthetic process 4.343379e-9
GO:2000758 positive regulation of peptidyl-lysine acetylation 4.777310e-9
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 4.886754e-9
GO:0048519 negative regulation of biological process 5.092369e-9
GO:0001937 negative regulation of endothelial cell proliferation 5.294768e-9
GO:0030154 cell differentiation 5.346841e-9
GO:0050801 ion homeostasis 5.696527e-9
GO:0032914 positive regulation of transforming growth factor beta1 production 6.042289e-9
GO:0071822 protein complex subunit organization 6.739266e-9
GO:0010596 negative regulation of endothelial cell migration 6.821681e-9
GO:0035234 germ cell programmed cell death 6.952561e-9
GO:0035691 macrophage migration inhibitory factor signaling pathway 7.325172e-9
GO:0010332 response to gamma radiation 8.058762e-9
GO:0019228 regulation of action potential in neuron 8.195587e-9
GO:0051480 cytosolic calcium ion homeostasis 8.716072e-9
GO:0043032 positive regulation of macrophage activation 8.732179e-9
GO:0007076 mitotic chromosome condensation 8.913425e-9
GO:0022402 cell cycle process 9.288223e-9
GO:0060548 negative regulation of cell death 9.519037e-9
GO:0030241 skeletal muscle myosin thick filament assembly 9.984772e-9
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1.028482e-8
GO:0007186 G-protein coupled receptor protein signaling pathway 1.041895e-8
GO:0060412 ventricular septum morphogenesis 1.055326e-8
GO:0040011 locomotion 1.075411e-8
GO:0001711 endodermal cell fate commitment 1.094738e-8
GO:0051895 negative regulation of focal adhesion assembly 1.162126e-8
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 1.203873e-8
GO:0009607 response to biotic stimulus 1.260342e-8
GO:0032755 positive regulation of interleukin-6 production 1.260906e-8
GO:0030155 regulation of cell adhesion 1.261840e-8
GO:0043277 apoptotic cell clearance 1.262141e-8
GO:0051347 positive regulation of transferase activity 1.279908e-8
GO:0048646 anatomical structure formation involved in morphogenesis 1.280187e-8
GO:0035690 cellular response to drug 1.286675e-8
GO:0008366 axon ensheathment 1.379611e-8
GO:0048523 negative regulation of cellular process 1.503258e-8
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 1.627878e-8
GO:0051179 localization 1.691957e-8
GO:0048729 tissue morphogenesis 1.735469e-8
GO:0032695 negative regulation of interleukin-12 production 1.756736e-8
GO:0043069 negative regulation of programmed cell death 1.777678e-8
GO:0042127 regulation of cell proliferation 1.916360e-8
GO:0045087 innate immune response 1.946441e-8
GO:0060638 mesenchymal-epithelial cell signaling 2.035105e-8
GO:0048878 chemical homeostasis 2.062032e-8
GO:0007243 intracellular protein kinase cascade 2.255034e-8
GO:0032570 response to progesterone stimulus 2.255529e-8
GO:0019725 cellular homeostasis 2.628681e-8
GO:0010763 positive regulation of fibroblast migration 2.657807e-8
GO:0009605 response to external stimulus 2.675715e-8
GO:0031345 negative regulation of cell projection organization 2.682819e-8
GO:0071840 cellular component organization or biogenesis 2.759604e-8
GO:0070271 protein complex biogenesis 2.904315e-8
GO:0048747 muscle fiber development 2.985349e-8
GO:0016043 cellular component organization 3.311612e-8
GO:0034116 positive regulation of heterotypic cell-cell adhesion 3.314596e-8
GO:0051094 positive regulation of developmental process 3.403110e-8
GO:0051247 positive regulation of protein metabolic process 3.508897e-8
GO:0032368 regulation of lipid transport 3.602140e-8
GO:0045073 regulation of chemokine biosynthetic process 3.605109e-8
GO:0043066 negative regulation of apoptosis 3.609745e-8
GO:0042993 positive regulation of transcription factor import into nucleus 3.879796e-8
GO:0070372 regulation of ERK1 and ERK2 cascade 3.958043e-8
GO:0030240 skeletal muscle thin filament assembly 4.127670e-8
GO:0007204 elevation of cytosolic calcium ion concentration 4.181463e-8
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 5.112888e-8
GO:0000819 sister chromatid segregation 5.268442e-8
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 5.460407e-8
GO:0000070 mitotic sister chromatid segregation 5.561963e-8
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 5.725480e-8
GO:0033198 response to ATP 6.010070e-8
GO:0031344 regulation of cell projection organization 6.108776e-8
GO:0006461 protein complex assembly 6.519665e-8
GO:0032270 positive regulation of cellular protein metabolic process 8.081839e-8
GO:0044057 regulation of system process 8.931554e-8
GO:0016477 cell migration 8.935778e-8
GO:0033129 positive regulation of histone phosphorylation 9.121734e-8
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 9.286947e-8
GO:0007601 visual perception 1.008439e-7
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 1.026889e-7
GO:0032026 response to magnesium ion 1.044387e-7
GO:0042063 gliogenesis 1.081508e-7
GO:0031401 positive regulation of protein modification process 1.102768e-7
GO:0022008 neurogenesis 1.201391e-7
GO:0032370 positive regulation of lipid transport 1.217063e-7
GO:0048087 positive regulation of developmental pigmentation 1.254205e-7
GO:0090331 negative regulation of platelet aggregation 1.328020e-7
GO:0061110 dense core granule biogenesis 1.328020e-7
GO:0061108 seminal vesicle epithelium development 1.328020e-7
GO:0042628 mating plug formation 1.328020e-7
GO:0050680 negative regulation of epithelial cell proliferation 1.423698e-7
GO:0046825 regulation of protein export from nucleus 1.441940e-7
GO:0050953 sensory perception of light stimulus 1.446806e-7
GO:0001508 regulation of action potential 1.770874e-7
GO:0045664 regulation of neuron differentiation 1.896696e-7
GO:0051282 regulation of sequestering of calcium ion 2.002917e-7
GO:0071345 cellular response to cytokine stimulus 2.089972e-7
