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Novel motif:42

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name:motif42_CGNTCA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0006481 C-terminal protein methylation 7.998625e-10
GO:0031929 TOR signaling cascade 8.343789e-8
GO:0051313 attachment of spindle microtubules to chromosome 9.489041e-8
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 1.125278e-7
GO:0006369 termination of RNA polymerase II transcription 1.250812e-7
GO:0010836 negative regulation of protein ADP-ribosylation 3.119637e-7
GO:0042149 cellular response to glucose starvation 3.932530e-7
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 8.014499e-7
GO:0000387 spliceosomal snRNP assembly 1.293966e-6
GO:0043503 skeletal muscle fiber adaptation 1.339861e-6
GO:0007021 tubulin complex assembly 1.610496e-6
GO:0072668 tubulin complex biogenesis 2.176417e-6
GO:0060017 parathyroid gland development 4.931050e-6
GO:0010625 positive regulation of Schwann cell proliferation 5.665798e-6
GO:0000296 spermine transport 5.683164e-6
GO:0031468 nuclear envelope reassembly 5.691087e-6
GO:0072268 pattern specification involved in metanephros development 6.680332e-6
GO:0006534 cysteine metabolic process 6.937638e-6
GO:0006364 rRNA processing 7.465565e-6
GO:0002769 natural killer cell inhibitory signaling pathway 7.997172e-6
GO:0032926 negative regulation of activin receptor signaling pathway 9.682684e-6
GO:0016072 rRNA metabolic process 9.824884e-6
GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity 1.242270e-5
GO:0006600 creatine metabolic process 1.851806e-5
GO:0002431 Fc receptor mediated stimulatory signaling pathway 1.897100e-5
GO:0001805 positive regulation of type III hypersensitivity 1.897100e-5
GO:0097029 mature dendritic cell differentiation 2.139660e-5
GO:0060977 coronary vasculature morphogenesis 2.162981e-5
GO:0042503 tyrosine phosphorylation of Stat3 protein 2.317316e-5
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 2.369773e-5
GO:0032769 negative regulation of monooxygenase activity 2.712241e-5
GO:0002861 regulation of inflammatory response to antigenic stimulus 3.138533e-5
GO:0002036 regulation of L-glutamate transport 3.206625e-5
GO:0044140 negative regulation of growth of symbiont on or near host surface 3.296437e-5
GO:0000414 regulation of histone H3-K36 methylation 3.792895e-5
GO:0010624 regulation of Schwann cell proliferation 3.890670e-5
GO:0061015 snRNA import into nucleus 3.982039e-5
GO:0006868 glutamine transport 5.059592e-5
GO:0046813 virion attachment, binding of host cell surface receptor 6.280461e-5
GO:0008054 cyclin catabolic process 6.860684e-5
GO:0071421 manganese ion transmembrane transport 7.165429e-5
GO:0000389 nuclear mRNA 3'-splice site recognition 7.165429e-5
GO:0006447 regulation of translational initiation by iron 7.546016e-5
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 7.885125e-5
GO:0060058 positive regulation of apoptosis involved in mammary gland involution 8.280190e-5
GO:0009070 serine family amino acid biosynthetic process 9.009246e-5
GO:0043088 regulation of Cdc42 GTPase activity 9.011434e-5
GO:0042506 tyrosine phosphorylation of Stat5 protein 9.346772e-5
GO:0014829 vascular smooth muscle contraction 9.687208e-5
GO:0070544 histone H3-K36 demethylation 9.750702e-5
GO:0043587 tongue morphogenesis 1.017182e-4
GO:0003218 cardiac left ventricle formation 1.039717e-4
GO:0060695 negative regulation of cholesterol transporter activity 1.098996e-4
GO:0070194 synaptonemal complex disassembly 1.166189e-4
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 1.166189e-4
GO:0008608 attachment of spindle microtubules to kinetochore 1.210474e-4
GO:0019344 cysteine biosynthetic process 1.211706e-4
GO:0009069 serine family amino acid metabolic process 1.268907e-4
GO:0006432 phenylalanyl-tRNA aminoacylation 1.274827e-4
GO:0021658 rhombomere 3 morphogenesis 1.397101e-4
GO:0014740 negative regulation of muscle hyperplasia 1.542898e-4
GO:0014888 striated muscle adaptation 1.569407e-4
GO:0007422 peripheral nervous system development 1.584031e-4
GO:0001710 mesodermal cell fate commitment 1.598154e-4
GO:0051764 actin crosslink formation 1.653489e-4
GO:0060356 leucine import 1.774854e-4
GO:0030644 cellular chloride ion homeostasis 1.775892e-4
GO:0003329 pancreatic PP cell fate commitment 1.808802e-4
GO:0003326 pancreatic A cell fate commitment 1.808802e-4
GO:0070814 hydrogen sulfide biosynthetic process 1.935285e-4
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.953373e-4
GO:0016340 calcium-dependent cell-matrix adhesion 2.040726e-4
GO:0000398 nuclear mRNA splicing, via spliceosome 2.088568e-4
GO:0048280 vesicle fusion with Golgi apparatus 2.097897e-4
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 2.258101e-4
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 2.296836e-4
GO:0021895 cerebral cortex neuron differentiation 2.416787e-4
GO:0072179 nephric duct formation 2.452633e-4
GO:0043501 skeletal muscle adaptation 2.458098e-4
GO:0043491 protein kinase B signaling cascade 2.576128e-4
GO:0033342 negative regulation of collagen binding 2.622091e-4
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 2.622091e-4
GO:0009589 detection of UV 2.622091e-4
GO:0003148 outflow tract septum morphogenesis 2.667608e-4
GO:0008380 RNA splicing 2.689319e-4
GO:0040040 thermosensory behavior 2.722947e-4
GO:0021530 spinal cord oligodendrocyte cell fate specification 2.722947e-4
GO:0051299 centrosome separation 3.084191e-4
GO:0050685 positive regulation of mRNA processing 3.125728e-4
GO:0022038 corpus callosum development 3.316074e-4
GO:0050667 homocysteine metabolic process 3.370696e-4
GO:0051457 maintenance of protein location in nucleus 3.713470e-4
GO:0072176 nephric duct development 3.737686e-4
GO:0060252 positive regulation of glial cell proliferation 3.913361e-4
GO:0072178 nephric duct morphogenesis 4.204488e-4
GO:0046796 viral genome transport in host cell 4.257581e-4
GO:0051205 protein insertion into membrane 4.466020e-4
GO:0051955 regulation of amino acid transport 4.551356e-4
GO:0003221 right ventricular cardiac muscle tissue morphogenesis 4.632164e-4
GO:0030277 maintenance of gastrointestinal epithelium 4.709759e-4
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 4.746038e-4
GO:0000375 RNA splicing, via transesterification reactions 4.852674e-4
GO:0001812 positive regulation of type I hypersensitivity 4.874073e-4
GO:0002885 positive regulation of hypersensitivity 4.882229e-4
GO:2000195 negative regulation of female gonad development 4.936341e-4
GO:0021892 cerebral cortex GABAergic interneuron differentiation 5.396603e-4
GO:0014002 astrocyte development 5.547211e-4
GO:0070141 response to UV-A 5.675822e-4
GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation 5.743175e-4
GO:2000194 regulation of female gonad development 6.081873e-4
GO:0042254 ribosome biogenesis 6.168216e-4
GO:0035767 endothelial cell chemotaxis 6.208611e-4
GO:0043418 homocysteine catabolic process 6.379034e-4
GO:0061157 mRNA destabilization 6.379034e-4
GO:0019346 transsulfuration 6.379034e-4
GO:0010609 posttranscriptional regulation of gene expression by mRNA localization 6.379034e-4
GO:0006478 peptidyl-tyrosine sulfation 6.379034e-4
GO:0006535 cysteine biosynthetic process from serine 6.379034e-4
GO:0019343 cysteine biosynthetic process via cystathionine 6.379034e-4
GO:0034214 protein hexamerization 6.379504e-4
GO:2001037 positive regulation of tongue muscle cell differentiation 6.402081e-4
GO:0097152 mesenchymal cell apoptosis 6.402081e-4
