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Novel motif:50

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name:motif50_GTCCNA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0051001 negative regulation of nitric-oxide synthase activity 1.543495e-9
GO:0035269 protein O-linked mannosylation 3.681316e-9
GO:0015742 alpha-ketoglutarate transport 3.011886e-8
GO:0046655 folic acid metabolic process 8.358726e-8
GO:0072109 glomerular mesangium development 1.419236e-7
GO:0006457 protein folding 1.606816e-7
GO:2000249 regulation of actin cytoskeleton reorganization 1.881829e-7
GO:0045947 negative regulation of translational initiation 4.938949e-7
GO:0050909 sensory perception of taste 5.306801e-7
GO:0043249 erythrocyte maturation 5.575751e-7
GO:0030853 negative regulation of granulocyte differentiation 7.023668e-7
GO:0000956 nuclear-transcribed mRNA catabolic process 1.219870e-6
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1.486196e-6
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 1.865095e-6
GO:0006415 translational termination 1.925446e-6
GO:0043241 protein complex disassembly 2.683473e-6
GO:0072110 glomerular mesangial cell proliferation 3.335516e-6
GO:0007274 neuromuscular synaptic transmission 4.167013e-6
GO:0006414 translational elongation 5.092434e-6
GO:0019058 viral infectious cycle 5.569305e-6
GO:0042254 ribosome biogenesis 6.427232e-6
GO:0031365 N-terminal protein amino acid modification 6.807930e-6
GO:0032754 positive regulation of interleukin-5 production 7.444741e-6
GO:0019083 viral transcription 8.119354e-6
GO:0060712 spongiotrophoblast layer development 8.137884e-6
GO:0006402 mRNA catabolic process 8.752253e-6
GO:0006401 RNA catabolic process 9.142603e-6
GO:0043624 cellular protein complex disassembly 9.277312e-6
GO:0060457 negative regulation of digestive system process 1.059976e-5
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.129760e-5
GO:0016072 rRNA metabolic process 1.150181e-5
GO:0060713 labyrinthine layer morphogenesis 1.274240e-5
GO:0010424 DNA methylation on cytosine within a CG sequence 1.405561e-5
GO:0060711 labyrinthine layer development 1.510089e-5
GO:0006760 folic acid-containing compound metabolic process 1.804256e-5
GO:0002502 peptide antigen assembly with MHC class I protein complex 1.861318e-5
GO:0006304 DNA modification 2.750508e-5
GO:0006364 rRNA processing 2.794465e-5
GO:0071504 cellular response to heparin 2.797466e-5
GO:0046618 drug export 2.804246e-5
GO:0017148 negative regulation of translation 2.894724e-5
GO:0043045 DNA methylation involved in embryo development 3.039460e-5
GO:0051973 positive regulation of telomerase activity 3.091292e-5
GO:0030719 P granule organization 3.192900e-5
GO:0071593 lymphocyte aggregation 3.392742e-5
GO:0031848 protection from non-homologous end joining at telomere 3.528790e-5
GO:0040030 regulation of molecular function, epigenetic 3.932592e-5
GO:2000251 positive regulation of actin cytoskeleton reorganization 3.932592e-5
GO:0070489 T cell aggregation 3.972720e-5
GO:0030421 defecation 3.972720e-5
GO:0032202 telomere assembly 4.090073e-5
GO:0060708 spongiotrophoblast differentiation 4.116830e-5
GO:0002268 follicular dendritic cell differentiation 4.614832e-5
GO:0009142 nucleoside triphosphate biosynthetic process 4.696145e-5
GO:0033233 regulation of protein sumoylation 4.963080e-5
GO:0010897 negative regulation of triglyceride catabolic process 5.048116e-5
GO:0010987 negative regulation of high-density lipoprotein particle clearance 5.048116e-5
GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger 5.358055e-5
GO:0001977 renal system process involved in regulation of blood volume 5.497784e-5
GO:0032984 macromolecular complex disassembly 5.583916e-5
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 5.850360e-5
GO:0009258 10-formyltetrahydrofolate catabolic process 6.049519e-5
GO:0003105 negative regulation of glomerular filtration 6.330099e-5
GO:0051668 localization within membrane 6.712614e-5
GO:0050779 RNA destabilization 6.729343e-5
GO:0060669 embryonic placenta morphogenesis 7.096145e-5
GO:0051205 protein insertion into membrane 7.298885e-5
GO:0070172 positive regulation of tooth mineralization 7.307570e-5
GO:0046499 S-adenosylmethioninamine metabolic process 7.598915e-5
GO:0006505 GPI anchor metabolic process 7.653605e-5
GO:0009145 purine nucleoside triphosphate biosynthetic process 8.010997e-5
GO:0060306 regulation of membrane repolarization 8.053327e-5
GO:0042558 pteridine-containing compound metabolic process 8.348579e-5
GO:0090196 regulation of chemokine secretion 9.210421e-5
GO:0071503 response to heparin 9.210421e-5
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 9.492237e-5
GO:0018023 peptidyl-lysine trimethylation 9.828032e-5
GO:0061101 neuroendocrine cell differentiation 9.877936e-5
GO:0006506 GPI anchor biosynthetic process 1.005504e-4
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1.078533e-4
GO:0006700 C21-steroid hormone biosynthetic process 1.140907e-4
GO:0009201 ribonucleoside triphosphate biosynthetic process 1.145702e-4
GO:0030968 endoplasmic reticulum unfolded protein response 1.153262e-4
GO:0006400 tRNA modification 1.209326e-4
GO:0006695 cholesterol biosynthetic process 1.277871e-4
GO:0045842 positive regulation of mitotic metaphase/anaphase transition 1.402428e-4
GO:0016126 sterol biosynthetic process 1.432967e-4
GO:0060591 chondroblast differentiation 1.444704e-4
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 1.473462e-4
GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.508793e-4
GO:0034623 cellular macromolecular complex disassembly 1.548722e-4
GO:0043089 positive regulation of Cdc42 GTPase activity 1.603513e-4
GO:0060621 negative regulation of cholesterol import 1.653234e-4
GO:0032864 activation of Cdc42 GTPase activity 1.653234e-4
GO:0046939 nucleotide phosphorylation 1.673942e-4
GO:0060620 regulation of cholesterol import 1.787736e-4
GO:0090197 positive regulation of chemokine secretion 1.831410e-4
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1.831410e-4
GO:0072126 positive regulation of glomerular mesangial cell proliferation 1.906437e-4
GO:0071506 cellular response to mycophenolic acid 1.906437e-4
GO:0042908 xenobiotic transport 1.991714e-4
GO:0060670 branching involved in embryonic placenta morphogenesis 2.059551e-4
GO:0032736 positive regulation of interleukin-13 production 2.142473e-4
GO:0044027 hypermethylation of CpG island 2.184787e-4
GO:0022417 protein maturation by protein folding 2.222728e-4
GO:2000649 regulation of sodium ion transmembrane transporter activity 2.314458e-4
GO:0034470 ncRNA processing 2.315253e-4
GO:0019542 propionate biosynthetic process 2.354465e-4
GO:0019413 acetate biosynthetic process 2.354465e-4
GO:0018192 enzyme active site formation via L-cysteine persulfide 2.354465e-4
GO:0015761 mannose transport 2.354465e-4
GO:0070988 demethylation 2.490628e-4
GO:0034340 response to type I interferon 2.595927e-4
GO:0006335 DNA replication-dependent nucleosome assembly 2.690316e-4
GO:0032782 bile acid secretion 2.691948e-4
GO:0051208 sequestering of calcium ion 2.726669e-4
GO:0014819 regulation of skeletal muscle contraction 2.726669e-4
GO:0046533 negative regulation of photoreceptor cell differentiation 2.754812e-4
GO:0045604 regulation of epidermal cell differentiation 2.984560e-4
GO:0046498 S-adenosylhomocysteine metabolic process 3.001433e-4
GO:0030852 regulation of granulocyte differentiation 3.057423e-4
GO:0007538 primary sex determination 3.077987e-4
GO:0032203 telomere formation via telomerase 3.094015e-4
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 3.240264e-4
GO:0006826 iron ion transport 3.372793e-4