GO:0042534 regulation of tumor necrosis factor biosynthetic process 2.253625e-7
GO:2000145 regulation of cell motility 2.267466e-7
GO:0045636 positive regulation of melanocyte differentiation 2.492279e-7
GO:0015791 polyol transport 2.496051e-7
GO:0030194 positive regulation of blood coagulation 2.529126e-7
GO:0051918 negative regulation of fibrinolysis 2.668236e-7
GO:0006468 protein phosphorylation 2.671332e-7
GO:0042108 positive regulation of cytokine biosynthetic process 2.809909e-7
GO:0010631 epithelial cell migration 2.864160e-7
GO:0046688 response to copper ion 2.905433e-7
GO:0070613 regulation of protein processing 2.909223e-7
GO:0014805 smooth muscle adaptation 2.939712e-7
GO:0009582 detection of abiotic stimulus 2.946188e-7
GO:0001934 positive regulation of protein phosphorylation 3.077450e-7
GO:0045124 regulation of bone resorption 3.220138e-7
GO:0070665 positive regulation of leukocyte proliferation 3.284869e-7
GO:0001819 positive regulation of cytokine production 3.314464e-7
GO:0002830 positive regulation of type 2 immune response 3.339081e-7
GO:0042446 hormone biosynthetic process 3.419453e-7
GO:0032757 positive regulation of interleukin-8 production 3.485081e-7
GO:0051649 establishment of localization in cell 3.524418e-7
GO:2000021 regulation of ion homeostasis 3.602971e-7
GO:0006928 cellular component movement 3.648690e-7
GO:0071637 regulation of monocyte chemotactic protein-1 production 3.740127e-7
GO:0072358 cardiovascular system development 3.798019e-7
GO:0042345 regulation of NF-kappaB import into nucleus 3.806848e-7
GO:0043933 macromolecular complex subunit organization 3.902715e-7
GO:0006875 cellular metal ion homeostasis 3.981521e-7
GO:0009617 response to bacterium 4.211281e-7
GO:0010741 negative regulation of intracellular protein kinase cascade 4.242883e-7
GO:0033127 regulation of histone phosphorylation 4.481912e-7
GO:0032675 regulation of interleukin-6 production 4.494917e-7
GO:0030335 positive regulation of cell migration 4.603587e-7
GO:0007267 cell-cell signaling 4.736155e-7
GO:0051234 establishment of localization 4.842024e-7
GO:0080135 regulation of cellular response to stress 4.892898e-7
GO:0006911 phagocytosis, engulfment 4.947028e-7
GO:0040012 regulation of locomotion 5.432208e-7
GO:0032908 regulation of transforming growth factor beta1 production 5.480348e-7
GO:0046627 negative regulation of insulin receptor signaling pathway 5.602620e-7
GO:0035725 sodium ion transmembrane transport 5.817047e-7
GO:0048870 cell motility 5.862484e-7
GO:0014050 negative regulation of glutamate secretion 6.119349e-7
GO:0050778 positive regulation of immune response 6.172856e-7
GO:0048769 sarcomerogenesis 6.174830e-7
GO:0045408 regulation of interleukin-6 biosynthetic process 6.247198e-7
GO:2000147 positive regulation of cell motility 6.612759e-7
GO:0048732 gland development 6.800868e-7
GO:0090310 negative regulation of methylation-dependent chromatin silencing 6.859609e-7
GO:0030728 ovulation 7.103206e-7
GO:0030593 neutrophil chemotaxis 7.379829e-7
GO:0051705 behavioral interaction between organisms 7.733021e-7
GO:0007399 nervous system development 7.789386e-7
GO:0043500 muscle adaptation 7.883850e-7
GO:0051917 regulation of fibrinolysis 7.992996e-7
GO:0051049 regulation of transport 8.220654e-7
GO:0051092 positive regulation of NF-kappaB transcription factor activity 8.593260e-7
GO:0045596 negative regulation of cell differentiation 9.071608e-7
GO:0007566 embryo implantation 9.156535e-7
GO:0048685 negative regulation of collateral sprouting of intact axon in response to injury 9.339547e-7
GO:0032879 regulation of localization 9.384390e-7
GO:0050870 positive regulation of T cell activation 9.813055e-7
GO:2001020 regulation of response to DNA damage stimulus 9.843034e-7
GO:0055065 metal ion homeostasis 9.883139e-7
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 1.011421e-6
GO:0033280 response to vitamin D 1.013083e-6
GO:0006796 phosphate-containing compound metabolic process 1.047013e-6
GO:0008219 cell death 1.054639e-6
GO:0007420 brain development 1.065670e-6
GO:0046850 regulation of bone remodeling 1.111888e-6
GO:0033059 cellular pigmentation 1.130888e-6
GO:0034097 response to cytokine stimulus 1.165695e-6
GO:0010466 negative regulation of peptidase activity 1.220025e-6
GO:0030730 sequestering of triglyceride 1.226147e-6
GO:0016265 death 1.255338e-6
GO:0051046 regulation of secretion 1.281235e-6
GO:0009314 response to radiation 1.340402e-6
GO:0071346 cellular response to interferon-gamma 1.360580e-6
GO:0016310 phosphorylation 1.469512e-6
GO:0060558 regulation of calcidiol 1-monooxygenase activity 1.471349e-6
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 1.485028e-6
GO:0045861 negative regulation of proteolysis 1.549623e-6
GO:0003007 heart morphogenesis 1.590665e-6
GO:0040017 positive regulation of locomotion 1.602079e-6
GO:0030003 cellular cation homeostasis 1.663253e-6
GO:0051893 regulation of focal adhesion assembly 1.666202e-6
GO:0051209 release of sequestered calcium ion into cytosol 1.683631e-6
GO:0044060 regulation of endocrine process 1.691297e-6
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 1.694521e-6
GO:0032874 positive regulation of stress-activated MAPK cascade 1.732764e-6
GO:0015793 glycerol transport 1.769147e-6
GO:0045634 regulation of melanocyte differentiation 1.777945e-6
GO:0050820 positive regulation of coagulation 1.827758e-6
GO:0050678 regulation of epithelial cell proliferation 1.893913e-6
GO:0007179 transforming growth factor beta receptor signaling pathway 2.024888e-6
GO:0071310 cellular response to organic substance 2.028193e-6
GO:0048608 reproductive structure development 2.067908e-6
GO:0000087 M phase of mitotic cell cycle 2.068013e-6
GO:0010575 positive regulation vascular endothelial growth factor production 2.131219e-6
