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Novel motif:43

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name:motif43_CCCWGT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0006955 immune response 1.652121e-30
GO:0006952 defense response 4.095253e-28
GO:0006954 inflammatory response 3.896688e-20
GO:0071732 cellular response to nitric oxide 4.021675e-19
GO:0002376 immune system process 5.637123e-18
GO:0045087 innate immune response 5.364561e-16
GO:0071731 response to nitric oxide 1.095755e-13
GO:0007509 mesoderm migration involved in gastrulation 1.725644e-13
GO:0034340 response to type I interferon 2.088184e-13
GO:0060337 type I interferon-mediated signaling pathway 2.147029e-13
GO:0008078 mesodermal cell migration 1.278854e-12
GO:0002682 regulation of immune system process 1.491119e-12
GO:0009612 response to mechanical stimulus 1.653626e-12
GO:0009605 response to external stimulus 6.552023e-12
GO:0010033 response to organic substance 8.628763e-12
GO:0070849 response to epidermal growth factor stimulus 9.490442e-12
GO:0007586 digestion 1.081475e-11
GO:0035814 negative regulation of renal sodium excretion 1.485814e-11
GO:0010985 negative regulation of lipoprotein particle clearance 4.271018e-11
GO:0001817 regulation of cytokine production 4.983770e-11
GO:0050896 response to stimulus 7.045515e-11
GO:0042424 catecholamine catabolic process 9.454898e-11
GO:0010941 regulation of cell death 1.071641e-10
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.417967e-10
GO:0019221 cytokine-mediated signaling pathway 2.433345e-10
GO:0002443 leukocyte mediated immunity 2.524107e-10
GO:0030185 nitric oxide transport 2.783750e-10
GO:0022617 extracellular matrix disassembly 3.750144e-10
GO:0010243 response to organic nitrogen 4.868484e-10
GO:0030010 establishment of cell polarity 5.250875e-10
GO:0001101 response to acid 7.114715e-10
GO:0031960 response to corticosteroid stimulus 1.056492e-9
GO:0051707 response to other organism 1.296504e-9
GO:0060290 transdifferentiation 1.328773e-9
GO:0002684 positive regulation of immune system process 1.392838e-9
GO:0032203 telomere formation via telomerase 1.549575e-9
GO:0009607 response to biotic stimulus 2.130538e-9
GO:0043200 response to amino acid stimulus 2.155669e-9
GO:0033986 response to methanol 2.211935e-9
GO:0046687 response to chromate 2.211935e-9
GO:0048545 response to steroid hormone stimulus 2.354199e-9
GO:0000302 response to reactive oxygen species 2.618237e-9
GO:0045026 plasma membrane fusion 2.674615e-9
GO:0048584 positive regulation of response to stimulus 2.752980e-9
GO:0042981 regulation of apoptosis 3.502706e-9
GO:0043067 regulation of programmed cell death 3.538055e-9
GO:0071417 cellular response to organic nitrogen 4.115900e-9
GO:0034014 response to triglyceride 4.543619e-9
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 5.945344e-9
GO:0007585 respiratory gaseous exchange 9.212380e-9
GO:0065008 regulation of biological quality 9.548626e-9
GO:0009253 peptidoglycan catabolic process 1.024466e-8
GO:0009611 response to wounding 1.137546e-8
GO:0044281 small molecule metabolic process 1.180278e-8
GO:0008610 lipid biosynthetic process 1.243957e-8
GO:0071418 cellular response to amine stimulus 1.319913e-8
GO:0007154 cell communication 1.378893e-8
GO:0009628 response to abiotic stimulus 1.532083e-8
GO:0019882 antigen processing and presentation 1.546051e-8
GO:0001819 positive regulation of cytokine production 1.583968e-8
GO:0023052 signaling 1.756279e-8
GO:0045834 positive regulation of lipid metabolic process 1.940467e-8
GO:0042420 dopamine catabolic process 2.217878e-8
GO:0071260 cellular response to mechanical stimulus 2.342687e-8
GO:0009719 response to endogenous stimulus 2.429291e-8
GO:0010872 regulation of cholesterol esterification 2.473828e-8
GO:0016064 immunoglobulin mediated immune response 2.526981e-8
GO:0070417 cellular response to cold 2.709066e-8
GO:0002449 lymphocyte mediated immunity 3.313638e-8
GO:0042592 homeostatic process 3.973593e-8
GO:0071230 cellular response to amino acid stimulus 4.105974e-8
GO:0034097 response to cytokine stimulus 4.304087e-8
GO:0046902 regulation of mitochondrial membrane permeability 4.590053e-8
GO:0050776 regulation of immune response 4.753600e-8
GO:0044255 cellular lipid metabolic process 5.261144e-8
GO:0006342 chromatin silencing 5.527642e-8
GO:0007568 aging 5.566104e-8
GO:0006629 lipid metabolic process 5.802416e-8
GO:0016052 carbohydrate catabolic process 6.015702e-8
GO:0002237 response to molecule of bacterial origin 6.558806e-8
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.851869e-8
GO:0014075 response to amine stimulus 7.281177e-8
GO:0044283 small molecule biosynthetic process 7.441396e-8
GO:0009966 regulation of signal transduction 7.941366e-8
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 7.962685e-8
GO:0032916 positive regulation of transforming growth factor beta3 production 8.821362e-8
GO:0019724 B cell mediated immunity 8.916804e-8
GO:0042221 response to chemical stimulus 9.706334e-8
GO:0048583 regulation of response to stimulus 9.919739e-8
GO:0006022 aminoglycan metabolic process 1.009513e-7
GO:0002149 hypochlorous acid biosynthetic process 1.085852e-7
GO:0010536 positive regulation of activation of Janus kinase activity 1.088525e-7
GO:0042542 response to hydrogen peroxide 1.233364e-7
GO:0032496 response to lipopolysaccharide 1.233427e-7
GO:0071229 cellular response to acid 1.265087e-7
GO:0006909 phagocytosis 1.345459e-7
GO:0045471 response to ethanol 1.359773e-7
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1.378605e-7
GO:0007342 fusion of sperm to egg plasma membrane 1.384678e-7
GO:0045940 positive regulation of steroid metabolic process 1.517341e-7
GO:0048519 negative regulation of biological process 1.557539e-7
GO:0090130 tissue migration 1.560016e-7
GO:0021984 adenohypophysis development 1.815782e-7
GO:0010873 positive regulation of cholesterol esterification 1.850478e-7
GO:0044062 regulation of excretion 1.856744e-7
GO:0007165 signal transduction 1.886331e-7
GO:0002252 immune effector process 1.922591e-7
GO:0051384 response to glucocorticoid stimulus 2.181515e-7
GO:0051704 multi-organism process 2.253935e-7
GO:0023051 regulation of signaling 2.318176e-7
GO:0035813 regulation of renal sodium excretion 2.345266e-7
GO:0007166 cell surface receptor linked signaling pathway 2.397883e-7
GO:0045814 negative regulation of gene expression, epigenetic 2.647845e-7
GO:0009895 negative regulation of catabolic process 2.750406e-7
GO:0033189 response to vitamin A 2.974651e-7
GO:0006631 fatty acid metabolic process 3.285192e-7
GO:0060333 interferon-gamma-mediated signaling pathway 3.361947e-7
GO:0009967 positive regulation of signal transduction 3.426060e-7
GO:0006953 acute-phase response 3.701151e-7
GO:0044236 multicellular organismal metabolic process 4.423180e-7
GO:0090218 positive regulation of lipid kinase activity 4.557392e-7
GO:0010741 negative regulation of intracellular protein kinase cascade 4.851528e-7
GO:0015671 oxygen transport 5.275926e-7
GO:0002253 activation of immune response 5.297234e-7
GO:0031667 response to nutrient levels 5.462092e-7
GO:0045730 respiratory burst 5.579041e-7
GO:0032910 regulation of transforming growth factor beta3 production 5.840366e-7
GO:0010900 negative regulation of phosphatidylcholine catabolic process 6.267023e-7
GO:0032012 regulation of ARF protein signal transduction 6.303864e-7
GO:0008284 positive regulation of cell proliferation 6.388992e-7
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity 6.442028e-7
