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Novel motif:41

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name:motif41_TSACAA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0050896 response to stimulus 4.375161e-73
GO:0042221 response to chemical stimulus 8.501461e-55
GO:0050789 regulation of biological process 7.856232e-50
GO:0023052 signaling 3.401041e-48
GO:0007165 signal transduction 4.042029e-48
GO:0065007 biological regulation 5.239501e-48
GO:0007154 cell communication 4.681751e-47
GO:0032501 multicellular organismal process 2.788571e-46
GO:0050794 regulation of cellular process 3.624950e-45
GO:0010038 response to metal ion 9.284913e-45
GO:0051716 cellular response to stimulus 3.391237e-44
GO:0051179 localization 3.416670e-42
GO:0006950 response to stress 1.810081e-40
GO:0009611 response to wounding 1.234640e-39
GO:0051234 establishment of localization 8.010189e-39
GO:0032502 developmental process 7.014543e-38
GO:0006810 transport 1.020016e-37
GO:0051592 response to calcium ion 3.731325e-36
GO:0042060 wound healing 4.169713e-36
GO:0010035 response to inorganic substance 6.616049e-36
GO:0002376 immune system process 9.617037e-36
GO:0001775 cell activation 1.464354e-33
GO:0007166 cell surface receptor linked signaling pathway 3.176843e-31
GO:0007275 multicellular organismal development 1.922725e-30
GO:0002684 positive regulation of immune system process 1.394239e-29
GO:0048856 anatomical structure development 4.194444e-29
GO:0002576 platelet degranulation 1.899332e-28
GO:0065008 regulation of biological quality 1.239461e-27
GO:0048769 sarcomerogenesis 6.434532e-27
GO:0030168 platelet activation 4.416387e-26
GO:0048583 regulation of response to stimulus 6.785394e-26
GO:0048513 organ development 1.529645e-25
GO:0009987 cellular process 2.853739e-25
GO:0007076 mitotic chromosome condensation 3.594566e-25
GO:0050790 regulation of catalytic activity 4.001802e-25
GO:0006928 cellular component movement 1.899269e-24
GO:0009888 tissue development 3.498757e-24
GO:0002682 regulation of immune system process 5.366854e-24
GO:0019220 regulation of phosphate metabolic process 9.807820e-24
GO:0007596 blood coagulation 2.811689e-23
GO:0055003 cardiac myofibril assembly 3.773613e-23
GO:0010033 response to organic substance 7.021146e-23
GO:0003008 system process 7.526906e-23
GO:0007599 hemostasis 8.243500e-23
GO:0002694 regulation of leukocyte activation 1.188423e-22
GO:0016192 vesicle-mediated transport 1.917627e-22
GO:0032879 regulation of localization 2.158866e-22
GO:0051338 regulation of transferase activity 2.776788e-22
GO:0042325 regulation of phosphorylation 3.064471e-22
GO:0050878 regulation of body fluid levels 1.758829e-21
GO:0030240 skeletal muscle thin filament assembly 2.822342e-21
GO:0000070 mitotic sister chromatid segregation 3.524259e-21
GO:0000819 sister chromatid segregation 5.451836e-21
GO:0048731 system development 5.805450e-21
GO:0050865 regulation of cell activation 6.062225e-21
GO:0046903 secretion 8.188092e-21
GO:0006911 phagocytosis, engulfment 9.797741e-21
GO:0044238 primary metabolic process 1.051592e-20
GO:0030261 chromosome condensation 1.741004e-20
GO:0019222 regulation of metabolic process 1.803880e-20
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 2.409181e-20
GO:0030241 skeletal muscle myosin thick filament assembly 4.257041e-20
GO:0001932 regulation of protein phosphorylation 5.500969e-20
GO:0043549 regulation of kinase activity 5.895156e-20
GO:0008152 metabolic process 6.664054e-20
GO:0006955 immune response 1.228741e-19
GO:0006952 defense response 1.306212e-19
GO:0032026 response to magnesium ion 1.993994e-19
GO:0031399 regulation of protein modification process 2.716983e-19
GO:0048519 negative regulation of biological process 7.253311e-19
GO:0048518 positive regulation of biological process 7.899567e-19
GO:0055013 cardiac muscle cell development 8.146591e-19
GO:0007517 muscle organ development 8.409068e-19
GO:0048644 muscle organ morphogenesis 1.435497e-18
GO:0031323 regulation of cellular metabolic process 1.768407e-18
GO:0043032 positive regulation of macrophage activation 2.919863e-18
GO:0051049 regulation of transport 4.563873e-18
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 5.804056e-18
GO:0006629 lipid metabolic process 1.079910e-17
GO:0048522 positive regulation of cellular process 1.527660e-17
GO:0018149 peptide cross-linking 1.648339e-17
GO:0071840 cellular component organization or biogenesis 1.730134e-17
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 2.243411e-17
GO:0048584 positive regulation of response to stimulus 3.188290e-17
GO:0065009 regulation of molecular function 3.235052e-17
GO:0002690 positive regulation of leukocyte chemotaxis 3.477022e-17
GO:0002696 positive regulation of leukocyte activation 4.261663e-17
GO:0048869 cellular developmental process 5.968783e-17
GO:0050867 positive regulation of cell activation 8.969089e-17
GO:2000191 regulation of fatty acid transport 9.487011e-17
GO:0080090 regulation of primary metabolic process 9.512273e-17
GO:0060415 muscle tissue morphogenesis 1.056045e-16
GO:0002687 positive regulation of leukocyte migration 1.205039e-16
GO:0014706 striated muscle tissue development 1.235143e-16
GO:0019538 protein metabolic process 1.286070e-16
GO:0010466 negative regulation of peptidase activity 1.310711e-16
GO:0016043 cellular component organization 1.435745e-16
GO:0032101 regulation of response to external stimulus 1.736797e-16
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 1.740246e-16
GO:0045859 regulation of protein kinase activity 1.847283e-16
GO:0032940 secretion by cell 1.878544e-16
GO:0048468 cell development 1.981435e-16
GO:0043652 engulfment of apoptotic cell 2.266778e-16
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.266778e-16
GO:0010754 negative regulation of cGMP-mediated signaling 2.266778e-16
GO:0010751 negative regulation of nitric oxide mediated signal transduction 2.266778e-16
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 2.266778e-16
GO:0045765 regulation of angiogenesis 2.506433e-16
GO:0050795 regulation of behavior 3.500897e-16
GO:0002688 regulation of leukocyte chemotaxis 3.585529e-16
GO:0051893 regulation of focal adhesion assembly 3.983832e-16
GO:0055008 cardiac muscle tissue morphogenesis 4.030139e-16
GO:0009607 response to biotic stimulus 4.489532e-16
GO:0006897 endocytosis 6.388997e-16
GO:0002683 negative regulation of immune system process 7.174098e-16
GO:0045214 sarcomere organization 7.195035e-16
GO:0006954 inflammatory response 8.168545e-16
GO:0050776 regulation of immune response 9.803888e-16
GO:0032268 regulation of cellular protein metabolic process 1.048267e-15
GO:0071634 regulation of transforming growth factor beta production 1.129243e-15
GO:0009617 response to bacterium 1.205882e-15
GO:0050920 regulation of chemotaxis 1.238677e-15
GO:0072358 cardiovascular system development 1.496350e-15
GO:0009893 positive regulation of metabolic process 1.670971e-15
GO:0060537 muscle tissue development 1.677103e-15
GO:0048739 cardiac muscle fiber development 1.743297e-15
GO:0055007 cardiac muscle cell differentiation 1.806448e-15
GO:0048585 negative regulation of response to stimulus 1.992051e-15
GO:0014866 skeletal myofibril assembly 2.127193e-15