GO:0052572 response to host immune response 2.133892e-6
GO:0034405 response to fluid shear stress 2.154343e-6
GO:0051270 regulation of cellular component movement 2.165285e-6
GO:0007568 aging 2.197715e-6
GO:0001659 temperature homeostasis 2.203446e-6
GO:0010975 regulation of neuron projection development 2.232610e-6
GO:0007507 heart development 2.460495e-6
GO:0055001 muscle cell development 2.466382e-6
GO:0003221 right ventricular cardiac muscle tissue morphogenesis 2.479991e-6
GO:0032891 negative regulation of organic acid transport 2.618132e-6
GO:0051272 positive regulation of cellular component movement 2.857831e-6
GO:0042592 homeostatic process 2.929388e-6
GO:0070374 positive regulation of ERK1 and ERK2 cascade 3.019452e-6
GO:0030001 metal ion transport 3.099054e-6
GO:0043535 regulation of blood vessel endothelial cell migration 3.145246e-6
GO:0060429 epithelium development 3.191099e-6
GO:0030334 regulation of cell migration 3.210902e-6
GO:0000279 M phase 3.300380e-6
GO:0035066 positive regulation of histone acetylation 3.359496e-6
GO:0055003 cardiac myofibril assembly 3.415756e-6
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 3.451857e-6
GO:0007050 cell cycle arrest 3.739173e-6
GO:0002237 response to molecule of bacterial origin 3.815647e-6
GO:0015672 monovalent inorganic cation transport 3.825339e-6
GO:0043408 regulation of MAPKKK cascade 3.869768e-6
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 4.045872e-6
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 4.049185e-6
GO:0043086 negative regulation of catalytic activity 4.067649e-6
GO:0002439 chronic inflammatory response to antigenic stimulus 4.071641e-6
GO:0042307 positive regulation of protein import into nucleus 4.079642e-6
GO:0035176 social behavior 4.351801e-6
GO:0032989 cellular component morphogenesis 4.581097e-6
GO:0051450 myoblast proliferation 4.581499e-6
GO:0006633 fatty acid biosynthetic process 4.698347e-6
GO:0008016 regulation of heart contraction 4.763854e-6
GO:0043085 positive regulation of catalytic activity 4.883501e-6
GO:0007049 cell cycle 4.900295e-6
GO:0055080 cation homeostasis 4.952388e-6
GO:0051054 positive regulation of DNA metabolic process 5.217256e-6
GO:0006810 transport 5.233384e-6
GO:0009987 cellular process 5.527649e-6
GO:0012501 programmed cell death 5.553794e-6
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 5.560926e-6
GO:0030239 myofibril assembly 5.616062e-6
GO:0090308 regulation of methylation-dependent chromatin silencing 5.672957e-6
GO:0042391 regulation of membrane potential 5.743457e-6
GO:0001706 endoderm formation 5.993525e-6
GO:0051249 regulation of lymphocyte activation 6.046350e-6
GO:0051047 positive regulation of secretion 6.124293e-6
GO:0071901 negative regulation of protein serine/threonine kinase activity 6.208233e-6
GO:0014706 striated muscle tissue development 6.271850e-6
GO:0051251 positive regulation of lymphocyte activation 6.380611e-6
GO:0035270 endocrine system development 6.397220e-6
GO:0050906 detection of stimulus involved in sensory perception 6.542938e-6
GO:0007067 mitosis 6.750543e-6
GO:0043536 positive regulation of blood vessel endothelial cell migration 6.775309e-6
GO:0006812 cation transport 6.867634e-6
GO:0051241 negative regulation of multicellular organismal process 6.980293e-6
GO:0050863 regulation of T cell activation 7.435082e-6
GO:0048699 generation of neurons 7.439045e-6
GO:0060411 cardiac septum morphogenesis 7.535400e-6
GO:0022407 regulation of cell-cell adhesion 7.589579e-6
GO:0002683 negative regulation of immune system process 7.700492e-6
GO:0031622 positive regulation of fever generation 7.706180e-6
GO:0045616 regulation of keratinocyte differentiation 8.095940e-6
GO:0048070 regulation of developmental pigmentation 8.142872e-6
GO:0060754 positive regulation of mast cell chemotaxis 8.169133e-6
GO:0008354 germ cell migration 8.216811e-6
GO:0003006 developmental process involved in reproduction 8.252888e-6
GO:0090130 tissue migration 8.329860e-6
GO:0034114 regulation of heterotypic cell-cell adhesion 8.329860e-6
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 8.329860e-6
GO:0035162 embryonic hemopoiesis 8.373611e-6
GO:0070668 positive regulation of mast cell proliferation 8.373859e-6
GO:0010001 glial cell differentiation 8.611123e-6
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 8.635724e-6
GO:0010829 negative regulation of glucose transport 8.692041e-6
GO:0019226 transmission of nerve impulse 8.714475e-6
GO:0048670 regulation of collateral sprouting 8.721949e-6
GO:0051960 regulation of nervous system development 8.844449e-6
GO:0065003 macromolecular complex assembly 8.901035e-6
GO:0021782 glial cell development 8.972158e-6
GO:0034764 positive regulation of transmembrane transport 9.197836e-6
GO:0010941 regulation of cell death 9.450665e-6
GO:0052033 pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity 9.455432e-6
GO:0007565 female pregnancy 9.633628e-6
GO:0043407 negative regulation of MAP kinase activity 9.970918e-6
GO:0043067 regulation of programmed cell death 1.021585e-5
GO:0048285 organelle fission 1.044385e-5
GO:0002906 negative regulation of mature B cell apoptosis 1.061048e-5
GO:0046883 regulation of hormone secretion 1.064110e-5
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1.077430e-5
GO:0031652 positive regulation of heat generation 1.146766e-5
GO:0032648 regulation of interferon-beta production 1.156394e-5
GO:0032496 response to lipopolysaccharide 1.158806e-5
GO:0034110 regulation of homotypic cell-cell adhesion 1.171727e-5
GO:0000959 mitochondrial RNA metabolic process 1.191699e-5
GO:0010927 cellular component assembly involved in morphogenesis 1.194020e-5
GO:0043163 cell envelope organization 1.208567e-5
GO:0055002 striated muscle cell development 1.218724e-5
GO:0051384 response to glucocorticoid stimulus 1.228798e-5
