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Novel motif:57

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name:motif57_AGGCAT

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0050896 response to stimulus 1.708526e-24
GO:0032501 multicellular organismal process 5.018302e-23
GO:0051179 localization 7.533502e-23
GO:0007154 cell communication 1.404220e-21
GO:0051716 cellular response to stimulus 1.707766e-21
GO:0051234 establishment of localization 4.837354e-20
GO:0006810 transport 8.596069e-20
GO:0023052 signaling 1.448875e-18
GO:0065008 regulation of biological quality 5.150781e-18
GO:0006811 ion transport 1.004446e-16
GO:0071840 cellular component organization or biogenesis 2.927484e-16
GO:0006950 response to stress 3.539735e-16
GO:0016043 cellular component organization 1.013006e-15
GO:0007165 signal transduction 7.857081e-15
GO:0006629 lipid metabolic process 1.038699e-14
GO:0032502 developmental process 2.184585e-14
GO:0032879 regulation of localization 2.416178e-14
GO:0044085 cellular component biogenesis 2.501753e-14
GO:0006812 cation transport 3.535441e-14
GO:0019836 hemolysis by symbiont of host erythrocytes 4.696297e-14
GO:0048856 anatomical structure development 7.725356e-14
GO:0022607 cellular component assembly 1.816604e-13
GO:0044281 small molecule metabolic process 2.953302e-13
GO:0043933 macromolecular complex subunit organization 3.883030e-13
GO:0009987 cellular process 6.877534e-13
GO:0051883 killing of cells in other organism involved in symbiotic interaction 9.950272e-13
GO:0007525 somatic muscle development 1.109125e-12
GO:0002376 immune system process 1.122349e-12
GO:0003008 system process 1.292479e-12
GO:0010033 response to organic substance 1.710492e-12
GO:0065007 biological regulation 2.035629e-12
GO:0006082 organic acid metabolic process 2.746024e-12
GO:0007155 cell adhesion 4.169707e-12
GO:0042180 cellular ketone metabolic process 4.493206e-12
GO:0051259 protein oligomerization 6.162969e-12
GO:0019752 carboxylic acid metabolic process 9.623114e-12
GO:0065003 macromolecular complex assembly 1.226770e-11
GO:0051336 regulation of hydrolase activity 1.492740e-11
GO:0048518 positive regulation of biological process 2.249816e-11
GO:0010941 regulation of cell death 3.502814e-11
GO:0007275 multicellular organismal development 4.790849e-11
GO:0051704 multi-organism process 5.058518e-11
GO:0048519 negative regulation of biological process 6.017946e-11
GO:0007166 cell surface receptor linked signaling pathway 7.805280e-11
GO:0010876 lipid localization 1.083969e-10
GO:0030001 metal ion transport 1.345712e-10
GO:0048514 blood vessel morphogenesis 1.363854e-10
GO:0048731 system development 2.177276e-10
GO:0050789 regulation of biological process 3.137483e-10
GO:0048075 positive regulation of eye pigmentation 4.503494e-10
GO:0051049 regulation of transport 4.723470e-10
GO:0048608 reproductive structure development 5.197052e-10
GO:0044255 cellular lipid metabolic process 6.124157e-10
GO:0043067 regulation of programmed cell death 6.292235e-10
GO:0071622 regulation of granulocyte chemotaxis 6.444962e-10
GO:0009617 response to bacterium 8.595580e-10
GO:0070482 response to oxygen levels 9.929314e-10
GO:0010038 response to metal ion 1.080801e-9
GO:0046661 male sex differentiation 1.182211e-9
GO:0010035 response to inorganic substance 1.354500e-9
GO:0046546 development of primary male sexual characteristics 1.457355e-9
GO:0010758 regulation of macrophage chemotaxis 1.582309e-9
GO:0032320 positive regulation of Ras GTPase activity 1.637779e-9
GO:0035556 intracellular signal transduction 1.640158e-9
GO:0070555 response to interleukin-1 1.651522e-9
GO:0044106 cellular amine metabolic process 1.737907e-9
GO:0010759 positive regulation of macrophage chemotaxis 1.902477e-9
GO:0006952 defense response 2.063451e-9
GO:0048522 positive regulation of cellular process 2.806715e-9
GO:0042981 regulation of apoptosis 2.952265e-9
GO:0010565 regulation of cellular ketone metabolic process 3.973403e-9
GO:0007584 response to nutrient 4.820569e-9
GO:0048523 negative regulation of cellular process 4.887537e-9
GO:0032318 regulation of Ras GTPase activity 5.121292e-9
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 5.186511e-9
GO:0042221 response to chemical stimulus 6.473617e-9
GO:0071675 regulation of mononuclear cell migration 6.572982e-9
GO:0048073 regulation of eye pigmentation 6.673065e-9
GO:0045616 regulation of keratinocyte differentiation 6.955937e-9
GO:0008584 male gonad development 7.767177e-9
GO:0012501 programmed cell death 7.960479e-9
GO:0022414 reproductive process 8.649023e-9
GO:0048513 organ development 1.108989e-8
GO:0000003 reproduction 1.110339e-8
GO:0042157 lipoprotein metabolic process 1.144765e-8
GO:0009566 fertilization 1.225640e-8
GO:0032571 response to vitamin K 1.281598e-8
GO:0048878 chemical homeostasis 1.604529e-8
GO:0045604 regulation of epidermal cell differentiation 1.624903e-8
GO:0030301 cholesterol transport 1.636466e-8
GO:0016265 death 1.645662e-8
GO:0043087 regulation of GTPase activity 1.717850e-8
GO:0050801 ion homeostasis 1.722517e-8
GO:0042127 regulation of cell proliferation 1.734363e-8
GO:0009611 response to wounding 1.797518e-8
GO:0009628 response to abiotic stimulus 1.938071e-8
GO:0008219 cell death 2.031426e-8
GO:0001666 response to hypoxia 2.139787e-8
GO:0051239 regulation of multicellular organismal process 2.253370e-8
GO:0071822 protein complex subunit organization 2.334996e-8
GO:0006955 immune response 3.052522e-8
GO:0006869 lipid transport 3.087307e-8
GO:0043269 regulation of ion transport 3.201718e-8
GO:0033124 regulation of GTP catabolic process 3.354927e-8
GO:0008202 steroid metabolic process 3.538671e-8
GO:0051262 protein tetramerization 3.548664e-8
GO:0072507 divalent inorganic cation homeostasis 3.695996e-8
GO:0060047 heart contraction 3.995189e-8
GO:0006915 apoptosis 4.084009e-8
GO:0009653 anatomical structure morphogenesis 4.259972e-8
GO:0032940 secretion by cell 4.355339e-8
GO:0030101 natural killer cell activation 4.395041e-8
GO:0015918 sterol transport 4.813795e-8
GO:0007296 vitellogenesis 4.899051e-8
GO:0031667 response to nutrient levels 5.110197e-8
GO:0009888 tissue development 5.508045e-8
