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Novel motif:49

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name:motif49_ACAGRG

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0050896 response to stimulus 2.662629e-43
GO:0007154 cell communication 2.255728e-41
GO:0023052 signaling 2.313434e-41
GO:0048583 regulation of response to stimulus 4.633373e-41
GO:0007165 signal transduction 1.137537e-40
GO:0006955 immune response 4.535971e-39
GO:0051716 cellular response to stimulus 1.203345e-37
GO:0006952 defense response 1.432362e-37
GO:0002376 immune system process 1.808973e-34
GO:0007166 cell surface receptor linked signaling pathway 1.639951e-30
GO:0065007 biological regulation 5.006086e-29
GO:0048584 positive regulation of response to stimulus 4.095686e-27
GO:0002684 positive regulation of immune system process 5.148641e-27
GO:0002682 regulation of immune system process 7.826931e-27
GO:0050789 regulation of biological process 3.670727e-26
GO:0006954 inflammatory response 3.382461e-25
GO:0006909 phagocytosis 3.298994e-22
GO:0048518 positive regulation of biological process 5.329200e-22
GO:0023051 regulation of signaling 2.028599e-21
GO:0042221 response to chemical stimulus 2.191983e-21
GO:0009966 regulation of signal transduction 2.763244e-21
GO:0032501 multicellular organismal process 3.801703e-21
GO:0006950 response to stress 2.996636e-19
GO:0035556 intracellular signal transduction 4.372925e-19
GO:0032101 regulation of response to external stimulus 8.656977e-19
GO:0065008 regulation of biological quality 1.251789e-18
GO:0050776 regulation of immune response 1.424161e-18
GO:0070613 regulation of protein processing 2.095519e-18
GO:0050794 regulation of cellular process 6.613466e-18
GO:0007155 cell adhesion 1.948671e-17
GO:0009628 response to abiotic stimulus 3.100842e-17
GO:0009605 response to external stimulus 7.622679e-17
GO:0010466 negative regulation of peptidase activity 2.368275e-16
GO:0050778 positive regulation of immune response 3.934298e-16
GO:0010951 negative regulation of endopeptidase activity 6.407896e-16
GO:0043067 regulation of programmed cell death 1.491756e-15
GO:0001817 regulation of cytokine production 2.946184e-15
GO:0051346 negative regulation of hydrolase activity 3.754706e-15
GO:0010941 regulation of cell death 4.261596e-15
GO:0042981 regulation of apoptosis 4.970008e-15
GO:0048522 positive regulation of cellular process 1.170524e-14
GO:0032103 positive regulation of response to external stimulus 1.399675e-14
GO:0010955 negative regulation of protein processing 1.970096e-14
GO:0002696 positive regulation of leukocyte activation 4.873963e-14
GO:0001819 positive regulation of cytokine production 5.013294e-14
GO:0009611 response to wounding 5.060214e-14
GO:0045087 innate immune response 7.356274e-14
GO:0003008 system process 8.113644e-14
GO:0010646 regulation of cell communication 1.025065e-13
GO:0002253 activation of immune response 1.026676e-13
GO:0061024 membrane organization 1.758147e-13
GO:0050867 positive regulation of cell activation 1.847178e-13
GO:0016044 cellular membrane organization 1.991379e-13
GO:0007586 digestion 2.100270e-13
GO:0051897 positive regulation of protein kinase B signaling cascade 2.330916e-13
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.412716e-13
GO:0010740 positive regulation of intracellular protein kinase cascade 3.585449e-13
GO:0051896 regulation of protein kinase B signaling cascade 4.123303e-13
GO:0009987 cellular process 4.214668e-13
GO:0002697 regulation of immune effector process 5.033348e-13
GO:0002577 regulation of antigen processing and presentation 5.038727e-13
GO:0051336 regulation of hydrolase activity 5.055207e-13
GO:0030449 regulation of complement activation 5.203989e-13
GO:0016064 immunoglobulin mediated immune response 5.340259e-13
GO:0031347 regulation of defense response 6.001832e-13
GO:0002407 dendritic cell chemotaxis 7.462457e-13
GO:0072376 protein activation cascade 8.298594e-13
GO:0002604 regulation of dendritic cell antigen processing and presentation 8.407073e-13
GO:0034754 cellular hormone metabolic process 1.045209e-12
GO:0050920 regulation of chemotaxis 1.453443e-12
GO:0050795 regulation of behavior 1.823680e-12
GO:0016192 vesicle-mediated transport 2.193722e-12
GO:0080134 regulation of response to stress 2.385770e-12
GO:0051234 establishment of localization 3.028698e-12
GO:0010288 response to lead ion 3.076140e-12
GO:0019221 cytokine-mediated signaling pathway 3.462865e-12
GO:0032879 regulation of localization 3.631918e-12
GO:0048520 positive regulation of behavior 4.217991e-12
GO:0051179 localization 4.697349e-12
GO:0050727 regulation of inflammatory response 5.765037e-12
GO:0006953 acute-phase response 6.795879e-12
GO:0006956 complement activation 7.029872e-12
GO:0030335 positive regulation of cell migration 8.369835e-12
GO:0010033 response to organic substance 8.547848e-12
GO:0002250 adaptive immune response 8.642303e-12
GO:2000147 positive regulation of cell motility 8.879649e-12
GO:0019724 B cell mediated immunity 9.050831e-12
GO:0042445 hormone metabolic process 1.098122e-11
GO:0006897 endocytosis 1.455855e-11
GO:0002690 positive regulation of leukocyte chemotaxis 1.816538e-11
GO:0002687 positive regulation of leukocyte migration 2.166431e-11
GO:0007167 enzyme linked receptor protein signaling pathway 3.503099e-11
GO:0006810 transport 3.916732e-11
GO:0030198 extracellular matrix organization 3.920989e-11
GO:0000093 mitotic telophase 3.926441e-11
GO:0046626 regulation of insulin receptor signaling pathway 4.096876e-11
GO:0032908 regulation of transforming growth factor beta1 production 4.637483e-11
GO:0000302 response to reactive oxygen species 4.807728e-11
GO:0045321 leukocyte activation 5.666786e-11
GO:0050921 positive regulation of chemotaxis 6.623734e-11
GO:0002920 regulation of humoral immune response 6.701273e-11
GO:0006775 fat-soluble vitamin metabolic process 7.133440e-11
GO:0043206 fibril organization 9.759097e-11
GO:0002449 lymphocyte mediated immunity 1.171223e-10
GO:0002252 immune effector process 1.268274e-10
GO:0050870 positive regulation of T cell activation 1.289057e-10
GO:0006959 humoral immune response 1.305235e-10
GO:0044281 small molecule metabolic process 1.377214e-10
GO:0051272 positive regulation of cellular component movement 1.671124e-10
GO:0031295 T cell costimulation 1.766607e-10
GO:0009607 response to biotic stimulus 2.246957e-10
GO:0040017 positive regulation of locomotion 2.259519e-10
GO:0007600 sensory perception 2.343225e-10
GO:0009266 response to temperature stimulus 2.522262e-10
GO:0051251 positive regulation of lymphocyte activation 2.716920e-10
GO:0002443 leukocyte mediated immunity 2.882733e-10
GO:0006935 chemotaxis 3.035946e-10
GO:0030334 regulation of cell migration 3.168612e-10
GO:0030595 leukocyte chemotaxis 3.293251e-10
GO:0042592 homeostatic process 3.404881e-10
GO:0044258 intestinal lipid catabolic process 3.923704e-10
GO:0018350 protein esterification 3.923704e-10
GO:0009749 response to glucose stimulus 4.645109e-10
GO:0050877 neurological system process 5.840463e-10
GO:0031667 response to nutrient levels 5.931567e-10
GO:2000145 regulation of cell motility 6.379312e-10
GO:0045834 positive regulation of lipid metabolic process 8.533962e-10
GO:0007186 G-protein coupled receptor protein signaling pathway 8.598613e-10
GO:0071636 positive regulation of transforming growth factor beta production 9.438701e-10
GO:0002455 humoral immune response mediated by circulating immunoglobulin 9.880513e-10
