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Novel motif:5

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name:motif5_CAGTGT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0050896 response to stimulus 1.814043e-63
GO:0007154 cell communication 4.636408e-38
GO:0051716 cellular response to stimulus 1.068107e-37
GO:0032501 multicellular organismal process 2.327455e-37
GO:0023052 signaling 5.923166e-36
GO:0007165 signal transduction 2.238033e-34
GO:0042221 response to chemical stimulus 1.295737e-31
GO:0006950 response to stress 1.252895e-29
GO:0002376 immune system process 3.548655e-29
GO:0065008 regulation of biological quality 3.150602e-28
GO:0065007 biological regulation 2.339961e-27
GO:0048731 system development 2.721959e-26
GO:0048583 regulation of response to stimulus 3.098974e-26
GO:0007275 multicellular organismal development 4.659915e-25
GO:0007166 cell surface receptor linked signaling pathway 9.399209e-25
GO:0050789 regulation of biological process 1.872122e-24
GO:0048856 anatomical structure development 9.220623e-24
GO:0032502 developmental process 1.234185e-23
GO:0048513 organ development 1.429874e-23
GO:0050794 regulation of cellular process 1.446890e-23
GO:0007599 hemostasis 3.512400e-23
GO:0007596 blood coagulation 3.897710e-22
GO:0048518 positive regulation of biological process 1.722087e-21
GO:0051179 localization 1.897332e-21
GO:0007155 cell adhesion 2.385915e-21
GO:0042060 wound healing 3.313101e-21
GO:0009611 response to wounding 6.008197e-21
GO:0050878 regulation of body fluid levels 2.055651e-20
GO:0001775 cell activation 4.085209e-20
GO:0006955 immune response 2.420162e-19
GO:0006952 defense response 3.845173e-19
GO:0032879 regulation of localization 5.407646e-19
GO:0016043 cellular component organization 4.566711e-18
GO:0071840 cellular component organization or biogenesis 1.464841e-17
GO:0048584 positive regulation of response to stimulus 2.117043e-17
GO:0050790 regulation of catalytic activity 3.298545e-17
GO:0051239 regulation of multicellular organismal process 4.652585e-17
GO:0023051 regulation of signaling 7.258577e-17
GO:0048522 positive regulation of cellular process 9.530013e-17
GO:0006810 transport 9.700152e-17
GO:0051234 establishment of localization 1.772869e-16
GO:0030334 regulation of cell migration 2.006072e-16
GO:0065009 regulation of molecular function 2.316307e-16
GO:0010646 regulation of cell communication 3.321814e-16
GO:0009607 response to biotic stimulus 4.611095e-16
GO:0040012 regulation of locomotion 5.092791e-16
GO:2000145 regulation of cell motility 2.468381e-15
GO:0009966 regulation of signal transduction 2.915379e-15
GO:0009617 response to bacterium 5.424221e-15
GO:0051707 response to other organism 7.226502e-15
GO:0051270 regulation of cellular component movement 1.178968e-14
GO:0002682 regulation of immune system process 1.836690e-14
GO:0010033 response to organic substance 2.391756e-14
GO:0050793 regulation of developmental process 3.431165e-14
GO:0040011 locomotion 4.148896e-14
GO:0030168 platelet activation 1.846905e-13
GO:0071842 cellular component organization at cellular level 3.556849e-13
GO:0032101 regulation of response to external stimulus 4.034108e-13
GO:0031399 regulation of protein modification process 4.360889e-13
GO:0044093 positive regulation of molecular function 4.751091e-13
GO:0051336 regulation of hydrolase activity 5.256532e-13
GO:0010647 positive regulation of cell communication 1.444091e-12
GO:0048870 cell motility 1.749874e-12
GO:0071841 cellular component organization or biogenesis at cellular level 2.579786e-12
GO:0051246 regulation of protein metabolic process 2.611725e-12
GO:0023056 positive regulation of signaling 2.816944e-12
GO:0030154 cell differentiation 2.991146e-12
GO:0010941 regulation of cell death 4.044076e-12
GO:0042981 regulation of apoptosis 4.411235e-12
GO:0043269 regulation of ion transport 4.641973e-12
GO:0009987 cellular process 5.522636e-12
GO:0070887 cellular response to chemical stimulus 6.247181e-12
GO:2000147 positive regulation of cell motility 6.812566e-12
GO:0030335 positive regulation of cell migration 6.913193e-12
GO:0040017 positive regulation of locomotion 1.113800e-11
GO:0043067 regulation of programmed cell death 1.324462e-11
GO:0032268 regulation of cellular protein metabolic process 1.325237e-11
GO:0002684 positive regulation of immune system process 1.413817e-11
GO:0043412 macromolecule modification 1.901581e-11
GO:0048869 cellular developmental process 2.127014e-11
GO:0019538 protein metabolic process 2.254894e-11
GO:0035556 intracellular signal transduction 2.785954e-11
GO:0006629 lipid metabolic process 2.847137e-11
GO:0050900 leukocyte migration 2.895600e-11
GO:0051272 positive regulation of cellular component movement 2.976039e-11
GO:0019220 regulation of phosphate metabolic process 3.028577e-11
GO:0010035 response to inorganic substance 3.051001e-11
GO:0006464 protein modification process 3.202731e-11
GO:0003008 system process 3.221357e-11
GO:0042325 regulation of phosphorylation 3.424411e-11
GO:0006915 apoptosis 3.682446e-11
GO:0002253 activation of immune response 3.802063e-11
GO:0016477 cell migration 4.265517e-11
GO:0012501 programmed cell death 6.188853e-11
GO:0001819 positive regulation of cytokine production 6.456944e-11
GO:0048519 negative regulation of biological process 7.568600e-11
GO:0006928 cellular component movement 8.099751e-11
GO:0001932 regulation of protein phosphorylation 9.016737e-11
GO:0051704 multi-organism process 9.363168e-11
GO:0043085 positive regulation of catalytic activity 1.369995e-10
GO:0051240 positive regulation of multicellular organismal process 1.439308e-10
GO:0010038 response to metal ion 1.598245e-10
GO:0050778 positive regulation of immune response 1.986707e-10
GO:0001817 regulation of cytokine production 2.241819e-10
GO:0051049 regulation of transport 2.903676e-10
GO:0002443 leukocyte mediated immunity 3.031260e-10
GO:0032496 response to lipopolysaccharide 3.157522e-10
GO:0002237 response to molecule of bacterial origin 3.508036e-10
GO:2000026 regulation of multicellular organismal development 3.609657e-10
GO:0043086 negative regulation of catalytic activity 4.090928e-10
GO:0045785 positive regulation of cell adhesion 4.138582e-10
GO:0006968 cellular defense response 6.538450e-10
GO:0006468 protein phosphorylation 6.563745e-10
GO:0034329 cell junction assembly 6.627682e-10
GO:0001816 cytokine production 8.373348e-10
GO:0044241 lipid digestion 9.595270e-10
GO:0009605 response to external stimulus 1.165260e-9
GO:0030007 cellular potassium ion homeostasis 1.180381e-9
GO:0042742 defense response to bacterium 1.375008e-9
GO:0006725 cellular aromatic compound metabolic process 1.504228e-9
GO:0006684 sphingomyelin metabolic process 1.511555e-9
GO:0009967 positive regulation of signal transduction 1.558992e-9
GO:0007186 G-protein coupled receptor protein signaling pathway 1.674484e-9
GO:0052547 regulation of peptidase activity 1.713954e-9
GO:0060415 muscle tissue morphogenesis 2.000818e-9
GO:0051592 response to calcium ion 2.362896e-9
GO:0030509 BMP signaling pathway 2.508656e-9
GO:0048660 regulation of smooth muscle cell proliferation 2.640267e-9
GO:0006796 phosphate-containing compound metabolic process 2.681721e-9