GO:0023051 regulation of signaling 2.298140e-15
GO:0030154 cell differentiation 2.419512e-15
GO:0051249 regulation of lymphocyte activation 2.823043e-15
GO:0060255 regulation of macromolecule metabolic process 3.485607e-15
GO:0050793 regulation of developmental process 3.573271e-15
GO:0009966 regulation of signal transduction 3.970690e-15
GO:0051707 response to other organism 4.326682e-15
GO:0009628 response to abiotic stimulus 5.340815e-15
GO:0009653 anatomical structure morphogenesis 6.278657e-15
GO:0051336 regulation of hydrolase activity 6.690386e-15
GO:0008202 steroid metabolic process 6.816577e-15
GO:0002685 regulation of leukocyte migration 1.020737e-14
GO:0046459 short-chain fatty acid metabolic process 1.036062e-14
GO:0006869 lipid transport 1.326080e-14
GO:0043086 negative regulation of catalytic activity 1.425789e-14
GO:0006887 exocytosis 1.718131e-14
GO:0002237 response to molecule of bacterial origin 2.167409e-14
GO:0010876 lipid localization 2.304984e-14
GO:0043030 regulation of macrophage activation 2.536931e-14
GO:0044237 cellular metabolic process 2.660420e-14
GO:0048523 negative regulation of cellular process 2.738192e-14
GO:0070887 cellular response to chemical stimulus 3.316145e-14
GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 3.582155e-14
GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 3.582155e-14
GO:0051895 negative regulation of focal adhesion assembly 3.708599e-14
GO:0015722 canalicular bile acid transport 3.765665e-14
GO:0006909 phagocytosis 3.793864e-14
GO:0006811 ion transport 4.039130e-14
GO:0016477 cell migration 4.105971e-14
GO:0042180 cellular ketone metabolic process 4.257613e-14
GO:0019752 carboxylic acid metabolic process 4.314203e-14
GO:0048520 positive regulation of behavior 4.385783e-14
GO:0040011 locomotion 4.560805e-14
GO:0048870 cell motility 4.924016e-14
GO:0052547 regulation of peptidase activity 5.390325e-14
GO:0046638 positive regulation of alpha-beta T cell differentiation 5.800241e-14
GO:0002253 activation of immune response 6.988120e-14
GO:0051704 multi-organism process 7.158656e-14
GO:0032496 response to lipopolysaccharide 8.409644e-14
GO:0048747 muscle fiber development 9.073123e-14
GO:0043170 macromolecule metabolic process 9.371536e-14
GO:0032914 positive regulation of transforming growth factor beta1 production 9.938663e-14
GO:0006464 protein modification process 1.056209e-13
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 1.290010e-13
GO:0032908 regulation of transforming growth factor beta1 production 1.381811e-13
GO:2000026 regulation of multicellular organismal development 1.473795e-13
GO:0050864 regulation of B cell activation 1.534644e-13
GO:0009968 negative regulation of signal transduction 1.575293e-13
GO:0050869 negative regulation of B cell activation 1.808722e-13
GO:0050778 positive regulation of immune response 1.850475e-13
GO:0050877 neurological system process 1.899456e-13
GO:0051641 cellular localization 2.101751e-13
GO:0022402 cell cycle process 2.134748e-13
GO:0023057 negative regulation of signaling 2.398865e-13
GO:0015718 monocarboxylic acid transport 2.759851e-13
GO:0055002 striated muscle cell development 2.923055e-13
GO:0010648 negative regulation of cell communication 3.448763e-13
GO:0006082 organic acid metabolic process 3.633846e-13
GO:0051246 regulation of protein metabolic process 3.648610e-13
GO:0052548 regulation of endopeptidase activity 5.260532e-13
GO:0003006 developmental process involved in reproduction 5.627618e-13
GO:0046635 positive regulation of alpha-beta T cell activation 7.638672e-13
GO:0061041 regulation of wound healing 7.693139e-13
GO:0035051 cardiac cell differentiation 8.853686e-13
GO:0000188 inactivation of MAPK activity 9.597723e-13
GO:0032695 negative regulation of interleukin-12 production 1.324179e-12
GO:0050921 positive regulation of chemotaxis 1.470346e-12
GO:0002544 chronic inflammatory response 1.547071e-12
GO:0003007 heart morphogenesis 1.639094e-12
GO:0043438 acetoacetic acid metabolic process 1.852888e-12
GO:0032989 cellular component morphogenesis 1.896955e-12
GO:0007049 cell cycle 2.107377e-12
GO:0010759 positive regulation of macrophage chemotaxis 2.198805e-12
GO:0050678 regulation of epithelial cell proliferation 2.286227e-12
GO:0032787 monocarboxylic acid metabolic process 2.395041e-12
GO:0015721 bile acid and bile salt transport 2.501867e-12
GO:0007507 heart development 2.683572e-12
GO:0055001 muscle cell development 3.024598e-12
GO:0061061 muscle structure development 3.162899e-12
GO:0034638 phosphatidylcholine catabolic process 3.468948e-12
GO:0002520 immune system development 3.611648e-12
GO:0048660 regulation of smooth muscle cell proliferation 3.636713e-12
GO:0043409 negative regulation of MAPKKK cascade 4.268588e-12
GO:0010604 positive regulation of macromolecule metabolic process 4.309994e-12
GO:0070536 protein K63-linked deubiquitination 5.927683e-12
GO:0042493 response to drug 5.971613e-12
GO:0034139 regulation of toll-like receptor 3 signaling pathway 6.280412e-12
GO:0048738 cardiac muscle tissue development 7.224404e-12
GO:0071622 regulation of granulocyte chemotaxis 7.262495e-12
GO:0045321 leukocyte activation 7.546838e-12
GO:0006796 phosphate-containing compound metabolic process 8.005952e-12
GO:0010758 regulation of macrophage chemotaxis 8.240226e-12
GO:2000345 regulation of hepatocyte proliferation 8.405409e-12
GO:0006941 striated muscle contraction 8.700172e-12
GO:0006323 DNA packaging 8.932864e-12
GO:0046634 regulation of alpha-beta T cell activation 9.408917e-12
GO:0002764 immune response-regulating signaling pathway 1.028680e-11
GO:0090291 negative regulation of osteoclast proliferation 1.235827e-11
GO:2000349 negative regulation of CD40 signaling pathway 1.235827e-11
GO:2000347 positive regulation of hepatocyte proliferation 1.235827e-11
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.235827e-11
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 1.235827e-11
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.235827e-11
GO:0072573 tolerance induction to lipopolysaccharide 1.235827e-11
GO:0051649 establishment of localization in cell 1.242572e-11
GO:0010757 negative regulation of plasminogen activation 1.299605e-11
GO:0043412 macromolecule modification 1.354623e-11
GO:0009894 regulation of catabolic process 1.603204e-11
GO:0045621 positive regulation of lymphocyte differentiation 1.623401e-11
GO:0002757 immune response-activating signal transduction 1.625344e-11
GO:0045740 positive regulation of DNA replication 1.676491e-11
GO:0048608 reproductive structure development 1.857433e-11
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway 1.875934e-11
GO:0044092 negative regulation of molecular function 1.983499e-11
GO:0030335 positive regulation of cell migration 2.183393e-11
GO:0010646 regulation of cell communication 2.336689e-11
GO:0040007 growth 2.575118e-11
GO:0051346 negative regulation of hydrolase activity 2.601848e-11
GO:0034135 regulation of toll-like receptor 2 signaling pathway 2.691573e-11
GO:0048646 anatomical structure formation involved in morphogenesis 2.877516e-11
GO:0044267 cellular protein metabolic process 2.903490e-11
GO:0007059 chromosome segregation 3.061943e-11