GO:0050790 regulation of catalytic activity 1.079107e-9
GO:0010817 regulation of hormone levels 1.160536e-9
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.194595e-9
GO:0006917 induction of apoptosis 1.225991e-9
GO:0071622 regulation of granulocyte chemotaxis 1.229261e-9
GO:0002688 regulation of leukocyte chemotaxis 1.252898e-9
GO:0010627 regulation of intracellular protein kinase cascade 1.261972e-9
GO:0051049 regulation of transport 1.405015e-9
GO:0003334 keratinocyte development 1.425836e-9
GO:0048545 response to steroid hormone stimulus 1.430835e-9
GO:0043086 negative regulation of catalytic activity 1.463341e-9
GO:0002685 regulation of leukocyte migration 1.624668e-9
GO:0034097 response to cytokine stimulus 1.797293e-9
GO:0008228 opsonization 1.799320e-9
GO:0051270 regulation of cellular component movement 1.872094e-9
GO:0006958 complement activation, classical pathway 1.901454e-9
GO:0052547 regulation of peptidase activity 1.983015e-9
GO:0046314 phosphocreatine biosynthetic process 2.044602e-9
GO:0002526 acute inflammatory response 2.158028e-9
GO:0007243 intracellular protein kinase cascade 2.193298e-9
GO:0008202 steroid metabolic process 2.334563e-9
GO:0002579 positive regulation of antigen processing and presentation 2.482332e-9
GO:0012502 induction of programmed cell death 2.521046e-9
GO:0045916 negative regulation of complement activation 2.540888e-9
GO:0051707 response to other organism 2.562073e-9
GO:0009967 positive regulation of signal transduction 2.609757e-9
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 2.665939e-9
GO:0009408 response to heat 2.913020e-9
GO:0043085 positive regulation of catalytic activity 3.273912e-9
GO:0043405 regulation of MAP kinase activity 3.307683e-9
GO:0007264 small GTPase mediated signal transduction 3.337601e-9
GO:0071902 positive regulation of protein serine/threonine kinase activity 3.341233e-9
GO:0010759 positive regulation of macrophage chemotaxis 3.537352e-9
GO:0040012 regulation of locomotion 3.751581e-9
GO:0043900 regulation of multi-organism process 3.908968e-9
GO:0002764 immune response-regulating signaling pathway 4.047644e-9
GO:0043277 apoptotic cell clearance 4.166856e-9
GO:0070887 cellular response to chemical stimulus 4.365455e-9
GO:0016525 negative regulation of angiogenesis 4.755084e-9
GO:0002694 regulation of leukocyte activation 4.884613e-9
GO:0071702 organic substance transport 5.043639e-9
GO:0071634 regulation of transforming growth factor beta production 5.190808e-9
GO:0042108 positive regulation of cytokine biosynthetic process 5.350021e-9
GO:0050729 positive regulation of inflammatory response 5.454441e-9
GO:0042137 sequestering of neurotransmitter 6.110616e-9
GO:0060696 regulation of phospholipid catabolic process 6.151291e-9
GO:0006968 cellular defense response 6.480506e-9
GO:0033189 response to vitamin A 6.998545e-9
GO:0051480 cytosolic calcium ion homeostasis 7.129520e-9
GO:0007267 cell-cell signaling 7.318684e-9
GO:0042363 fat-soluble vitamin catabolic process 7.393902e-9
GO:0051239 regulation of multicellular organismal process 7.767068e-9
GO:0009617 response to bacterium 7.821952e-9
GO:0050865 regulation of cell activation 8.230419e-9
GO:0032914 positive regulation of transforming growth factor beta1 production 9.876844e-9
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.012546e-8
GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development 1.348522e-8
GO:0006629 lipid metabolic process 1.432202e-8
GO:0010758 regulation of macrophage chemotaxis 1.435735e-8
GO:0048585 negative regulation of response to stimulus 1.481847e-8
GO:0051051 negative regulation of transport 1.499125e-8
GO:0000165 MAPKKK cascade 1.581930e-8
GO:0043406 positive regulation of MAP kinase activity 1.744686e-8
GO:0021984 adenohypophysis development 1.843660e-8
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.976968e-8
GO:0015872 dopamine transport 2.151563e-8
GO:0030155 regulation of cell adhesion 2.357828e-8
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 2.435076e-8
GO:0032456 endocytic recycling 2.437485e-8
GO:2000465 regulation of glycogen (starch) synthase activity 2.440514e-8
GO:0051591 response to cAMP 2.578382e-8
GO:0007522 visceral muscle development 2.858260e-8
GO:0000090 mitotic anaphase 3.005079e-8
GO:0051657 maintenance of organelle location 3.414288e-8
GO:0051704 multi-organism process 3.481408e-8
GO:0033273 response to vitamin 3.612947e-8
GO:0060326 cell chemotaxis 3.664916e-8
GO:0032368 regulation of lipid transport 3.788049e-8
GO:0006776 vitamin A metabolic process 3.966484e-8
GO:0019882 antigen processing and presentation 4.194731e-8
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 4.229884e-8
GO:0031349 positive regulation of defense response 4.273058e-8
GO:0045112 integrin biosynthetic process 4.333959e-8
GO:0023056 positive regulation of signaling 4.404613e-8
GO:0043068 positive regulation of programmed cell death 4.429085e-8
GO:0010812 negative regulation of cell-substrate adhesion 4.605864e-8
GO:0007204 elevation of cytosolic calcium ion concentration 4.619901e-8
GO:0042742 defense response to bacterium 4.815001e-8
GO:0032536 regulation of cell projection size 4.865207e-8
GO:0044240 multicellular organismal lipid catabolic process 5.260233e-8
GO:0008219 cell death 5.599776e-8
GO:0010757 negative regulation of plasminogen activation 5.826039e-8
GO:0002757 immune response-activating signal transduction 5.898467e-8
GO:0002544 chronic inflammatory response 6.096515e-8
GO:0015849 organic acid transport 6.229272e-8
GO:0042104 positive regulation of activated T cell proliferation 6.377400e-8
GO:0010755 regulation of plasminogen activation 6.540082e-8
GO:0009746 response to hexose stimulus 6.703632e-8
GO:0044236 multicellular organismal metabolic process 6.753439e-8
GO:0006820 anion transport 6.816041e-8
GO:0032502 developmental process 6.958514e-8
GO:0010647 positive regulation of cell communication 7.266258e-8
GO:2000467 positive regulation of glycogen (starch) synthase activity 7.825251e-8
GO:0016265 death 8.189529e-8
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 8.797780e-8
GO:0045730 respiratory burst 8.875120e-8
GO:0052548 regulation of endopeptidase activity 9.166014e-8
GO:0001503 ossification 9.323522e-8
GO:0046942 carboxylic acid transport 9.370548e-8
GO:0050764 regulation of phagocytosis 9.839418e-8
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 9.889370e-8
GO:0061025 membrane fusion 1.046112e-7
GO:0050863 regulation of T cell activation 1.077906e-7
GO:0033674 positive regulation of kinase activity 1.085229e-7
GO:0006944 cellular membrane fusion 1.091377e-7
GO:0002149 hypochlorous acid biosynthetic process 1.096679e-7
GO:0035411 catenin import into nucleus 1.100971e-7
GO:0002821 positive regulation of adaptive immune response 1.132814e-7
GO:0043410 positive regulation of MAPKKK cascade 1.161912e-7
GO:0002922 positive regulation of humoral immune response 1.172766e-7
GO:0009991 response to extracellular stimulus 1.199156e-7
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.199565e-7
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 1.219335e-7
GO:0065009 regulation of molecular function 1.319294e-7
GO:0010942 positive regulation of cell death 1.367116e-7
GO:0032946 positive regulation of mononuclear cell proliferation 1.420314e-7
GO:0071345 cellular response to cytokine stimulus 1.457338e-7
GO:0051240 positive regulation of multicellular organismal process 1.536556e-7