GO:0032680 regulation of tumor necrosis factor production 2.898950e-9
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 3.034203e-9
GO:0071844 cellular component assembly at cellular level 3.150467e-9
GO:0052548 regulation of endopeptidase activity 3.250166e-9
GO:0006958 complement activation, classical pathway 3.717974e-9
GO:0048523 negative regulation of cellular process 3.809948e-9
GO:0010743 regulation of macrophage derived foam cell differentiation 3.839277e-9
GO:0042592 homeostatic process 5.091208e-9
GO:0009894 regulation of catabolic process 5.415466e-9
GO:0032026 response to magnesium ion 6.155078e-9
GO:0055008 cardiac muscle tissue morphogenesis 6.361761e-9
GO:0010755 regulation of plasminogen activation 7.261046e-9
GO:0071466 cellular response to xenobiotic stimulus 7.278817e-9
GO:0050865 regulation of cell activation 7.764676e-9
GO:0044092 negative regulation of molecular function 7.933918e-9
GO:0051649 establishment of localization in cell 8.426187e-9
GO:0009410 response to xenobiotic stimulus 8.917894e-9
GO:0051222 positive regulation of protein transport 1.184235e-8
GO:0006875 cellular metal ion homeostasis 1.187608e-8
GO:0009888 tissue development 1.296479e-8
GO:0019932 second-messenger-mediated signaling 1.411042e-8
GO:0048585 negative regulation of response to stimulus 1.464172e-8
GO:0009653 anatomical structure morphogenesis 1.535696e-8
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 1.553119e-8
GO:0010466 negative regulation of peptidase activity 1.660989e-8
GO:0006954 inflammatory response 1.701443e-8
GO:0006686 sphingomyelin biosynthetic process 1.894178e-8
GO:0046903 secretion 1.961392e-8
GO:0010757 negative regulation of plasminogen activation 1.961814e-8
GO:0050727 regulation of inflammatory response 2.313907e-8
GO:0021683 cerebellar granular layer morphogenesis 2.415686e-8
GO:0007167 enzyme linked receptor protein signaling pathway 2.477756e-8
GO:0050776 regulation of immune response 2.540034e-8
GO:0060083 smooth muscle contraction involved in micturition 2.596809e-8
GO:0045321 leukocyte activation 3.162514e-8
GO:0048646 anatomical structure formation involved in morphogenesis 3.316057e-8
GO:0048514 blood vessel morphogenesis 3.346110e-8
GO:0045595 regulation of cell differentiation 3.424573e-8
GO:0051128 regulation of cellular component organization 3.572707e-8
GO:0032651 regulation of interleukin-1 beta production 3.664267e-8
GO:0034330 cell junction organization 3.746620e-8
GO:0006811 ion transport 4.162004e-8
GO:0090331 negative regulation of platelet aggregation 4.235024e-8
GO:0061110 dense core granule biogenesis 4.235024e-8
GO:0061108 seminal vesicle epithelium development 4.235024e-8
GO:0042628 mating plug formation 4.235024e-8
GO:0055065 metal ion homeostasis 4.336049e-8
GO:0009191 ribonucleoside diphosphate catabolic process 4.588974e-8
GO:0031581 hemidesmosome assembly 4.843788e-8
GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade 4.893870e-8
GO:0031589 cell-substrate adhesion 5.135525e-8
GO:0051050 positive regulation of transport 5.140321e-8
GO:0072358 cardiovascular system development 5.550745e-8
GO:0032844 regulation of homeostatic process 5.816238e-8
GO:0015872 dopamine transport 5.944000e-8
GO:0051248 negative regulation of protein metabolic process 6.024362e-8
GO:2000021 regulation of ion homeostasis 6.174932e-8
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 6.520547e-8
GO:0006805 xenobiotic metabolic process 6.664947e-8
GO:0030155 regulation of cell adhesion 7.133226e-8
GO:0009820 alkaloid metabolic process 7.164352e-8
GO:0045214 sarcomere organization 7.210597e-8
GO:0032103 positive regulation of response to external stimulus 7.466299e-8
GO:0044057 regulation of system process 7.659299e-8
GO:0006959 humoral immune response 8.055750e-8
GO:0042403 thyroid hormone metabolic process 8.056213e-8
GO:0044267 cellular protein metabolic process 8.234462e-8
GO:0034121 regulation of toll-like receptor signaling pathway 8.561163e-8
GO:0042127 regulation of cell proliferation 8.625445e-8
GO:0050729 positive regulation of inflammatory response 8.828004e-8
GO:0032652 regulation of interleukin-1 production 9.084026e-8
GO:0051094 positive regulation of developmental process 9.335386e-8
GO:0048662 negative regulation of smooth muscle cell proliferation 9.533642e-8
GO:0009449 gamma-aminobutyric acid biosynthetic process 1.005911e-7
GO:0030003 cellular cation homeostasis 1.014460e-7
GO:0051971 positive regulation of transmission of nerve impulse 1.041675e-7
GO:0045794 negative regulation of cell volume 1.079108e-7
GO:0048729 tissue morphogenesis 1.173312e-7
GO:0032989 cellular component morphogenesis 1.181722e-7
GO:0002757 immune response-activating signal transduction 1.196149e-7
GO:0044087 regulation of cellular component biogenesis 1.200077e-7
GO:0072376 protein activation cascade 1.281375e-7
GO:0019933 cAMP-mediated signaling 1.319055e-7
GO:0014832 urinary bladder smooth muscle contraction 1.340369e-7
GO:0046709 IDP catabolic process 1.424009e-7
GO:0046032 ADP catabolic process 1.424009e-7
GO:0045332 phospholipid translocation 1.516083e-7
GO:0031646 positive regulation of neurological system process 1.609925e-7
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 1.626186e-7
GO:0010955 negative regulation of protein processing 1.650044e-7
GO:0051249 regulation of lymphocyte activation 1.693331e-7
GO:0009268 response to pH 1.725712e-7
GO:0002455 humoral immune response mediated by circulating immunoglobulin 1.742745e-7
GO:0042493 response to drug 1.791035e-7
GO:0002694 regulation of leukocyte activation 1.849438e-7
GO:0016310 phosphorylation 1.935849e-7
GO:0050877 neurological system process 1.960429e-7
GO:2000116 regulation of cysteine-type endopeptidase activity 1.962934e-7
GO:0006935 chemotaxis 1.991874e-7
GO:0032836 glomerular basement membrane development 2.014927e-7
GO:0051641 cellular localization 2.109581e-7
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 2.326032e-7
GO:0009181 purine ribonucleoside diphosphate catabolic process 2.379203e-7
GO:0007602 phototransduction 2.394011e-7
GO:0048732 gland development 2.420792e-7
GO:0070373 negative regulation of ERK1 and ERK2 cascade 2.459639e-7
GO:0071310 cellular response to organic substance 2.476720e-7
GO:0051131 chaperone-mediated protein complex assembly 2.478175e-7
GO:0009581 detection of external stimulus 2.490687e-7
GO:0006644 phospholipid metabolic process 2.504548e-7
GO:0046486 glycerolipid metabolic process 2.514586e-7
GO:0021696 cerebellar cortex morphogenesis 2.613757e-7
GO:0007250 activation of NF-kappaB-inducing kinase activity 2.642398e-7
GO:0044255 cellular lipid metabolic process 2.646349e-7
GO:0032940 secretion by cell 2.696842e-7
GO:0030299 intestinal cholesterol absorption 2.841653e-7
GO:0022607 cellular component assembly 3.248227e-7
GO:0061041 regulation of wound healing 3.262156e-7
GO:0002520 immune system development 3.454926e-7
GO:0043065 positive regulation of apoptosis 3.547679e-7
GO:0008219 cell death 3.593606e-7
GO:0051960 regulation of nervous system development 3.707400e-7
GO:0050867 positive regulation of cell activation 3.716660e-7
GO:0006769 nicotinamide metabolic process 3.948162e-7
GO:0009435 NAD biosynthetic process 3.963690e-7
GO:0030036 actin cytoskeleton organization 3.990110e-7
