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Novel motif:46

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name:motif46_CGNAGT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0006261 DNA-dependent DNA replication 3.422746e-11
GO:0006281 DNA repair 8.342762e-11
GO:0006283 transcription-coupled nucleotide-excision repair 1.876997e-10
GO:0000718 nucleotide-excision repair, DNA damage removal 2.501984e-9
GO:0071539 protein localization to centrosome 7.086213e-9
GO:0033299 secretion of lysosomal enzymes 1.570866e-8
GO:0050434 positive regulation of viral transcription 6.089444e-8
GO:2000465 regulation of glycogen (starch) synthase activity 7.024303e-8
GO:0021603 cranial nerve formation 1.064574e-7
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.567097e-7
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.862963e-7
GO:0030488 tRNA methylation 1.994214e-7
GO:0016032 viral reproduction 3.494463e-7
GO:0046628 positive regulation of insulin receptor signaling pathway 8.648641e-7
GO:0010224 response to UV-B 9.064211e-7
GO:0071460 cellular response to cell-matrix adhesion 9.459706e-7
GO:0009263 deoxyribonucleotide biosynthetic process 9.664895e-7
GO:0006289 nucleotide-excision repair 1.202662e-6
GO:0000216 M/G1 transition of mitotic cell cycle 1.209309e-6
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion 1.627810e-6
GO:0006412 translation 2.099886e-6
GO:0006370 mRNA capping 2.512698e-6
GO:0031573 intra-S DNA damage checkpoint 2.823050e-6
GO:0016071 mRNA metabolic process 2.907459e-6
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 3.082503e-6
GO:0006396 RNA processing 3.398728e-6
GO:0019264 glycine biosynthetic process from serine 4.514862e-6
GO:0070105 positive regulation of interleukin-6-mediated signaling pathway 5.937797e-6
GO:0006545 glycine biosynthetic process 6.088602e-6
GO:0006353 transcription termination, DNA-dependent 6.723153e-6
GO:0006308 DNA catabolic process 7.069869e-6
GO:0006368 transcription elongation from RNA polymerase II promoter 9.108650e-6
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 9.360138e-6
GO:0046782 regulation of viral transcription 1.001348e-5
GO:0035307 positive regulation of protein dephosphorylation 1.038252e-5
GO:0006270 DNA-dependent DNA replication initiation 1.150728e-5
GO:0006414 translational elongation 1.185481e-5
GO:0035306 positive regulation of dephosphorylation 1.198289e-5
GO:0006713 glucocorticoid catabolic process 1.215945e-5
GO:0042946 glucoside transport 1.215945e-5
GO:0014020 primary neural tube formation 1.445999e-5
GO:0032042 mitochondrial DNA metabolic process 1.548202e-5
GO:0006354 transcription elongation, DNA-dependent 2.029639e-5
GO:0035507 regulation of myosin-light-chain-phosphatase activity 2.286369e-5
GO:0009452 RNA capping 2.323839e-5
GO:0000398 nuclear mRNA splicing, via spliceosome 2.733281e-5
GO:0001843 neural tube closure 2.750817e-5
GO:0090031 positive regulation of steroid hormone biosynthetic process 2.787560e-5
GO:0032682 negative regulation of chemokine production 2.958776e-5
GO:0000725 recombinational repair 2.971587e-5
GO:0009186 deoxyribonucleoside diphosphate metabolic process 3.250101e-5
GO:0006119 oxidative phosphorylation 3.307815e-5
GO:0003409 optic cup structural organization 3.791750e-5
GO:0021623 oculomotor nerve formation 3.791750e-5
GO:0003404 optic vesicle morphogenesis 3.791750e-5
GO:0033108 mitochondrial respiratory chain complex assembly 3.854476e-5
GO:0006386 termination of RNA polymerase III transcription 4.074498e-5
GO:0006385 transcription elongation from RNA polymerase III promoter 4.074498e-5
GO:0000724 double-strand break repair via homologous recombination 4.297520e-5
GO:0006117 acetaldehyde metabolic process 4.765058e-5
GO:0033590 response to cobalamin 4.765058e-5
GO:0048790 maintenance of presynaptic active zone structure 4.765058e-5
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 4.765058e-5
GO:0000375 RNA splicing, via transesterification reactions 5.013045e-5
GO:0000084 S phase of mitotic cell cycle 5.067731e-5
GO:0060606 tube closure 5.156669e-5
GO:0015781 pyrimidine nucleotide-sugar transport 5.263381e-5
GO:0035304 regulation of protein dephosphorylation 5.523786e-5
GO:0065002 intracellular protein transmembrane transport 5.744536e-5
GO:0014040 positive regulation of Schwann cell differentiation 6.270961e-5
GO:0006268 DNA unwinding involved in replication 6.540090e-5
GO:0006264 mitochondrial DNA replication 6.649180e-5
GO:0051320 S phase 7.538309e-5
GO:0000022 mitotic spindle elongation 8.031923e-5
GO:0031297 replication fork processing 8.233790e-5
GO:0071281 cellular response to iron ion 8.601860e-5
GO:0034393 positive regulation of smooth muscle cell apoptosis 9.099136e-5
GO:0006349 regulation of gene expression by genetic imprinting 9.526584e-5
GO:0006413 translational initiation 1.006469e-4
GO:0060406 positive regulation of penile erection 1.075991e-4
GO:0031017 exocrine pancreas development 1.083607e-4
GO:0045333 cellular respiration 1.103496e-4
GO:0090232 positive regulation of spindle checkpoint 1.500529e-4
GO:0022027 interkinetic nuclear migration 1.560879e-4
GO:0071638 negative regulation of monocyte chemotactic protein-1 production 1.563801e-4
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 1.563801e-4
GO:0030150 protein import into mitochondrial matrix 1.563801e-4
GO:0035726 common myeloid progenitor cell proliferation 1.563801e-4
GO:0035732 nitric oxide storage 1.563801e-4
GO:0051645 Golgi localization 1.587310e-4
GO:0006290 pyrimidine dimer repair 1.631865e-4
GO:0006383 transcription from RNA polymerase III promoter 1.821472e-4
GO:0006458 'de novo' protein folding 1.934628e-4
GO:0048280 vesicle fusion with Golgi apparatus 1.985479e-4
GO:0001705 ectoderm formation 2.054820e-4
GO:0022616 DNA strand elongation 2.178940e-4
GO:0016446 somatic hypermutation of immunoglobulin genes 2.222828e-4
GO:0006450 regulation of translational fidelity 2.322601e-4
GO:0042249 establishment of planar polarity of embryonic epithelium 2.883476e-4
GO:0019323 pentose catabolic process 2.891536e-4
GO:0001830 trophectodermal cell fate commitment 2.891536e-4
GO:0006659 phosphatidylserine biosynthetic process 2.927165e-4
GO:0007020 microtubule nucleation 2.973105e-4
GO:0034126 positive regulation of MyD88-dependent toll-like receptor signaling pathway 2.990815e-4
GO:0006260 DNA replication 3.082848e-4
GO:0006313 transposition, DNA-mediated 3.249270e-4
GO:0015684 ferrous iron transport 3.443521e-4
GO:0042747 circadian sleep/wake cycle, REM sleep 3.557848e-4
GO:0035852 horizontal cell localization 3.557848e-4
GO:0045212 neurotransmitter receptor biosynthetic process 3.557848e-4
GO:2000768 positive regulation of nephron tubule epithelial cell differentiation 3.557848e-4
GO:0035846 oviduct epithelium development 3.557848e-4
GO:0032223 negative regulation of synaptic transmission, cholinergic 3.557848e-4
GO:0035849 nephric duct elongation 3.557848e-4
GO:0035502 metanephric ureteric bud development 3.557848e-4
GO:0035847 uterine epithelium development 3.557848e-4
GO:0048532 anatomical structure arrangement 3.761435e-4
GO:0008033 tRNA processing 3.881257e-4
GO:0090342 regulation of cell aging 3.975800e-4
GO:0034453 microtubule anchoring 4.010026e-4
GO:2000773 negative regulation of cellular senescence 4.387104e-4
GO:0043697 cell dedifferentiation 4.387104e-4
GO:0016574 histone ubiquitination 4.796377e-4
GO:0021658 rhombomere 3 morphogenesis 4.813649e-4
GO:0070170 regulation of tooth mineralization 4.937960e-4
