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Novel motif:40

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name:motif40_ATGCGGAGGAG

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0090192 regulation of glomerulus development 1.302533e-11
GO:0072124 regulation of glomerular mesangial cell proliferation 2.475004e-11
GO:0072298 regulation of metanephric glomerulus development 5.466977e-11
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 5.886295e-10
GO:0007522 visceral muscle development 2.749827e-8
GO:0072110 glomerular mesangial cell proliferation 9.082091e-8
GO:0097116 gephyrin clustering 1.526029e-7
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 4.383875e-7
GO:0097118 neuroligin clustering 5.139192e-7
GO:0071072 negative regulation of phospholipid biosynthetic process 5.203618e-7
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 5.314211e-7
GO:0072111 cell proliferation involved in kidney development 5.571552e-7
GO:0030157 pancreatic juice secretion 7.037974e-7
GO:0071071 regulation of phospholipid biosynthetic process 7.917654e-7
GO:0018277 protein deamination 8.171732e-7
GO:0097119 postsynaptic density protein 95 clustering 1.018371e-6
GO:0097104 postsynaptic membrane assembly 1.018371e-6
GO:0072126 positive regulation of glomerular mesangial cell proliferation 1.040327e-6
GO:0071506 cellular response to mycophenolic acid 1.040327e-6
GO:0033084 regulation of immature T cell proliferation in thymus 1.263754e-6
GO:0010624 regulation of Schwann cell proliferation 1.335047e-6
GO:0001662 behavioral fear response 2.864703e-6
GO:0006356 regulation of transcription from RNA polymerase I promoter 3.408324e-6
GO:0072125 negative regulation of glomerular mesangial cell proliferation 3.633294e-6
GO:0072109 glomerular mesangium development 3.633294e-6
GO:0090399 replicative senescence 3.740750e-6
GO:0042088 T-helper 1 type immune response 4.092504e-6
GO:0043084 penile erection 4.281342e-6
GO:0006449 regulation of translational termination 4.461284e-6
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 4.950771e-6
GO:0002209 behavioral defense response 5.915705e-6
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 5.979982e-6
GO:0043064 flagellum organization 6.904873e-6
GO:2000016 negative regulation of determination of dorsal identity 7.509501e-6
GO:0007288 sperm axoneme assembly 7.669265e-6
GO:0060251 regulation of glial cell proliferation 8.779819e-6
GO:0061003 positive regulation of dendritic spine morphogenesis 8.819624e-6
GO:0010511 regulation of phosphatidylinositol biosynthetic process 8.819624e-6
GO:0010225 response to UV-C 1.163635e-5
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 1.240904e-5
GO:0030509 BMP signaling pathway 1.375703e-5
GO:0071353 cellular response to interleukin-4 1.738534e-5
GO:0060999 positive regulation of dendritic spine development 1.865514e-5
GO:0055009 atrial cardiac muscle tissue morphogenesis 1.888788e-5
GO:0043586 tongue development 2.247974e-5
GO:0070861 regulation of protein exit from endoplasmic reticulum 2.249820e-5
GO:0021562 vestibulocochlear nerve development 2.770328e-5
GO:0035461 vitamin transmembrane transport 2.934937e-5
GO:0016574 histone ubiquitination 2.935478e-5
GO:0060005 vestibular reflex 2.952092e-5
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 3.158205e-5
GO:0071584 negative regulation of zinc ion import 3.207831e-5
GO:0090281 negative regulation of calcium ion import 3.207831e-5
GO:0071895 odontoblast differentiation 3.262737e-5
GO:0048332 mesoderm morphogenesis 3.288738e-5
GO:0070831 basement membrane assembly 3.376910e-5
GO:0035356 cellular triglyceride homeostasis 3.462916e-5
GO:0043923 positive regulation by host of viral transcription 3.571527e-5
GO:0048708 astrocyte differentiation 3.572778e-5
GO:0005983 starch catabolic process 3.575159e-5
GO:0019227 neuronal action potential propagation 3.848613e-5
GO:0032231 regulation of actin filament bundle assembly 4.011041e-5
GO:0042093 T-helper cell differentiation 4.292481e-5
GO:0002528 regulation of vascular permeability involved in acute inflammatory response 4.416516e-5
GO:0006398 histone mRNA 3'-end processing 4.599032e-5
GO:0045843 negative regulation of striated muscle tissue development 4.636150e-5
GO:0072179 nephric duct formation 5.054568e-5
GO:0090183 regulation of kidney development 5.274499e-5
GO:0008334 histone mRNA metabolic process 5.406141e-5
GO:0001707 mesoderm formation 5.454337e-5
GO:0042596 fear response 5.483816e-5
GO:0090128 regulation of synapse maturation 5.540344e-5
GO:0003406 retinal pigment epithelium development 5.848610e-5
GO:0090086 negative regulation of protein deubiquitination 6.550673e-5
GO:0072300 positive regulation of metanephric glomerulus development 6.684892e-5
GO:0071625 vocalization behavior 6.856483e-5
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 6.856483e-5
GO:0002309 T cell proliferation involved in immune response 6.954603e-5
GO:0043543 protein acylation 7.198600e-5
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 7.807077e-5
GO:0048752 semicircular canal morphogenesis 8.723499e-5
GO:0001886 endothelial cell morphogenesis 8.811918e-5
GO:0030828 positive regulation of cGMP biosynthetic process 8.896333e-5
GO:0033233 regulation of protein sumoylation 9.428629e-5
GO:0046814 virion attachment, binding of host cell surface coreceptor 9.770113e-5
GO:0060923 cardiac muscle cell fate commitment 1.049939e-4
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity 1.143964e-4
GO:0008292 acetylcholine biosynthetic process 1.179974e-4
GO:0017145 stem cell division 1.218644e-4
GO:0000956 nuclear-transcribed mRNA catabolic process 1.288917e-4
GO:0055107 Golgi to secretory granule transport 1.366099e-4
GO:2000370 positive regulation of clathrin-mediated endocytosis 1.398542e-4
GO:0014739 positive regulation of muscle hyperplasia 1.398542e-4
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1.577174e-4
GO:0043503 skeletal muscle fiber adaptation 1.737929e-4
GO:0006473 protein acetylation 1.742581e-4
GO:0010835 regulation of protein ADP-ribosylation 1.779746e-4
GO:0030223 neutrophil differentiation 1.904540e-4
GO:0032793 positive regulation of CREB transcription factor activity 1.982685e-4
GO:0006335 DNA replication-dependent nucleosome assembly 2.035334e-4
GO:0033092 positive regulation of immature T cell proliferation in thymus 2.096310e-4
GO:0061153 trachea gland development 2.106228e-4
GO:0070079 histone H4-R3 demethylation 2.159947e-4
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 2.159947e-4
GO:0070078 histone H3-R2 demethylation 2.159947e-4
GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter 2.159947e-4
GO:0071934 thiamine transmembrane transport 2.186051e-4
GO:0034766 negative regulation of ion transmembrane transport 2.186051e-4
GO:0003329 pancreatic PP cell fate commitment 2.305044e-4
GO:0003326 pancreatic A cell fate commitment 2.305044e-4
GO:0006513 protein monoubiquitination 2.334914e-4
GO:0071866 negative regulation of apoptosis in bone marrow 2.416458e-4
GO:0071864 positive regulation of cell proliferation in bone marrow 2.416458e-4
GO:0060710 chorio-allantoic fusion 2.557586e-4
GO:0045662 negative regulation of myoblast differentiation 2.584833e-4
GO:0006562 proline catabolic process 2.609222e-4
GO:2000573 positive regulation of DNA biosynthetic process 2.797593e-4
GO:0042593 glucose homeostasis 2.807288e-4
GO:0003180 aortic valve morphogenesis 2.948459e-4
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 3.029322e-4
GO:0033490 cholesterol biosynthetic process via lathosterol 3.029322e-4
GO:0043462 regulation of ATPase activity 3.039442e-4
GO:0061032 visceral serous pericardium development 3.091870e-4