GO:0033157 regulation of intracellular protein transport 1.242834e-5
GO:0060174 limb bud formation 1.276289e-5
GO:0042663 regulation of endodermal cell fate specification 1.305947e-5
GO:0060478 acrosomal vesicle exocytosis 1.316218e-5
GO:0051223 regulation of protein transport 1.364933e-5
GO:0002579 positive regulation of antigen processing and presentation 1.431885e-5
GO:0042493 response to drug 1.456825e-5
GO:0019827 stem cell maintenance 1.462918e-5
GO:0009887 organ morphogenesis 1.509371e-5
GO:0007600 sensory perception 1.535307e-5
GO:0060907 positive regulation of macrophage cytokine production 1.566355e-5


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0050896 response to stimulus 1.649570e-25
GO:0006950 response to stress 3.856190e-25
GO:0002376 immune system process 1.163702e-23
GO:0009611 response to wounding 1.700537e-18
GO:0032501 multicellular organismal process 3.707699e-18
GO:0006955 immune response 2.580596e-17
GO:0042221 response to chemical stimulus 4.009167e-17
GO:0042060 wound healing 3.218106e-16
GO:0048513 organ development 1.621226e-15
GO:0042127 regulation of cell proliferation 7.098674e-15
GO:0002252 immune effector process 9.453453e-15
GO:0051247 positive regulation of protein metabolic process 1.012347e-14
GO:0001775 cell activation 2.244677e-14
GO:0010033 response to organic substance 8.503933e-14
GO:0009605 response to external stimulus 8.737202e-14
GO:0006952 defense response 2.662359e-13
GO:0051716 cellular response to stimulus 3.940026e-13
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 5.869391e-13
GO:0048731 system development 1.005607e-12
GO:0009308 amine metabolic process 1.686989e-12
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 2.762929e-12
GO:0032270 positive regulation of cellular protein metabolic process 3.374929e-12
GO:0032940 secretion by cell 4.754038e-12
GO:0051179 localization 5.858280e-12
GO:0002684 positive regulation of immune system process 6.583226e-12
GO:0023056 positive regulation of signaling 7.343721e-12
GO:0048856 anatomical structure development 9.600323e-12
GO:0032879 regulation of localization 1.000576e-11
GO:0007599 hemostasis 1.590836e-11
GO:0065008 regulation of biological quality 1.769839e-11
GO:0008285 negative regulation of cell proliferation 1.828811e-11
GO:0042327 positive regulation of phosphorylation 1.976244e-11
GO:0009887 organ morphogenesis 2.204306e-11
GO:0010647 positive regulation of cell communication 2.313555e-11
GO:0008284 positive regulation of cell proliferation 2.761603e-11
GO:0051049 regulation of transport 2.946053e-11
GO:0009967 positive regulation of signal transduction 3.008167e-11
GO:0007154 cell communication 3.385000e-11
GO:0006810 transport 4.364745e-11
GO:0051246 regulation of protein metabolic process 5.008691e-11
GO:0051234 establishment of localization 5.124151e-11
GO:0031401 positive regulation of protein modification process 5.175000e-11
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 5.268016e-11
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 5.327082e-11
GO:0030162 regulation of proteolysis 5.650555e-11
GO:0045321 leukocyte activation 5.723034e-11
GO:0045937 positive regulation of phosphate metabolic process 6.844942e-11
GO:0050678 regulation of epithelial cell proliferation 7.488096e-11
GO:0048518 positive regulation of biological process 1.182144e-10
GO:0048522 positive regulation of cellular process 1.293320e-10
GO:0048584 positive regulation of response to stimulus 1.352182e-10
GO:0009612 response to mechanical stimulus 1.567842e-10
GO:0009914 hormone transport 1.633116e-10
GO:0007596 blood coagulation 1.633116e-10
GO:0003008 system process 1.685959e-10
GO:0051649 establishment of localization in cell 1.812948e-10
GO:0032502 developmental process 2.994191e-10
GO:0001934 positive regulation of protein phosphorylation 3.311453e-10
GO:0051704 multi-organism process 3.817671e-10
GO:0007275 multicellular organismal development 4.311188e-10
GO:0002443 leukocyte mediated immunity 7.029356e-10
GO:0023052 signaling 7.323078e-10
GO:0050776 regulation of immune response 7.856063e-10
GO:0001932 regulation of protein phosphorylation 1.470952e-9
GO:0050778 positive regulation of immune response 1.870514e-9
GO:0046427 positive regulation of JAK-STAT cascade 2.083123e-9
GO:0044106 cellular amine metabolic process 2.271468e-9
GO:0010604 positive regulation of macromolecule metabolic process 2.458243e-9
GO:0031399 regulation of protein modification process 2.581284e-9
GO:0070887 cellular response to chemical stimulus 3.870972e-9
GO:0042129 regulation of T cell proliferation 4.282408e-9
GO:0021543 pallium development 4.421062e-9
GO:0051045 negative regulation of membrane protein ectodomain proteolysis 4.669017e-9
GO:0007507 heart development 5.703948e-9
GO:0010740 positive regulation of intracellular protein kinase cascade 6.182797e-9
GO:0009719 response to endogenous stimulus 6.241239e-9
GO:0019370 leukotriene biosynthetic process 6.615830e-9
GO:0009790 embryo development 6.692843e-9
GO:0048568 embryonic organ development 7.726769e-9
GO:0015837 amine transport 7.960799e-9
GO:0009888 tissue development 8.031069e-9
GO:0035886 vascular smooth muscle cell differentiation 8.309150e-9
GO:0046903 secretion 8.681127e-9
GO:0042102 positive regulation of T cell proliferation 9.258491e-9
GO:0050870 positive regulation of T cell activation 9.383090e-9
GO:0065007 biological regulation 1.149450e-8
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 1.400953e-8
GO:0019220 regulation of phosphate metabolic process 1.735071e-8
GO:0006959 humoral immune response 2.371842e-8
GO:0012502 induction of programmed cell death 2.403150e-8
GO:0046631 alpha-beta T cell activation 2.659418e-8
GO:0051641 cellular localization 2.684927e-8