GO:0009991 response to extracellular stimulus 6.445842e-7
GO:0002526 acute inflammatory response 6.668088e-7
GO:0051937 catecholamine transport 6.710474e-7
GO:0002250 adaptive immune response 6.922626e-7
GO:0046164 alcohol catabolic process 7.237629e-7
GO:0002579 positive regulation of antigen processing and presentation 7.664862e-7
GO:0048878 chemical homeostasis 7.922084e-7
GO:0032202 telomere assembly 8.153405e-7
GO:0019321 pentose metabolic process 8.729189e-7
GO:0043086 negative regulation of catalytic activity 8.924141e-7
GO:0000413 protein peptidyl-prolyl isomerization 1.011173e-6
GO:0060548 negative regulation of cell death 1.076514e-6
GO:0060326 cell chemotaxis 1.077413e-6
GO:0010989 negative regulation of low-density lipoprotein particle clearance 1.125697e-6
GO:0015844 monoamine transport 1.257819e-6
GO:0050830 defense response to Gram-positive bacterium 1.324297e-6
GO:0043066 negative regulation of apoptosis 1.454586e-6
GO:0051591 response to cAMP 1.455213e-6
GO:0050778 positive regulation of immune response 1.520338e-6
GO:0033273 response to vitamin 1.631864e-6
GO:0018208 peptidyl-proline modification 1.666935e-6
GO:0001880 Mullerian duct regression 1.728783e-6
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 1.750948e-6
GO:0046949 fatty-acyl-CoA biosynthetic process 1.773796e-6
GO:0048518 positive regulation of biological process 1.806493e-6
GO:0051291 protein heterooligomerization 1.811911e-6
GO:0032787 monocarboxylic acid metabolic process 2.097913e-6
GO:0046394 carboxylic acid biosynthetic process 2.254793e-6
GO:0010987 negative regulation of high-density lipoprotein particle clearance 2.326754e-6
GO:0010897 negative regulation of triglyceride catabolic process 2.326754e-6
GO:0002251 organ or tissue specific immune response 2.396644e-6
GO:0060696 regulation of phospholipid catabolic process 2.437890e-6
GO:0046314 phosphocreatine biosynthetic process 2.459085e-6
GO:0015669 gas transport 2.500515e-6
GO:0021858 GABAergic neuron differentiation in basal ganglia 2.682427e-6
GO:0051005 negative regulation of lipoprotein lipase activity 2.682427e-6
GO:0032094 response to food 2.787378e-6
GO:0007163 establishment or maintenance of cell polarity 2.873643e-6
GO:0042992 negative regulation of transcription factor import into nucleus 2.935325e-6
GO:0071345 cellular response to cytokine stimulus 2.968650e-6
GO:0007006 mitochondrial membrane organization 3.070076e-6
GO:0042396 phosphagen biosynthetic process 3.190794e-6
GO:0042994 cytoplasmic sequestering of transcription factor 3.457573e-6
GO:0048247 lymphocyte chemotaxis 3.507533e-6
GO:0034505 tooth mineralization 3.571496e-6
GO:0045338 farnesyl diphosphate metabolic process 3.635070e-6
GO:0010875 positive regulation of cholesterol efflux 3.670155e-6
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 3.719076e-6
GO:0032663 regulation of interleukin-2 production 3.800281e-6
GO:0016458 gene silencing 3.909074e-6
GO:0010646 regulation of cell communication 3.979804e-6
GO:0051001 negative regulation of nitric-oxide synthase activity 4.017826e-6
GO:0000920 cytokinetic cell separation 4.023909e-6
GO:0051179 localization 4.221191e-6
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 4.377345e-6
GO:0006950 response to stress 4.401587e-6
GO:0043069 negative regulation of programmed cell death 4.402288e-6
GO:0048352 paraxial mesoderm structural organization 4.779123e-6
GO:0021998 neural plate mediolateral regionalization 4.779123e-6
GO:0042347 negative regulation of NF-kappaB import into nucleus 4.789581e-6
GO:0072132 mesenchyme morphogenesis 4.832931e-6
GO:0031330 negative regulation of cellular catabolic process 4.915752e-6
GO:0006026 aminoglycan catabolic process 5.111862e-6
GO:0008217 regulation of blood pressure 5.326454e-6
GO:0007296 vitellogenesis 5.370399e-6
GO:0019048 virus-host interaction 5.469477e-6
GO:0019049 evasion of host defenses by virus 5.647848e-6
GO:0010988 regulation of low-density lipoprotein particle clearance 5.702601e-6
GO:0007183 SMAD protein complex assembly 5.715289e-6
GO:0044258 intestinal lipid catabolic process 5.757193e-6
GO:0018350 protein esterification 5.757193e-6
GO:0009725 response to hormone stimulus 5.802229e-6
GO:0051220 cytoplasmic sequestering of protein 5.918852e-6
GO:0044341 sodium-dependent phosphate transport 6.043521e-6
GO:0032088 negative regulation of NF-kappaB transcription factor activity 6.178290e-6
GO:0048535 lymph node development 6.329797e-6
GO:0045806 negative regulation of endocytosis 6.735740e-6
GO:0044092 negative regulation of molecular function 6.754142e-6
GO:0034201 response to oleic acid 6.953020e-6
GO:0048255 mRNA stabilization 7.586309e-6
GO:0043550 regulation of lipid kinase activity 7.656723e-6
GO:0043300 regulation of leukocyte degranulation 7.826255e-6
GO:0009617 response to bacterium 8.003408e-6
GO:0070887 cellular response to chemical stimulus 8.171981e-6
GO:0042177 negative regulation of protein catabolic process 8.255342e-6
GO:0007179 transforming growth factor beta receptor signaling pathway 8.639942e-6
GO:0048002 antigen processing and presentation of peptide antigen 8.671565e-6
GO:0006007 glucose catabolic process 8.919209e-6
GO:0030203 glycosaminoglycan metabolic process 9.562559e-6
GO:0010718 positive regulation of epithelial to mesenchymal transition 1.095948e-5
GO:0034341 response to interferon-gamma 1.128572e-5
GO:0050764 regulation of phagocytosis 1.137319e-5
GO:0060644 mammary gland epithelial cell differentiation 1.138260e-5
GO:0016044 cellular membrane organization 1.157618e-5
GO:0050865 regulation of cell activation 1.181366e-5
GO:0014070 response to organic cyclic compound 1.190742e-5
GO:0061180 mammary gland epithelium development 1.253580e-5
GO:0051051 negative regulation of transport 1.262983e-5
GO:0051239 regulation of multicellular organismal process 1.277584e-5
GO:0006916 anti-apoptosis 1.363224e-5
GO:0050832 defense response to fungus 1.369263e-5
GO:0061024 membrane organization 1.371450e-5
GO:0044130 negative regulation of growth of symbiont in host 1.440628e-5
GO:0046514 ceramide catabolic process 1.470577e-5
GO:0007109 cytokinesis, completion of separation 1.484489e-5
GO:0002694 regulation of leukocyte activation 1.489274e-5
GO:0060351 cartilage development involved in endochondral bone morphogenesis 1.527109e-5
GO:0002679 respiratory burst involved in defense response 1.547188e-5
GO:0044259 multicellular organismal macromolecule metabolic process 1.685259e-5
GO:0051251 positive regulation of lymphocyte activation 1.725134e-5
GO:0071705 nitrogen compound transport 1.777953e-5
GO:0002098 tRNA wobble uridine modification 1.807152e-5
GO:0034227 tRNA thio-modification 1.807152e-5
GO:0051246 regulation of protein metabolic process 1.852091e-5
GO:0006014 D-ribose metabolic process 1.885730e-5
GO:0006810 transport 2.003996e-5
GO:0044275 cellular carbohydrate catabolic process 2.077662e-5
GO:0010984 regulation of lipoprotein particle clearance 2.142860e-5
GO:0007259 JAK-STAT cascade 2.214696e-5
GO:0010627 regulation of intracellular protein kinase cascade 2.221355e-5
GO:0048261 negative regulation of receptor-mediated endocytosis 2.272082e-5
GO:0002886 regulation of myeloid leukocyte mediated immunity 2.286713e-5
GO:0019432 triglyceride biosynthetic process 2.345215e-5
GO:0043304 regulation of mast cell degranulation 2.433927e-5
GO:0071299 cellular response to vitamin A 2.486495e-5
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 2.526252e-5
GO:0051249 regulation of lymphocyte activation 2.530670e-5