GO:0015721 bile acid and bile salt transport 5.707239e-8
GO:0032269 negative regulation of cellular protein metabolic process 5.840686e-8
GO:0051345 positive regulation of hydrolase activity 5.990104e-8
GO:0045137 development of primary sexual characteristics 6.065129e-8
GO:0070278 extracellular matrix constituent secretion 6.608052e-8
GO:0010260 organ senescence 6.608052e-8
GO:0019216 regulation of lipid metabolic process 7.343910e-8
GO:0009308 amine metabolic process 7.489885e-8
GO:0050790 regulation of catalytic activity 7.629024e-8
GO:0044093 positive regulation of molecular function 7.870053e-8
GO:0016559 peroxisome fission 8.193569e-8
GO:0071702 organic substance transport 8.499930e-8
GO:0042158 lipoprotein biosynthetic process 8.539297e-8
GO:0009894 regulation of catabolic process 9.418995e-8
GO:0031329 regulation of cellular catabolic process 9.532019e-8
GO:0048583 regulation of response to stimulus 9.553149e-8
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 9.905997e-8
GO:0014823 response to activity 1.032500e-7
GO:0010269 response to selenium ion 1.068947e-7
GO:0051246 regulation of protein metabolic process 1.116598e-7
GO:0008406 gonad development 1.160327e-7
GO:0055074 calcium ion homeostasis 1.172573e-7
GO:0051385 response to mineralocorticoid stimulus 1.216698e-7
GO:0006928 cellular component movement 1.253253e-7
GO:0032868 response to insulin stimulus 1.282468e-7
GO:0051260 protein homooligomerization 1.305577e-7
GO:0072503 cellular divalent inorganic cation homeostasis 1.366079e-7
GO:0008015 blood circulation 1.378248e-7
GO:0007028 cytoplasm organization 1.410650e-7
GO:0032026 response to magnesium ion 1.429198e-7
GO:0050877 neurological system process 1.432611e-7
GO:0007267 cell-cell signaling 1.449940e-7
GO:0006874 cellular calcium ion homeostasis 1.515154e-7
GO:0070887 cellular response to chemical stimulus 1.643639e-7
GO:0070541 response to platinum ion 1.665460e-7
GO:0006873 cellular ion homeostasis 1.700829e-7
GO:0034097 response to cytokine stimulus 1.749670e-7
GO:0043085 positive regulation of catalytic activity 1.811876e-7
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 1.883015e-7
GO:0006520 cellular amino acid metabolic process 1.941241e-7
GO:0051056 regulation of small GTPase mediated signal transduction 2.070476e-7
GO:0006461 protein complex assembly 2.180474e-7
GO:0055065 metal ion homeostasis 2.468132e-7
GO:0001944 vasculature development 2.569102e-7
GO:0030334 regulation of cell migration 2.668978e-7
GO:0031640 killing of cells of other organism 2.971366e-7
GO:0006140 regulation of nucleotide metabolic process 3.107122e-7
GO:0010648 negative regulation of cell communication 3.111392e-7
GO:0048585 negative regulation of response to stimulus 3.117611e-7
GO:0051248 negative regulation of protein metabolic process 3.118350e-7
GO:0023057 negative regulation of signaling 3.170741e-7
GO:0003012 muscle system process 3.261394e-7
GO:0006875 cellular metal ion homeostasis 3.267181e-7
GO:0055080 cation homeostasis 3.276118e-7
GO:0001568 blood vessel development 3.431499e-7
GO:0009607 response to biotic stimulus 3.913544e-7
GO:0050878 regulation of body fluid levels 3.965763e-7
GO:0070271 protein complex biogenesis 3.976290e-7
GO:0008217 regulation of blood pressure 4.010693e-7
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 4.031440e-7
GO:0046903 secretion 4.103769e-7
GO:0060571 morphogenesis of an epithelial fold 4.151344e-7
GO:0060048 cardiac muscle contraction 4.216440e-7
GO:0010942 positive regulation of cell death 4.306892e-7
GO:0048870 cell motility 4.519669e-7
GO:0032787 monocarboxylic acid metabolic process 5.228355e-7
GO:0043069 negative regulation of programmed cell death 5.268029e-7
GO:0033121 regulation of purine nucleotide catabolic process 5.586795e-7
GO:0043316 cytotoxic T cell degranulation 5.715558e-7
GO:0015672 monovalent inorganic cation transport 5.721197e-7
GO:0051659 maintenance of mitochondrion location 5.990799e-7
GO:0033273 response to vitamin 6.186964e-7
GO:0009968 negative regulation of signal transduction 6.202624e-7
GO:0006936 muscle contraction 6.240694e-7
GO:0007186 G-protein coupled receptor protein signaling pathway 6.815342e-7
GO:0003374 dynamin polymerization involved in mitochondrial fission 6.836143e-7
GO:0090149 membrane fission involved in mitochondrial fission 6.836143e-7
GO:0070318 positive regulation of G0 to G1 transition 6.889956e-7
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 7.950997e-7
GO:0006916 anti-apoptosis 8.114081e-7
GO:0042310 vasoconstriction 8.662308e-7
GO:0042537 benzene-containing compound metabolic process 8.740717e-7
GO:0051649 establishment of localization in cell 8.876942e-7
GO:2000145 regulation of cell motility 8.955785e-7
GO:0030193 regulation of blood coagulation 9.539951e-7
GO:0032268 regulation of cellular protein metabolic process 9.974976e-7
GO:0040012 regulation of locomotion 1.007756e-6
GO:0048660 regulation of smooth muscle cell proliferation 1.071204e-6
GO:0051707 response to other organism 1.157255e-6
GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 1.169312e-6
GO:0055082 cellular chemical homeostasis 1.189121e-6
GO:0051271 negative regulation of cellular component movement 1.193175e-6
GO:0031960 response to corticosteroid stimulus 1.203125e-6
GO:0034381 plasma lipoprotein particle clearance 1.210037e-6
GO:0061024 membrane organization 1.241218e-6
GO:0048661 positive regulation of smooth muscle cell proliferation 1.254186e-6
GO:0009725 response to hormone stimulus 1.268099e-6
GO:0050820 positive regulation of coagulation 1.268884e-6
GO:0019217 regulation of fatty acid metabolic process 1.272403e-6
GO:0032101 regulation of response to external stimulus 1.274984e-6
GO:0030003 cellular cation homeostasis 1.412495e-6
GO:0044283 small molecule biosynthetic process 1.423440e-6
GO:0009719 response to endogenous stimulus 1.436443e-6
GO:0050818 regulation of coagulation 1.470279e-6
GO:0018958 phenol-containing compound metabolic process 1.470458e-6
GO:0060548 negative regulation of cell death 1.537207e-6
GO:0070316 regulation of G0 to G1 transition 1.572943e-6
GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1.588945e-6