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 3.091870e-4
GO:2000597 positive regulation of optic nerve formation 3.091870e-4
GO:0061360 optic chiasma development 3.091870e-4
GO:0006173 dADP biosynthetic process 3.091870e-4
GO:0021633 optic nerve structural organization 3.091870e-4
GO:0021650 vestibulocochlear nerve formation 3.091870e-4
GO:0035799 ureter maturation 3.091870e-4
GO:0032656 regulation of interleukin-13 production 3.109006e-4
GO:0019064 viral envelope fusion with host membrane 3.377556e-4
GO:0035566 regulation of metanephros size 3.631237e-4
GO:0014807 regulation of somitogenesis 3.631237e-4
GO:0071539 protein localization to centrosome 3.632372e-4
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.632372e-4
GO:0072215 regulation of metanephros development 3.653160e-4
GO:0050434 positive regulation of viral transcription 3.740821e-4
GO:0016180 snRNA processing 3.750919e-4
GO:0045657 positive regulation of monocyte differentiation 3.789750e-4
GO:0016073 snRNA metabolic process 4.007521e-4
GO:0033083 regulation of immature T cell proliferation 4.040570e-4
GO:0051315 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 4.055653e-4
GO:0010626 negative regulation of Schwann cell proliferation 4.637630e-4
GO:0048103 somatic stem cell division 4.639385e-4
GO:0060816 random inactivation of X chromosome 4.641753e-4
GO:0061113 pancreas morphogenesis 4.641753e-4
GO:0061157 mRNA destabilization 4.700238e-4
GO:0045090 retroviral genome replication 4.700238e-4
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 4.700238e-4
GO:0045063 T-helper 1 cell differentiation 4.714218e-4
GO:0001941 postsynaptic membrane organization 4.938947e-4
GO:0035518 histone H2A monoubiquitination 5.035574e-4
GO:0007625 grooming behavior 5.128823e-4
GO:0097117 guanylate kinase-associated protein clustering 5.237476e-4
GO:0097114 N-methyl-D-aspartate receptor clustering 5.237476e-4
GO:0097112 gamma-aminobutyric acid receptor clustering 5.237476e-4
GO:0010719 negative regulation of epithelial to mesenchymal transition 5.287308e-4
GO:0021943 formation of radial glial scaffolds 5.322483e-4
GO:0033522 histone H2A ubiquitination 5.399053e-4
GO:0042450 arginine biosynthetic process via ornithine 5.707337e-4
GO:0010625 positive regulation of Schwann cell proliferation 5.869507e-4
GO:0050872 white fat cell differentiation 6.251007e-4
GO:0033602 negative regulation of dopamine secretion 6.592049e-4
GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing 6.592049e-4
GO:0007259 JAK-STAT cascade 6.686222e-4
GO:0032856 activation of Ras GTPase activity 6.722154e-4
GO:0060253 negative regulation of glial cell proliferation 6.747876e-4
GO:0090129 positive regulation of synapse maturation 6.986124e-4
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 7.016784e-4
GO:0060020 Bergmann glial cell differentiation 7.201476e-4
GO:0034723 DNA replication-dependent nucleosome organization 7.464812e-4
GO:0060242 contact inhibition 7.464812e-4
GO:0032926 negative regulation of activin receptor signaling pathway 7.697205e-4
GO:0060252 positive regulation of glial cell proliferation 8.111393e-4
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 8.151819e-4
GO:2000143 negative regulation of transcription initiation, DNA-dependent 8.353957e-4
GO:0019086 late viral mRNA transcription 8.353957e-4
GO:0060547 negative regulation of necrotic cell death 8.386187e-4
GO:0002051 osteoblast fate commitment 8.408720e-4
GO:0060561 apoptosis involved in morphogenesis 8.498757e-4
GO:0032674 regulation of interleukin-5 production 8.515350e-4
GO:0071504 cellular response to heparin 8.673378e-4
GO:0015809 arginine transport 9.143777e-4
GO:0042506 tyrosine phosphorylation of Stat5 protein 9.308785e-4
GO:0001823 mesonephros development 9.363386e-4
GO:0001974 blood vessel remodeling 9.756093e-4
GO:0097120 receptor localization to synapse 9.982535e-4
GO:0072578 neurotransmitter-gated ion channel clustering 9.982535e-4
GO:0006538 glutamate catabolic process 1.001753e-3
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1.046168e-3
GO:0043313 regulation of neutrophil degranulation 1.048446e-3
GO:0070863 positive regulation of protein exit from endoplasmic reticulum 1.050432e-3
GO:0031063 regulation of histone deacetylation 1.064279e-3
GO:0009296 flagellum assembly 1.085352e-3
GO:0014053 negative regulation of gamma-aminobutyric acid secretion 1.093807e-3
GO:0010529 negative regulation of transposition 1.127764e-3
GO:0046532 regulation of photoreceptor cell differentiation 1.136964e-3
GO:0032092 positive regulation of protein binding 1.142044e-3
GO:0035418 protein localization to synapse 1.150247e-3
GO:0070574 cadmium ion transmembrane transport 1.159677e-3
GO:0030851 granulocyte differentiation 1.170333e-3
GO:0006475 internal protein amino acid acetylation 1.176654e-3
GO:0048168 regulation of neuronal synaptic plasticity 1.197469e-3
GO:0046533 negative regulation of photoreceptor cell differentiation 1.219956e-3
GO:0030382 sperm mitochondrion organization 1.232466e-3
GO:0051586 positive regulation of dopamine uptake 1.265007e-3
GO:0048210 Golgi vesicle fusion to target membrane 1.265007e-3
GO:0070105 positive regulation of interleukin-6-mediated signaling pathway 1.269399e-3
GO:0003062 regulation of heart rate by chemical signal 1.292845e-3
GO:0043314 negative regulation of neutrophil degranulation 1.321230e-3
GO:0033088 negative regulation of immature T cell proliferation in thymus 1.360451e-3
GO:0097105 presynaptic membrane assembly 1.375768e-3
GO:0032862 activation of Rho GTPase activity 1.457884e-3
GO:0051497 negative regulation of stress fiber assembly 1.486599e-3
GO:0048635 negative regulation of muscle organ development 1.488738e-3
GO:0034389 lipid particle organization 1.566864e-3
GO:0006268 DNA unwinding involved in replication 1.649101e-3
GO:0009189 deoxyribonucleoside diphosphate biosynthetic process 1.651775e-3
GO:0071585 detoxification of cadmium ion 1.672618e-3
GO:0048341 paraxial mesoderm formation 1.762535e-3
GO:0044258 intestinal lipid catabolic process 1.812468e-3
GO:0018350 protein esterification 1.812468e-3
GO:0009436 glyoxylate catabolic process 1.863372e-3
GO:0018364 peptidyl-glutamine methylation 1.863372e-3
GO:0003310 pancreatic A cell differentiation 1.894523e-3
GO:0072203 cell proliferation involved in metanephros development 1.896588e-3
GO:0030852 regulation of granulocyte differentiation 1.897906e-3
GO:0009299 mRNA transcription 1.923540e-3
GO:0060370 susceptibility to T cell mediated cytotoxicity 1.961365e-3
GO:0071503 response to heparin 2.002639e-3
GO:0045838 positive regulation of membrane potential 2.028364e-3
GO:0009186 deoxyribonucleoside diphosphate metabolic process 2.043034e-3
GO:0072178 nephric duct morphogenesis 2.067863e-3
GO:0019428 allantoin biosynthetic process 2.078544e-3
GO:0072176 nephric duct development 2.140381e-3
GO:0072498 embryonic skeletal joint development 2.216727e-3
GO:0051102 DNA ligation involved in DNA recombination 2.285060e-3
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 2.304613e-3
GO:0090193 positive regulation of glomerulus development 2.304613e-3
GO:0045342 MHC class II biosynthetic process 2.336491e-3
GO:0070839 divalent metal ion export 2.336491e-3
GO:0006876 cellular cadmium ion homeostasis 2.336491e-3
GO:0043091 L-arginine import 2.336491e-3
GO:0032632 interleukin-3 production 2.336491e-3
GO:0015707 nitrite transport 2.336491e-3
GO:0006537 glutamate biosynthetic process 2.347959e-3
GO:0018205 peptidyl-lysine modification 2.409967e-3
GO:0000710 meiotic mismatch repair 2.415700e-3
GO:0043367 CD4-positive, alpha-beta T cell differentiation 2.429072e-3
GO:0072075 metanephric mesenchyme development 2.442487e-3
GO:0051492 regulation of stress fiber assembly 2.480648e-3