GO:0002764 immune response-regulating signaling pathway 2.545553e-5
GO:0006633 fatty acid biosynthetic process 2.785801e-5
GO:0007000 nucleolus organization 2.786374e-5
GO:0051234 establishment of localization 2.792335e-5
GO:0051716 cellular response to stimulus 2.863955e-5
GO:0008366 axon ensheathment 2.869295e-5
GO:0050801 ion homeostasis 2.912887e-5
GO:0042552 myelination 3.087930e-5
GO:0050848 regulation of calcium-mediated signaling 3.088364e-5
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 3.147790e-5
GO:0016126 sterol biosynthetic process 3.174429e-5
GO:0003218 cardiac left ventricle formation 3.185392e-5
GO:0042127 regulation of cell proliferation 3.239183e-5
GO:0030595 leukocyte chemotaxis 3.243420e-5
GO:0007181 transforming growth factor beta receptor complex assembly 3.253105e-5
GO:0006082 organic acid metabolic process 3.266166e-5
GO:0033211 adiponectin-mediated signaling pathway 3.274089e-5
GO:0003334 keratinocyte development 3.546165e-5
GO:0032963 collagen metabolic process 3.574963e-5
GO:0070542 response to fatty acid 3.579374e-5
GO:0019320 hexose catabolic process 3.589485e-5
GO:0050829 defense response to Gram-negative bacterium 3.608058e-5
GO:0006690 icosanoid metabolic process 3.621636e-5
GO:0032964 collagen biosynthetic process 3.649405e-5
GO:0090138 regulation of actin cytoskeleton organization by cell-cell adhesion 3.709597e-5
GO:0055080 cation homeostasis 3.832381e-5
GO:0022009 central nervous system vasculogenesis 3.846092e-5
GO:0071346 cellular response to interferon-gamma 3.911767e-5
GO:0033239 negative regulation of cellular amine metabolic process 4.101710e-5
GO:0002478 antigen processing and presentation of exogenous peptide antigen 4.111558e-5
GO:0002218 activation of innate immune response 4.176824e-5
GO:0006544 glycine metabolic process 4.233203e-5
GO:0032879 regulation of localization 4.391366e-5
GO:0071300 cellular response to retinoic acid 4.430595e-5
GO:0015937 coenzyme A biosynthetic process 4.474868e-5
GO:0030913 paranodal junction assembly 4.540937e-5
GO:0060346 bone trabecula formation 4.557413e-5
GO:0043249 erythrocyte maturation 4.609843e-5
GO:0033559 unsaturated fatty acid metabolic process 4.674271e-5
GO:0060764 cell-cell signaling involved in mammary gland development 4.729695e-5
GO:0042503 tyrosine phosphorylation of Stat3 protein 5.006637e-5
GO:0042398 cellular modified amino acid biosynthetic process 5.069568e-5
GO:0009308 amine metabolic process 5.086486e-5
GO:0001973 adenosine receptor signaling pathway 5.122472e-5
GO:0033993 response to lipid 5.298226e-5
GO:0031347 regulation of defense response 5.333270e-5
GO:0007253 cytoplasmic sequestering of NF-kappaB 5.360647e-5
GO:0010888 negative regulation of lipid storage 5.368927e-5
GO:0010647 positive regulation of cell communication 5.448616e-5
GO:0046320 regulation of fatty acid oxidation 5.548234e-5
GO:0006637 acyl-CoA metabolic process 5.568198e-5
GO:0002828 regulation of type 2 immune response 5.609456e-5
GO:0009583 detection of light stimulus 5.634541e-5
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 5.693077e-5
GO:0071391 cellular response to estrogen stimulus 5.904605e-5
GO:0071214 cellular response to abiotic stimulus 5.988964e-5
GO:0046365 monosaccharide catabolic process 6.114916e-5
GO:0042133 neurotransmitter metabolic process 6.119011e-5
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process 6.387728e-5
GO:0046502 uroporphyrinogen III metabolic process 6.452219e-5
GO:0046128 purine ribonucleoside metabolic process 6.468256e-5
GO:0019216 regulation of lipid metabolic process 6.656035e-5
GO:0046007 negative regulation of activated T cell proliferation 6.701762e-5
GO:0002523 leukocyte migration involved in inflammatory response 6.701762e-5
GO:0046822 regulation of nucleocytoplasmic transport 6.844480e-5
GO:0008063 Toll signaling pathway 6.855966e-5
GO:0035556 intracellular signal transduction 6.886191e-5
GO:0006692 prostanoid metabolic process 6.935521e-5
GO:0032526 response to retinoic acid 6.990359e-5
GO:0050900 leukocyte migration 7.033032e-5
GO:0019884 antigen processing and presentation of exogenous antigen 7.056392e-5
GO:0002921 negative regulation of humoral immune response 7.158484e-5
GO:0009414 response to water deprivation 7.194135e-5
GO:0015872 dopamine transport 7.293736e-5
GO:0032456 endocytic recycling 7.310016e-5
GO:0032506 cytokinetic process 7.356134e-5
GO:0015840 urea transport 7.356134e-5
GO:0007584 response to nutrient 7.359255e-5
GO:0002432 granuloma formation 7.435962e-5
GO:0061383 trabecula morphogenesis 7.437759e-5
GO:0022415 viral reproductive process 7.448263e-5
GO:0032376 positive regulation of cholesterol transport 7.464553e-5
GO:0030334 regulation of cell migration 7.529867e-5
GO:0009416 response to light stimulus 7.629519e-5
GO:0023056 positive regulation of signaling 7.677213e-5
GO:0042942 D-serine transport 7.999909e-5
GO:0030953 astral microtubule organization 8.025650e-5
GO:0030198 extracellular matrix organization 8.383076e-5
GO:0044241 lipid digestion 8.447860e-5
GO:0042278 purine nucleoside metabolic process 8.639382e-5
GO:0010740 positive regulation of intracellular protein kinase cascade 8.667486e-5
GO:0048710 regulation of astrocyte differentiation 8.701949e-5
GO:0060708 spongiotrophoblast differentiation 8.849894e-5
GO:0042108 positive regulation of cytokine biosynthetic process 9.201612e-5
GO:0006032 chitin catabolic process 9.209446e-5
GO:0001300 chronological cell aging 9.244550e-5
GO:0007263 nitric oxide mediated signal transduction 9.314380e-5
GO:0003084 positive regulation of systemic arterial blood pressure 9.379841e-5
GO:0000132 establishment of mitotic spindle orientation 9.411050e-5
GO:0060749 mammary gland alveolus development 9.421941e-5
GO:0018193 peptidyl-amino acid modification 9.491506e-5
GO:0065007 biological regulation 9.653199e-5
GO:0055085 transmembrane transport 9.669214e-5
GO:0050863 regulation of T cell activation 9.675177e-5
GO:0050867 positive regulation of cell activation 9.913526e-5
GO:0010824 regulation of centrosome duplication 1.010269e-4
GO:0060973 cell migration involved in heart development 1.036462e-4
GO:0009306 protein secretion 1.046425e-4
GO:0045088 regulation of innate immune response 1.048431e-4
GO:0006695 cholesterol biosynthetic process 1.061933e-4
GO:0016139 glycoside catabolic process 1.080042e-4
GO:0045651 positive regulation of macrophage differentiation 1.127633e-4
GO:0016137 glycoside metabolic process 1.177171e-4
GO:0002696 positive regulation of leukocyte activation 1.189015e-4
GO:0006662 glycerol ether metabolic process 1.197755e-4
GO:0070208 protein heterotrimerization 1.215083e-4
GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 1.215324e-4
GO:0001957 intramembranous ossification 1.239946e-4
GO:0071383 cellular response to steroid hormone stimulus 1.241952e-4
GO:0048241 epinephrine transport 1.254929e-4
GO:0006400 tRNA modification 1.261093e-4
GO:0014829 vascular smooth muscle contraction 1.261254e-4
GO:0072593 reactive oxygen species metabolic process 1.263061e-4
GO:0006720 isoprenoid metabolic process 1.266542e-4
GO:0015879 carnitine transport 1.276744e-4
GO:2000145 regulation of cell motility 1.276855e-4
GO:0042440 pigment metabolic process 1.287658e-4
GO:0032312 regulation of ARF GTPase activity 1.291971e-4
GO:0032703 negative regulation of interleukin-2 production 1.301156e-4
GO:0042506 tyrosine phosphorylation of Stat5 protein 1.321258e-4
GO:0031133 regulation of axon diameter 1.332503e-4
GO:0060480 lung goblet cell differentiation 1.344951e-4
GO:0044240 multicellular organismal lipid catabolic process 1.361133e-4