GO:0060982 coronary artery morphogenesis 6.402081e-4
GO:0006844 acyl carnitine transport 6.618881e-4
GO:0008334 histone mRNA metabolic process 6.647063e-4
GO:0060620 regulation of cholesterol import 6.826938e-4
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 7.617982e-4
GO:0021869 forebrain ventricular zone progenitor cell division 7.709481e-4
GO:0002037 negative regulation of L-glutamate transport 7.724054e-4
GO:0045994 positive regulation of translational initiation by iron 7.724054e-4
GO:0021954 central nervous system neuron development 7.747934e-4
GO:0000415 negative regulation of histone H3-K36 methylation 8.474882e-4
GO:0048203 vesicle targeting, trans-Golgi to endosome 8.560100e-4
GO:0031023 microtubule organizing center organization 9.016996e-4
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 9.089352e-4
GO:0007198 inhibition of adenylate cyclase activity by serotonin receptor signaling pathway 9.398048e-4
GO:0015761 mannose transport 9.398048e-4
GO:0006425 glutaminyl-tRNA aminoacylation 9.398048e-4
GO:0060534 trachea cartilage development 9.474918e-4
GO:0042508 tyrosine phosphorylation of Stat1 protein 9.688493e-4
GO:0070574 cadmium ion transmembrane transport 9.707680e-4
GO:0022613 ribonucleoprotein complex biogenesis 9.769768e-4
GO:0021528 commissural neuron differentiation in spinal cord 9.885217e-4
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development 9.885217e-4
GO:0003061 positive regulation of the force of heart contraction by norepinephrine 9.885217e-4
GO:0051956 negative regulation of amino acid transport 1.034135e-3
GO:0046500 S-adenosylmethionine metabolic process 1.046085e-3
GO:0035883 enteroendocrine cell differentiation 1.075395e-3
GO:0048790 maintenance of presynaptic active zone structure 1.091874e-3
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 1.091874e-3
GO:0006379 mRNA cleavage 1.112634e-3
GO:0019264 glycine biosynthetic process from serine 1.113347e-3
GO:0000917 barrier septum formation 1.140343e-3
GO:0060020 Bergmann glial cell differentiation 1.175422e-3
GO:0051572 negative regulation of histone H3-K4 methylation 1.207469e-3
GO:0006626 protein targeting to mitochondrion 1.210529e-3
GO:0014738 regulation of muscle hyperplasia 1.214318e-3
GO:0009167 purine ribonucleoside monophosphate metabolic process 1.271767e-3
GO:0006635 fatty acid beta-oxidation 1.274011e-3
GO:0090305 nucleic acid phosphodiester bond hydrolysis 1.279696e-3
GO:0006853 carnitine shuttle 1.281065e-3
GO:0006984 ER-nucleus signaling pathway 1.288719e-3
GO:0034660 ncRNA metabolic process 1.341469e-3
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1.368210e-3
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 1.374723e-3
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1.379028e-3
GO:0006545 glycine biosynthetic process 1.417112e-3
GO:0043089 positive regulation of Cdc42 GTPase activity 1.446109e-3
GO:0022007 convergent extension involved in neural plate elongation 1.476350e-3
GO:0006423 cysteinyl-tRNA aminoacylation 1.506608e-3
GO:0014037 Schwann cell differentiation 1.577073e-3
GO:0006656 phosphatidylcholine biosynthetic process 1.609438e-3
GO:0072655 establishment of protein localization in mitochondrion 1.611345e-3
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 1.655448e-3
GO:0001798 positive regulation of type IIa hypersensitivity 1.679172e-3
GO:0006657 CDP-choline pathway 1.679707e-3
GO:0070407 oxidation-dependent protein catabolic process 1.683261e-3
GO:0061050 regulation of cell growth involved in cardiac muscle cell development 1.724978e-3
GO:0051297 centrosome organization 1.735828e-3
GO:0032526 response to retinoic acid 1.738568e-3
GO:0000380 alternative nuclear mRNA splicing, via spliceosome 1.757603e-3
GO:0051354 negative regulation of oxidoreductase activity 1.896291e-3
GO:0035305 negative regulation of dephosphorylation 1.990619e-3
GO:0061101 neuroendocrine cell differentiation 2.005748e-3
GO:0000185 activation of MAPKKK activity 2.017923e-3
GO:0016598 protein arginylation 2.040998e-3
GO:0035966 response to topologically incorrect protein 2.048233e-3
GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 2.220741e-3
GO:0070585 protein localization in mitochondrion 2.230471e-3
GO:0031442 positive regulation of mRNA 3'-end processing 2.246759e-3
GO:0045007 depurination 2.258033e-3
GO:0032365 intracellular lipid transport 2.259824e-3
GO:0060659 nipple sheath formation 2.260973e-3
GO:0060649 mammary gland bud elongation 2.260973e-3
GO:0032211 negative regulation of telomere maintenance via telomerase 2.265487e-3
GO:0071318 cellular response to ATP 2.316361e-3
GO:0060621 negative regulation of cholesterol import 2.332510e-3
GO:0006398 histone mRNA 3'-end processing 2.332510e-3
GO:0007141 male meiosis I 2.452921e-3
GO:0045835 negative regulation of meiosis 2.452921e-3
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 2.492747e-3
GO:0034384 high-density lipoprotein particle clearance 2.531108e-3
GO:0019448 L-cysteine catabolic process 2.658220e-3
GO:0050689 negative regulation of defense response to virus by host 2.658220e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 2.670222e-3
GO:0090083 regulation of inclusion body assembly 2.731066e-3
GO:0000089 mitotic metaphase 2.731066e-3
GO:0006285 base-excision repair, AP site formation 2.756802e-3
GO:0051793 medium-chain fatty acid catabolic process 2.800974e-3
GO:0042780 tRNA 3'-end processing 2.800974e-3
GO:0023035 CD40 signaling pathway 2.800974e-3
GO:0019062 virion attachment to host cell surface receptor 2.833530e-3
GO:0014745 negative regulation of muscle adaptation 2.834897e-3
GO:0046939 nucleotide phosphorylation 3.002666e-3
GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport 3.069730e-3
GO:0021985 neurohypophysis development 3.069730e-3
GO:0019478 D-amino acid catabolic process 3.070815e-3
GO:0002438 acute inflammatory response to antigenic stimulus 3.070815e-3
GO:0032202 telomere assembly 3.188533e-3
GO:0090086 negative regulation of protein deubiquitination 3.286184e-3
GO:0001958 endochondral ossification 3.342188e-3
GO:0006760 folic acid-containing compound metabolic process 3.347199e-3
GO:0032099 negative regulation of appetite 3.356602e-3
GO:0016197 endosome transport 3.383108e-3
GO:0071843 cellular component biogenesis at cellular level 3.387245e-3
GO:0021666 rhombomere 5 formation 3.444092e-3
GO:0021660 rhombomere 3 formation 3.444092e-3
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 3.447916e-3
GO:0046655 folic acid metabolic process 3.479070e-3
GO:0051001 negative regulation of nitric-oxide synthase activity 3.498523e-3
GO:0030073 insulin secretion 3.538190e-3
GO:0060976 coronary vasculature development 3.631848e-3
GO:0006457 protein folding 3.634346e-3
GO:0071584 negative regulation of zinc ion import 3.674908e-3
GO:0090281 negative regulation of calcium ion import 3.674908e-3
GO:0051791 medium-chain fatty acid metabolic process 3.674908e-3
GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process 3.674908e-3
GO:0032915 positive regulation of transforming growth factor beta2 production 3.674908e-3
GO:0000073 spindle pole body separation 3.674908e-3
GO:0000072 M phase specific microtubule process 3.686237e-3
GO:0002149 hypochlorous acid biosynthetic process 3.706853e-3
GO:0032096 negative regulation of response to food 3.757154e-3
GO:0042558 pteridine-containing compound metabolic process 3.758066e-3
GO:0034470 ncRNA processing 3.777042e-3
GO:0046856 phosphatidylinositol dephosphorylation 3.809457e-3