GO:0051338 regulation of transferase activity 4.144899e-7
GO:0070482 response to oxygen levels 4.361810e-7
GO:0071216 cellular response to biotic stimulus 4.534823e-7
GO:0032731 positive regulation of interleukin-1 beta production 4.554287e-7
GO:0055080 cation homeostasis 4.699146e-7
GO:0050663 cytokine secretion 4.704932e-7
GO:0033363 secretory granule organization 4.750862e-7
GO:0002449 lymphocyte mediated immunity 4.869792e-7
GO:0050806 positive regulation of synaptic transmission 4.913233e-7
GO:0019222 regulation of metabolic process 4.948890e-7
GO:0002764 immune response-regulating signaling pathway 5.257975e-7
GO:0050801 ion homeostasis 5.317247e-7
GO:0050851 antigen receptor-mediated signaling pathway 5.318077e-7
GO:0006873 cellular ion homeostasis 5.400454e-7
GO:0071219 cellular response to molecule of bacterial origin 5.553036e-7
GO:0051345 positive regulation of hydrolase activity 5.620933e-7
GO:0007015 actin filament organization 5.773705e-7
GO:0071345 cellular response to cytokine stimulus 6.001285e-7
GO:0010942 positive regulation of cell death 6.346250e-7
GO:0034465 response to carbon monoxide 6.607534e-7
GO:0007417 central nervous system development 6.759914e-7
GO:0060073 micturition 7.372635e-7
GO:0071222 cellular response to lipopolysaccharide 7.515907e-7
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 7.530449e-7
GO:0007160 cell-matrix adhesion 7.654062e-7
GO:0006140 regulation of nucleotide metabolic process 8.286370e-7
GO:0002252 immune effector process 8.427128e-7
GO:0019359 nicotinamide nucleotide biosynthetic process 8.443420e-7
GO:0007267 cell-cell signaling 8.460111e-7
GO:0016265 death 9.008119e-7
GO:0051346 negative regulation of hydrolase activity 9.040272e-7
GO:0010959 regulation of metal ion transport 9.092591e-7
GO:0043068 positive regulation of programmed cell death 9.148586e-7
GO:0048644 muscle organ morphogenesis 9.463452e-7
GO:0071805 potassium ion transmembrane transport 9.590327e-7
GO:0008610 lipid biosynthetic process 1.023573e-6
GO:0008037 cell recognition 1.040816e-6
GO:0051606 detection of stimulus 1.053290e-6
GO:0009719 response to endogenous stimulus 1.110064e-6
GO:0030595 leukocyte chemotaxis 1.113575e-6
GO:0042446 hormone biosynthetic process 1.117662e-6
GO:0007399 nervous system development 1.166112e-6
GO:0040018 positive regulation of multicellular organism growth 1.214213e-6
GO:0044085 cellular component biogenesis 1.256626e-6
GO:0009306 protein secretion 1.270368e-6
GO:0070972 protein localization in endoplasmic reticulum 1.343722e-6
GO:0007243 intracellular protein kinase cascade 1.352168e-6
GO:0007600 sensory perception 1.354031e-6
GO:0032509 endosome transport via multivesicular body sorting pathway 1.379024e-6
GO:0019221 cytokine-mediated signaling pathway 1.382170e-6
GO:0032655 regulation of interleukin-12 production 1.387799e-6
GO:0071954 chemokine (C-C motif) ligand 11 production 1.410996e-6
GO:0035712 T-helper 2 cell activation 1.410996e-6
GO:2000525 positive regulation of T cell costimulation 1.410996e-6
GO:0002215 defense response to nematode 1.410996e-6
GO:0035708 interleukin-4-dependent isotype switching to IgE isotypes 1.410996e-6
GO:0035709 memory T cell activation 1.410996e-6
GO:0033160 positive regulation of protein import into nucleus, translocation 1.419742e-6
GO:0043549 regulation of kinase activity 1.454514e-6
GO:0090361 regulation of platelet-derived growth factor production 1.512789e-6
GO:0019935 cyclic-nucleotide-mediated signaling 1.556755e-6
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 1.613886e-6
GO:0010883 regulation of lipid storage 1.660522e-6
GO:0071360 cellular response to exogenous dsRNA 1.666011e-6
GO:0006228 UTP biosynthetic process 1.666011e-6
GO:0006183 GTP biosynthetic process 1.666011e-6
GO:0006165 nucleoside diphosphate phosphorylation 1.666011e-6
GO:0043687 post-translational protein modification 1.684671e-6
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 1.692984e-6
GO:0032431 activation of phospholipase A2 activity 1.696096e-6
GO:0002832 negative regulation of response to biotic stimulus 1.698652e-6
GO:0042113 B cell activation 1.699628e-6
GO:0032675 regulation of interleukin-6 production 1.712848e-6
GO:0032732 positive regulation of interleukin-1 production 1.742157e-6
GO:0035587 purinergic receptor signaling pathway 1.754506e-6
GO:0032430 positive regulation of phospholipase A2 activity 1.951484e-6
GO:0010627 regulation of intracellular protein kinase cascade 1.995084e-6
GO:0002429 immune response-activating cell surface receptor signaling pathway 2.005860e-6
GO:0030029 actin filament-based process 2.119163e-6
GO:0019725 cellular homeostasis 2.204166e-6
GO:0009615 response to virus 2.208478e-6
GO:0015698 inorganic anion transport 2.212968e-6
GO:0001525 angiogenesis 2.241031e-6
GO:0010888 negative regulation of lipid storage 2.265446e-6
GO:0060326 cell chemotaxis 2.267910e-6
GO:0007044 cell-substrate junction assembly 2.323987e-6
GO:0023057 negative regulation of signaling 2.379864e-6
GO:0050853 B cell receptor signaling pathway 2.439444e-6
GO:0070874 negative regulation of glycogen metabolic process 2.541414e-6
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 2.609078e-6
GO:0002696 positive regulation of leukocyte activation 2.639682e-6
GO:0009628 response to abiotic stimulus 2.713888e-6
GO:0021983 pituitary gland development 2.813698e-6
GO:0006144 purine base metabolic process 2.830346e-6
GO:0051969 regulation of transmission of nerve impulse 2.909207e-6
GO:0060537 muscle tissue development 2.919727e-6
GO:0070613 regulation of protein processing 2.924019e-6
GO:0032269 negative regulation of cellular protein metabolic process 3.053717e-6
GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway 3.059861e-6
GO:0032252 secretory granule localization 3.061555e-6
GO:0010740 positive regulation of intracellular protein kinase cascade 3.088557e-6
GO:0042537 benzene-containing compound metabolic process 3.105830e-6
GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis 3.106250e-6
GO:0048609 multicellular organismal reproductive process 3.177947e-6
GO:0010811 positive regulation of cell-substrate adhesion 3.285481e-6
GO:0010648 negative regulation of cell communication 3.297789e-6
GO:0031057 negative regulation of histone modification 3.390165e-6
GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 3.401545e-6
GO:0010766 negative regulation of sodium ion transport 3.776563e-6
GO:0060795 cell fate commitment involved in formation of primary germ layers 3.801751e-6
GO:0050920 regulation of chemotaxis 3.892691e-6
GO:0051093 negative regulation of developmental process 3.914701e-6
GO:0019674 NAD metabolic process 4.064603e-6
GO:0090116 C-5 methylation of cytosine 4.229023e-6
GO:0006879 cellular iron ion homeostasis 4.350823e-6
GO:0045087 innate immune response 4.398832e-6
GO:0042789 mRNA transcription from RNA polymerase II promoter 4.462788e-6
GO:0009156 ribonucleoside monophosphate biosynthetic process 4.465187e-6
GO:0007194 negative regulation of adenylate cyclase activity 4.658238e-6
GO:0019724 B cell mediated immunity 4.859934e-6
GO:0001568 blood vessel development 4.904714e-6
GO:0030814 regulation of cAMP metabolic process 4.948433e-6