GO:0080134 regulation of response to stress 3.066020e-11
GO:0032890 regulation of organic acid transport 4.362099e-11
GO:0032103 positive regulation of response to external stimulus 4.973172e-11
GO:0046637 regulation of alpha-beta T cell differentiation 5.274549e-11
GO:0031325 positive regulation of cellular metabolic process 6.002851e-11
GO:0071675 regulation of mononuclear cell migration 6.068091e-11
GO:0044255 cellular lipid metabolic process 6.541367e-11
GO:0048729 tissue morphogenesis 6.560787e-11
GO:0043154 negative regulation of caspase activity 6.729439e-11
GO:0072507 divalent inorganic cation homeostasis 6.769615e-11
GO:0030239 myofibril assembly 6.799716e-11
GO:0010763 positive regulation of fibroblast migration 6.968623e-11
GO:0030595 leukocyte chemotaxis 7.120050e-11
GO:0010595 positive regulation of endothelial cell migration 7.431510e-11
GO:0051348 negative regulation of transferase activity 7.830585e-11
GO:2000147 positive regulation of cell motility 8.999778e-11
GO:0019605 butyrate metabolic process 1.010531e-10
GO:0010755 regulation of plasminogen activation 1.094462e-10
GO:0010955 negative regulation of protein processing 1.131271e-10
GO:0045088 regulation of innate immune response 1.162209e-10
GO:0031032 actomyosin structure organization 1.393831e-10
GO:0046689 response to mercury ion 1.522392e-10
GO:0001936 regulation of endothelial cell proliferation 1.585794e-10
GO:0007186 G-protein coupled receptor protein signaling pathway 1.614055e-10
GO:0045766 positive regulation of angiogenesis 1.707863e-10
GO:0009056 catabolic process 1.732855e-10
GO:0043085 positive regulation of catalytic activity 1.909601e-10
GO:0071103 DNA conformation change 2.002068e-10
GO:0045137 development of primary sexual characteristics 2.033416e-10
GO:0031349 positive regulation of defense response 2.042505e-10
GO:0007040 lysosome organization 2.319443e-10
GO:0032891 negative regulation of organic acid transport 2.523854e-10
GO:0042692 muscle cell differentiation 2.635463e-10
GO:0060068 vagina development 2.709311e-10
GO:0051251 positive regulation of lymphocyte activation 2.885149e-10
GO:0051146 striated muscle cell differentiation 2.997440e-10
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 2.999362e-10
GO:0044281 small molecule metabolic process 3.162105e-10
GO:0071636 positive regulation of transforming growth factor beta production 3.270362e-10
GO:0048511 rhythmic process 4.031848e-10
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 4.417133e-10
GO:0001525 angiogenesis 4.519448e-10
GO:0046851 negative regulation of bone remodeling 4.652763e-10
GO:0043623 cellular protein complex assembly 4.762055e-10
GO:0030334 regulation of cell migration 4.835577e-10
GO:0043067 regulation of programmed cell death 5.159559e-10
GO:0000085 G2 phase of mitotic cell cycle 5.168437e-10
GO:0009605 response to external stimulus 5.170015e-10
GO:0055074 calcium ion homeostasis 6.027683e-10
GO:0009725 response to hormone stimulus 6.264947e-10
GO:0045779 negative regulation of bone resorption 6.306308e-10
GO:0048853 forebrain morphogenesis 7.073838e-10
GO:0006875 cellular metal ion homeostasis 7.167678e-10
GO:0035335 peptidyl-tyrosine dephosphorylation 7.420211e-10
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 7.556698e-10
GO:0010941 regulation of cell death 7.713259e-10
GO:0051094 positive regulation of developmental process 8.051089e-10
GO:0034373 intermediate-density lipoprotein particle remodeling 8.108580e-10
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 8.301206e-10
GO:0010741 negative regulation of intracellular protein kinase cascade 8.342137e-10
GO:0006874 cellular calcium ion homeostasis 9.202544e-10
GO:0050679 positive regulation of epithelial cell proliferation 9.423696e-10
GO:0040017 positive regulation of locomotion 1.124937e-9
GO:0048534 hemopoietic or lymphoid organ development 1.128904e-9
GO:0072503 cellular divalent inorganic cation homeostasis 1.170940e-9
GO:0044260 cellular macromolecule metabolic process 1.206324e-9
GO:0045582 positive regulation of T cell differentiation 1.257627e-9
GO:0050701 interleukin-1 secretion 1.289540e-9
GO:0007155 cell adhesion 1.412952e-9
GO:0032494 response to peptidoglycan 1.539119e-9
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 1.568251e-9
GO:0007548 sex differentiation 1.676888e-9
GO:0051171 regulation of nitrogen compound metabolic process 1.706285e-9
GO:0046660 female sex differentiation 1.727345e-9
GO:0048732 gland development 1.770978e-9
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 2.177956e-9
GO:0055065 metal ion homeostasis 2.326626e-9
GO:0042592 homeostatic process 2.416573e-9
GO:0048609 multicellular organismal reproductive process 2.452066e-9
GO:0033673 negative regulation of kinase activity 2.456446e-9
GO:0034762 regulation of transmembrane transport 2.512284e-9
GO:0045428 regulation of nitric oxide biosynthetic process 2.513924e-9
GO:2000116 regulation of cysteine-type endopeptidase activity 2.545924e-9
GO:0042981 regulation of apoptosis 2.577578e-9
GO:0042327 positive regulation of phosphorylation 2.619581e-9
GO:0035556 intracellular signal transduction 2.699668e-9
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 2.867892e-9
GO:2000352 negative regulation of endothelial cell apoptosis 3.070683e-9
GO:0030097 hemopoiesis 3.293655e-9
GO:0045089 positive regulation of innate immune response 3.311744e-9
GO:0042632 cholesterol homeostasis 3.559669e-9
GO:0019433 triglyceride catabolic process 3.859312e-9
GO:0007267 cell-cell signaling 3.981097e-9
GO:0033036 macromolecule localization 3.983233e-9
GO:0006275 regulation of DNA replication 4.123413e-9
GO:0048566 embryonic digestive tract development 4.155811e-9
GO:0002053 positive regulation of mesenchymal cell proliferation 4.261485e-9
GO:0045937 positive regulation of phosphate metabolic process 4.339127e-9
GO:0022602 ovulation cycle process 4.373596e-9
GO:0019219 regulation of nucleobase-containing compound metabolic process 4.381645e-9
GO:0051050 positive regulation of transport 4.449178e-9
GO:0009891 positive regulation of biosynthetic process 4.466737e-9
GO:0001922 B-1 B cell homeostasis 4.485975e-9
GO:0042698 ovulation cycle 4.569126e-9
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 4.638755e-9
GO:0060429 epithelium development 4.690250e-9
GO:0045627 positive regulation of T-helper 1 cell differentiation 4.716196e-9
GO:0007204 elevation of cytosolic calcium ion concentration 4.805170e-9
GO:0019725 cellular homeostasis 4.812115e-9
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 5.000240e-9
GO:0030155 regulation of cell adhesion 5.150321e-9
GO:0006468 protein phosphorylation 5.196465e-9
GO:0051272 positive regulation of cellular component movement 5.367255e-9
GO:0055088 lipid homeostasis 5.369936e-9
GO:0060548 negative regulation of cell death 6.085859e-9
GO:0032612 interleukin-1 production 6.107437e-9
GO:0043536 positive regulation of blood vessel endothelial cell migration 6.245204e-9
GO:0045429 positive regulation of nitric oxide biosynthetic process 6.649602e-9
GO:0034605 cellular response to heat 6.683306e-9
GO:0045624 positive regulation of T-helper cell differentiation 6.876268e-9
GO:0001816 cytokine production 7.036331e-9
GO:2000348 regulation of CD40 signaling pathway 7.214553e-9
