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Novel motif:48

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name:motif48_CANTCG

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0071673 positive regulation of smooth muscle cell chemotaxis 2.036338e-10
GO:0016570 histone modification 2.655230e-10
GO:0016569 covalent chromatin modification 3.669223e-10
GO:0006348 chromatin silencing at telomere 6.324859e-9
GO:0051299 centrosome separation 6.940516e-9
GO:0071671 regulation of smooth muscle cell chemotaxis 8.130447e-9
GO:0001757 somite specification 1.958976e-8
GO:0060764 cell-cell signaling involved in mammary gland development 3.267861e-8
GO:0033523 histone H2B ubiquitination 9.826067e-8
GO:0060999 positive regulation of dendritic spine development 1.428422e-7
GO:0007549 dosage compensation 2.096005e-7
GO:0006281 DNA repair 3.288894e-7
GO:0035026 leading edge cell differentiation 5.253486e-7
GO:0032060 bleb assembly 5.853792e-7
GO:2000615 regulation of histone H3-K9 acetylation 7.317641e-7
GO:0060430 lung saccule development 7.798340e-7
GO:0034227 tRNA thio-modification 8.347033e-7
GO:0002098 tRNA wobble uridine modification 8.347033e-7
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 1.278172e-6
GO:0060435 bronchiole development 1.521001e-6
GO:0009048 dosage compensation, by inactivation of X chromosome 1.738219e-6
GO:0000416 positive regulation of histone H3-K36 methylation 1.738219e-6
GO:0060482 lobar bronchus development 2.016668e-6
GO:0042696 menarche 3.011241e-6
GO:0045820 negative regulation of glycolysis 3.205810e-6
GO:0070584 mitochondrion morphogenesis 3.475668e-6
GO:0090399 replicative senescence 3.519074e-6
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 4.551229e-6
GO:0042538 hyperosmotic salinity response 4.978622e-6
GO:0051457 maintenance of protein location in nucleus 5.154460e-6
GO:0021759 globus pallidus development 5.371169e-6
GO:0046950 cellular ketone body metabolic process 5.513438e-6
GO:0032472 Golgi calcium ion transport 5.523275e-6
GO:0032468 Golgi calcium ion homeostasis 5.523275e-6
GO:0030026 cellular manganese ion homeostasis 5.523275e-6
GO:0060534 trachea cartilage development 6.749888e-6
GO:0006302 double-strand break repair 8.310254e-6
GO:2001037 positive regulation of tongue muscle cell differentiation 8.408498e-6
GO:0060982 coronary artery morphogenesis 8.408498e-6
GO:0097152 mesenchymal cell apoptosis 8.408498e-6
GO:0051589 negative regulation of neurotransmitter transport 9.065883e-6
GO:0046602 regulation of mitotic centrosome separation 9.270336e-6
GO:0001675 acrosome assembly 9.270433e-6
GO:0060480 lung goblet cell differentiation 1.007628e-5
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1.016176e-5
GO:0035356 cellular triglyceride homeostasis 1.059083e-5
GO:0051154 negative regulation of striated muscle cell differentiation 1.157353e-5
GO:0043467 regulation of generation of precursor metabolites and energy 1.499124e-5
GO:0060042 retina morphogenesis in camera-type eye 1.691462e-5
GO:0006310 DNA recombination 1.840355e-5
GO:0007379 segment specification 1.919937e-5
GO:2000620 positive regulation of histone H4-K16 acetylation 2.168895e-5
GO:2000617 positive regulation of histone H3-K9 acetylation 2.168895e-5
GO:0070512 positive regulation of histone H4-K20 methylation 2.168895e-5
GO:0048842 positive regulation of axon extension involved in axon guidance 2.188447e-5
GO:0070842 aggresome assembly 2.245845e-5
GO:0018192 enzyme active site formation via L-cysteine persulfide 2.334960e-5
GO:0006482 protein demethylation 2.667085e-5
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 2.703481e-5
GO:0010225 response to UV-C 2.823308e-5
GO:0022412 cellular process involved in reproduction in multicellular organism 3.054249e-5
GO:0060535 trachea cartilage morphogenesis 3.163611e-5
GO:0031297 replication fork processing 3.234890e-5
GO:0021892 cerebral cortex GABAergic interneuron differentiation 3.238991e-5
GO:0016574 histone ubiquitination 3.360570e-5
GO:0016568 chromatin modification 3.368124e-5
GO:0051898 negative regulation of protein kinase B signaling cascade 3.999040e-5
GO:0010890 positive regulation of sequestering of triglyceride 4.181994e-5
GO:0002016 regulation of blood volume by renin-angiotensin 4.382617e-5
GO:0051571 positive regulation of histone H3-K4 methylation 4.888202e-5
GO:0040032 post-embryonic body morphogenesis 4.906675e-5
GO:0060486 Clara cell differentiation 5.268947e-5
GO:0048664 neuron fate determination 5.268947e-5
GO:0060023 soft palate development 5.486734e-5
GO:0035269 protein O-linked mannosylation 5.731060e-5
GO:0006400 tRNA modification 5.731241e-5
GO:0021783 preganglionic parasympathetic nervous system development 5.777760e-5
GO:0060574 intestinal epithelial cell maturation 6.249406e-5
GO:0048561 establishment of organ orientation 6.378266e-5
GO:0046605 regulation of centrosome cycle 7.822619e-5
GO:0046599 regulation of centriole replication 7.932251e-5
GO:0060510 Type II pneumocyte differentiation 9.166467e-5
GO:0060017 parathyroid gland development 9.201402e-5
GO:0035928 rRNA import into mitochondrion 9.242449e-5
GO:2000466 negative regulation of glycogen (starch) synthase activity 1.019570e-4
GO:0042447 hormone catabolic process 1.049875e-4
GO:0000724 double-strand break repair via homologous recombination 1.119337e-4
GO:0000725 recombinational repair 1.121114e-4
GO:0051983 regulation of chromosome segregation 1.315434e-4
GO:0010830 regulation of myotube differentiation 1.335971e-4
GO:0060816 random inactivation of X chromosome 1.381217e-4
GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly 1.492270e-4
GO:0018026 peptidyl-lysine monomethylation 1.546752e-4
GO:0006288 base-excision repair, DNA ligation 1.616130e-4
GO:0001302 replicative cell aging 1.620152e-4
GO:0090346 cellular organofluorine metabolic process 1.726128e-4
GO:0046210 nitric oxide catabolic process 1.726128e-4
GO:0043602 nitrate catabolic process 1.726128e-4
GO:0045685 regulation of glial cell differentiation 1.752341e-4
GO:0048704 embryonic skeletal system morphogenesis 1.850137e-4
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1.877556e-4
GO:0048486 parasympathetic nervous system development 1.927819e-4
GO:0060876 semicircular canal formation 1.951779e-4
GO:0009648 photoperiodism 1.957521e-4
GO:0060059 embryonic retina morphogenesis in camera-type eye 1.996762e-4
GO:0010390 histone monoubiquitination 1.997782e-4
GO:0051365 cellular response to potassium ion starvation 2.041602e-4
GO:0051645 Golgi localization 2.041602e-4
GO:0016575 histone deacetylation 2.062493e-4
GO:0016254 preassembly of GPI anchor in ER membrane 2.095981e-4
GO:0060465 pharynx development 2.107803e-4
GO:0006013 mannose metabolic process 2.161502e-4
GO:0015891 siderophore transport 2.223391e-4
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 2.281983e-4
GO:0061013 regulation of mRNA catabolic process 2.287995e-4
GO:0000414 regulation of histone H3-K36 methylation 2.349214e-4
GO:0015820 leucine transport 2.548092e-4
GO:0045607 regulation of auditory receptor cell differentiation 2.561686e-4
GO:0034389 lipid particle organization 2.572625e-4
GO:0048713 regulation of oligodendrocyte differentiation 2.612549e-4
GO:0048663 neuron fate commitment 2.788239e-4
GO:0051181 cofactor transport 3.085856e-4
GO:0021675 nerve development 3.098300e-4
GO:0002002 regulation of angiotensin levels in blood 3.130984e-4
GO:0046951 ketone body biosynthetic process 3.158820e-4