GO:0006271 DNA strand elongation involved in DNA replication 4.963878e-4
GO:0009060 aerobic respiration 4.964786e-4
GO:0048524 positive regulation of viral reproduction 5.017994e-4
GO:0032784 regulation of transcription elongation, DNA-dependent 5.055341e-4
GO:0060457 negative regulation of digestive system process 5.109436e-4
GO:0021506 anterior neuropore closure 5.156563e-4
GO:0015789 UDP-N-acetylgalactosamine transport 5.272456e-4
GO:0015787 UDP-glucuronic acid transport 5.272456e-4
GO:0033683 nucleotide-excision repair, DNA incision 5.455653e-4
GO:0042732 D-xylose metabolic process 5.515574e-4
GO:0060005 vestibular reflex 5.517400e-4
GO:0090086 negative regulation of protein deubiquitination 5.599781e-4
GO:0010107 potassium ion import 5.737166e-4
GO:0006310 DNA recombination 6.438993e-4
GO:0051084 'de novo' posttranslational protein folding 6.550724e-4
GO:0043503 skeletal muscle fiber adaptation 6.556454e-4
GO:0043249 erythrocyte maturation 6.608822e-4
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 7.076184e-4
GO:0051318 G1 phase 7.219733e-4
GO:0003016 respiratory system process 7.880707e-4
GO:0016578 histone deubiquitination 8.104029e-4
GO:0006047 UDP-N-acetylglucosamine metabolic process 8.113592e-4
GO:0051096 positive regulation of helicase activity 8.154402e-4
GO:2000620 positive regulation of histone H4-K16 acetylation 8.249383e-4
GO:2000617 positive regulation of histone H3-K9 acetylation 8.249383e-4
GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response 8.249383e-4
GO:0070512 positive regulation of histone H4-K20 methylation 8.249383e-4
GO:0070946 neutrophil mediated killing of gram-positive bacterium 8.572660e-4
GO:0006482 protein demethylation 8.819109e-4
GO:0022613 ribonucleoprotein complex biogenesis 8.977886e-4
GO:0060455 negative regulation of gastric acid secretion 9.129566e-4
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway 9.129566e-4
GO:0006189 'de novo' IMP biosynthetic process 9.129566e-4
GO:0048752 semicircular canal morphogenesis 9.186716e-4
GO:0090344 negative regulation of cell aging 9.279832e-4
GO:0071514 genetic imprinting 9.560719e-4
GO:2000772 regulation of cellular senescence 1.005672e-3
GO:0051299 centrosome separation 1.018489e-3
GO:0000492 box C/D snoRNP assembly 1.018489e-3
GO:0000389 nuclear mRNA 3'-splice site recognition 1.049531e-3
GO:0016188 synaptic vesicle maturation 1.078277e-3
GO:0060405 regulation of penile erection 1.089101e-3
GO:0009436 glyoxylate catabolic process 1.182005e-3
GO:0032074 negative regulation of nuclease activity 1.183841e-3
GO:0050720 interleukin-1 beta biosynthetic process 1.183841e-3
GO:0031627 telomeric loop formation 1.183841e-3
GO:0007274 neuromuscular synaptic transmission 1.221748e-3
GO:0040040 thermosensory behavior 1.230800e-3
GO:0006476 protein deacetylation 1.247827e-3
GO:0000080 G1 phase of mitotic cell cycle 1.248626e-3
GO:0006473 protein acetylation 1.310742e-3
GO:0034470 ncRNA processing 1.336827e-3
GO:0032981 mitochondrial respiratory chain complex I assembly 1.393359e-3
GO:0035871 protein K11-linked deubiquitination 1.396947e-3
GO:0005984 disaccharide metabolic process 1.452045e-3
GO:0006172 ADP biosynthetic process 1.502751e-3
GO:0021796 cerebral cortex regionalization 1.511713e-3
GO:0035601 protein deacylation 1.511963e-3
GO:0031860 telomeric 3' overhang formation 1.544826e-3
GO:0031081 nuclear pore distribution 1.544826e-3
GO:0008052 sensory organ boundary specification 1.553947e-3
GO:0000082 G1/S transition of mitotic cell cycle 1.633237e-3
GO:0051497 negative regulation of stress fiber assembly 1.639516e-3
GO:0006853 carnitine shuttle 1.639516e-3
GO:0006369 termination of RNA polymerase II transcription 1.667685e-3
GO:0071843 cellular component biogenesis at cellular level 1.681722e-3
GO:0045176 apical protein localization 1.699434e-3
GO:0018202 peptidyl-histidine modification 1.699826e-3
GO:0042776 mitochondrial ATP synthesis coupled proton transport 1.701491e-3
GO:0019087 transformation of host cell by virus 1.720058e-3
GO:0090231 regulation of spindle checkpoint 1.751944e-3
GO:0045655 regulation of monocyte differentiation 1.751944e-3
GO:0046626 regulation of insulin receptor signaling pathway 1.805830e-3
GO:0043415 positive regulation of skeletal muscle tissue regeneration 1.813953e-3
GO:0032201 telomere maintenance via semi-conservative replication 1.823652e-3
GO:0051131 chaperone-mediated protein complex assembly 1.861457e-3
GO:0019303 D-ribose catabolic process 1.878592e-3
GO:0006400 tRNA modification 1.899082e-3
GO:0022618 ribonucleoprotein complex assembly 1.913120e-3
GO:0007184 SMAD protein import into nucleus 1.938836e-3
GO:0071826 ribonucleoprotein complex subunit organization 1.954787e-3
GO:0071557 histone H3-K27 demethylation 1.967982e-3
GO:0035574 histone H4-K20 demethylation 1.967982e-3
GO:0090085 regulation of protein deubiquitination 1.992436e-3
GO:0048205 COPI coating of Golgi vesicle 2.006347e-3
GO:0008380 RNA splicing 2.049161e-3
GO:0042254 ribosome biogenesis 2.064785e-3
GO:0006475 internal protein amino acid acetylation 2.135367e-3
GO:0006397 mRNA processing 2.135935e-3
GO:0000387 spliceosomal snRNP assembly 2.190179e-3
GO:0042775 mitochondrial ATP synthesis coupled electron transport 2.250896e-3
GO:0035845 photoreceptor cell outer segment organization 2.281824e-3
GO:0035305 negative regulation of dephosphorylation 2.344914e-3
GO:0060947 cardiac vascular smooth muscle cell differentiation 2.348861e-3
GO:0015788 UDP-N-acetylglucosamine transport 2.447104e-3
GO:0051083 'de novo' cotranslational protein folding 2.447104e-3
GO:0006348 chromatin silencing at telomere 2.447104e-3
GO:0009304 tRNA transcription 2.477991e-3
GO:0042637 catagen 2.549241e-3
GO:0016573 histone acetylation 2.716190e-3
GO:0060914 heart formation 2.746150e-3
GO:0015780 nucleotide-sugar transport 2.832283e-3
GO:0032581 ER-dependent peroxisome organization 2.947851e-3
GO:0042255 ribosome assembly 2.982821e-3
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 3.128001e-3
GO:0009265 2'-deoxyribonucleotide biosynthetic process 3.227843e-3
GO:0072111 cell proliferation involved in kidney development 3.298760e-3
GO:0045657 positive regulation of monocyte differentiation 3.299738e-3
GO:0006359 regulation of transcription from RNA polymerase III promoter 3.397823e-3
GO:0048194 Golgi vesicle budding 3.472283e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 3.567729e-3
GO:0022904 respiratory electron transport chain 3.701371e-3
GO:0034551 mitochondrial respiratory chain complex III assembly 3.736440e-3
GO:0045128 negative regulation of reciprocal meiotic recombination 3.736440e-3
GO:0006311 meiotic gene conversion 3.736440e-3
GO:0051549 positive regulation of keratinocyte migration 3.744152e-3
GO:0043543 protein acylation 3.749026e-3
GO:0070103 regulation of interleukin-6-mediated signaling pathway 3.807580e-3
GO:0045014 negative regulation of transcription by glucose 3.846432e-3
GO:0009133 nucleoside diphosphate biosynthetic process 3.854081e-3
GO:0021557 oculomotor nerve development 3.884685e-3
GO:0009262 deoxyribonucleotide metabolic process 3.923992e-3
GO:0071934 thiamine transmembrane transport 4.041840e-3
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 4.085180e-3
GO:0006099 tricarboxylic acid cycle 4.088957e-3
GO:0019532 oxalate transport 4.221305e-3
GO:0060575 intestinal epithelial cell differentiation 4.227954e-3
GO:0006564 L-serine biosynthetic process 4.333506e-3
GO:0019388 galactose catabolic process 4.411908e-3
GO:0080009 mRNA methylation 4.517430e-3