GO:0051270 regulation of cellular component movement 1.628118e-6
GO:0045682 regulation of epidermis development 1.631546e-6
GO:0043066 negative regulation of apoptosis 1.638234e-6
GO:0035150 regulation of tube size 1.711706e-6
GO:0007268 synaptic transmission 1.727113e-6
GO:0050880 regulation of blood vessel size 1.752317e-6
GO:0050794 regulation of cellular process 1.766709e-6
GO:0016192 vesicle-mediated transport 2.062855e-6
GO:0061084 negative regulation of protein refolding 2.133425e-6
GO:2000026 regulation of multicellular organismal development 2.225393e-6
GO:0016044 cellular membrane organization 2.365653e-6
GO:0003018 vascular process in circulatory system 2.417783e-6
GO:0052547 regulation of peptidase activity 2.440503e-6
GO:0033993 response to lipid 2.574632e-6
GO:0019226 transmission of nerve impulse 2.593886e-6
GO:0009991 response to extracellular stimulus 2.676870e-6
GO:0006222 UMP biosynthetic process 2.802719e-6
GO:0042060 wound healing 2.821571e-6
GO:0043547 positive regulation of GTPase activity 2.825118e-6
GO:0016998 cell wall macromolecule catabolic process 2.837120e-6
GO:0003013 circulatory system process 2.915740e-6
GO:0006575 cellular modified amino acid metabolic process 3.008213e-6
GO:0030154 cell differentiation 3.123106e-6
GO:0007548 sex differentiation 3.147369e-6
GO:0001525 angiogenesis 3.159987e-6
GO:0051384 response to glucocorticoid stimulus 3.389438e-6
GO:0010594 regulation of endothelial cell migration 3.575891e-6
GO:0006911 phagocytosis, engulfment 3.595206e-6
GO:0007596 blood coagulation 3.598182e-6
GO:0010955 negative regulation of protein processing 3.662258e-6
GO:0006642 triglyceride mobilization 3.714184e-6
GO:0003006 developmental process involved in reproduction 3.745168e-6
GO:0032914 positive regulation of transforming growth factor beta1 production 3.780635e-6
GO:0065009 regulation of molecular function 3.810291e-6
GO:0050793 regulation of developmental process 3.866079e-6
GO:0019538 protein metabolic process 4.196399e-6
GO:0071379 cellular response to prostaglandin stimulus 4.231041e-6
GO:0034374 low-density lipoprotein particle remodeling 4.504714e-6
GO:0032103 positive regulation of response to external stimulus 4.670746e-6
GO:0000245 spliceosome assembly 4.753628e-6
GO:0021509 roof plate formation 4.755024e-6
GO:0043101 purine-containing compound salvage 4.926919e-6
GO:0010817 regulation of hormone levels 5.211092e-6
GO:0072358 cardiovascular system development 5.462119e-6
GO:0046464 acylglycerol catabolic process 5.545199e-6
GO:0048646 anatomical structure formation involved in morphogenesis 5.552348e-6
GO:0007599 hemostasis 5.612291e-6
GO:0019827 stem cell maintenance 5.737856e-6
GO:0007565 female pregnancy 5.914082e-6
GO:0023051 regulation of signaling 5.964658e-6
GO:0016525 negative regulation of angiogenesis 6.037690e-6
GO:0051235 maintenance of location 6.444187e-6
GO:0071842 cellular component organization at cellular level 6.638709e-6
GO:0010595 positive regulation of endothelial cell migration 6.747300e-6
GO:0033194 response to hydroperoxide 6.755951e-6
GO:0071841 cellular component organization or biogenesis at cellular level 6.902688e-6
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.014411e-6
GO:0019433 triglyceride catabolic process 7.076845e-6
GO:0048468 cell development 7.199029e-6
GO:0048869 cellular developmental process 7.221041e-6
GO:2000146 negative regulation of cell motility 7.221935e-6
GO:0033554 cellular response to stress 7.270332e-6
GO:0051093 negative regulation of developmental process 7.395377e-6
GO:0009966 regulation of signal transduction 7.539535e-6
GO:0014889 muscle atrophy 7.766365e-6
GO:0090066 regulation of anatomical structure size 7.781618e-6
GO:0016477 cell migration 8.078757e-6
GO:0006214 thymidine catabolic process 8.191446e-6
GO:0002237 response to molecule of bacterial origin 8.681366e-6
GO:0042119 neutrophil activation 9.023272e-6
GO:0045765 regulation of angiogenesis 9.393200e-6
GO:0046503 glycerolipid catabolic process 9.760078e-6
GO:0046104 thymidine metabolic process 9.860173e-6
GO:0048609 multicellular organismal reproductive process 9.864351e-6
GO:0032924 activin receptor signaling pathway 9.964595e-6
GO:0002090 regulation of receptor internalization 9.991513e-6
GO:0006518 peptide metabolic process 1.002099e-5
GO:0010631 epithelial cell migration 1.013715e-5
GO:0072593 reactive oxygen species metabolic process 1.018077e-5
GO:0044267 cellular protein metabolic process 1.029934e-5
GO:0002690 positive regulation of leukocyte chemotaxis 1.030944e-5
GO:0032496 response to lipopolysaccharide 1.038907e-5
GO:0044036 cell wall macromolecule metabolic process 1.065362e-5
GO:0008207 C21-steroid hormone metabolic process 1.081558e-5
GO:0006982 response to lipid hydroperoxide 1.134896e-5
GO:0002238 response to molecule of fungal origin 1.193287e-5
GO:0002544 chronic inflammatory response 1.203515e-5
GO:0042325 regulation of phosphorylation 1.256049e-5
GO:0043068 positive regulation of programmed cell death 1.301136e-5
GO:0030856 regulation of epithelial cell differentiation 1.344079e-5
GO:0009893 positive regulation of metabolic process 1.370627e-5
GO:0044419 interspecies interaction between organisms 1.375580e-5
GO:0048489 synaptic vesicle transport 1.451715e-5
GO:0019220 regulation of phosphate metabolic process 1.518327e-5
GO:0021527 spinal cord association neuron differentiation 1.521237e-5
GO:0050900 leukocyte migration 1.525131e-5
GO:0034369 plasma lipoprotein particle remodeling 1.534519e-5
GO:0034765 regulation of ion transmembrane transport 1.537205e-5
GO:0014829 vascular smooth muscle contraction 1.537944e-5
GO:0019725 cellular homeostasis 1.599017e-5
GO:0032869 cellular response to insulin stimulus 1.607566e-5
GO:0048641 regulation of skeletal muscle tissue development 1.624588e-5
GO:0019229 regulation of vasoconstriction 1.662780e-5
GO:0071844 cellular component assembly at cellular level 1.670844e-5
GO:0010646 regulation of cell communication 1.681448e-5
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1.693471e-5
GO:0031399 regulation of protein modification process 1.748434e-5
GO:0030168 platelet activation 1.819743e-5