GO:0043065 positive regulation of apoptosis 1.545834e-7
GO:0014012 peripheral nervous system axon regeneration 1.565243e-7
GO:0051056 regulation of small GTPase mediated signal transduction 1.599525e-7
GO:0034284 response to monosaccharide stimulus 1.601024e-7
GO:0045717 negative regulation of fatty acid biosynthetic process 1.688709e-7
GO:0044093 positive regulation of molecular function 1.707065e-7
GO:0050829 defense response to Gram-negative bacterium 1.732389e-7
GO:0048878 chemical homeostasis 1.738716e-7
GO:0010763 positive regulation of fibroblast migration 1.754288e-7
GO:0071675 regulation of mononuclear cell migration 1.762402e-7
GO:0009071 serine family amino acid catabolic process 1.811338e-7
GO:0010631 epithelial cell migration 1.816352e-7
GO:0046724 oxalic acid secretion 1.905134e-7
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate 1.905134e-7
GO:0060600 dichotomous subdivision of an epithelial terminal unit 2.001382e-7
GO:0051347 positive regulation of transferase activity 2.019055e-7
GO:0008624 induction of apoptosis by extracellular signals 2.039008e-7
GO:0046628 positive regulation of insulin receptor signaling pathway 2.404449e-7
GO:0043030 regulation of macrophage activation 2.454578e-7
GO:0002886 regulation of myeloid leukocyte mediated immunity 2.464667e-7
GO:0006915 apoptosis 2.586908e-7
GO:0005979 regulation of glycogen biosynthetic process 2.667813e-7
GO:0071732 cellular response to nitric oxide 2.687527e-7
GO:0044130 negative regulation of growth of symbiont in host 2.764253e-7
GO:0051534 negative regulation of NFAT protein import into nucleus 2.822977e-7
GO:0034763 negative regulation of transmembrane transport 2.931220e-7
GO:0000187 activation of MAPK activity 2.949649e-7
GO:0009612 response to mechanical stimulus 2.951681e-7
GO:0040011 locomotion 3.026593e-7
GO:0015721 bile acid and bile salt transport 3.052631e-7
GO:0045766 positive regulation of angiogenesis 3.061120e-7
GO:0006720 isoprenoid metabolic process 3.142136e-7
GO:0044341 sodium-dependent phosphate transport 3.483256e-7
GO:0070208 protein heterotrimerization 3.631755e-7
GO:0010900 negative regulation of phosphatidylcholine catabolic process 3.766380e-7
GO:0001775 cell activation 4.165970e-7
GO:0006721 terpenoid metabolic process 4.436866e-7
GO:0002883 regulation of hypersensitivity 4.509744e-7
GO:0050671 positive regulation of lymphocyte proliferation 4.583826e-7
GO:0032680 regulation of tumor necrosis factor production 4.785730e-7
GO:0007009 plasma membrane organization 4.811748e-7
GO:0009303 rRNA transcription 4.918293e-7
GO:0051937 catecholamine transport 5.058337e-7
GO:0071705 nitrogen compound transport 5.115689e-7
GO:0012501 programmed cell death 5.175916e-7
GO:0007584 response to nutrient 5.404254e-7
GO:0032370 positive regulation of lipid transport 5.453088e-7
GO:0001869 negative regulation of complement activation, lectin pathway 5.643841e-7
GO:0034762 regulation of transmembrane transport 6.059147e-7
GO:0044092 negative regulation of molecular function 6.327923e-7
GO:0051322 anaphase 6.376032e-7
GO:0006875 cellular metal ion homeostasis 6.407626e-7
GO:0010944 negative regulation of transcription by competitive promoter binding 6.601201e-7
GO:0035691 macrophage migration inhibitory factor signaling pathway 6.781648e-7
GO:0002673 regulation of acute inflammatory response 6.959888e-7
GO:0002699 positive regulation of immune effector process 6.995953e-7
GO:0045765 regulation of angiogenesis 7.099095e-7
GO:0002237 response to molecule of bacterial origin 7.120029e-7
GO:0090130 tissue migration 7.391799e-7
GO:0045725 positive regulation of glycogen biosynthetic process 7.444224e-7
GO:0055065 metal ion homeostasis 7.489950e-7
GO:0042990 regulation of transcription factor import into nucleus 7.588041e-7
GO:0043537 negative regulation of blood vessel endothelial cell migration 7.639601e-7
GO:0030100 regulation of endocytosis 7.909319e-7
GO:2000097 regulation of smooth muscle cell-matrix adhesion 8.109547e-7
GO:0003051 angiotensin-mediated drinking behavior 8.500477e-7
GO:0050690 regulation of defense response to virus by virus 8.516622e-7
GO:0016043 cellular component organization 8.674808e-7
GO:0032787 monocarboxylic acid metabolic process 8.934138e-7
GO:0010872 regulation of cholesterol esterification 9.051300e-7
GO:0006811 ion transport 9.410215e-7
GO:0042866 pyruvate biosynthetic process 9.637766e-7
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 9.753446e-7
GO:0006707 cholesterol catabolic process 9.947721e-7
GO:0006911 phagocytosis, engulfment 1.020873e-6
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1.046683e-6
GO:0045860 positive regulation of protein kinase activity 1.071193e-6
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 1.103155e-6
GO:0006766 vitamin metabolic process 1.120265e-6
GO:0002274 myeloid leukocyte activation 1.133223e-6
GO:0032526 response to retinoic acid 1.171011e-6
GO:0030277 maintenance of gastrointestinal epithelium 1.201207e-6
GO:2000191 regulation of fatty acid transport 1.231398e-6
GO:0042396 phosphagen biosynthetic process 1.322504e-6
GO:0042493 response to drug 1.356121e-6
GO:0060263 regulation of respiratory burst 1.358223e-6
GO:0070873 regulation of glycogen metabolic process 1.362380e-6
GO:0060346 bone trabecula formation 1.372568e-6
GO:0015844 monoamine transport 1.406564e-6
GO:0071310 cellular response to organic substance 1.421756e-6
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 1.508348e-6
GO:0007292 female gamete generation 1.603796e-6
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.606887e-6
GO:0002679 respiratory burst involved in defense response 1.609131e-6
GO:0009052 pentose-phosphate shunt, non-oxidative branch 1.627163e-6
GO:0002768 immune response-regulating cell surface receptor signaling pathway 1.630107e-6
GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger 1.662422e-6
GO:0003009 skeletal muscle contraction 1.743280e-6
GO:0051246 regulation of protein metabolic process 1.782520e-6
GO:0060548 negative regulation of cell death 1.837748e-6
GO:0071840 cellular component organization or biogenesis 1.861580e-6
GO:0010985 negative regulation of lipoprotein particle clearance 1.913511e-6
GO:0034014 response to triglyceride 1.947415e-6
GO:0070665 positive regulation of leukocyte proliferation 1.976846e-6
GO:0007601 visual perception 1.986315e-6
GO:0048519 negative regulation of biological process 2.017704e-6
GO:0031064 negative regulation of histone deacetylation 2.019141e-6
GO:0043588 skin development 2.054862e-6
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 2.069969e-6
GO:0050953 sensory perception of light stimulus 2.116564e-6
GO:0031133 regulation of axon diameter 2.147441e-6
GO:0031640 killing of cells of other organism 2.219993e-6
GO:0006140 regulation of nucleotide metabolic process 2.247920e-6
GO:0042534 regulation of tumor necrosis factor biosynthetic process 2.266293e-6
GO:0001953 negative regulation of cell-matrix adhesion 2.304058e-6
GO:0046006 regulation of activated T cell proliferation 2.312784e-6
GO:0070417 cellular response to cold 2.462038e-6
GO:0010718 positive regulation of epithelial to mesenchymal transition 2.561413e-6
GO:0045940 positive regulation of steroid metabolic process 2.640649e-6
GO:0051895 negative regulation of focal adhesion assembly 2.656535e-6
GO:0060351 cartilage development involved in endochondral bone morphogenesis 2.700585e-6