GO:0030422 production of siRNA involved in RNA interference 2.513618e-3
GO:0050652 dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 2.563003e-3
GO:0006408 snRNA export from nucleus 2.563003e-3
GO:0090311 regulation of protein deacetylation 2.620200e-3
GO:0007064 mitotic sister chromatid cohesion 2.659605e-3
GO:0014733 regulation of skeletal muscle adaptation 2.681639e-3
GO:0030853 negative regulation of granulocyte differentiation 2.696893e-3
GO:0001710 mesodermal cell fate commitment 2.735026e-3
GO:0046341 CDP-diacylglycerol metabolic process 2.852182e-3
GO:0090278 negative regulation of peptide hormone secretion 2.904743e-3
GO:0007221 positive regulation of transcription of Notch receptor target 2.926514e-3
GO:0006654 phosphatidic acid biosynthetic process 2.930173e-3
GO:0000115 regulation of transcription involved in S phase of mitotic cell cycle 2.944799e-3
GO:0071394 cellular response to testosterone stimulus 2.986137e-3
GO:0044356 clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine 3.005626e-3
GO:0060591 chondroblast differentiation 3.005721e-3
GO:0009084 glutamine family amino acid biosynthetic process 3.040491e-3
GO:0043268 positive regulation of potassium ion transport 3.077274e-3
GO:0021703 locus ceruleus development 3.099243e-3
GO:0006424 glutamyl-tRNA aminoacylation 3.099243e-3
GO:0010717 regulation of epithelial to mesenchymal transition 3.136981e-3
GO:0032233 positive regulation of actin filament bundle assembly 3.142503e-3
GO:0014037 Schwann cell differentiation 3.161350e-3
GO:0016573 histone acetylation 3.254275e-3
GO:0046473 phosphatidic acid metabolic process 3.254747e-3
GO:0050885 neuromuscular process controlling balance 3.278507e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 3.314255e-3
GO:0051318 G1 phase 3.336546e-3
GO:0030262 apoptotic nuclear change 3.403263e-3
GO:0090400 stress-induced premature senescence 3.497736e-3
GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose 3.619071e-3
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 3.684431e-3
GO:0048733 sebaceous gland development 3.768045e-3
GO:0033081 regulation of T cell differentiation in thymus 3.851911e-3
GO:0051645 Golgi localization 3.903989e-3
GO:0045575 basophil activation 3.903989e-3
GO:0001694 histamine biosynthetic process 3.903989e-3
GO:0006431 methionyl-tRNA aminoacylation 3.936011e-3
GO:0002642 positive regulation of immunoglobulin biosynthetic process 3.936011e-3
GO:0018394 peptidyl-lysine acetylation 3.948908e-3
GO:0007080 mitotic metaphase plate congression 3.957585e-3
GO:0060684 epithelial-mesenchymal cell signaling 4.021976e-3
GO:0010390 histone monoubiquitination 4.034933e-3
GO:0002293 alpha-beta T cell differentiation involved in immune response 4.052673e-3
GO:0018393 internal peptidyl-lysine acetylation 4.068139e-3
GO:0002268 follicular dendritic cell differentiation 4.087137e-3
GO:0006172 ADP biosynthetic process 4.133641e-3
GO:0014044 Schwann cell development 4.185426e-3
GO:0021535 cell migration in hindbrain 4.225344e-3
GO:0031064 negative regulation of histone deacetylation 4.234625e-3
GO:0045655 regulation of monocyte differentiation 4.299610e-3
GO:0009153 purine deoxyribonucleotide biosynthetic process 4.308957e-3
GO:0051103 DNA ligation involved in DNA repair 4.446229e-3
GO:0043243 positive regulation of protein complex disassembly 4.494797e-3
GO:0043276 anoikis 4.497584e-3
GO:2000195 negative regulation of female gonad development 4.526033e-3
GO:0060123 regulation of growth hormone secretion 4.528627e-3
GO:0072537 fibroblast activation 4.567811e-3
GO:0003094 glomerular filtration 4.567811e-3
GO:0044342 type B pancreatic cell proliferation 4.610557e-3
GO:0010918 positive regulation of mitochondrial membrane potential 4.610557e-3
GO:0035883 enteroendocrine cell differentiation 4.610557e-3
GO:0035710 CD4-positive, alpha-beta T cell activation 4.616615e-3
GO:0030844 positive regulation of intermediate filament depolymerization 4.618349e-3
GO:0052565 response to defense-related host nitric oxide production 4.618349e-3
GO:0022011 myelination in peripheral nervous system 4.674042e-3
GO:0032696 negative regulation of interleukin-13 production 4.696515e-3
GO:0046676 negative regulation of insulin secretion 4.731551e-3
GO:0090141 positive regulation of mitochondrial fission 4.739046e-3
GO:0000255 allantoin metabolic process 4.792655e-3
GO:0045217 cell-cell junction maintenance 4.799443e-3
GO:0003416 endochondral bone growth 5.004237e-3
GO:0050775 positive regulation of dendrite morphogenesis 5.073155e-3
GO:0071955 recycling endosome to Golgi transport 5.139710e-3
GO:0034499 late endosome to Golgi transport 5.139710e-3
GO:0010735 positive regulation of transcription via serum response element binding 5.188677e-3
GO:0045618 positive regulation of keratinocyte differentiation 5.215149e-3
GO:0007621 negative regulation of female receptivity 5.215149e-3
GO:0071557 histone H3-K27 demethylation 5.313797e-3
GO:0035574 histone H4-K20 demethylation 5.313797e-3
GO:0003417 growth plate cartilage development 5.325155e-3
GO:0048069 eye pigmentation 5.410907e-3
GO:2000194 regulation of female gonad development 5.442636e-3
GO:0050748 negative regulation of lipoprotein metabolic process 5.442636e-3
GO:0007501 mesodermal cell fate specification 5.489727e-3
GO:2000272 negative regulation of receptor activity 5.511091e-3
GO:0072134 nephrogenic mesenchyme morphogenesis 5.648263e-3
GO:0002021 response to dietary excess 5.671288e-3
GO:0055026 negative regulation of cardiac muscle tissue development 5.715654e-3
GO:0031643 positive regulation of myelination 5.715654e-3
GO:0042723 thiamine-containing compound metabolic process 5.744665e-3
GO:0060351 cartilage development involved in endochondral bone morphogenesis 5.782911e-3
GO:0072095 regulation of branch elongation involved in ureteric bud branching 5.997758e-3
GO:0032796 uropod organization 6.030842e-3
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 6.102296e-3
GO:0015747 urate transport 6.102296e-3
GO:0045078 positive regulation of interferon-gamma biosynthetic process 6.275305e-3
GO:0051081 nuclear envelope disassembly 6.340749e-3
GO:0006363 termination of RNA polymerase I transcription 6.364106e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 6.547252e-3
GO:2000463 positive regulation of excitatory postsynaptic membrane potential 6.567666e-3
GO:0042780 tRNA 3'-end processing 6.570877e-3
GO:0031118 rRNA pseudouridine synthesis 6.570877e-3
GO:0051793 medium-chain fatty acid catabolic process 6.570877e-3
GO:0010571 positive regulation of DNA replication involved in S phase 6.570877e-3
GO:0019068 virion assembly 6.570877e-3
GO:0009065 glutamine family amino acid catabolic process 6.588716e-3
GO:2000369 regulation of clathrin-mediated endocytosis 6.658258e-3
GO:0008291 acetylcholine metabolic process 6.677592e-3
GO:0030224 monocyte differentiation 6.700670e-3
GO:0032714 negative regulation of interleukin-5 production 6.730148e-3
GO:0006361 transcription initiation from RNA polymerase I promoter 6.772625e-3
GO:0021932 hindbrain radial glia guided cell migration 6.793727e-3
GO:0060465 pharynx development 6.850650e-3
GO:0043990 histone H2A-S1 phosphorylation 6.850650e-3
GO:0034378 chylomicron assembly 6.850650e-3
GO:0035048 splicing factor protein import into nucleus 6.850650e-3
GO:0048050 post-embryonic eye morphogenesis 6.884026e-3
GO:0035417 negative regulation of mitotic prometaphase 6.884026e-3
GO:0003017 lymph circulation 7.012582e-3
GO:0055010 ventricular cardiac muscle tissue morphogenesis 7.099072e-3
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 7.118886e-3
GO:0060272 embryonic skeletal joint morphogenesis 7.147785e-3
GO:0035082 axoneme assembly 7.265085e-3
GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development 7.290728e-3
GO:0042989 sequestering of actin monomers 7.379067e-3
GO:0030037 actin filament reorganization involved in cell cycle 7.473363e-3
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 7.528959e-3
GO:0097090 presynaptic membrane organization 7.761125e-3
GO:0032108 negative regulation of response to nutrient levels 7.761125e-3
GO:0090161 Golgi ribbon formation 7.892124e-3
GO:0046349 amino sugar biosynthetic process 7.892124e-3
GO:0030220 platelet formation 8.013165e-3
GO:0060124 positive regulation of growth hormone secretion 8.086508e-3
GO:0006491 N-glycan processing 8.219190e-3
GO:0010159 specification of organ position 8.256448e-3
GO:0002086 diaphragm contraction 8.351428e-3
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 8.460586e-3
GO:0010034 response to acetate 8.465482e-3
GO:0070327 thyroid hormone transport 8.504408e-3
GO:0006379 mRNA cleavage 8.645547e-3
GO:0060070 canonical Wnt receptor signaling pathway 8.865042e-3
GO:0060847 endothelial cell fate specification 8.916203e-3
GO:0060220 camera-type eye photoreceptor cell fate commitment 8.916203e-3
GO:0043111 replication fork arrest 8.916203e-3
GO:0048074 negative regulation of eye pigmentation 8.916203e-3
GO:0035814 negative regulation of renal sodium excretion 8.978761e-3
GO:0090084 negative regulation of inclusion body assembly 8.995152e-3
GO:0046782 regulation of viral transcription 9.047334e-3
GO:0060376 positive regulation of mast cell differentiation 9.212880e-3
GO:0015884 folic acid transport 9.233405e-3
GO:0071732 cellular response to nitric oxide 9.233405e-3
GO:0060375 regulation of mast cell differentiation 9.314637e-3
GO:0046684 response to pyrethroid 9.314637e-3
GO:0019344 cysteine biosynthetic process 9.314637e-3
GO:0046604 positive regulation of mitotic centrosome separation 9.341902e-3
GO:0000379 tRNA-type intron splice site recognition and cleavage 9.341902e-3
GO:0006353 transcription termination, DNA-dependent 9.495381e-3
GO:0051095 regulation of helicase activity 9.495548e-3
GO:0048194 Golgi vesicle budding 9.623803e-3
GO:0045064 T-helper 2 cell differentiation 9.640483e-3
GO:0070383 DNA cytosine deamination 9.640483e-3
GO:0002315 marginal zone B cell differentiation 9.640483e-3
GO:0030073 insulin secretion 9.655522e-3
GO:0006622 protein targeting to lysosome 9.764266e-3
GO:0030825 positive regulation of cGMP metabolic process 9.902684e-3
GO:0060262 negative regulation of N-terminal protein palmitoylation 9.931340e-3
GO:0021547 midbrain-hindbrain boundary initiation 9.931340e-3
GO:0021501 prechordal plate formation 9.931340e-3
GO:0043949 regulation of cAMP-mediated signaling 9.952702e-3
GO:0000027 ribosomal large subunit assembly 1.000080e-2
GO:0016584 nucleosome positioning 1.039515e-2
GO:0060708 spongiotrophoblast differentiation 1.044299e-2
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 1.056284e-2
GO:0070194 synaptonemal complex disassembly 1.056284e-2
GO:2001044 regulation of integrin-mediated signaling pathway 1.070065e-2
GO:0042376 phylloquinone catabolic process 1.070065e-2
GO:0016191 synaptic vesicle uncoating 1.070065e-2
GO:0006741 NADP biosynthetic process 1.070065e-2
GO:0071899 negative regulation of estrogen receptor binding 1.070073e-2
GO:0043501 skeletal muscle adaptation 1.080406e-2
GO:0071472 cellular response to salt stress 1.083910e-2
GO:0000733 DNA strand renaturation 1.083910e-2
GO:0032232 negative regulation of actin filament bundle assembly 1.087839e-2
GO:0043570 maintenance of DNA repeat elements 1.093591e-2
GO:0043616 keratinocyte proliferation 1.095286e-2
GO:0051580 regulation of neurotransmitter uptake 1.095726e-2
GO:0021540 corpus callosum morphogenesis 1.101446e-2
GO:0051660 establishment of centrosome localization 1.101446e-2
GO:0060711 labyrinthine layer development 1.111121e-2
GO:0043966 histone H3 acetylation 1.112758e-2
GO:0035378 carbon dioxide transmembrane transport 1.113830e-2
GO:0043418 homocysteine catabolic process 1.113830e-2
GO:0035377 transepithelial water transport 1.113830e-2
GO:0085018 maintenance of symbiont-containing vacuole via substance secreted by host 1.113830e-2
GO:0019343 cysteine biosynthetic process via cystathionine 1.113830e-2
GO:0030950 establishment or maintenance of actin cytoskeleton polarity 1.113830e-2
GO:0006535 cysteine biosynthetic process from serine 1.113830e-2
GO:0019346 transsulfuration 1.113830e-2
GO:0006382 adenosine to inosine editing 1.152335e-2
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.159593e-2
GO:0001569 patterning of blood vessels 1.160161e-2
GO:0060350 endochondral bone morphogenesis 1.165303e-2
GO:0051279 regulation of release of sequestered calcium ion into cytosol 1.182562e-2
GO:0014015 positive regulation of gliogenesis 1.202263e-2
GO:0090403 oxidative stress-induced premature senescence 1.217438e-2
GO:0090085 regulation of protein deubiquitination 1.217438e-2
GO:0050847 progesterone receptor signaling pathway 1.220651e-2
GO:0023041 neuronal signal transduction 1.224246e-2
GO:0060023 soft palate development 1.224422e-2
GO:0055089 fatty acid homeostasis 1.227887e-2
GO:0006105 succinate metabolic process 1.238138e-2
GO:0070092 regulation of glucagon secretion 1.238423e-2
GO:0006402 mRNA catabolic process 1.254850e-2
GO:0030826 regulation of cGMP biosynthetic process 1.258545e-2
GO:0009133 nucleoside diphosphate biosynthetic process 1.265357e-2
GO:0043585 nose morphogenesis 1.265357e-2
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 1.268427e-2
GO:0061099 negative regulation of protein tyrosine kinase activity 1.322656e-2
GO:0032956 regulation of actin cytoskeleton organization 1.322776e-2
GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity 1.328903e-2
GO:0006657 CDP-choline pathway 1.328903e-2
GO:0097091 synaptic vesicle clustering 1.337062e-2
GO:0045606 positive regulation of epidermal cell differentiation 1.338801e-2
GO:0071480 cellular response to gamma radiation 1.359347e-2
GO:0071956 cellular component maintenance at cellular level 1.369300e-2
GO:0070670 response to interleukin-4 1.370831e-2
GO:0060349 bone morphogenesis 1.372045e-2
GO:0006298 mismatch repair 1.379537e-2
GO:0060713 labyrinthine layer morphogenesis 1.383820e-2
GO:0043587 tongue morphogenesis 1.385778e-2
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 1.386338e-2
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 1.387819e-2
GO:0048240 sperm capacitation 1.388936e-2
GO:0060580 ventral spinal cord interneuron fate determination 1.391609e-2
GO:0003327 type B pancreatic cell fate commitment 1.391609e-2
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.407752e-2
GO:0051099 positive regulation of binding 1.417200e-2
GO:0045616 regulation of keratinocyte differentiation 1.427834e-2
GO:0006891 intra-Golgi vesicle-mediated transport 1.437509e-2
GO:0006797 polyphosphate metabolic process 1.441672e-2
GO:0015919 peroxisomal membrane transport 1.441672e-2
GO:0042503 tyrosine phosphorylation of Stat3 protein 1.443211e-2
GO:0031532 actin cytoskeleton reorganization 1.444956e-2
GO:2000108 positive regulation of leukocyte apoptosis 1.448027e-2
GO:0007549 dosage compensation 1.458985e-2
GO:0006560 proline metabolic process 1.476144e-2
GO:0071205 protein localization to juxtaparanode region of axon 1.486823e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0016579 protein deubiquitination 1.112782e-37
GO:0070646 protein modification by small protein removal 8.678876e-34
GO:0070647 protein modification by small protein conjugation or removal 1.790465e-16
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 4.487770e-11
GO:0051865 protein autoubiquitination 1.419322e-10
GO:0034442 regulation of lipoprotein oxidation 2.646448e-10