GO:0042450 arginine biosynthetic process via ornithine 4.517430e-3
GO:0014908 myotube differentiation involved in skeletal muscle regeneration 4.517430e-3
GO:0008049 male courtship behavior 4.517430e-3
GO:0006012 galactose metabolic process 4.522219e-3
GO:0006415 translational termination 4.630686e-3
GO:0006302 double-strand break repair 4.650328e-3
GO:0009202 deoxyribonucleoside triphosphate biosynthetic process 4.659410e-3
GO:0043309 regulation of eosinophil degranulation 4.659410e-3
GO:0010544 negative regulation of platelet activation 4.749395e-3
GO:0009153 purine deoxyribonucleotide biosynthetic process 4.813342e-3
GO:0002069 columnar/cuboidal epithelial cell maturation 4.813342e-3
GO:0046356 acetyl-CoA catabolic process 4.844235e-3
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 4.908131e-3
GO:0035566 regulation of metanephros size 4.908131e-3
GO:0008340 determination of adult lifespan 5.010169e-3
GO:0010923 negative regulation of phosphatase activity 5.136631e-3
GO:2000303 regulation of ceramide biosynthetic process 5.215879e-3
GO:0060574 intestinal epithelial cell maturation 5.239535e-3
GO:0060807 regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification 5.239535e-3
GO:0030421 defecation 5.239535e-3
GO:0035356 cellular triglyceride homeostasis 5.239535e-3
GO:0003142 cardiogenic plate morphogenesis 5.239535e-3
GO:0030952 establishment or maintenance of cytoskeleton polarity 5.305889e-3
GO:0006108 malate metabolic process 5.407565e-3
GO:0031848 protection from non-homologous end joining at telomere 5.489106e-3
GO:0070375 BMK cascade 5.489106e-3
GO:0060033 anatomical structure regression 5.549681e-3
GO:0035026 leading edge cell differentiation 5.673414e-3
GO:0009301 snRNA transcription 5.673414e-3
GO:0060301 positive regulation of cytokine activity 5.781427e-3
GO:0000710 meiotic mismatch repair 5.781427e-3
GO:2000300 regulation of synaptic vesicle exocytosis 5.789396e-3
GO:0048075 positive regulation of eye pigmentation 5.815257e-3
GO:0042481 regulation of odontogenesis 5.830404e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 5.908175e-3
GO:0032515 negative regulation of phosphoprotein phosphatase activity 5.979241e-3
GO:0006892 post-Golgi vesicle-mediated transport 5.987388e-3
GO:0006513 protein monoubiquitination 6.020223e-3
GO:0006974 response to DNA damage stimulus 6.054735e-3
GO:0051573 negative regulation of histone H3-K9 methylation 6.060695e-3
GO:0046730 induction of host immune response by virus 6.143932e-3
GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 6.143932e-3
GO:0090084 negative regulation of inclusion body assembly 6.179702e-3
GO:0032816 positive regulation of natural killer cell activation 6.205665e-3
GO:0032785 negative regulation of transcription elongation, DNA-dependent 6.322883e-3
GO:0051292 nuclear pore complex assembly 6.330536e-3
GO:0033131 regulation of glucokinase activity 6.382783e-3
GO:0021783 preganglionic parasympathetic nervous system development 6.403284e-3
GO:0043111 replication fork arrest 6.535690e-3
GO:0042840 D-glucuronate catabolic process 6.535690e-3
GO:0051684 maintenance of Golgi location 6.535690e-3
GO:0060921 sinoatrial node cell differentiation 6.535690e-3
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production 6.535690e-3
GO:0060975 cardioblast migration to the midline involved in heart field formation 6.535690e-3
GO:0042664 negative regulation of endodermal cell fate specification 6.535690e-3
GO:0003259 cardioblast anterior-lateral migration 6.535690e-3
GO:0003210 cardiac atrium formation 6.535690e-3
GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway 6.535690e-3
GO:0003241 growth involved in heart morphogenesis 6.535690e-3
GO:0003236 sinus venosus morphogenesis 6.535690e-3
GO:0032738 positive regulation of interleukin-15 production 6.535690e-3
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 6.535690e-3
GO:0009236 cobalamin biosynthetic process 6.535690e-3
GO:0070935 3'-UTR-mediated mRNA stabilization 6.584620e-3
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 6.657844e-3
GO:0021666 rhombomere 5 formation 6.686732e-3
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity 6.686732e-3
GO:0045090 retroviral genome replication 6.686732e-3
GO:0021660 rhombomere 3 formation 6.686732e-3
GO:0006175 dATP biosynthetic process 6.686732e-3
GO:0006478 peptidyl-tyrosine sulfation 6.686732e-3
GO:0021599 abducens nerve formation 6.714472e-3
GO:0007634 optokinetic behavior 6.714472e-3
GO:0051534 negative regulation of NFAT protein import into nucleus 6.773632e-3
GO:0048627 myoblast development 6.829664e-3
GO:0031936 negative regulation of chromatin silencing 6.874454e-3
GO:0015696 ammonium transport 7.081785e-3
GO:0051546 keratinocyte migration 7.174723e-3
GO:0018393 internal peptidyl-lysine acetylation 7.208216e-3
GO:0033132 negative regulation of glucokinase activity 7.303975e-3
GO:0006398 histone mRNA 3'-end processing 7.303975e-3
GO:0021591 ventricular system development 7.308165e-3
GO:0021569 rhombomere 3 development 7.310885e-3
GO:0051321 meiotic cell cycle 7.374728e-3
GO:0072300 positive regulation of metanephric glomerulus development 7.383891e-3
GO:0032637 interleukin-8 production 7.383891e-3
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 7.472737e-3
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 7.472737e-3
GO:0006548 histidine catabolic process 7.478702e-3
GO:0043241 protein complex disassembly 7.519574e-3
GO:0002041 intussusceptive angiogenesis 7.684057e-3
GO:0090104 pancreatic E cell differentiation 7.826931e-3
GO:0034509 centromeric core chromatin assembly 7.826931e-3
GO:0003311 pancreatic D cell differentiation 7.826931e-3
GO:0005998 xylulose catabolic process 7.826931e-3
GO:0021559 trigeminal nerve development 7.883302e-3
GO:0006044 N-acetylglucosamine metabolic process 7.910443e-3
GO:0018394 peptidyl-lysine acetylation 8.097685e-3
GO:0048102 autophagic cell death 8.499914e-3
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 8.652270e-3
GO:0006999 nuclear pore organization 8.652270e-3
GO:0042797 tRNA transcription from RNA polymerase III promoter 8.655129e-3
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 8.655129e-3
GO:2000111 positive regulation of macrophage apoptosis 8.730425e-3
GO:0014038 regulation of Schwann cell differentiation 8.764805e-3
GO:0048793 pronephros development 9.305625e-3
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 9.341374e-3
GO:0046655 folic acid metabolic process 9.343309e-3
GO:0009070 serine family amino acid biosynthetic process 9.468738e-3
GO:0007126 meiosis 9.724216e-3
GO:0050975 sensory perception of touch 9.838383e-3
GO:0016180 snRNA processing 9.873723e-3
GO:0071169 establishment of protein localization to chromatin 1.007647e-2
GO:0015919 peroxisomal membrane transport 1.007647e-2
GO:0006844 acyl carnitine transport 1.007647e-2
GO:0006756 AMP phosphorylation 1.007647e-2
GO:0006356 regulation of transcription from RNA polymerase I promoter 1.014933e-2
GO:0001302 replicative cell aging 1.014933e-2
GO:0003406 retinal pigment epithelium development 1.021641e-2
GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity 1.025423e-2
GO:0031129 inductive cell-cell signaling 1.025732e-2
GO:0090305 nucleic acid phosphodiester bond hydrolysis 1.028542e-2
GO:0070172 positive regulation of tooth mineralization 1.035518e-2
GO:0070366 regulation of hepatocyte differentiation 1.038127e-2
GO:0046502 uroporphyrinogen III metabolic process 1.038127e-2
GO:0009294 DNA mediated transformation 1.038127e-2