GO:0002679 respiratory burst involved in defense response 3.850741e-3
GO:0000236 mitotic prometaphase 3.877185e-3
GO:0043951 negative regulation of cAMP-mediated signaling 3.959093e-3
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 3.966046e-3
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 4.009327e-3
GO:0061084 negative regulation of protein refolding 4.012320e-3
GO:0001974 blood vessel remodeling 4.120758e-3
GO:0007260 tyrosine phosphorylation of STAT protein 4.121220e-3
GO:0019086 late viral mRNA transcription 4.165000e-3
GO:0034453 microtubule anchoring 4.198113e-3
GO:0051546 keratinocyte migration 4.315321e-3
GO:0051684 maintenance of Golgi location 4.404528e-3
GO:0045358 negative regulation of interferon-beta biosynthetic process 4.404528e-3
GO:0007029 endoplasmic reticulum organization 4.431562e-3
GO:0055025 positive regulation of cardiac muscle tissue development 4.433286e-3
GO:0007500 mesodermal cell fate determination 4.449302e-3
GO:2000667 positive regulation of interleukin-13 secretion 4.565187e-3
GO:2000665 regulation of interleukin-13 secretion 4.565187e-3
GO:2000703 negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation 4.565187e-3
GO:2000734 negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation 4.565187e-3
GO:2000664 positive regulation of interleukin-5 secretion 4.565187e-3
GO:2000607 negative regulation of cell proliferation involved in mesonephros development 4.565187e-3
GO:2000662 regulation of interleukin-5 secretion 4.565187e-3
GO:0071276 cellular response to cadmium ion 4.566371e-3
GO:0035441 cell migration involved in vasculogenesis 4.607649e-3
GO:0070171 negative regulation of tooth mineralization 4.656821e-3
GO:0033088 negative regulation of immature T cell proliferation in thymus 4.656821e-3
GO:0061103 carotid body glomus cell differentiation 4.657798e-3
GO:0061104 adrenal chromaffin cell differentiation 4.657798e-3
GO:0071259 cellular response to magnetism 4.657798e-3
GO:0061102 stomach neuroendocrine cell differentiation 4.657798e-3
GO:0003359 noradrenergic neuron fate commitment 4.657798e-3
GO:0061100 lung neuroendocrine cell differentiation 4.657798e-3
GO:0060163 subpallium neuron fate commitment 4.657798e-3
GO:0007400 neuroblast fate determination 4.657798e-3
GO:0060165 regulation of timing of subpallium neuron differentiation 4.657798e-3
GO:0021592 fourth ventricle development 4.716736e-3
GO:0072595 maintenance of protein localization to organelle 4.778372e-3
GO:0006839 mitochondrial transport 4.829065e-3
GO:0034505 tooth mineralization 5.086353e-3
GO:0007000 nucleolus organization 5.184415e-3
GO:0046778 modification by virus of host mRNA processing 5.184415e-3
GO:0051642 centrosome localization 5.209748e-3
GO:0006986 response to unfolded protein 5.278498e-3
GO:0002883 regulation of hypersensitivity 5.388822e-3
GO:0034380 high-density lipoprotein particle assembly 5.388822e-3
GO:0018208 peptidyl-proline modification 5.404925e-3
GO:0051953 negative regulation of amine transport 5.448279e-3
GO:0006348 chromatin silencing at telomere 5.491869e-3
GO:0002765 immune response-inhibiting signal transduction 5.491869e-3
GO:0048050 post-embryonic eye morphogenesis 5.703485e-3
GO:0002502 peptide antigen assembly with MHC class I protein complex 5.703485e-3
GO:0061004 pattern specification involved in kidney development 5.755416e-3
GO:0090085 regulation of protein deubiquitination 5.792708e-3
GO:0001732 formation of translation initiation complex 5.937668e-3
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 5.964558e-3
GO:0060350 endochondral bone morphogenesis 5.973655e-3
GO:0051668 localization within membrane 5.989617e-3
GO:0015696 ammonium transport 6.029719e-3
GO:0032374 regulation of cholesterol transport 6.036504e-3
GO:0051929 positive regulation of calcium ion transport via voltage-gated calcium channel activity 6.113618e-3
GO:0006396 RNA processing 6.208340e-3
GO:0006366 transcription from RNA polymerase II promoter 6.220323e-3
GO:0046466 membrane lipid catabolic process 6.264456e-3
GO:0001574 ganglioside biosynthetic process 6.331945e-3
GO:0032812 positive regulation of epinephrine secretion 6.366116e-3
GO:0070253 somatostatin secretion 6.366116e-3
GO:0034162 toll-like receptor 9 signaling pathway 6.366116e-3
GO:2001054 negative regulation of mesenchymal cell apoptosis 6.446211e-3
GO:0009258 10-formyltetrahydrofolate catabolic process 6.446211e-3
GO:0051177 meiotic sister chromatid cohesion 6.446211e-3
GO:0044070 regulation of anion transport 6.506764e-3
GO:0065001 specification of axis polarity 6.523590e-3
GO:0003062 regulation of heart rate by chemical signal 6.523590e-3
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development 6.543954e-3
GO:0000090 mitotic anaphase 6.798372e-3
GO:0006563 L-serine metabolic process 6.920479e-3
GO:0032682 negative regulation of chemokine production 6.962619e-3
GO:0035284 brain segmentation 7.117438e-3
GO:0070076 histone lysine demethylation 7.159931e-3
GO:0048708 astrocyte differentiation 7.230459e-3
GO:0006670 sphingosine metabolic process 7.288507e-3
GO:0006544 glycine metabolic process 7.289142e-3
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine 7.290690e-3
GO:0034446 substrate adhesion-dependent cell spreading 7.366679e-3
GO:0060535 trachea cartilage morphogenesis 7.471763e-3
GO:0030037 actin filament reorganization involved in cell cycle 7.522596e-3
GO:0071294 cellular response to zinc ion 7.540521e-3
GO:0006998 nuclear envelope organization 7.630514e-3
GO:0060291 long-term synaptic potentiation 7.809324e-3
GO:0003016 respiratory system process 7.814432e-3
GO:0043984 histone H4-K16 acetylation 7.824501e-3
GO:0044356 clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine 8.000452e-3
GO:0010835 regulation of protein ADP-ribosylation 8.000452e-3
GO:0010994 free ubiquitin chain polymerization 8.000452e-3
GO:0051580 regulation of neurotransmitter uptake 8.026627e-3
GO:0051322 anaphase 8.069361e-3
GO:0009152 purine ribonucleotide biosynthetic process 8.111964e-3
GO:0002891 positive regulation of immunoglobulin mediated immune response 8.120573e-3
GO:0060014 granulosa cell differentiation 8.170061e-3
GO:0048702 embryonic neurocranium morphogenesis 8.170061e-3
GO:0045987 positive regulation of smooth muscle contraction 8.171302e-3
GO:0070093 negative regulation of glucagon secretion 8.349785e-3
GO:0090245 axis elongation involved in somitogenesis 8.349785e-3
GO:0021874 Wnt receptor signaling pathway involved in forebrain neuroblast division 8.349785e-3
GO:0030262 apoptotic nuclear change 8.363996e-3
GO:0006556 S-adenosylmethionine biosynthetic process 8.501185e-3
GO:0006828 manganese ion transport 8.503691e-3
GO:0018202 peptidyl-histidine modification 8.589338e-3
GO:0006273 lagging strand elongation 8.730096e-3
GO:0032506 cytokinetic process 8.869386e-3
GO:0040001 establishment of mitotic spindle localization 9.030475e-3
GO:0090205 positive regulation of cholesterol metabolic process 9.117102e-3
GO:0001661 conditioned taste aversion 9.117102e-3
GO:0042273 ribosomal large subunit biogenesis 9.186208e-3
GO:0048002 antigen processing and presentation of peptide antigen 9.242605e-3
GO:0090280 positive regulation of calcium ion import 9.300207e-3
GO:0072086 specification of loop of Henle identity 9.300207e-3
GO:0051298 centrosome duplication 9.420967e-3
GO:0021979 hypothalamus cell differentiation 9.428541e-3
GO:2000251 positive regulation of actin cytoskeleton reorganization 9.449491e-3
GO:0021877 forebrain neuron fate commitment 9.451554e-3