GO:0030421 defecation 3.176553e-4
GO:0018022 peptidyl-lysine methylation 3.179647e-4
GO:0021569 rhombomere 3 development 3.204431e-4
GO:0005981 regulation of glycogen catabolic process 3.211246e-4
GO:0050847 progesterone receptor signaling pathway 3.211246e-4
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 3.231510e-4
GO:0015742 alpha-ketoglutarate transport 3.427632e-4
GO:0071503 response to heparin 3.472405e-4
GO:0000413 protein peptidyl-prolyl isomerization 3.496093e-4
GO:0046952 ketone body catabolic process 3.588084e-4
GO:0060850 regulation of transcription involved in cell fate commitment 3.601496e-4
GO:0046293 formaldehyde biosynthetic process 3.617633e-4
GO:0045608 negative regulation of auditory receptor cell differentiation 3.624762e-4
GO:0071584 negative regulation of zinc ion import 3.819796e-4
GO:0090281 negative regulation of calcium ion import 3.819796e-4
GO:0007100 mitotic centrosome separation 3.819796e-4
GO:0045819 positive regulation of glycogen catabolic process 3.861654e-4
GO:0051955 regulation of amino acid transport 3.869092e-4
GO:0010719 negative regulation of epithelial to mesenchymal transition 3.946338e-4
GO:0010986 positive regulation of lipoprotein particle clearance 3.964890e-4
GO:0060347 heart trabecula formation 4.019999e-4
GO:0046600 negative regulation of centriole replication 4.042720e-4
GO:0060356 leucine import 4.165180e-4
GO:0032836 glomerular basement membrane development 4.251438e-4
GO:0007506 gonadal mesoderm development 4.545142e-4
GO:0046939 nucleotide phosphorylation 4.558982e-4
GO:0043457 regulation of cellular respiration 4.678169e-4
GO:0006844 acyl carnitine transport 4.783368e-4
GO:0006308 DNA catabolic process 4.784677e-4
GO:0007344 pronuclear fusion 4.993961e-4
GO:0060433 bronchus development 5.167963e-4
GO:0018208 peptidyl-proline modification 5.451135e-4
GO:0016577 histone demethylation 5.499334e-4
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 5.568147e-4
GO:0070988 demethylation 5.570499e-4
GO:0048752 semicircular canal morphogenesis 5.594658e-4
GO:2001014 regulation of skeletal muscle cell differentiation 5.712673e-4
GO:0043471 regulation of cellular carbohydrate catabolic process 5.865529e-4
GO:0021895 cerebral cortex neuron differentiation 6.205618e-4
GO:0010889 regulation of sequestering of triglyceride 6.360576e-4
GO:0061014 positive regulation of mRNA catabolic process 6.531000e-4
GO:0045655 regulation of monocyte differentiation 6.544051e-4
GO:0060487 lung epithelial cell differentiation 6.634292e-4
GO:0007092 activation of mitotic anaphase-promoting complex activity 6.886609e-4
GO:0031658 negative regulation of cyclin-dependent protein kinase activity involved in G1/S 6.886609e-4
GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus 6.886609e-4
GO:0006044 N-acetylglucosamine metabolic process 7.059444e-4
GO:0071338 positive regulation of hair follicle cell proliferation 7.077078e-4
GO:0021819 layer formation in cerebral cortex 7.077078e-4
GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation 7.119820e-4
GO:0008292 acetylcholine biosynthetic process 7.611654e-4
GO:0021602 cranial nerve morphogenesis 7.634565e-4
GO:0071529 cementum mineralization 8.014088e-4
GO:0018206 peptidyl-methionine modification 8.014088e-4
GO:0010948 negative regulation of cell cycle process 8.023547e-4
GO:0061384 heart trabecular morphogenesis 8.096310e-4
GO:0051569 regulation of histone H3-K4 methylation 8.133423e-4
GO:0051612 negative regulation of serotonin uptake 8.156165e-4
GO:0034968 histone lysine methylation 8.270196e-4
GO:0009886 post-embryonic morphogenesis 8.378160e-4
GO:0010832 negative regulation of myotube differentiation 8.577805e-4
GO:0007522 visceral muscle development 8.904287e-4
GO:0046469 platelet activating factor metabolic process 9.004104e-4
GO:0031573 intra-S DNA damage checkpoint 9.204132e-4
GO:0006325 chromatin organization 9.250747e-4
GO:0006513 protein monoubiquitination 9.456788e-4
GO:0006047 UDP-N-acetylglucosamine metabolic process 9.540061e-4
GO:0007141 male meiosis I 9.540061e-4
GO:0002036 regulation of L-glutamate transport 9.798030e-4
GO:0051276 chromosome organization 9.992279e-4
GO:0007569 cell aging 1.017547e-3
GO:0045657 positive regulation of monocyte differentiation 1.025199e-3
GO:0043414 macromolecule methylation 1.063121e-3
GO:2001054 negative regulation of mesenchymal cell apoptosis 1.128233e-3
GO:0034959 endothelin maturation 1.183278e-3
GO:0010814 substance P catabolic process 1.183278e-3
GO:0010816 calcitonin catabolic process 1.183278e-3
GO:0032581 ER-dependent peroxisome organization 1.228570e-3
GO:0031576 G2/M transition checkpoint 1.277981e-3
GO:0007109 cytokinesis, completion of separation 1.291324e-3
GO:0018198 peptidyl-cysteine modification 1.304434e-3
GO:0071504 cellular response to heparin 1.304434e-3
GO:0034766 negative regulation of ion transmembrane transport 1.385377e-3
GO:0010677 negative regulation of cellular carbohydrate metabolic process 1.401601e-3
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 1.409712e-3
GO:0051029 rRNA transport 1.411023e-3
GO:0034551 mitochondrial respiratory chain complex III assembly 1.411128e-3
GO:0072595 maintenance of protein localization to organelle 1.433021e-3
GO:0045210 FasL biosynthetic process 1.531406e-3
GO:0097039 protein linear polyubiquitination 1.531406e-3
GO:0000966 RNA 5'-end processing 1.538746e-3
GO:0090075 relaxation of muscle 1.540375e-3
GO:0000072 M phase specific microtubule process 1.620757e-3
GO:0021517 ventral spinal cord development 1.790355e-3
GO:0060977 coronary vasculature morphogenesis 1.848256e-3
GO:0051532 regulation of NFAT protein import into nucleus 1.848375e-3
GO:0007386 compartment pattern specification 1.848375e-3
GO:0006501 C-terminal protein lipidation 1.850427e-3
GO:0043922 negative regulation by host of viral transcription 1.850478e-3
GO:0032007 negative regulation of TOR signaling cascade 1.897099e-3
GO:0007296 vitellogenesis 1.897099e-3
GO:0007097 nuclear migration 1.905079e-3
GO:0072126 positive regulation of glomerular mesangial cell proliferation 1.914101e-3
GO:0071506 cellular response to mycophenolic acid 1.914101e-3
GO:0090239 regulation of histone H4 acetylation 1.961299e-3
GO:0043153 entrainment of circadian clock by photoperiod 1.983169e-3
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.990517e-3
GO:0051660 establishment of centrosome localization 2.031979e-3
GO:0021540 corpus callosum morphogenesis 2.031979e-3
GO:0060060 post-embryonic retina morphogenesis in camera-type eye 2.047982e-3
GO:0019358 nicotinate nucleotide salvage 2.142526e-3
GO:0006479 protein methylation 2.201026e-3
GO:0097150 neuronal stem cell maintenance 2.224056e-3
GO:0001921 positive regulation of receptor recycling 2.224056e-3
GO:0060021 palate development 2.250199e-3
GO:0090102 cochlea development 2.287703e-3
GO:0003148 outflow tract septum morphogenesis 2.295519e-3
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion 2.300360e-3
GO:0035461 vitamin transmembrane transport 2.303205e-3
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 2.303205e-3
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 2.303205e-3
GO:0021798 forebrain dorsal/ventral pattern formation 2.322574e-3
GO:0006476 protein deacetylation 2.348175e-3
GO:0090307 spindle assembly involved in mitosis 2.357836e-3
GO:0034699 response to luteinizing hormone stimulus 2.361415e-3