GO:0035308 negative regulation of protein dephosphorylation 1.048934e-2
GO:0060968 regulation of gene silencing 1.049393e-2
GO:0032230 positive regulation of synaptic transmission, GABAergic 1.050632e-2
GO:0006405 RNA export from nucleus 1.071199e-2
GO:0006298 mismatch repair 1.085312e-2
GO:0006901 vesicle coating 1.110836e-2
GO:0021670 lateral ventricle development 1.115365e-2
GO:0051492 regulation of stress fiber assembly 1.122685e-2
GO:0051882 mitochondrial depolarization 1.123657e-2
GO:0015822 ornithine transport 1.128648e-2
GO:2000304 positive regulation of ceramide biosynthetic process 1.131413e-2
GO:0006544 glycine metabolic process 1.141978e-2
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 1.150888e-2
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 1.168222e-2
GO:0016090 prenol metabolic process 1.175109e-2
GO:0009650 UV protection 1.182907e-2
GO:0035721 intraflagellar retrograde transport 1.198894e-2
GO:0048105 establishment of body hair planar orientation 1.200349e-2
GO:0060489 planar dichotomous subdivision of terminal units involved in lung branching morphogenesis 1.200349e-2
GO:0060490 lateral sprouting involved in lung morphogenesis 1.200349e-2
GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis 1.200349e-2
GO:0033484 nitric oxide homeostasis 1.215869e-2
GO:0090331 negative regulation of platelet aggregation 1.217012e-2
GO:0061110 dense core granule biogenesis 1.217012e-2
GO:2000971 negative regulation of detection of glucose 1.217012e-2
GO:2000976 regulation of transcription from RNA polymerase II promoter involved in detection of glucose 1.217012e-2
GO:0061108 seminal vesicle epithelium development 1.217012e-2
GO:0002115 store-operated calcium entry 1.217012e-2
GO:0000433 negative regulation of transcription from RNA polymerase II promoter by glucose 1.217012e-2
GO:0042628 mating plug formation 1.217012e-2
GO:0061034 olfactory bulb mitral cell layer development 1.228856e-2
GO:0051095 regulation of helicase activity 1.235135e-2
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 1.235871e-2
GO:0060576 intestinal epithelial cell development 1.237725e-2
GO:0060969 negative regulation of gene silencing 1.250450e-2
GO:0021602 cranial nerve morphogenesis 1.276782e-2
GO:0009132 nucleoside diphosphate metabolic process 1.324947e-2
GO:0009313 oligosaccharide catabolic process 1.330452e-2
GO:0006361 transcription initiation from RNA polymerase I promoter 1.341697e-2
GO:0035583 negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta 1.378462e-2
GO:0051414 response to cortisol stimulus 1.391677e-2
GO:0048619 embryonic hindgut morphogenesis 1.408180e-2
GO:0010587 miRNA catabolic process 1.408365e-2
GO:0017121 phospholipid scrambling 1.419106e-2
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 1.419679e-2
GO:0001510 RNA methylation 1.419982e-2
GO:0035166 post-embryonic hemopoiesis 1.420713e-2
GO:0030032 lamellipodium assembly 1.423105e-2
GO:0060040 retinal bipolar neuron differentiation 1.442967e-2
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 1.445236e-2
GO:0072177 mesonephric duct development 1.458494e-2
GO:0033092 positive regulation of immature T cell proliferation in thymus 1.458494e-2
GO:0060300 regulation of cytokine activity 1.463240e-2
GO:0000076 DNA replication checkpoint 1.463240e-2
GO:0060713 labyrinthine layer morphogenesis 1.473077e-2
GO:0042473 outer ear morphogenesis 1.489977e-2
GO:0010936 negative regulation of macrophage cytokine production 1.489977e-2
GO:0043624 cellular protein complex disassembly 1.490772e-2
GO:0032232 negative regulation of actin filament bundle assembly 1.509166e-2
GO:0006547 histidine metabolic process 1.531545e-2
GO:0031935 regulation of chromatin silencing 1.534808e-2
GO:0021575 hindbrain morphogenesis 1.548146e-2
GO:0032392 DNA geometric change 1.550499e-2
GO:0010520 regulation of reciprocal meiotic recombination 1.580153e-2
GO:0009443 pyridoxal 5'-phosphate salvage 1.580153e-2
GO:0032289 central nervous system myelin formation 1.601085e-2
GO:0003310 pancreatic A cell differentiation 1.615470e-2
GO:0048199 vesicle targeting, to, from or within Golgi 1.635044e-2
GO:0032200 telomere organization 1.648604e-2
GO:0015842 synaptic vesicle amine transport 1.648855e-2
GO:0000066 mitochondrial ornithine transport 1.648855e-2
GO:0051102 DNA ligation involved in DNA recombination 1.651742e-2
GO:2000009 negative regulation of protein localization at cell surface 1.651742e-2
GO:0043456 regulation of pentose-phosphate shunt 1.651742e-2
GO:0018192 enzyme active site formation via L-cysteine persulfide 1.651742e-2
GO:0060459 left lung development 1.689463e-2
GO:0033373 maintenance of protease location in mast cell secretory granule 1.689463e-2
GO:0033382 maintenance of granzyme B location in T cell secretory granule 1.689463e-2
GO:0035020 regulation of Rac protein signal transduction 1.702280e-2
GO:0060913 cardiac cell fate determination 1.714147e-2
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine 1.717880e-2
GO:0045351 type I interferon biosynthetic process 1.731608e-2
GO:2000109 regulation of macrophage apoptosis 1.740984e-2
GO:0010498 proteasomal protein catabolic process 1.749653e-2
GO:0071569 protein ufmylation 1.825846e-2
GO:0010739 positive regulation of protein kinase A signaling cascade 1.827896e-2
GO:0016577 histone demethylation 1.839970e-2
GO:0090103 cochlea morphogenesis 1.842190e-2
GO:0019079 viral genome replication 1.846853e-2
GO:0006297 nucleotide-excision repair, DNA gap filling 1.847225e-2
GO:0048242 epinephrine secretion 1.869957e-2
GO:0009785 blue light signaling pathway 1.869957e-2
GO:0070535 histone H2A K63-linked ubiquitination 1.873670e-2
GO:0006406 mRNA export from nucleus 1.880533e-2
GO:0006312 mitotic recombination 1.896610e-2
GO:0090042 tubulin deacetylation 1.898725e-2
GO:0070846 Hsp90 deacetylation 1.898725e-2
GO:0006272 leading strand elongation 1.898725e-2
GO:0060209 estrus 1.898725e-2
GO:0000715 nucleotide-excision repair, DNA damage recognition 1.908275e-2
GO:0090251 protein localization involved in establishment of planar polarity 1.923838e-2
GO:0060837 blood vessel endothelial cell differentiation 1.923838e-2
GO:0051325 interphase 1.938553e-2
GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 1.969013e-2
GO:0032288 myelin assembly 1.982858e-2
GO:0001778 plasma membrane repair 2.001947e-2
GO:0015074 DNA integration 2.030332e-2
GO:0009109 coenzyme catabolic process 2.034309e-2
GO:0016559 peroxisome fission 2.044009e-2
GO:0005993 trehalose catabolic process 2.044009e-2
GO:0090193 positive regulation of glomerulus development 2.052583e-2
GO:0010807 regulation of synaptic vesicle priming 2.055903e-2
GO:0048298 positive regulation of isotype switching to IgA isotypes 2.082355e-2
GO:0001710 mesodermal cell fate commitment 2.129362e-2
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 2.177810e-2
GO:0006670 sphingosine metabolic process 2.207881e-2
GO:0048203 vesicle targeting, trans-Golgi to endosome 2.212343e-2
GO:2000597 positive regulation of optic nerve formation 2.212343e-2
GO:0034633 retinol transport 2.212343e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0034660 ncRNA metabolic process 1.760748e-13
GO:0034470 ncRNA processing 1.721635e-11
GO:0043558 regulation of translational initiation in response to stress 8.022370e-10
GO:0006412 translation 4.814873e-9
GO:0035306 positive regulation of dephosphorylation 9.087238e-9
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 2.045558e-8
GO:0035307 positive regulation of protein dephosphorylation 2.111046e-8