GO:0006631 fatty acid metabolic process 1.904995e-5
GO:0006725 cellular aromatic compound metabolic process 1.965825e-5
GO:0002687 positive regulation of leukocyte migration 2.000032e-5
GO:0070542 response to fatty acid 2.005862e-5
GO:0071345 cellular response to cytokine stimulus 2.060986e-5
GO:0007021 tubulin complex assembly 2.085117e-5
GO:0010744 positive regulation of macrophage derived foam cell differentiation 2.125532e-5
GO:0048520 positive regulation of behavior 2.206390e-5
GO:0006066 alcohol metabolic process 2.238103e-5
GO:0051412 response to corticosterone stimulus 2.285771e-5
GO:0007167 enzyme linked receptor protein signaling pathway 2.295178e-5
GO:0034383 low-density lipoprotein particle clearance 2.324974e-5
GO:0007276 gamete generation 2.399154e-5
GO:0043434 response to peptide hormone stimulus 2.436533e-5
GO:0019953 sexual reproduction 2.441500e-5
GO:0006633 fatty acid biosynthetic process 2.453012e-5
GO:0001932 regulation of protein phosphorylation 2.483070e-5
GO:0051050 positive regulation of transport 2.524053e-5
GO:0009266 response to temperature stimulus 2.526315e-5
GO:0001775 cell activation 2.593327e-5
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 2.594585e-5
GO:0071843 cellular component biogenesis at cellular level 2.597001e-5
GO:0030336 negative regulation of cell migration 2.606697e-5
GO:0046689 response to mercury ion 2.625557e-5
GO:0001906 cell killing 2.646643e-5
GO:0001692 histamine metabolic process 2.687175e-5
GO:0043652 engulfment of apoptotic cell 2.699447e-5
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.699447e-5
GO:0010754 negative regulation of cGMP-mediated signaling 2.699447e-5
GO:0010751 negative regulation of nitric oxide mediated signal transduction 2.699447e-5
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 2.699447e-5
GO:0090287 regulation of cellular response to growth factor stimulus 2.764350e-5
GO:0043065 positive regulation of apoptosis 2.815652e-5
GO:0051046 regulation of secretion 2.817600e-5
GO:0061008 hepaticobiliary system development 2.838894e-5
GO:0070101 positive regulation of chemokine-mediated signaling pathway 2.850405e-5
GO:0071347 cellular response to interleukin-1 2.956682e-5
GO:0042592 homeostatic process 2.964845e-5
GO:0031057 negative regulation of histone modification 3.095416e-5
GO:0032402 melanosome transport 3.181598e-5
GO:0033327 Leydig cell differentiation 3.236529e-5
GO:0018200 peptidyl-glutamic acid modification 3.250193e-5
GO:0002040 sprouting angiogenesis 3.289213e-5
GO:0048864 stem cell development 3.318590e-5
GO:0045575 basophil activation 3.329209e-5
GO:0001694 histamine biosynthetic process 3.329209e-5
GO:0022406 membrane docking 3.399404e-5
GO:0061041 regulation of wound healing 3.417037e-5
GO:0071599 otic vesicle development 3.493802e-5
GO:0034379 very-low-density lipoprotein particle assembly 3.503780e-5
GO:0007264 small GTPase mediated signal transduction 3.559309e-5
GO:0042108 positive regulation of cytokine biosynthetic process 3.563598e-5
GO:0030194 positive regulation of blood coagulation 3.630575e-5
GO:0048610 cellular process involved in reproduction 3.634742e-5
GO:0051240 positive regulation of multicellular organismal process 3.653609e-5
GO:0008285 negative regulation of cell proliferation 3.718119e-5
GO:0010466 negative regulation of peptidase activity 3.731621e-5
GO:0006212 uracil catabolic process 3.763645e-5
GO:0006210 thymine catabolic process 3.763645e-5
GO:0006813 potassium ion transport 3.783731e-5
GO:0003015 heart process 3.790652e-5
GO:0042632 cholesterol homeostasis 3.828753e-5
GO:0006897 endocytosis 3.982022e-5
GO:0048592 eye morphogenesis 4.262492e-5
GO:0001542 ovulation from ovarian follicle 4.279837e-5
GO:0030155 regulation of cell adhesion 4.289583e-5
GO:0043409 negative regulation of MAPKKK cascade 4.342111e-5
GO:0032319 regulation of Rho GTPase activity 4.615052e-5
GO:0042445 hormone metabolic process 4.631584e-5
GO:0006687 glycosphingolipid metabolic process 4.860315e-5
GO:0045764 positive regulation of cellular amino acid metabolic process 4.903910e-5
GO:0006887 exocytosis 4.945260e-5
GO:0045087 innate immune response 5.058659e-5
GO:0006091 generation of precursor metabolites and energy 5.098701e-5
GO:0019695 choline metabolic process 5.213361e-5
GO:0043653 mitochondrial fragmentation involved in apoptosis 5.315516e-5
GO:0045923 positive regulation of fatty acid metabolic process 5.481973e-5
GO:0034605 cellular response to heat 5.681234e-5
GO:0006144 purine base metabolic process 5.748673e-5
GO:0006638 neutral lipid metabolic process 5.786261e-5
GO:0040013 negative regulation of locomotion 5.820342e-5
GO:0046578 regulation of Ras protein signal transduction 5.907075e-5
GO:0050921 positive regulation of chemotaxis 5.925195e-5
GO:0032321 positive regulation of Rho GTPase activity 5.984217e-5
GO:0002688 regulation of leukocyte chemotaxis 6.153754e-5
GO:0006110 regulation of glycolysis 6.335869e-5
GO:0009120 deoxyribonucleoside metabolic process 6.403885e-5
GO:0034377 plasma lipoprotein particle assembly 6.405139e-5
GO:0032908 regulation of transforming growth factor beta1 production 6.565264e-5
GO:0046545 development of primary female sexual characteristics 6.744750e-5
GO:0009408 response to heat 6.806964e-5
GO:0051291 protein heterooligomerization 6.808773e-5
GO:0055085 transmembrane transport 7.011107e-5
GO:0051641 cellular localization 7.313487e-5
GO:0042035 regulation of cytokine biosynthetic process 7.352557e-5
GO:0022613 ribonucleoprotein complex biogenesis 7.434760e-5
GO:0006641 triglyceride metabolic process 7.442598e-5
GO:0034059 response to anoxia 7.582917e-5
GO:0001889 liver development 7.693318e-5
GO:0015718 monocarboxylic acid transport 7.807316e-5
GO:0006435 threonyl-tRNA aminoacylation 7.826277e-5
GO:0032400 melanosome localization 7.848807e-5
GO:0010632 regulation of epithelial cell migration 7.943858e-5
GO:0033552 response to vitamin B3 8.052951e-5
GO:0034220 ion transmembrane transport 8.059991e-5
GO:2000611 positive regulation of thyroid hormone generation 8.177776e-5
GO:0042554 superoxide anion generation 8.299297e-5
GO:0034284 response to monosaccharide stimulus 8.353436e-5
GO:0006497 protein lipidation 8.410768e-5