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 3.425862e-4
GO:0060084 synaptic transmission involved in micturition 3.483738e-4
GO:0061037 negative regulation of cartilage development 3.502470e-4
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 3.630285e-4
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 3.630285e-4
GO:0032938 negative regulation of translation in response to oxidative stress 3.662719e-4
GO:0031591 wybutosine biosynthetic process 3.662719e-4
GO:0010616 negative regulation of cardiac muscle adaptation 3.728131e-4
GO:0009098 leucine biosynthetic process 3.728131e-4
GO:0006550 isoleucine catabolic process 3.728131e-4
GO:0006754 ATP biosynthetic process 3.839105e-4
GO:0034442 regulation of lipoprotein oxidation 3.839985e-4
GO:0034227 tRNA thio-modification 3.839985e-4
GO:0002098 tRNA wobble uridine modification 3.839985e-4
GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response 3.975036e-4
GO:0042481 regulation of odontogenesis 4.062652e-4
GO:0046292 formaldehyde metabolic process 4.064766e-4
GO:0030573 bile acid catabolic process 4.064766e-4
GO:0035039 male pronucleus assembly 4.095546e-4
GO:0045814 negative regulation of gene expression, epigenetic 4.099138e-4
GO:0002636 positive regulation of germinal center formation 4.132375e-4
GO:0006694 steroid biosynthetic process 4.145332e-4
GO:0035854 eosinophil fate commitment 4.530202e-4
GO:0030222 eosinophil differentiation 4.530202e-4
GO:0071353 cellular response to interleukin-4 4.570064e-4
GO:0035552 oxidative single-stranded DNA demethylation 4.619234e-4
GO:0060337 type I interferon-mediated signaling pathway 4.643556e-4
GO:0060455 negative regulation of gastric acid secretion 4.891728e-4
GO:0060381 positive regulation of single-stranded telomeric DNA binding 4.891728e-4
GO:0007063 regulation of sister chromatid cohesion 4.908756e-4
GO:0046474 glycerophospholipid biosynthetic process 5.027539e-4
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 5.028092e-4
GO:0032055 negative regulation of translation in response to stress 5.345354e-4
GO:0010452 histone H3-K36 methylation 5.402399e-4
GO:0030300 regulation of intestinal cholesterol absorption 5.637678e-4
GO:0051972 regulation of telomerase activity 5.657310e-4
GO:0060706 cell differentiation involved in embryonic placenta development 5.746913e-4
GO:0070670 response to interleukin-4 5.820041e-4
GO:0032312 regulation of ARF GTPase activity 5.946027e-4
GO:0015746 citrate transport 6.184724e-4
GO:0061103 carotid body glomus cell differentiation 6.294792e-4
GO:0061104 adrenal chromaffin cell differentiation 6.294792e-4
GO:0061102 stomach neuroendocrine cell differentiation 6.294792e-4
GO:0071259 cellular response to magnetism 6.294792e-4
GO:0061100 lung neuroendocrine cell differentiation 6.294792e-4
GO:0007400 neuroblast fate determination 6.294792e-4
GO:0003359 noradrenergic neuron fate commitment 6.294792e-4
GO:0060163 subpallium neuron fate commitment 6.294792e-4
GO:0060165 regulation of timing of subpallium neuron differentiation 6.294792e-4
GO:0007028 cytoplasm organization 6.307543e-4
GO:0035814 negative regulation of renal sodium excretion 7.071318e-4
GO:0060299 negative regulation of sarcomere organization 7.547701e-4
GO:0033292 T-tubule organization 7.547701e-4
GO:0048790 maintenance of presynaptic active zone structure 7.622114e-4
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 7.622114e-4
GO:0022613 ribonucleoprotein complex biogenesis 7.639613e-4
GO:0070170 regulation of tooth mineralization 8.348510e-4
GO:0010988 regulation of low-density lipoprotein particle clearance 8.450114e-4
GO:0015884 folic acid transport 8.465422e-4
GO:0072298 regulation of metanephric glomerulus development 8.765947e-4
GO:0032057 negative regulation of translational initiation in response to stress 8.829319e-4
GO:0045835 negative regulation of meiosis 9.176457e-4
GO:0070849 response to epidermal growth factor stimulus 9.205172e-4
GO:0045358 negative regulation of interferon-beta biosynthetic process 9.475335e-4
GO:0090084 negative regulation of inclusion body assembly 9.507454e-4
GO:0032415 regulation of sodium:hydrogen antiporter activity 9.566142e-4
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 9.800442e-4
GO:0042797 tRNA transcription from RNA polymerase III promoter 9.800442e-4
GO:0070483 detection of hypoxia 9.887079e-4
GO:0010989 negative regulation of low-density lipoprotein particle clearance 9.892181e-4
GO:0071843 cellular component biogenesis at cellular level 1.021315e-3
GO:0000084 S phase of mitotic cell cycle 1.055772e-3
GO:0043461 proton-transporting ATP synthase complex assembly 1.080083e-3
GO:0022415 viral reproductive process 1.082600e-3
GO:0006501 C-terminal protein lipidation 1.107726e-3
GO:0006704 glucocorticoid biosynthetic process 1.140861e-3
GO:0048873 homeostasis of number of cells within a tissue 1.167231e-3
GO:0006458 'de novo' protein folding 1.200153e-3
GO:0046778 modification by virus of host mRNA processing 1.213570e-3
GO:0030046 parallel actin filament bundle assembly 1.213570e-3
GO:0032200 telomere organization 1.232905e-3
GO:0003417 growth plate cartilage development 1.238371e-3
GO:0033153 T cell receptor V(D)J recombination 1.264009e-3
GO:0002033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure 1.291452e-3
GO:0031118 rRNA pseudouridine synthesis 1.297104e-3
GO:0023035 CD40 signaling pathway 1.297104e-3
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 1.435424e-3
GO:0061032 visceral serous pericardium development 1.435424e-3
GO:0006342 chromatin silencing 1.459575e-3
GO:0032674 regulation of interleukin-5 production 1.485478e-3
GO:0018410 C-terminal protein amino acid modification 1.502730e-3
GO:0051320 S phase 1.526489e-3
GO:0007296 vitellogenesis 1.540593e-3
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 1.564062e-3
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity 1.564062e-3
GO:0043418 homocysteine catabolic process 1.564062e-3
GO:0006535 cysteine biosynthetic process from serine 1.564062e-3
GO:0019343 cysteine biosynthetic process via cystathionine 1.564062e-3
GO:0019346 transsulfuration 1.564062e-3
GO:0048243 norepinephrine secretion 1.593860e-3
GO:0006835 dicarboxylic acid transport 1.604644e-3
GO:0003093 regulation of glomerular filtration 1.626502e-3
GO:0051323 metaphase 1.631893e-3
GO:0006942 regulation of striated muscle contraction 1.651913e-3
GO:0035645 enteric smooth muscle cell differentiation 1.718117e-3
GO:0008272 sulfate transport 1.724753e-3
GO:0006482 protein demethylation 1.727647e-3
GO:0051238 sequestering of metal ion 1.790033e-3
GO:0014741 negative regulation of muscle hypertrophy 1.813171e-3
GO:0060707 trophoblast giant cell differentiation 1.896906e-3
GO:0001892 embryonic placenta development 1.910411e-3
GO:0006621 protein retention in ER lumen 1.920157e-3
GO:0000724 double-strand break repair via homologous recombination 1.935694e-3
GO:0051084 'de novo' posttranslational protein folding 1.964065e-3
GO:0032416 negative regulation of sodium:hydrogen antiporter activity 1.973513e-3
GO:0018293 protein-FAD linkage 1.973513e-3
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 1.973513e-3
GO:0060351 cartilage development involved in endochondral bone morphogenesis 1.973581e-3
GO:0009304 tRNA transcription 2.015854e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 2.028250e-3
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.030756e-3
GO:0010701 positive regulation of norepinephrine secretion 2.035754e-3
GO:0010172 embryonic body morphogenesis 2.119732e-3
GO:0034635 glutathione transport 2.171107e-3
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 2.171107e-3