GO:0015809 arginine transport 2.816673e-6
GO:0090218 positive regulation of lipid kinase activity 2.842108e-6
GO:0008065 establishment of blood-nerve barrier 2.874411e-6
GO:0032496 response to lipopolysaccharide 2.891833e-6
GO:0032355 response to estradiol stimulus 2.953769e-6
GO:0010954 positive regulation of protein processing 2.973020e-6
GO:0046687 response to chromate 3.129875e-6
GO:0033986 response to methanol 3.129875e-6
GO:0007162 negative regulation of cell adhesion 3.181505e-6
GO:0034505 tooth mineralization 3.206368e-6
GO:0002478 antigen processing and presentation of exogenous peptide antigen 3.293177e-6
GO:0043066 negative regulation of apoptosis 3.335605e-6
GO:0042730 fibrinolysis 3.492859e-6
GO:0001516 prostaglandin biosynthetic process 3.596744e-6
GO:0002703 regulation of leukocyte mediated immunity 3.657894e-6
GO:0031099 regeneration 3.763747e-6
GO:0009629 response to gravity 3.807951e-6
GO:0019532 oxalate transport 3.872397e-6
GO:0070482 response to oxygen levels 4.148525e-6
GO:0006690 icosanoid metabolic process 4.212579e-6
GO:0043069 negative regulation of programmed cell death 4.224624e-6
GO:0014874 response to stimulus involved in regulation of muscle adaptation 4.234729e-6
GO:0046627 negative regulation of insulin receptor signaling pathway 4.262299e-6
GO:0007275 multicellular organismal development 4.451443e-6
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 4.521434e-6
GO:0006342 chromatin silencing 4.687867e-6
GO:0001523 retinoid metabolic process 4.814650e-6
GO:0042180 cellular ketone metabolic process 4.929393e-6
GO:0008207 C21-steroid hormone metabolic process 4.930655e-6
GO:0070875 positive regulation of glycogen metabolic process 4.966008e-6
GO:0042992 negative regulation of transcription factor import into nucleus 5.187550e-6
GO:0019884 antigen processing and presentation of exogenous antigen 5.207343e-6
GO:0050688 regulation of defense response to virus 5.284285e-6
GO:0006544 glycine metabolic process 5.288338e-6
GO:0043535 regulation of blood vessel endothelial cell migration 5.910776e-6
GO:0016458 gene silencing 6.047348e-6
GO:0006874 cellular calcium ion homeostasis 6.092462e-6
GO:0010754 negative regulation of cGMP-mediated signaling 6.166409e-6
GO:0043652 engulfment of apoptotic cell 6.166409e-6
GO:0010751 negative regulation of nitric oxide mediated signal transduction 6.166409e-6
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 6.166409e-6
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 6.166409e-6
GO:0031960 response to corticosteroid stimulus 6.317746e-6
GO:0033121 regulation of purine nucleotide catabolic process 6.636451e-6
GO:0002906 negative regulation of mature B cell apoptosis 6.776310e-6
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 6.793656e-6
GO:0042572 retinol metabolic process 6.859940e-6
GO:0030003 cellular cation homeostasis 6.961812e-6
GO:0031103 axon regeneration 7.015411e-6
GO:0060395 SMAD protein signal transduction 7.018727e-6
GO:0015850 organic alcohol transport 7.124288e-6
GO:0016337 cell-cell adhesion 7.293868e-6
GO:0019321 pentose metabolic process 7.741938e-6
GO:0051323 metaphase 7.932825e-6
GO:2000377 regulation of reactive oxygen species metabolic process 7.952223e-6
GO:0051918 negative regulation of fibrinolysis 7.961815e-6
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 8.060054e-6
GO:0042102 positive regulation of T cell proliferation 8.105557e-6
GO:0030187 melatonin biosynthetic process 8.163951e-6
GO:0042424 catecholamine catabolic process 8.181541e-6
GO:0033559 unsaturated fatty acid metabolic process 8.321715e-6
GO:0006702 androgen biosynthetic process 8.444816e-6
GO:0019226 transmission of nerve impulse 9.417965e-6
GO:0010535 positive regulation of activation of JAK2 kinase activity 9.450959e-6
GO:0046649 lymphocyte activation 9.458303e-6
GO:0019752 carboxylic acid metabolic process 9.568269e-6
GO:0006692 prostanoid metabolic process 9.929627e-6
GO:0045056 transcytosis 9.967668e-6
GO:0016101 diterpenoid metabolic process 9.993287e-6
GO:0001666 response to hypoxia 1.026605e-5
GO:0015837 amine transport 1.075393e-5
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 1.104452e-5
GO:0032890 regulation of organic acid transport 1.112230e-5
GO:0006400 tRNA modification 1.153224e-5
GO:0060014 granulosa cell differentiation 1.155611e-5
GO:0046456 icosanoid biosynthetic process 1.170753e-5
GO:0043627 response to estrogen stimulus 1.179948e-5
GO:0016477 cell migration 1.181054e-5
GO:0010873 positive regulation of cholesterol esterification 1.204274e-5
GO:0034382 chylomicron remnant clearance 1.258177e-5
GO:0043032 positive regulation of macrophage activation 1.258304e-5
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 1.264294e-5
GO:0050902 leukocyte adhesive activation 1.264294e-5
GO:0061049 cell growth involved in cardiac muscle cell development 1.289804e-5
GO:0014873 response to muscle activity involved in regulation of muscle adaptation 1.289804e-5
GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure 1.289804e-5
GO:0003331 positive regulation of extracellular matrix constituent secretion 1.289804e-5
GO:0045123 cellular extravasation 1.293349e-5
GO:0007097 nuclear migration 1.321003e-5
GO:0060290 transdifferentiation 1.328809e-5
GO:0002862 negative regulation of inflammatory response to antigenic stimulus 1.332050e-5
GO:0050832 defense response to fungus 1.339779e-5
GO:0002831 regulation of response to biotic stimulus 1.345654e-5
GO:0051291 protein heterooligomerization 1.364039e-5
GO:0050881 musculoskeletal movement 1.372410e-5
GO:0044282 small molecule catabolic process 1.376287e-5
GO:0042035 regulation of cytokine biosynthetic process 1.382830e-5
GO:0001649 osteoblast differentiation 1.393796e-5
GO:0019344 cysteine biosynthetic process 1.394196e-5
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 1.432682e-5
GO:0051917 regulation of fibrinolysis 1.465505e-5
GO:0048535 lymph node development 1.488799e-5
GO:0006693 prostaglandin metabolic process 1.495282e-5
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1.514524e-5
GO:0070932 histone H3 deacetylation 1.586039e-5
GO:0050851 antigen receptor-mediated signaling pathway 1.662255e-5
GO:0002708 positive regulation of lymphocyte mediated immunity 1.692421e-5
GO:0006082 organic acid metabolic process 1.693867e-5
GO:0043252 sodium-independent organic anion transport 1.699774e-5
GO:0002429 immune response-activating cell surface receptor signaling pathway 1.709689e-5
GO:0000089 mitotic metaphase 1.715673e-5
GO:0019693 ribose phosphate metabolic process 1.717695e-5
GO:0042448 progesterone metabolic process 1.736202e-5
GO:0006349 regulation of gene expression by genetic imprinting 1.758872e-5
GO:0032964 collagen biosynthetic process 1.759806e-5
GO:0009199 ribonucleoside triphosphate metabolic process 1.777122e-5
GO:0021623 oculomotor nerve formation 1.823386e-5
GO:0003404 optic vesicle morphogenesis 1.823386e-5
GO:0003409 optic cup structural organization 1.823386e-5
GO:0042573 retinoic acid metabolic process 1.828799e-5
GO:0002885 positive regulation of hypersensitivity 1.865444e-5


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0006952 defense response 1.128060e-21
GO:0023052 signaling 1.977668e-21
GO:0007165 signal transduction 4.294930e-21
GO:0007154 cell communication 2.022038e-20
GO:0050896 response to stimulus 5.244548e-19
GO:0042221 response to chemical stimulus 3.031762e-18
GO:0050776 regulation of immune response 5.574549e-17