GO:0043555 regulation of translation in response to stress 3.233639e-8
GO:0006399 tRNA metabolic process 2.509643e-7
GO:0050823 peptide antigen stabilization 2.670797e-7
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 2.670797e-7
GO:0008033 tRNA processing 4.640853e-7
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 5.029899e-7
GO:0032922 circadian regulation of gene expression 5.759897e-7
GO:0006396 RNA processing 1.153846e-6
GO:0051301 cell division 1.226822e-6
GO:0043243 positive regulation of protein complex disassembly 1.837924e-6
GO:0016180 snRNA processing 1.944588e-6
GO:0016073 snRNA metabolic process 2.399236e-6
GO:0000279 M phase 3.376694e-6
GO:0006680 glucosylceramide catabolic process 4.318542e-6
GO:0045626 negative regulation of T-helper 1 cell differentiation 4.709099e-6
GO:2000383 regulation of ectoderm development 5.310049e-6
GO:0021681 cerebellar granular layer development 6.644359e-6
GO:0090086 negative regulation of protein deubiquitination 1.253739e-5
GO:0006413 translational initiation 1.706419e-5
GO:0002678 positive regulation of chronic inflammatory response 2.113837e-5
GO:0008053 mitochondrial fusion 2.198414e-5
GO:0044260 cellular macromolecule metabolic process 2.459751e-5
GO:0090084 negative regulation of inclusion body assembly 2.930023e-5
GO:2000384 negative regulation of ectoderm development 3.001681e-5
GO:0010616 negative regulation of cardiac muscle adaptation 3.472804e-5
GO:0055119 relaxation of cardiac muscle 3.500357e-5
GO:0010950 positive regulation of endopeptidase activity 3.500357e-5
GO:0032515 negative regulation of phosphoprotein phosphatase activity 3.822219e-5
GO:0021707 cerebellar granule cell differentiation 3.998777e-5
GO:0060948 cardiac vascular smooth muscle cell development 4.475962e-5
GO:0046069 cGMP catabolic process 5.179462e-5
GO:0071267 L-methionine salvage 5.342427e-5
GO:0008616 queuosine biosynthetic process 5.689350e-5
GO:0021683 cerebellar granular layer morphogenesis 5.839992e-5
GO:0032467 positive regulation of cytokinesis 6.674181e-5
GO:0019509 L-methionine salvage from methylthioadenosine 7.858245e-5
GO:0051901 positive regulation of mitochondrial depolarization 8.327699e-5
GO:0045750 positive regulation of S phase of mitotic cell cycle 8.327699e-5
GO:0048284 organelle fusion 8.421010e-5
GO:0032218 riboflavin transport 8.939492e-5
GO:0090140 regulation of mitochondrial fission 9.103939e-5
GO:0008617 guanosine metabolic process 9.103939e-5
GO:0060124 positive regulation of growth hormone secretion 9.649696e-5
GO:0006625 protein targeting to peroxisome 1.091889e-4
GO:0035304 regulation of protein dephosphorylation 1.165191e-4
GO:0032465 regulation of cytokinesis 1.216119e-4
GO:0007067 mitosis 1.222183e-4
GO:0010833 telomere maintenance via telomere lengthening 1.256494e-4
GO:0000059 protein import into nucleus, docking 1.323505e-4
GO:0034587 piRNA metabolic process 1.330810e-4
GO:0090085 regulation of protein deubiquitination 1.420487e-4
GO:0006430 lysyl-tRNA aminoacylation 1.665348e-4
GO:0048239 negative regulation of DNA recombination at telomere 1.665348e-4
GO:2000296 negative regulation of hydrogen peroxide catabolic process 1.665348e-4
GO:0033617 mitochondrial respiratory chain complex IV assembly 1.665348e-4
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 1.670745e-4
GO:0032516 positive regulation of phosphoprotein phosphatase activity 1.671400e-4
GO:0046986 negative regulation of hemoglobin biosynthetic process 1.738038e-4
GO:0015969 guanosine tetraphosphate metabolic process 1.738038e-4
GO:0070265 necrotic cell death 1.739870e-4
GO:0000087 M phase of mitotic cell cycle 2.285384e-4
GO:0090231 regulation of spindle checkpoint 2.637114e-4
GO:0055118 negative regulation of cardiac muscle contraction 2.670771e-4
GO:0007049 cell cycle 2.704263e-4
GO:0051220 cytoplasmic sequestering of protein 2.718801e-4
GO:0030163 protein catabolic process 2.720501e-4
GO:0010467 gene expression 2.742873e-4
GO:0018023 peptidyl-lysine trimethylation 2.812111e-4
GO:0006354 transcription elongation, DNA-dependent 2.831771e-4
GO:0090141 positive regulation of mitochondrial fission 3.046086e-4
GO:0006259 DNA metabolic process 3.167217e-4
GO:0006414 translational elongation 3.250830e-4
GO:0090304 nucleic acid metabolic process 3.654342e-4
GO:0051135 positive regulation of NK T cell activation 4.161614e-4
GO:0048285 organelle fission 4.207498e-4
GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development 4.545834e-4
GO:0002030 inhibitory G-protein coupled receptor phosphorylation 4.545834e-4
GO:0030719 P granule organization 4.545834e-4
GO:0031129 inductive cell-cell signaling 4.982684e-4
GO:0032057 negative regulation of translational initiation in response to stress 4.982684e-4
GO:0008611 ether lipid biosynthetic process 4.982684e-4
GO:0019285 glycine betaine biosynthetic process from choline 5.098476e-4
GO:0070935 3'-UTR-mediated mRNA stabilization 5.419078e-4
GO:0006352 transcription initiation, DNA-dependent 5.570845e-4
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 5.699003e-4
GO:0000379 tRNA-type intron splice site recognition and cleavage 5.910311e-4
GO:0014745 negative regulation of muscle adaptation 6.056767e-4
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 6.108777e-4
GO:0021578 hindbrain maturation 6.976103e-4
GO:0016558 protein import into peroxisome matrix 7.221996e-4
GO:0007076 mitotic chromosome condensation 7.330632e-4
GO:0021750 vestibular nucleus development 7.432719e-4
GO:0021679 cerebellar molecular layer development 7.432719e-4
GO:0021590 cerebellum maturation 7.432719e-4
GO:0016078 tRNA catabolic process 8.530840e-4
GO:0001682 tRNA 5'-leader removal 8.530840e-4
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 8.715810e-4
GO:0006366 transcription from RNA polymerase II promoter 8.858876e-4
GO:0006919 activation of caspase activity 8.867637e-4
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 8.941521e-4
GO:0035095 behavioral response to nicotine 8.980100e-4
GO:0008634 negative regulation of survival gene product expression 9.063042e-4
GO:0097084 vascular smooth muscle cell development 9.107503e-4
GO:0021933 radial glia guided migration of cerebellar granule cell 9.489407e-4
GO:0008380 RNA splicing 9.570905e-4
GO:0000209 protein polyubiquitination 9.738010e-4
GO:0048255 mRNA stabilization 9.987309e-4
GO:0006289 nucleotide-excision repair 1.038762e-3
GO:0060458 right lung development 1.074693e-3
GO:0006172 ADP biosynthetic process 1.074693e-3
GO:0006094 gluconeogenesis 1.219440e-3
GO:2000381 negative regulation of mesoderm development 1.269283e-3
GO:0010991 negative regulation of SMAD protein complex assembly 1.269283e-3
GO:0032055 negative regulation of translation in response to stress 1.299745e-3
GO:0015991 ATP hydrolysis coupled proton transport 1.307673e-3
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1.308498e-3
GO:0060282 positive regulation of oocyte development 1.376207e-3
GO:0060281 regulation of oocyte development 1.376207e-3
GO:0046479 glycosphingolipid catabolic process 1.428614e-3
GO:0006578 betaine biosynthetic process 1.428614e-3
GO:0008535 respiratory chain complex IV assembly 1.454008e-3
GO:0007099 centriole replication 1.459517e-3
GO:0001522 pseudouridine synthesis 1.461938e-3
GO:0033108 mitochondrial respiratory chain complex assembly 1.497957e-3
GO:0042851 L-alanine metabolic process 1.508392e-3
GO:0006888 ER to Golgi vesicle-mediated transport 1.532535e-3
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 1.562701e-3