GO:0019478 D-amino acid catabolic process 2.171107e-3
GO:0000725 recombinational repair 2.189626e-3
GO:0031296 B cell costimulation 2.303365e-3
GO:0022411 cellular component disassembly 2.322813e-3
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 2.334988e-3
GO:0097039 protein linear polyubiquitination 2.338619e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 2.377873e-3
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.391237e-3
GO:0000730 DNA recombinase assembly 2.547861e-3
GO:0032796 uropod organization 2.565344e-3
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development 2.578813e-3
GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity 2.578813e-3
GO:0071670 smooth muscle cell chemotaxis 2.668162e-3
GO:0060981 cell migration involved in coronary angiogenesis 2.668162e-3
GO:0090346 cellular organofluorine metabolic process 2.668162e-3
GO:0046210 nitric oxide catabolic process 2.668162e-3
GO:0060764 cell-cell signaling involved in mammary gland development 2.668162e-3
GO:0043602 nitrate catabolic process 2.668162e-3
GO:0046294 formaldehyde catabolic process 2.668162e-3
GO:0048692 negative regulation of axon extension involved in regeneration 2.717088e-3
GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly 2.800553e-3
GO:0032780 negative regulation of ATPase activity 2.809466e-3
GO:0071347 cellular response to interleukin-1 2.820139e-3
GO:0030490 maturation of SSU-rRNA 2.851661e-3
GO:2000195 negative regulation of female gonad development 2.935970e-3
GO:0006348 chromatin silencing at telomere 2.954248e-3
GO:0072329 monocarboxylic acid catabolic process 2.962006e-3
GO:0045630 positive regulation of T-helper 2 cell differentiation 2.972008e-3
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 2.995896e-3
GO:0016926 protein desumoylation 2.995896e-3
GO:0042267 natural killer cell mediated cytotoxicity 3.016357e-3
GO:0016577 histone demethylation 3.092331e-3
GO:0006598 polyamine catabolic process 3.098429e-3
GO:0002158 osteoclast proliferation 3.098429e-3
GO:0002762 negative regulation of myeloid leukocyte differentiation 3.130739e-3
GO:0009152 purine ribonucleotide biosynthetic process 3.133189e-3
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 3.151434e-3
GO:0021548 pons development 3.186994e-3
GO:0031444 slow-twitch skeletal muscle fiber contraction 3.191864e-3
GO:0007497 posterior midgut development 3.256181e-3
GO:0060087 relaxation of vascular smooth muscle 3.258886e-3
GO:0071044 histone mRNA catabolic process 3.341759e-3
GO:0021588 cerebellum formation 3.377332e-3
GO:0022004 midbrain-hindbrain boundary maturation during brain development 3.377332e-3
GO:2000002 negative regulation of DNA damage checkpoint 3.377332e-3
GO:0021551 central nervous system morphogenesis 3.377332e-3
GO:0002082 regulation of oxidative phosphorylation 3.377332e-3
GO:0003106 negative regulation of glomerular filtration by angiotensin 3.377332e-3
GO:0006843 mitochondrial citrate transport 3.377332e-3
GO:0014895 smooth muscle hypertrophy 3.377332e-3
GO:0042274 ribosomal small subunit biogenesis 3.520625e-3
GO:0016264 gap junction assembly 3.543587e-3
GO:0030212 hyaluronan metabolic process 3.586385e-3
GO:0006266 DNA ligation 3.593689e-3
GO:2000194 regulation of female gonad development 3.631775e-3
GO:0006307 DNA dealkylation involved in DNA repair 3.719888e-3
GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis 3.729719e-3
GO:0006306 DNA methylation 3.764740e-3
GO:0008052 sensory organ boundary specification 3.813203e-3
GO:0003416 endochondral bone growth 3.910423e-3
GO:0032020 ISG15-protein conjugation 3.965098e-3
GO:0033235 positive regulation of protein sumoylation 3.973453e-3
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 3.978308e-3
GO:0060049 regulation of protein glycosylation 4.081590e-3
GO:0071315 cellular response to morphine 4.089599e-3
GO:0071307 cellular response to vitamin K 4.089599e-3
GO:0090324 negative regulation of oxidative phosphorylation 4.089599e-3
GO:0071448 cellular response to alkyl hydroperoxide 4.089599e-3
GO:0071403 cellular response to high density lipoprotein particle stimulus 4.089599e-3
GO:0050904 diapedesis 4.089599e-3
GO:0031269 pseudopodium assembly 4.089599e-3
GO:0010255 glucose mediated signaling pathway 4.089599e-3
GO:0032900 negative regulation of neurotrophin production 4.089599e-3
GO:0032244 positive regulation of nucleoside transport 4.089599e-3
GO:0016233 telomere capping 4.157213e-3
GO:0071845 cellular component disassembly at cellular level 4.215186e-3
GO:0019062 virion attachment to host cell surface receptor 4.247068e-3
GO:0070344 regulation of fat cell proliferation 4.338849e-3
GO:0035511 oxidative DNA demethylation 4.339505e-3
GO:0045747 positive regulation of Notch signaling pathway 4.341364e-3
GO:0045616 regulation of keratinocyte differentiation 4.479012e-3
GO:0019884 antigen processing and presentation of exogenous antigen 4.485979e-3
GO:0045872 positive regulation of rhodopsin gene expression 4.507969e-3
GO:0006467 protein thiol-disulfide exchange 4.522184e-3
GO:0007386 compartment pattern specification 4.656177e-3
GO:0051775 response to redox state 4.686380e-3
GO:0043462 regulation of ATPase activity 4.703821e-3
GO:0035573 N-terminal peptidyl-serine trimethylation 4.705927e-3
GO:0035572 N-terminal peptidyl-serine dimethylation 4.705927e-3
GO:0018016 N-terminal peptidyl-proline dimethylation 4.705927e-3
GO:0018012 N-terminal peptidyl-alanine trimethylation 4.705927e-3
GO:0000089 mitotic metaphase 4.756891e-3
GO:0009119 ribonucleoside metabolic process 4.807835e-3
GO:0016139 glycoside catabolic process 4.917253e-3
GO:0021506 anterior neuropore closure 4.917253e-3
GO:0034384 high-density lipoprotein particle clearance 5.037299e-3
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 5.065513e-3
GO:0045006 DNA deamination 5.067875e-3
GO:0045820 negative regulation of glycolysis 5.116025e-3
GO:0006684 sphingomyelin metabolic process 5.119960e-3
GO:0006661 phosphatidylinositol biosynthetic process 5.184000e-3
GO:0031952 regulation of protein autophosphorylation 5.206330e-3
GO:0006635 fatty acid beta-oxidation 5.209225e-3
GO:0018198 peptidyl-cysteine modification 5.262404e-3
GO:0060051 negative regulation of protein glycosylation 5.326132e-3
GO:0060716 labyrinthine layer blood vessel development 5.348521e-3
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity 5.428176e-3
GO:0032074 negative regulation of nuclease activity 5.428176e-3
GO:0031627 telomeric loop formation 5.428176e-3
GO:0015074 DNA integration 5.483872e-3
GO:0007620 copulation 5.552017e-3
GO:2000117 negative regulation of cysteine-type endopeptidase activity 5.612787e-3
GO:0048298 positive regulation of isotype switching to IgA isotypes 5.615475e-3
GO:0070328 triglyceride homeostasis 5.618922e-3
GO:0050435 beta-amyloid metabolic process 5.646733e-3
GO:0010536 positive regulation of activation of Janus kinase activity 5.679447e-3
GO:0046314 phosphocreatine biosynthetic process 5.697239e-3
GO:0048733 sebaceous gland development 5.804400e-3
GO:0014807 regulation of somitogenesis 5.804400e-3
GO:0001881 receptor recycling 5.804400e-3
GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness 5.804400e-3
GO:0046813 virion attachment, binding of host cell surface receptor 5.812649e-3
GO:0002250 adaptive immune response 5.873992e-3
GO:0018206 peptidyl-methionine modification 5.916115e-3
GO:0006651 diacylglycerol biosynthetic process 5.952925e-3
GO:0008215 spermine metabolic process 5.961623e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 6.035673e-3
GO:0048632 negative regulation of skeletal muscle tissue growth 6.114394e-3
GO:0002017 regulation of blood volume by renal aldosterone 6.114394e-3