GO:0016044 cellular membrane organization 7.993913e-9
GO:0040012 regulation of locomotion 8.025499e-9
GO:0048661 positive regulation of smooth muscle cell proliferation 8.123463e-9
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation 8.911765e-9
GO:0051345 positive regulation of hydrolase activity 9.331560e-9
GO:2000351 regulation of endothelial cell apoptosis 9.365772e-9
GO:0045087 innate immune response 9.798215e-9
GO:0070301 cellular response to hydrogen peroxide 1.004158e-8
GO:0046649 lymphocyte activation 1.009297e-8
GO:0032663 regulation of interleukin-2 production 1.034405e-8
GO:0044248 cellular catabolic process 1.044214e-8
GO:0010557 positive regulation of macromolecule biosynthetic process 1.092815e-8
GO:0034143 regulation of toll-like receptor 4 signaling pathway 1.113774e-8
GO:0007276 gamete generation 1.191857e-8
GO:0061024 membrane organization 1.212035e-8
GO:0051917 regulation of fibrinolysis 1.235854e-8
GO:2000145 regulation of cell motility 1.375752e-8
GO:0006812 cation transport 1.405142e-8
GO:0070663 regulation of leukocyte proliferation 1.529464e-8
GO:0050870 positive regulation of T cell activation 1.546523e-8
GO:0055114 oxidation-reduction process 1.618958e-8
GO:0002604 regulation of dendritic cell antigen processing and presentation 1.790349e-8
GO:0030193 regulation of blood coagulation 1.810612e-8
GO:0006109 regulation of carbohydrate metabolic process 1.819961e-8
GO:0055080 cation homeostasis 1.891409e-8
GO:0046475 glycerophospholipid catabolic process 1.912818e-8
GO:0032317 regulation of Rap GTPase activity 1.928372e-8
GO:0002218 activation of innate immune response 1.942170e-8
GO:0051250 negative regulation of lymphocyte activation 1.997563e-8
GO:0043069 negative regulation of programmed cell death 2.036195e-8
GO:0043537 negative regulation of blood vessel endothelial cell migration 2.117801e-8
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 2.167907e-8
GO:0010464 regulation of mesenchymal cell proliferation 2.204340e-8
GO:0006916 anti-apoptosis 2.474203e-8
GO:0060749 mammary gland alveolus development 2.547026e-8
GO:0007417 central nervous system development 2.646400e-8
GO:0006470 protein dephosphorylation 2.723590e-8
GO:0001952 regulation of cell-matrix adhesion 2.726991e-8
GO:0051054 positive regulation of DNA metabolic process 2.762238e-8
GO:0050900 leukocyte migration 2.826098e-8
GO:0050931 pigment cell differentiation 2.855728e-8
GO:0043405 regulation of MAP kinase activity 3.281264e-8
GO:0009719 response to endogenous stimulus 3.342030e-8
GO:0008406 gonad development 3.395087e-8
GO:0032844 regulation of homeostatic process 3.515895e-8
GO:0007033 vacuole organization 3.557311e-8
GO:0016125 sterol metabolic process 3.575915e-8
GO:0022612 gland morphogenesis 3.831801e-8
GO:0060538 skeletal muscle organ development 3.895303e-8
GO:0019226 transmission of nerve impulse 3.986939e-8
GO:0050818 regulation of coagulation 4.118534e-8
GO:0008219 cell death 4.241916e-8
GO:0051248 negative regulation of protein metabolic process 4.339298e-8
GO:0007519 skeletal muscle tissue development 4.359334e-8
GO:0010675 regulation of cellular carbohydrate metabolic process 4.377102e-8
GO:0002832 negative regulation of response to biotic stimulus 4.666113e-8
GO:0022603 regulation of anatomical structure morphogenesis 4.892524e-8
GO:0030850 prostate gland development 5.061678e-8
GO:0046716 muscle cell homeostasis 5.189938e-8
GO:0071842 cellular component organization at cellular level 5.199635e-8
GO:0001655 urogenital system development 5.250602e-8
GO:0030049 muscle filament sliding 5.330058e-8
GO:0032652 regulation of interleukin-1 production 5.500681e-8
GO:0016311 dephosphorylation 5.786422e-8
GO:0010269 response to selenium ion 6.407772e-8
GO:0050663 cytokine secretion 6.446220e-8
GO:0002577 regulation of antigen processing and presentation 6.643942e-8
GO:0070252 actin-mediated cell contraction 6.682728e-8
GO:0042953 lipoprotein transport 6.718793e-8
GO:0051918 negative regulation of fibrinolysis 6.758639e-8
GO:0034104 negative regulation of tissue remodeling 6.810226e-8
GO:0051570 regulation of histone H3-K9 methylation 6.818045e-8
GO:0030888 regulation of B cell proliferation 6.895377e-8
GO:0006816 calcium ion transport 7.082557e-8
GO:2000379 positive regulation of reactive oxygen species metabolic process 7.094874e-8
GO:0050702 interleukin-1 beta secretion 7.279235e-8
GO:0035162 embryonic hemopoiesis 7.509229e-8
GO:0007229 integrin-mediated signaling pathway 7.860473e-8
GO:0008037 cell recognition 7.905685e-8
GO:0006807 nitrogen compound metabolic process 8.002420e-8
GO:0003012 muscle system process 8.038373e-8
GO:0032854 positive regulation of Rap GTPase activity 8.259803e-8
GO:0016265 death 8.426809e-8
GO:0006935 chemotaxis 8.443116e-8
GO:0010828 positive regulation of glucose transport 8.468164e-8
GO:0031329 regulation of cellular catabolic process 8.622492e-8
GO:0034763 negative regulation of transmembrane transport 8.661948e-8
GO:0001780 neutrophil homeostasis 8.663629e-8
GO:0051574 positive regulation of histone H3-K9 methylation 9.233926e-8
GO:0031328 positive regulation of cellular biosynthetic process 9.782339e-8
GO:0043066 negative regulation of apoptosis 9.946074e-8
GO:0007268 synaptic transmission 1.093022e-7
GO:0032703 negative regulation of interleukin-2 production 1.105915e-7
GO:0071841 cellular component organization or biogenesis at cellular level 1.111586e-7
GO:0046503 glycerolipid catabolic process 1.135488e-7
GO:0002695 negative regulation of leukocyte activation 1.152097e-7
GO:0032495 response to muramyl dipeptide 1.161595e-7
GO:0070101 positive regulation of chemokine-mediated signaling pathway 1.182237e-7
GO:0014048 regulation of glutamate secretion 1.189538e-7
GO:0051480 cytosolic calcium ion homeostasis 1.267094e-7
GO:0007528 neuromuscular junction development 1.271312e-7
GO:0046545 development of primary female sexual characteristics 1.326000e-7
GO:0001667 ameboidal cell migration 1.347343e-7
GO:0071901 negative regulation of protein serine/threonine kinase activity 1.378587e-7
GO:0006469 negative regulation of protein kinase activity 1.400055e-7
GO:0030003 cellular cation homeostasis 1.557592e-7
GO:0032651 regulation of interleukin-1 beta production 1.648096e-7
GO:0030522 intracellular receptor mediated signaling pathway 1.657266e-7
GO:0008585 female gonad development 1.662564e-7
GO:0021509 roof plate formation 1.774888e-7
GO:0070613 regulation of protein processing 1.782934e-7
GO:0010885 regulation of cholesterol storage 1.818780e-7
GO:0046464 acylglycerol catabolic process 1.831221e-7
GO:0012501 programmed cell death 1.846784e-7
GO:0071900 regulation of protein serine/threonine kinase activity 1.930695e-7
GO:0030318 melanocyte differentiation 1.993725e-7
GO:0043535 regulation of blood vessel endothelial cell migration 2.033660e-7
GO:0001961 positive regulation of cytokine-mediated signaling pathway 2.111750e-7
GO:0050708 regulation of protein secretion 2.120285e-7
GO:0044036 cell wall macromolecule metabolic process 2.137779e-7
GO:0010927 cellular component assembly involved in morphogenesis 2.167197e-7
GO:0006508 proteolysis 2.198393e-7
GO:0051052 regulation of DNA metabolic process 2.246991e-7
GO:0042127 regulation of cell proliferation 2.249860e-7