GO:0046498 S-adenosylhomocysteine metabolic process 4.950659e-6
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 5.005526e-6
GO:0006956 complement activation 5.252475e-6
GO:0032776 DNA methylation on cytosine 5.396157e-6
GO:0032735 positive regulation of interleukin-12 production 5.441388e-6
GO:0010869 regulation of receptor biosynthetic process 5.508814e-6
GO:0030097 hemopoiesis 5.529709e-6
GO:0033993 response to lipid 5.621464e-6
GO:0048878 chemical homeostasis 5.653298e-6
GO:0045165 cell fate commitment 5.671487e-6
GO:0031400 negative regulation of protein modification process 5.861566e-6
GO:0016064 immunoglobulin mediated immune response 6.187167e-6
GO:0048738 cardiac muscle tissue development 6.188953e-6
GO:0043502 regulation of muscle adaptation 6.313662e-6
GO:0003013 circulatory system process 6.361678e-6
GO:0046131 pyrimidine ribonucleoside metabolic process 6.374145e-6
GO:0048468 cell development 6.412135e-6
GO:0018958 phenol-containing compound metabolic process 6.526155e-6
GO:0030183 B cell differentiation 6.552528e-6
GO:0046467 membrane lipid biosynthetic process 6.653898e-6
GO:0006590 thyroid hormone generation 6.660907e-6
GO:0045666 positive regulation of neuron differentiation 7.148182e-6
GO:0040007 growth 7.190945e-6
GO:0043154 negative regulation of caspase activity 7.273177e-6
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 7.375919e-6
GO:0040013 negative regulation of locomotion 7.382718e-6
GO:0051350 negative regulation of lyase activity 7.543054e-6
GO:0030035 microspike assembly 7.833049e-6
GO:0000902 cell morphogenesis 7.978897e-6
GO:0007420 brain development 8.072887e-6
GO:0043434 response to peptide hormone stimulus 8.179948e-6
GO:0048009 insulin-like growth factor receptor signaling pathway 8.217153e-6
GO:0007517 muscle organ development 8.232226e-6
GO:0002768 immune response-regulating cell surface receptor signaling pathway 8.366819e-6
GO:0090291 negative regulation of osteoclast proliferation 8.555318e-6
GO:2000347 positive regulation of hepatocyte proliferation 8.555318e-6
GO:0072573 tolerance induction to lipopolysaccharide 8.555318e-6
GO:2000349 negative regulation of CD40 signaling pathway 8.555318e-6
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 8.555318e-6
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 8.555318e-6
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 8.555318e-6
GO:0048534 hemopoietic or lymphoid organ development 8.746138e-6
GO:0055010 ventricular cardiac muscle tissue morphogenesis 8.836307e-6
GO:0030817 regulation of cAMP biosynthetic process 8.987423e-6
GO:0031644 regulation of neurological system process 9.450781e-6
GO:0014848 urinary tract smooth muscle contraction 9.535323e-6
GO:0035270 endocrine system development 9.606140e-6
GO:0009167 purine ribonucleoside monophosphate metabolic process 9.965164e-6
GO:0021854 hypothalamus development 1.005388e-5
GO:0009968 negative regulation of signal transduction 1.009531e-5
GO:0021681 cerebellar granular layer development 1.053103e-5
GO:0019226 transmission of nerve impulse 1.067140e-5
GO:0045859 regulation of protein kinase activity 1.106887e-5
GO:0045637 regulation of myeloid cell differentiation 1.118155e-5
GO:0050869 negative regulation of B cell activation 1.138495e-5
GO:0006241 CTP biosynthetic process 1.181882e-5
GO:0080134 regulation of response to stress 1.191716e-5
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 1.203598e-5
GO:0032463 negative regulation of protein homooligomerization 1.208408e-5
GO:0001944 vasculature development 1.228761e-5
GO:0009112 nucleobase metabolic process 1.239274e-5
GO:0003229 ventricular cardiac muscle tissue development 1.247879e-5
GO:0045719 negative regulation of glycogen biosynthetic process 1.303064e-5
GO:0007268 synaptic transmission 1.310882e-5
GO:0045596 negative regulation of cell differentiation 1.344256e-5
GO:0010745 negative regulation of macrophage derived foam cell differentiation 1.378997e-5
GO:0060600 dichotomous subdivision of an epithelial terminal unit 1.384685e-5
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 1.418056e-5
GO:0055082 cellular chemical homeostasis 1.422182e-5
GO:0044238 primary metabolic process 1.428230e-5
GO:0010810 regulation of cell-substrate adhesion 1.449476e-5
GO:0045124 regulation of bone resorption 1.452716e-5
GO:0019637 organophosphate metabolic process 1.456980e-5
GO:0040008 regulation of growth 1.492793e-5
GO:0035590 purinergic nucleotide receptor signaling pathway 1.501480e-5
GO:0006704 glucocorticoid biosynthetic process 1.545331e-5
GO:0046847 filopodium assembly 1.545558e-5
GO:0045056 transcytosis 1.547332e-5
GO:0010614 negative regulation of cardiac muscle hypertrophy 1.592659e-5
GO:0009161 ribonucleoside monophosphate metabolic process 1.604337e-5
GO:0008015 blood circulation 1.613153e-5
GO:0051937 catecholamine transport 1.639569e-5
GO:0051241 negative regulation of multicellular organismal process 1.744657e-5
GO:0071634 regulation of transforming growth factor beta production 1.771572e-5
GO:0055015 ventricular cardiac muscle cell development 1.797044e-5
GO:0007588 excretion 1.863804e-5
GO:0016192 vesicle-mediated transport 1.869037e-5
GO:0010524 positive regulation of calcium ion transport into cytosol 1.901545e-5
GO:0016044 cellular membrane organization 1.959990e-5
GO:0051788 response to misfolded protein 1.962144e-5
GO:0032755 positive regulation of interleukin-6 production 1.967508e-5
GO:0046649 lymphocyte activation 1.976044e-5
GO:0006812 cation transport 1.984311e-5
GO:0009880 embryonic pattern specification 1.987544e-5
GO:0032102 negative regulation of response to external stimulus 2.024714e-5
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 2.034916e-5
GO:0034762 regulation of transmembrane transport 2.120271e-5
GO:0030030 cell projection organization 2.130299e-5
GO:0055009 atrial cardiac muscle tissue morphogenesis 2.170914e-5
GO:0031032 actomyosin structure organization 2.201941e-5
GO:0000904 cell morphogenesis involved in differentiation 2.244829e-5
GO:0080090 regulation of primary metabolic process 2.253334e-5
GO:0030239 myofibril assembly 2.265797e-5
GO:0034123 positive regulation of toll-like receptor signaling pathway 2.293067e-5
GO:0001666 response to hypoxia 2.446887e-5
GO:0061024 membrane organization 2.460859e-5
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 2.529476e-5
GO:0045765 regulation of angiogenesis 2.540070e-5
GO:0002446 neutrophil mediated immunity 2.650284e-5
GO:0010677 negative regulation of cellular carbohydrate metabolic process 2.695011e-5
GO:0014706 striated muscle tissue development 2.894171e-5
GO:0050852 T cell receptor signaling pathway 2.922231e-5
GO:0050864 regulation of B cell activation 2.955007e-5
GO:0097035 regulation of membrane lipid distribution 2.964128e-5
GO:0048596 embryonic camera-type eye morphogenesis 2.967838e-5
GO:0009582 detection of abiotic stimulus 2.971276e-5
GO:0007162 negative regulation of cell adhesion 2.995066e-5
GO:0000165 MAPKKK cascade 3.144456e-5
GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity 3.197442e-5
GO:0009896 positive regulation of catabolic process 3.212515e-5
GO:0060402 calcium ion transport into cytosol 3.258147e-5
GO:0033121 regulation of purine nucleotide catabolic process 3.270153e-5