GO:0032880 regulation of protein localization 1.365655e-4
GO:0002513 tolerance induction to self antigen 1.417941e-4
GO:0046434 organophosphate catabolic process 1.455441e-4
GO:0000090 mitotic anaphase 1.455441e-4
GO:0060482 lobar bronchus development 1.461502e-4
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1.477548e-4
GO:0046483 heterocycle metabolic process 1.493719e-4
GO:0046730 induction of host immune response by virus 1.499326e-4
GO:0046456 icosanoid biosynthetic process 1.514173e-4
GO:0034763 negative regulation of transmembrane transport 1.526616e-4
GO:0046498 S-adenosylhomocysteine metabolic process 1.541011e-4
GO:0043407 negative regulation of MAP kinase activity 1.556631e-4
GO:0042744 hydrogen peroxide catabolic process 1.565299e-4
GO:0042454 ribonucleoside catabolic process 1.627090e-4
GO:0032288 myelin assembly 1.650870e-4
GO:0032740 positive regulation of interleukin-17 production 1.654934e-4
GO:0048523 negative regulation of cellular process 1.675146e-4
GO:0009749 response to glucose stimulus 1.679237e-4
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 1.688430e-4
GO:0046504 glycerol ether biosynthetic process 1.704397e-4
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1.718269e-4
GO:0035411 catenin import into nucleus 1.725079e-4
GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway 1.764646e-4
GO:0019752 carboxylic acid metabolic process 1.781015e-4
GO:0050747 positive regulation of lipoprotein metabolic process 1.792469e-4
GO:0042493 response to drug 1.853296e-4
GO:0008065 establishment of blood-nerve barrier 1.867633e-4
GO:0051241 negative regulation of multicellular organismal process 1.873017e-4
GO:0010745 negative regulation of macrophage derived foam cell differentiation 1.888479e-4
GO:0060620 regulation of cholesterol import 1.920634e-4
GO:0009259 ribonucleotide metabolic process 1.943799e-4
GO:0000089 mitotic metaphase 1.944685e-4
GO:0009150 purine ribonucleotide metabolic process 1.976124e-4
GO:0006740 NADPH regeneration 1.986081e-4
GO:0006636 unsaturated fatty acid biosynthetic process 1.990593e-4
GO:0060659 nipple sheath formation 2.062749e-4
GO:0060649 mammary gland bud elongation 2.062749e-4
GO:0060444 branching involved in mammary gland duct morphogenesis 2.086847e-4
GO:0006766 vitamin metabolic process 2.113609e-4
GO:0060712 spongiotrophoblast layer development 2.122754e-4
GO:0048477 oogenesis 2.129522e-4
GO:0034142 toll-like receptor 4 signaling pathway 2.134356e-4
GO:0043301 negative regulation of leukocyte degranulation 2.134407e-4
GO:0006959 humoral immune response 2.199690e-4
GO:0014910 regulation of smooth muscle cell migration 2.239282e-4
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 2.251383e-4
GO:0014874 response to stimulus involved in regulation of muscle adaptation 2.264192e-4
GO:0060262 negative regulation of N-terminal protein palmitoylation 2.272410e-4
GO:0060343 trabecula formation 2.286054e-4
GO:0009119 ribonucleoside metabolic process 2.290662e-4
GO:0070201 regulation of establishment of protein localization 2.304762e-4
GO:0060341 regulation of cellular localization 2.319392e-4
GO:0043206 fibril organization 2.324826e-4
GO:0060980 cell migration involved in coronary vasculogenesis 2.412641e-4
GO:0051973 positive regulation of telomerase activity 2.435765e-4
GO:0016090 prenol metabolic process 2.435765e-4
GO:2000147 positive regulation of cell motility 2.481681e-4
GO:0009309 amine biosynthetic process 2.490622e-4
GO:0043471 regulation of cellular carbohydrate catabolic process 2.492108e-4
GO:0002920 regulation of humoral immune response 2.541322e-4
GO:0071310 cellular response to organic substance 2.543121e-4
GO:0050790 regulation of catalytic activity 2.566460e-4
GO:0046626 regulation of insulin receptor signaling pathway 2.574366e-4
GO:0040007 growth 2.601861e-4
GO:0045351 type I interferon biosynthetic process 2.615792e-4
GO:0072521 purine-containing compound metabolic process 2.643053e-4
GO:0071294 cellular response to zinc ion 2.649328e-4
GO:0042512 negative regulation of tyrosine phosphorylation of Stat1 protein 2.658936e-4
GO:0034767 positive regulation of ion transmembrane transport 2.658936e-4
GO:0006098 pentose-phosphate shunt 2.689430e-4
GO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation 2.697173e-4
GO:0060621 negative regulation of cholesterol import 2.714283e-4
GO:0048771 tissue remodeling 2.720660e-4
GO:0046165 alcohol biosynthetic process 2.722755e-4
GO:0009620 response to fungus 2.728061e-4
GO:0042180 cellular ketone metabolic process 2.739746e-4
GO:0042136 neurotransmitter biosynthetic process 2.751787e-4
GO:0051347 positive regulation of transferase activity 2.775167e-4
GO:0009145 purine nucleoside triphosphate biosynthetic process 2.777146e-4
GO:0072376 protein activation cascade 2.829907e-4
GO:0045084 positive regulation of interleukin-12 biosynthetic process 2.855873e-4
GO:0051972 regulation of telomerase activity 2.863623e-4
GO:0009142 nucleoside triphosphate biosynthetic process 2.863919e-4
GO:0044243 multicellular organismal catabolic process 2.864224e-4
GO:0034134 toll-like receptor 2 signaling pathway 2.865879e-4
GO:0034130 toll-like receptor 1 signaling pathway 2.865879e-4
GO:0009201 ribonucleoside triphosphate biosynthetic process 2.923157e-4
GO:0048522 positive regulation of cellular process 2.975880e-4
GO:0046364 monosaccharide biosynthetic process 2.979944e-4
GO:0006754 ATP biosynthetic process 3.027021e-4
GO:0043901 negative regulation of multi-organism process 3.070836e-4
GO:0032845 negative regulation of homeostatic process 3.118456e-4
GO:0009301 snRNA transcription 3.149015e-4
GO:0006739 NADP metabolic process 3.161057e-4
GO:0060576 intestinal epithelial cell development 3.166321e-4
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 3.183747e-4
GO:0045777 positive regulation of blood pressure 3.196273e-4
GO:0032495 response to muramyl dipeptide 3.198215e-4
GO:0001661 conditioned taste aversion 3.202996e-4
GO:0006110 regulation of glycolysis 3.296436e-4
GO:0006812 cation transport 3.297637e-4
GO:0050663 cytokine secretion 3.313454e-4
GO:0032536 regulation of cell projection size 3.346072e-4
GO:0055072 iron ion homeostasis 3.360684e-4
GO:0048382 mesendoderm development 3.363537e-4
GO:0007602 phototransduction 3.448139e-4
GO:0035419 activation of MAPK activity involved in innate immune response 3.454013e-4
GO:0010951 negative regulation of endopeptidase activity 3.458777e-4
GO:0003417 growth plate cartilage development 3.474499e-4


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0002739 regulation of cytokine secretion involved in immune response 1.625587e-10
GO:0002478 antigen processing and presentation of exogenous peptide antigen 4.393675e-10
GO:0060621 negative regulation of cholesterol import 6.036169e-10
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 8.271525e-10
GO:0009214 cyclic nucleotide catabolic process 1.142667e-9
GO:0010033 response to organic substance 1.971380e-9
GO:0060620 regulation of cholesterol import 2.332433e-9
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 2.564271e-9
GO:0019884 antigen processing and presentation of exogenous antigen 3.556924e-9
GO:0060907 positive regulation of macrophage cytokine production 4.740162e-9
GO:0032103 positive regulation of response to external stimulus 7.324866e-9
GO:0009125 nucleoside monophosphate catabolic process 7.377837e-9
GO:0002687 positive regulation of leukocyte migration 8.606994e-9
GO:0002718 regulation of cytokine production involved in immune response 1.166280e-8