GO:0051128 regulation of cellular component organization 2.285544e-7
GO:0006083 acetate metabolic process 2.296568e-7
GO:0071827 plasma lipoprotein particle organization 2.407694e-7


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0050896 response to stimulus 2.300564e-17
GO:0009605 response to external stimulus 1.953597e-16
GO:0006581 acetylcholine catabolic process 2.245051e-15
GO:0030488 tRNA methylation 4.597108e-13
GO:0051716 cellular response to stimulus 7.434029e-13
GO:0008291 acetylcholine metabolic process 1.920591e-12
GO:0031667 response to nutrient levels 4.940935e-12
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 1.155163e-11
GO:0007584 response to nutrient 2.209935e-11
GO:0023052 signaling 3.750566e-10
GO:0007154 cell communication 3.985226e-10
GO:0007165 signal transduction 4.856079e-10
GO:0009991 response to extracellular stimulus 5.602595e-10
GO:0006952 defense response 9.998274e-10
GO:0051704 multi-organism process 1.089912e-9
GO:0019695 choline metabolic process 1.126289e-9
GO:0002455 humoral immune response mediated by circulating immunoglobulin 1.238113e-9
GO:0045213 neurotransmitter receptor metabolic process 1.378120e-9
GO:0002076 osteoblast development 1.651510e-9
GO:0035588 G-protein coupled purinergic receptor signaling pathway 2.016629e-9
GO:0019730 antimicrobial humoral response 2.408791e-9
GO:0065008 regulation of biological quality 3.021411e-9
GO:0006950 response to stress 4.266422e-9
GO:0007033 vacuole organization 7.129979e-9
GO:0035590 purinergic nucleotide receptor signaling pathway 7.189507e-9
GO:0009310 amine catabolic process 1.046271e-8
GO:0042221 response to chemical stimulus 1.053127e-8
GO:0030183 B cell differentiation 1.688288e-8
GO:0045212 neurotransmitter receptor biosynthetic process 1.831897e-8
GO:0007600 sensory perception 1.840018e-8
GO:0007166 cell surface receptor linked signaling pathway 1.892855e-8
GO:0045187 regulation of circadian sleep/wake cycle, sleep 2.358598e-8
GO:0051707 response to other organism 2.410042e-8
GO:0009628 response to abiotic stimulus 2.598750e-8
GO:0007040 lysosome organization 2.921560e-8
GO:0009617 response to bacterium 3.316325e-8
GO:0002684 positive regulation of immune system process 3.637777e-8
GO:0019731 antibacterial humoral response 4.900982e-8
GO:0009607 response to biotic stimulus 5.272429e-8
GO:0042832 defense response to protozoan 5.585404e-8
GO:0050865 regulation of cell activation 7.310773e-8
GO:0019836 hemolysis by symbiont of host erythrocytes 7.893686e-8
GO:0032501 multicellular organismal process 8.119562e-8
GO:0002313 mature B cell differentiation involved in immune response 8.682195e-8
GO:0002252 immune effector process 9.397855e-8
GO:0001562 response to protozoan 9.579793e-8
GO:0002694 regulation of leukocyte activation 1.025342e-7
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 1.225922e-7
GO:0042438 melanin biosynthetic process 1.349916e-7
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 1.388349e-7
GO:0007156 homophilic cell adhesion 1.790317e-7
GO:0035587 purinergic receptor signaling pathway 1.880392e-7
GO:0007286 spermatid development 2.026701e-7
GO:0045621 positive regulation of lymphocyte differentiation 2.057242e-7
GO:0007599 hemostasis 2.345216e-7
GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 2.987105e-7
GO:0022410 circadian sleep/wake cycle process 2.997961e-7
GO:0002682 regulation of immune system process 3.180165e-7
GO:0002521 leukocyte differentiation 3.321611e-7
GO:0042745 circadian sleep/wake cycle 3.402168e-7
GO:0007596 blood coagulation 3.507708e-7
GO:0048513 organ development 3.602616e-7
GO:0070541 response to platinum ion 4.144269e-7
GO:0002696 positive regulation of leukocyte activation 4.530376e-7
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 4.644291e-7
GO:0009612 response to mechanical stimulus 5.158084e-7
GO:0060117 auditory receptor cell development 5.546260e-7
GO:0000105 histidine biosynthetic process 5.842807e-7
GO:0002312 B cell activation involved in immune response 5.945128e-7
GO:0007608 sensory perception of smell 6.008543e-7
GO:0050906 detection of stimulus involved in sensory perception 6.445092e-7
GO:0030098 lymphocyte differentiation 7.045268e-7
GO:0042135 neurotransmitter catabolic process 7.230848e-7
GO:0006790 sulfur compound metabolic process 7.546512e-7
GO:0044003 modification by symbiont of host morphology or physiology 8.101352e-7
GO:0070227 lymphocyte apoptosis 1.021732e-6
GO:0060041 retina development in camera-type eye 1.175072e-6
GO:0009063 cellular amino acid catabolic process 1.187588e-6
GO:0050878 regulation of body fluid levels 1.205127e-6
GO:0001654 eye development 1.250288e-6
GO:0031623 receptor internalization 1.269654e-6
GO:0002702 positive regulation of production of molecular mediator of immune response 1.314803e-6
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 1.325593e-6
GO:0048240 sperm capacitation 1.398315e-6
GO:0009611 response to wounding 1.411510e-6
GO:0021537 telencephalon development 1.424164e-6
GO:0043056 forward locomotion 1.427947e-6
GO:0003333 amino acid transmembrane transport 1.441984e-6
GO:0042440 pigment metabolic process 1.558771e-6
GO:0006898 receptor-mediated endocytosis 1.609259e-6
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 1.658618e-6
GO:0050867 positive regulation of cell activation 1.668061e-6
GO:0048512 circadian behavior 1.863981e-6
GO:0045321 leukocyte activation 1.881245e-6
GO:0002700 regulation of production of molecular mediator of immune response 1.911847e-6
GO:0006436 tryptophanyl-tRNA aminoacylation 1.925234e-6
GO:0002683 negative regulation of immune system process 2.015835e-6
GO:0048583 regulation of response to stimulus 2.162652e-6
GO:0045494 photoreceptor cell maintenance 2.306060e-6
GO:0006582 melanin metabolic process 2.316609e-6
GO:0002335 mature B cell differentiation 2.333015e-6
GO:0002376 immune system process 2.616556e-6
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 2.649414e-6
GO:0050776 regulation of immune response 2.972231e-6
GO:0021987 cerebral cortex development 3.096035e-6
GO:0045214 sarcomere organization 3.275132e-6
GO:0006955 immune response 3.393806e-6
GO:0006954 inflammatory response 3.468039e-6
GO:0000103 sulfate assimilation 3.760319e-6
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation 4.615752e-6
GO:0016064 immunoglobulin mediated immune response 5.232301e-6
GO:0042753 positive regulation of circadian rhythm 5.369251e-6
GO:0032438 melanosome organization 5.614832e-6
GO:0002237 response to molecule of bacterial origin 5.677553e-6
GO:0046649 lymphocyte activation 5.713945e-6
GO:0051249 regulation of lymphocyte activation 5.879433e-6
GO:0042759 long-chain fatty acid biosynthetic process 6.107855e-6
GO:0009083 branched chain family amino acid catabolic process 6.189903e-6
GO:0060401 cytosolic calcium ion transport 6.258298e-6
GO:0007411 axon guidance 6.796248e-6
GO:0010507 negative regulation of autophagy 6.829593e-6
GO:0007186 G-protein coupled receptor protein signaling pathway 6.838431e-6
GO:0009396 folic acid-containing compound biosynthetic process 7.105976e-6
GO:0050974 detection of mechanical stimulus involved in sensory perception 7.172534e-6