GO:0035166 post-embryonic hemopoiesis 2.401186e-3
GO:0000718 nucleotide-excision repair, DNA damage removal 2.424680e-3
GO:0046292 formaldehyde metabolic process 2.472692e-3
GO:0060177 regulation of angiotensin metabolic process 2.509982e-3
GO:0060318 definitive erythrocyte differentiation 2.569775e-3
GO:0044330 canonical Wnt receptor signaling pathway involved in positive regulation of wound healing 2.600688e-3
GO:0044328 canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration 2.600688e-3
GO:0044329 canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion 2.600688e-3
GO:0034645 cellular macromolecule biosynthetic process 2.602524e-3
GO:0021599 abducens nerve formation 2.611802e-3
GO:0019428 allantoin biosynthetic process 2.611802e-3
GO:0007634 optokinetic behavior 2.611802e-3
GO:0070625 zymogen granule exocytosis 2.631235e-3
GO:0035601 protein deacylation 2.635931e-3
GO:0001990 regulation of systemic arterial blood pressure by hormone 2.660422e-3
GO:0006094 gluconeogenesis 2.711898e-3
GO:0001832 blastocyst growth 2.719824e-3
GO:0006048 UDP-N-acetylglucosamine biosynthetic process 2.842050e-3
GO:0002678 positive regulation of chronic inflammatory response 2.874276e-3
GO:0030953 astral microtubule organization 2.877569e-3
GO:0070874 negative regulation of glycogen metabolic process 2.997766e-3
GO:0033683 nucleotide-excision repair, DNA incision 2.997766e-3
GO:0034447 very-low-density lipoprotein particle clearance 3.077069e-3
GO:0014053 negative regulation of gamma-aminobutyric acid secretion 3.143908e-3
GO:0060428 lung epithelium development 3.166809e-3
GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 3.282959e-3
GO:0021644 vagus nerve morphogenesis 3.387369e-3
GO:0043461 proton-transporting ATP synthase complex assembly 3.392669e-3
GO:0019348 dolichol metabolic process 3.392669e-3
GO:0060351 cartilage development involved in endochondral bone morphogenesis 3.405545e-3
GO:0060576 intestinal epithelial cell development 3.456690e-3
GO:0051103 DNA ligation involved in DNA repair 3.456690e-3
GO:0002676 regulation of chronic inflammatory response 3.499820e-3
GO:0034393 positive regulation of smooth muscle cell apoptosis 3.544813e-3
GO:0090304 nucleic acid metabolic process 3.645748e-3
GO:0031572 G2/M transition DNA damage checkpoint 3.676483e-3
GO:0007181 transforming growth factor beta receptor complex assembly 3.689890e-3
GO:0060872 semicircular canal development 3.693500e-3
GO:0003420 regulation of growth plate cartilage chondrocyte proliferation 3.718281e-3
GO:0002689 negative regulation of leukocyte chemotaxis 3.720375e-3
GO:0015788 UDP-N-acetylglucosamine transport 3.803271e-3
GO:0007140 male meiosis 3.803488e-3
GO:0090398 cellular senescence 3.815684e-3
GO:0060282 positive regulation of oocyte development 3.825235e-3
GO:0055119 relaxation of cardiac muscle 3.933204e-3
GO:0007253 cytoplasmic sequestering of NF-kappaB 3.997508e-3
GO:0007063 regulation of sister chromatid cohesion 3.997508e-3
GO:0009225 nucleotide-sugar metabolic process 4.026949e-3
GO:0021681 cerebellar granular layer development 4.089446e-3
GO:0006335 DNA replication-dependent nucleosome assembly 4.100243e-3
GO:0000183 chromatin silencing at rDNA 4.179965e-3
GO:0060087 relaxation of vascular smooth muscle 4.225123e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 4.248259e-3
GO:0061003 positive regulation of dendritic spine morphogenesis 4.248259e-3
GO:0051790 short-chain fatty acid biosynthetic process 4.322274e-3
GO:0006974 response to DNA damage stimulus 4.399804e-3
GO:0018095 protein polyglutamylation 4.418298e-3
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 4.464678e-3
GO:0071313 cellular response to caffeine 4.464678e-3
GO:0010983 positive regulation of high-density lipoprotein particle clearance 4.464678e-3
GO:0035545 determination of left/right asymmetry in nervous system 4.464678e-3
GO:0021612 facial nerve structural organization 4.523010e-3
GO:0090136 epithelial cell-cell adhesion 4.553361e-3
GO:0070384 Harderian gland development 4.683849e-3
GO:0034498 early endosome to Golgi transport 4.683849e-3
GO:0031914 negative regulation of synaptic plasticity 4.683849e-3
GO:0072331 signal transduction by p53 class mediator 4.700916e-3
GO:0032897 negative regulation of viral transcription 4.749976e-3
GO:0060479 lung cell differentiation 4.751956e-3
GO:0050883 musculoskeletal movement, spinal reflex action 4.916176e-3
GO:0032938 negative regulation of translation in response to oxidative stress 4.916176e-3
GO:0043171 peptide catabolic process 4.958345e-3
GO:0015884 folic acid transport 4.958345e-3
GO:0021528 commissural neuron differentiation in spinal cord 4.962325e-3
GO:0070159 mitochondrial threonyl-tRNA aminoacylation 4.962325e-3
GO:0006051 N-acetylmannosamine metabolic process 4.962325e-3
GO:0021545 cranial nerve development 5.012697e-3
GO:0018410 C-terminal protein amino acid modification 5.085850e-3
GO:0007612 learning 5.096670e-3
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 5.142651e-3
GO:0007207 activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway 5.312024e-3
GO:0030828 positive regulation of cGMP biosynthetic process 5.312024e-3
GO:0051534 negative regulation of NFAT protein import into nucleus 5.505111e-3
GO:0070562 regulation of vitamin D receptor signaling pathway 5.517328e-3
GO:0021570 rhombomere 4 development 5.517328e-3
GO:0044260 cellular macromolecule metabolic process 5.603251e-3
GO:0006548 histidine catabolic process 5.624337e-3
GO:0009059 macromolecule biosynthetic process 5.654026e-3
GO:0051647 nucleus localization 5.656707e-3
GO:0014037 Schwann cell differentiation 5.722292e-3
GO:0014013 regulation of gliogenesis 5.723296e-3
GO:0007020 microtubule nucleation 5.727779e-3
GO:0000959 mitochondrial RNA metabolic process 5.727779e-3
GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly 5.761478e-3
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 5.772478e-3
GO:0060575 intestinal epithelial cell differentiation 5.783830e-3
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 5.808334e-3
GO:0071585 detoxification of cadmium ion 5.840069e-3
GO:0072668 tubulin complex biogenesis 5.848614e-3
GO:0042772 DNA damage response, signal transduction resulting in transcription 5.956817e-3
GO:0031365 N-terminal protein amino acid modification 5.972818e-3
GO:0055118 negative regulation of cardiac muscle contraction 6.174943e-3
GO:0048706 embryonic skeletal system development 6.179845e-3
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 6.246013e-3
GO:0045719 negative regulation of glycogen biosynthetic process 6.277282e-3
GO:0018027 peptidyl-lysine dimethylation 6.303838e-3
GO:0016571 histone methylation 6.365720e-3
GO:0000075 cell cycle checkpoint 6.460044e-3
GO:0008033 tRNA processing 6.460984e-3
GO:0060045 positive regulation of cardiac muscle cell proliferation 6.480297e-3
GO:0002369 T cell cytokine production 6.510659e-3
GO:0001963 synaptic transmission, dopaminergic 6.555881e-3
GO:0071816 tail-anchored membrane protein insertion into ER membrane 6.833424e-3
GO:0010815 bradykinin catabolic process 6.833424e-3
GO:0045687 positive regulation of glial cell differentiation 6.842329e-3
GO:0048714 positive regulation of oligodendrocyte differentiation 6.952662e-3
GO:0009650 UV protection 7.069248e-3
GO:0071934 thiamine transmembrane transport 7.159067e-3
GO:0009159 deoxyribonucleoside monophosphate catabolic process 7.159067e-3
GO:0035445 borate transmembrane transport 7.159067e-3