GO:0006518 peptide metabolic process 1.283861e-8
GO:0043647 inositol phosphate metabolic process 1.382541e-8
GO:0002443 leukocyte mediated immunity 1.403430e-8
GO:0006360 transcription from RNA polymerase I promoter 2.316744e-8
GO:0001961 positive regulation of cytokine-mediated signaling pathway 3.264733e-8
GO:0002688 regulation of leukocyte chemotaxis 4.125408e-8
GO:0034763 negative regulation of transmembrane transport 4.208794e-8
GO:0002690 positive regulation of leukocyte chemotaxis 4.674189e-8
GO:0034762 regulation of transmembrane transport 4.744437e-8
GO:0010987 negative regulation of high-density lipoprotein particle clearance 5.334767e-8
GO:0010897 negative regulation of triglyceride catabolic process 5.334767e-8
GO:0035691 macrophage migration inhibitory factor signaling pathway 6.295849e-8
GO:0051234 establishment of localization 7.303139e-8
GO:0002685 regulation of leukocyte migration 7.641393e-8
GO:0050713 negative regulation of interleukin-1 beta secretion 9.520810e-8
GO:0009895 negative regulation of catabolic process 9.861467e-8
GO:0046339 diacylglycerol metabolic process 1.212990e-7
GO:0002577 regulation of antigen processing and presentation 1.228545e-7
GO:0070536 protein K63-linked deubiquitination 1.248733e-7
GO:0051241 negative regulation of multicellular organismal process 1.330112e-7
GO:0002449 lymphocyte mediated immunity 1.332315e-7
GO:0002720 positive regulation of cytokine production involved in immune response 1.396460e-7
GO:0042221 response to chemical stimulus 1.698467e-7
GO:0002579 positive regulation of antigen processing and presentation 2.166327e-7
GO:0006198 cAMP catabolic process 2.251592e-7
GO:0010957 negative regulation of vitamin D biosynthetic process 2.260390e-7
GO:0048002 antigen processing and presentation of peptide antigen 2.346093e-7
GO:0090209 negative regulation of triglyceride metabolic process 3.456999e-7
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 4.497534e-7
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 5.054511e-7
GO:0019882 antigen processing and presentation 5.330951e-7
GO:0055085 transmembrane transport 5.543818e-7
GO:0046058 cAMP metabolic process 5.759758e-7
GO:0002740 negative regulation of cytokine secretion involved in immune response 6.629338e-7
GO:0035094 response to nicotine 6.755747e-7
GO:0006116 NADH oxidation 7.055339e-7
GO:0001818 negative regulation of cytokine production 8.352542e-7
GO:0045933 positive regulation of muscle contraction 9.400359e-7
GO:0006810 transport 9.667158e-7
GO:0051085 chaperone mediated protein folding requiring cofactor 1.048727e-6
GO:0016064 immunoglobulin mediated immune response 1.181594e-6
GO:0045725 positive regulation of glycogen biosynthetic process 1.241214e-6
GO:0060760 positive regulation of response to cytokine stimulus 1.279564e-6
GO:0002252 immune effector process 1.321339e-6
GO:0006508 proteolysis 1.328823e-6
GO:0019724 B cell mediated immunity 1.640302e-6
GO:0050711 negative regulation of interleukin-1 secretion 1.827843e-6
GO:0050921 positive regulation of chemotaxis 1.839133e-6
GO:0050896 response to stimulus 2.094178e-6
GO:0010989 negative regulation of low-density lipoprotein particle clearance 2.392140e-6
GO:0042069 regulation of catecholamine metabolic process 2.681905e-6
GO:0009187 cyclic nucleotide metabolic process 2.874760e-6
GO:0032652 regulation of interleukin-1 production 2.922243e-6
GO:0090075 relaxation of muscle 3.119351e-6
GO:0015074 DNA integration 3.245886e-6
GO:0051223 regulation of protein transport 3.609279e-6
GO:0032369 negative regulation of lipid transport 3.645929e-6
GO:0032651 regulation of interleukin-1 beta production 3.678714e-6
GO:0045833 negative regulation of lipid metabolic process 3.779786e-6
GO:0007588 excretion 3.803217e-6
GO:0051049 regulation of transport 3.985464e-6
GO:0009719 response to endogenous stimulus 4.076902e-6
GO:0002821 positive regulation of adaptive immune response 4.147374e-6
GO:0032675 regulation of interleukin-6 production 4.485313e-6
GO:0042311 vasodilation 4.513231e-6
GO:0008211 glucocorticoid metabolic process 4.534427e-6
GO:0001817 regulation of cytokine production 4.599743e-6
GO:0007021 tubulin complex assembly 4.661142e-6
GO:0006749 glutathione metabolic process 4.729250e-6
GO:0070228 regulation of lymphocyte apoptosis 4.751860e-6
GO:0070307 lens fiber cell development 5.211839e-6
GO:0042420 dopamine catabolic process 5.261210e-6
GO:0032879 regulation of localization 5.609616e-6
GO:0007586 digestion 6.126824e-6
GO:0002604 regulation of dendritic cell antigen processing and presentation 6.183552e-6
GO:0070141 response to UV-A 6.865091e-6
GO:0003084 positive regulation of systemic arterial blood pressure 6.957290e-6
GO:0061024 membrane organization 7.082554e-6
GO:0010982 regulation of high-density lipoprotein particle clearance 7.937872e-6
GO:0070509 calcium ion import 8.549193e-6
GO:0019218 regulation of steroid metabolic process 8.754952e-6
GO:0014075 response to amine stimulus 8.779156e-6
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 9.122763e-6
GO:0006629 lipid metabolic process 9.378287e-6
GO:0051179 localization 9.927832e-6
GO:0031330 negative regulation of cellular catabolic process 1.004721e-5
GO:0002830 positive regulation of type 2 immune response 1.037526e-5
GO:0016044 cellular membrane organization 1.038623e-5
GO:0043242 negative regulation of protein complex disassembly 1.162390e-5
GO:0002702 positive regulation of production of molecular mediator of immune response 1.258524e-5
GO:0050848 regulation of calcium-mediated signaling 1.264903e-5
GO:0042053 regulation of dopamine metabolic process 1.427515e-5
GO:0031347 regulation of defense response 1.436150e-5
GO:0002034 regulation of blood vessel size by renin-angiotensin 1.460739e-5
GO:0014070 response to organic cyclic compound 1.484414e-5
GO:0001885 endothelial cell development 1.497839e-5
GO:0042424 catecholamine catabolic process 1.572720e-5
GO:0030834 regulation of actin filament depolymerization 1.594262e-5
GO:0032957 inositol trisphosphate metabolic process 1.634938e-5
GO:0010935 regulation of macrophage cytokine production 1.645284e-5
GO:0070201 regulation of establishment of protein localization 1.657159e-5
GO:0070508 cholesterol import 1.962107e-5
GO:0044062 regulation of excretion 2.204419e-5
GO:0002238 response to molecule of fungal origin 2.221771e-5
GO:0032386 regulation of intracellular transport 2.236586e-5
GO:0050729 positive regulation of inflammatory response 2.464768e-5
GO:0030835 negative regulation of actin filament depolymerization 2.485865e-5
GO:0010038 response to metal ion 2.544751e-5
GO:0006544 glycine metabolic process 2.558632e-5
GO:0044255 cellular lipid metabolic process 2.631991e-5
GO:0045987 positive regulation of smooth muscle contraction 2.654194e-5
GO:0048520 positive regulation of behavior 2.772541e-5
GO:0031349 positive regulation of defense response 2.895093e-5
GO:0045932 negative regulation of muscle contraction 3.106820e-5
GO:0032715 negative regulation of interleukin-6 production 3.107490e-5
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 3.135446e-5
GO:0071310 cellular response to organic substance 3.154891e-5
GO:0032101 regulation of response to external stimulus 3.414567e-5
GO:0046890 regulation of lipid biosynthetic process 3.814983e-5
GO:0048146 positive regulation of fibroblast proliferation 3.831844e-5
GO:0007015 actin filament organization 3.905147e-5
GO:2000107 negative regulation of leukocyte apoptosis 4.107410e-5
GO:0006952 defense response 4.215324e-5