GO:0090230 regulation of centromere complex assembly 6.157825e-3
GO:0034205 beta-amyloid formation 6.157825e-3
GO:0035308 negative regulation of protein dephosphorylation 6.290322e-3
GO:0071356 cellular response to tumor necrosis factor 6.315598e-3
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.346029e-3
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 6.375780e-3
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 6.381571e-3
GO:0001974 blood vessel remodeling 6.488999e-3
GO:0045343 regulation of MHC class I biosynthetic process 6.526130e-3
GO:0032656 regulation of interleukin-13 production 6.605997e-3
GO:0018393 internal peptidyl-lysine acetylation 6.656681e-3
GO:0051958 methotrexate transport 6.920356e-3
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 6.920356e-3
GO:0019388 galactose catabolic process 6.920356e-3
GO:0010631 epithelial cell migration 6.945966e-3
GO:0042711 maternal behavior 6.998794e-3
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 7.036140e-3
GO:0032753 positive regulation of interleukin-4 production 7.038035e-3
GO:0007184 SMAD protein import into nucleus 7.038035e-3
GO:0032776 DNA methylation on cytosine 7.153712e-3
GO:0010626 negative regulation of Schwann cell proliferation 7.153712e-3
GO:2000016 negative regulation of determination of dorsal identity 7.158898e-3
GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.158898e-3
GO:0045796 negative regulation of intestinal cholesterol absorption 7.158898e-3
GO:0032972 regulation of muscle filament sliding speed 7.158898e-3
GO:0010949 negative regulation of intestinal phytosterol absorption 7.158898e-3
GO:0060784 regulation of cell proliferation involved in tissue homeostasis 7.162496e-3
GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis 7.162496e-3
GO:0060517 epithelial cell proliferation involved in prostatic bud elongation 7.162496e-3
GO:0035622 intrahepatic bile duct development 7.162496e-3
GO:0003415 chondrocyte hypertrophy 7.162496e-3
GO:0019100 male germ-line sex determination 7.162496e-3
GO:0002467 germinal center formation 7.271893e-3
GO:0035364 thymine transport 7.296285e-3
GO:0035344 hypoxanthine transport 7.296285e-3
GO:0031658 negative regulation of cyclin-dependent protein kinase activity involved in G1/S 7.296285e-3
GO:0007092 activation of mitotic anaphase-promoting complex activity 7.296285e-3
GO:0015854 guanine transport 7.296285e-3
GO:0033687 osteoblast proliferation 7.339658e-3
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 7.339658e-3
GO:0000072 M phase specific microtubule process 7.358768e-3
GO:0072011 glomerular endothelium development 7.366295e-3
GO:0072144 glomerular mesangial cell development 7.366295e-3
GO:0007192 activation of adenylate cyclase activity by serotonin receptor signaling pathway 7.366295e-3
GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions 7.366295e-3
GO:0010529 negative regulation of transposition 7.391657e-3
GO:0031998 regulation of fatty acid beta-oxidation 7.478561e-3
GO:0001909 leukocyte mediated cytotoxicity 7.553748e-3
GO:0006346 methylation-dependent chromatin silencing 7.582820e-3
GO:0000413 protein peptidyl-prolyl isomerization 7.585817e-3
GO:0030382 sperm mitochondrion organization 7.602176e-3
GO:0032269 negative regulation of cellular protein metabolic process 7.746889e-3
GO:0002063 chondrocyte development 7.813118e-3
GO:0090192 regulation of glomerulus development 7.844081e-3
GO:0048821 erythrocyte development 7.903137e-3
GO:0018394 peptidyl-lysine acetylation 7.918965e-3
GO:0043046 DNA methylation involved in gamete generation 7.934977e-3
GO:0051365 cellular response to potassium ion starvation 7.937910e-3
GO:0009642 response to light intensity 7.937910e-3
GO:0006097 glyoxylate cycle 7.937910e-3
GO:0045759 negative regulation of action potential 8.070217e-3
GO:0090141 positive regulation of mitochondrial fission 8.093417e-3
GO:0070345 negative regulation of fat cell proliferation 8.093417e-3
GO:0030206 chondroitin sulfate biosynthetic process 8.188882e-3
GO:0006032 chitin catabolic process 8.470275e-3
GO:0051292 nuclear pore complex assembly 8.511327e-3
GO:0010712 regulation of collagen metabolic process 8.578640e-3
GO:0072529 pyrimidine-containing compound catabolic process 8.578640e-3
GO:0030238 male sex determination 8.602432e-3
GO:0006885 regulation of pH 8.724321e-3
GO:0070474 positive regulation of uterine smooth muscle contraction 8.764675e-3
GO:0009260 ribonucleotide biosynthetic process 8.916181e-3
GO:0015893 drug transport 9.023660e-3
GO:0022009 central nervous system vasculogenesis 9.234659e-3
GO:0006475 internal protein amino acid acetylation 9.326525e-3
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 9.364008e-3
GO:0009698 phenylpropanoid metabolic process 9.418863e-3
GO:0019448 L-cysteine catabolic process 9.511699e-3
GO:0070071 proton-transporting two-sector ATPase complex assembly 9.518914e-3
GO:0032965 regulation of collagen biosynthetic process 9.525750e-3
GO:0043304 regulation of mast cell degranulation 9.606550e-3
GO:0016071 mRNA metabolic process 9.642199e-3
GO:0030277 maintenance of gastrointestinal epithelium 9.666052e-3
GO:0019061 uncoating of virus 9.685892e-3
GO:0045626 negative regulation of T-helper 1 cell differentiation 9.814759e-3
GO:0006308 DNA catabolic process 9.914489e-3
GO:0035545 determination of left/right asymmetry in nervous system 9.922299e-3
GO:0007021 tubulin complex assembly 9.981973e-3
GO:0001782 B cell homeostasis 1.001376e-2
GO:0010522 regulation of calcium ion transport into cytosol 1.003900e-2
GO:0015891 siderophore transport 1.013409e-2
GO:0061014 positive regulation of mRNA catabolic process 1.013768e-2
GO:0006544 glycine metabolic process 1.028953e-2
GO:0070734 histone H3-K27 methylation 1.042423e-2
GO:0006720 isoprenoid metabolic process 1.043042e-2
GO:0043543 protein acylation 1.044154e-2
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.060550e-2
GO:0030220 platelet formation 1.060999e-2
GO:0044338 canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation 1.066391e-2
GO:0044339 canonical Wnt receptor signaling pathway involved in osteoblast differentiation 1.066391e-2
GO:0072166 posterior mesonephric tubule development 1.067368e-2
GO:0033057 multicellular organismal reproductive behavior 1.071187e-2
GO:0007597 blood coagulation, intrinsic pathway 1.078643e-2
GO:0010624 regulation of Schwann cell proliferation 1.080873e-2
GO:0015874 norepinephrine transport 1.086805e-2
GO:0010982 regulation of high-density lipoprotein particle clearance 1.098937e-2
GO:0051593 response to folic acid 1.126703e-2
GO:0048205 COPI coating of Golgi vesicle 1.128428e-2
GO:0090344 negative regulation of cell aging 1.140022e-2
GO:0006228 UTP biosynthetic process 1.140127e-2
GO:0006165 nucleoside diphosphate phosphorylation 1.140127e-2
GO:0006183 GTP biosynthetic process 1.140127e-2
GO:0061383 trabecula morphogenesis 1.147239e-2
GO:0050667 homocysteine metabolic process 1.149787e-2
GO:0006596 polyamine biosynthetic process 1.152812e-2
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity 1.153932e-2
GO:0016032 viral reproduction 1.168810e-2
GO:0008535 respiratory chain complex IV assembly 1.168923e-2
GO:0009116 nucleoside metabolic process 1.186694e-2
GO:0018924 mandelate metabolic process 1.188913e-2
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 1.189917e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0048298 positive regulation of isotype switching to IgA isotypes 5.087187e-16
GO:0090031 positive regulation of steroid hormone biosynthetic process 2.832160e-12
GO:0035094 response to nicotine 7.982866e-12
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.020642e-11