GO:0031032 actomyosin structure organization 2.790252e-8
GO:0050670 regulation of lymphocyte proliferation 2.816090e-8
GO:0006691 leukotriene metabolic process 2.868442e-8
GO:0009893 positive regulation of metabolic process 2.996494e-8
GO:0070663 regulation of leukocyte proliferation 3.093582e-8
GO:0032944 regulation of mononuclear cell proliferation 3.171233e-8
GO:0006917 induction of apoptosis 3.360289e-8
GO:0060341 regulation of cellular localization 3.618157e-8
GO:0030212 hyaluronan metabolic process 3.889382e-8
GO:0002696 positive regulation of leukocyte activation 4.946586e-8
GO:0002449 lymphocyte mediated immunity 4.972883e-8
GO:0007586 digestion 5.118455e-8
GO:0045058 T cell selection 5.354586e-8
GO:0014904 myotube cell development 5.776783e-8
GO:0014732 skeletal muscle atrophy 5.987126e-8
GO:0055006 cardiac cell development 6.444993e-8
GO:0051050 positive regulation of transport 6.686335e-8
GO:0008593 regulation of Notch signaling pathway 6.823346e-8
GO:0009725 response to hormone stimulus 7.213509e-8
GO:0042325 regulation of phosphorylation 8.357556e-8
GO:0032268 regulation of cellular protein metabolic process 8.556014e-8
GO:0007165 signal transduction 9.477975e-8
GO:0031325 positive regulation of cellular metabolic process 9.767455e-8
GO:0030104 water homeostasis 9.874873e-8
GO:0008610 lipid biosynthetic process 1.012634e-7
GO:0023061 signal release 1.044042e-7
GO:0019538 protein metabolic process 1.054880e-7
GO:0031667 response to nutrient levels 1.068247e-7
GO:0030855 epithelial cell differentiation 1.111033e-7
GO:0052547 regulation of peptidase activity 1.169311e-7
GO:0021537 telencephalon development 1.422980e-7
GO:0051145 smooth muscle cell differentiation 1.455840e-7
GO:0002694 regulation of leukocyte activation 1.495007e-7
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 1.506979e-7
GO:0010035 response to inorganic substance 1.517679e-7
GO:0033005 positive regulation of mast cell activation 1.589097e-7
GO:0051606 detection of stimulus 1.590432e-7
GO:0046879 hormone secretion 1.607330e-7
GO:0009991 response to extracellular stimulus 1.685946e-7
GO:0007600 sensory perception 1.981324e-7
GO:0050671 positive regulation of lymphocyte proliferation 2.009849e-7
GO:0051186 cofactor metabolic process 2.036238e-7
GO:0042180 cellular ketone metabolic process 2.064456e-7
GO:0000003 reproduction 2.085250e-7
GO:0030239 myofibril assembly 2.246569e-7
GO:0050867 positive regulation of cell activation 2.305081e-7
GO:0032946 positive regulation of mononuclear cell proliferation 2.305846e-7
GO:0046649 lymphocyte activation 2.306913e-7
GO:0010627 regulation of intracellular protein kinase cascade 2.517979e-7
GO:0046425 regulation of JAK-STAT cascade 2.552638e-7
GO:0055114 oxidation-reduction process 2.730215e-7
GO:0019752 carboxylic acid metabolic process 2.877864e-7
GO:0048534 hemopoietic or lymphoid organ development 2.905921e-7
GO:0002521 leukocyte differentiation 2.968395e-7
GO:0001654 eye development 2.971386e-7
GO:0048583 regulation of response to stimulus 3.091635e-7
GO:0006732 coenzyme metabolic process 3.404905e-7
GO:0070665 positive regulation of leukocyte proliferation 3.445040e-7
GO:0006520 cellular amino acid metabolic process 3.660436e-7
GO:0070848 response to growth factor stimulus 3.703259e-7
GO:0043306 positive regulation of mast cell degranulation 3.950441e-7
GO:0021761 limbic system development 3.980093e-7
GO:0009896 positive regulation of catabolic process 4.000623e-7
GO:0034498 early endosome to Golgi transport 4.218746e-7
GO:0002544 chronic inflammatory response 4.299479e-7
GO:0003012 muscle system process 4.338778e-7
GO:0048878 chemical homeostasis 4.375862e-7
GO:0060795 cell fate commitment involved in formation of primary germ layers 4.458794e-7
GO:0006790 sulfur compound metabolic process 4.461297e-7
GO:0042493 response to drug 5.154081e-7
GO:0002275 myeloid cell activation involved in immune response 5.711912e-7
GO:0001835 blastocyst hatching 5.999126e-7
GO:0045747 positive regulation of Notch signaling pathway 6.173841e-7
GO:0002520 immune system development 6.378566e-7
GO:0002439 chronic inflammatory response to antigenic stimulus 6.440462e-7
GO:0051043 regulation of membrane protein ectodomain proteolysis 6.577539e-7
GO:0050878 regulation of body fluid levels 6.587439e-7
GO:0046324 regulation of glucose import 6.707430e-7
GO:0055001 muscle cell development 6.880500e-7
GO:0051533 positive regulation of NFAT protein import into nucleus 7.245188e-7
GO:0008544 epidermis development 7.693914e-7
GO:0042035 regulation of cytokine biosynthetic process 8.269369e-7
GO:0043434 response to peptide hormone stimulus 8.416061e-7
GO:0008283 cell proliferation 9.625335e-7
GO:0022414 reproductive process 9.679477e-7
GO:0006629 lipid metabolic process 9.792001e-7
GO:0060548 negative regulation of cell death 9.837530e-7
GO:0003007 heart morphogenesis 9.973773e-7
GO:0006082 organic acid metabolic process 1.031327e-6
GO:0043954 cellular component maintenance 1.112751e-6
GO:0030003 cellular cation homeostasis 1.138945e-6
GO:0044283 small molecule biosynthetic process 1.210050e-6
GO:0043009 chordate embryonic development 1.239645e-6
GO:0042110 T cell activation 1.339690e-6
GO:0071705 nitrogen compound transport 1.510279e-6
GO:0043302 positive regulation of leukocyte degranulation 1.517614e-6
GO:0002253 activation of immune response 1.564674e-6
GO:0002456 T cell mediated immunity 1.576680e-6
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 1.590174e-6
GO:0071702 organic substance transport 1.702325e-6
GO:0042692 muscle cell differentiation 1.756572e-6
GO:0010941 regulation of cell death 1.779109e-6
GO:0010466 negative regulation of peptidase activity 1.830807e-6
GO:0043901 negative regulation of multi-organism process 1.846491e-6
GO:0065009 regulation of molecular function 1.853722e-6