GO:0009448 gamma-aminobutyric acid metabolic process 4.246953e-5
GO:2000484 positive regulation of interleukin-8 secretion 4.246953e-5
GO:0030334 regulation of cell migration 4.296223e-5
GO:0006651 diacylglycerol biosynthetic process 4.583930e-5
GO:0030574 collagen catabolic process 4.604229e-5
GO:0050707 regulation of cytokine secretion 4.673913e-5
GO:0051561 elevation of mitochondrial calcium ion concentration 4.702324e-5
GO:0002741 positive regulation of cytokine secretion involved in immune response 4.758595e-5
GO:0050995 negative regulation of lipid catabolic process 4.871770e-5
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 4.957454e-5
GO:0034380 high-density lipoprotein particle assembly 4.965373e-5
GO:0002902 regulation of B cell apoptosis 5.060412e-5
GO:0032963 collagen metabolic process 5.067229e-5
GO:0071418 cellular response to amine stimulus 5.165422e-5
GO:0016311 dephosphorylation 5.201896e-5
GO:0042558 pteridine-containing compound metabolic process 5.202799e-5
GO:0019637 organophosphate metabolic process 5.281616e-5
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5.289517e-5
GO:0060338 regulation of type I interferon-mediated signaling pathway 5.632151e-5
GO:0006955 immune response 5.748211e-5
GO:0009123 nucleoside monophosphate metabolic process 5.760956e-5
GO:0032602 chemokine production 5.798103e-5
GO:0000072 M phase specific microtubule process 5.816532e-5
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5.908739e-5
GO:0032375 negative regulation of cholesterol transport 6.098089e-5
GO:0046069 cGMP catabolic process 6.477491e-5
GO:0051693 actin filament capping 6.587803e-5
GO:0006575 cellular modified amino acid metabolic process 6.698876e-5
GO:0040017 positive regulation of locomotion 6.716936e-5
GO:0008637 apoptotic mitochondrial changes 7.129587e-5
GO:0010863 positive regulation of phospholipase C activity 7.341779e-5
GO:0033598 mammary gland epithelial cell proliferation 7.438555e-5
GO:0051084 'de novo' posttranslational protein folding 7.489175e-5
GO:2000145 regulation of cell motility 7.697217e-5
GO:0019216 regulation of lipid metabolic process 7.951865e-5
GO:0032642 regulation of chemokine production 8.122763e-5
GO:0090023 positive regulation of neutrophil chemotaxis 8.377760e-5
GO:0016090 prenol metabolic process 8.436080e-5
GO:0050706 regulation of interleukin-1 beta secretion 8.600110e-5
GO:0006958 complement activation, classical pathway 8.616874e-5
GO:2000273 positive regulation of receptor activity 8.664088e-5
GO:0046688 response to copper ion 8.678521e-5
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 8.868770e-5
GO:0070887 cellular response to chemical stimulus 8.960556e-5
GO:0071230 cellular response to amino acid stimulus 8.963525e-5
GO:0006897 endocytosis 9.172788e-5
GO:0043244 regulation of protein complex disassembly 9.567370e-5
GO:0043627 response to estrogen stimulus 9.655316e-5
GO:0006760 folic acid-containing compound metabolic process 9.657898e-5
GO:2000147 positive regulation of cell motility 9.838595e-5
GO:0050668 positive regulation of homocysteine metabolic process 1.002616e-4
GO:0045963 negative regulation of dopamine metabolic process 1.002616e-4
GO:0035419 activation of MAPK activity involved in innate immune response 1.002616e-4
GO:0015862 uridine transport 1.034434e-4
GO:0006883 cellular sodium ion homeostasis 1.034434e-4
GO:0002455 humoral immune response mediated by circulating immunoglobulin 1.066742e-4
GO:0071229 cellular response to acid 1.082801e-4
GO:0051403 stress-activated MAPK cascade 1.103240e-4
GO:0032880 regulation of protein localization 1.123671e-4
GO:0006957 complement activation, alternative pathway 1.146270e-4
GO:2000106 regulation of leukocyte apoptosis 1.150464e-4
GO:0032488 Cdc42 protein signal transduction 1.157568e-4
GO:0032691 negative regulation of interleukin-1 beta production 1.201447e-4
GO:0002237 response to molecule of bacterial origin 1.214146e-4
GO:0002684 positive regulation of immune system process 1.241962e-4
GO:0003073 regulation of systemic arterial blood pressure 1.255723e-4
GO:0061049 cell growth involved in cardiac muscle cell development 1.307288e-4
GO:0014873 response to muscle activity involved in regulation of muscle adaptation 1.307288e-4
GO:0003331 positive regulation of extracellular matrix constituent secretion 1.307288e-4
GO:0008065 establishment of blood-nerve barrier 1.307288e-4
GO:0070309 lens fiber cell morphogenesis 1.349177e-4
GO:0010035 response to inorganic substance 1.386668e-4
GO:0060067 cervix development 1.399839e-4
GO:0046697 decidualization 1.425769e-4
GO:0007202 activation of phospholipase C activity 1.444195e-4
GO:0090179 planar cell polarity pathway involved in neural tube closure 1.469935e-4
GO:0030335 positive regulation of cell migration 1.489541e-4
GO:0048149 behavioral response to ethanol 1.523117e-4
GO:0010193 response to ozone 1.573899e-4
GO:0060191 regulation of lipase activity 1.575362e-4
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 1.587550e-4
GO:0005979 regulation of glycogen biosynthetic process 1.623735e-4
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1.633741e-4
GO:0009310 amine catabolic process 1.664381e-4
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 1.672098e-4
GO:0050850 positive regulation of calcium-mediated signaling 1.704822e-4
GO:0045840 positive regulation of mitosis 1.747661e-4
GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis 1.755567e-4
GO:0050704 regulation of interleukin-1 secretion 1.756762e-4
GO:0042402 cellular biogenic amine catabolic process 1.756762e-4
GO:0001990 regulation of systemic arterial blood pressure by hormone 1.767567e-4
GO:0010518 positive regulation of phospholipase activity 1.789821e-4
GO:0032680 regulation of tumor necrosis factor production 1.832026e-4
GO:0051764 actin crosslink formation 1.844850e-4
GO:0090037 positive regulation of protein kinase C signaling cascade 1.844850e-4
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 1.844850e-4
GO:0071635 negative regulation of transforming growth factor beta production 1.846163e-4
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 1.854945e-4
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1.876795e-4
GO:0022900 electron transport chain 1.884705e-4
GO:0023052 signaling 1.911162e-4
GO:0042493 response to drug 1.930673e-4
GO:0001300 chronological cell aging 1.959362e-4
GO:0071417 cellular response to organic nitrogen 1.964701e-4
GO:0002250 adaptive immune response 1.991057e-4
GO:0010951 negative regulation of endopeptidase activity 2.003808e-4
GO:0060806 negative regulation of cell differentiation involved in embryonic placenta development 2.117508e-4
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 2.123131e-4
GO:0051270 regulation of cellular component movement 2.134318e-4
GO:0051657 maintenance of organelle location 2.161409e-4
GO:0090257 regulation of muscle system process 2.179182e-4
GO:0050795 regulation of behavior 2.192825e-4
GO:0070189 kynurenine metabolic process 2.194265e-4
GO:0010873 positive regulation of cholesterol esterification 2.194349e-4
GO:0051488 activation of anaphase-promoting complex activity 2.202018e-4
GO:0009607 response to biotic stimulus 2.250296e-4
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.266461e-4
GO:0050727 regulation of inflammatory response 2.283471e-4
GO:0070229 negative regulation of lymphocyte apoptosis 2.296477e-4
GO:0030837 negative regulation of actin filament polymerization 2.306030e-4
GO:0009617 response to bacterium 2.341221e-4