GO:0040011 locomotion 8.656967e-5
GO:0042159 lipoprotein catabolic process 8.733166e-5
GO:0031400 negative regulation of protein modification process 8.869344e-5
GO:0032401 establishment of melanosome localization 8.903013e-5
GO:0015705 iodide transport 8.903835e-5
GO:0006997 nucleus organization 9.138274e-5
GO:0046394 carboxylic acid biosynthetic process 9.352284e-5
GO:0071356 cellular response to tumor necrosis factor 9.383437e-5
GO:0070098 chemokine-mediated signaling pathway 9.549990e-5
GO:0034382 chylomicron remnant clearance 9.624418e-5
GO:0048741 skeletal muscle fiber development 9.682326e-5
GO:0030317 sperm motility 1.048566e-4
GO:0016202 regulation of striated muscle tissue development 1.053510e-4
GO:0008152 metabolic process 1.058604e-4
GO:0031099 regeneration 1.080766e-4
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 1.102339e-4
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1.109849e-4
GO:0006968 cellular defense response 1.118874e-4
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.119486e-4
GO:0008610 lipid biosynthetic process 1.122896e-4
GO:0042953 lipoprotein transport 1.124137e-4
GO:0010757 negative regulation of plasminogen activation 1.127860e-4
GO:0048145 regulation of fibroblast proliferation 1.137885e-4
GO:0045358 negative regulation of interferon-beta biosynthetic process 1.142002e-4
GO:0051346 negative regulation of hydrolase activity 1.144080e-4
GO:0042327 positive regulation of phosphorylation 1.168963e-4
GO:0006814 sodium ion transport 1.174143e-4
GO:0030031 cell projection assembly 1.188877e-4
GO:0045666 positive regulation of neuron differentiation 1.189503e-4
GO:0048246 macrophage chemotaxis 1.189942e-4
GO:0048087 positive regulation of developmental pigmentation 1.189942e-4
GO:0051904 pigment granule transport 1.205351e-4
GO:0048853 forebrain morphogenesis 1.237358e-4
GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity 1.241897e-4
GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway 1.241897e-4
GO:0034694 response to prostaglandin stimulus 1.244407e-4
GO:0097006 regulation of plasma lipoprotein particle levels 1.252468e-4
GO:0031325 positive regulation of cellular metabolic process 1.254194e-4
GO:0010886 positive regulation of cholesterol storage 1.261045e-4
GO:0006418 tRNA aminoacylation for protein translation 1.262394e-4
GO:0051651 maintenance of location in cell 1.271127e-4
GO:0010517 regulation of phospholipase activity 1.286080e-4
GO:0051657 maintenance of organelle location 1.301535e-4
GO:0006711 estrogen catabolic process 1.306937e-4
GO:0033240 positive regulation of cellular amine metabolic process 1.316378e-4
GO:0006939 smooth muscle contraction 1.348884e-4
GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger 1.355796e-4
GO:2000210 positive regulation of anoikis 1.368303e-4
GO:0071827 plasma lipoprotein particle organization 1.390756e-4
GO:0001921 positive regulation of receptor recycling 1.399563e-4
GO:0044238 primary metabolic process 1.433656e-4
GO:0046320 regulation of fatty acid oxidation 1.449177e-4
GO:0051480 cytosolic calcium ion homeostasis 1.468885e-4
GO:0051289 protein homotetramerization 1.477029e-4
GO:0007204 elevation of cytosolic calcium ion concentration 1.517962e-4
GO:0006412 translation 1.528781e-4
GO:0043252 sodium-independent organic anion transport 1.550186e-4
GO:0071456 cellular response to hypoxia 1.553198e-4
GO:0048147 negative regulation of fibroblast proliferation 1.589641e-4


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0050896 response to stimulus 6.333260e-15
GO:0006952 defense response 2.649732e-14
GO:0044255 cellular lipid metabolic process 7.876438e-12
GO:0006950 response to stress 1.746616e-11
GO:0006629 lipid metabolic process 1.880055e-11
GO:0032787 monocarboxylic acid metabolic process 8.815720e-11
GO:0032501 multicellular organismal process 9.307678e-11
GO:0006941 striated muscle contraction 1.126606e-10
GO:0051707 response to other organism 9.344821e-10
GO:0008610 lipid biosynthetic process 1.283253e-9
GO:0001887 selenium compound metabolic process 2.554091e-9
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 3.298328e-9
GO:0006082 organic acid metabolic process 4.557633e-9
GO:0009607 response to biotic stimulus 6.297443e-9
GO:0065008 regulation of biological quality 7.205502e-9
GO:0009617 response to bacterium 1.201312e-8
GO:0002684 positive regulation of immune system process 1.301181e-8
GO:0050865 regulation of cell activation 2.482438e-8
GO:0006936 muscle contraction 2.837369e-8
GO:0042180 cellular ketone metabolic process 3.203842e-8
GO:0019752 carboxylic acid metabolic process 3.434941e-8
GO:0002455 humoral immune response mediated by circulating immunoglobulin 3.602301e-8
GO:0002682 regulation of immune system process 4.206501e-8
GO:0051179 localization 5.036474e-8
GO:0002694 regulation of leukocyte activation 5.166456e-8
GO:0009611 response to wounding 5.806518e-8
GO:0006958 complement activation, classical pathway 8.198317e-8
GO:0002253 activation of immune response 8.946985e-8
GO:0006956 complement activation 9.725562e-8
GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 1.280367e-7
GO:0006631 fatty acid metabolic process 1.294272e-7
GO:0006633 fatty acid biosynthetic process 1.304485e-7
GO:0050953 sensory perception of light stimulus 1.589750e-7
GO:0044130 negative regulation of growth of symbiont in host 1.630832e-7
GO:0007601 visual perception 1.651398e-7
GO:0048304 positive regulation of isotype switching to IgG isotypes 1.785735e-7
GO:0019835 cytolysis 2.180790e-7
GO:0042221 response to chemical stimulus 2.334493e-7
GO:0050776 regulation of immune response 2.443822e-7
GO:0032101 regulation of response to external stimulus 2.754138e-7
GO:0072376 protein activation cascade 2.777720e-7
GO:0042742 defense response to bacterium 2.965519e-7
GO:0048302 regulation of isotype switching to IgG isotypes 3.139834e-7
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 3.216960e-7
GO:0043462 regulation of ATPase activity 4.640760e-7
GO:0007166 cell surface receptor linked signaling pathway 5.171171e-7
GO:0003008 system process 5.310166e-7
GO:0032094 response to food 5.839998e-7
GO:0019370 leukotriene biosynthetic process 6.565011e-7