GO:0045671 negative regulation of osteoclast differentiation 7.200764e-6
GO:0065007 biological regulation 7.220485e-6
GO:0019724 B cell mediated immunity 7.221857e-6
GO:0045582 positive regulation of T cell differentiation 7.311739e-6
GO:0002093 auditory receptor cell morphogenesis 7.597527e-6
GO:0002285 lymphocyte activation involved in immune response 7.775269e-6
GO:0014706 striated muscle tissue development 8.525829e-6
GO:0052547 regulation of peptidase activity 8.720926e-6
GO:0033280 response to vitamin D 8.746336e-6
GO:0051883 killing of cells in other organism involved in symbiotic interaction 9.741977e-6
GO:0032496 response to lipopolysaccharide 9.943303e-6
GO:0060402 calcium ion transport into cytosol 1.041273e-5
GO:0050789 regulation of biological process 1.072000e-5
GO:0040011 locomotion 1.107125e-5
GO:0048738 cardiac muscle tissue development 1.160428e-5
GO:0010466 negative regulation of peptidase activity 1.161447e-5
GO:0070207 protein homotrimerization 1.202341e-5
GO:0048034 heme O biosynthetic process 1.212476e-5
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 1.293944e-5
GO:0045444 fat cell differentiation 1.298559e-5
GO:0031640 killing of cells of other organism 1.299999e-5
GO:0060537 muscle tissue development 1.339808e-5
GO:0042110 T cell activation 1.346997e-5
GO:0042594 response to starvation 1.372599e-5
GO:0048515 spermatid differentiation 1.378989e-5
GO:0006970 response to osmotic stress 1.518345e-5
GO:0048667 cell morphogenesis involved in neuron differentiation 1.568282e-5
GO:0002449 lymphocyte mediated immunity 1.612385e-5
GO:0048856 anatomical structure development 1.650055e-5
GO:0007026 negative regulation of microtubule depolymerization 1.760743e-5
GO:0050982 detection of mechanical stimulus 1.766671e-5
GO:0045926 negative regulation of growth 1.846597e-5
GO:0050670 regulation of lymphocyte proliferation 1.867104e-5
GO:0032332 positive regulation of chondrocyte differentiation 1.989296e-5
GO:0002443 leukocyte mediated immunity 2.030792e-5
GO:0031114 regulation of microtubule depolymerization 2.068292e-5
GO:0070663 regulation of leukocyte proliferation 2.136903e-5
GO:0032944 regulation of mononuclear cell proliferation 2.175008e-5
GO:0045348 positive regulation of MHC class II biosynthetic process 2.181760e-5
GO:0048869 cellular developmental process 2.193008e-5
GO:0006278 RNA-dependent DNA replication 2.246956e-5
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 2.263322e-5
GO:0033058 directional locomotion 2.275983e-5
GO:0042752 regulation of circadian rhythm 2.452297e-5
GO:0006916 anti-apoptosis 2.524434e-5
GO:0050870 positive regulation of T cell activation 2.531111e-5
GO:0030154 cell differentiation 2.546232e-5
GO:0051606 detection of stimulus 2.650965e-5
GO:0043010 camera-type eye development 2.669747e-5
GO:0055002 striated muscle cell development 2.763250e-5
GO:0050808 synapse organization 2.770012e-5
GO:0042060 wound healing 2.939885e-5
GO:0001783 B cell apoptosis 3.055695e-5
GO:0048013 ephrin receptor signaling pathway 3.056059e-5
GO:0003006 developmental process involved in reproduction 3.067009e-5
GO:0007409 axonogenesis 3.092766e-5
GO:0022602 ovulation cycle process 3.106588e-5
GO:0048305 immunoglobulin secretion 3.213683e-5
GO:0001775 cell activation 3.259389e-5
GO:0001503 ossification 3.361201e-5
GO:0006400 tRNA modification 3.479953e-5
GO:0055001 muscle cell development 3.480542e-5
GO:0002329 pre-B cell differentiation 3.486227e-5
GO:0022610 biological adhesion 3.496855e-5
GO:0020028 hemoglobin import 3.626057e-5
GO:0048852 diencephalon morphogenesis 3.695404e-5
GO:0007512 adult heart development 3.730732e-5
GO:0032502 developmental process 3.737987e-5
GO:0051251 positive regulation of lymphocyte activation 3.744008e-5
GO:0032094 response to food 3.874039e-5
GO:0048609 multicellular organismal reproductive process 4.053024e-5
GO:0019748 secondary metabolic process 4.075701e-5
GO:0032800 receptor biosynthetic process 4.135480e-5
GO:0007622 rhythmic behavior 4.171140e-5
GO:0050863 regulation of T cell activation 4.288941e-5
GO:0060088 auditory receptor cell stereocilium organization 4.396833e-5
GO:0051239 regulation of multicellular organismal process 4.539056e-5
GO:2000026 regulation of multicellular organismal development 4.560866e-5
GO:0030239 myofibril assembly 4.696617e-5
GO:0043900 regulation of multi-organism process 4.710741e-5
GO:0042113 B cell activation 4.840306e-5
GO:0090199 regulation of release of cytochrome c from mitochondria 4.840552e-5
GO:0071985 multivesicular body sorting pathway 4.862638e-5
GO:0006520 cellular amino acid metabolic process 4.900920e-5
GO:0051961 negative regulation of nervous system development 5.036654e-5
GO:0048753 pigment granule organization 5.304878e-5
GO:0071496 cellular response to external stimulus 5.352095e-5
GO:0006935 chemotaxis 5.681455e-5
GO:0050777 negative regulation of immune response 6.001112e-5
GO:0045668 negative regulation of osteoblast differentiation 6.093632e-5
GO:0042402 cellular biogenic amine catabolic process 6.643859e-5
GO:0010033 response to organic substance 6.665894e-5
GO:0055013 cardiac muscle cell development 6.757602e-5
GO:0030502 negative regulation of bone mineralization 6.784067e-5
GO:0070168 negative regulation of biomineral tissue development 6.823137e-5
GO:0006082 organic acid metabolic process 7.180200e-5
GO:0050953 sensory perception of light stimulus 7.290414e-5
GO:0050794 regulation of cellular process 7.350270e-5
GO:0060632 regulation of microtubule-based movement 7.473782e-5
GO:0042180 cellular ketone metabolic process 7.707861e-5
GO:0031032 actomyosin structure organization 7.911338e-5
GO:0006865 amino acid transport 7.954361e-5
GO:0046013 regulation of T cell homeostatic proliferation 7.989977e-5
GO:0009582 detection of abiotic stimulus 8.092809e-5
GO:0042330 taxis 8.098733e-5
GO:0019374 galactolipid metabolic process 8.154843e-5
GO:0043480 pigment accumulation in tissues 8.172306e-5
GO:0015837 amine transport 8.357947e-5
GO:0006928 cellular component movement 8.378061e-5
GO:0046689 response to mercury ion 8.694155e-5
GO:0035058 nonmotile primary cilium assembly 8.834669e-5
GO:0007494 midgut development 9.042724e-5
GO:0007601 visual perception 9.189329e-5
GO:0002315 marginal zone B cell differentiation 9.374038e-5
GO:0022603 regulation of anatomical structure morphogenesis 9.543202e-5
GO:0050850 positive regulation of calcium-mediated signaling 9.552900e-5
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 9.610834e-5
GO:0016192 vesicle-mediated transport 9.612297e-5
GO:0019752 carboxylic acid metabolic process 9.827019e-5
GO:0032989 cellular component morphogenesis 9.888765e-5
GO:0046148 pigment biosynthetic process 9.962684e-5
GO:0045137 development of primary sexual characteristics 9.967754e-5
GO:0019376 galactolipid catabolic process 1.036320e-4
GO:0008283 cell proliferation 1.065126e-4
GO:0009081 branched chain family amino acid metabolic process 1.074635e-4
GO:0042403 thyroid hormone metabolic process 1.099929e-4
GO:0007155 cell adhesion 1.100034e-4
GO:0048854 brain morphogenesis 1.113819e-4
GO:0048534 hemopoietic or lymphoid organ development 1.144581e-4
GO:0006787 porphyrin-containing compound catabolic process 1.169032e-4
GO:0030308 negative regulation of cell growth 1.206044e-4