GO:0045047 protein targeting to ER 1.856091e-6
GO:0021766 hippocampus development 1.881960e-6
GO:0050863 regulation of T cell activation 1.898797e-6
GO:0009792 embryo development ending in birth or egg hatching 1.939750e-6
GO:0043069 negative regulation of programmed cell death 1.957677e-6
GO:0009628 response to abiotic stimulus 1.958534e-6
GO:0030154 cell differentiation 1.961716e-6
GO:0044281 small molecule metabolic process 2.061628e-6
GO:0048519 negative regulation of biological process 2.122406e-6
GO:0023051 regulation of signaling 2.125158e-6
GO:0030097 hemopoiesis 2.127637e-6
GO:0051187 cofactor catabolic process 2.159401e-6
GO:0055013 cardiac muscle cell development 2.168847e-6
GO:0002682 regulation of immune system process 2.214852e-6
GO:0046633 alpha-beta T cell proliferation 2.251346e-6
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein 2.315718e-6
GO:0007423 sensory organ development 2.318799e-6
GO:0002366 leukocyte activation involved in immune response 2.354703e-6
GO:0009966 regulation of signal transduction 2.377887e-6
GO:0045821 positive regulation of glycolysis 2.541417e-6
GO:0006954 inflammatory response 2.573924e-6
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.713333e-6
GO:0043900 regulation of multi-organism process 2.837457e-6
GO:0014888 striated muscle adaptation 2.905143e-6
GO:0043067 regulation of programmed cell death 2.999516e-6
GO:0010837 regulation of keratinocyte proliferation 3.023127e-6
GO:0052548 regulation of endopeptidase activity 3.092559e-6
GO:0009653 anatomical structure morphogenesis 3.157873e-6
GO:0050865 regulation of cell activation 3.239090e-6
GO:0060741 prostate gland stromal morphogenesis 3.253075e-6
GO:0043366 beta selection 3.261360e-6
GO:0043066 negative regulation of apoptosis 3.322552e-6
GO:0055082 cellular chemical homeostasis 3.420687e-6
GO:0046942 carboxylic acid transport 3.457018e-6
GO:0051093 negative regulation of developmental process 3.505265e-6
GO:0043501 skeletal muscle adaptation 3.513179e-6
GO:0050790 regulation of catalytic activity 3.638547e-6
GO:0051251 positive regulation of lymphocyte activation 3.690023e-6
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 3.843023e-6
GO:0042473 outer ear morphogenesis 3.862899e-6
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 3.933035e-6
GO:0055080 cation homeostasis 3.940589e-6
GO:0007501 mesodermal cell fate specification 4.031893e-6
GO:0060850 regulation of transcription involved in cell fate commitment 4.125970e-6
GO:0002250 adaptive immune response 4.134961e-6
GO:0051239 regulation of multicellular organismal process 4.174007e-6
GO:0001666 response to hypoxia 4.281803e-6
GO:0034097 response to cytokine stimulus 4.321892e-6
GO:0045787 positive regulation of cell cycle 4.344467e-6
GO:0035556 intracellular signal transduction 4.408324e-6
GO:0002757 immune response-activating signal transduction 4.602640e-6
GO:0034392 negative regulation of smooth muscle cell apoptosis 4.621853e-6
GO:0042981 regulation of apoptosis 4.700546e-6
GO:0043304 regulation of mast cell degranulation 4.713974e-6
GO:0045184 establishment of protein localization 4.757689e-6
GO:0045062 extrathymic T cell selection 4.782193e-6
GO:0080134 regulation of response to stress 4.819737e-6
GO:0035630 bone mineralization involved in bone maturation 4.891086e-6
GO:0072594 establishment of protein localization to organelle 5.040111e-6
GO:0046640 regulation of alpha-beta T cell proliferation 5.299590e-6
GO:0000041 transition metal ion transport 5.369096e-6
GO:0050877 neurological system process 5.397677e-6
GO:0009891 positive regulation of biosynthetic process 5.443518e-6
GO:0015031 protein transport 5.581910e-6
GO:0031328 positive regulation of cellular biosynthetic process 5.825632e-6
GO:0034391 regulation of smooth muscle cell apoptosis 6.095036e-6
GO:0033006 regulation of mast cell activation involved in immune response 6.142626e-6
GO:0050654 chondroitin sulfate proteoglycan metabolic process 6.323090e-6
GO:0050789 regulation of biological process 6.476992e-6
GO:0050432 catecholamine secretion 6.694224e-6
GO:0048545 response to steroid hormone stimulus 6.730120e-6
GO:0002429 immune response-activating cell surface receptor signaling pathway 6.942437e-6
GO:0030900 forebrain development 7.158401e-6
GO:0033762 response to glucagon stimulus 7.290982e-6
GO:0045165 cell fate commitment 7.306658e-6
GO:0001714 endodermal cell fate specification 7.587354e-6
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development 8.173687e-6
GO:0006029 proteoglycan metabolic process 8.343638e-6
GO:0051046 regulation of secretion 8.380907e-6
GO:0042108 positive regulation of cytokine biosynthetic process 8.463795e-6
GO:0010646 regulation of cell communication 8.543300e-6
GO:0007492 endoderm development 8.797336e-6
GO:0031000 response to caffeine 8.990553e-6
GO:0045840 positive regulation of mitosis 9.259994e-6
GO:0042668 auditory receptor cell fate determination 9.857844e-6
GO:0048869 cellular developmental process 1.009114e-5
GO:0010557 positive regulation of macromolecule biosynthetic process 1.014824e-5
GO:0006084 acetyl-CoA metabolic process 1.023728e-5
GO:0032819 positive regulation of natural killer cell proliferation 1.036471e-5
GO:0018149 peptide cross-linking 1.043271e-5
GO:0001709 cell fate determination 1.056148e-5
GO:2000026 regulation of multicellular organismal development 1.060169e-5
GO:0010827 regulation of glucose transport 1.060453e-5
GO:0045471 response to ethanol 1.124479e-5
GO:0051707 response to other organism 1.126973e-5
GO:0071310 cellular response to organic substance 1.152698e-5
GO:0046456 icosanoid biosynthetic process 1.153004e-5
GO:0042176 regulation of protein catabolic process 1.163283e-5
GO:0032844 regulation of homeostatic process 1.181800e-5
GO:0044130 negative regulation of growth of symbiont in host 1.187773e-5