GO:0010893 positive regulation of steroid biosynthetic process 1.601122e-11
GO:0046886 positive regulation of hormone biosynthetic process 1.966811e-10
GO:0046628 positive regulation of insulin receptor signaling pathway 4.093426e-10
GO:0090030 regulation of steroid hormone biosynthetic process 2.772941e-9
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 2.944956e-9
GO:0002636 positive regulation of germinal center formation 5.262165e-9
GO:2000467 positive regulation of glycogen (starch) synthase activity 9.578403e-9
GO:0045980 negative regulation of nucleotide metabolic process 9.833822e-9
GO:0046889 positive regulation of lipid biosynthetic process 1.770414e-8
GO:0035691 macrophage migration inhibitory factor signaling pathway 1.863664e-8
GO:0030818 negative regulation of cAMP biosynthetic process 3.882423e-8
GO:0051897 positive regulation of protein kinase B signaling cascade 5.526059e-8
GO:0032352 positive regulation of hormone metabolic process 5.832364e-8
GO:2000465 regulation of glycogen (starch) synthase activity 7.200082e-8
GO:0048240 sperm capacitation 8.409858e-8
GO:0051085 chaperone mediated protein folding requiring cofactor 1.231205e-7
GO:0019730 antimicrobial humoral response 1.619595e-7
GO:0006693 prostaglandin metabolic process 2.154956e-7
GO:0070228 regulation of lymphocyte apoptosis 2.934126e-7
GO:0046885 regulation of hormone biosynthetic process 5.093592e-7
GO:0001516 prostaglandin biosynthetic process 5.315458e-7
GO:0010935 regulation of macrophage cytokine production 6.769577e-7
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 7.438149e-7
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 8.780937e-7
GO:0034505 tooth mineralization 1.246377e-6
GO:0019731 antibacterial humoral response 1.252636e-6
GO:0032963 collagen metabolic process 1.355870e-6
GO:0007586 digestion 1.491802e-6
GO:0051084 'de novo' posttranslational protein folding 1.522544e-6
GO:0044259 multicellular organismal macromolecule metabolic process 1.816453e-6
GO:0019724 B cell mediated immunity 1.855055e-6
GO:0060346 bone trabecula formation 2.068554e-6
GO:0002830 positive regulation of type 2 immune response 2.118199e-6
GO:0007288 sperm axoneme assembly 2.260931e-6
GO:0016064 immunoglobulin mediated immune response 2.977164e-6
GO:0044236 multicellular organismal metabolic process 3.713152e-6
GO:0090083 regulation of inclusion body assembly 3.856586e-6
GO:0070230 positive regulation of lymphocyte apoptosis 4.287194e-6
GO:0060674 placenta blood vessel development 4.484765e-6
GO:0051896 regulation of protein kinase B signaling cascade 5.882862e-6
GO:0002604 regulation of dendritic cell antigen processing and presentation 6.362905e-6
GO:0030307 positive regulation of cell growth 7.036806e-6
GO:0042104 positive regulation of activated T cell proliferation 7.538574e-6
GO:0045725 positive regulation of glycogen biosynthetic process 7.828713e-6
GO:0070232 regulation of T cell apoptosis 9.465540e-6
GO:2000273 positive regulation of receptor activity 9.836997e-6
GO:0031999 negative regulation of fatty acid beta-oxidation 1.079946e-5
GO:0045940 positive regulation of steroid metabolic process 1.616714e-5
GO:0045796 negative regulation of intestinal cholesterol absorption 1.657591e-5
GO:0010949 negative regulation of intestinal phytosterol absorption 1.657591e-5
GO:0009817 defense response to fungus, incompatible interaction 1.657591e-5
GO:0070234 positive regulation of T cell apoptosis 1.763477e-5
GO:0001957 intramembranous ossification 1.860685e-5
GO:0070243 regulation of thymocyte apoptosis 2.185849e-5
GO:0015816 glycine transport 2.275274e-5
GO:0060711 labyrinthine layer development 2.472393e-5
GO:0035082 axoneme assembly 2.616283e-5
GO:0032094 response to food 3.072929e-5
GO:0031017 exocrine pancreas development 3.102518e-5
GO:0045908 negative regulation of vasodilation 3.376311e-5
GO:0006668 sphinganine-1-phosphate metabolic process 3.466634e-5
GO:0071874 cellular response to norepinephrine stimulus 3.484939e-5
GO:0007286 spermatid development 3.912867e-5
GO:0030574 collagen catabolic process 4.344949e-5
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 4.402829e-5
GO:0046006 regulation of activated T cell proliferation 4.460900e-5
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 5.548651e-5
GO:0060631 regulation of meiosis I 5.651208e-5
GO:0010520 regulation of reciprocal meiotic recombination 5.847401e-5
GO:0014910 regulation of smooth muscle cell migration 6.618133e-5
GO:0070245 positive regulation of thymocyte apoptosis 6.923150e-5
GO:0060716 labyrinthine layer blood vessel development 7.194576e-5
GO:0002579 positive regulation of antigen processing and presentation 7.270266e-5
GO:0016140 O-glycoside metabolic process 7.346788e-5
GO:0060907 positive regulation of macrophage cytokine production 7.451195e-5
GO:0031536 positive regulation of exit from mitosis 7.484248e-5
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 8.107485e-5
GO:0090023 positive regulation of neutrophil chemotaxis 8.518011e-5
GO:0001553 luteinization 8.518011e-5
GO:0045581 negative regulation of T cell differentiation 8.704385e-5
GO:0006360 transcription from RNA polymerase I promoter 8.730454e-5
GO:0001961 positive regulation of cytokine-mediated signaling pathway 9.286319e-5
GO:0002906 negative regulation of mature B cell apoptosis 9.587299e-5
GO:0044243 multicellular organismal catabolic process 9.867483e-5
GO:2000107 negative regulation of leukocyte apoptosis 1.044622e-4
GO:0002577 regulation of antigen processing and presentation 1.099044e-4
GO:0090086 negative regulation of protein deubiquitination 1.121701e-4
GO:0010718 positive regulation of epithelial to mesenchymal transition 1.196099e-4
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.309989e-4
GO:0071422 succinate transmembrane transport 1.318219e-4
GO:0071300 cellular response to retinoic acid 1.329918e-4
GO:0070229 negative regulation of lymphocyte apoptosis 1.342275e-4
GO:0046069 cGMP catabolic process 1.411290e-4
GO:0046314 phosphocreatine biosynthetic process 1.494705e-4
GO:0043064 flagellum organization 1.531971e-4
GO:0051973 positive regulation of telomerase activity 1.542754e-4
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 1.542754e-4
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 1.542754e-4
GO:0060709 glycogen cell development involved in embryonic placenta development 1.604968e-4
GO:0002426 immunoglobulin production in mucosal tissue 1.605537e-4
GO:0090022 regulation of neutrophil chemotaxis 1.633486e-4
GO:2000106 regulation of leukocyte apoptosis 1.659346e-4
GO:0045834 positive regulation of lipid metabolic process 1.683468e-4
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.730751e-4
GO:0046322 negative regulation of fatty acid oxidation 1.923584e-4
GO:0051904 pigment granule transport 2.039145e-4
GO:0060323 head morphogenesis 2.085607e-4
GO:0051781 positive regulation of cell division 2.182295e-4
GO:0019285 glycine betaine biosynthetic process from choline 2.298381e-4
GO:0006383 transcription from RNA polymerase III promoter 2.298381e-4
GO:0046037 GMP metabolic process 2.345513e-4
GO:0071299 cellular response to vitamin A 2.372774e-4
GO:0050810 regulation of steroid biosynthetic process 2.501938e-4
GO:0009296 flagellum assembly 2.577540e-4
GO:0006513 protein monoubiquitination 2.644372e-4
GO:0060325 face morphogenesis 2.827508e-4
GO:0032402 melanosome transport 2.857296e-4
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 2.862118e-4
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2.930537e-4
GO:0010025 wax biosynthetic process 2.940719e-4
GO:0006669 sphinganine-1-phosphate biosynthetic process 3.027047e-4