GO:0050748 negative regulation of lipoprotein metabolic process 5.907652e-9
GO:0033344 cholesterol efflux 4.023425e-8
GO:0046032 ADP catabolic process 1.062568e-7
GO:0046709 IDP catabolic process 1.062568e-7
GO:0050746 regulation of lipoprotein metabolic process 1.321818e-7
GO:0070193 synaptonemal complex organization 1.376354e-7
GO:0010896 regulation of triglyceride catabolic process 1.430183e-7
GO:0021797 forebrain anterior/posterior pattern specification 1.661094e-7
GO:0050994 regulation of lipid catabolic process 2.938952e-7
GO:0018279 protein N-linked glycosylation via asparagine 3.797668e-7
GO:0001887 selenium compound metabolic process 4.953901e-7
GO:0046929 negative regulation of neurotransmitter secretion 1.127217e-6
GO:0046031 ADP metabolic process 1.410338e-6
GO:0072166 posterior mesonephric tubule development 1.549297e-6
GO:0007129 synapsis 1.995260e-6
GO:0070192 chromosome organization involved in meiosis 2.144463e-6
GO:0031133 regulation of axon diameter 2.824929e-6
GO:0042304 regulation of fatty acid biosynthetic process 3.462650e-6
GO:0010898 positive regulation of triglyceride catabolic process 4.112847e-6
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 4.333208e-6
GO:0016082 synaptic vesicle priming 4.350637e-6
GO:0043932 ossification involved in bone remodeling 5.754325e-6
GO:0046628 positive regulation of insulin receptor signaling pathway 7.074438e-6
GO:0032536 regulation of cell projection size 7.288839e-6
GO:0002036 regulation of L-glutamate transport 7.477210e-6
GO:0006601 creatine biosynthetic process 8.103935e-6
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 8.799893e-6
GO:0006982 response to lipid hydroperoxide 1.032615e-5
GO:0060674 placenta blood vessel development 1.176178e-5
GO:0006342 chromatin silencing 1.212223e-5
GO:2001076 positive regulation of metanephric ureteric bud development 1.332516e-5
GO:0007356 thorax and anterior abdomen determination 1.332516e-5
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 1.332516e-5
GO:0008616 queuosine biosynthetic process 1.445581e-5
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.735640e-5
GO:0051026 chiasma assembly 1.737120e-5
GO:0032849 positive regulation of cellular pH reduction 1.795044e-5
GO:0065005 protein-lipid complex assembly 1.798932e-5
GO:0006344 maintenance of chromatin silencing 1.820822e-5
GO:0045046 protein import into peroxisome membrane 1.837551e-5
GO:0006188 IMP biosynthetic process 2.804581e-5
GO:0007130 synaptonemal complex assembly 2.880048e-5
GO:0090177 establishment of planar polarity involved in neural tube closure 2.917096e-5
GO:0021516 dorsal spinal cord development 3.231625e-5
GO:0035021 negative regulation of Rac protein signal transduction 4.164515e-5
GO:0007354 zygotic determination of anterior/posterior axis, embryo 4.264503e-5
GO:0090140 regulation of mitochondrial fission 4.425364e-5
GO:0008617 guanosine metabolic process 4.425364e-5
GO:0050995 negative regulation of lipid catabolic process 4.681392e-5
GO:0033127 regulation of histone phosphorylation 4.754345e-5
GO:0045922 negative regulation of fatty acid metabolic process 5.120147e-5
GO:0090083 regulation of inclusion body assembly 5.385473e-5
GO:0021528 commissural neuron differentiation in spinal cord 5.983626e-5
GO:0021965 spinal cord ventral commissure morphogenesis 6.697514e-5
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 6.850525e-5
GO:0009088 threonine biosynthetic process 7.156957e-5
GO:0032648 regulation of interferon-beta production 7.676113e-5
GO:0051168 nuclear export 8.549030e-5
GO:0006189 'de novo' IMP biosynthetic process 9.064636e-5
GO:0006290 pyrimidine dimer repair 9.401064e-5
GO:0060716 labyrinthine layer blood vessel development 1.027075e-4
GO:0051004 regulation of lipoprotein lipase activity 1.055663e-4
GO:0032312 regulation of ARF GTPase activity 1.090303e-4
GO:0070265 necrotic cell death 1.096859e-4
GO:0045109 intermediate filament organization 1.146153e-4
GO:0042249 establishment of planar polarity of embryonic epithelium 1.221345e-4
GO:0008088 axon cargo transport 1.253955e-4
GO:0045787 positive regulation of cell cycle 1.271306e-4
GO:0090141 positive regulation of mitochondrial fission 1.430463e-4
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.461773e-4
GO:0002701 negative regulation of production of molecular mediator of immune response 1.556138e-4
GO:0002227 innate immune response in mucosa 1.625371e-4
GO:0051006 positive regulation of lipoprotein lipase activity 1.649275e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.701811e-4
GO:0031440 regulation of mRNA 3'-end processing 1.709394e-4
GO:0002467 germinal center formation 1.736565e-4
GO:0035249 synaptic transmission, glutamatergic 1.817160e-4
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.888739e-4
GO:0043303 mast cell degranulation 1.896015e-4
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1.966680e-4
GO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 2.027521e-4
GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification 2.027521e-4
GO:0043299 leukocyte degranulation 2.030664e-4
GO:0043243 positive regulation of protein complex disassembly 2.143121e-4
GO:0030259 lipid glycosylation 2.147174e-4
GO:0018230 peptidyl-L-cysteine S-palmitoylation 2.165472e-4
GO:0016068 type I hypersensitivity 2.165472e-4
GO:0006825 copper ion transport 2.384301e-4
GO:0009134 nucleoside diphosphate catabolic process 2.554521e-4
GO:0043691 reverse cholesterol transport 2.564675e-4
GO:0051956 negative regulation of amino acid transport 2.627990e-4
GO:0046889 positive regulation of lipid biosynthetic process 2.759340e-4
GO:0090281 negative regulation of calcium ion import 2.915169e-4
GO:0071584 negative regulation of zinc ion import 2.915169e-4
GO:0015788 UDP-N-acetylglucosamine transport 2.915169e-4
GO:0015790 UDP-xylose transport 2.915169e-4
GO:0070885 negative regulation of calcineurin-NFAT signaling pathway 2.915169e-4
GO:0045429 positive regulation of nitric oxide biosynthetic process 3.050194e-4
GO:0051583 dopamine uptake 3.053833e-4
GO:0001555 oocyte growth 3.127084e-4
GO:0008156 negative regulation of DNA replication 3.159644e-4
GO:0009181 purine ribonucleoside diphosphate catabolic process 3.308342e-4
GO:0070936 protein K48-linked ubiquitination 3.392809e-4
GO:0032513 negative regulation of protein phosphatase type 2B activity 3.493832e-4
GO:0016191 synaptic vesicle uncoating 3.493832e-4
GO:0046580 negative regulation of Ras protein signal transduction 3.559877e-4
GO:0060712 spongiotrophoblast layer development 3.722225e-4
GO:0034405 response to fluid shear stress 3.771167e-4
GO:0009185 ribonucleoside diphosphate metabolic process 3.903369e-4
GO:0023021 termination of signal transduction 4.214955e-4
GO:0045055 regulated secretory pathway 4.570300e-4
GO:0006878 cellular copper ion homeostasis 4.598615e-4
GO:0060896 neural plate pattern specification 4.811292e-4
GO:0070585 protein localization in mitochondrion 4.982397e-4
GO:0002155 regulation of thyroid hormone mediated signaling pathway 5.089570e-4
GO:0035094 response to nicotine 5.160412e-4
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 5.363048e-4
GO:0021997 neural plate axis specification 5.363048e-4
GO:0045428 regulation of nitric oxide biosynthetic process 5.510617e-4
GO:0000904 cell morphogenesis involved in differentiation 5.900050e-4
GO:0035404 histone-serine phosphorylation 6.026387e-4
GO:0021954 central nervous system neuron development 6.100002e-4
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 6.131895e-4
GO:0031929 TOR signaling cascade 6.150464e-4
GO:0045717 negative regulation of fatty acid biosynthetic process 6.155584e-4
GO:0006406 mRNA export from nucleus 6.180507e-4