GO:0072358 cardiovascular system development 1.189542e-5
GO:0009913 epidermal cell differentiation 1.205141e-5
GO:0045494 photoreceptor cell maintenance 1.212718e-5
GO:0015849 organic acid transport 1.235486e-5
GO:0070977 bone maturation 1.249346e-5
GO:0035051 cardiac cell differentiation 1.267526e-5
GO:0051648 vesicle localization 1.288315e-5
GO:0006812 cation transport 1.316116e-5
GO:0033036 macromolecule localization 1.317424e-5
GO:0060037 pharyngeal system development 1.318015e-5
GO:0002577 regulation of antigen processing and presentation 1.342881e-5
GO:0048242 epinephrine secretion 1.387964e-5
GO:0043010 camera-type eye development 1.410362e-5
GO:0048562 embryonic organ morphogenesis 1.418908e-5
GO:0009109 coenzyme catabolic process 1.436991e-5
GO:0007006 mitochondrial membrane organization 1.451572e-5
GO:0045401 positive regulation of interleukin-3 biosynthetic process 1.461642e-5
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 1.461642e-5
GO:0045214 sarcomere organization 1.461896e-5
GO:0002819 regulation of adaptive immune response 1.492908e-5
GO:0006875 cellular metal ion homeostasis 1.509465e-5
GO:0006873 cellular ion homeostasis 1.513673e-5
GO:0043408 regulation of MAPKKK cascade 1.529354e-5
GO:0045338 farnesyl diphosphate metabolic process 1.599771e-5
GO:0009581 detection of external stimulus 1.627001e-5
GO:0015876 acetyl-CoA transport 1.639823e-5
GO:0051315 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 1.639823e-5
GO:0051249 regulation of lymphocyte activation 1.673431e-5
GO:0055065 metal ion homeostasis 1.697662e-5
GO:0070727 cellular macromolecule localization 1.703245e-5
GO:0055085 transmembrane transport 1.708955e-5
GO:0043368 positive T cell selection 1.710830e-5
GO:0032854 positive regulation of Rap GTPase activity 1.723515e-5
GO:0046326 positive regulation of glucose import 1.748588e-5
GO:0007584 response to nutrient 1.762477e-5
GO:0001892 embryonic placenta development 1.794164e-5
GO:0032878 regulation of establishment or maintenance of cell polarity 1.805163e-5
GO:0031214 biomineral tissue development 1.890085e-5
GO:0001890 placenta development 1.890305e-5
GO:0014889 muscle atrophy 1.908553e-5
GO:0034613 cellular protein localization 1.960238e-5
GO:0010838 positive regulation of keratinocyte proliferation 2.012110e-5
GO:0001711 endodermal cell fate commitment 2.013456e-5
GO:0002528 regulation of vascular permeability involved in acute inflammatory response 2.055623e-5
GO:0035295 tube development 2.066542e-5
GO:0070972 protein localization in endoplasmic reticulum 2.070382e-5
GO:0050853 B cell receptor signaling pathway 2.112520e-5
GO:0007605 sensory perception of sound 2.123985e-5
GO:0050793 regulation of developmental process 2.130137e-5
GO:0051094 positive regulation of developmental process 2.130635e-5
GO:0046632 alpha-beta T cell differentiation 2.179360e-5
GO:0010660 regulation of muscle cell apoptosis 2.234716e-5
GO:0090199 regulation of release of cytochrome c from mitochondria 2.305246e-5
GO:0048592 eye morphogenesis 2.307734e-5
GO:0061198 fungiform papilla formation 2.312424e-5
GO:0001866 NK T cell proliferation 2.325653e-5
GO:0031347 regulation of defense response 2.342426e-5
GO:0071902 positive regulation of protein serine/threonine kinase activity 2.349870e-5
GO:0008104 protein localization 2.459478e-5
GO:0050801 ion homeostasis 2.545897e-5
GO:0009636 response to toxin 2.547367e-5
GO:0050851 antigen receptor-mediated signaling pathway 2.568705e-5
GO:2000021 regulation of ion homeostasis 2.571594e-5
GO:0050954 sensory perception of mechanical stimulus 2.696649e-5
GO:0045786 negative regulation of cell cycle 2.698299e-5
GO:0006022 aminoglycan metabolic process 2.727518e-5
GO:0002768 immune response-regulating cell surface receptor signaling pathway 2.749374e-5
GO:0048729 tissue morphogenesis 2.777198e-5
GO:0006427 histidyl-tRNA aminoacylation 2.802903e-5
GO:0002674 negative regulation of acute inflammatory response 2.910749e-5
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 2.984898e-5
GO:0051924 regulation of calcium ion transport 2.992423e-5
GO:0045621 positive regulation of lymphocyte differentiation 3.063701e-5
GO:0002764 immune response-regulating signaling pathway 3.081157e-5
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 3.126239e-5
GO:0010832 negative regulation of myotube differentiation 3.126239e-5
GO:0007155 cell adhesion 3.201410e-5
GO:0007166 cell surface receptor linked signaling pathway 3.221712e-5
GO:0046356 acetyl-CoA catabolic process 3.265163e-5
GO:0033137 negative regulation of peptidyl-serine phosphorylation 3.287871e-5
GO:0061196 fungiform papilla development 3.290379e-5
GO:0006636 unsaturated fatty acid biosynthetic process 3.431057e-5
GO:0030001 metal ion transport 3.439584e-5
GO:0051705 behavioral interaction between organisms 3.448956e-5
GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 3.502473e-5
GO:0045087 innate immune response 3.531629e-5
GO:0097084 vascular smooth muscle cell development 3.532635e-5
GO:0009791 post-embryonic development 3.618391e-5
GO:0007417 central nervous system development 3.674242e-5
GO:0048523 negative regulation of cellular process 3.726613e-5
GO:0001704 formation of primary germ layer 3.733871e-5
GO:0044092 negative regulation of molecular function 3.887843e-5
GO:0043588 skin development 3.988150e-5
GO:0045861 negative regulation of proteolysis 4.091624e-5
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 4.163490e-5
GO:0010656 negative regulation of muscle cell apoptosis 4.186758e-5
GO:0010817 regulation of hormone levels 4.423941e-5
GO:0040007 growth 4.590034e-5
GO:0009064 glutamine family amino acid metabolic process 4.593901e-5
GO:0046684 response to pyrethroid 4.623535e-5
GO:0051030 snRNA transport 4.634645e-5