GO:0002513 tolerance induction to self antigen 3.039571e-4
GO:0033523 histone H2B ubiquitination 3.222858e-4
GO:0001867 complement activation, lectin pathway 3.379617e-4
GO:0048515 spermatid differentiation 3.400656e-4
GO:0051444 negative regulation of ubiquitin-protein ligase activity 3.571447e-4
GO:2001021 negative regulation of response to DNA damage stimulus 3.593184e-4
GO:0002483 antigen processing and presentation of endogenous peptide antigen 3.793385e-4
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 3.812224e-4
GO:0031848 protection from non-homologous end joining at telomere 3.812224e-4
GO:0006438 valyl-tRNA aminoacylation 3.812224e-4
GO:0031573 intra-S DNA damage checkpoint 3.815510e-4
GO:0048016 inositol phosphate-mediated signaling 3.822486e-4
GO:0043154 negative regulation of caspase activity 3.843359e-4
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 4.058764e-4
GO:0001578 microtubule bundle formation 4.085072e-4
GO:0002455 humoral immune response mediated by circulating immunoglobulin 4.158344e-4
GO:0046755 non-lytic virus budding 4.317027e-4
GO:0006354 transcription elongation, DNA-dependent 4.347226e-4
GO:0060760 positive regulation of response to cytokine stimulus 4.445904e-4
GO:2000147 positive regulation of cell motility 4.499605e-4
GO:0048936 peripheral nervous system neuron axonogenesis 4.557367e-4
GO:0006780 uroporphyrinogen III biosynthetic process 4.557367e-4
GO:0017196 N-terminal peptidyl-methionine acetylation 4.557367e-4
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 4.592395e-4
GO:0072376 protein activation cascade 4.741719e-4
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 4.782728e-4
GO:0018158 protein oxidation 4.856016e-4
GO:0006208 pyrimidine base catabolic process 5.008337e-4
GO:0030050 vesicle transport along actin filament 5.420241e-4
GO:0045780 positive regulation of bone resorption 5.462560e-4
GO:0008286 insulin receptor signaling pathway 5.473921e-4
GO:0030335 positive regulation of cell migration 5.809391e-4
GO:0040017 positive regulation of locomotion 5.928995e-4
GO:0006412 translation 6.119665e-4
GO:0048631 regulation of skeletal muscle tissue growth 6.293354e-4
GO:0060457 negative regulation of digestive system process 6.293354e-4
GO:0042886 amide transport 6.346707e-4
GO:0032350 regulation of hormone metabolic process 6.348546e-4
GO:0010907 positive regulation of glucose metabolic process 6.455581e-4
GO:0045907 positive regulation of vasoconstriction 6.609338e-4
GO:0010225 response to UV-C 6.677649e-4
GO:0060947 cardiac vascular smooth muscle cell differentiation 6.689362e-4
GO:0090084 negative regulation of inclusion body assembly 6.830273e-4
GO:0016485 protein processing 6.856675e-4
GO:0044029 hypomethylation of CpG island 6.971113e-4
GO:0043932 ossification involved in bone remodeling 6.989482e-4
GO:0060547 negative regulation of necrotic cell death 7.426251e-4
GO:0000738 DNA catabolic process, exonucleolytic 7.426251e-4
GO:0045124 regulation of bone resorption 7.978731e-4
GO:0048486 parasympathetic nervous system development 8.188963e-4
GO:0044341 sodium-dependent phosphate transport 8.437374e-4
GO:0042663 regulation of endodermal cell fate specification 8.437374e-4
GO:0070875 positive regulation of glycogen metabolic process 8.665000e-4
GO:0007096 regulation of exit from mitosis 8.841342e-4
GO:0019229 regulation of vasoconstriction 8.981256e-4
GO:0035021 negative regulation of Rac protein signal transduction 9.106250e-4
GO:0060193 positive regulation of lipase activity 9.299956e-4
GO:0006368 transcription elongation from RNA polymerase II promoter 9.457298e-4
GO:0034393 positive regulation of smooth muscle cell apoptosis 9.841688e-4
GO:0071243 cellular response to arsenic-containing substance 9.922644e-4
GO:0008634 negative regulation of survival gene product expression 9.957534e-4
GO:0022614 membrane to membrane docking 9.957534e-4
GO:0051388 positive regulation of nerve growth factor receptor signaling pathway 9.961671e-4
GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing 9.961671e-4
GO:0010273 detoxification of copper ion 9.961671e-4
GO:0006206 pyrimidine base metabolic process 1.002421e-3
GO:0090179 planar cell polarity pathway involved in neural tube closure 1.005819e-3
GO:0014912 negative regulation of smooth muscle cell migration 1.037893e-3
GO:0015840 urea transport 1.062037e-3
GO:0051604 protein maturation 1.100277e-3
GO:0033085 negative regulation of T cell differentiation in thymus 1.109140e-3
GO:0016142 O-glycoside catabolic process 1.114979e-3
GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 1.114979e-3
GO:0045620 negative regulation of lymphocyte differentiation 1.134920e-3
GO:0006378 mRNA polyadenylation 1.151650e-3
GO:0010390 histone monoubiquitination 1.153687e-3
GO:0032964 collagen biosynthetic process 1.193627e-3
GO:0060379 cardiac muscle cell myoblast differentiation 1.217087e-3
GO:0061077 chaperone-mediated protein folding 1.248820e-3
GO:0060744 mammary gland branching involved in thelarche 1.253402e-3
GO:0043279 response to alkaloid 1.280017e-3
GO:0032233 positive regulation of actin filament bundle assembly 1.283499e-3
GO:0031124 mRNA 3'-end processing 1.296123e-3
GO:0060326 cell chemotaxis 1.299924e-3
GO:0010936 negative regulation of macrophage cytokine production 1.308877e-3
GO:0006003 fructose 2,6-bisphosphate metabolic process 1.309969e-3
GO:0006734 NADH metabolic process 1.411206e-3
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 1.435509e-3
GO:0032218 riboflavin transport 1.435509e-3
GO:0007283 spermatogenesis 1.466232e-3
GO:0009303 rRNA transcription 1.505286e-3
GO:0007281 germ cell development 1.522891e-3
GO:0002903 negative regulation of B cell apoptosis 1.537894e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 1.562675e-3
GO:0006409 tRNA export from nucleus 1.562675e-3
GO:0048632 negative regulation of skeletal muscle tissue growth 1.562675e-3
GO:0018206 peptidyl-methionine modification 1.575255e-3
GO:0043627 response to estrogen stimulus 1.606540e-3
GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway 1.606820e-3
GO:0002069 columnar/cuboidal epithelial cell maturation 1.619109e-3
GO:0051905 establishment of pigment granule localization 1.681005e-3
GO:0035066 positive regulation of histone acetylation 1.938136e-3
GO:0001558 regulation of cell growth 1.938174e-3
GO:0048268 clathrin coat assembly 1.940725e-3
GO:0051272 positive regulation of cellular component movement 1.966458e-3
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent 1.995956e-3
GO:0021783 preganglionic parasympathetic nervous system development 1.996058e-3
GO:0010660 regulation of muscle cell apoptosis 2.015337e-3
GO:0002082 regulation of oxidative phosphorylation 2.045117e-3
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 2.072916e-3
GO:0046850 regulation of bone remodeling 2.117287e-3
GO:0032863 activation of Rac GTPase activity 2.145664e-3
GO:0006301 postreplication repair 2.153671e-3
GO:0060351 cartilage development involved in endochondral bone morphogenesis 2.160693e-3
GO:0042482 positive regulation of odontogenesis 2.202736e-3
GO:0071257 cellular response to electrical stimulus 2.227876e-3
GO:0072529 pyrimidine-containing compound catabolic process 2.234947e-3
GO:0006855 drug transmembrane transport 2.275775e-3
GO:0032869 cellular response to insulin stimulus 2.341783e-3
GO:0006901 vesicle coating 2.410515e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 2.526187e-3
GO:0021542 dentate gyrus development 2.570950e-3
GO:0002449 lymphocyte mediated immunity 2.584034e-3
GO:0032241 positive regulation of nucleobase-containing compound transport 2.630779e-3