GO:0051058 negative regulation of small GTPase mediated signal transduction 6.441842e-4
GO:2000143 negative regulation of transcription initiation, DNA-dependent 6.763572e-4
GO:0045085 negative regulation of interleukin-2 biosynthetic process 6.763572e-4
GO:0032728 positive regulation of interferon-beta production 7.026224e-4
GO:0060052 neurofilament cytoskeleton organization 7.179990e-4
GO:0009817 defense response to fungus, incompatible interaction 7.198267e-4
GO:0043623 cellular protein complex assembly 7.263804e-4
GO:0010970 microtubule-based transport 7.368943e-4
GO:0010936 negative regulation of macrophage cytokine production 7.415373e-4
GO:0072268 pattern specification involved in metanephros development 7.415373e-4
GO:0044243 multicellular organismal catabolic process 7.578406e-4
GO:0033700 phospholipid efflux 7.717587e-4
GO:0042994 cytoplasmic sequestering of transcription factor 7.816797e-4
GO:0046322 negative regulation of fatty acid oxidation 8.032311e-4
GO:0002385 mucosal immune response 8.079380e-4
GO:0045875 negative regulation of sister chromatid cohesion 8.300364e-4
GO:0045925 positive regulation of female receptivity 8.781164e-4
GO:0051481 reduction of cytosolic calcium ion concentration 8.888522e-4
GO:0006654 phosphatidic acid biosynthetic process 9.342717e-4
GO:0060997 dendritic spine morphogenesis 9.777377e-4
GO:0046890 regulation of lipid biosynthetic process 9.808836e-4
GO:0060711 labyrinthine layer development 1.018581e-3
GO:0071316 cellular response to nicotine 1.059657e-3
GO:2000273 positive regulation of receptor activity 1.083701e-3
GO:0019217 regulation of fatty acid metabolic process 1.084594e-3
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1.085870e-3
GO:0006098 pentose-phosphate shunt 1.119146e-3
GO:0030573 bile acid catabolic process 1.152254e-3
GO:0002125 maternal aggressive behavior 1.152254e-3
GO:0010845 positive regulation of reciprocal meiotic recombination 1.152254e-3
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.153998e-3
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 1.156595e-3
GO:0007630 jump response 1.156595e-3
GO:0001966 thigmotaxis 1.156595e-3
GO:0061005 cell differentiation involved in kidney development 1.188757e-3
GO:0021542 dentate gyrus development 1.193649e-3
GO:0043320 natural killer cell degranulation 1.197432e-3
GO:0045040 protein import into mitochondrial outer membrane 1.210582e-3
GO:0031442 positive regulation of mRNA 3'-end processing 1.235864e-3
GO:0042992 negative regulation of transcription factor import into nucleus 1.235946e-3
GO:0051299 centrosome separation 1.302128e-3
GO:0009191 ribonucleoside diphosphate catabolic process 1.302777e-3
GO:0009952 anterior/posterior pattern specification 1.346859e-3
GO:0045750 positive regulation of S phase of mitotic cell cycle 1.364895e-3
GO:0044091 membrane biogenesis 1.376409e-3
GO:0019367 fatty acid elongation, saturated fatty acid 1.376409e-3
GO:0045814 negative regulation of gene expression, epigenetic 1.413706e-3
GO:0071557 histone H3-K27 demethylation 1.442425e-3
GO:0035574 histone H4-K20 demethylation 1.442425e-3
GO:0033128 negative regulation of histone phosphorylation 1.442425e-3
GO:0031329 regulation of cellular catabolic process 1.442759e-3
GO:0071593 lymphocyte aggregation 1.443524e-3
GO:0060923 cardiac muscle cell fate commitment 1.457951e-3
GO:0006405 RNA export from nucleus 1.483223e-3
GO:0046885 regulation of hormone biosynthetic process 1.515320e-3
GO:0051897 positive regulation of protein kinase B signaling cascade 1.518996e-3
GO:0060125 negative regulation of growth hormone secretion 1.530043e-3
GO:0051463 negative regulation of cortisol secretion 1.530043e-3
GO:2000009 negative regulation of protein localization at cell surface 1.530043e-3
GO:0007057 spindle assembly involved in female meiosis I 1.530043e-3
GO:0021933 radial glia guided migration of cerebellar granule cell 1.530043e-3
GO:0021703 locus ceruleus development 1.530043e-3
GO:0090303 positive regulation of wound healing 1.555498e-3
GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning 1.555498e-3
GO:0003002 regionalization 1.573426e-3
GO:0006513 protein monoubiquitination 1.609551e-3
GO:0002062 chondrocyte differentiation 1.618619e-3
GO:0055070 copper ion homeostasis 1.620972e-3
GO:0002251 organ or tissue specific immune response 1.620972e-3
GO:0032479 regulation of type I interferon production 1.706188e-3
GO:0000422 mitochondrion degradation 1.744212e-3
GO:0042396 phosphagen biosynthetic process 1.744212e-3
GO:2000465 regulation of glycogen (starch) synthase activity 1.768593e-3
GO:0002719 negative regulation of cytokine production involved in immune response 1.811419e-3
GO:0045862 positive regulation of proteolysis 1.831574e-3
GO:0071585 detoxification of cadmium ion 1.834043e-3
GO:0044240 multicellular organismal lipid catabolic process 1.843074e-3
GO:0010984 regulation of lipoprotein particle clearance 1.868109e-3
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 1.873369e-3
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 1.873369e-3
GO:0030300 regulation of intestinal cholesterol absorption 1.896236e-3
GO:0032847 regulation of cellular pH reduction 1.901125e-3
GO:0010982 regulation of high-density lipoprotein particle clearance 1.909357e-3
GO:0090084 negative regulation of inclusion body assembly 1.935826e-3
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 1.936321e-3
GO:0051258 protein polymerization 1.999572e-3
GO:0006611 protein export from nucleus 2.008012e-3
GO:0050849 negative regulation of calcium-mediated signaling 2.118934e-3
GO:0051005 negative regulation of lipoprotein lipase activity 2.175840e-3
GO:0070169 positive regulation of biomineral tissue development 2.181974e-3
GO:0070831 basement membrane assembly 2.222748e-3
GO:0032203 telomere formation via telomerase 2.222748e-3
GO:0021547 midbrain-hindbrain boundary initiation 2.275142e-3
GO:0021501 prechordal plate formation 2.275142e-3
GO:0051017 actin filament bundle assembly 2.333057e-3
GO:0060266 negative regulation of respiratory burst involved in inflammatory response 2.375894e-3
GO:0061048 negative regulation of branching involved in lung morphogenesis 2.375894e-3
GO:0045994 positive regulation of translational initiation by iron 2.375894e-3
GO:0002037 negative regulation of L-glutamate transport 2.375894e-3
GO:0006540 glutamate decarboxylation to succinate 2.375894e-3
GO:0034116 positive regulation of heterotypic cell-cell adhesion 2.375894e-3
GO:0021539 subthalamus development 2.378503e-3
GO:0070076 histone lysine demethylation 2.400651e-3
GO:0001886 endothelial cell morphogenesis 2.412581e-3
GO:0055012 ventricular cardiac muscle cell differentiation 2.461492e-3
GO:0034619 cellular chaperone-mediated protein complex assembly 2.483025e-3
GO:0031536 positive regulation of exit from mitosis 2.604168e-3
GO:0019227 neuronal action potential propagation 2.642547e-3
GO:0035434 copper ion transmembrane transport 2.642547e-3
GO:0031103 axon regeneration 2.722824e-3
GO:0031102 neuron projection regeneration 2.802419e-3
GO:0035802 adrenal cortex formation 2.803097e-3
GO:0034259 negative regulation of Rho GTPase activity 2.886752e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 3.007853e-3
GO:0010985 negative regulation of lipoprotein particle clearance 3.071717e-3
GO:0007521 muscle cell fate determination 3.071717e-3
GO:0001963 synaptic transmission, dopaminergic 3.096478e-3
GO:0045176 apical protein localization 3.111379e-3
GO:0031331 positive regulation of cellular catabolic process 3.152905e-3
GO:0045103 intermediate filament-based process 3.317532e-3
GO:0046886 positive regulation of hormone biosynthetic process 3.337929e-3