GO:0050855 regulation of B cell receptor signaling pathway 7.413132e-7
GO:0051234 establishment of localization 7.441225e-7
GO:0001915 negative regulation of T cell mediated cytotoxicity 9.342441e-7
GO:0045619 regulation of lymphocyte differentiation 1.034285e-6
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 1.047356e-6
GO:0046456 icosanoid biosynthetic process 1.064143e-6
GO:0050870 positive regulation of T cell activation 1.281677e-6
GO:0050930 induction of positive chemotaxis 1.403572e-6
GO:0048807 female genitalia morphogenesis 1.440823e-6
GO:0060572 morphogenesis of an epithelial bud 1.474584e-6
GO:0032074 negative regulation of nuclease activity 1.629844e-6
GO:0046394 carboxylic acid biosynthetic process 1.726063e-6
GO:0050727 regulation of inflammatory response 1.789549e-6
GO:0050867 positive regulation of cell activation 2.002320e-6
GO:0001960 negative regulation of cytokine-mediated signaling pathway 2.047311e-6
GO:0006810 transport 2.060264e-6
GO:0045653 negative regulation of megakaryocyte differentiation 2.111051e-6
GO:0033275 actin-myosin filament sliding 2.176939e-6
GO:0003012 muscle system process 2.203108e-6
GO:0006636 unsaturated fatty acid biosynthetic process 2.381962e-6
GO:0000238 zygotene 2.462216e-6
GO:0034113 heterotypic cell-cell adhesion 2.799523e-6
GO:0007155 cell adhesion 2.969686e-6
GO:0001959 regulation of cytokine-mediated signaling pathway 3.023538e-6
GO:0048519 negative regulation of biological process 3.148490e-6
GO:0016310 phosphorylation 3.235205e-6
GO:0045580 regulation of T cell differentiation 3.446597e-6
GO:0044281 small molecule metabolic process 3.489397e-6
GO:0010941 regulation of cell death 3.635881e-6
GO:0048583 regulation of response to stimulus 3.755914e-6
GO:0008057 eye pigment granule organization 4.436310e-6
GO:0040018 positive regulation of multicellular organism growth 4.526180e-6
GO:0002696 positive regulation of leukocyte activation 4.536600e-6
GO:0045747 positive regulation of Notch signaling pathway 4.588435e-6
GO:0006200 ATP catabolic process 5.057703e-6
GO:0008152 metabolic process 5.277546e-6
GO:0007026 negative regulation of microtubule depolymerization 5.319925e-6
GO:0022610 biological adhesion 5.388054e-6
GO:0002252 immune effector process 5.399446e-6
GO:0045940 positive regulation of steroid metabolic process 5.508860e-6
GO:0060759 regulation of response to cytokine stimulus 5.577250e-6
GO:0050863 regulation of T cell activation 5.662611e-6
GO:2000107 negative regulation of leukocyte apoptosis 5.759459e-6
GO:0044283 small molecule biosynthetic process 5.995548e-6
GO:0007159 leukocyte cell-cell adhesion 6.141329e-6
GO:0006954 inflammatory response 6.677107e-6
GO:0016042 lipid catabolic process 6.769180e-6
GO:0002710 negative regulation of T cell mediated immunity 6.995125e-6
GO:0031114 regulation of microtubule depolymerization 7.014018e-6
GO:0006468 protein phosphorylation 7.209419e-6
GO:0070252 actin-mediated cell contraction 7.483542e-6
GO:0050852 T cell receptor signaling pathway 7.678590e-6
GO:0002700 regulation of production of molecular mediator of immune response 8.192183e-6
GO:0010627 regulation of intracellular protein kinase cascade 8.954983e-6
GO:0006959 humoral immune response 9.273378e-6
GO:0050854 regulation of antigen receptor-mediated signaling pathway 9.339018e-6
GO:0016265 death 9.413301e-6
GO:0051249 regulation of lymphocyte activation 9.555421e-6
GO:0030888 regulation of B cell proliferation 9.838061e-6
GO:0050927 positive regulation of positive chemotaxis 9.929277e-6
GO:0043901 negative regulation of multi-organism process 9.993654e-6
GO:0000245 spliceosome assembly 1.045018e-5
GO:0008219 cell death 1.173333e-5
GO:0040014 regulation of multicellular organism growth 1.198186e-5
GO:0043383 negative T cell selection 1.216178e-5
GO:0030540 female genitalia development 1.222213e-5
GO:0050790 regulation of catalytic activity 1.227897e-5
GO:0006928 cellular component movement 1.232386e-5
GO:0051241 negative regulation of multicellular organismal process 1.255159e-5
GO:0009410 response to xenobiotic stimulus 1.354372e-5
GO:0043067 regulation of programmed cell death 1.359238e-5
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 1.396446e-5
GO:0043086 negative regulation of catalytic activity 1.405201e-5
GO:0019098 reproductive behavior 1.434596e-5
GO:0070663 regulation of leukocyte proliferation 1.633733e-5
GO:0006691 leukotriene metabolic process 1.633866e-5
GO:0045582 positive regulation of T cell differentiation 1.663472e-5
GO:0002540 leukotriene production involved in inflammatory response 1.826351e-5
GO:0030049 muscle filament sliding 1.844712e-5
GO:0007275 multicellular organismal development 1.859402e-5
GO:0006435 threonyl-tRNA aminoacylation 1.876048e-5
GO:0023052 signaling 1.897645e-5
GO:0032944 regulation of mononuclear cell proliferation 1.928251e-5
GO:0051704 multi-organism process 1.936768e-5
GO:0002067 glandular epithelial cell differentiation 2.046392e-5
GO:0050670 regulation of lymphocyte proliferation 2.120350e-5
GO:0060594 mammary gland specification 2.131209e-5
GO:0007165 signal transduction 2.185728e-5
GO:0042102 positive regulation of T cell proliferation 2.207193e-5
GO:0051716 cellular response to stimulus 2.250667e-5
GO:0032946 positive regulation of mononuclear cell proliferation 2.273618e-5
GO:0016998 cell wall macromolecule catabolic process 2.409596e-5
GO:0070665 positive regulation of leukocyte proliferation 2.471561e-5
GO:0010817 regulation of hormone levels 2.512822e-5
GO:0042981 regulation of apoptosis 2.516446e-5
GO:0050671 positive regulation of lymphocyte proliferation 2.517732e-5
GO:0050926 regulation of positive chemotaxis 2.558093e-5
GO:0022612 gland morphogenesis 2.643352e-5
GO:0051251 positive regulation of lymphocyte activation 2.665176e-5
GO:0016337 cell-cell adhesion 2.688380e-5
GO:0032675 regulation of interleukin-6 production 2.701692e-5
GO:0006376 mRNA splice site selection 2.946113e-5
GO:0043542 endothelial cell migration 3.049123e-5
GO:2000974 negative regulation of pro-B cell differentiation 3.092790e-5
GO:0042628 mating plug formation 3.105801e-5
GO:0046635 positive regulation of alpha-beta T cell activation 3.183220e-5