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system 7.159067e-3
GO:0016598 protein arginylation 7.159067e-3
GO:0033233 regulation of protein sumoylation 7.166808e-3
GO:0018105 peptidyl-serine phosphorylation 7.167941e-3
GO:0000965 mitochondrial RNA 3'-end processing 7.217471e-3
GO:0000962 positive regulation of mitochondrial RNA catabolic process 7.217471e-3
GO:0000958 mitochondrial mRNA catabolic process 7.217471e-3
GO:0046358 butyrate biosynthetic process 7.281477e-3
GO:0060580 ventral spinal cord interneuron fate determination 7.281477e-3
GO:0003327 type B pancreatic cell fate commitment 7.281477e-3
GO:0071156 regulation of cell cycle arrest 7.349508e-3
GO:0051488 activation of anaphase-promoting complex activity 7.442697e-3
GO:0006449 regulation of translational termination 7.450039e-3
GO:0017004 cytochrome complex assembly 7.555361e-3
GO:0002367 cytokine production involved in immune response 7.724431e-3
GO:0055009 atrial cardiac muscle tissue morphogenesis 7.728295e-3
GO:0051988 regulation of attachment of spindle microtubules to kinetochore 7.803288e-3
GO:0009451 RNA modification 7.817443e-3
GO:0051584 regulation of dopamine uptake 7.861652e-3
GO:0021520 spinal cord motor neuron cell fate specification 7.863997e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 7.930340e-3
GO:0032020 ISG15-protein conjugation 7.992885e-3
GO:0014052 regulation of gamma-aminobutyric acid secretion 7.992885e-3
GO:0007538 primary sex determination 8.094003e-3
GO:0061072 iris morphogenesis 8.163653e-3
GO:0060596 mammary placode formation 8.185352e-3
GO:0009147 pyrimidine nucleoside triphosphate metabolic process 8.263687e-3
GO:0060998 regulation of dendritic spine development 8.428319e-3
GO:0016486 peptide hormone processing 8.488818e-3
GO:0042228 interleukin-8 biosynthetic process 8.513521e-3
GO:0035621 ER to Golgi ceramide transport 8.513521e-3
GO:0043316 cytotoxic T cell degranulation 8.609588e-3
GO:0001830 trophectodermal cell fate commitment 8.609588e-3
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 8.614396e-3
GO:0035019 somatic stem cell maintenance 8.648268e-3
GO:0046364 monosaccharide biosynthetic process 8.673294e-3
GO:0015872 dopamine transport 8.712943e-3
GO:0072109 glomerular mesangium development 8.743948e-3
GO:0006659 phosphatidylserine biosynthetic process 8.743948e-3
GO:0072110 glomerular mesangial cell proliferation 8.792856e-3
GO:0046349 amino sugar biosynthetic process 8.792856e-3
GO:0034198 cellular response to amino acid starvation 9.066486e-3
GO:0006826 iron ion transport 9.108553e-3
GO:0031860 telomeric 3' overhang formation 9.173873e-3
GO:0043456 regulation of pentose-phosphate shunt 9.173873e-3
GO:0016078 tRNA catabolic process 9.173873e-3
GO:0001682 tRNA 5'-leader removal 9.173873e-3
GO:0006002 fructose 6-phosphate metabolic process 9.326610e-3
GO:0035025 positive regulation of Rho protein signal transduction 9.378578e-3
GO:0048562 embryonic organ morphogenesis 9.414130e-3
GO:0043441 acetoacetic acid biosynthetic process 9.450104e-3
GO:0070846 Hsp90 deacetylation 9.525683e-3
GO:2000252 negative regulation of feeding behavior 9.525683e-3
GO:0090042 tubulin deacetylation 9.525683e-3
GO:0006272 leading strand elongation 9.525683e-3
GO:0016095 polyprenol catabolic process 9.525683e-3
GO:0018916 nitrobenzene metabolic process 9.525683e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 9.630690e-3
GO:0014014 negative regulation of gliogenesis 9.734245e-3
GO:0048073 regulation of eye pigmentation 9.839599e-3
GO:0009440 cyanate catabolic process 9.909469e-3
GO:0009051 pentose-phosphate shunt, oxidative branch 9.909469e-3
GO:0045814 negative regulation of gene expression, epigenetic 9.947696e-3
GO:0003407 neural retina development 1.012908e-2
GO:0070375 BMK cascade 1.033317e-2
GO:0006344 maintenance of chromatin silencing 1.033317e-2
GO:0055014 atrial cardiac muscle cell development 1.033317e-2
GO:0022027 interkinetic nuclear migration 1.036092e-2
GO:0021546 rhombomere development 1.055372e-2
GO:0033861 negative regulation of NAD(P)H oxidase activity 1.089057e-2
GO:0021903 rostrocaudal neural tube patterning 1.098943e-2
GO:0016048 detection of temperature stimulus 1.117066e-2
GO:0072393 microtubule anchoring at microtubule organizing center 1.142843e-2
GO:0016584 nucleosome positioning 1.142843e-2
GO:0006269 DNA replication, synthesis of RNA primer 1.188818e-2
GO:0006261 DNA-dependent DNA replication 1.190562e-2
GO:0043585 nose morphogenesis 1.194976e-2
GO:0060976 coronary vasculature development 1.221903e-2
GO:0090342 regulation of cell aging 1.224726e-2
GO:0003360 brainstem development 1.225338e-2
GO:0022601 menstrual cycle phase 1.231427e-2
GO:0060349 bone morphogenesis 1.236731e-2
GO:0044027 hypermethylation of CpG island 1.242013e-2
GO:0060152 microtubule-based peroxisome localization 1.242924e-2
GO:0070873 regulation of glycogen metabolic process 1.258519e-2
GO:0030330 DNA damage response, signal transduction by p53 class mediator 1.258610e-2
GO:0045175 basal protein localization 1.283609e-2
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 1.284221e-2
GO:0035417 negative regulation of mitotic prometaphase 1.288920e-2
GO:0090234 regulation of kinetochore assembly 1.295005e-2
GO:0090169 regulation of spindle assembly 1.295005e-2
GO:0060839 endothelial cell fate commitment 1.321874e-2
GO:0034501 protein localization to kinetochore 1.336710e-2
GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process 1.336710e-2
GO:2000772 regulation of cellular senescence 1.350976e-2
GO:0032205 negative regulation of telomere maintenance 1.354900e-2
GO:0021522 spinal cord motor neuron differentiation 1.355258e-2
GO:0031627 telomeric loop formation 1.357214e-2
GO:0060304 regulation of phosphatidylinositol dephosphorylation 1.357214e-2
GO:0031119 tRNA pseudouridine synthesis 1.357214e-2
GO:0030042 actin filament depolymerization 1.357214e-2
GO:0042274 ribosomal small subunit biogenesis 1.362140e-2
GO:0001553 luteinization 1.374567e-2
GO:0045168 cell-cell signaling involved in cell fate commitment 1.378342e-2
GO:0040030 regulation of molecular function, epigenetic 1.386616e-2
GO:2000251 positive regulation of actin cytoskeleton reorganization 1.386616e-2
GO:0006828 manganese ion transport 1.414549e-2
GO:0050872 white fat cell differentiation 1.425554e-2
GO:0031570 DNA integrity checkpoint 1.431839e-2
GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1.467370e-2
GO:0042136 neurotransmitter biosynthetic process 1.468783e-2
GO:0018205 peptidyl-lysine modification 1.474798e-2
GO:0051972 regulation of telomerase activity 1.499489e-2
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.515124e-2
GO:0050775 positive regulation of dendrite morphogenesis 1.527237e-2
GO:0042254 ribosome biogenesis 1.532753e-2
GO:0055021 regulation of cardiac muscle tissue growth 1.535825e-2
GO:0009651 response to salt stress 1.546052e-2
GO:0006413 translational initiation 1.548273e-2
GO:0003310 pancreatic A cell differentiation 1.554475e-2
GO:0072061 inner medullary collecting duct development 1.562448e-2
GO:0072060 outer medullary collecting duct development 1.562448e-2
GO:0000492 box C/D snoRNP assembly 1.562448e-2
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 1.562448e-2
GO:0043653 mitochondrial fragmentation involved in apoptosis 1.567290e-2
GO:0000422 mitochondrion degradation 1.567290e-2
GO:0090219 negative regulation of lipid kinase activity 1.585169e-2