GO:0050771 negative regulation of axonogenesis 3.297066e-5


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0006952 defense response 2.421913e-22
GO:0050896 response to stimulus 4.041977e-17
GO:0006953 acute-phase response 4.818643e-17
GO:0006954 inflammatory response 5.478882e-17
GO:0030488 tRNA methylation 7.492852e-17
GO:0002526 acute inflammatory response 3.557300e-16
GO:0002376 immune system process 4.646896e-15
GO:0031347 regulation of defense response 2.137543e-14
GO:0050727 regulation of inflammatory response 3.989350e-13
GO:0006810 transport 5.476544e-13
GO:0051234 establishment of localization 8.971222e-13
GO:0032101 regulation of response to external stimulus 2.106576e-12
GO:0009611 response to wounding 3.045614e-12
GO:0002684 positive regulation of immune system process 5.918266e-12
GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis 7.102654e-12
GO:0030502 negative regulation of bone mineralization 1.239297e-11
GO:0030157 pancreatic juice secretion 1.722668e-11
GO:0001817 regulation of cytokine production 1.876661e-11
GO:0045780 positive regulation of bone resorption 2.010632e-11
GO:0021987 cerebral cortex development 2.850901e-11
GO:0070168 negative regulation of biomineral tissue development 3.039814e-11
GO:0051179 localization 3.481377e-11
GO:0006950 response to stress 6.198257e-11
GO:0046466 membrane lipid catabolic process 7.091018e-11
GO:0034097 response to cytokine stimulus 7.156340e-11
GO:0042221 response to chemical stimulus 7.648311e-11
GO:0030149 sphingolipid catabolic process 8.760356e-11
GO:0045124 regulation of bone resorption 1.200740e-10
GO:0046627 negative regulation of insulin receptor signaling pathway 1.335561e-10
GO:0009617 response to bacterium 1.685766e-10
GO:0016192 vesicle-mediated transport 1.993061e-10
GO:0071345 cellular response to cytokine stimulus 3.089335e-10
GO:0044242 cellular lipid catabolic process 3.434642e-10
GO:0002682 regulation of immune system process 4.013654e-10
GO:0045807 positive regulation of endocytosis 4.662456e-10
GO:0008033 tRNA processing 7.139225e-10
GO:0032846 positive regulation of homeostatic process 1.211684e-9
GO:0006507 GPI anchor release 1.423442e-9
GO:0050766 positive regulation of phagocytosis 2.826442e-9
GO:0042742 defense response to bacterium 3.775688e-9
GO:0046850 regulation of bone remodeling 5.655093e-9
GO:0007050 cell cycle arrest 7.167826e-9
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 7.371268e-9
GO:0009607 response to biotic stimulus 7.384314e-9
GO:0001819 positive regulation of cytokine production 7.878907e-9
GO:0034105 positive regulation of tissue remodeling 1.252977e-8
GO:0006400 tRNA modification 1.544006e-8
GO:0051249 regulation of lymphocyte activation 1.742319e-8
GO:0042269 regulation of natural killer cell mediated cytotoxicity 1.868252e-8
GO:0065008 regulation of biological quality 1.899858e-8
GO:0044281 small molecule metabolic process 1.954736e-8
GO:0051707 response to other organism 2.041075e-8
GO:0080134 regulation of response to stress 2.063406e-8
GO:0050776 regulation of immune response 2.292193e-8
GO:0032501 multicellular organismal process 2.321767e-8
GO:0034391 regulation of smooth muscle cell apoptosis 3.923975e-8
GO:0006955 immune response 3.967808e-8
GO:0006399 tRNA metabolic process 5.247929e-8
GO:0060509 Type I pneumocyte differentiation 5.605307e-8
GO:0051704 multi-organism process 6.345552e-8
GO:0050863 regulation of T cell activation 7.062818e-8
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 7.230121e-8
GO:0006110 regulation of glycolysis 8.275198e-8
GO:0040011 locomotion 8.888130e-8
GO:0046514 ceramide catabolic process 1.118363e-7
GO:0010743 regulation of macrophage derived foam cell differentiation 1.318025e-7
GO:0051050 positive regulation of transport 1.634370e-7
GO:0032663 regulation of interleukin-2 production 1.897050e-7
GO:0046626 regulation of insulin receptor signaling pathway 2.070675e-7
GO:0002694 regulation of leukocyte activation 2.338950e-7
GO:0051240 positive regulation of multicellular organismal process 2.398980e-7
GO:0030001 metal ion transport 2.749317e-7
GO:0035630 bone mineralization involved in bone maturation 2.857029e-7
GO:0045088 regulation of innate immune response 2.930223e-7
GO:0050764 regulation of phagocytosis 2.965231e-7
GO:0044341 sodium-dependent phosphate transport 3.406175e-7
GO:0048583 regulation of response to stimulus 3.493964e-7
GO:0006811 ion transport 3.526615e-7
GO:0045786 negative regulation of cell cycle 3.622381e-7
GO:0050865 regulation of cell activation 3.784971e-7
GO:0006812 cation transport 3.816778e-7
GO:0032102 negative regulation of response to external stimulus 4.031662e-7
GO:0048193 Golgi vesicle transport 4.771281e-7
GO:0050778 positive regulation of immune response 4.843118e-7
GO:0051716 cellular response to stimulus 6.183591e-7
GO:0034103 regulation of tissue remodeling 6.878240e-7
GO:0097035 regulation of membrane lipid distribution 6.887204e-7
GO:0010906 regulation of glucose metabolic process 7.324276e-7
GO:0008045 motor axon guidance 7.959000e-7
GO:0019752 carboxylic acid metabolic process 8.068602e-7
GO:0010827 regulation of glucose transport 8.488246e-7
GO:0043931 ossification involved in bone maturation 9.376300e-7
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 9.727143e-7
GO:0060510 Type II pneumocyte differentiation 9.946467e-7
GO:0006518 peptide metabolic process 9.954705e-7
GO:0009056 catabolic process 1.069135e-6
GO:0016042 lipid catabolic process 1.135352e-6
GO:0001887 selenium compound metabolic process 1.239304e-6
GO:0014706 striated muscle tissue development 1.241562e-6
GO:0010575 positive regulation vascular endothelial growth factor production 1.247954e-6
GO:0048513 organ development 1.254989e-6
GO:0046903 secretion 1.282181e-6
GO:0006082 organic acid metabolic process 1.291651e-6
GO:0042180 cellular ketone metabolic process 1.438855e-6
GO:0021543 pallium development 1.460334e-6
GO:0045329 carnitine biosynthetic process 1.634052e-6
GO:0048660 regulation of smooth muscle cell proliferation 1.804492e-6
GO:0009791 post-embryonic development 1.847059e-6
GO:0000003 reproduction 1.857321e-6
GO:0006749 glutathione metabolic process 1.923656e-6
GO:0070977 bone maturation 1.941054e-6
GO:0009451 RNA modification 2.022508e-6
GO:0050870 positive regulation of T cell activation 2.035655e-6
GO:0021960 anterior commissure morphogenesis 2.038453e-6
GO:0031349 positive regulation of defense response 2.070181e-6
GO:0010033 response to organic substance 2.254588e-6
GO:0006678 glucosylceramide metabolic process 2.284004e-6
GO:0007186 G-protein coupled receptor protein signaling pathway 2.374167e-6
GO:0031348 negative regulation of defense response 2.391955e-6
GO:0030154 cell differentiation 2.504915e-6
GO:0014904 myotube cell development 2.576338e-6
GO:0060537 muscle tissue development 2.588180e-6
GO:0002706 regulation of lymphocyte mediated immunity 2.667902e-6
GO:0042592 homeostatic process 2.732779e-6
GO:0032844 regulation of homeostatic process 2.735369e-6
GO:0006813 potassium ion transport 2.864949e-6
GO:0021799 cerebral cortex radially oriented cell migration 2.963539e-6
GO:0007010 cytoskeleton organization 2.997863e-6
GO:0050901 leukocyte tethering or rolling 3.038597e-6
GO:0048585 negative regulation of response to stimulus 3.300951e-6