GO:0030501 positive regulation of bone mineralization 3.345866e-3
GO:0007389 pattern specification process 3.387915e-3
GO:0042308 negative regulation of protein import into nucleus 3.406145e-3
GO:0046928 regulation of neurotransmitter secretion 3.412317e-3
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 3.455539e-3
GO:0015862 uridine transport 3.455539e-3
GO:0009296 flagellum assembly 3.465167e-3
GO:0051588 regulation of neurotransmitter transport 3.619554e-3
GO:0051298 centrosome duplication 3.631676e-3
GO:0010893 positive regulation of steroid biosynthetic process 3.650517e-3
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 3.650742e-3
GO:0070884 regulation of calcineurin-NFAT signaling pathway 3.650742e-3
GO:0022417 protein maturation by protein folding 3.650742e-3
GO:0015781 pyrimidine nucleotide-sugar transport 3.650742e-3
GO:0043153 entrainment of circadian clock by photoperiod 3.737510e-3
GO:0035583 negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta 3.737510e-3
GO:0072655 establishment of protein localization in mitochondrion 3.780770e-3
GO:0006198 cAMP catabolic process 3.781755e-3
GO:0014012 peripheral nervous system axon regeneration 3.889251e-3
GO:2000178 negative regulation of neural precursor cell proliferation 3.901452e-3
GO:0031508 centromeric heterochromatin formation 3.926969e-3
GO:0000189 MAPK import into nucleus 3.926969e-3
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration 3.926969e-3
GO:0010900 negative regulation of phosphatidylcholine catabolic process 3.939780e-3
GO:0045585 positive regulation of cytotoxic T cell differentiation 3.940372e-3
GO:0045110 intermediate filament bundle assembly 3.940372e-3
GO:0006699 bile acid biosynthetic process 3.959008e-3
GO:0003347 epicardial cell to mesenchymal cell transition 3.959008e-3
GO:0071803 positive regulation of podosome assembly 3.962744e-3
GO:0031584 activation of phospholipase D activity 3.962744e-3
GO:0006414 translational elongation 3.974837e-3
GO:0045579 positive regulation of B cell differentiation 4.020586e-3
GO:0061032 visceral serous pericardium development 4.231446e-3
GO:0006913 nucleocytoplasmic transport 4.251605e-3
GO:0034382 chylomicron remnant clearance 4.329090e-3
GO:0060996 dendritic spine development 4.329898e-3
GO:0060193 positive regulation of lipase activity 4.381111e-3
GO:0032383 regulation of intracellular cholesterol transport 4.437417e-3
GO:0001811 negative regulation of type I hypersensitivity 4.437417e-3
GO:0002638 negative regulation of immunoglobulin production 4.437417e-3
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 4.506964e-3
GO:0045401 positive regulation of interleukin-3 biosynthetic process 4.506964e-3
GO:0035850 epithelial cell differentiation involved in kidney development 4.542403e-3
GO:0030500 regulation of bone mineralization 4.643493e-3
GO:0070574 cadmium ion transmembrane transport 4.731391e-3
GO:0070301 cellular response to hydrogen peroxide 4.806165e-3
GO:0006184 GTP catabolic process 4.853012e-3
GO:0046784 intronless viral mRNA export from host nucleus 4.952720e-3
GO:0043467 regulation of generation of precursor metabolites and energy 4.960908e-3
GO:0060421 positive regulation of heart growth 4.982281e-3
GO:0050711 negative regulation of interleukin-1 secretion 4.982281e-3
GO:0035444 nickel ion transmembrane transport 5.078955e-3
GO:0007060 male meiosis chromosome segregation 5.078955e-3
GO:0001539 ciliary or flagellar motility 5.105247e-3
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 5.114221e-3
GO:0021871 forebrain regionalization 5.129964e-3
GO:0045723 positive regulation of fatty acid biosynthetic process 5.274369e-3
GO:2000195 negative regulation of female gonad development 5.423390e-3
GO:0090031 positive regulation of steroid hormone biosynthetic process 5.437216e-3
GO:0045576 mast cell activation 5.474013e-3
GO:0072284 metanephric S-shaped body morphogenesis 5.480687e-3
GO:0072278 metanephric comma-shaped body morphogenesis 5.480687e-3
GO:0010897 negative regulation of triglyceride catabolic process 5.480687e-3
GO:0010987 negative regulation of high-density lipoprotein particle clearance 5.480687e-3
GO:0042711 maternal behavior 5.540751e-3
GO:0034770 histone H4-K20 methylation 5.540751e-3
GO:0046128 purine ribonucleoside metabolic process 5.562862e-3
GO:0009648 photoperiodism 5.649164e-3
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 5.649164e-3
GO:0007095 mitotic cell cycle G2/M transition DNA damage checkpoint 5.996052e-3
GO:0043064 flagellum organization 6.024214e-3
GO:0070167 regulation of biomineral tissue development 6.130534e-3
GO:0000209 protein polyubiquitination 6.142318e-3
GO:0006626 protein targeting to mitochondrion 6.245132e-3
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 6.321885e-3
GO:0015864 pyrimidine nucleoside transport 6.321885e-3
GO:0045737 positive regulation of cyclin-dependent protein kinase activity 6.347381e-3
GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 6.439892e-3
GO:0071624 positive regulation of granulocyte chemotaxis 6.439892e-3
GO:0030150 protein import into mitochondrial matrix 6.439892e-3
GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 6.439892e-3
GO:0019290 siderophore biosynthetic process 6.439892e-3
GO:0002418 immune response to tumor cell 6.439892e-3
GO:0010157 response to chlorate 6.524074e-3
GO:0006931 substrate-dependent cell migration, cell attachment to substrate 6.524074e-3
GO:0042760 very long-chain fatty acid catabolic process 6.558976e-3
GO:0045175 basal protein localization 6.565645e-3
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 6.649942e-3
GO:0051169 nuclear transport 6.733311e-3
GO:0045940 positive regulation of steroid metabolic process 6.822706e-3
GO:0060191 regulation of lipase activity 6.929160e-3
GO:0006475 internal protein amino acid acetylation 6.933250e-3
GO:0090068 positive regulation of cell cycle process 6.967303e-3
GO:0007288 sperm axoneme assembly 7.005835e-3
GO:2000822 regulation of behavioral fear response 7.096020e-3
GO:0045116 protein neddylation 7.114923e-3
GO:0043457 regulation of cellular respiration 7.114923e-3
GO:0061181 regulation of chondrocyte development 7.249637e-3
GO:2000744 positive regulation of anterior head development 7.249637e-3
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 7.249637e-3
GO:0060028 convergent extension involved in axis elongation 7.249637e-3
GO:0019049 evasion of host defenses by virus 7.429167e-3
GO:0032713 negative regulation of interleukin-4 production 7.683158e-3
GO:0071279 cellular response to cobalt ion 7.736607e-3
GO:0070370 cellular heat acclimation 7.736607e-3
GO:0010637 negative regulation of mitochondrial fusion 7.736607e-3
GO:0043048 dolichyl monophosphate biosynthetic process 7.736607e-3
GO:0018960 4-nitrophenol metabolic process 7.736607e-3
GO:0060011 Sertoli cell proliferation 7.767609e-3
GO:0006102 isocitrate metabolic process 7.767609e-3
GO:0048050 post-embryonic eye morphogenesis 7.767609e-3
GO:0000902 cell morphogenesis 7.863556e-3
GO:0090231 regulation of spindle checkpoint 7.925888e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 7.942185e-3
GO:0060021 palate development 7.974485e-3
GO:0016079 synaptic vesicle exocytosis 7.999649e-3
GO:0032202 telomere assembly 8.244566e-3
GO:0006868 glutamine transport 8.251713e-3
GO:0034720 histone H3-K4 demethylation 8.388860e-3
GO:0007281 germ cell development 8.569011e-3
GO:0046006 regulation of activated T cell proliferation 8.630542e-3
GO:0002513 tolerance induction to self antigen 8.667745e-3
GO:0043461 proton-transporting ATP synthase complex assembly 8.667745e-3
GO:0002248 connective tissue replacement involved in inflammatory response wound healing 8.768947e-3