GO:0043299 leukocyte degranulation 4.700737e-5
GO:0010735 positive regulation of transcription via serum response element binding 4.773135e-5
GO:0015819 lysine transport 4.854190e-5
GO:0015822 ornithine transport 4.854190e-5
GO:0009098 leucine biosynthetic process 4.854190e-5
GO:0006550 isoleucine catabolic process 4.854190e-5
GO:0060347 heart trabecula formation 4.889090e-5
GO:0022610 biological adhesion 4.919421e-5
GO:0051240 positive regulation of multicellular organismal process 4.945422e-5
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 4.948460e-5
GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein 4.963870e-5
GO:0050680 negative regulation of epithelial cell proliferation 4.976809e-5
GO:0014896 muscle hypertrophy 5.000355e-5
GO:0045732 positive regulation of protein catabolic process 5.081048e-5
GO:0007608 sensory perception of smell 5.162219e-5
GO:0001701 in utero embryonic development 5.185710e-5
GO:0015938 coenzyme A catabolic process 5.223115e-5
GO:0008616 queuosine biosynthetic process 5.223115e-5
GO:0055003 cardiac myofibril assembly 5.307997e-5
GO:0048597 post-embryonic camera-type eye morphogenesis 5.356188e-5
GO:0045597 positive regulation of cell differentiation 5.409945e-5
GO:0043269 regulation of ion transport 5.419201e-5
GO:0071900 regulation of protein serine/threonine kinase activity 5.447704e-5
GO:2000980 regulation of inner ear receptor cell differentiation 5.495794e-5
GO:0001887 selenium compound metabolic process 5.528952e-5
GO:0002697 regulation of immune effector process 5.549811e-5
GO:0048563 post-embryonic organ morphogenesis 5.583867e-5
GO:0043931 ossification involved in bone maturation 5.614697e-5
GO:0043500 muscle adaptation 5.655498e-5
GO:0009309 amine biosynthetic process 5.669772e-5
GO:0009607 response to biotic stimulus 5.705376e-5
GO:0014075 response to amine stimulus 5.747153e-5
GO:0042471 ear morphogenesis 5.828204e-5
GO:0003205 cardiac chamber development 5.935662e-5
GO:0045055 regulated secretory pathway 6.109872e-5
GO:0048050 post-embryonic eye morphogenesis 6.391022e-5
GO:0033364 mast cell secretory granule organization 6.482013e-5
GO:0061048 negative regulation of branching involved in lung morphogenesis 6.583958e-5
GO:0045994 positive regulation of translational initiation by iron 6.583958e-5
GO:0002037 negative regulation of L-glutamate transport 6.583958e-5
GO:0034116 positive regulation of heterotypic cell-cell adhesion 6.583958e-5
GO:0001821 histamine secretion 6.647907e-5
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 6.691244e-5
GO:0060788 ectodermal placode formation 6.757781e-5
GO:0001708 cell fate specification 6.762093e-5
GO:0006695 cholesterol biosynthetic process 6.817622e-5
GO:0010522 regulation of calcium ion transport into cytosol 6.878850e-5
GO:0009886 post-embryonic morphogenesis 6.898276e-5
GO:0002821 positive regulation of adaptive immune response 6.979797e-5
GO:0010828 positive regulation of glucose transport 7.435851e-5
GO:0001817 regulation of cytokine production 7.492973e-5
GO:0060947 cardiac vascular smooth muscle cell differentiation 7.602590e-5
GO:0043065 positive regulation of apoptosis 7.643865e-5
GO:0055007 cardiac muscle cell differentiation 7.669006e-5
GO:0051726 regulation of cell cycle 7.669583e-5
GO:0043406 positive regulation of MAP kinase activity 7.673692e-5
GO:0030029 actin filament-based process 7.707498e-5
GO:0007601 visual perception 7.816540e-5
GO:0045073 regulation of chemokine biosynthetic process 7.892798e-5
GO:0021987 cerebral cortex development 7.941303e-5
GO:0042592 homeostatic process 7.974298e-5
GO:0030098 lymphocyte differentiation 8.097477e-5
GO:0070482 response to oxygen levels 8.111909e-5
GO:0050794 regulation of cellular process 8.247777e-5
GO:0044272 sulfur compound biosynthetic process 8.449790e-5
GO:0030203 glycosaminoglycan metabolic process 8.544259e-5
GO:0048660 regulation of smooth muscle cell proliferation 8.697011e-5
GO:0035987 endodermal cell differentiation 8.903367e-5
GO:0010927 cellular component assembly involved in morphogenesis 8.918994e-5
GO:0030217 T cell differentiation 9.151768e-5
GO:0015711 organic anion transport 9.274241e-5
GO:0015844 monoamine transport 9.311517e-5
GO:0042474 middle ear morphogenesis 9.311517e-5
GO:0010038 response to metal ion 9.326530e-5
GO:0050973 detection of mechanical stimulus involved in equilibrioception 9.337884e-5
GO:0043068 positive regulation of programmed cell death 9.383637e-5
GO:0007254 JNK cascade 9.479753e-5
GO:0008652 cellular amino acid biosynthetic process 9.538989e-5
GO:0009593 detection of chemical stimulus 9.715558e-5
GO:0035050 embryonic heart tube development 9.779142e-5
GO:0009749 response to glucose stimulus 9.806076e-5
GO:0072511 divalent inorganic cation transport 9.884844e-5
GO:0002339 B cell selection 9.905809e-5
GO:0030168 platelet activation 9.912839e-5
GO:0097150 neuronal stem cell maintenance 9.927539e-5
GO:0035887 aortic smooth muscle cell differentiation 9.927539e-5
GO:0060509 Type I pneumocyte differentiation 9.955722e-5
GO:0045080 positive regulation of chemokine biosynthetic process 9.955722e-5
GO:0060789 hair follicle placode formation 1.010464e-4
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1.011385e-4
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1.017972e-4
GO:0048863 stem cell differentiation 1.025648e-4
GO:0046907 intracellular transport 1.049711e-4
GO:0030036 actin cytoskeleton organization 1.067321e-4
GO:0042472 inner ear morphogenesis 1.067518e-4
GO:0001776 leukocyte homeostasis 1.069307e-4
GO:0009582 detection of abiotic stimulus 1.074537e-4
GO:0006612 protein targeting to membrane 1.083165e-4
GO:0001913 T cell mediated cytotoxicity 1.111927e-4
GO:0042063 gliogenesis 1.151929e-4
GO:0048598 embryonic morphogenesis 1.196580e-4
GO:0033273 response to vitamin 1.213768e-4