GO:0045842 positive regulation of mitotic metaphase/anaphase transition 1.588758e-2
GO:0015827 tryptophan transport 1.588758e-2
GO:0051973 positive regulation of telomerase activity 1.605713e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0031167 rRNA methylation 3.661943e-13
GO:0000154 rRNA modification 1.950983e-11
GO:0022402 cell cycle process 3.733648e-9
GO:0006396 RNA processing 1.114421e-8
GO:0016072 rRNA metabolic process 1.460524e-8
GO:0042254 ribosome biogenesis 2.154605e-8
GO:0006364 rRNA processing 7.512648e-8
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 2.192692e-7
GO:0022403 cell cycle phase 4.350337e-7
GO:0050685 positive regulation of mRNA processing 7.934968e-7
GO:0050668 positive regulation of homocysteine metabolic process 8.050108e-7
GO:0045963 negative regulation of dopamine metabolic process 8.050108e-7
GO:0071843 cellular component biogenesis at cellular level 1.306779e-6
GO:0022613 ribonucleoprotein complex biogenesis 1.469729e-6
GO:0030902 hindbrain development 1.484355e-6
GO:0019255 glucose 1-phosphate metabolic process 1.936321e-6
GO:0019047 provirus integration 1.967026e-6
GO:0007049 cell cycle 6.174563e-6
GO:0000917 barrier septum formation 6.501464e-6
GO:0032922 circadian regulation of gene expression 6.662115e-6
GO:0000239 pachytene 7.061628e-6
GO:0000279 M phase 1.154355e-5
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1.192954e-5
GO:0015761 mannose transport 1.362925e-5
GO:0031442 positive regulation of mRNA 3'-end processing 1.539904e-5
GO:0035282 segmentation 2.013668e-5
GO:0040029 regulation of gene expression, epigenetic 2.231253e-5
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2.250940e-5
GO:0061014 positive regulation of mRNA catabolic process 2.295242e-5
GO:0006657 CDP-choline pathway 3.110970e-5
GO:0034446 substrate adhesion-dependent cell spreading 3.157415e-5
GO:0032446 protein modification by small protein conjugation 4.009260e-5
GO:0034470 ncRNA processing 4.444451e-5
GO:0016567 protein ubiquitination 4.483084e-5
GO:0016331 morphogenesis of embryonic epithelium 4.991794e-5
GO:0021549 cerebellum development 5.291327e-5
GO:0090224 regulation of spindle organization 5.687580e-5
GO:0051176 positive regulation of sulfur metabolic process 6.007567e-5
GO:0061053 somite development 6.838208e-5
GO:0042147 retrograde transport, endosome to Golgi 7.372936e-5
GO:0006306 DNA methylation 7.824205e-5
GO:0009138 pyrimidine nucleoside diphosphate metabolic process 7.856320e-5
GO:0007099 centriole replication 7.856320e-5
GO:0070165 positive regulation of adiponectin secretion 8.399503e-5
GO:0045362 positive regulation of interleukin-1 biosynthetic process 8.399503e-5
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 8.399503e-5
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 8.399503e-5
GO:0032707 negative regulation of interleukin-23 production 8.399503e-5
GO:0033031 positive regulation of neutrophil apoptosis 8.399503e-5
GO:0033617 mitochondrial respiratory chain complex IV assembly 8.399503e-5
GO:0051586 positive regulation of dopamine uptake 8.466149e-5
GO:0061013 regulation of mRNA catabolic process 8.494301e-5
GO:0010870 positive regulation of receptor biosynthetic process 1.040454e-4
GO:0061386 closure of optic fissure 1.069829e-4
GO:0035332 positive regulation of hippo signaling cascade 1.069829e-4
GO:0035148 tube formation 1.234254e-4
GO:0048704 embryonic skeletal system morphogenesis 1.256242e-4
GO:0001841 neural tube formation 1.368940e-4
GO:0072298 regulation of metanephric glomerulus development 1.383045e-4
GO:0001510 RNA methylation 1.429574e-4
GO:0032259 methylation 1.454355e-4
GO:0001555 oocyte growth 1.458731e-4
GO:0006261 DNA-dependent DNA replication 1.550924e-4
GO:0006139 nucleobase-containing compound metabolic process 1.567049e-4
GO:0051225 spindle assembly 1.647325e-4
GO:0090304 nucleic acid metabolic process 1.700409e-4
GO:0031440 regulation of mRNA 3'-end processing 1.706016e-4
GO:0045749 negative regulation of S phase of mitotic cell cycle 1.758944e-4
GO:0001838 embryonic epithelial tube formation 1.765151e-4
GO:0022037 metencephalon development 1.849580e-4
GO:0090286 cytoskeletal anchoring at nuclear membrane 1.920600e-4
GO:0001756 somitogenesis 1.985356e-4
GO:0000726 non-recombinational repair 2.080747e-4
GO:0043414 macromolecule methylation 2.109238e-4
GO:0060022 hard palate development 2.111993e-4
GO:0009952 anterior/posterior pattern specification 2.177835e-4
GO:0048706 embryonic skeletal system development 2.233043e-4
GO:0045930 negative regulation of mitotic cell cycle 2.239902e-4
GO:0032418 lysosome localization 2.281525e-4
GO:0034660 ncRNA metabolic process 2.431991e-4
GO:0072527 pyrimidine-containing compound metabolic process 2.518803e-4
GO:0090192 regulation of glomerulus development 2.662706e-4
GO:0032790 ribosome disassembly 2.718188e-4
GO:0018242 protein O-linked glycosylation via serine 2.942083e-4
GO:0018243 protein O-linked glycosylation via threonine 2.942083e-4
GO:0045666 positive regulation of neuron differentiation 2.954538e-4
GO:0003002 regionalization 3.000390e-4
GO:0072175 epithelial tube formation 3.072082e-4
GO:0006493 protein O-linked glycosylation 3.160008e-4
GO:0048705 skeletal system morphogenesis 3.174013e-4
GO:0007128 meiotic prophase I 3.200397e-4
GO:0060023 soft palate development 3.206593e-4
GO:2000678 negative regulation of transcription regulatory region DNA binding 3.206593e-4
GO:0051926 negative regulation of calcium ion transport 3.220664e-4
GO:0038007 netrin-activated signaling pathway 3.380494e-4
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 3.380494e-4
GO:0016340 calcium-dependent cell-matrix adhesion 3.448123e-4
GO:0000237 leptotene 3.661119e-4
GO:0006233 dTDP biosynthetic process 3.671890e-4
GO:0007346 regulation of mitotic cell cycle 3.713796e-4
GO:0042637 catagen 3.748060e-4
GO:0060012 synaptic transmission, glycinergic 3.777792e-4
GO:0051594 detection of glucose 3.833603e-4
GO:0043576 regulation of respiratory gaseous exchange 4.121939e-4
GO:0045764 positive regulation of cellular amino acid metabolic process 4.360914e-4
GO:0061298 retina vasculature development in camera-type eye 4.399264e-4
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 5.058557e-4
GO:0001839 neural plate morphogenesis 5.412579e-4
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 5.412579e-4
GO:0060262 negative regulation of N-terminal protein palmitoylation 5.488381e-4
GO:0001840 neural plate development 5.611959e-4
GO:0021915 neural tube development 5.689231e-4
GO:0006011 UDP-glucose metabolic process 5.959846e-4
GO:0071480 cellular response to gamma radiation 6.720399e-4
GO:0051298 centrosome duplication 6.909889e-4
GO:0043117 positive regulation of vascular permeability 6.957375e-4
GO:0050779 RNA destabilization 7.063858e-4
GO:0042420 dopamine catabolic process 7.063858e-4
GO:0042346 positive regulation of NF-kappaB import into nucleus 7.278896e-4
GO:0046605 regulation of centrosome cycle 7.402615e-4
GO:0000278 mitotic cell cycle 7.543268e-4
GO:0006713 glucocorticoid catabolic process 7.622184e-4
GO:0090316 positive regulation of intracellular protein transport 8.144112e-4
GO:0060389 pathway-restricted SMAD protein phosphorylation 8.425765e-4
GO:0010468 regulation of gene expression 8.684237e-4
GO:0046824 positive regulation of nucleocytoplasmic transport 9.034662e-4
GO:0072215 regulation of metanephros development 9.156599e-4