GO:0021562 vestibulocochlear nerve development 9.502812e-3
GO:0046340 diacylglycerol catabolic process 9.502812e-3
GO:0021987 cerebral cortex development 9.596522e-3
GO:0060561 apoptosis involved in morphogenesis 9.675298e-3
GO:0072081 specification of nephron tubule identity 9.787782e-3
GO:0034766 negative regulation of ion transmembrane transport 9.877264e-3
GO:0019402 galactitol metabolic process 9.899691e-3
GO:0006564 L-serine biosynthetic process 9.900781e-3
GO:0030149 sphingolipid catabolic process 1.019385e-2
GO:0010159 specification of organ position 1.024035e-2
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 1.032360e-2
GO:0010669 epithelial structure maintenance 1.059912e-2
GO:0031064 negative regulation of histone deacetylation 1.091144e-2
GO:0006173 dADP biosynthetic process 1.094687e-2
GO:0021535 cell migration in hindbrain 1.107329e-2
GO:0045948 positive regulation of translational initiation 1.108956e-2
GO:0032012 regulation of ARF protein signal transduction 1.111909e-2
GO:0042255 ribosome assembly 1.114286e-2
GO:0014044 Schwann cell development 1.118579e-2
GO:0000413 protein peptidyl-prolyl isomerization 1.124692e-2
GO:0006550 isoleucine catabolic process 1.132964e-2
GO:0009098 leucine biosynthetic process 1.132964e-2
GO:0031860 telomeric 3' overhang formation 1.133397e-2
GO:0043456 regulation of pentose-phosphate shunt 1.133397e-2
GO:0009446 putrescine biosynthetic process 1.133397e-2
GO:0018872 arsonoacetate metabolic process 1.133397e-2
GO:0016056 rhodopsin mediated signaling pathway 1.144809e-2
GO:0051585 negative regulation of dopamine uptake 1.174581e-2
GO:0050812 regulation of acyl-CoA biosynthetic process 1.174581e-2
GO:0070495 negative regulation of thrombin receptor signaling pathway 1.174581e-2
GO:0051622 negative regulation of norepinephrine uptake 1.174581e-2
GO:0035881 amacrine cell differentiation 1.174581e-2
GO:0003108 negative regulation of the force of heart contraction by chemical signal 1.174581e-2
GO:0023021 termination of signal transduction 1.174581e-2
GO:0006353 transcription termination, DNA-dependent 1.184728e-2
GO:0060648 mammary gland bud morphogenesis 1.189591e-2
GO:2000143 negative regulation of transcription initiation, DNA-dependent 1.192647e-2
GO:0000416 positive regulation of histone H3-K36 methylation 1.192647e-2
GO:0009153 purine deoxyribonucleotide biosynthetic process 1.195039e-2
GO:0042776 mitochondrial ATP synthesis coupled proton transport 1.197629e-2
GO:0043901 negative regulation of multi-organism process 1.198710e-2
GO:0071529 cementum mineralization 1.202607e-2
GO:0072610 interleukin-12 secretion 1.202607e-2
GO:0002074 extraocular skeletal muscle development 1.202607e-2
GO:0002408 myeloid dendritic cell chemotaxis 1.202607e-2
GO:0010390 histone monoubiquitination 1.210649e-2
GO:0070963 positive regulation of neutrophil mediated killing of gram-negative bacterium 1.218904e-2
GO:0072608 interleukin-10 secretion 1.218904e-2
GO:0090198 negative regulation of chemokine secretion 1.218904e-2
GO:0051660 establishment of centrosome localization 1.218904e-2
GO:0043311 positive regulation of eosinophil degranulation 1.218904e-2
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway 1.218904e-2
GO:0021540 corpus callosum morphogenesis 1.218904e-2
GO:0035926 chemokine (C-C motif) ligand 2 secretion 1.218904e-2
GO:0035646 endosome to melanosome transport 1.221968e-2
GO:0018184 protein polyamination 1.221968e-2
GO:0046359 butyrate catabolic process 1.221968e-2
GO:0016095 polyprenol catabolic process 1.221968e-2
GO:0006272 leading strand elongation 1.221968e-2
GO:0040032 post-embryonic body morphogenesis 1.225224e-2
GO:0016071 mRNA metabolic process 1.247226e-2
GO:0009789 positive regulation of abscisic acid mediated signaling pathway 1.303260e-2
GO:0010870 positive regulation of receptor biosynthetic process 1.326631e-2
GO:0046325 negative regulation of glucose import 1.332586e-2
GO:0071930 negative regulation of transcription involved in G1/S phase of mitotic cell cycle 1.372141e-2
GO:0001771 immunological synapse formation 1.377137e-2
GO:0006406 mRNA export from nucleus 1.386259e-2
GO:0021615 glossopharyngeal nerve morphogenesis 1.396715e-2
GO:0008654 phospholipid biosynthetic process 1.427704e-2
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 1.463398e-2
GO:0051685 maintenance of ER location 1.464632e-2
GO:0030490 maturation of SSU-rRNA 1.465760e-2
GO:0072107 positive regulation of ureteric bud formation 1.474590e-2
GO:0032933 SREBP-mediated signaling pathway 1.484194e-2
GO:0032765 positive regulation of mast cell cytokine production 1.486051e-2
GO:0046165 alcohol biosynthetic process 1.505927e-2
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 1.514276e-2
GO:0033136 serine phosphorylation of STAT3 protein 1.514276e-2
GO:0019348 dolichol metabolic process 1.514276e-2
GO:0035518 histone H2A monoubiquitination 1.515016e-2
GO:0042696 menarche 1.525090e-2
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 1.534877e-2
GO:0061028 establishment of endothelial barrier 1.560168e-2
GO:0015886 heme transport 1.565976e-2
GO:0019987 negative regulation of anti-apoptosis 1.591720e-2
GO:0032008 positive regulation of TOR signaling cascade 1.599458e-2
GO:2000573 positive regulation of DNA biosynthetic process 1.613130e-2
GO:0000093 mitotic telophase 1.613130e-2
GO:0006270 DNA-dependent DNA replication initiation 1.627968e-2
GO:0006119 oxidative phosphorylation 1.635895e-2
GO:0090279 regulation of calcium ion import 1.665163e-2
GO:0046718 entry of virus into host cell 1.685009e-2
GO:0043628 ncRNA 3'-end processing 1.689688e-2
GO:0006172 ADP biosynthetic process 1.689688e-2
GO:0045906 negative regulation of vasoconstriction 1.709738e-2
GO:0050779 RNA destabilization 1.709738e-2
GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling 1.720585e-2
GO:0030968 endoplasmic reticulum unfolded protein response 1.722181e-2
GO:0048752 semicircular canal morphogenesis 1.722855e-2
GO:0051898 negative regulation of protein kinase B signaling cascade 1.757910e-2
GO:0010874 regulation of cholesterol efflux 1.757910e-2
GO:0031167 rRNA methylation 1.762439e-2
GO:0035967 cellular response to topologically incorrect protein 1.775087e-2
GO:0021569 rhombomere 3 development 1.781772e-2
GO:0001768 establishment of T cell polarity 1.784550e-2
GO:0016090 prenol metabolic process 1.788121e-2
GO:0033490 cholesterol biosynthetic process via lathosterol 1.789084e-2
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 1.789084e-2
GO:0071279 cellular response to cobalt ion 1.789084e-2
GO:0042376 phylloquinone catabolic process 1.789084e-2
GO:0010637 negative regulation of mitochondrial fusion 1.789084e-2
GO:0017126 nucleologenesis 1.789084e-2
GO:0030150 protein import into mitochondrial matrix 1.789084e-2
GO:0033085 negative regulation of T cell differentiation in thymus 1.807913e-2
GO:0021678 third ventricle development 1.828487e-2
GO:0021795 cerebral cortex cell migration 1.852566e-2
GO:0070947 neutrophil mediated killing of fungus 1.853217e-2
GO:0051030 snRNA transport 1.853217e-2
GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 1.853217e-2
GO:0006189 'de novo' IMP biosynthetic process 1.853217e-2
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway 1.853217e-2
GO:0032108 negative regulation of response to nutrient levels 1.854053e-2
GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 1.864082e-2
GO:0045342 MHC class II biosynthetic process 1.883861e-2
GO:0043091 L-arginine import 1.883861e-2
GO:0070839 divalent metal ion export 1.883861e-2