GO:0045651 positive regulation of macrophage differentiation 2.352599e-4
GO:0006477 protein sulfation 2.364701e-4
GO:0002019 regulation of renal output by angiotensin 2.382624e-4
GO:0032692 negative regulation of interleukin-1 production 2.390378e-4
GO:0070875 positive regulation of glycogen metabolic process 2.436614e-4
GO:0030300 regulation of intestinal cholesterol absorption 2.524548e-4
GO:0071545 inositol phosphate catabolic process 2.569318e-4
GO:0008207 C21-steroid hormone metabolic process 2.591238e-4
GO:0090022 regulation of neutrophil chemotaxis 2.603310e-4
GO:0070059 apoptosis in response to endoplasmic reticulum stress 2.628987e-4
GO:0043279 response to alkaloid 2.632871e-4
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 2.643468e-4
GO:0042177 negative regulation of protein catabolic process 2.648120e-4
GO:0045940 positive regulation of steroid metabolic process 2.683402e-4
GO:0032781 positive regulation of ATPase activity 2.699083e-4
GO:0019374 galactolipid metabolic process 2.710435e-4
GO:0048261 negative regulation of receptor-mediated endocytosis 2.756388e-4
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 2.794884e-4
GO:0071219 cellular response to molecule of bacterial origin 2.806623e-4
GO:0051272 positive regulation of cellular component movement 2.829797e-4
GO:0032677 regulation of interleukin-8 production 2.871896e-4
GO:0010872 regulation of cholesterol esterification 2.924997e-4
GO:0007154 cell communication 2.969669e-4
GO:0001812 positive regulation of type I hypersensitivity 3.003429e-4
GO:0050708 regulation of protein secretion 3.011722e-4
GO:0003218 cardiac left ventricle formation 3.034587e-4
GO:0007290 spermatid nucleus elongation 3.034587e-4
GO:0032649 regulation of interferon-gamma production 3.235993e-4
GO:0072668 tubulin complex biogenesis 3.254922e-4
GO:0071321 cellular response to cGMP 3.272812e-4
GO:0001101 response to acid 3.274197e-4
GO:0046855 inositol phosphate dephosphorylation 3.288479e-4
GO:0006950 response to stress 3.344462e-4
GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 3.368904e-4
GO:0051716 cellular response to stimulus 3.501395e-4
GO:0044259 multicellular organismal macromolecule metabolic process 3.505828e-4
GO:0045988 negative regulation of striated muscle contraction 3.515557e-4
GO:0052572 response to host immune response 3.536048e-4
GO:0034097 response to cytokine stimulus 3.540452e-4
GO:0032496 response to lipopolysaccharide 3.619024e-4
GO:0006664 glycolipid metabolic process 3.650100e-4
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 3.723611e-4
GO:0009166 nucleotide catabolic process 3.979682e-4
GO:0001759 organ induction 4.181258e-4
GO:0032227 negative regulation of synaptic transmission, dopaminergic 4.183740e-4
GO:0071495 cellular response to endogenous stimulus 4.258125e-4
GO:0070306 lens fiber cell differentiation 4.383695e-4
GO:0040012 regulation of locomotion 4.432016e-4
GO:0008616 queuosine biosynthetic process 4.451667e-4
GO:0032515 negative regulation of phosphoprotein phosphatase activity 4.556304e-4
GO:0046700 heterocycle catabolic process 4.563072e-4
GO:0007165 signal transduction 4.583134e-4
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 4.650010e-4
GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure 4.711188e-4
GO:0060341 regulation of cellular localization 4.744899e-4
GO:0046456 icosanoid biosynthetic process 4.790811e-4
GO:0044270 cellular nitrogen compound catabolic process 4.823993e-4
GO:0051646 mitochondrion localization 4.837474e-4
GO:0002339 B cell selection 4.908437e-4
GO:0051964 negative regulation of synapse assembly 4.908437e-4
GO:0031272 regulation of pseudopodium assembly 5.329460e-4
GO:0051055 negative regulation of lipid biosynthetic process 5.431280e-4
GO:0043086 negative regulation of catalytic activity 5.463916e-4
GO:0031915 positive regulation of synaptic plasticity 5.731044e-4
GO:0032930 positive regulation of superoxide anion generation 5.770351e-4
GO:0035150 regulation of tube size 5.803851e-4
GO:0006956 complement activation 5.877960e-4
GO:0042306 regulation of protein import into nucleus 5.884065e-4
GO:0050710 negative regulation of cytokine secretion 6.101750e-4
GO:0019058 viral infectious cycle 6.101750e-4
GO:0044058 regulation of digestive system process 6.110304e-4
GO:0006470 protein dephosphorylation 6.169432e-4
GO:0090076 relaxation of skeletal muscle 6.221990e-4
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 6.221990e-4
GO:0010948 negative regulation of cell cycle process 6.302981e-4
GO:0035556 intracellular signal transduction 6.307078e-4
GO:0051659 maintenance of mitochondrion location 6.308386e-4
GO:0051386 regulation of nerve growth factor receptor signaling pathway 6.346835e-4
GO:0048584 positive regulation of response to stimulus 6.392546e-4
GO:0008286 insulin receptor signaling pathway 6.517897e-4
GO:0010243 response to organic nitrogen 6.522093e-4
GO:0071216 cellular response to biotic stimulus 6.547275e-4
GO:0035813 regulation of renal sodium excretion 6.567800e-4
GO:0030162 regulation of proteolysis 6.578224e-4
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 6.601090e-4
GO:2000647 negative regulation of stem cell proliferation 6.645502e-4
GO:0070563 negative regulation of vitamin D receptor signaling pathway 6.645502e-4
GO:0035921 desmosome disassembly 6.645502e-4
GO:0010839 negative regulation of keratinocyte proliferation 6.645502e-4
GO:0061350 planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 6.652534e-4
GO:0061354 planar cell polarity pathway involved in pericardium morphogenesis 6.652534e-4
GO:0061349 planar cell polarity pathway involved in cardiac right atrium morphogenesis 6.652534e-4
GO:0061347 planar cell polarity pathway involved in outflow tract morphogenesis 6.652534e-4
GO:0060210 metestrus 6.652534e-4
GO:0061348 planar cell polarity pathway involved in ventricular septum morphogenesis 6.652534e-4
GO:0050880 regulation of blood vessel size 6.693825e-4
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 6.758042e-4
GO:0034122 negative regulation of toll-like receptor signaling pathway 6.758042e-4
GO:0050920 regulation of chemotaxis 6.846998e-4
GO:0009063 cellular amino acid catabolic process 6.883235e-4
GO:0045835 negative regulation of meiosis 7.077497e-4
GO:0042104 positive regulation of activated T cell proliferation 7.125669e-4
GO:0009056 catabolic process 7.324852e-4
GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly 7.349178e-4
GO:0002115 store-operated calcium entry 7.349178e-4
GO:0006690 icosanoid metabolic process 7.351605e-4
GO:0016486 peptide hormone processing 7.356780e-4
GO:0002483 antigen processing and presentation of endogenous peptide antigen 7.368527e-4
GO:0072594 establishment of protein localization to organelle 7.496911e-4
GO:0031658 negative regulation of cyclin-dependent protein kinase activity involved in G1/S 7.569057e-4
GO:0060290 transdifferentiation 7.569057e-4
GO:0007092 activation of mitotic anaphase-promoting complex activity 7.569057e-4
GO:0042742 defense response to bacterium 7.593797e-4
GO:0022904 respiratory electron transport chain 7.603914e-4
GO:0072521 purine-containing compound metabolic process 7.688313e-4
GO:0070613 regulation of protein processing 7.801147e-4
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation 7.853987e-4
GO:0010985 negative regulation of lipoprotein particle clearance 8.062748e-4
GO:0001932 regulation of protein phosphorylation 8.278151e-4
GO:0006644 phospholipid metabolic process 8.323420e-4