GO:0072300 positive regulation of metanephric glomerulus development 9.325558e-4
GO:2000648 positive regulation of stem cell proliferation 9.560206e-4
GO:0022007 convergent extension involved in neural plate elongation 9.696784e-4
GO:0018202 peptidyl-histidine modification 9.757156e-4
GO:0000255 allantoin metabolic process 9.904214e-4
GO:0051301 cell division 1.006147e-3
GO:0060562 epithelial tube morphogenesis 1.025281e-3
GO:0006303 double-strand break repair via nonhomologous end joining 1.027555e-3
GO:0032388 positive regulation of intracellular transport 1.062029e-3
GO:0051252 regulation of RNA metabolic process 1.067900e-3
GO:0090179 planar cell polarity pathway involved in neural tube closure 1.101286e-3
GO:0060174 limb bud formation 1.135011e-3
GO:0060364 frontal suture morphogenesis 1.175852e-3
GO:0048295 positive regulation of isotype switching to IgE isotypes 1.213783e-3
GO:0007098 centrosome cycle 1.221925e-3
GO:0008380 RNA splicing 1.224285e-3
GO:2001022 positive regulation of response to DNA damage stimulus 1.225056e-3
GO:0050684 regulation of mRNA processing 1.243666e-3
GO:2000112 regulation of cellular macromolecule biosynthetic process 1.244399e-3
GO:0016458 gene silencing 1.282345e-3
GO:0000910 cytokinesis 1.295075e-3
GO:2000602 regulation of interphase of mitotic cell cycle 1.313879e-3
GO:0070507 regulation of microtubule cytoskeleton organization 1.313879e-3
GO:0007059 chromosome segregation 1.319892e-3
GO:0002011 morphogenesis of an epithelial sheet 1.326709e-3
GO:0051321 meiotic cell cycle 1.376023e-3
GO:0007023 post-chaperonin tubulin folding pathway 1.433202e-3
GO:0042360 vitamin E metabolic process 1.433202e-3
GO:0042473 outer ear morphogenesis 1.478316e-3
GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process 1.505629e-3
GO:0007140 male meiosis 1.528366e-3
GO:2000976 regulation of transcription from RNA polymerase II promoter involved in detection of glucose 1.539128e-3
GO:2000971 negative regulation of detection of glucose 1.539128e-3
GO:0000433 negative regulation of transcription from RNA polymerase II promoter by glucose 1.539128e-3
GO:0007052 mitotic spindle organization 1.582983e-3
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 1.671352e-3
GO:0060563 neuroepithelial cell differentiation 1.692622e-3
GO:0060236 regulation of mitotic spindle organization 1.734954e-3
GO:0043932 ossification involved in bone remodeling 1.734954e-3
GO:0016070 RNA metabolic process 1.742802e-3
GO:0035330 regulation of hippo signaling cascade 1.754411e-3
GO:0007067 mitosis 1.758588e-3
GO:0014009 glial cell proliferation 1.786827e-3
GO:0051726 regulation of cell cycle 1.823994e-3
GO:0051496 positive regulation of stress fiber assembly 1.877036e-3
GO:0016071 mRNA metabolic process 1.894975e-3
GO:0046068 cGMP metabolic process 1.917944e-3
GO:0001832 blastocyst growth 1.945461e-3
GO:0006352 transcription initiation, DNA-dependent 1.979165e-3
GO:0090292 nuclear matrix anchoring at nuclear membrane 1.986202e-3
GO:0042996 regulation of Golgi to plasma membrane protein transport 1.986202e-3
GO:0060600 dichotomous subdivision of an epithelial terminal unit 2.050784e-3
GO:0002087 regulation of respiratory gaseous exchange by neurological system process 2.101686e-3
GO:0007090 regulation of S phase of mitotic cell cycle 2.121549e-3
GO:0032288 myelin assembly 2.220049e-3
GO:0043060 meiotic metaphase I plate congression 2.329945e-3
GO:0040023 establishment of nucleus localization 2.351725e-3
GO:0006397 mRNA processing 2.361347e-3
GO:0090307 spindle assembly involved in mitosis 2.377652e-3
GO:0090193 positive regulation of glomerulus development 2.407053e-3
GO:0070535 histone H2A K63-linked ubiquitination 2.408210e-3
GO:0071218 cellular response to misfolded protein 2.486074e-3
GO:0021998 neural plate mediolateral regionalization 2.488625e-3
GO:0048352 paraxial mesoderm structural organization 2.488625e-3
GO:0008208 C21-steroid hormone catabolic process 2.488625e-3
GO:0048477 oogenesis 2.490324e-3
GO:0070562 regulation of vitamin D receptor signaling pathway 2.498139e-3
GO:0010025 wax biosynthetic process 2.498139e-3
GO:0034764 positive regulation of transmembrane transport 2.612852e-3
GO:0006268 DNA unwinding involved in replication 2.632910e-3
GO:0000087 M phase of mitotic cell cycle 2.674598e-3
GO:0045454 cell redox homeostasis 2.708378e-3
GO:0007051 spindle organization 2.729832e-3
GO:0045786 negative regulation of cell cycle 2.768776e-3
GO:0046039 GTP metabolic process 2.833046e-3
GO:0051310 metaphase plate congression 2.855617e-3
GO:0007131 reciprocal meiotic recombination 2.880820e-3
GO:0042307 positive regulation of protein import into nucleus 2.914521e-3
GO:0048599 oocyte development 2.941288e-3
GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 2.951180e-3
GO:0043488 regulation of mRNA stability 3.029286e-3
GO:0035194 posttranscriptional gene silencing by RNA 3.042469e-3
GO:0042053 regulation of dopamine metabolic process 3.096876e-3
GO:0051382 kinetochore assembly 3.098375e-3
GO:0042823 pyridoxal phosphate biosynthetic process 3.098375e-3
GO:0001880 Mullerian duct regression 3.113738e-3
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 3.129654e-3
GO:0050928 negative regulation of positive chemotaxis 3.129654e-3
GO:0070846 Hsp90 deacetylation 3.129654e-3
GO:0090042 tubulin deacetylation 3.129654e-3
GO:0032543 mitochondrial translation 3.129654e-3
GO:0000379 tRNA-type intron splice site recognition and cleavage 3.129654e-3
GO:0019428 allantoin biosynthetic process 3.129654e-3
GO:0019858 cytosine metabolic process 3.129654e-3
GO:0010556 regulation of macromolecule biosynthetic process 3.158203e-3
GO:0060606 tube closure 3.168331e-3
GO:0009186 deoxyribonucleoside diphosphate metabolic process 3.194546e-3
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine 3.313199e-3
GO:0006904 vesicle docking involved in exocytosis 3.313395e-3
GO:0048665 neuron fate specification 3.331422e-3
GO:0033084 regulation of immature T cell proliferation in thymus 3.383996e-3
GO:0045647 negative regulation of erythrocyte differentiation 3.400928e-3
GO:0032289 central nervous system myelin formation 3.411939e-3
GO:0002009 morphogenesis of an epithelium 3.448056e-3
GO:0010564 regulation of cell cycle process 3.481776e-3
GO:0032571 response to vitamin K 3.508146e-3
GO:0060425 lung morphogenesis 3.602638e-3
GO:0035195 gene silencing by miRNA 3.638161e-3
GO:0007141 male meiosis I 3.664103e-3
GO:0042424 catecholamine catabolic process 3.683894e-3
GO:0006116 NADH oxidation 3.683894e-3
GO:0042069 regulation of catecholamine metabolic process 3.760095e-3
GO:0001843 neural tube closure 3.905774e-3
GO:0006654 phosphatidic acid biosynthetic process 3.907311e-3
GO:0006355 regulation of transcription, DNA-dependent 3.913669e-3
GO:0043046 DNA methylation involved in gamete generation 3.924012e-3
GO:0033261 regulation of S phase 3.930240e-3
GO:0043009 chordate embryonic development 3.993760e-3
GO:0019219 regulation of nucleobase-containing compound metabolic process 4.031562e-3
GO:0048630 skeletal muscle tissue growth 4.044282e-3
GO:0010659 cardiac muscle cell apoptosis 4.052972e-3
GO:0002541 activation of plasma proteins involved in acute inflammatory response 4.052972e-3
GO:0009817 defense response to fungus, incompatible interaction 4.052972e-3
GO:0055118 negative regulation of cardiac muscle contraction 4.185637e-3
GO:0006259 DNA metabolic process 4.206751e-3
GO:0048285 organelle fission 4.289841e-3