GO:0006876 cellular cadmium ion homeostasis 1.883861e-2
GO:0015707 nitrite transport 1.883861e-2
GO:0032632 interleukin-3 production 1.883861e-2
GO:0007098 centrosome cycle 1.884336e-2
GO:0001878 response to yeast 1.913769e-2
GO:0003310 pancreatic A cell differentiation 1.919349e-2
GO:0015684 ferrous iron transport 1.920194e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0046477 glycosylceramide catabolic process 1.695751e-14
GO:0019673 GDP-mannose metabolic process 1.138116e-10
GO:0035269 protein O-linked mannosylation 1.278721e-10
GO:0046479 glycosphingolipid catabolic process 1.407510e-10
GO:0019348 dolichol metabolic process 5.192265e-10
GO:0043653 mitochondrial fragmentation involved in apoptosis 5.192265e-10
GO:0006677 glycosylceramide metabolic process 7.357993e-10
GO:0030240 skeletal muscle thin filament assembly 2.013869e-9
GO:0090083 regulation of inclusion body assembly 2.856457e-9
GO:0019377 glycolipid catabolic process 1.159828e-8
GO:0006396 RNA processing 1.239272e-8
GO:0044248 cellular catabolic process 1.592039e-8
GO:0006680 glucosylceramide catabolic process 1.633663e-8
GO:0018192 enzyme active site formation via L-cysteine persulfide 1.971821e-8
GO:0043503 skeletal muscle fiber adaptation 1.742659e-7
GO:0006013 mannose metabolic process 4.909894e-7
GO:0034641 cellular nitrogen compound metabolic process 5.588003e-7
GO:0006139 nucleobase-containing compound metabolic process 5.762381e-7
GO:0014866 skeletal myofibril assembly 5.950279e-7
GO:0002098 tRNA wobble uridine modification 8.599318e-7
GO:0016139 glycoside catabolic process 8.611878e-7
GO:0006493 protein O-linked glycosylation 1.030879e-6
GO:0061084 negative regulation of protein refolding 1.530904e-6
GO:0034227 tRNA thio-modification 1.695758e-6
GO:0016236 macroautophagy 3.780690e-6
GO:0006678 glucosylceramide metabolic process 3.828022e-6
GO:0016574 histone ubiquitination 4.283964e-6
GO:0016071 mRNA metabolic process 4.415892e-6
GO:0034660 ncRNA metabolic process 5.004308e-6
GO:0009056 catabolic process 5.361525e-6
GO:0035645 enteric smooth muscle cell differentiation 6.043014e-6
GO:0007497 posterior midgut development 6.043014e-6
GO:0000956 nuclear-transcribed mRNA catabolic process 6.280156e-6
GO:0032481 positive regulation of type I interferon production 6.590457e-6
GO:0009057 macromolecule catabolic process 7.803699e-6
GO:0032515 negative regulation of phosphoprotein phosphatase activity 9.832258e-6
GO:0015780 nucleotide-sugar transport 1.092907e-5
GO:0034655 nucleobase-containing compound catabolic process 1.203682e-5
GO:0008334 histone mRNA metabolic process 1.240983e-5
GO:0044270 cellular nitrogen compound catabolic process 1.304020e-5
GO:0015992 proton transport 1.326396e-5
GO:0033238 regulation of cellular amine metabolic process 1.566457e-5
GO:0021528 commissural neuron differentiation in spinal cord 1.765020e-5
GO:0006807 nitrogen compound metabolic process 1.773761e-5
GO:0046700 heterocycle catabolic process 1.864660e-5
GO:0003096 renal sodium ion transport 1.956480e-5
GO:0032782 bile acid secretion 1.956480e-5
GO:0051351 positive regulation of ligase activity 1.964096e-5
GO:0006818 hydrogen transport 2.006608e-5
GO:0045345 positive regulation of MHC class I biosynthetic process 2.011406e-5
GO:0009154 purine ribonucleotide catabolic process 2.045853e-5
GO:0006657 CDP-choline pathway 2.132558e-5
GO:0006195 purine nucleotide catabolic process 2.201368e-5
GO:0009144 purine nucleoside triphosphate metabolic process 2.201835e-5
GO:0006402 mRNA catabolic process 2.242483e-5
GO:0007051 spindle organization 2.286821e-5
GO:0072523 purine-containing compound catabolic process 2.429632e-5
GO:0009205 purine ribonucleoside triphosphate metabolic process 2.514878e-5
GO:0009141 nucleoside triphosphate metabolic process 2.550359e-5
GO:0034470 ncRNA processing 2.591815e-5
GO:0009166 nucleotide catabolic process 2.625697e-5
GO:0009259 ribonucleotide metabolic process 2.966292e-5
GO:0009199 ribonucleoside triphosphate metabolic process 2.966314e-5
GO:0009207 purine ribonucleoside triphosphate catabolic process 3.059803e-5
GO:0070534 protein K63-linked ubiquitination 3.154447e-5
GO:0010467 gene expression 3.499042e-5
GO:0009261 ribonucleotide catabolic process 3.597064e-5
GO:0021570 rhombomere 4 development 3.710982e-5
GO:0009143 nucleoside triphosphate catabolic process 3.720745e-5
GO:0070925 organelle assembly 3.987079e-5
GO:0006401 RNA catabolic process 4.050719e-5
GO:0032416 negative regulation of sodium:hydrogen antiporter activity 4.769388e-5
GO:0000045 autophagic vacuole assembly 5.180620e-5
GO:0009146 purine nucleoside triphosphate catabolic process 5.430065e-5
GO:0009150 purine ribonucleotide metabolic process 5.504216e-5
GO:0022613 ribonucleoprotein complex biogenesis 5.665536e-5
GO:0045343 regulation of MHC class I biosynthetic process 6.415774e-5
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 6.540512e-5
GO:0032513 negative regulation of protein phosphatase type 2B activity 6.791871e-5
GO:0016226 iron-sulfur cluster assembly 6.939358e-5
GO:0071843 cellular component biogenesis at cellular level 7.514462e-5
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 7.822543e-5
GO:0006625 protein targeting to peroxisome 8.274844e-5
GO:0032727 positive regulation of interferon-alpha production 8.810037e-5
GO:0006200 ATP catabolic process 8.906663e-5
GO:0051645 Golgi localization 9.210374e-5
GO:0060047 heart contraction 9.782122e-5
GO:0048484 enteric nervous system development 9.892487e-5
GO:0032479 regulation of type I interferon production 1.024457e-4
GO:0006163 purine nucleotide metabolic process 1.028834e-4
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway 1.064661e-4
GO:2000781 positive regulation of double-strand break repair 1.064661e-4
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.093973e-4
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.093973e-4
GO:0072643 interferon-gamma secretion 1.093973e-4
GO:0090198 negative regulation of chemokine secretion 1.093973e-4
GO:0072608 interleukin-10 secretion 1.093973e-4
GO:0070963 positive regulation of neutrophil mediated killing of gram-negative bacterium 1.093973e-4
GO:0032707 negative regulation of interleukin-23 production 1.093973e-4
GO:0050983 deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase 1.093973e-4
GO:0035926 chemokine (C-C motif) ligand 2 secretion 1.093973e-4
GO:0045362 positive regulation of interleukin-1 biosynthetic process 1.093973e-4
GO:0043311 positive regulation of eosinophil degranulation 1.093973e-4
GO:0090304 nucleic acid metabolic process 1.172489e-4
GO:0043316 cytotoxic T cell degranulation 1.226962e-4
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway 1.226962e-4
GO:0033522 histone H2A ubiquitination 1.259149e-4
GO:0030433 ER-associated protein catabolic process 1.453206e-4
GO:0007340 acrosome reaction 1.549454e-4
GO:0042743 hydrogen peroxide metabolic process 1.596647e-4
GO:0051488 activation of anaphase-promoting complex activity 1.619161e-4
GO:0046688 response to copper ion 1.627234e-4
GO:0060005 vestibular reflex 1.656983e-4
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 1.669674e-4
GO:0016072 rRNA metabolic process 1.776184e-4
GO:0060048 cardiac muscle contraction 1.958020e-4
GO:0090169 regulation of spindle assembly 2.019832e-4
GO:0090234 regulation of kinetochore assembly 2.019832e-4
GO:0043491 protein kinase B signaling cascade 2.062783e-4
GO:0085020 protein K6-linked ubiquitination 2.072011e-4
GO:0016567 protein ubiquitination 2.157674e-4