GO:0002700 regulation of production of molecular mediator of immune response 8.569174e-4
GO:0051246 regulation of protein metabolic process 8.715619e-4
GO:0006643 membrane lipid metabolic process 8.873367e-4
GO:0046655 folic acid metabolic process 9.113039e-4
GO:0030198 extracellular matrix organization 9.117150e-4
GO:0032355 response to estradiol stimulus 9.230005e-4
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 9.309542e-4
GO:0022417 protein maturation by protein folding 9.309542e-4
GO:0001835 blastocyst hatching 9.333820e-4
GO:0051494 negative regulation of cytoskeleton organization 9.362749e-4
GO:0061037 negative regulation of cartilage development 9.441561e-4
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 9.653560e-4
GO:0006195 purine nucleotide catabolic process 9.751650e-4
GO:0042345 regulation of NF-kappaB import into nucleus 9.779506e-4
GO:0009629 response to gravity 9.994011e-4
GO:0045047 protein targeting to ER 1.015841e-3
GO:0002697 regulation of immune effector process 1.017161e-3
GO:0006937 regulation of muscle contraction 1.019040e-3
GO:0043434 response to peptide hormone stimulus 1.020516e-3
GO:0019067 viral assembly, maturation, egress, and release 1.021010e-3
GO:0009725 response to hormone stimulus 1.040793e-3
GO:0050790 regulation of catalytic activity 1.053638e-3
GO:0006665 sphingolipid metabolic process 1.064223e-3
GO:0050709 negative regulation of protein secretion 1.068201e-3
GO:0008654 phospholipid biosynthetic process 1.101556e-3
GO:0051222 positive regulation of protein transport 1.104163e-3
GO:0010269 response to selenium ion 1.107889e-3
GO:0060444 branching involved in mammary gland duct morphogenesis 1.110913e-3
GO:0031657 regulation of cyclin-dependent protein kinase activity involved in G1/S 1.119588e-3
GO:0006620 posttranslational protein targeting to membrane 1.129640e-3
GO:0050776 regulation of immune response 1.134198e-3
GO:0050878 regulation of body fluid levels 1.147059e-3
GO:0035335 peptidyl-tyrosine dephosphorylation 1.147570e-3
GO:0032908 regulation of transforming growth factor beta1 production 1.155132e-3
GO:0002526 acute inflammatory response 1.168459e-3
GO:0050912 detection of chemical stimulus involved in sensory perception of taste 1.175390e-3
GO:0045471 response to ethanol 1.180792e-3
GO:0001736 establishment of planar polarity 1.215100e-3
GO:0002540 leukotriene production involved in inflammatory response 1.233736e-3
GO:0046340 diacylglycerol catabolic process 1.246418e-3
GO:0051592 response to calcium ion 1.248681e-3
GO:0051961 negative regulation of nervous system development 1.251990e-3
GO:0042534 regulation of tumor necrosis factor biosynthetic process 1.258192e-3
GO:0001935 endothelial cell proliferation 1.263260e-3
GO:0072539 T-helper 17 cell differentiation 1.266125e-3
GO:0032661 regulation of interleukin-18 production 1.266125e-3
GO:0006083 acetate metabolic process 1.266125e-3
GO:0045446 endothelial cell differentiation 1.271883e-3
GO:0010761 fibroblast migration 1.275846e-3
GO:0046466 membrane lipid catabolic process 1.284663e-3
GO:0032459 regulation of protein oligomerization 1.284663e-3
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin 1.294351e-3
GO:0006672 ceramide metabolic process 1.338494e-3
GO:0090066 regulation of anatomical structure size 1.347114e-3
GO:0060591 chondroblast differentiation 1.368536e-3
GO:0051896 regulation of protein kinase B signaling cascade 1.399624e-3
GO:0043200 response to amino acid stimulus 1.403171e-3
GO:0071363 cellular response to growth factor stimulus 1.407836e-3
GO:0046006 regulation of activated T cell proliferation 1.408346e-3
GO:0051135 positive regulation of NK T cell activation 1.412596e-3
GO:0071634 regulation of transforming growth factor beta production 1.434114e-3
GO:0042840 D-glucuronate catabolic process 1.498301e-3
GO:0044140 negative regulation of growth of symbiont on or near host surface 1.498301e-3
GO:0003096 renal sodium ion transport 1.498301e-3
GO:0002756 MyD88-independent toll-like receptor signaling pathway 1.498301e-3
GO:0032782 bile acid secretion 1.498301e-3
GO:0032387 negative regulation of intracellular transport 1.500730e-3
GO:0045429 positive regulation of nitric oxide biosynthetic process 1.509610e-3
GO:0042396 phosphagen biosynthetic process 1.516297e-3
GO:0022415 viral reproductive process 1.520113e-3
GO:0060068 vagina development 1.524389e-3
GO:0009628 response to abiotic stimulus 1.534246e-3
GO:0046686 response to cadmium ion 1.536178e-3
GO:0050810 regulation of steroid biosynthetic process 1.544024e-3
GO:0006406 mRNA export from nucleus 1.544941e-3
GO:0070340 detection of bacterial lipopeptide 1.571794e-3
GO:0002828 regulation of type 2 immune response 1.596317e-3
GO:0006568 tryptophan metabolic process 1.613541e-3
GO:0034382 chylomicron remnant clearance 1.630823e-3
GO:0010639 negative regulation of organelle organization 1.632132e-3
GO:0034377 plasma lipoprotein particle assembly 1.634632e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 1.642024e-3
GO:0001516 prostaglandin biosynthetic process 1.644713e-3
GO:2001021 negative regulation of response to DNA damage stimulus 1.644858e-3
GO:0031017 exocrine pancreas development 1.648618e-3
GO:0015802 basic amino acid transport 1.667064e-3
GO:0032425 positive regulation of mismatch repair 1.700619e-3
GO:0051451 myoblast migration 1.700619e-3
GO:0010912 positive regulation of isomerase activity 1.700619e-3
GO:0006939 smooth muscle contraction 1.715482e-3
GO:0031274 positive regulation of pseudopodium assembly 1.725730e-3
GO:2000146 negative regulation of cell motility 1.739030e-3
GO:0032501 multicellular organismal process 1.759366e-3
GO:0051461 positive regulation of corticotropin secretion 1.766611e-3
GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process 1.766611e-3
GO:0051445 regulation of meiotic cell cycle 1.791546e-3
GO:0070305 response to cGMP 1.796746e-3
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent 1.796746e-3
GO:0009071 serine family amino acid catabolic process 1.807905e-3
GO:0060340 positive regulation of type I interferon-mediated signaling pathway 1.813170e-3
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste 1.813170e-3
GO:0002275 myeloid cell activation involved in immune response 1.818575e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 1.824425e-3
GO:0002885 positive regulation of hypersensitivity 1.824425e-3
GO:0019441 tryptophan catabolic process to kynurenine 1.826220e-3
GO:0061098 positive regulation of protein tyrosine kinase activity 1.831918e-3
GO:0002675 positive regulation of acute inflammatory response 1.858211e-3
GO:0010565 regulation of cellular ketone metabolic process 1.876758e-3
GO:0032012 regulation of ARF protein signal transduction 1.885858e-3
GO:0006163 purine nucleotide metabolic process 1.893303e-3
GO:0006986 response to unfolded protein 1.896208e-3
GO:0050994 regulation of lipid catabolic process 1.919489e-3
GO:0001798 positive regulation of type IIa hypersensitivity 1.926581e-3
GO:0009450 gamma-aminobutyric acid catabolic process 1.934948e-3
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1.934948e-3
GO:0061077 chaperone-mediated protein folding 1.978819e-3
GO:0006693 prostaglandin metabolic process 1.989575e-3
GO:0034109 homotypic cell-cell adhesion 2.029474e-3
GO:0070972 protein localization in endoplasmic reticulum 2.055633e-3
GO:0052556 positive regulation by symbiont of host immune response 2.083748e-3
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 2.083748e-3
GO:0052509 positive regulation by symbiont of host defense response 2.083748e-3