GO:0046477 glycosylceramide catabolic process 1.629131e-3
GO:0070198 protein localization to chromosome, telomeric region 1.629131e-3
GO:0042994 cytoplasmic sequestering of transcription factor 1.714299e-3
GO:0006984 ER-nucleus signaling pathway 1.741869e-3
GO:0008063 Toll signaling pathway 1.783674e-3
GO:0006264 mitochondrial DNA replication 1.807248e-3
GO:0032933 SREBP-mediated signaling pathway 1.841443e-3
GO:0006657 CDP-choline pathway 1.863969e-3
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 1.867170e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1.867170e-3
GO:0032784 regulation of transcription elongation, DNA-dependent 1.918913e-3
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 1.928033e-3
GO:0050883 musculoskeletal movement, spinal reflex action 2.040934e-3
GO:0046639 negative regulation of alpha-beta T cell differentiation 2.058961e-3
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 2.090571e-3
GO:0043094 cellular metabolic compound salvage 2.094102e-3
GO:0007140 male meiosis 2.216494e-3
GO:0032785 negative regulation of transcription elongation, DNA-dependent 2.238524e-3
GO:0006266 DNA ligation 2.320339e-3
GO:0007028 cytoplasm organization 2.340578e-3
GO:0006863 purine base transport 2.370490e-3
GO:0071103 DNA conformation change 2.533694e-3
GO:0035865 cellular response to potassium ion 2.551285e-3
GO:0043181 vacuolar sequestering 2.551285e-3
GO:0034651 cortisol biosynthetic process 2.551285e-3
GO:0006427 histidyl-tRNA aminoacylation 2.551285e-3
GO:0006409 tRNA export from nucleus 2.551285e-3
GO:0015966 diadenosine tetraphosphate biosynthetic process 2.551285e-3
GO:0034502 protein localization to chromosome 2.577724e-3
GO:0031065 positive regulation of histone deacetylation 2.729839e-3
GO:0019319 hexose biosynthetic process 2.754210e-3
GO:0010457 centriole-centriole cohesion 2.758672e-3
GO:0016081 synaptic vesicle docking involved in exocytosis 2.789072e-3
GO:0014051 gamma-aminobutyric acid secretion 2.839218e-3
GO:0000733 DNA strand renaturation 3.008496e-3
GO:0045964 positive regulation of dopamine metabolic process 3.020724e-3
GO:0032226 positive regulation of synaptic transmission, dopaminergic 3.020724e-3
GO:0042254 ribosome biogenesis 3.113760e-3
GO:0046129 purine ribonucleoside biosynthetic process 3.161039e-3
GO:0045919 positive regulation of cytolysis 3.210242e-3
GO:0032342 aldosterone biosynthetic process 3.263394e-3
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 3.263394e-3
GO:0003127 detection of nodal flow 3.263394e-3
GO:0009589 detection of UV 3.263394e-3
GO:0051298 centrosome duplication 3.390542e-3
GO:0031848 protection from non-homologous end joining at telomere 3.397256e-3
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 3.397256e-3
GO:0002175 protein localization to paranode region of axon 3.477048e-3
GO:0006577 betaine metabolic process 3.635166e-3
GO:0060123 regulation of growth hormone secretion 3.643853e-3
GO:0023021 termination of signal transduction 3.671037e-3
GO:2000117 negative regulation of cysteine-type endopeptidase activity 3.967708e-3
GO:0007228 positive regulation of hh target transcription factor activity 3.967708e-3
GO:0090312 positive regulation of protein deacetylation 4.055465e-3
GO:0030644 cellular chloride ion homeostasis 4.067582e-3
GO:0060266 negative regulation of respiratory burst involved in inflammatory response 4.089689e-3
GO:0006540 glutamate decarboxylation to succinate 4.089689e-3
GO:0034214 protein hexamerization 4.379842e-3
GO:0001778 plasma membrane repair 4.406880e-3
GO:0006368 transcription elongation from RNA polymerase II promoter 4.423254e-3
GO:0002483 antigen processing and presentation of endogenous peptide antigen 4.423254e-3
GO:0031497 chromatin assembly 4.433041e-3
GO:0006778 porphyrin-containing compound metabolic process 4.501586e-3
GO:0022402 cell cycle process 4.633007e-3
GO:0021697 cerebellar cortex formation 4.635557e-3
GO:0006555 methionine metabolic process 4.637736e-3
GO:0000002 mitochondrial genome maintenance 4.637736e-3
GO:0065004 protein-DNA complex assembly 4.793462e-3
GO:0060459 left lung development 4.814505e-3
GO:0003065 positive regulation of heart rate by epinephrine 4.817982e-3
GO:2000062 negative regulation of ureter smooth muscle cell differentiation 4.834011e-3
GO:0080125 multicellular structure septum development 4.834011e-3
GO:2000358 positive regulation of kidney smooth muscle cell differentiation 4.834011e-3
GO:0060783 mesenchymal smoothened signaling pathway involved in prostate gland development 4.834011e-3
GO:2000357 negative regulation of kidney smooth muscle cell differentiation 4.834011e-3
GO:2000063 positive regulation of ureter smooth muscle cell differentiation 4.834011e-3
GO:0035562 negative regulation of chromatin binding 4.834011e-3
GO:0000415 negative regulation of histone H3-K36 methylation 4.834011e-3
GO:0007502 digestive tract mesoderm development 4.834011e-3
GO:0014858 positive regulation of skeletal muscle cell proliferation 4.834011e-3
GO:0046534 positive regulation of photoreceptor cell differentiation 4.834011e-3
GO:0060782 regulation of mesenchymal cell proliferation involved in prostate gland development 4.834011e-3
GO:0000723 telomere maintenance 4.860805e-3
GO:0070842 aggresome assembly 4.917237e-3
GO:0046984 regulation of hemoglobin biosynthetic process 4.917237e-3
GO:0016539 intein-mediated protein splicing 4.917237e-3
GO:0043488 regulation of mRNA stability 5.063241e-3
GO:0000819 sister chromatid segregation 5.080578e-3
GO:0045780 positive regulation of bone resorption 5.121949e-3
GO:0000079 regulation of cyclin-dependent protein kinase activity 5.199657e-3
GO:0032200 telomere organization 5.223860e-3
GO:0042335 cuticle development 5.406991e-3
GO:0043048 dolichyl monophosphate biosynthetic process 5.406991e-3
GO:0071279 cellular response to cobalt ion 5.406991e-3
GO:0035364 thymine transport 5.406991e-3
GO:0035344 hypoxanthine transport 5.406991e-3
GO:0015853 adenine transport 5.406991e-3
GO:0015854 guanine transport 5.406991e-3
GO:0010637 negative regulation of mitochondrial fusion 5.406991e-3
GO:0045623 negative regulation of T-helper cell differentiation 5.451832e-3
GO:0003322 pancreatic A cell development 5.511187e-3
GO:0021905 forebrain-midbrain boundary formation 5.511187e-3
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 5.511187e-3
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 5.511187e-3
GO:0032981 mitochondrial respiratory chain complex I assembly 5.552802e-3
GO:0030320 cellular monovalent inorganic anion homeostasis 5.552802e-3
GO:0006308 DNA catabolic process 5.561747e-3
GO:0006260 DNA replication 5.620172e-3
GO:0032446 protein modification by small protein conjugation 5.667141e-3
GO:0010719 negative regulation of epithelial to mesenchymal transition 5.815247e-3
GO:0072355 histone H3-T3 phosphorylation 5.818374e-3
GO:0090042 tubulin deacetylation 5.818374e-3
GO:0070846 Hsp90 deacetylation 5.818374e-3
GO:0031119 tRNA pseudouridine synthesis 5.818374e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 5.818374e-3
GO:0042228 interleukin-8 biosynthetic process 5.818374e-3
GO:0009215 purine deoxyribonucleoside triphosphate metabolic process 5.874329e-3
GO:0000422 mitochondrion degradation 5.903626e-3
GO:0006006 glucose metabolic process 5.948898e-3
GO:0044237 cellular metabolic process 5.986268e-3
GO:0001302 replicative cell aging 6.006764e-3
GO:0001834 trophectodermal cell proliferation 6.016634e-3
GO:0071539 protein localization to centrosome 6.016634e-3
GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 6.131397e-3
GO:0000738 DNA catabolic process, exonucleolytic 6.144549e-3
GO:0048168 regulation of neuronal synaptic plasticity 6.161028e-3
GO:0006511 ubiquitin-dependent protein catabolic process 6.186004e-3
GO:0006139 nucleobase-containing compound metabolic process 6.186065e-3
GO:0048102 autophagic cell death 6.225063e-3
GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development 6.228753e-3
GO:0061034 olfactory bulb mitral cell layer development 6.228753e-3
GO:0045630 positive regulation of T-helper 2 cell differentiation 6.228753e-3
GO:0000070 mitotic sister chromatid segregation 6.327848e-3
GO:0045647 negative regulation of erythrocyte differentiation 6.450480e-3
GO:0045625 regulation of T-helper 1 cell differentiation 6.590565e-3
GO:0006906 vesicle fusion 6.650981e-3
GO:0019941 modification-dependent protein catabolic process 6.698976e-3
GO:0043632 modification-dependent macromolecule catabolic process 6.805027e-3
GO:0015931 nucleobase-containing compound transport 6.812788e-3
GO:0009086 methionine biosynthetic process 6.824882e-3
GO:0050658 RNA transport 7.023859e-3
GO:0045948 positive regulation of translational initiation 7.144215e-3
GO:0010952 positive regulation of peptidase activity 7.157974e-3
GO:0048842 positive regulation of axon extension involved in axon guidance 7.375665e-3
GO:0045875 negative regulation of sister chromatid cohesion 7.375665e-3
GO:0051103 DNA ligation involved in DNA repair 7.418637e-3
GO:0006281 DNA repair 7.440361e-3
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 7.663083e-3
GO:0072017 distal tubule development 7.672888e-3
GO:0015986 ATP synthesis coupled proton transport 7.672888e-3
GO:0021853 cerebral cortex GABAergic interneuron migration 7.818152e-3
GO:0014056 regulation of acetylcholine secretion 7.848395e-3
GO:0033091 positive regulation of immature T cell proliferation 7.848395e-3
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 7.848395e-3
GO:0032205 negative regulation of telomere maintenance 7.848395e-3
GO:0045908 negative regulation of vasodilation 7.956307e-3
GO:0033092 positive regulation of immature T cell proliferation in thymus 7.956307e-3
GO:0042168 heme metabolic process 7.986018e-3
GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 8.031712e-3
GO:0030913 paranodal junction assembly 8.271355e-3
GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 8.294464e-3
GO:0010165 response to X-ray 8.346172e-3
GO:0001840 neural plate development 8.634412e-3
GO:0009648 photoperiodism 8.669651e-3
GO:0015851 nucleobase transport 8.691562e-3
GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing 8.832948e-3
GO:0033572 transferrin transport 8.832948e-3
GO:0009107 lipoate biosynthetic process 8.832948e-3
GO:0006437 tyrosyl-tRNA aminoacylation 8.832948e-3
GO:0061025 membrane fusion 8.932831e-3
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 9.040027e-3
GO:0007141 male meiosis I 9.144486e-3
GO:0051900 regulation of mitochondrial depolarization 9.277967e-3
GO:0007080 mitotic metaphase plate congression 9.373913e-3
GO:0006090 pyruvate metabolic process 9.412489e-3
GO:0071603 endothelial cell-cell adhesion 9.505825e-3
GO:0051028 mRNA transport 9.919841e-3
GO:0048341 paraxial mesoderm formation 9.983630e-3
GO:0071922 regulation of cohesin localization to chromatin 1.004208e-2
GO:0051583 dopamine uptake 1.018603e-2
GO:0021843 substrate-independent telencephalic tangential interneuron migration 1.018766e-2
GO:2000016 negative regulation of determination of dorsal identity 1.025879e-2
GO:0000722 telomere maintenance via recombination 1.025879e-2
GO:0009451 RNA modification 1.034257e-2
GO:0007031 peroxisome organization 1.034506e-2
GO:0046604 positive regulation of mitotic centrosome separation 1.052953e-2
GO:0034276 kynurenic acid biosynthetic process 1.052953e-2
GO:0032298 positive regulation of DNA-dependent DNA replication initiation 1.052953e-2
GO:0002534 cytokine production involved in inflammatory response 1.052953e-2
GO:0071843 cellular component biogenesis at cellular level 1.069397e-2
GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport 1.080489e-2
GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly 1.080489e-2
GO:0033603 positive regulation of dopamine secretion 1.080489e-2
GO:0007051 spindle organization 1.084154e-2
GO:0006944 cellular membrane fusion 1.100541e-2
GO:0042136 neurotransmitter biosynthetic process 1.105429e-2
GO:0035564 regulation of kidney size 1.113415e-2
GO:0043487 regulation of RNA stability 1.116260e-2
GO:0021895 cerebral cortex neuron differentiation 1.132198e-2
GO:0071824 protein-DNA complex subunit organization 1.146044e-2
GO:0006119 oxidative phosphorylation 1.153576e-2
GO:0061113 pancreas morphogenesis 1.159309e-2
GO:0090342 regulation of cell aging 1.159816e-2
GO:0046329 negative regulation of JNK cascade 1.159816e-2
GO:0022403 cell cycle phase 1.189387e-2
GO:0006364 rRNA processing 1.197316e-2
GO:0000729 DNA double-strand break processing 1.205905e-2
GO:0021997 neural plate axis specification 1.205905e-2
GO:0000414 regulation of histone H3-K36 methylation 1.205905e-2
GO:0042760 very long-chain fatty acid catabolic process 1.209433e-2
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing 1.209433e-2
GO:0034379 very-low-density lipoprotein particle assembly 1.209433e-2
GO:0031575 mitotic cell cycle G1/S transition checkpoint 1.209750e-2
GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway 1.221173e-2
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 1.221234e-2
GO:0071777 positive regulation of cell cycle cytokinesis 1.228620e-2
GO:0016567 protein ubiquitination 1.230286e-2
GO:0035385 Roundabout signaling pathway 1.253280e-2
GO:0003062 regulation of heart rate by chemical signal 1.258698e-2
GO:0009950 dorsal/ventral axis specification 1.267674e-2
GO:0072240 metanephric DCT cell differentiation 1.276354e-2
GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development 1.276354e-2
GO:0072227 metanephric macula densa development 1.276354e-2
GO:2000172 regulation of branching morphogenesis of a nerve 1.287424e-2
GO:0006403 RNA localization 1.297273e-2
GO:0032277 negative regulation of gonadotropin secretion 1.306356e-2
GO:0016070 RNA metabolic process 1.306592e-2
GO:0090096 positive regulation of metanephric cap mesenchymal cell proliferation 1.307215e-2
GO:0060947 cardiac vascular smooth muscle cell differentiation 1.332669e-2
GO:0035695 mitochondrion degradation by induced vacuole formation 1.335357e-2
GO:0009217 purine deoxyribonucleoside triphosphate catabolic process 1.335357e-2
GO:0000492 box C/D snoRNP assembly 1.335357e-2
GO:0033013 tetrapyrrole metabolic process 1.382488e-2
GO:0045624 positive regulation of T-helper cell differentiation 1.394252e-2
GO:0006323 DNA packaging 1.398771e-2
GO:0051297 centrosome organization 1.401637e-2
GO:2000045 regulation of G1/S transition of mitotic cell cycle 1.408043e-2
GO:0021587 cerebellum morphogenesis 1.415728e-2
GO:0008637 apoptotic mitochondrial changes 1.419988e-2
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1.432169e-2
GO:0006333 chromatin assembly or disassembly 1.435805e-2
GO:0001504 neurotransmitter uptake 1.448280e-2
GO:0030502 negative regulation of bone mineralization 1.477913e-2
GO:0006779 porphyrin-containing compound biosynthetic process 1.495534e-2
GO:0035640 exploration behavior 1.521518e-2
GO:0016071 mRNA metabolic process 1.527261e-2
GO:0070171 negative regulation of tooth mineralization 1.528169e-2
GO:0042697 menopause 1.528169e-2