GO:0097029 mature dendritic cell differentiation 2.167470e-4
GO:0040040 thermosensory behavior 2.167470e-4
GO:0051775 response to redox state 2.167470e-4
GO:0009220 pyrimidine ribonucleotide biosynthetic process 2.223017e-4
GO:0061099 negative regulation of protein tyrosine kinase activity 2.307391e-4
GO:0090084 negative regulation of inclusion body assembly 2.592649e-4
GO:0090086 negative regulation of protein deubiquitination 2.675020e-4
GO:0010845 positive regulation of reciprocal meiotic recombination 2.736626e-4
GO:0033239 negative regulation of cellular amine metabolic process 2.874481e-4
GO:2000272 negative regulation of receptor activity 2.884826e-4
GO:0042384 cilium assembly 2.982301e-4
GO:0030149 sphingolipid catabolic process 3.021807e-4
GO:0046514 ceramide catabolic process 3.085306e-4
GO:0015991 ATP hydrolysis coupled proton transport 3.218808e-4
GO:0006664 glycolipid metabolic process 3.408963e-4
GO:0006397 mRNA processing 3.628114e-4
GO:0006914 autophagy 3.664562e-4
GO:0000379 tRNA-type intron splice site recognition and cleavage 3.671698e-4
GO:2000649 regulation of sodium ion transmembrane transporter activity 3.677389e-4
GO:0044265 cellular macromolecule catabolic process 3.677448e-4
GO:0007214 gamma-aminobutyric acid signaling pathway 3.683033e-4
GO:0006646 phosphatidylethanolamine biosynthetic process 3.828709e-4
GO:0045792 negative regulation of cell size 3.893389e-4
GO:0010390 histone monoubiquitination 4.286680e-4
GO:0032446 protein modification by small protein conjugation 4.343102e-4
GO:0008637 apoptotic mitochondrial changes 4.515810e-4
GO:0018243 protein O-linked glycosylation via threonine 4.576571e-4
GO:0018242 protein O-linked glycosylation via serine 4.576571e-4
GO:0045787 positive regulation of cell cycle 4.721487e-4
GO:0048246 macrophage chemotaxis 4.779925e-4
GO:0009620 response to fungus 4.810769e-4
GO:0043403 skeletal muscle tissue regeneration 5.011660e-4
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 5.165622e-4
GO:0016070 RNA metabolic process 5.396146e-4
GO:0006220 pyrimidine nucleotide metabolic process 5.400135e-4
GO:0000147 actin cortical patch assembly 5.479878e-4
GO:0046034 ATP metabolic process 5.599528e-4
GO:2000688 positive regulation of rubidium ion transmembrane transporter activity 5.681330e-4
GO:2000682 positive regulation of rubidium ion transport 5.681330e-4
GO:0001682 tRNA 5'-leader removal 5.681330e-4
GO:0016078 tRNA catabolic process 5.681330e-4
GO:0035826 rubidium ion transport 5.681330e-4
GO:0008654 phospholipid biosynthetic process 5.950020e-4
GO:0060658 nipple morphogenesis 6.120852e-4
GO:0072521 purine-containing compound metabolic process 6.165394e-4
GO:0009218 pyrimidine ribonucleotide metabolic process 6.325160e-4
GO:0016090 prenol metabolic process 6.378260e-4
GO:0055072 iron ion homeostasis 6.666498e-4
GO:0051321 meiotic cell cycle 6.726122e-4
GO:0080164 regulation of nitric oxide metabolic process 6.780228e-4
GO:0006683 galactosylceramide catabolic process 6.780228e-4
GO:0003015 heart process 6.933237e-4
GO:0016558 protein import into peroxisome matrix 6.972353e-4
GO:0051443 positive regulation of ubiquitin-protein ligase activity 7.056857e-4
GO:0006412 translation 7.073553e-4
GO:0046364 monosaccharide biosynthetic process 7.144574e-4
GO:0006513 protein monoubiquitination 7.600051e-4
GO:0006213 pyrimidine nucleoside metabolic process 7.621156e-4
GO:0006364 rRNA processing 7.887970e-4
GO:0050746 regulation of lipoprotein metabolic process 7.973880e-4
GO:0010927 cellular component assembly involved in morphogenesis 8.021564e-4
GO:0043949 regulation of cAMP-mediated signaling 8.402495e-4
GO:0045764 positive regulation of cellular amino acid metabolic process 8.519462e-4
GO:0051340 regulation of ligase activity 8.664272e-4
GO:0046548 retinal rod cell development 8.843434e-4
GO:0000079 regulation of cyclin-dependent protein kinase activity 8.869110e-4
GO:0043555 regulation of translation in response to stress 9.171774e-4
GO:0070562 regulation of vitamin D receptor signaling pathway 9.343082e-4
GO:0051661 maintenance of centrosome location 9.502175e-4
GO:0033240 positive regulation of cellular amine metabolic process 9.744184e-4
GO:0008380 RNA splicing 9.945963e-4
GO:0009996 negative regulation of cell fate specification 1.035100e-3
GO:0009117 nucleotide metabolic process 1.044117e-3
GO:0044260 cellular macromolecule metabolic process 1.056880e-3
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 1.058441e-3
GO:0022417 protein maturation by protein folding 1.058441e-3
GO:0018158 protein oxidation 1.058441e-3
GO:0010454 negative regulation of cell fate commitment 1.066061e-3
GO:0046131 pyrimidine ribonucleoside metabolic process 1.069334e-3
GO:0071044 histone mRNA catabolic process 1.118594e-3
GO:0015696 ammonium transport 1.118594e-3
GO:0060674 placenta blood vessel development 1.131913e-3
GO:0051549 positive regulation of keratinocyte migration 1.139185e-3
GO:0032728 positive regulation of interferon-beta production 1.155637e-3
GO:0045083 negative regulation of interleukin-12 biosynthetic process 1.173196e-3
GO:0001881 receptor recycling 1.173196e-3
GO:0055089 fatty acid homeostasis 1.182438e-3
GO:0000305 response to oxygen radical 1.259169e-3
GO:0006457 protein folding 1.362916e-3
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 1.372017e-3
GO:0043484 regulation of RNA splicing 1.374503e-3
GO:0043558 regulation of translational initiation in response to stress 1.384713e-3
GO:0022403 cell cycle phase 1.497306e-3
GO:0007494 midgut development 1.498013e-3
GO:0032347 regulation of aldosterone biosynthetic process 1.524346e-3
GO:0050691 regulation of defense response to virus by host 1.528835e-3
GO:0034661 ncRNA catabolic process 1.543691e-3
GO:0016137 glycoside metabolic process 1.602226e-3
GO:0031274 positive regulation of pseudopodium assembly 1.606715e-3
GO:0044237 cellular metabolic process 1.623274e-3
GO:0000375 RNA splicing, via transesterification reactions 1.623323e-3
GO:0034587 piRNA metabolic process 1.684257e-3
GO:0045358 negative regulation of interferon-beta biosynthetic process 1.722300e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 1.722300e-3
GO:0030328 prenylcysteine catabolic process 1.722300e-3
GO:0070627 ferrous iron import 1.731698e-3
GO:0015676 vanadium ion transport 1.731698e-3
GO:0015692 lead ion transport 1.731698e-3
GO:0019319 hexose biosynthetic process 1.787112e-3
GO:0000279 M phase 1.806966e-3
GO:0034442 regulation of lipoprotein oxidation 1.832476e-3
GO:0033119 negative regulation of RNA splicing 1.853272e-3
GO:0050748 negative regulation of lipoprotein metabolic process 1.869515e-3
GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1.911404e-3
GO:0002339 B cell selection 1.987091e-3
GO:0006398 histone mRNA 3'-end processing 1.998552e-3
GO:0006172 ADP biosynthetic process 1.998552e-3
GO:0055086 nucleobase-containing small molecule metabolic process 2.005796e-3
GO:0002825 regulation of T-helper 1 type immune response 2.017999e-3
GO:0060668 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling 2.050423e-3
GO:0000398 nuclear mRNA splicing, via spliceosome 2.063904e-3
GO:0019430 removal of superoxide radicals 2.075805e-3
GO:0000413 protein peptidyl-prolyl isomerization 2.076553e-3
GO:0045922 negative regulation of fatty acid metabolic process 2.077591e-3
GO:0032647 regulation of interferon-alpha production 2.121789e-3
GO:0001732 formation of translation initiation complex 2.125123e-3
GO:0046007 negative regulation of activated T cell proliferation 2.176139e-3