GO:0045765 regulation of angiogenesis 1.220754e-4
GO:0031111 negative regulation of microtubule polymerization or depolymerization 1.228243e-4
GO:0043112 receptor metabolic process 1.266351e-4
GO:0043206 fibril organization 1.277429e-4
GO:0071705 nitrogen compound transport 1.287335e-4
GO:0051646 mitochondrion localization 1.305272e-4
GO:0009308 amine metabolic process 1.326538e-4
GO:0070665 positive regulation of leukocyte proliferation 1.334535e-4
GO:0030910 olfactory placode formation 1.371142e-4
GO:0019098 reproductive behavior 1.396141e-4
GO:0006897 endocytosis 1.398242e-4
GO:0002637 regulation of immunoglobulin production 1.463480e-4
GO:0042554 superoxide anion generation 1.497050e-4
GO:0009966 regulation of signal transduction 1.508080e-4
GO:0002262 myeloid cell homeostasis 1.515334e-4
GO:0042628 mating plug formation 1.556115e-4
GO:0002768 immune response-regulating cell surface receptor signaling pathway 1.581266e-4
GO:0033363 secretory granule organization 1.594973e-4
GO:2000353 positive regulation of endothelial cell apoptosis 1.618381e-4
GO:0015860 purine nucleoside transport 1.618381e-4
GO:0021543 pallium development 1.633505e-4
GO:0006958 complement activation, classical pathway 1.649840e-4
GO:0051179 localization 1.654155e-4
GO:0050854 regulation of antigen receptor-mediated signaling pathway 1.693704e-4
GO:0051964 negative regulation of synapse assembly 1.721191e-4
GO:0050671 positive regulation of lymphocyte proliferation 1.731426e-4
GO:0007017 microtubule-based process 1.733165e-4
GO:0002520 immune system development 1.807062e-4
GO:0043954 cellular component maintenance 1.855727e-4
GO:0060736 prostate gland growth 1.902586e-4
GO:0006968 cellular defense response 1.977011e-4
GO:0035645 enteric smooth muscle cell differentiation 1.982626e-4
GO:0007497 posterior midgut development 1.982626e-4
GO:0002831 regulation of response to biotic stimulus 2.015718e-4
GO:0032836 glomerular basement membrane development 2.022439e-4
GO:0042698 ovulation cycle 2.024697e-4
GO:0032946 positive regulation of mononuclear cell proliferation 2.029671e-4
GO:0030097 hemopoiesis 2.050432e-4
GO:0050708 regulation of protein secretion 2.055817e-4
GO:0008406 gonad development 2.155145e-4
GO:0035458 cellular response to interferon-beta 2.158792e-4
GO:0071732 cellular response to nitric oxide 2.158792e-4
GO:0000003 reproduction 2.181383e-4
GO:0040008 regulation of growth 2.189164e-4
GO:0032330 regulation of chondrocyte differentiation 2.214453e-4
GO:0007416 synapse assembly 2.226143e-4
GO:0045766 positive regulation of angiogenesis 2.273862e-4
GO:0002366 leukocyte activation involved in immune response 2.273862e-4
GO:0021629 olfactory nerve structural organization 2.322571e-4
GO:0010957 negative regulation of vitamin D biosynthetic process 2.322571e-4
GO:0030316 osteoclast differentiation 2.322914e-4
GO:0001706 endoderm formation 2.343551e-4
GO:0060119 inner ear receptor cell development 2.347999e-4
GO:0002720 positive regulation of cytokine production involved in immune response 2.347999e-4
GO:0051240 positive regulation of multicellular organismal process 2.377968e-4
GO:0048563 post-embryonic organ morphogenesis 2.429725e-4
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway 2.429725e-4
GO:0009267 cellular response to starvation 2.433632e-4
GO:0030888 regulation of B cell proliferation 2.486701e-4
GO:0048841 regulation of axon extension involved in axon guidance 2.537918e-4
GO:0048843 negative regulation of axon extension involved in axon guidance 2.589593e-4
GO:0023051 regulation of signaling 2.600716e-4
GO:0071842 cellular component organization at cellular level 2.600972e-4
GO:0031669 cellular response to nutrient levels 2.603428e-4
GO:2000351 regulation of endothelial cell apoptosis 2.612049e-4
GO:0009266 response to temperature stimulus 2.661423e-4
GO:0022414 reproductive process 2.695577e-4
GO:0007167 enzyme linked receptor protein signaling pathway 2.720599e-4
GO:0009653 anatomical structure morphogenesis 2.779717e-4
GO:0032102 negative regulation of response to external stimulus 2.826803e-4
GO:0030517 negative regulation of axon extension 2.848649e-4
GO:0002360 T cell lineage commitment 2.862173e-4
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 2.888860e-4
GO:0048511 rhythmic process 2.909258e-4
GO:0006583 melanin biosynthetic process from tyrosine 2.973336e-4
GO:0061024 membrane organization 2.974758e-4
GO:0032886 regulation of microtubule-based process 2.980680e-4
GO:0090200 positive regulation of release of cytochrome c from mitochondria 2.992843e-4
GO:0006686 sphingomyelin biosynthetic process 2.992843e-4
GO:0032880 regulation of protein localization 3.027423e-4
GO:0007283 spermatogenesis 3.079539e-4
GO:0006885 regulation of pH 3.129662e-4
GO:0060741 prostate gland stromal morphogenesis 3.157824e-4
GO:0009082 branched chain family amino acid biosynthetic process 3.182929e-4
GO:0030212 hyaluronan metabolic process 3.203004e-4
GO:0060751 branch elongation involved in mammary gland duct branching 3.332083e-4
GO:0051454 intracellular pH elevation 3.372427e-4
GO:0072592 oxygen metabolic process 3.372427e-4
GO:0010817 regulation of hormone levels 3.410835e-4
GO:0030260 entry into host cell 3.413505e-4
GO:0046395 carboxylic acid catabolic process 3.468561e-4
GO:0010894 negative regulation of steroid biosynthetic process 3.515638e-4
GO:0051346 negative regulation of hydrolase activity 3.521456e-4
GO:0006643 membrane lipid metabolic process 3.550389e-4
GO:0060068 vagina development 3.579274e-4
GO:0000238 zygotene 3.639328e-4
GO:0035106 operant conditioning 3.639328e-4
GO:0051234 establishment of localization 3.667168e-4
GO:0050793 regulation of developmental process 3.682667e-4
GO:0048731 system development 3.706750e-4
GO:0016044 cellular membrane organization 3.774467e-4
GO:0032509 endosome transport via multivesicular body sorting pathway 3.809244e-4
GO:2000177 regulation of neural precursor cell proliferation 3.875154e-4
GO:0030217 T cell differentiation 3.903204e-4
GO:0061039 ovum-producing ovary development 3.906975e-4
GO:0002833 positive regulation of response to biotic stimulus 3.920203e-4
GO:0032464 positive regulation of protein homooligomerization 3.941752e-4
GO:0021843 substrate-independent telencephalic tangential interneuron migration 3.945115e-4
GO:0051146 striated muscle cell differentiation 3.985720e-4
GO:0042404 thyroid hormone catabolic process 4.159422e-4
GO:0032526 response to retinoic acid 4.473641e-4
GO:0051659 maintenance of mitochondrion location 4.495806e-4
GO:0007623 circadian rhythm 4.506078e-4
GO:0051336 regulation of hydrolase activity 4.533239e-4
GO:0045541 negative regulation of cholesterol biosynthetic process 4.551747e-4
GO:0035644 phosphoanandamide dephosphorylation 4.551747e-4
GO:0045767 regulation of anti-apoptosis 4.553409e-4
GO:0032200 telomere organization 4.560749e-4
GO:0048521 negative regulation of behavior 4.659708e-4
GO:0016445 somatic diversification of immunoglobulins 4.704272e-4
GO:0001919 regulation of receptor recycling 4.710093e-4
GO:0016553 base conversion or substitution editing 4.889709e-4
GO:0006972 hyperosmotic response 4.897070e-4
GO:0009593 detection of chemical stimulus 4.913024e-4
GO:0043252 sodium-independent organic anion transport 4.928727e-4