GO:0035886 vascular smooth muscle cell differentiation 2.657937e-3
GO:2000278 regulation of DNA biosynthetic process 2.665695e-3
GO:0006956 complement activation 2.677880e-3
GO:0060986 endocrine hormone secretion 2.684981e-3
GO:0034105 positive regulation of tissue remodeling 2.700531e-3
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 2.706572e-3
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 2.706572e-3
GO:0045128 negative regulation of reciprocal meiotic recombination 2.706572e-3
GO:0006311 meiotic gene conversion 2.706572e-3
GO:0034337 RNA folding 2.793026e-3
GO:0032276 regulation of gonadotropin secretion 2.812561e-3
GO:0035814 negative regulation of renal sodium excretion 2.812699e-3
GO:0034767 positive regulation of ion transmembrane transport 2.863629e-3
GO:0031638 zymogen activation 2.863629e-3
GO:0033604 negative regulation of catecholamine secretion 2.881814e-3
GO:0010763 positive regulation of fibroblast migration 2.881814e-3
GO:0032401 establishment of melanosome localization 2.903269e-3
GO:0090096 positive regulation of metanephric cap mesenchymal cell proliferation 2.960677e-3
GO:0045773 positive regulation of axon extension 3.028020e-3
GO:0006878 cellular copper ion homeostasis 3.059381e-3
GO:0031954 positive regulation of protein autophosphorylation 3.065821e-3
GO:0050868 negative regulation of T cell activation 3.090541e-3
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 3.376911e-3
GO:0002268 follicular dendritic cell differentiation 3.376911e-3
GO:0009404 toxin metabolic process 3.412777e-3
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 3.525632e-3
GO:0032836 glomerular basement membrane development 3.525632e-3
GO:0015670 carbon dioxide transport 3.525632e-3
GO:0006265 DNA topological change 3.525632e-3
GO:0032642 regulation of chemokine production 3.569180e-3
GO:0042088 T-helper 1 type immune response 3.597678e-3
GO:0021563 glossopharyngeal nerve development 3.632583e-3
GO:0090218 positive regulation of lipid kinase activity 3.671492e-3
GO:0045927 positive regulation of growth 3.689863e-3
GO:0060324 face development 3.751254e-3
GO:0060948 cardiac vascular smooth muscle cell development 3.985833e-3
GO:0043117 positive regulation of vascular permeability 3.985833e-3
GO:0033628 regulation of cell adhesion mediated by integrin 3.990254e-3
GO:0050714 positive regulation of protein secretion 4.009314e-3
GO:0045988 negative regulation of striated muscle contraction 4.083128e-3
GO:0014805 smooth muscle adaptation 4.126823e-3
GO:0035674 tricarboxylic acid transmembrane transport 4.126823e-3
GO:0009314 response to radiation 4.151044e-3
GO:0046475 glycerophospholipid catabolic process 4.281679e-3
GO:0071217 cellular response to external biotic stimulus 4.343452e-3
GO:0072249 metanephric glomerular visceral epithelial cell development 4.343452e-3
GO:0072274 metanephric glomerular basement membrane development 4.343452e-3
GO:0048677 axon extension involved in regeneration 4.343452e-3
GO:0042700 luteinizing hormone signaling pathway 4.343452e-3
GO:0017187 peptidyl-glutamic acid carboxylation 4.343452e-3
GO:0021933 radial glia guided migration of cerebellar granule cell 4.343452e-3
GO:0002542 Factor XII activation 4.343452e-3
GO:0032700 negative regulation of interleukin-17 production 4.370615e-3
GO:0032229 negative regulation of synaptic transmission, GABAergic 4.370615e-3
GO:0046626 regulation of insulin receptor signaling pathway 4.406596e-3
GO:0002902 regulation of B cell apoptosis 4.425222e-3
GO:0061383 trabecula morphogenesis 4.427388e-3
GO:0006817 phosphate ion transport 4.449784e-3
GO:0032892 positive regulation of organic acid transport 4.449784e-3
GO:0071870 cellular response to catecholamine stimulus 4.482051e-3
GO:0043923 positive regulation by host of viral transcription 4.610597e-3
GO:0090324 negative regulation of oxidative phosphorylation 4.883491e-3
GO:0000379 tRNA-type intron splice site recognition and cleavage 4.883491e-3
GO:0015761 mannose transport 4.883491e-3
GO:0010756 positive regulation of plasminogen activation 4.883491e-3
GO:0010255 glucose mediated signaling pathway 4.883491e-3
GO:0097039 protein linear polyubiquitination 4.899328e-3
GO:0016098 monoterpenoid metabolic process 4.899328e-3
GO:0002536 respiratory burst involved in inflammatory response 4.916910e-3
GO:0048242 epinephrine secretion 4.924319e-3
GO:0051302 regulation of cell division 4.965399e-3
GO:0097084 vascular smooth muscle cell development 4.966985e-3
GO:0043248 proteasome assembly 4.966985e-3
GO:0032714 negative regulation of interleukin-5 production 4.991583e-3
GO:0051135 positive regulation of NK T cell activation 4.995461e-3
GO:0032722 positive regulation of chemokine production 4.999989e-3
GO:0006308 DNA catabolic process 5.070880e-3
GO:0060160 negative regulation of dopamine receptor signaling pathway 5.082698e-3
GO:0015746 citrate transport 5.082698e-3
GO:0007041 lysosomal transport 5.153891e-3
GO:0014895 smooth muscle hypertrophy 5.258815e-3
GO:0032065 cortical protein anchoring 5.258815e-3
GO:0003106 negative regulation of glomerular filtration by angiotensin 5.258815e-3
GO:0010976 positive regulation of neuron projection development 5.304800e-3
GO:0051148 negative regulation of muscle cell differentiation 5.372969e-3
GO:0032277 negative regulation of gonadotropin secretion 5.374312e-3
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 5.523775e-3
GO:0032274 gonadotropin secretion 5.523775e-3
GO:0001569 patterning of blood vessels 5.531074e-3
GO:0042129 regulation of T cell proliferation 5.569965e-3
GO:0021564 vagus nerve development 5.589446e-3
GO:0005979 regulation of glycogen biosynthetic process 5.639753e-3
GO:0070305 response to cGMP 5.754613e-3
GO:0016559 peroxisome fission 5.855816e-3
GO:2001020 regulation of response to DNA damage stimulus 5.865547e-3
GO:0032696 negative regulation of interleukin-13 production 6.031413e-3
GO:0060343 trabecula formation 6.101500e-3
GO:0050766 positive regulation of phagocytosis 6.158931e-3
GO:0035767 endothelial cell chemotaxis 6.171125e-3
GO:0060322 head development 6.214384e-3
GO:0071157 negative regulation of cell cycle arrest 6.290608e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 6.291153e-3
GO:0006910 phagocytosis, recognition 6.315635e-3
GO:0033133 positive regulation of glucokinase activity 6.420225e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 6.536626e-3
GO:0060913 cardiac cell fate determination 6.634277e-3
GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 6.642367e-3
GO:0020027 hemoglobin metabolic process 6.686394e-3
GO:0045626 negative regulation of T-helper 1 cell differentiation 6.724502e-3
GO:0010845 positive regulation of reciprocal meiotic recombination 6.724502e-3
GO:0000238 zygotene 6.724502e-3
GO:0010661 positive regulation of muscle cell apoptosis 6.916641e-3
GO:0008210 estrogen metabolic process 6.940257e-3
GO:0042744 hydrogen peroxide catabolic process 7.156645e-3
GO:0032231 regulation of actin filament bundle assembly 7.214486e-3
GO:0035813 regulation of renal sodium excretion 7.470373e-3
GO:0046880 regulation of follicle-stimulating hormone secretion 7.566781e-3
GO:0048630 skeletal muscle tissue growth 7.566781e-3
GO:0045683 negative regulation of epidermis development 7.726193e-3
GO:0070537 histone H2A K63-linked deubiquitination 7.744662e-3
GO:0042396 phosphagen biosynthetic process 7.744662e-3
GO:0033159 negative regulation of protein import into nucleus, translocation 7.744662e-3
GO:0045730 respiratory burst 7.795072e-3
GO:0032868 response to insulin stimulus 7.919303e-3
GO:0009411 response to UV 7.926137e-3
GO:0030263 apoptotic chromosome condensation 7.951170e-3
GO:0051586 positive regulation of dopamine uptake 7.951170e-3