GO:0006259 DNA metabolic process 2.179478e-3
GO:0072527 pyrimidine-containing compound metabolic process 2.216606e-3
GO:0006222 UMP biosynthetic process 2.252097e-3
GO:0032349 positive regulation of aldosterone biosynthetic process 2.255022e-3
GO:0051004 regulation of lipoprotein lipase activity 2.362007e-3
GO:0000188 inactivation of MAPK activity 2.373100e-3
GO:0090305 nucleic acid phosphodiester bond hydrolysis 2.408503e-3
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 2.440815e-3
GO:0060534 trachea cartilage development 2.440815e-3
GO:0043526 neuroprotection 2.515038e-3
GO:0001756 somitogenesis 2.610581e-3
GO:0021569 rhombomere 3 development 2.613094e-3
GO:0051289 protein homotetramerization 2.774481e-3
GO:0006405 RNA export from nucleus 2.779396e-3
GO:0070914 UV-damage excision repair 2.810521e-3
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 2.810521e-3
GO:0045414 regulation of interleukin-8 biosynthetic process 2.869672e-3
GO:0060017 parathyroid gland development 2.869672e-3
GO:0033120 positive regulation of RNA splicing 2.904013e-3
GO:0035426 extracellular matrix-cell signaling 2.906108e-3
GO:0030033 microvillus assembly 2.908602e-3
GO:0046466 membrane lipid catabolic process 2.945483e-3
GO:0070535 histone H2A K63-linked ubiquitination 2.952525e-3
GO:0016142 O-glycoside catabolic process 2.952525e-3
GO:0042443 phenylethylamine metabolic process 2.952525e-3
GO:0031272 regulation of pseudopodium assembly 2.978535e-3
GO:0035082 axoneme assembly 2.979010e-3
GO:0006004 fucose metabolic process 2.979010e-3
GO:0046434 organophosphate catabolic process 3.173893e-3
GO:0051225 spindle assembly 3.173990e-3
GO:0060716 labyrinthine layer blood vessel development 3.181471e-3
GO:0030163 protein catabolic process 3.194982e-3
GO:0009133 nucleoside diphosphate biosynthetic process 3.218562e-3
GO:0035307 positive regulation of protein dephosphorylation 3.277377e-3
GO:0014826 vein smooth muscle contraction 3.306745e-3
GO:0034224 cellular response to zinc ion starvation 3.385573e-3
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 3.385573e-3
GO:0006043 glucosamine catabolic process 3.400044e-3
GO:0042069 regulation of catecholamine metabolic process 3.437265e-3
GO:0006221 pyrimidine nucleotide biosynthetic process 3.678082e-3
GO:0002230 positive regulation of defense response to virus by host 3.691388e-3
GO:0042304 regulation of fatty acid biosynthetic process 3.712601e-3
GO:0031669 cellular response to nutrient levels 3.726035e-3
GO:0035306 positive regulation of dephosphorylation 3.772726e-3
GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 3.812190e-3
GO:0006473 protein acetylation 3.824895e-3
GO:0016075 rRNA catabolic process 3.830062e-3
GO:0090085 regulation of protein deubiquitination 3.882911e-3
GO:2000043 regulation of cardiac cell fate specification 3.904201e-3
GO:0015986 ATP synthesis coupled proton transport 3.937813e-3
GO:0008634 negative regulation of survival gene product expression 3.941488e-3
GO:0002827 positive regulation of T-helper 1 type immune response 3.941488e-3
GO:0044090 positive regulation of vacuole organization 3.980851e-3
GO:0009234 menaquinone biosynthetic process 3.980851e-3
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 4.003882e-3
GO:0007140 male meiosis 4.124691e-3
GO:0033962 cytoplasmic mRNA processing body assembly 4.145165e-3
GO:0035852 horizontal cell localization 4.202061e-3
GO:0035849 nephric duct elongation 4.202061e-3
GO:0043048 dolichyl monophosphate biosynthetic process 4.202061e-3
GO:0071279 cellular response to cobalt ion 4.202061e-3
GO:0035847 uterine epithelium development 4.202061e-3
GO:0070370 cellular heat acclimation 4.202061e-3
GO:2000768 positive regulation of nephron tubule epithelial cell differentiation 4.202061e-3
GO:0035846 oviduct epithelium development 4.202061e-3
GO:0006348 chromatin silencing at telomere 4.202061e-3
GO:0010637 negative regulation of mitochondrial fusion 4.202061e-3
GO:0009794 regulation of mitotic cell cycle, embryonic 4.202061e-3
GO:0032802 low-density lipoprotein particle receptor catabolic process 4.202061e-3
GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 4.202061e-3
GO:0030261 chromosome condensation 4.220308e-3
GO:0010155 regulation of proton transport 4.241471e-3
GO:0050832 defense response to fungus 4.329933e-3
GO:0046939 nucleotide phosphorylation 4.329933e-3
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 4.338261e-3
GO:0071034 CUT catabolic process 4.348639e-3
GO:0051382 kinetochore assembly 4.348639e-3
GO:0018298 protein-chromophore linkage 4.353238e-3
GO:0008033 tRNA processing 4.413922e-3
GO:0032677 regulation of interleukin-8 production 4.430309e-3
GO:0070936 protein K48-linked ubiquitination 4.432977e-3
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 4.444394e-3
GO:0006749 glutathione metabolic process 4.580987e-3
GO:0060631 regulation of meiosis I 4.726705e-3
GO:0045357 regulation of interferon-beta biosynthetic process 4.726705e-3
GO:0032007 negative regulation of TOR signaling cascade 4.799979e-3
GO:0042660 positive regulation of cell fate specification 4.917218e-3
GO:0006413 translational initiation 4.961855e-3
GO:2000036 regulation of stem cell maintenance 5.101950e-3
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 5.110710e-3
GO:0046165 alcohol biosynthetic process 5.152681e-3
GO:0034637 cellular carbohydrate biosynthetic process 5.152681e-3
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent 5.159823e-3
GO:0002175 protein localization to paranode region of axon 5.159823e-3
GO:0051572 negative regulation of histone H3-K4 methylation 5.189660e-3
GO:0060586 multicellular organismal iron ion homeostasis 5.248395e-3
GO:0042254 ribosome biogenesis 5.474145e-3
GO:0050668 positive regulation of homocysteine metabolic process 5.492972e-3
GO:0045963 negative regulation of dopamine metabolic process 5.492972e-3
GO:0034635 glutathione transport 5.492972e-3
GO:0016073 snRNA metabolic process 5.552807e-3
GO:0006264 mitochondrial DNA replication 5.569350e-3
GO:0001826 inner cell mass cell differentiation 5.569350e-3
GO:0034755 iron ion transmembrane transport 5.589224e-3
GO:0061136 regulation of proteasomal protein catabolic process 5.686325e-3
GO:0030307 positive regulation of cell growth 5.718551e-3
GO:0007126 meiosis 5.834697e-3
GO:0042053 regulation of dopamine metabolic process 5.919986e-3
GO:0072528 pyrimidine-containing compound biosynthetic process 6.106035e-3
GO:0071545 inositol phosphate catabolic process 6.214918e-3
GO:0000303 response to superoxide 6.233011e-3
GO:0001836 release of cytochrome c from mitochondria 6.302315e-3
GO:0006687 glycosphingolipid metabolic process 6.333840e-3
GO:0048255 mRNA stabilization 6.373176e-3
GO:0010950 positive regulation of endopeptidase activity 6.375814e-3
GO:0045217 cell-cell junction maintenance 6.382647e-3
GO:0033128 negative regulation of histone phosphorylation 6.459498e-3
GO:0010501 RNA secondary structure unwinding 6.459498e-3
GO:0021530 spinal cord oligodendrocyte cell fate specification 6.459498e-3
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 6.466234e-3
GO:0006475 internal protein amino acid acetylation 6.691164e-3
GO:0046587 positive regulation of calcium-dependent cell-cell adhesion 6.733206e-3
GO:0051895 negative regulation of focal adhesion assembly 6.913102e-3
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity 6.935791e-3
GO:0090310 negative regulation of methylation-dependent chromatin silencing 6.935791e-3
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 6.935791e-3