GO:0044065 regulation of respiratory system process 4.308961e-3
GO:0061304 retinal blood vessel morphogenesis 4.348816e-3
GO:0008608 attachment of spindle microtubules to kinetochore 4.348816e-3
GO:2000677 regulation of transcription regulatory region DNA binding 4.558878e-3
GO:0043487 regulation of RNA stability 4.605956e-3
GO:0006220 pyrimidine nucleotide metabolic process 4.638270e-3
GO:0042993 positive regulation of transcription factor import into nucleus 4.823843e-3
GO:0070936 protein K48-linked ubiquitination 4.833820e-3
GO:0000209 protein polyubiquitination 4.928490e-3
GO:0009219 pyrimidine deoxyribonucleotide metabolic process 5.060477e-3
GO:0046827 positive regulation of protein export from nucleus 5.132853e-3
GO:0043148 mitotic spindle stabilization 5.146734e-3
GO:0007389 pattern specification process 5.152754e-3
GO:0070918 production of small RNA involved in gene silencing by RNA 5.156108e-3
GO:0051171 regulation of nitrogen compound metabolic process 5.250731e-3
GO:0071173 spindle assembly checkpoint 5.271314e-3
GO:0010608 posttranscriptional regulation of gene expression 5.306910e-3
GO:0006730 one-carbon metabolic process 5.332233e-3
GO:0003357 noradrenergic neuron differentiation 5.424195e-3
GO:0034968 histone lysine methylation 5.513437e-3
GO:0006651 diacylglycerol biosynthetic process 5.627999e-3
GO:0030262 apoptotic nuclear change 5.656280e-3
GO:0046164 alcohol catabolic process 5.663539e-3
GO:0009081 branched chain family amino acid metabolic process 5.752189e-3
GO:0051058 negative regulation of small GTPase mediated signal transduction 5.762573e-3
GO:2000344 positive regulation of acrosome reaction 5.818692e-3
GO:0070192 chromosome organization involved in meiosis 5.935161e-3
GO:0019320 hexose catabolic process 5.959020e-3
GO:0045143 homologous chromosome segregation 6.011328e-3
GO:0009994 oocyte differentiation 6.057043e-3
GO:0070163 regulation of adiponectin secretion 6.155250e-3
GO:0007196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway 6.155250e-3
GO:0010389 regulation of G2/M transition of mitotic cell cycle 6.171295e-3
GO:0090305 nucleic acid phosphodiester bond hydrolysis 6.254165e-3
GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter 6.261230e-3
GO:0072362 regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter 6.261230e-3
GO:0006931 substrate-dependent cell migration, cell attachment to substrate 6.261230e-3
GO:0046580 negative regulation of Ras protein signal transduction 6.299394e-3
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 6.345232e-3
GO:0042667 auditory receptor cell fate specification 6.345232e-3
GO:0014895 smooth muscle hypertrophy 6.345232e-3
GO:0045609 positive regulation of auditory receptor cell differentiation 6.345232e-3
GO:0060975 cardioblast migration to the midline involved in heart field formation 6.345232e-3
GO:0003106 negative regulation of glomerular filtration by angiotensin 6.345232e-3
GO:0009438 methylglyoxal metabolic process 6.345232e-3
GO:0003210 cardiac atrium formation 6.345232e-3
GO:0003259 cardioblast anterior-lateral migration 6.345232e-3
GO:0003236 sinus venosus morphogenesis 6.345232e-3
GO:0007050 cell cycle arrest 6.427692e-3
GO:0060441 epithelial tube branching involved in lung morphogenesis 6.448931e-3
GO:0044260 cellular macromolecule metabolic process 6.488268e-3
GO:0002268 follicular dendritic cell differentiation 6.488636e-3
GO:0031577 spindle checkpoint 6.528231e-3
GO:0010467 gene expression 6.597097e-3
GO:0048278 vesicle docking 6.667013e-3
GO:0033083 regulation of immature T cell proliferation 6.692635e-3
GO:0000956 nuclear-transcribed mRNA catabolic process 6.742439e-3
GO:0035567 non-canonical Wnt receptor signaling pathway 6.747859e-3
GO:0051568 histone H3-K4 methylation 6.805584e-3
GO:0016197 endosome transport 6.951615e-3
GO:0006308 DNA catabolic process 7.007404e-3
GO:0045814 negative regulation of gene expression, epigenetic 7.017958e-3
GO:0006098 pentose-phosphate shunt 7.064511e-3
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 7.188166e-3
GO:0016075 rRNA catabolic process 7.188166e-3
GO:0014020 primary neural tube formation 7.205374e-3
GO:0007126 meiosis 7.244605e-3
GO:0048663 neuron fate commitment 7.320300e-3
GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade 7.494484e-3
GO:0006184 GTP catabolic process 7.764164e-3
GO:0070634 transepithelial ammonium transport 7.790155e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 7.839173e-3
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 7.891432e-3
GO:0035196 production of miRNAs involved in gene silencing by miRNA 7.907491e-3
GO:0046069 cGMP catabolic process 7.922117e-3
GO:0016180 snRNA processing 7.922117e-3
GO:0070534 protein K63-linked ubiquitination 7.979897e-3
GO:0051656 establishment of organelle localization 7.987086e-3
GO:0072488 ammonium transmembrane transport 8.103883e-3
GO:0060376 positive regulation of mast cell differentiation 8.329761e-3
GO:0008611 ether lipid biosynthetic process 8.329761e-3
GO:0002537 nitric oxide production involved in inflammatory response 8.329761e-3
GO:0010225 response to UV-C 8.460511e-3
GO:0006260 DNA replication 8.465528e-3
GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry 8.553446e-3
GO:0051313 attachment of spindle microtubules to chromosome 8.603153e-3
GO:0048387 negative regulation of retinoic acid receptor signaling pathway 8.634695e-3
GO:0010002 cardioblast differentiation 8.845614e-3
GO:0051303 establishment of chromosome localization 8.931236e-3
GO:0051169 nuclear transport 8.997445e-3
GO:0031047 gene silencing by RNA 9.054794e-3
GO:0006086 acetyl-CoA biosynthetic process from pyruvate 9.068671e-3
GO:0090234 regulation of kinetochore assembly 9.098365e-3
GO:0090169 regulation of spindle assembly 9.098365e-3
GO:0001705 ectoderm formation 9.098365e-3
GO:0002030 inhibitory G-protein coupled receptor phosphorylation 9.098365e-3
GO:0007060 male meiosis chromosome segregation 9.098365e-3
GO:0032229 negative regulation of synaptic transmission, GABAergic 9.184412e-3
GO:0006450 regulation of translational fidelity 9.400437e-3
GO:0048026 positive regulation of nuclear mRNA splicing, via spliceosome 9.429530e-3
GO:0006346 methylation-dependent chromatin silencing 9.429530e-3
GO:0009792 embryo development ending in birth or egg hatching 9.451138e-3
GO:0043001 Golgi to plasma membrane protein transport 9.960257e-3
GO:0045014 negative regulation of transcription by glucose 1.001921e-2
GO:0006515 misfolded or incompletely synthesized protein catabolic process 1.001921e-2
GO:0032914 positive regulation of transforming growth factor beta1 production 1.008102e-2
GO:0006921 cellular component disassembly involved in apoptosis 1.011850e-2
GO:0045880 positive regulation of smoothened signaling pathway 1.017691e-2
GO:0045084 positive regulation of interleukin-12 biosynthetic process 1.031250e-2
GO:0034587 piRNA metabolic process 1.055067e-2
GO:0032508 DNA duplex unwinding 1.060413e-2
GO:0032981 mitochondrial respiratory chain complex I assembly 1.060860e-2
GO:0042761 very long-chain fatty acid biosynthetic process 1.071266e-2
GO:0060466 activation of meiosis involved in egg activation 1.076443e-2
GO:0009452 RNA capping 1.076443e-2
GO:0050774 negative regulation of dendrite morphogenesis 1.076443e-2
GO:2000001 regulation of DNA damage checkpoint 1.076786e-2
GO:0070368 positive regulation of hepatocyte differentiation 1.076786e-2
GO:0031268 pseudopodium organization 1.076786e-2