GO:0090238 positive regulation of arachidonic acid secretion 3.223542e-5
GO:0043476 pigment accumulation 3.260118e-5
GO:0009956 radial pattern formation 3.260118e-5
GO:0050778 positive regulation of immune response 3.406006e-5
GO:0043242 negative regulation of protein complex disassembly 3.551777e-5
GO:0002820 negative regulation of adaptive immune response 3.572194e-5
GO:0021954 central nervous system neuron development 3.618378e-5
GO:0016477 cell migration 3.655928e-5
GO:0032502 developmental process 3.764553e-5
GO:0045658 regulation of neutrophil differentiation 3.772554e-5
GO:0019724 B cell mediated immunity 3.964632e-5
GO:0019853 L-ascorbic acid biosynthetic process 4.094138e-5
GO:0007219 Notch signaling pathway 4.107984e-5
GO:0007522 visceral muscle development 4.400745e-5
GO:0008593 regulation of Notch signaling pathway 4.487410e-5
GO:0046627 negative regulation of insulin receptor signaling pathway 4.602166e-5
GO:0032890 regulation of organic acid transport 4.760051e-5
GO:0042640 anagen 4.820969e-5
GO:0045060 negative thymic T cell selection 4.852295e-5
GO:0060197 cloacal septation 4.887347e-5
GO:0009605 response to external stimulus 4.913339e-5
GO:0006811 ion transport 5.122848e-5
GO:0016064 immunoglobulin mediated immune response 5.496533e-5
GO:0045926 negative regulation of growth 5.602382e-5
GO:0015669 gas transport 5.631000e-5
GO:0019538 protein metabolic process 5.815322e-5
GO:0010447 response to acidity 5.869777e-5
GO:0046034 ATP metabolic process 5.941057e-5
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.108518e-5
GO:0032652 regulation of interleukin-1 production 6.227666e-5
GO:0006796 phosphate-containing compound metabolic process 6.257354e-5
GO:0090270 regulation of fibroblast growth factor production 6.578257e-5
GO:0007499 ectoderm and mesoderm interaction 6.578257e-5
GO:0035385 Roundabout signaling pathway 6.708092e-5
GO:0050707 regulation of cytokine secretion 6.983033e-5
GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development 8.174457e-5
GO:0050821 protein stabilization 8.569104e-5
GO:0050925 negative regulation of negative chemotaxis 8.678935e-5
GO:0006955 immune response 8.728207e-5
GO:0021539 subthalamus development 8.826249e-5
GO:0046634 regulation of alpha-beta T cell activation 8.997703e-5
GO:0007154 cell communication 9.291012e-5
GO:0010939 regulation of necrotic cell death 9.401226e-5
GO:0030168 platelet activation 9.445499e-5
GO:0045087 innate immune response 9.817569e-5
GO:0045588 positive regulation of gamma-delta T cell differentiation 1.010413e-4
GO:0010942 positive regulation of cell death 1.040411e-4
GO:0045191 regulation of isotype switching 1.046482e-4
GO:0045621 positive regulation of lymphocyte differentiation 1.048732e-4
GO:0002922 positive regulation of humoral immune response 1.051453e-4
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 1.113827e-4
GO:0007517 muscle organ development 1.127406e-4
GO:0019637 organophosphate metabolic process 1.142050e-4
GO:0060048 cardiac muscle contraction 1.150795e-4
GO:0042060 wound healing 1.155741e-4
GO:0007010 cytoskeleton organization 1.169757e-4
GO:0006644 phospholipid metabolic process 1.193854e-4
GO:0051024 positive regulation of immunoglobulin secretion 1.225056e-4
GO:0032651 regulation of interleukin-1 beta production 1.283257e-4
GO:0060537 muscle tissue development 1.299453e-4
GO:0008207 C21-steroid hormone metabolic process 1.305788e-4
GO:0040008 regulation of growth 1.318194e-4
GO:0035025 positive regulation of Rho protein signal transduction 1.427190e-4
GO:0051240 positive regulation of multicellular organismal process 1.432366e-4
GO:0044238 primary metabolic process 1.444327e-4
GO:0002637 regulation of immunoglobulin production 1.450233e-4
GO:0046641 positive regulation of alpha-beta T cell proliferation 1.470109e-4
GO:0009056 catabolic process 1.482239e-4
GO:0032103 positive regulation of response to external stimulus 1.534620e-4
GO:0031620 regulation of fever generation 1.541163e-4
GO:0031111 negative regulation of microtubule polymerization or depolymerization 1.592945e-4
GO:0007512 adult heart development 1.602264e-4
GO:0050901 leukocyte tethering or rolling 1.622322e-4
GO:0045665 negative regulation of neuron differentiation 1.655147e-4
GO:0033628 regulation of cell adhesion mediated by integrin 1.676522e-4
GO:0046626 regulation of insulin receptor signaling pathway 1.704600e-4
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1.711831e-4
GO:0051023 regulation of immunoglobulin secretion 1.736285e-4
GO:0046877 regulation of saliva secretion 1.745039e-4
GO:0060571 morphogenesis of an epithelial fold 1.752736e-4
GO:0043244 regulation of protein complex disassembly 1.795963e-4
GO:0006805 xenobiotic metabolic process 1.819298e-4
GO:0060443 mammary gland morphogenesis 1.839703e-4
GO:0070229 negative regulation of lymphocyte apoptosis 1.844241e-4
GO:0022410 circadian sleep/wake cycle process 1.865951e-4
GO:0021953 central nervous system neuron differentiation 1.869686e-4
GO:0051282 regulation of sequestering of calcium ion 1.873964e-4
GO:0048856 anatomical structure development 1.897392e-4
GO:0051043 regulation of membrane protein ectodomain proteolysis 1.908243e-4
GO:0002065 columnar/cuboidal epithelial cell differentiation 1.922719e-4
GO:0060992 response to fungicide 1.990073e-4
GO:0007596 blood coagulation 1.998835e-4
GO:0002275 myeloid cell activation involved in immune response 2.002081e-4
GO:0042745 circadian sleep/wake cycle 2.210794e-4
GO:0034375 high-density lipoprotein particle remodeling 2.319264e-4
GO:0002026 regulation of the force of heart contraction 2.339090e-4
GO:0002528 regulation of vascular permeability involved in acute inflammatory response 2.348488e-4
GO:0070368 positive regulation of hepatocyte differentiation 2.396989e-4
GO:0002237 response to molecule of bacterial origin 2.422707e-4
GO:0007186 G-protein coupled receptor protein signaling pathway 2.431692e-4
GO:0050864 regulation of B cell activation 2.438086e-4
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 2.450444e-4
GO:0048523 negative regulation of cellular process 2.473124e-4
GO:0007033 vacuole organization 2.474035e-4