GO:0018242 protein O-linked glycosylation via serine 1.528169e-2
GO:0018243 protein O-linked glycosylation via threonine 1.528169e-2
GO:0045906 negative regulation of vasoconstriction 1.547641e-2
GO:0006538 glutamate catabolic process 1.547641e-2
GO:0032836 glomerular basement membrane development 1.547641e-2
GO:0042053 regulation of dopamine metabolic process 1.554551e-2
GO:0000726 non-recombinational repair 1.554551e-2
GO:0000096 sulfur amino acid metabolic process 1.557543e-2
GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification 1.607392e-2
GO:0030836 positive regulation of actin filament depolymerization 1.607392e-2
GO:0034641 cellular nitrogen compound metabolic process 1.612272e-2
GO:0071786 endoplasmic reticulum tubular network organization 1.625484e-2
GO:0034553 mitochondrial respiratory chain complex II assembly 1.625484e-2
GO:0006561 proline biosynthetic process 1.634414e-2
GO:0018283 iron incorporation into metallo-sulfur cluster 1.634414e-2
GO:0015855 pyrimidine base transport 1.634414e-2
GO:0002828 regulation of type 2 immune response 1.656397e-2
GO:0060264 regulation of respiratory burst involved in inflammatory response 1.681401e-2
GO:0070669 response to interleukin-2 1.681401e-2
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1.681401e-2
GO:0021568 rhombomere 2 development 1.681401e-2
GO:0007529 establishment of synaptic specificity at neuromuscular junction 1.681401e-2
GO:0010569 regulation of double-strand break repair via homologous recombination 1.695300e-2
GO:0009067 aspartate family amino acid biosynthetic process 1.699448e-2
GO:0051321 meiotic cell cycle 1.736066e-2
GO:0021575 hindbrain morphogenesis 1.737917e-2
GO:0051603 proteolysis involved in cellular protein catabolic process 1.805513e-2
GO:0006367 transcription initiation from RNA polymerase II promoter 1.838647e-2
GO:0046854 phosphatidylinositol phosphorylation 1.844332e-2
GO:0006261 DNA-dependent DNA replication 1.868958e-2
GO:0045628 regulation of T-helper 2 cell differentiation 1.874014e-2
GO:0021877 forebrain neuron fate commitment 1.874014e-2
GO:0060125 negative regulation of growth hormone secretion 1.878114e-2
GO:0072249 metanephric glomerular visceral epithelial cell development 1.878114e-2
GO:0072274 metanephric glomerular basement membrane development 1.878114e-2
GO:2000009 negative regulation of protein localization at cell surface 1.878114e-2
GO:0048677 axon extension involved in regeneration 1.878114e-2
GO:0051463 negative regulation of cortisol secretion 1.878114e-2
GO:0009443 pyridoxal 5'-phosphate salvage 1.878114e-2
GO:0003026 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback 1.878114e-2
GO:0021771 lateral geniculate nucleus development 1.878114e-2
GO:0070168 negative regulation of biomineral tissue development 1.878426e-2
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 1.878426e-2
GO:0034105 positive regulation of tissue remodeling 1.896399e-2
GO:0042069 regulation of catecholamine metabolic process 1.911702e-2
GO:0045023 G0 to G1 transition 1.920146e-2
GO:0070194 synaptonemal complex disassembly 1.920146e-2
GO:0070368 positive regulation of hepatocyte differentiation 1.920146e-2
GO:0048313 Golgi inheritance 1.920146e-2
GO:0043046 DNA methylation involved in gamete generation 1.920165e-2
GO:0031063 regulation of histone deacetylation 1.922345e-2
GO:0044257 cellular protein catabolic process 1.925567e-2
GO:0035308 negative regulation of protein dephosphorylation 1.940937e-2
GO:0007052 mitotic spindle organization 1.951167e-2
GO:0043280 positive regulation of caspase activity 1.983612e-2
GO:0061003 positive regulation of dendritic spine morphogenesis 1.984281e-2
GO:0000959 mitochondrial RNA metabolic process 2.026169e-2
GO:0035967 cellular response to topologically incorrect protein 2.029965e-2
GO:0006105 succinate metabolic process 2.033702e-2
GO:0046060 dATP metabolic process 2.066297e-2
GO:0072236 metanephric loop of Henle development 2.086509e-2
GO:0043153 entrainment of circadian clock by photoperiod 2.096044e-2
GO:0060829 negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation 2.116718e-2
GO:0070922 small RNA loading onto RISC 2.116718e-2
GO:0060381 positive regulation of single-stranded telomeric DNA binding 2.116718e-2
GO:0035750 protein localization to myelin sheath abaxonal region 2.116718e-2
GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific 2.116718e-2
GO:0009057 macromolecule catabolic process 2.127187e-2
GO:0050925 negative regulation of negative chemotaxis 2.131194e-2
GO:0010936 negative regulation of macrophage cytokine production 2.131194e-2
GO:0021903 rostrocaudal neural tube patterning 2.144116e-2
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 2.155127e-2
GO:0090403 oxidative stress-induced premature senescence 2.158088e-2
GO:0046322 negative regulation of fatty acid oxidation 2.158088e-2
GO:0060060 post-embryonic retina morphogenesis in camera-type eye 2.164383e-2
GO:0070166 enamel mineralization 2.164383e-2
GO:0032808 lacrimal gland development 2.187233e-2
GO:0007098 centrosome cycle 2.208744e-2
GO:0032222 regulation of synaptic transmission, cholinergic 2.241067e-2
GO:0060405 regulation of penile erection 2.261338e-2
GO:0060046 regulation of acrosome reaction 2.261338e-2
GO:0009798 axis specification 2.271754e-2
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 2.291568e-2
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 2.291568e-2
GO:0006390 transcription from mitochondrial promoter 2.291568e-2
GO:0000413 protein peptidyl-prolyl isomerization 2.301247e-2
GO:0021696 cerebellar cortex morphogenesis 2.331342e-2
GO:0009200 deoxyribonucleoside triphosphate metabolic process 2.368784e-2
GO:0008631 induction of apoptosis by oxidative stress 2.370967e-2
GO:0006107 oxaloacetate metabolic process 2.409298e-2
GO:0060012 synaptic transmission, glycinergic 2.428851e-2
GO:0030423 targeting of mRNA for destruction involved in RNA interference 2.428851e-2
GO:0042789 mRNA transcription from RNA polymerase II promoter 2.428851e-2
GO:0006268 DNA unwinding involved in replication 2.439225e-2
GO:0016072 rRNA metabolic process 2.450610e-2
GO:0043508 negative regulation of JUN kinase activity 2.492515e-2
GO:0090311 regulation of protein deacetylation 2.495458e-2
GO:0071205 protein localization to juxtaparanode region of axon 2.549773e-2
GO:0044091 membrane biogenesis 2.549773e-2
GO:0014034 neural crest cell fate commitment 2.549773e-2
GO:0033148 positive regulation of estrogen receptor signaling pathway 2.574245e-2
GO:0016540 protein autoprocessing 2.574245e-2
GO:0043170 macromolecule metabolic process 2.600478e-2
GO:0061136 regulation of proteasomal protein catabolic process 2.628461e-2
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 2.629445e-2
GO:0046128 purine ribonucleoside metabolic process 2.637675e-2
GO:0046364 monosaccharide biosynthetic process 2.650423e-2
GO:0021796 cerebral cortex regionalization 2.663302e-2
GO:0008542 visual learning 2.681053e-2
GO:0006783 heme biosynthetic process 2.685378e-2
GO:0031508 centromeric heterochromatin formation 2.691645e-2
GO:0045345 positive regulation of MHC class I biosynthetic process 2.691645e-2
GO:0006669 sphinganine-1-phosphate biosynthetic process 2.691645e-2
GO:0043923 positive regulation by host of viral transcription 2.705772e-2
GO:0090344 negative regulation of cell aging 2.750655e-2
GO:0006678 glucosylceramide metabolic process 2.750655e-2
GO:0070593 dendrite self-avoidance 2.754132e-2
GO:0032530 regulation of microvillus organization 2.754132e-2