GO:0014805 smooth muscle adaptation 1.076786e-2
GO:0043271 negative regulation of ion transport 1.080366e-2
GO:0071479 cellular response to ionizing radiation 1.085212e-2
GO:0006401 RNA catabolic process 1.095554e-2
GO:0042345 regulation of NF-kappaB import into nucleus 1.109736e-2
GO:0032727 positive regulation of interferon-alpha production 1.110147e-2
GO:0002513 tolerance induction to self antigen 1.110147e-2
GO:0055119 relaxation of cardiac muscle 1.131033e-2
GO:0006729 tetrahydrobiopterin biosynthetic process 1.131033e-2
GO:0007127 meiosis I 1.147189e-2
GO:0002089 lens morphogenesis in camera-type eye 1.147189e-2
GO:0006913 nucleocytoplasmic transport 1.157392e-2
GO:0032845 negative regulation of homeostatic process 1.159731e-2
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 1.171952e-2
GO:0060437 lung growth 1.174000e-2
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 1.174000e-2
GO:0033683 nucleotide-excision repair, DNA incision 1.205789e-2
GO:0060028 convergent extension involved in axis elongation 1.205789e-2
GO:0033132 negative regulation of glucokinase activity 1.205789e-2
GO:0019405 alditol catabolic process 1.205789e-2
GO:0016073 snRNA metabolic process 1.207634e-2
GO:0006646 phosphatidylethanolamine biosynthetic process 1.226024e-2
GO:0072513 positive regulation of secondary heart field cardioblast proliferation 1.226943e-2
GO:0006417 regulation of translation 1.234666e-2
GO:0045132 meiotic chromosome segregation 1.260746e-2
GO:0035721 intraflagellar retrograde transport 1.269762e-2
GO:0017187 peptidyl-glutamic acid carboxylation 1.269762e-2
GO:0061015 snRNA import into nucleus 1.269762e-2
GO:0009443 pyridoxal 5'-phosphate salvage 1.269762e-2
GO:0006683 galactosylceramide catabolic process 1.269762e-2
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 1.271061e-2
GO:0018120 peptidyl-arginine ADP-ribosylation 1.271061e-2
GO:0000075 cell cycle checkpoint 1.271329e-2
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 1.282244e-2
GO:0051383 kinetochore organization 1.282244e-2
GO:0046501 protoporphyrinogen IX metabolic process 1.282244e-2
GO:0051584 regulation of dopamine uptake 1.299329e-2
GO:0034508 centromere complex assembly 1.299329e-2
GO:0090212 negative regulation of establishment of blood-brain barrier 1.301420e-2
GO:2000781 positive regulation of double-strand break repair 1.301420e-2
GO:0015969 guanosine tetraphosphate metabolic process 1.301420e-2
GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity 1.301420e-2
GO:0090168 Golgi reassembly 1.301420e-2
GO:0001546 preantral ovarian follicle growth 1.301420e-2
GO:0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction 1.301420e-2
GO:0007100 mitotic centrosome separation 1.301420e-2
GO:0009236 cobalamin biosynthetic process 1.301420e-2
GO:0007506 gonadal mesoderm development 1.301420e-2
GO:0001710 mesodermal cell fate commitment 1.301878e-2
GO:0035520 monoubiquitinated protein deubiquitination 1.317081e-2
GO:0032525 somite rostral/caudal axis specification 1.351671e-2
GO:0042474 middle ear morphogenesis 1.353746e-2
GO:0031345 negative regulation of cell projection organization 1.394140e-2
GO:0072110 glomerular mesangial cell proliferation 1.395486e-2
GO:0048755 branching morphogenesis of a nerve 1.395486e-2
GO:0070734 histone H3-K27 methylation 1.395486e-2
GO:0015879 carnitine transport 1.395486e-2
GO:0045116 protein neddylation 1.395486e-2
GO:0032392 DNA geometric change 1.396925e-2
GO:0007431 salivary gland development 1.401307e-2
GO:0033157 regulation of intracellular protein transport 1.406763e-2
GO:0006573 valine metabolic process 1.418399e-2
GO:0046544 development of secondary male sexual characteristics 1.418449e-2
GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly 1.418449e-2
GO:0006007 glucose catabolic process 1.435091e-2
GO:0030307 positive regulation of cell growth 1.449907e-2
GO:0000070 mitotic sister chromatid segregation 1.461810e-2
GO:0002053 positive regulation of mesenchymal cell proliferation 1.542488e-2
GO:0006304 DNA modification 1.565442e-2
GO:0043653 mitochondrial fragmentation involved in apoptosis 1.567859e-2
GO:0035441 cell migration involved in vasculogenesis 1.567859e-2
GO:0034453 microtubule anchoring 1.570448e-2
GO:0032020 ISG15-protein conjugation 1.582361e-2
GO:0051386 regulation of nerve growth factor receptor signaling pathway 1.594218e-2
GO:0051320 S phase 1.594218e-2
GO:0042119 neutrophil activation 1.594218e-2
GO:0002072 optic cup morphogenesis involved in camera-type eye development 1.594856e-2
GO:0009133 nucleoside diphosphate biosynthetic process 1.617220e-2
GO:0033239 negative regulation of cellular amine metabolic process 1.629253e-2
GO:0033233 regulation of protein sumoylation 1.633955e-2
GO:0046365 monosaccharide catabolic process 1.640499e-2
GO:0045066 regulatory T cell differentiation 1.642858e-2
GO:0015696 ammonium transport 1.642858e-2
GO:0072091 regulation of stem cell proliferation 1.643754e-2
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 1.643754e-2
GO:0048385 regulation of retinoic acid receptor signaling pathway 1.656857e-2
GO:0048536 spleen development 1.679080e-2
GO:0021695 cerebellar cortex development 1.692097e-2
GO:0033092 positive regulation of immature T cell proliferation in thymus 1.704433e-2
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 1.707332e-2
GO:0045759 negative regulation of action potential 1.707332e-2
GO:0000729 DNA double-strand break processing 1.707332e-2
GO:0000414 regulation of histone H3-K36 methylation 1.707332e-2
GO:0032507 maintenance of protein location in cell 1.711377e-2
GO:0030497 fatty acid elongation 1.720411e-2
GO:0006997 nucleus organization 1.721826e-2
GO:0045064 T-helper 2 cell differentiation 1.727901e-2
GO:0071585 detoxification of cadmium ion 1.727901e-2
GO:0032456 endocytic recycling 1.732816e-2
GO:0043114 regulation of vascular permeability 1.784791e-2
GO:0006269 DNA replication, synthesis of RNA primer 1.786397e-2
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 1.791679e-2
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 1.791679e-2
GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway 1.814723e-2
GO:0032608 interferon-beta production 1.814723e-2
GO:0046092 deoxycytidine metabolic process 1.814723e-2
GO:0000080 G1 phase of mitotic cell cycle 1.839330e-2
GO:2000778 positive regulation of interleukin-6 secretion 1.848237e-2
GO:0061301 cerebellum vasculature morphogenesis 1.848237e-2
GO:0030421 defecation 1.848237e-2
GO:0051466 positive regulation of corticotropin-releasing hormone secretion 1.848237e-2
GO:0071174 mitotic cell cycle spindle checkpoint 1.850381e-2
GO:0051318 G1 phase 1.854423e-2
GO:0034661 ncRNA catabolic process 1.873947e-2
GO:0009451 RNA modification 1.914799e-2
GO:0007030 Golgi organization 1.918185e-2
GO:0014032 neural crest cell development 1.921453e-2
GO:0010457 centriole-centriole cohesion 1.947706e-2
GO:0007129 synapsis 1.949225e-2
GO:0090183 regulation of kidney development 1.953250e-2
GO:0051642 centrosome localization 1.986361e-2
GO:0050680 negative regulation of epithelial cell proliferation 1.999296e-2
GO:0033578 protein glycosylation in Golgi 2.003643e-2
GO:0070102 interleukin-6-mediated signaling pathway 2.003888e-2
GO:0032825 positive regulation of natural killer cell differentiation 2.003888e-2
GO:0017145 stem cell division 2.043119e-2
GO:0022406 membrane docking 2.043851e-2
GO:0048484 enteric nervous system development 2.051244e-2