GO:0010518 positive regulation of phospholipase activity 8.022180e-3
GO:0021993 initiation of neural tube closure 8.107402e-3
GO:0010511 regulation of phosphatidylinositol biosynthetic process 8.107402e-3
GO:0030223 neutrophil differentiation 8.142707e-3
GO:0033602 negative regulation of dopamine secretion 8.364079e-3
GO:2000191 regulation of fatty acid transport 8.451813e-3
GO:0051131 chaperone-mediated protein complex assembly 8.530299e-3
GO:0090002 establishment of protein localization in plasma membrane 8.530299e-3
GO:0010569 regulation of double-strand break repair via homologous recombination 8.547029e-3
GO:0090280 positive regulation of calcium ion import 8.620116e-3
GO:0006102 isocitrate metabolic process 8.620116e-3
GO:2000108 positive regulation of leukocyte apoptosis 8.804002e-3
GO:0033566 gamma-tubulin complex localization 8.836624e-3
GO:0031627 telomeric loop formation 8.836624e-3
GO:0061302 smooth muscle cell-matrix adhesion 8.836624e-3
GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning 8.836624e-3
GO:0016068 type I hypersensitivity 8.836624e-3
GO:0018230 peptidyl-L-cysteine S-palmitoylation 8.836624e-3
GO:0006782 protoporphyrinogen IX biosynthetic process 8.988159e-3
GO:0006273 lagging strand elongation 8.988159e-3
GO:0043951 negative regulation of cAMP-mediated signaling 9.005059e-3
GO:0015793 glycerol transport 9.005059e-3
GO:0010991 negative regulation of SMAD protein complex assembly 9.005059e-3
GO:0019058 viral infectious cycle 9.083360e-3
GO:0002385 mucosal immune response 9.171290e-3
GO:0010667 negative regulation of cardiac muscle cell apoptosis 9.200388e-3
GO:0019835 cytolysis 9.512339e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 9.679752e-3
GO:0035441 cell migration involved in vasculogenesis 9.824546e-3
GO:0002251 organ or tissue specific immune response 1.026786e-2
GO:0055070 copper ion homeostasis 1.026786e-2
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 1.034733e-2
GO:0046890 regulation of lipid biosynthetic process 1.038783e-2
GO:0071321 cellular response to cGMP 1.043854e-2
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1.043854e-2
GO:0001765 membrane raft assembly 1.043854e-2
GO:0033081 regulation of T cell differentiation in thymus 1.064573e-2
GO:0010717 regulation of epithelial to mesenchymal transition 1.072704e-2
GO:0048241 epinephrine transport 1.076077e-2
GO:0051590 positive regulation of neurotransmitter transport 1.076941e-2
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1.082646e-2
GO:0046092 deoxycytidine metabolic process 1.082733e-2
GO:0003094 glomerular filtration 1.082733e-2
GO:0002575 basophil chemotaxis 1.082733e-2
GO:0002432 granuloma formation 1.082733e-2
GO:0034619 cellular chaperone-mediated protein complex assembly 1.087702e-2
GO:0051875 pigment granule localization 1.102407e-2
GO:2000484 positive regulation of interleukin-8 secretion 1.116646e-2
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 1.116798e-2
GO:0060375 regulation of mast cell differentiation 1.133625e-2
GO:0071247 cellular response to chromate 1.146583e-2
GO:0071881 inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway 1.146583e-2
GO:0071882 activation of phospholipase C activity by adrenergic receptor signaling pathway 1.146583e-2
GO:0032900 negative regulation of neurotrophin production 1.146583e-2
GO:0000059 protein import into nucleus, docking 1.146583e-2
GO:0010760 negative regulation of macrophage chemotaxis 1.146583e-2
GO:0018214 protein carboxylation 1.146583e-2
GO:0032244 positive regulation of nucleoside transport 1.146583e-2
GO:0019067 viral assembly, maturation, egress, and release 1.157976e-2
GO:0008333 endosome to lysosome transport 1.196573e-2
GO:0043631 RNA polyadenylation 1.217080e-2
GO:0050760 negative regulation of thymidylate synthase biosynthetic process 1.218280e-2
GO:0043137 DNA replication, removal of RNA primer 1.218280e-2
GO:0007174 epidermal growth factor catabolic process 1.218280e-2
GO:0015732 prostaglandin transport 1.218280e-2
GO:0010740 positive regulation of intracellular protein kinase cascade 1.229793e-2
GO:0006099 tricarboxylic acid cycle 1.237961e-2
GO:0032846 positive regulation of homeostatic process 1.240033e-2
GO:0060159 regulation of dopamine receptor signaling pathway 1.240406e-2
GO:0051006 positive regulation of lipoprotein lipase activity 1.241047e-2
GO:0045647 negative regulation of erythrocyte differentiation 1.241047e-2
GO:0006626 protein targeting to mitochondrion 1.252549e-2
GO:0051954 positive regulation of amine transport 1.258515e-2
GO:0048013 ephrin receptor signaling pathway 1.271267e-2
GO:0032606 type I interferon production 1.281051e-2
GO:0033137 negative regulation of peptidyl-serine phosphorylation 1.306819e-2
GO:0043467 regulation of generation of precursor metabolites and energy 1.309033e-2
GO:0050863 regulation of T cell activation 1.309920e-2
GO:0022616 DNA strand elongation 1.332672e-2
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1.342709e-2
GO:0009062 fatty acid catabolic process 1.358055e-2
GO:0050432 catecholamine secretion 1.360374e-2
GO:0043921 modulation by host of viral transcription 1.374241e-2
GO:0009914 hormone transport 1.396391e-2
GO:0032228 regulation of synaptic transmission, GABAergic 1.396776e-2
GO:0034103 regulation of tissue remodeling 1.400718e-2
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.409307e-2
GO:0050917 sensory perception of umami taste 1.409307e-2
GO:0032784 regulation of transcription elongation, DNA-dependent 1.422005e-2
GO:0048545 response to steroid hormone stimulus 1.422726e-2
GO:0045835 negative regulation of meiosis 1.428245e-2
GO:0045358 negative regulation of interferon-beta biosynthetic process 1.449916e-2
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway 1.449916e-2
GO:0021586 pons maturation 1.449916e-2
GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.452439e-2
GO:0090150 establishment of protein localization in membrane 1.457482e-2
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 1.460907e-2
GO:0046544 development of secondary male sexual characteristics 1.460907e-2
GO:0044342 type B pancreatic cell proliferation 1.479412e-2
GO:0042996 regulation of Golgi to plasma membrane protein transport 1.479412e-2
GO:0008298 intracellular mRNA localization 1.479412e-2
GO:0030321 transepithelial chloride transport 1.481595e-2
GO:0006991 response to sterol depletion 1.481595e-2
GO:0051492 regulation of stress fiber assembly 1.488638e-2
GO:0014707 branchiomeric skeletal muscle development 1.492103e-2
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 1.492103e-2
GO:0032849 positive regulation of cellular pH reduction 1.499115e-2
GO:0045332 phospholipid translocation 1.506801e-2
GO:0010700 negative regulation of norepinephrine secretion 1.506801e-2
GO:0040009 regulation of growth rate 1.506801e-2
GO:0050909 sensory perception of taste 1.507102e-2
GO:0051096 positive regulation of helicase activity 1.508248e-2
GO:0001835 blastocyst hatching 1.508248e-2
GO:0045116 protein neddylation 1.508248e-2
GO:0043088 regulation of Cdc42 GTPase activity 1.520094e-2
GO:0019218 regulation of steroid metabolic process 1.523976e-2
GO:0035025 positive regulation of Rho protein signal transduction 1.575669e-2
GO:0050768 negative regulation of neurogenesis 1.597822e-2
GO:0006635 fatty acid beta-oxidation 1.602289e-2
GO:0014819 regulation of skeletal muscle contraction 1.603533e-2
GO:0032855 positive regulation of Rac GTPase activity 1.607901e-2
GO:0034616 response to laminar fluid shear stress 1.616052e-2
GO:0006670 sphingosine metabolic process 1.617063e-2
GO:0046113 nucleobase catabolic process 1.621820e-2