GO:0007166 cell surface receptor linked signaling pathway 1.733756e-16
GO:0050727 regulation of inflammatory response 2.003124e-16
GO:0031347 regulation of defense response 2.130019e-16
GO:0009617 response to bacterium 2.205709e-16
GO:0051716 cellular response to stimulus 1.666121e-15
GO:0032101 regulation of response to external stimulus 4.548319e-15
GO:0009607 response to biotic stimulus 1.517895e-14
GO:0006954 inflammatory response 4.575647e-14
GO:0010033 response to organic substance 6.150766e-14
GO:0009628 response to abiotic stimulus 7.438434e-14
GO:0002684 positive regulation of immune system process 8.094378e-14
GO:0032501 multicellular organismal process 1.134411e-13
GO:0032879 regulation of localization 1.137104e-13
GO:0001817 regulation of cytokine production 2.316241e-13
GO:0051707 response to other organism 2.587713e-13
GO:0051049 regulation of transport 3.810588e-13
GO:0002673 regulation of acute inflammatory response 4.393564e-13
GO:0050790 regulation of catalytic activity 7.385831e-13
GO:0048583 regulation of response to stimulus 8.291076e-13
GO:0042742 defense response to bacterium 9.427628e-13
GO:0003008 system process 1.098282e-12
GO:0050778 positive regulation of immune response 2.382143e-12
GO:0009611 response to wounding 4.300054e-12
GO:0007186 G-protein coupled receptor protein signaling pathway 4.692151e-12
GO:0065007 biological regulation 4.776243e-12
GO:0002821 positive regulation of adaptive immune response 7.389781e-12
GO:0051241 negative regulation of multicellular organismal process 1.375285e-11
GO:0043086 negative regulation of catalytic activity 1.497070e-11
GO:0002237 response to molecule of bacterial origin 1.602723e-11
GO:0002718 regulation of cytokine production involved in immune response 1.716747e-11
GO:0045765 regulation of angiogenesis 3.317766e-11
GO:0006955 immune response 3.413609e-11
GO:0006950 response to stress 3.474920e-11
GO:0019882 antigen processing and presentation 5.445082e-11
GO:0051336 regulation of hydrolase activity 9.838035e-11
GO:0032496 response to lipopolysaccharide 1.088081e-10
GO:0065008 regulation of biological quality 1.127193e-10
GO:0055009 atrial cardiac muscle tissue morphogenesis 1.251041e-10
GO:0045833 negative regulation of lipid metabolic process 1.411496e-10
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.504496e-10
GO:0055008 cardiac muscle tissue morphogenesis 2.268387e-10
GO:0002708 positive regulation of lymphocyte mediated immunity 2.942186e-10
GO:0031349 positive regulation of defense response 3.906485e-10
GO:0048002 antigen processing and presentation of peptide antigen 3.969152e-10
GO:0002252 immune effector process 4.470499e-10
GO:0050789 regulation of biological process 5.388063e-10
GO:0032103 positive regulation of response to external stimulus 5.506589e-10
GO:0051704 multi-organism process 6.199741e-10
GO:0071219 cellular response to molecule of bacterial origin 6.264852e-10
GO:0071216 cellular response to biotic stimulus 7.135097e-10
GO:0002682 regulation of immune system process 7.469367e-10
GO:0050708 regulation of protein secretion 1.203222e-9
GO:0002697 regulation of immune effector process 1.332943e-9
GO:0002675 positive regulation of acute inflammatory response 1.532353e-9
GO:0080134 regulation of response to stress 1.557047e-9
GO:0002376 immune system process 1.684785e-9
GO:0070887 cellular response to chemical stimulus 1.765747e-9
GO:0032675 regulation of interleukin-6 production 1.927475e-9
GO:0002819 regulation of adaptive immune response 2.241977e-9
GO:0048585 negative regulation of response to stimulus 2.627943e-9
GO:0002739 regulation of cytokine secretion involved in immune response 2.780244e-9
GO:0014070 response to organic cyclic compound 3.312901e-9
GO:0009125 nucleoside monophosphate catabolic process 3.471176e-9
GO:0002690 positive regulation of leukocyte chemotaxis 5.077127e-9
GO:0002478 antigen processing and presentation of exogenous peptide antigen 6.259340e-9
GO:0051055 negative regulation of lipid biosynthetic process 6.476062e-9
GO:0042993 positive regulation of transcription factor import into nucleus 6.479534e-9
GO:0070201 regulation of establishment of protein localization 6.620089e-9
GO:0003013 circulatory system process 6.933888e-9
GO:0035556 intracellular signal transduction 7.848316e-9
GO:0034382 chylomicron remnant clearance 8.730183e-9
GO:0002687 positive regulation of leukocyte migration 9.650258e-9
GO:0023057 negative regulation of signaling 1.041683e-8
GO:0045321 leukocyte activation 1.163180e-8
GO:0071214 cellular response to abiotic stimulus 1.256903e-8
GO:0065009 regulation of molecular function 1.296484e-8
GO:0001775 cell activation 1.342905e-8
GO:0071310 cellular response to organic substance 1.412588e-8
GO:0042346 positive regulation of NF-kappaB import into nucleus 1.416065e-8
GO:0010574 regulation of vascular endothelial growth factor production 1.416065e-8
GO:0071222 cellular response to lipopolysaccharide 1.606630e-8
GO:0010863 positive regulation of phospholipase C activity 1.760393e-8
GO:0007586 digestion 1.828020e-8
GO:0010648 negative regulation of cell communication 1.954617e-8
GO:0048584 positive regulation of response to stimulus 2.054111e-8
GO:0006198 cAMP catabolic process 2.106358e-8
GO:0009612 response to mechanical stimulus 2.203167e-8
GO:0006810 transport 2.235972e-8
GO:0033344 cholesterol efflux 2.332970e-8
GO:0034762 regulation of transmembrane transport 2.561602e-8
GO:0050794 regulation of cellular process 2.590977e-8
GO:0060415 muscle tissue morphogenesis 2.704033e-8
GO:0051223 regulation of protein transport 2.953349e-8
GO:0051234 establishment of localization 3.127480e-8
GO:0009214 cyclic nucleotide catabolic process 3.768913e-8
GO:0046466 membrane lipid catabolic process 4.286959e-8
GO:0002720 positive regulation of cytokine production involved in immune response 4.523729e-8
GO:0043330 response to exogenous dsRNA 4.915037e-8
GO:0008015 blood circulation 5.364159e-8
GO:0051346 negative regulation of hydrolase activity 5.540014e-8
GO:0042990 regulation of transcription factor import into nucleus 5.647597e-8
GO:0007202 activation of phospholipase C activity 5.917443e-8
GO:0032374 regulation of cholesterol transport 6.038037e-8
GO:0045088 regulation of innate immune response 6.447662e-8
GO:0044092 negative regulation of molecular function 6.487220e-8
GO:0001798 positive regulation of type IIa hypersensitivity 7.119777e-8
GO:0050728 negative regulation of inflammatory response 7.539007e-8
GO:0032488 Cdc42 protein signal transduction 7.775452e-8
GO:0010518 positive regulation of phospholipase activity 7.829421e-8
GO:0002688 regulation of leukocyte chemotaxis 7.904846e-8
GO:0048739 cardiac muscle fiber development 7.960565e-8
GO:0050709 negative regulation of protein secretion 7.977038e-8
GO:0055010 ventricular cardiac muscle tissue morphogenesis 9.227813e-8
GO:0002685 regulation of leukocyte migration 9.577812e-8
GO:0050877 neurological system process 9.618487e-8
GO:0046700 heterocycle catabolic process 9.811070e-8
GO:0002740 negative regulation of cytokine secretion involved in immune response 1.015903e-7
GO:0033700 phospholipid efflux 1.127953e-7
GO:0019884 antigen processing and presentation of exogenous antigen 1.217247e-7
GO:0035335 peptidyl-tyrosine dephosphorylation 1.349278e-7
GO:0051764 actin crosslink formation 1.712444e-7
GO:0009605 response to external stimulus 1.730882e-7
GO:0002027 regulation of heart rate 1.761121e-7
GO:0046649 lymphocyte activation 1.791333e-7