GO:0001910 regulation of leukocyte mediated cytotoxicity 3.313007e-6
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 3.369525e-6
GO:0010269 response to selenium ion 3.626165e-6
GO:0055114 oxidation-reduction process 4.077208e-6
GO:0019722 calcium-mediated signaling 4.186519e-6
GO:0031341 regulation of cell killing 4.400456e-6
GO:0010744 positive regulation of macrophage derived foam cell differentiation 4.940850e-6
GO:0006968 cellular defense response 5.075743e-6
GO:0048240 sperm capacitation 5.227123e-6
GO:0046324 regulation of glucose import 5.309397e-6
GO:0044248 cellular catabolic process 5.381994e-6
GO:0007165 signal transduction 5.482316e-6
GO:0048869 cellular developmental process 5.521199e-6
GO:0045089 positive regulation of innate immune response 5.621166e-6
GO:0051649 establishment of localization in cell 6.035406e-6
GO:0065007 biological regulation 6.208586e-6
GO:0051251 positive regulation of lymphocyte activation 6.651546e-6
GO:0051241 negative regulation of multicellular organismal process 6.913873e-6
GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 6.952114e-6
GO:0009605 response to external stimulus 7.582009e-6
GO:0014894 response to denervation involved in regulation of muscle adaptation 7.739251e-6
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 8.384767e-6
GO:0034114 regulation of heterotypic cell-cell adhesion 8.384767e-6
GO:0016074 snoRNA metabolic process 8.423291e-6
GO:0034383 low-density lipoprotein particle clearance 8.918775e-6
GO:0032649 regulation of interferon-gamma production 8.951417e-6
GO:0030029 actin filament-based process 9.063085e-6
GO:0002673 regulation of acute inflammatory response 9.333556e-6
GO:0046032 ADP catabolic process 9.477534e-6
GO:0046709 IDP catabolic process 9.477534e-6
GO:0044282 small molecule catabolic process 9.507120e-6
GO:0072329 monocarboxylic acid catabolic process 9.522490e-6
GO:0009750 response to fructose stimulus 9.772235e-6
GO:0032879 regulation of localization 9.883701e-6
GO:0032655 regulation of interleukin-12 production 1.014317e-5
GO:0022414 reproductive process 1.108890e-5
GO:0021537 telencephalon development 1.111955e-5
GO:0044255 cellular lipid metabolic process 1.166564e-5
GO:0009062 fatty acid catabolic process 1.216160e-5
GO:0010675 regulation of cellular carbohydrate metabolic process 1.222096e-5
GO:0045076 regulation of interleukin-2 biosynthetic process 1.266403e-5
GO:0001660 fever generation 1.270547e-5
GO:0033152 immunoglobulin V(D)J recombination 1.283381e-5
GO:0032502 developmental process 1.292872e-5
GO:0048305 immunoglobulin secretion 1.383693e-5
GO:0003006 developmental process involved in reproduction 1.403979e-5
GO:0006629 lipid metabolic process 1.410842e-5
GO:0007154 cell communication 1.438954e-5
GO:0034392 negative regulation of smooth muscle cell apoptosis 1.449326e-5
GO:0010574 regulation of vascular endothelial growth factor production 1.539160e-5
GO:0031032 actomyosin structure organization 1.539709e-5
GO:0060741 prostate gland stromal morphogenesis 1.545878e-5
GO:0000212 meiotic spindle organization 1.545878e-5
GO:0007565 female pregnancy 1.555734e-5
GO:0006109 regulation of carbohydrate metabolic process 1.580654e-5
GO:0006725 cellular aromatic compound metabolic process 1.596919e-5
GO:0050867 positive regulation of cell activation 1.662327e-5
GO:0032729 positive regulation of interferon-gamma production 1.664733e-5
GO:0048009 insulin-like growth factor receptor signaling pathway 1.736664e-5
GO:0048518 positive regulation of biological process 1.783276e-5
GO:0045907 positive regulation of vasoconstriction 2.105456e-5
GO:0009306 protein secretion 2.116235e-5
GO:0046425 regulation of JAK-STAT cascade 2.127986e-5
GO:0000038 very long-chain fatty acid metabolic process 2.142196e-5
GO:0002237 response to molecule of bacterial origin 2.217632e-5
GO:0032940 secretion by cell 2.233622e-5
GO:0008203 cholesterol metabolic process 2.236089e-5
GO:0023052 signaling 2.303387e-5
GO:0010886 positive regulation of cholesterol storage 2.327291e-5
GO:0051239 regulation of multicellular organismal process 2.393622e-5
GO:0030036 actin cytoskeleton organization 2.424187e-5
GO:0030100 regulation of endocytosis 2.441027e-5
GO:0030239 myofibril assembly 2.613211e-5
GO:0001818 negative regulation of cytokine production 2.715280e-5
GO:0046395 carboxylic acid catabolic process 2.797484e-5
GO:0050810 regulation of steroid biosynthetic process 2.839402e-5
GO:0042953 lipoprotein transport 2.846807e-5
GO:0043043 peptide biosynthetic process 2.863584e-5
GO:0050830 defense response to Gram-positive bacterium 2.896488e-5
GO:0010828 positive regulation of glucose transport 2.902907e-5
GO:0034766 negative regulation of ion transmembrane transport 2.988134e-5
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 2.988134e-5
GO:0021758 putamen development 2.988134e-5
GO:0021757 caudate nucleus development 2.988134e-5
GO:0017121 phospholipid scrambling 2.988134e-5
GO:0021615 glossopharyngeal nerve morphogenesis 2.988134e-5
GO:0042035 regulation of cytokine biosynthetic process 3.081201e-5
GO:0007166 cell surface receptor linked signaling pathway 3.188020e-5
GO:0006787 porphyrin-containing compound catabolic process 3.448410e-5
GO:0006928 cellular component movement 3.457987e-5
GO:0006707 cholesterol catabolic process 3.480925e-5
GO:0002703 regulation of leukocyte mediated immunity 3.563380e-5
GO:0030900 forebrain development 3.605248e-5
GO:0043467 regulation of generation of precursor metabolites and energy 3.619836e-5
GO:0002696 positive regulation of leukocyte activation 3.685693e-5
GO:0030279 negative regulation of ossification 3.885604e-5
GO:0010464 regulation of mesenchymal cell proliferation 4.074130e-5
GO:0032496 response to lipopolysaccharide 4.397541e-5
GO:0006089 lactate metabolic process 4.453833e-5
GO:0045086 positive regulation of interleukin-2 biosynthetic process 4.459483e-5
GO:0070887 cellular response to chemical stimulus 4.530549e-5
GO:0048584 positive regulation of response to stimulus 4.574235e-5
GO:0048662 negative regulation of smooth muscle cell proliferation 4.579248e-5
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 4.694681e-5
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 4.767520e-5
GO:0016044 cellular membrane organization 4.811857e-5
GO:0006892 post-Golgi vesicle-mediated transport 4.951370e-5
GO:0032787 monocarboxylic acid metabolic process 5.166087e-5
GO:0016554 cytidine to uridine editing 5.244725e-5
GO:0035556 intracellular signal transduction 5.296190e-5
GO:0010042 response to manganese ion 5.370067e-5
GO:0042346 positive regulation of NF-kappaB import into nucleus 5.476424e-5
GO:0002675 positive regulation of acute inflammatory response 5.642407e-5
GO:0070373 negative regulation of ERK1 and ERK2 cascade 5.642407e-5
GO:0030258 lipid modification 5.692262e-5
GO:0002708 positive regulation of lymphocyte mediated immunity 5.710623e-5
GO:0032869 cellular response to insulin stimulus 5.769376e-5
GO:0070741 response to interleukin-6 5.853794e-5
GO:0031343 positive regulation of cell killing 6.054349e-5
GO:0061024 membrane organization 6.157894e-5
GO:0045821 positive regulation of glycolysis 6.264569e-5
GO:0050728 negative regulation of inflammatory response 6.545311e-5