GO:0016078 tRNA catabolic process 4.928727e-4
GO:0001682 tRNA 5'-leader removal 4.928727e-4
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA 4.928727e-4
GO:0060154 cellular process regulating host cell cycle in response to virus 4.942657e-4
GO:0034198 cellular response to amino acid starvation 5.012433e-4
GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis 5.012433e-4
GO:0051657 maintenance of organelle location 5.078607e-4
GO:0045346 regulation of MHC class II biosynthetic process 5.141710e-4
GO:0051701 interaction with host 5.380635e-4
GO:0009181 purine ribonucleoside diphosphate catabolic process 5.401574e-4
GO:0010035 response to inorganic substance 5.430008e-4
GO:0006022 aminoglycan metabolic process 5.431661e-4
GO:0032878 regulation of establishment or maintenance of cell polarity 5.597876e-4
GO:0070201 regulation of establishment of protein localization 5.678884e-4
GO:0007157 heterophilic cell-cell adhesion 5.769508e-4
GO:0035815 positive regulation of renal sodium excretion 5.830241e-4
GO:0048385 regulation of retinoic acid receptor signaling pathway 5.853878e-4
GO:0048518 positive regulation of biological process 5.928388e-4
GO:0055006 cardiac cell development 5.974776e-4
GO:0033189 response to vitamin A 5.975667e-4
GO:0051917 regulation of fibrinolysis 6.059202e-4
GO:0045619 regulation of lymphocyte differentiation 6.092870e-4
GO:0014043 negative regulation of neuron maturation 6.152628e-4
GO:0050864 regulation of B cell activation 6.190065e-4
GO:0033687 osteoblast proliferation 6.199867e-4
GO:0048640 negative regulation of developmental growth 6.271816e-4
GO:0001701 in utero embryonic development 6.326361e-4
GO:0043901 negative regulation of multi-organism process 6.437933e-4
GO:0042167 heme catabolic process 6.460741e-4
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 6.460741e-4
GO:0048145 regulation of fibroblast proliferation 6.474175e-4
GO:0000723 telomere maintenance 6.497857e-4
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 6.518294e-4
GO:0060122 inner ear receptor stereocilium organization 6.547037e-4
GO:0051668 localization within membrane 6.626747e-4
GO:0045588 positive regulation of gamma-delta T cell differentiation 6.727367e-4
GO:0006637 acyl-CoA metabolic process 6.727367e-4
GO:0046548 retinal rod cell development 6.800610e-4
GO:0034103 regulation of tissue remodeling 6.826143e-4
GO:0003008 system process 6.875487e-4
GO:0002695 negative regulation of leukocyte activation 6.900060e-4
GO:0006784 heme a biosynthetic process 6.913523e-4
GO:0050848 regulation of calcium-mediated signaling 7.060382e-4
GO:0001906 cell killing 7.190702e-4
GO:0045580 regulation of T cell differentiation 7.220985e-4
GO:0022010 central nervous system myelination 7.231455e-4
GO:0009306 protein secretion 7.294047e-4
GO:0033152 immunoglobulin V(D)J recombination 7.348210e-4
GO:0044281 small molecule metabolic process 7.378488e-4
GO:0043242 negative regulation of protein complex disassembly 7.387367e-4
GO:0033273 response to vitamin 7.468610e-4
GO:0010038 response to metal ion 7.529237e-4
GO:0050778 positive regulation of immune response 7.663396e-4
GO:0014904 myotube cell development 7.678873e-4
GO:0016447 somatic recombination of immunoglobulin gene segments 7.691377e-4
GO:0044106 cellular amine metabolic process 7.804710e-4
GO:0045332 phospholipid translocation 7.903137e-4
GO:0006959 humoral immune response 8.067837e-4
GO:0046545 development of primary female sexual characteristics 8.108510e-4
GO:0034341 response to interferon-gamma 8.117460e-4
GO:0009408 response to heat 8.140666e-4
GO:0002429 immune response-activating cell surface receptor signaling pathway 8.274840e-4
GO:0051223 regulation of protein transport 8.346839e-4
GO:2000741 positive regulation of mesenchymal stem cell differentiation 8.443448e-4
GO:0002358 B cell homeostatic proliferation 8.483037e-4
GO:0015805 S-adenosylmethionine transport 8.584947e-4
GO:0050790 regulation of catalytic activity 8.594122e-4
GO:0043406 positive regulation of MAP kinase activity 8.603972e-4
GO:0034201 response to oleic acid 8.694936e-4
GO:0019439 aromatic compound catabolic process 8.812247e-4
GO:0046627 negative regulation of insulin receptor signaling pathway 8.888118e-4
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 9.001763e-4
GO:0048468 cell development 9.011721e-4
GO:0032653 regulation of interleukin-10 production 9.058346e-4
GO:0042448 progesterone metabolic process 9.116123e-4
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 9.148069e-4
GO:0038027 apolipoprotein A-I-mediated signaling pathway 9.512807e-4
GO:0042938 dipeptide transport 9.512807e-4
GO:0033598 mammary gland epithelial cell proliferation 9.526298e-4
GO:2000179 positive regulation of neural precursor cell proliferation 9.540661e-4
GO:0006911 phagocytosis, engulfment 9.568826e-4
GO:0045591 positive regulation of regulatory T cell differentiation 9.577591e-4
GO:0045597 positive regulation of cell differentiation 9.592771e-4
GO:0050851 antigen receptor-mediated signaling pathway 9.662954e-4
GO:0001649 osteoblast differentiation 9.741156e-4
GO:0002250 adaptive immune response 9.742825e-4
GO:0048592 eye morphogenesis 9.757494e-4
GO:0033364 mast cell secretory granule organization 9.804714e-4
GO:0000733 DNA strand renaturation 9.804714e-4
GO:0071879 positive regulation of adrenergic receptor signaling pathway 9.872089e-4
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 9.872089e-4
GO:0010821 regulation of mitochondrion organization 9.906239e-4
GO:0046110 xanthine metabolic process 9.928161e-4
GO:0035129 post-embryonic hindlimb morphogenesis 1.007020e-3
GO:0042219 cellular modified amino acid catabolic process 1.013260e-3
GO:0051250 negative regulation of lymphocyte activation 1.023782e-3
GO:0008585 female gonad development 1.023782e-3
GO:0090287 regulation of cellular response to growth factor stimulus 1.025527e-3
GO:0071305 cellular response to vitamin D 1.031088e-3
GO:0046209 nitric oxide metabolic process 1.031088e-3
GO:0032675 regulation of interleukin-6 production 1.041178e-3
GO:0050866 negative regulation of cell activation 1.056882e-3
GO:0048608 reproductive structure development 1.060617e-3
GO:0051856 adhesion to symbiont 1.073854e-3
GO:0060042 retina morphogenesis in camera-type eye 1.083706e-3
GO:0043064 flagellum organization 1.091618e-3
GO:0043623 cellular protein complex assembly 1.096131e-3
GO:0045065 cytotoxic T cell differentiation 1.104127e-3
GO:0051023 regulation of immunoglobulin secretion 1.133064e-3
GO:0032733 positive regulation of interleukin-10 production 1.142882e-3
GO:0010575 positive regulation vascular endothelial growth factor production 1.143564e-3
GO:0033865 nucleoside bisphosphate metabolic process 1.143633e-3
GO:0048812 neuron projection morphogenesis 1.148563e-3
GO:0050856 regulation of T cell receptor signaling pathway 1.163779e-3
GO:0006810 transport 1.184813e-3
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 1.193550e-3
GO:0045401 positive regulation of interleukin-3 biosynthetic process 1.193550e-3
GO:0050973 detection of mechanical stimulus involved in equilibrioception 1.226422e-3
GO:0007275 multicellular organismal development 1.253759e-3
GO:0090174 organelle membrane fusion 1.259745e-3