GO:0048519 negative regulation of biological process 1.794307e-7
GO:0002253 activation of immune response 1.893998e-7
GO:0002699 positive regulation of immune effector process 1.925109e-7
GO:0002579 positive regulation of antigen processing and presentation 1.957370e-7
GO:0002700 regulation of production of molecular mediator of immune response 1.967891e-7
GO:0030814 regulation of cAMP metabolic process 2.020810e-7
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.024327e-7
GO:0044270 cellular nitrogen compound catabolic process 2.128718e-7
GO:0002920 regulation of humoral immune response 2.206002e-7
GO:0030817 regulation of cAMP biosynthetic process 2.209649e-7
GO:0007584 response to nutrient 2.346393e-7
GO:0002891 positive regulation of immunoglobulin mediated immune response 2.384687e-7
GO:0010575 positive regulation vascular endothelial growth factor production 2.392706e-7
GO:0051085 chaperone mediated protein folding requiring cofactor 2.658108e-7
GO:0050729 positive regulation of inflammatory response 2.688677e-7
GO:0006659 phosphatidylserine biosynthetic process 2.905525e-7
GO:0008588 release of cytoplasmic sequestered NF-kappaB 2.905525e-7
GO:0050707 regulation of cytokine secretion 2.925386e-7
GO:0032880 regulation of protein localization 3.038816e-7
GO:0003229 ventricular cardiac muscle tissue development 3.289385e-7
GO:0045471 response to ethanol 3.359488e-7
GO:0033275 actin-myosin filament sliding 4.508768e-7
GO:0006200 ATP catabolic process 4.670418e-7
GO:0019376 galactolipid catabolic process 4.685294e-7
GO:0048644 muscle organ morphogenesis 4.778047e-7
GO:0050830 defense response to Gram-positive bacterium 4.827888e-7
GO:0007600 sensory perception 5.001920e-7
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 5.206078e-7
GO:0042345 regulation of NF-kappaB import into nucleus 5.310783e-7
GO:0002366 leukocyte activation involved in immune response 5.314603e-7
GO:0032755 positive regulation of interleukin-6 production 5.394495e-7
GO:0051179 localization 5.480882e-7
GO:0002250 adaptive immune response 5.713104e-7
GO:0055085 transmembrane transport 5.836980e-7
GO:0030799 regulation of cyclic nucleotide metabolic process 5.889611e-7
GO:0009991 response to extracellular stimulus 5.910860e-7
GO:0032375 negative regulation of cholesterol transport 5.987968e-7
GO:0032729 positive regulation of interferon-gamma production 6.011042e-7
GO:0046058 cAMP metabolic process 6.206824e-7
GO:0042493 response to drug 6.266812e-7
GO:0045933 positive regulation of muscle contraction 6.434856e-7
GO:0010954 positive regulation of protein processing 6.716791e-7
GO:0002540 leukotriene production involved in inflammatory response 6.716791e-7
GO:0006690 icosanoid metabolic process 6.977996e-7
GO:0010517 regulation of phospholipase activity 7.067603e-7
GO:0030100 regulation of endocytosis 7.549554e-7
GO:0030819 positive regulation of cAMP biosynthetic process 7.663155e-7
GO:0001819 positive regulation of cytokine production 7.750344e-7
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 8.134274e-7
GO:0045089 positive regulation of innate immune response 8.240497e-7
GO:0016525 negative regulation of angiogenesis 8.246919e-7
GO:0072503 cellular divalent inorganic cation homeostasis 8.515337e-7
GO:0000302 response to reactive oxygen species 8.905581e-7
GO:0006140 regulation of nucleotide metabolic process 9.433703e-7
GO:0052547 regulation of peptidase activity 9.461897e-7
GO:0034097 response to cytokine stimulus 9.995188e-7
GO:0032715 negative regulation of interleukin-6 production 1.067864e-6
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.082856e-6
GO:0009416 response to light stimulus 1.121573e-6
GO:0007522 visceral muscle development 1.134291e-6
GO:0001969 regulation of activation of membrane attack complex 1.189393e-6
GO:0009966 regulation of signal transduction 1.216751e-6
GO:0002885 positive regulation of hypersensitivity 1.337451e-6
GO:0009968 negative regulation of signal transduction 1.348421e-6
GO:0006725 cellular aromatic compound metabolic process 1.384833e-6
GO:0030802 regulation of cyclic nucleotide biosynthetic process 1.430440e-6
GO:0006875 cellular metal ion homeostasis 1.439017e-6
GO:0044130 negative regulation of growth of symbiont in host 1.458915e-6
GO:0031663 lipopolysaccharide-mediated signaling pathway 1.470022e-6
GO:0002218 activation of innate immune response 1.557379e-6
GO:0002285 lymphocyte activation involved in immune response 1.586608e-6
GO:0034764 positive regulation of transmembrane transport 1.586608e-6
GO:0006874 cellular calcium ion homeostasis 1.592107e-6
GO:0071702 organic substance transport 1.704606e-6
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.767181e-6
GO:0031667 response to nutrient levels 1.769422e-6
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 1.873968e-6
GO:0032844 regulation of homeostatic process 1.957089e-6
GO:0002696 positive regulation of leukocyte activation 1.997148e-6
GO:0060555 induction of necroptosis by extracellular signals 2.027229e-6
GO:0051591 response to cAMP 2.045985e-6
GO:0030003 cellular cation homeostasis 2.086436e-6
GO:0023051 regulation of signaling 2.112800e-6
GO:0060191 regulation of lipase activity 2.231946e-6
GO:0010243 response to organic nitrogen 2.244874e-6
GO:0010466 negative regulation of peptidase activity 2.472570e-6
GO:0002861 regulation of inflammatory response to antigenic stimulus 2.510294e-6
GO:0032369 negative regulation of lipid transport 2.584168e-6
GO:0050867 positive regulation of cell activation 2.656922e-6
GO:0040008 regulation of growth 2.760947e-6
GO:0045926 negative regulation of growth 2.788088e-6
GO:0060341 regulation of cellular localization 2.828783e-6
GO:0019374 galactolipid metabolic process 2.878041e-6
GO:0002577 regulation of antigen processing and presentation 2.898451e-6
GO:0072507 divalent inorganic cation homeostasis 2.898466e-6
GO:0032368 regulation of lipid transport 2.988137e-6
GO:0046456 icosanoid biosynthetic process 3.135453e-6
GO:0002827 positive regulation of T-helper 1 type immune response 3.185601e-6
GO:0001970 positive regulation of activation of membrane attack complex 3.305043e-6
GO:0097035 regulation of membrane lipid distribution 3.305043e-6
GO:0050710 negative regulation of cytokine secretion 3.344503e-6
GO:0009719 response to endogenous stimulus 3.447855e-6
GO:0071260 cellular response to mechanical stimulus 3.448008e-6
GO:0045087 innate immune response 3.492326e-6
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 3.521788e-6
GO:0030801 positive regulation of cyclic nucleotide metabolic process 3.530026e-6
GO:0006658 phosphatidylserine metabolic process 3.761419e-6
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 3.872986e-6
GO:0031214 biomineral tissue development 3.907099e-6
GO:0002922 positive regulation of humoral immune response 3.946841e-6
GO:0003209 cardiac atrium morphogenesis 4.144235e-6
GO:0042304 regulation of fatty acid biosynthetic process 4.233019e-6
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 4.243471e-6
GO:0010741 negative regulation of intracellular protein kinase cascade 4.552079e-6
GO:0034655 nucleobase-containing compound catabolic process 4.843484e-6
GO:0051050 positive regulation of transport 4.958334e-6
GO:0050714 positive regulation of protein secretion 5.025046e-6
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 5.403634e-6
GO:0001818 negative regulation of cytokine production 5.454092e-6
GO:0070252 actin-mediated cell contraction 5.537944e-6