GO:0022610 biological adhesion 6.603925e-5
GO:0032653 regulation of interleukin-10 production 6.654592e-5
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 7.318446e-5
GO:0032868 response to insulin stimulus 7.574712e-5
GO:0051260 protein homooligomerization 7.665413e-5
GO:0032703 negative regulation of interleukin-2 production 7.994819e-5
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 8.543639e-5
GO:0006959 humoral immune response 8.571372e-5
GO:0002318 myeloid progenitor cell differentiation 8.581593e-5
GO:0045540 regulation of cholesterol biosynthetic process 8.587494e-5
GO:0046459 short-chain fatty acid metabolic process 8.644731e-5
GO:0002377 immunoglobulin production 8.768346e-5
GO:0032753 positive regulation of interleukin-4 production 8.868755e-5
GO:0051056 regulation of small GTPase mediated signal transduction 8.909462e-5
GO:0048738 cardiac muscle tissue development 8.997136e-5
GO:0010885 regulation of cholesterol storage 9.346304e-5
GO:0019221 cytokine-mediated signaling pathway 9.353249e-5
GO:0006508 proteolysis 9.946701e-5
GO:0006750 glutathione biosynthetic process 9.963846e-5
GO:0001510 RNA methylation 1.010327e-4
GO:0046326 positive regulation of glucose import 1.012907e-4
GO:0000041 transition metal ion transport 1.025335e-4
GO:0007155 cell adhesion 1.035331e-4
GO:0010741 negative regulation of intracellular protein kinase cascade 1.039588e-4
GO:0043471 regulation of cellular carbohydrate catabolic process 1.050428e-4
GO:0060948 cardiac vascular smooth muscle cell development 1.059627e-4
GO:0031295 T cell costimulation 1.100295e-4
GO:0031622 positive regulation of fever generation 1.115870e-4
GO:0048856 anatomical structure development 1.233639e-4
GO:0060479 lung cell differentiation 1.252200e-4
GO:0060486 Clara cell differentiation 1.280568e-4
GO:0002699 positive regulation of immune effector process 1.357677e-4
GO:0048870 cell motility 1.363038e-4
GO:0048840 otolith development 1.385800e-4
GO:0045321 leukocyte activation 1.396186e-4
GO:0021559 trigeminal nerve development 1.424407e-4
GO:0050789 regulation of biological process 1.458487e-4
GO:0045428 regulation of nitric oxide biosynthetic process 1.473776e-4
GO:0009308 amine metabolic process 1.500160e-4
GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 1.546070e-4
GO:0006520 cellular amino acid metabolic process 1.627768e-4
GO:0010660 regulation of muscle cell apoptosis 1.634269e-4
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 1.656679e-4
GO:0022406 membrane docking 1.658265e-4
GO:0002252 immune effector process 1.683329e-4
GO:0051262 protein tetramerization 1.696101e-4
GO:0031620 regulation of fever generation 1.729930e-4
GO:0060487 lung epithelial cell differentiation 1.734760e-4
GO:0012501 programmed cell death 1.744735e-4
GO:0019371 cyclooxygenase pathway 1.779943e-4
GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis 1.813199e-4
GO:2000791 negative regulation of mesenchymal cell proliferation involved in lung development 1.813199e-4
GO:0061141 lung ciliated cell differentiation 1.813199e-4
GO:0021740 principal sensory nucleus of trigeminal nerve development 1.813199e-4
GO:0051049 regulation of transport 1.817368e-4
GO:0048015 phosphatidylinositol-mediated signaling 1.870734e-4
GO:0070633 transepithelial transport 1.928074e-4
GO:0010951 negative regulation of endopeptidase activity 1.946517e-4
GO:0032108 negative regulation of response to nutrient levels 2.058940e-4
GO:0071356 cellular response to tumor necrosis factor 2.090935e-4
GO:0060992 response to fungicide 2.100005e-4
GO:0006893 Golgi to plasma membrane transport 2.110388e-4
GO:0042127 regulation of cell proliferation 2.139144e-4
GO:0090181 regulation of cholesterol metabolic process 2.150666e-4
GO:0035690 cellular response to drug 2.322415e-4
GO:0050900 leukocyte migration 2.383458e-4
GO:0006422 aspartyl-tRNA aminoacylation 2.434569e-4
GO:0003029 detection of hypoxic conditions in blood by carotid body chemoreceptor signaling 2.492824e-4
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 2.516881e-4
GO:0009991 response to extracellular stimulus 2.517141e-4
GO:0002248 connective tissue replacement involved in inflammatory response wound healing 2.544698e-4
GO:0042421 norepinephrine biosynthetic process 2.564250e-4
GO:0010627 regulation of intracellular protein kinase cascade 2.692058e-4
GO:0019374 galactolipid metabolic process 2.702813e-4
GO:0046578 regulation of Ras protein signal transduction 2.724537e-4
GO:0033273 response to vitamin 2.749141e-4
GO:0030282 bone mineralization 2.757249e-4
GO:0006904 vesicle docking involved in exocytosis 2.809490e-4
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 2.813455e-4
GO:0033197 response to vitamin E 2.821742e-4
GO:0010661 positive regulation of muscle cell apoptosis 2.832932e-4
GO:0006583 melanin biosynthetic process from tyrosine 2.836437e-4
GO:0006575 cellular modified amino acid metabolic process 2.846628e-4
GO:0021602 cranial nerve morphogenesis 2.849699e-4
GO:0032814 regulation of natural killer cell activation 2.938093e-4
GO:0032944 regulation of mononuclear cell proliferation 2.946228e-4
GO:0032107 regulation of response to nutrient levels 2.970824e-4
GO:0010912 positive regulation of isomerase activity 3.051872e-4
GO:0023021 termination of signal transduction 3.098544e-4
GO:0016125 sterol metabolic process 3.160489e-4
GO:0006935 chemotaxis 3.182549e-4
GO:0042993 positive regulation of transcription factor import into nucleus 3.225299e-4
GO:0009566 fertilization 3.226293e-4
GO:0051454 intracellular pH elevation 3.297246e-4
GO:0021636 trigeminal nerve morphogenesis 3.303277e-4
GO:0003348 cardiac endothelial cell differentiation 3.303277e-4
GO:0031667 response to nutrient levels 3.371195e-4
GO:0010459 negative regulation of heart rate 3.375682e-4
GO:0007017 microtubule-based process 3.387443e-4
GO:0050670 regulation of lymphocyte proliferation 3.407714e-4
GO:0006685 sphingomyelin catabolic process 3.420077e-4
GO:0051898 negative regulation of protein kinase B signaling cascade 3.425722e-4
GO:0071316 cellular response to nicotine 3.453557e-4
GO:0002439 chronic inflammatory response to antigenic stimulus 3.453557e-4
GO:2000351 regulation of endothelial cell apoptosis 3.458380e-4
GO:0002697 regulation of immune effector process 3.482741e-4
GO:0002683 negative regulation of immune system process 3.565854e-4
GO:0007275 multicellular organismal development 3.575756e-4
GO:0032418 lysosome localization 3.600871e-4
GO:0007493 endodermal cell fate determination 3.611268e-4
GO:0048878 chemical homeostasis 3.642746e-4
GO:0048821 erythrocyte development 3.686546e-4
GO:0043001 Golgi to plasma membrane protein transport 3.730775e-4
GO:0070663 regulation of leukocyte proliferation 3.736347e-4
GO:0031581 hemidesmosome assembly 3.766732e-4
GO:0071375 cellular response to peptide hormone stimulus 3.783723e-4
GO:0048286 lung alveolus development 4.047864e-4
GO:0031649 heat generation 4.065213e-4
GO:0009052 pentose-phosphate shunt, non-oxidative branch 4.068253e-4
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 4.089885e-4
GO:0042330 taxis 4.211132e-4
GO:0045075 regulation of interleukin-12 biosynthetic process 4.228337e-4
GO:0019852 L-ascorbic acid metabolic process 4.271203e-4