GO:0034616 response to laminar fluid shear stress 8.769595e-3
GO:0046058 cAMP metabolic process 8.918873e-3
GO:0072594 establishment of protein localization to organelle 8.976500e-3
GO:0032873 negative regulation of stress-activated MAPK cascade 9.134396e-3
GO:0072521 purine-containing compound metabolic process 9.156378e-3
GO:0051131 chaperone-mediated protein complex assembly 9.202727e-3
GO:0060555 induction of necroptosis by extracellular signals 9.202727e-3
GO:0060489 planar dichotomous subdivision of terminal units involved in lung branching morphogenesis 9.261646e-3
GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis 9.261646e-3
GO:0060490 lateral sprouting involved in lung morphogenesis 9.261646e-3
GO:0048105 establishment of body hair planar orientation 9.261646e-3
GO:0043697 cell dedifferentiation 9.261646e-3
GO:0046831 regulation of RNA export from nucleus 9.261646e-3
GO:0045104 intermediate filament cytoskeleton organization 9.283864e-3
GO:0034614 cellular response to reactive oxygen species 9.305940e-3
GO:0060259 regulation of feeding behavior 9.322498e-3
GO:0044058 regulation of digestive system process 9.406241e-3
GO:0033146 regulation of estrogen receptor signaling pathway 9.470498e-3
GO:0090030 regulation of steroid hormone biosynthetic process 9.572066e-3
GO:0006600 creatine metabolic process 9.639621e-3
GO:0071827 plasma lipoprotein particle organization 9.877510e-3
GO:0071711 basement membrane organization 9.879514e-3
GO:0000185 activation of MAPKKK activity 9.879514e-3
GO:0006436 tryptophanyl-tRNA aminoacylation 9.885630e-3
GO:0033211 adiponectin-mediated signaling pathway 9.899631e-3
GO:0035470 positive regulation of vascular wound healing 9.905454e-3
GO:0060821 inactivation of X chromosome by DNA methylation 9.905454e-3
GO:0045751 negative regulation of Toll signaling pathway 9.905454e-3
GO:0010616 negative regulation of cardiac muscle adaptation 9.905454e-3
GO:0019428 allantoin biosynthetic process 9.905454e-3
GO:0019858 cytosine metabolic process 9.905454e-3
GO:0018393 internal peptidyl-lysine acetylation 9.964335e-3
GO:0032446 protein modification by small protein conjugation 1.009113e-2
GO:0035562 negative regulation of chromatin binding 1.020903e-2
GO:0014053 negative regulation of gamma-aminobutyric acid secretion 1.020903e-2
GO:0033129 positive regulation of histone phosphorylation 1.020903e-2
GO:0015891 siderophore transport 1.020903e-2
GO:0034508 centromere complex assembly 1.043113e-2
GO:0006536 glutamate metabolic process 1.044364e-2
GO:0016567 protein ubiquitination 1.058471e-2
GO:0032352 positive regulation of hormone metabolic process 1.078892e-2
GO:0072015 glomerular visceral epithelial cell development 1.087050e-2
GO:0031394 positive regulation of prostaglandin biosynthetic process 1.090712e-2
GO:0032472 Golgi calcium ion transport 1.090854e-2
GO:0050760 negative regulation of thymidylate synthase biosynthetic process 1.090854e-2
GO:0042938 dipeptide transport 1.090854e-2
GO:0032468 Golgi calcium ion homeostasis 1.090854e-2
GO:0030026 cellular manganese ion homeostasis 1.090854e-2
GO:0009150 purine ribonucleotide metabolic process 1.098467e-2
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 1.102068e-2
GO:0002001 renin secretion into blood stream 1.102068e-2
GO:0032318 regulation of Ras GTPase activity 1.104628e-2
GO:0031507 heterochromatin formation 1.113042e-2
GO:0045948 positive regulation of translational initiation 1.121045e-2
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1.138936e-2
GO:0007044 cell-substrate junction assembly 1.144784e-2
GO:0038007 netrin-activated signaling pathway 1.163932e-2
GO:0060696 regulation of phospholipid catabolic process 1.163948e-2
GO:0051589 negative regulation of neurotransmitter transport 1.163948e-2
GO:0051973 positive regulation of telomerase activity 1.166530e-2
GO:0042891 antibiotic transport 1.166530e-2
GO:2000300 regulation of synaptic vesicle exocytosis 1.174623e-2
GO:2000194 regulation of female gonad development 1.174623e-2
GO:0034763 negative regulation of transmembrane transport 1.202213e-2
GO:0018394 peptidyl-lysine acetylation 1.209304e-2
GO:0031330 negative regulation of cellular catabolic process 1.211801e-2
GO:0006402 mRNA catabolic process 1.227899e-2
GO:0060122 inner ear receptor stereocilium organization 1.228602e-2
GO:0006415 translational termination 1.242100e-2
GO:0060591 chondroblast differentiation 1.242100e-2
GO:0000086 G2/M transition of mitotic cell cycle 1.253533e-2
GO:0000956 nuclear-transcribed mRNA catabolic process 1.279958e-2
GO:0010469 regulation of receptor activity 1.301372e-2
GO:0090208 positive regulation of triglyceride metabolic process 1.323501e-2
GO:0051532 regulation of NFAT protein import into nucleus 1.330182e-2
GO:0007099 centriole replication 1.335271e-2
GO:0031647 regulation of protein stability 1.339791e-2
GO:0051586 positive regulation of dopamine uptake 1.340475e-2
GO:0060032 notochord regression 1.340475e-2
GO:0048667 cell morphogenesis involved in neuron differentiation 1.342850e-2
GO:0030325 adrenal gland development 1.347173e-2
GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 1.364476e-2
GO:0060557 positive regulation of vitamin D biosynthetic process 1.368527e-2
GO:0044154 histone H3-K14 acetylation 1.368527e-2
GO:0072531 pyrimidine-containing compound transmembrane transport 1.384171e-2
GO:0031017 exocrine pancreas development 1.397832e-2
GO:0009954 proximal/distal pattern formation 1.438742e-2
GO:0032481 positive regulation of type I interferon production 1.444376e-2
GO:0045931 positive regulation of mitotic cell cycle 1.486105e-2
GO:0060119 inner ear receptor cell development 1.508144e-2
GO:0034377 plasma lipoprotein particle assembly 1.512848e-2
GO:0046039 GTP metabolic process 1.515385e-2
GO:0051382 kinetochore assembly 1.523467e-2
GO:0035520 monoubiquitinated protein deubiquitination 1.523467e-2
GO:0032980 keratinocyte activation 1.523467e-2
GO:0006195 purine nucleotide catabolic process 1.523552e-2
GO:0061013 regulation of mRNA catabolic process 1.527013e-2
GO:0090005 negative regulation of establishment of protein localization in plasma membrane 1.533451e-2
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1.533451e-2
GO:0048378 regulation of lateral mesodermal cell fate specification 1.533451e-2
GO:0000183 chromatin silencing at rDNA 1.537981e-2
GO:0048671 negative regulation of collateral sprouting 1.544657e-2
GO:0014002 astrocyte development 1.568579e-2
GO:0034369 plasma lipoprotein particle remodeling 1.589993e-2
GO:0031999 negative regulation of fatty acid beta-oxidation 1.605620e-2
GO:0002874 regulation of chronic inflammatory response to antigenic stimulus 1.605620e-2
GO:0008105 asymmetric protein localization 1.615237e-2
GO:0042136 neurotransmitter biosynthetic process 1.625911e-2
GO:0071352 cellular response to interleukin-2 1.628707e-2
GO:2000653 regulation of genetic imprinting 1.628707e-2
GO:0065002 intracellular protein transmembrane transport 1.628707e-2
GO:0046604 positive regulation of mitotic centrosome separation 1.628707e-2
GO:0002357 defense response to tumor cell 1.628707e-2
GO:0010891 negative regulation of sequestering of triglyceride 1.648403e-2
GO:0045924 regulation of female receptivity 1.662474e-2
GO:0009167 purine ribonucleoside monophosphate metabolic process 1.663668e-2
GO:0002541 activation of plasma proteins involved in acute inflammatory response 1.700569e-2
GO:0015804 neutral amino acid transport 1.737592e-2
GO:0019048 virus-host interaction 1.747676e-2
GO:0045806 negative regulation of endocytosis 1.762050e-2
GO:0031581 hemidesmosome assembly 1.779469e-2
GO:0048563 post-embryonic organ morphogenesis 1.779469e-2
GO:0046607 positive regulation of centrosome cycle 1.839063e-2