GO:0001932 regulation of protein phosphorylation 5.544952e-6
GO:0010985 negative regulation of lipoprotein particle clearance 5.580922e-6
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 5.674878e-6
GO:0015914 phospholipid transport 5.881841e-6
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5.926308e-6
GO:0034380 high-density lipoprotein particle assembly 5.974111e-6
GO:0032692 negative regulation of interleukin-1 production 6.068695e-6
GO:0032642 regulation of chemokine production 6.095977e-6
GO:0010940 positive regulation of necrotic cell death 6.284239e-6
GO:0055074 calcium ion homeostasis 6.462256e-6
GO:0050995 negative regulation of lipid catabolic process 6.466923e-6
GO:0044283 small molecule biosynthetic process 6.687863e-6
GO:0051492 regulation of stress fiber assembly 6.765974e-6
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 6.797283e-6
GO:0045651 positive regulation of macrophage differentiation 6.865497e-6
GO:0001961 positive regulation of cytokine-mediated signaling pathway 6.898150e-6
GO:0043068 positive regulation of programmed cell death 7.206653e-6
GO:0055065 metal ion homeostasis 7.777107e-6
GO:0050870 positive regulation of T cell activation 7.938445e-6
GO:0001558 regulation of cell growth 8.179027e-6
GO:0042306 regulation of protein import into nucleus 8.345134e-6
GO:0002702 positive regulation of production of molecular mediator of immune response 8.462640e-6
GO:0007060 male meiosis chromosome segregation 8.515923e-6
GO:0071496 cellular response to external stimulus 8.576368e-6
GO:0006909 phagocytosis 8.617132e-6
GO:0043065 positive regulation of apoptosis 8.722803e-6
GO:0019932 second-messenger-mediated signaling 8.810236e-6
GO:0042325 regulation of phosphorylation 9.061681e-6
GO:0051128 regulation of cellular component organization 9.156630e-6
GO:0019220 regulation of phosphate metabolic process 9.548984e-6
GO:0010447 response to acidity 9.847116e-6
GO:0051222 positive regulation of protein transport 1.021181e-5
GO:0043462 regulation of ATPase activity 1.030255e-5
GO:0019377 glycolipid catabolic process 1.035281e-5
GO:0006941 striated muscle contraction 1.048899e-5
GO:0051251 positive regulation of lymphocyte activation 1.065078e-5
GO:0002883 regulation of hypersensitivity 1.083134e-5
GO:0060627 regulation of vesicle-mediated transport 1.137023e-5
GO:0008217 regulation of blood pressure 1.144103e-5
GO:0050766 positive regulation of phagocytosis 1.153607e-5
GO:0051046 regulation of secretion 1.162558e-5
GO:0009895 negative regulation of catabolic process 1.164101e-5
GO:0002019 regulation of renal output by angiotensin 1.194461e-5
GO:0045428 regulation of nitric oxide biosynthetic process 1.261478e-5
GO:0055080 cation homeostasis 1.320865e-5
GO:0052548 regulation of endopeptidase activity 1.334310e-5
GO:0060193 positive regulation of lipase activity 1.356143e-5
GO:0010942 positive regulation of cell death 1.372321e-5
GO:0060907 positive regulation of macrophage cytokine production 1.401599e-5
GO:0048731 system development 1.438542e-5
GO:0042307 positive regulation of protein import into nucleus 1.463723e-5
GO:0051480 cytosolic calcium ion homeostasis 1.474882e-5
GO:0031650 regulation of heat generation 1.498400e-5
GO:0045766 positive regulation of angiogenesis 1.525609e-5
GO:0031960 response to corticosteroid stimulus 1.610947e-5
GO:0032691 negative regulation of interleukin-1 beta production 1.624879e-5
GO:0002758 innate immune response-activating signal transduction 1.625383e-5
GO:0051224 negative regulation of protein transport 1.645303e-5
GO:0007623 circadian rhythm 1.656475e-5
GO:0033239 negative regulation of cellular amine metabolic process 1.718630e-5
GO:0071312 cellular response to alkaloid 1.726982e-5
GO:0010646 regulation of cell communication 1.732956e-5
GO:0006811 ion transport 1.752025e-5
GO:0072539 T-helper 17 cell differentiation 1.789783e-5
GO:0051606 detection of stimulus 1.834082e-5
GO:0045717 negative regulation of fatty acid biosynthetic process 1.846258e-5
GO:0032102 negative regulation of response to external stimulus 1.898551e-5
GO:0045429 positive regulation of nitric oxide biosynthetic process 1.905724e-5
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 2.054532e-5
GO:0051345 positive regulation of hydrolase activity 2.094431e-5
GO:0010939 regulation of necrotic cell death 2.102255e-5
GO:0050921 positive regulation of chemotaxis 2.125144e-5
GO:0012502 induction of programmed cell death 2.146742e-5
GO:0046483 heterocycle metabolic process 2.147783e-5
GO:0032649 regulation of interferon-gamma production 2.193843e-5
GO:0046034 ATP metabolic process 2.230808e-5
GO:0032963 collagen metabolic process 2.262208e-5
GO:0051051 negative regulation of transport 2.318576e-5
GO:0007275 multicellular organismal development 2.353577e-5
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 2.408805e-5
GO:0002674 negative regulation of acute inflammatory response 2.447630e-5
GO:0030048 actin filament-based movement 2.451442e-5
GO:0050715 positive regulation of cytokine secretion 2.516489e-5
GO:0009308 amine metabolic process 2.545914e-5
GO:0071321 cellular response to cGMP 2.587606e-5
GO:0006917 induction of apoptosis 2.659567e-5
GO:0048523 negative regulation of cellular process 2.687876e-5
GO:0009314 response to radiation 2.718502e-5
GO:0044062 regulation of excretion 2.729670e-5
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 2.773969e-5
GO:0030804 positive regulation of cyclic nucleotide biosynthetic process 2.854066e-5
GO:0031652 positive regulation of heat generation 2.919960e-5
GO:0030449 regulation of complement activation 2.919960e-5
GO:0016311 dephosphorylation 3.008837e-5
GO:0009894 regulation of catabolic process 3.060942e-5
GO:0070665 positive regulation of leukocyte proliferation 3.075724e-5
GO:0031329 regulation of cellular catabolic process 3.209572e-5
GO:0016064 immunoglobulin mediated immune response 3.225902e-5
GO:0002449 lymphocyte mediated immunity 3.275151e-5
GO:0032946 positive regulation of mononuclear cell proliferation 3.321079e-5
GO:0019724 B cell mediated immunity 3.431207e-5
GO:0051384 response to glucocorticoid stimulus 3.447989e-5
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 3.561759e-5
GO:0006636 unsaturated fatty acid biosynthetic process 3.573423e-5
GO:0006470 protein dephosphorylation 3.618756e-5
GO:0042110 T cell activation 3.669998e-5
GO:0030098 lymphocyte differentiation 3.872666e-5
GO:0048513 organ development 3.873539e-5
GO:0006195 purine nucleotide catabolic process 4.025446e-5
GO:0002521 leukocyte differentiation 4.073400e-5
GO:0048518 positive regulation of biological process 4.099731e-5
GO:0006927 transformed cell apoptosis 4.141621e-5
GO:0002281 macrophage activation involved in immune response 4.236864e-5
GO:0032490 detection of molecule of bacterial origin 4.236864e-5
GO:0051341 regulation of oxidoreductase activity 4.241618e-5
GO:0051445 regulation of meiotic cell cycle 4.514839e-5
GO:0044259 multicellular organismal macromolecule metabolic process 4.615337e-5
GO:0006163 purine nucleotide metabolic process 4.646642e-5
GO:0048016 inositol phosphate-mediated signaling 4.753033e-5
GO:0032930 positive regulation of superoxide anion generation 4.782572e-5
GO:0046942 carboxylic acid transport 4.895457e-5
GO:0032231 regulation of actin filament bundle assembly 5.025238e-5
GO:0045922 negative regulation of fatty acid metabolic process 5.058225e-5