GO:0008219 cell death 4.288590e-4
GO:0002024 diet induced thermogenesis 4.344793e-4
GO:0032088 negative regulation of NF-kappaB transcription factor activity 4.385078e-4
GO:0034393 positive regulation of smooth muscle cell apoptosis 4.453925e-4
GO:0009966 regulation of signal transduction 4.550869e-4
GO:0048771 tissue remodeling 4.646569e-4
GO:0032816 positive regulation of natural killer cell activation 4.694467e-4
GO:0030889 negative regulation of B cell proliferation 4.745940e-4
GO:0016265 death 4.880232e-4
GO:0042102 positive regulation of T cell proliferation 4.895972e-4
GO:0014874 response to stimulus involved in regulation of muscle adaptation 4.907301e-4
GO:0009181 purine ribonucleoside diphosphate catabolic process 5.093294e-4
GO:0051541 elastin metabolic process 5.123235e-4
GO:2000352 negative regulation of endothelial cell apoptosis 5.154018e-4
GO:0002520 immune system development 5.307434e-4
GO:0045123 cellular extravasation 5.336682e-4
GO:0042129 regulation of T cell proliferation 5.347337e-4
GO:0006704 glucocorticoid biosynthetic process 5.380071e-4
GO:0002444 myeloid leukocyte mediated immunity 5.385265e-4
GO:0019218 regulation of steroid metabolic process 5.432904e-4
GO:0033043 regulation of organelle organization 5.496695e-4
GO:0006833 water transport 5.572840e-4
GO:0010677 negative regulation of cellular carbohydrate metabolic process 5.592019e-4
GO:0043279 response to alkaloid 5.643875e-4
GO:0007519 skeletal muscle tissue development 5.671832e-4
GO:0042780 tRNA 3'-end processing 5.751221e-4
GO:0051893 regulation of focal adhesion assembly 5.834749e-4
GO:0034115 negative regulation of heterotypic cell-cell adhesion 5.921981e-4
GO:0031122 cytoplasmic microtubule organization 5.939960e-4
GO:0001711 endodermal cell fate commitment 5.939960e-4
GO:0042345 regulation of NF-kappaB import into nucleus 5.950980e-4
GO:0006700 C21-steroid hormone biosynthetic process 6.024582e-4
GO:0051259 protein oligomerization 6.105865e-4
GO:0043271 negative regulation of ion transport 6.176426e-4
GO:0000729 DNA double-strand break processing 6.186295e-4
GO:0043255 regulation of carbohydrate biosynthetic process 6.226755e-4
GO:0032911 negative regulation of transforming growth factor beta1 production 6.435178e-4
GO:0046006 regulation of activated T cell proliferation 6.435591e-4
GO:0048278 vesicle docking 6.438437e-4
GO:0060627 regulation of vesicle-mediated transport 6.486654e-4
GO:0046483 heterocycle metabolic process 6.523417e-4
GO:0046649 lymphocyte activation 6.552229e-4
GO:0048534 hemopoietic or lymphoid organ development 6.676902e-4
GO:0051462 regulation of cortisol secretion 6.687382e-4
GO:0002839 positive regulation of immune response to tumor cell 6.699403e-4
GO:0032095 regulation of response to food 6.716917e-4
GO:0006681 galactosylceramide metabolic process 6.768267e-4
GO:0002639 positive regulation of immunoglobulin production 6.772572e-4
GO:0010466 negative regulation of peptidase activity 6.947104e-4
GO:0006915 apoptosis 6.966089e-4
GO:0021502 neural fold elevation formation 7.042276e-4
GO:0048731 system development 7.083643e-4
GO:0046058 cAMP metabolic process 7.097074e-4
GO:0042044 fluid transport 7.132771e-4
GO:0015706 nitrate transport 7.256766e-4
GO:0002355 detection of tumor cell 7.256766e-4
GO:0009450 gamma-aminobutyric acid catabolic process 7.256766e-4
GO:0000920 cytokinetic cell separation 7.262046e-4
GO:0016553 base conversion or substitution editing 7.274090e-4
GO:0010883 regulation of lipid storage 7.376857e-4
GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib 7.396020e-4
GO:0006171 cAMP biosynthetic process 7.563040e-4
GO:0030097 hemopoiesis 7.589007e-4
GO:0010470 regulation of gastrulation 7.615435e-4
GO:0071732 cellular response to nitric oxide 7.742436e-4
GO:0032909 regulation of transforming growth factor beta2 production 7.933534e-4
GO:0002093 auditory receptor cell morphogenesis 7.933534e-4
GO:0032012 regulation of ARF protein signal transduction 7.989823e-4
GO:0015031 protein transport 8.142045e-4
GO:0045576 mast cell activation 8.420062e-4
GO:0010954 positive regulation of protein processing 8.523201e-4
GO:0002053 positive regulation of mesenchymal cell proliferation 8.526232e-4
GO:0042851 L-alanine metabolic process 8.616143e-4
GO:0032715 negative regulation of interleukin-6 production 8.690243e-4
GO:0046426 negative regulation of JAK-STAT cascade 8.881499e-4
GO:0001975 response to amphetamine 8.897654e-4
GO:0032675 regulation of interleukin-6 production 9.003551e-4
GO:0032621 interleukin-18 production 9.057868e-4
GO:0002638 negative regulation of immunoglobulin production 9.057868e-4
GO:0001811 negative regulation of type I hypersensitivity 9.057868e-4
GO:0050801 ion homeostasis 9.123216e-4
GO:0006467 protein thiol-disulfide exchange 9.151644e-4
GO:0002837 regulation of immune response to tumor cell 9.171187e-4
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 9.207778e-4
GO:0050756 fractalkine metabolic process 9.278433e-4
GO:0033595 response to genistein 9.278433e-4
GO:0006059 hexitol metabolic process 9.278433e-4
GO:0006701 progesterone biosynthetic process 9.278433e-4
GO:0021793 chemorepulsion of branchiomotor axon 9.278433e-4
GO:0001666 response to hypoxia 9.288762e-4
GO:0010884 positive regulation of lipid storage 9.451363e-4
GO:0009068 aspartate family amino acid catabolic process 9.631260e-4
GO:0008584 male gonad development 9.650958e-4
GO:0032908 regulation of transforming growth factor beta1 production 9.670333e-4
GO:0006635 fatty acid beta-oxidation 9.707149e-4
GO:0021610 facial nerve morphogenesis 9.910165e-4
GO:0005979 regulation of glycogen biosynthetic process 9.922648e-4
GO:0008285 negative regulation of cell proliferation 1.001338e-3
GO:0032693 negative regulation of interleukin-10 production 1.007102e-3
GO:0030220 platelet formation 1.017327e-3
GO:0001659 temperature homeostasis 1.022743e-3
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 1.033268e-3
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 1.042601e-3
GO:0042220 response to cocaine 1.052575e-3
GO:0001816 cytokine production 1.055464e-3
GO:0045184 establishment of protein localization 1.058384e-3
GO:0048522 positive regulation of cellular process 1.064195e-3
GO:0050798 activated T cell proliferation 1.068767e-3
GO:0021954 central nervous system neuron development 1.073493e-3
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 1.105281e-3
GO:0030098 lymphocyte differentiation 1.113814e-3
GO:0022029 telencephalon cell migration 1.125045e-3
GO:0015672 monovalent inorganic cation transport 1.155442e-3
GO:0071634 regulation of transforming growth factor beta production 1.173445e-3
GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.173445e-3
GO:0019395 fatty acid oxidation 1.190371e-3
GO:0071805 potassium ion transmembrane transport 1.193404e-3
GO:0051900 regulation of mitochondrial depolarization 1.199306e-3
GO:0030850 prostate gland development 1.200758e-3
GO:0021884 forebrain neuron development 1.204657e-3
GO:0051295 establishment of meiotic spindle localization 1.207433e-3
GO:0050793 regulation of developmental process 1.236127e-3
GO:0009628 response to abiotic stimulus 1.240684e-3
GO:0042110 T cell activation 1.248228e-3
GO:0030500 regulation of bone mineralization 1.263502e-3