GO:0045046 protein import into peroxisome membrane 6.935791e-3
GO:0032094 response to food 6.939089e-3
GO:0007141 male meiosis I 6.944664e-3
GO:0043320 natural killer cell degranulation 6.966196e-3
GO:0018126 protein hydroxylation 7.066782e-3
GO:0007033 vacuole organization 7.308838e-3
GO:0045906 negative regulation of vasoconstriction 7.495963e-3
GO:0014043 negative regulation of neuron maturation 7.495963e-3
GO:0048384 retinoic acid receptor signaling pathway 7.689408e-3
GO:0045872 positive regulation of rhodopsin gene expression 7.721308e-3
GO:2000653 regulation of genetic imprinting 7.721308e-3
GO:0034276 kynurenic acid biosynthetic process 7.721308e-3
GO:0002534 cytokine production involved in inflammatory response 7.721308e-3
GO:0032298 positive regulation of DNA-dependent DNA replication initiation 7.721308e-3
GO:0002159 desmosome assembly 7.721308e-3
GO:0070885 negative regulation of calcineurin-NFAT signaling pathway 7.769143e-3
GO:0042264 peptidyl-aspartic acid hydroxylation 7.769143e-3
GO:0001892 embryonic placenta development 7.985949e-3
GO:0007031 peroxisome organization 8.054054e-3
GO:0048752 semicircular canal morphogenesis 8.057713e-3
GO:0006885 regulation of pH 8.188558e-3
GO:0006406 mRNA export from nucleus 8.383642e-3
GO:0042744 hydrogen peroxide catabolic process 8.414755e-3
GO:0051030 snRNA transport 8.418408e-3
GO:0042351 'de novo' GDP-L-fucose biosynthetic process 8.418408e-3
GO:0000492 box C/D snoRNP assembly 8.418408e-3
GO:0019509 L-methionine salvage from methylthioadenosine 8.418408e-3
GO:0009260 ribonucleotide biosynthetic process 8.447119e-3
GO:0035434 copper ion transmembrane transport 8.492344e-3
GO:0060535 trachea cartilage morphogenesis 8.492344e-3
GO:0046173 polyol biosynthetic process 8.504143e-3
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 8.620491e-3
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 8.620491e-3
GO:0007176 regulation of epidermal growth factor-activated receptor activity 8.744570e-3
GO:0006612 protein targeting to membrane 8.942318e-3
GO:0071108 protein K48-linked deubiquitination 9.141777e-3
GO:0042350 GDP-L-fucose biosynthetic process 9.262483e-3
GO:0010900 negative regulation of phosphatidylcholine catabolic process 9.295490e-3
GO:0045416 positive regulation of interleukin-8 biosynthetic process 9.295490e-3
GO:0046039 GTP metabolic process 9.377886e-3
GO:0071267 L-methionine salvage 9.531592e-3
GO:0008156 negative regulation of DNA replication 9.718461e-3
GO:0019217 regulation of fatty acid metabolic process 1.030759e-2
GO:0018393 internal peptidyl-lysine acetylation 1.033947e-2
GO:0060319 primitive erythrocyte differentiation 1.037228e-2
GO:0046322 negative regulation of fatty acid oxidation 1.037228e-2
GO:0006879 cellular iron ion homeostasis 1.053358e-2
GO:0060709 glycogen cell development involved in embryonic placenta development 1.081251e-2
GO:0045626 negative regulation of T-helper 1 cell differentiation 1.081251e-2
GO:0034135 regulation of toll-like receptor 2 signaling pathway 1.081251e-2
GO:0002537 nitric oxide production involved in inflammatory response 1.081251e-2
GO:0035282 segmentation 1.083987e-2
GO:0006228 UTP biosynthetic process 1.084074e-2
GO:0006165 nucleoside diphosphate phosphorylation 1.084074e-2
GO:0046483 heterocycle metabolic process 1.085122e-2
GO:0060711 labyrinthine layer development 1.086547e-2
GO:0051438 regulation of ubiquitin-protein ligase activity 1.088698e-2
GO:0010520 regulation of reciprocal meiotic recombination 1.091990e-2
GO:0021612 facial nerve structural organization 1.091990e-2
GO:0001755 neural crest cell migration 1.113008e-2
GO:0032107 regulation of response to nutrient levels 1.123631e-2
GO:0006415 translational termination 1.141784e-2
GO:0008635 activation of caspase activity by cytochrome c 1.168043e-2
GO:0030277 maintenance of gastrointestinal epithelium 1.168726e-2
GO:0009132 nucleoside diphosphate metabolic process 1.172071e-2
GO:0010741 negative regulation of intracellular protein kinase cascade 1.182274e-2
GO:0009267 cellular response to starvation 1.189377e-2
GO:0006399 tRNA metabolic process 1.197195e-2
GO:0018394 peptidyl-lysine acetylation 1.226480e-2
GO:0071985 multivesicular body sorting pathway 1.234393e-2
GO:0046985 positive regulation of hemoglobin biosynthetic process 1.234393e-2
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 1.234393e-2
GO:0043973 histone H3-K4 acetylation 1.234393e-2
GO:0060729 intestinal epithelial structure maintenance 1.234680e-2
GO:0060482 lobar bronchus development 1.252191e-2
GO:0045618 positive regulation of keratinocyte differentiation 1.252191e-2
GO:0070634 transepithelial ammonium transport 1.254835e-2
GO:0061113 pancreas morphogenesis 1.254835e-2
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 1.275557e-2
GO:0014041 regulation of neuron maturation 1.278104e-2
GO:0046031 ADP metabolic process 1.278104e-2
GO:0060166 olfactory pit development 1.279711e-2
GO:0035444 nickel ion transmembrane transport 1.279711e-2
GO:0031999 negative regulation of fatty acid beta-oxidation 1.279711e-2
GO:0071956 cellular component maintenance at cellular level 1.283383e-2
GO:0030970 retrograde protein transport, ER to cytosol 1.287904e-2
GO:0001913 T cell mediated cytotoxicity 1.287904e-2
GO:0032006 regulation of TOR signaling cascade 1.290124e-2
GO:0010269 response to selenium ion 1.302629e-2
GO:0006352 transcription initiation, DNA-dependent 1.318956e-2
GO:0070979 protein K11-linked ubiquitination 1.322442e-2
GO:0032413 negative regulation of ion transmembrane transporter activity 1.323742e-2
GO:0044085 cellular component biogenesis 1.344053e-2
GO:0043309 regulation of eosinophil degranulation 1.348786e-2
GO:0097152 mesenchymal cell apoptosis 1.348786e-2
GO:0042137 sequestering of neurotransmitter 1.348786e-2
GO:0034633 retinol transport 1.348786e-2
GO:0009597 detection of virus 1.348786e-2
GO:0035674 tricarboxylic acid transmembrane transport 1.348786e-2
GO:0009145 purine nucleoside triphosphate biosynthetic process 1.365152e-2
GO:0023021 termination of signal transduction 1.366424e-2
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 1.366424e-2
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 1.366424e-2
GO:0051647 nucleus localization 1.382344e-2
GO:0008629 induction of apoptosis by intracellular signals 1.405822e-2
GO:0016180 snRNA processing 1.416871e-2
GO:0045604 regulation of epidermal cell differentiation 1.444529e-2
GO:0042119 neutrophil activation 1.445468e-2
GO:0006516 glycoprotein catabolic process 1.448231e-2
GO:0030031 cell projection assembly 1.464150e-2
GO:0046683 response to organophosphorus 1.477418e-2
GO:0061015 snRNA import into nucleus 1.477418e-2
GO:0045769 negative regulation of asymmetric cell division 1.477418e-2
GO:0035502 metanephric ureteric bud development 1.477418e-2
GO:0061316 canonical Wnt receptor signaling pathway involved in heart development 1.480908e-2
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 1.480908e-2
GO:0006436 tryptophanyl-tRNA aminoacylation 1.480908e-2
GO:0045047 protein targeting to ER 1.492056e-2
GO:0050665 hydrogen peroxide biosynthetic process 1.498467e-2
GO:0006183 GTP biosynthetic process 1.498467e-2
GO:0043407 negative regulation of MAP kinase activity 1.505626e-2
GO:0010887 negative regulation of cholesterol storage 1.506393e-2
GO:0042424 catecholamine catabolic process 1.535490e-2
GO:0002344 B cell affinity maturation 1.535490e-2
GO:0006828 manganese ion transport 1.552647e-2
GO:0022618 ribonucleoprotein complex assembly 1.565524e-2