GO:0050953 sensory perception of light stimulus 5.258936e-5
GO:0042592 homeostatic process 5.263654e-5
GO:2000116 regulation of cysteine-type endopeptidase activity 5.328531e-5
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 5.408630e-5
GO:0002706 regulation of lymphocyte mediated immunity 5.441922e-5
GO:0043901 negative regulation of multi-organism process 5.475332e-5
GO:0040020 regulation of meiosis 5.590262e-5
GO:0048878 chemical homeostasis 5.841030e-5
GO:0050865 regulation of cell activation 5.857860e-5
GO:0071827 plasma lipoprotein particle organization 6.032517e-5
GO:0051561 elevation of mitochondrial calcium ion concentration 6.150113e-5
GO:0010873 positive regulation of cholesterol esterification 6.169335e-5
GO:0072523 purine-containing compound catabolic process 6.177259e-5
GO:0032502 developmental process 6.183206e-5
GO:0003230 cardiac atrium development 6.264067e-5
GO:0044255 cellular lipid metabolic process 6.271284e-5
GO:0043434 response to peptide hormone stimulus 6.313929e-5
GO:0050711 negative regulation of interleukin-1 secretion 6.380563e-5
GO:0042488 positive regulation of odontogenesis of dentine-containing tooth 6.558781e-5
GO:0002694 regulation of leukocyte activation 6.617803e-5
GO:0031399 regulation of protein modification process 6.666462e-5
GO:0031348 negative regulation of defense response 6.689719e-5
GO:0006629 lipid metabolic process 6.803012e-5
GO:0002703 regulation of leukocyte mediated immunity 6.874497e-5
GO:0051246 regulation of protein metabolic process 6.924016e-5
GO:0010025 wax biosynthetic process 6.942153e-5
GO:0006958 complement activation, classical pathway 7.100745e-5
GO:0048535 lymph node development 7.214749e-5
GO:0010035 response to inorganic substance 7.607504e-5
GO:0046717 acid secretion 7.768875e-5
GO:0007601 visual perception 7.865519e-5
GO:0006979 response to oxidative stress 7.878875e-5
GO:0009166 nucleotide catabolic process 7.891474e-5
GO:0001890 placenta development 7.946951e-5
GO:0033574 response to testosterone stimulus 8.003056e-5
GO:0045332 phospholipid translocation 8.249085e-5
GO:0003073 regulation of systemic arterial blood pressure 8.342182e-5
GO:0043085 positive regulation of catalytic activity 8.381841e-5
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 8.409682e-5
GO:0070305 response to cGMP 8.480621e-5
GO:0015849 organic acid transport 8.507384e-5
GO:0044057 regulation of system process 8.514752e-5
GO:0009593 detection of chemical stimulus 8.576693e-5
GO:0050671 positive regulation of lymphocyte proliferation 8.588772e-5
GO:0046631 alpha-beta T cell activation 8.607627e-5
GO:0032233 positive regulation of actin filament bundle assembly 8.656527e-5
GO:0010627 regulation of intracellular protein kinase cascade 8.733379e-5
GO:0055114 oxidation-reduction process 8.737084e-5
GO:0070482 response to oxygen levels 8.749933e-5
GO:0031338 regulation of vesicle fusion 8.786735e-5
GO:0019319 hexose biosynthetic process 8.799359e-5
GO:0005976 polysaccharide metabolic process 8.863197e-5
GO:0090209 negative regulation of triglyceride metabolic process 8.894954e-5
GO:0046890 regulation of lipid biosynthetic process 9.182642e-5
GO:0030049 muscle filament sliding 9.488720e-5
GO:0006469 negative regulation of protein kinase activity 9.525522e-5
GO:0007568 aging 9.527887e-5
GO:0034284 response to monosaccharide stimulus 9.643568e-5
GO:0002221 pattern recognition receptor signaling pathway 9.787616e-5
GO:0015909 long-chain fatty acid transport 9.827605e-5
GO:0019725 cellular homeostasis 9.901011e-5
GO:2000379 positive regulation of reactive oxygen species metabolic process 9.958124e-5
GO:0006869 lipid transport 1.010548e-4
GO:0007155 cell adhesion 1.016218e-4
GO:0045080 positive regulation of chemokine biosynthetic process 1.033072e-4
GO:0000185 activation of MAPKKK activity 1.052074e-4
GO:0001702 gastrulation with mouth forming second 1.056734e-4
GO:0001101 response to acid 1.072408e-4
GO:0051348 negative regulation of transferase activity 1.098718e-4
GO:0010984 regulation of lipoprotein particle clearance 1.107538e-4
GO:0006691 leukotriene metabolic process 1.126770e-4
GO:0043407 negative regulation of MAP kinase activity 1.154088e-4
GO:0043154 negative regulation of caspase activity 1.156348e-4
GO:0045071 negative regulation of viral genome replication 1.157486e-4
GO:0048660 regulation of smooth muscle cell proliferation 1.168480e-4
GO:0000188 inactivation of MAPK activity 1.214063e-4
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 1.236952e-4
GO:0051353 positive regulation of oxidoreductase activity 1.239508e-4
GO:0015908 fatty acid transport 1.250163e-4
GO:0033590 response to cobalamin 1.250485e-4
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 1.250485e-4
GO:0002676 regulation of chronic inflammatory response 1.250837e-4
GO:0002757 immune response-activating signal transduction 1.254476e-4
GO:0070508 cholesterol import 1.269825e-4
GO:0032770 positive regulation of monooxygenase activity 1.270348e-4
GO:0022610 biological adhesion 1.312907e-4
GO:0007338 single fertilization 1.317291e-4
GO:0007204 elevation of cytosolic calcium ion concentration 1.336406e-4
GO:0006022 aminoglycan metabolic process 1.387678e-4
GO:0002483 antigen processing and presentation of endogenous peptide antigen 1.394431e-4
GO:0003018 vascular process in circulatory system 1.412430e-4
GO:0002526 acute inflammatory response 1.436614e-4
GO:0045840 positive regulation of mitosis 1.458902e-4
GO:0034447 very-low-density lipoprotein particle clearance 1.472108e-4
GO:0048671 negative regulation of collateral sprouting 1.472582e-4
GO:0006678 glucosylceramide metabolic process 1.472582e-4
GO:0045987 positive regulation of smooth muscle contraction 1.524371e-4
GO:0090023 positive regulation of neutrophil chemotaxis 1.527740e-4
GO:0060760 positive regulation of response to cytokine stimulus 1.530360e-4
GO:0009187 cyclic nucleotide metabolic process 1.542498e-4
GO:0010872 regulation of cholesterol esterification 1.548428e-4
GO:0070555 response to interleukin-1 1.558354e-4
GO:0051053 negative regulation of DNA metabolic process 1.569875e-4
GO:0006812 cation transport 1.595185e-4
GO:0009268 response to pH 1.644421e-4
GO:0048525 negative regulation of viral reproduction 1.671793e-4
GO:0002443 leukocyte mediated immunity 1.675547e-4
GO:0090022 regulation of neutrophil chemotaxis 1.722166e-4
GO:0045746 negative regulation of Notch signaling pathway 1.722166e-4
GO:0060696 regulation of phospholipid catabolic process 1.747512e-4
GO:0016055 Wnt receptor signaling pathway 1.769146e-4
GO:0048856 anatomical structure development 1.772201e-4
GO:0043279 response to alkaloid 1.775614e-4
GO:0061048 negative regulation of branching involved in lung morphogenesis 1.819699e-4
GO:0045994 positive regulation of translational initiation by iron 1.819699e-4
GO:0034116 positive regulation of heterotypic cell-cell adhesion 1.819699e-4
GO:0002037 negative regulation of L-glutamate transport 1.819699e-4
GO:0014075 response to amine stimulus 1.849127e-4
GO:0048738 cardiac muscle tissue development 1.900906e-4
GO:0045948 positive regulation of translational initiation 1.930370e-4
GO:0002724 regulation of T cell cytokine production 1.976812e-4
GO:0050713 negative regulation of interleukin-1 beta secretion 1.998405e-4
GO:0009746 response to hexose stimulus 2.054946e-4
GO:0045851 pH reduction 2.075812e-4
GO:0060338 regulation of type I interferon-mediated signaling pathway 2.110541e-4
GO:0022900 electron transport chain 2.126750e-4