GO:0043068 positive regulation of programmed cell death 2.485796e-4
GO:0031329 regulation of cellular catabolic process 2.535185e-4
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine 2.555310e-4
GO:0032844 regulation of homeostatic process 2.568820e-4
GO:0000187 activation of MAPK activity 2.583338e-4
GO:0045830 positive regulation of isotype switching 2.596601e-4
GO:0002740 negative regulation of cytokine secretion involved in immune response 2.642948e-4
GO:0042445 hormone metabolic process 2.676615e-4
GO:2000193 positive regulation of fatty acid transport 2.737455e-4
GO:0060047 heart contraction 2.738221e-4
GO:0009636 response to toxin 2.823840e-4
GO:0007599 hemostasis 2.845313e-4
GO:0061077 chaperone-mediated protein folding 2.877692e-4
GO:0043065 positive regulation of apoptosis 2.883581e-4
GO:0046164 alcohol catabolic process 2.884438e-4
GO:0008202 steroid metabolic process 2.966432e-4
GO:0006690 icosanoid metabolic process 3.002017e-4
GO:0007172 signal complex assembly 3.036295e-4
GO:0045834 positive regulation of lipid metabolic process 3.043338e-4
GO:0060661 submandibular salivary gland formation 3.049231e-4
GO:0061115 lung proximal/distal axis specification 3.049231e-4
GO:0070352 positive regulation of white fat cell proliferation 3.049231e-4
GO:0070075 tear secretion 3.049231e-4
GO:0060879 semicircular canal fusion 3.049231e-4
GO:0060496 mesenchymal-epithelial cell signaling involved in lung development 3.049231e-4
GO:0050677 positive regulation of urothelial cell proliferation 3.049231e-4
GO:0050674 urothelial cell proliferation 3.049231e-4
GO:0060436 bronchiole morphogenesis 3.049231e-4
GO:0002376 immune system process 3.191171e-4
GO:0048869 cellular developmental process 3.231704e-4
GO:0002739 regulation of cytokine secretion involved in immune response 3.273905e-4
GO:0050877 neurological system process 3.416145e-4
GO:0055114 oxidation-reduction process 3.478633e-4
GO:0051964 negative regulation of synapse assembly 3.494359e-4
GO:0019511 peptidyl-proline hydroxylation 3.494359e-4
GO:0007217 tachykinin receptor signaling pathway 3.494359e-4
GO:0033690 positive regulation of osteoblast proliferation 3.569965e-4
GO:0060648 mammary gland bud morphogenesis 3.606950e-4
GO:0070527 platelet aggregation 3.616535e-4
GO:0070366 regulation of hepatocyte differentiation 3.616535e-4
GO:0006457 protein folding 3.776834e-4
GO:0032496 response to lipopolysaccharide 3.840217e-4
GO:0060548 negative regulation of cell death 3.881604e-4
GO:0044242 cellular lipid catabolic process 3.902172e-4
GO:0008015 blood circulation 3.981341e-4
GO:0051977 lysophospholipid transport 4.008803e-4
GO:0001942 hair follicle development 4.036528e-4
GO:0080134 regulation of response to stress 4.096370e-4
GO:0006957 complement activation, alternative pathway 4.206558e-4
GO:0006915 apoptosis 4.255406e-4
GO:0006167 AMP biosynthetic process 4.301830e-4
GO:0016198 axon choice point recognition 4.306515e-4
GO:0046640 regulation of alpha-beta T cell proliferation 4.339773e-4
GO:0003229 ventricular cardiac muscle tissue development 4.376452e-4
GO:0060915 mesenchymal cell differentiation involved in lung development 4.399316e-4
GO:0060667 branch elongation involved in salivary gland morphogenesis 4.399316e-4
GO:0060615 mammary gland bud formation 4.399316e-4
GO:0060595 fibroblast growth factor receptor signaling pathway involved in mammary gland specification 4.399316e-4
GO:0046341 CDP-diacylglycerol metabolic process 4.454950e-4
GO:0030154 cell differentiation 4.462538e-4
GO:0048589 developmental growth 4.481131e-4
GO:0014807 regulation of somitogenesis 4.557162e-4
GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 4.557162e-4
GO:0032463 negative regulation of protein homooligomerization 4.610331e-4
GO:0030889 negative regulation of B cell proliferation 4.623664e-4
GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine 4.641356e-4
GO:0042135 neurotransmitter catabolic process 4.656647e-4
GO:0007268 synaptic transmission 4.661948e-4
GO:0006816 calcium ion transport 4.702186e-4
GO:0050878 regulation of body fluid levels 4.913550e-4
GO:0014706 striated muscle tissue development 4.920496e-4
GO:0048513 organ development 4.981483e-4
GO:0031657 regulation of cyclin-dependent protein kinase activity involved in G1/S 4.990507e-4
GO:0032892 positive regulation of organic acid transport 5.056248e-4
GO:0006953 acute-phase response 5.163628e-4
GO:0051952 regulation of amine transport 5.188558e-4
GO:0006436 tryptophanyl-tRNA aminoacylation 5.225389e-4
GO:0050704 regulation of interleukin-1 secretion 5.331901e-4
GO:0009888 tissue development 5.504988e-4
GO:0042404 thyroid hormone catabolic process 5.581409e-4
GO:0045577 regulation of B cell differentiation 5.625830e-4
GO:0009894 regulation of catabolic process 5.626615e-4
GO:0071287 cellular response to manganese ion 5.678570e-4
GO:0051961 negative regulation of nervous system development 5.678570e-4
GO:0051338 regulation of transferase activity 5.704498e-4
GO:0001738 morphogenesis of a polarized epithelium 5.764645e-4
GO:0002642 positive regulation of immunoglobulin biosynthetic process 5.831106e-4
GO:0055065 metal ion homeostasis 5.833331e-4
GO:0002443 leukocyte mediated immunity 5.843543e-4
GO:0042364 water-soluble vitamin biosynthetic process 5.860427e-4
GO:0042633 hair cycle 5.874663e-4
GO:0032755 positive regulation of interleukin-6 production 5.990550e-4
GO:0012501 programmed cell death 6.032350e-4
GO:0045357 regulation of interferon-beta biosynthetic process 6.032717e-4
GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S 6.077231e-4
GO:0042938 dipeptide transport 6.106667e-4
GO:0045061 thymic T cell selection 6.109822e-4
GO:0002526 acute inflammatory response 6.258393e-4
GO:0044057 regulation of system process 6.483048e-4
GO:0050706 regulation of interleukin-1 beta secretion 6.529923e-4
GO:0048870 cell motility 6.617781e-4
GO:0050709 negative regulation of protein secretion 6.627258e-4
GO:0051209 release of sequestered calcium ion into cytosol 6.638664e-4
GO:0035644 phosphoanandamide dephosphorylation 6.676685e-4
GO:0043069 negative regulation of programmed cell death 6.727349e-4
GO:0010893 positive regulation of steroid biosynthetic process 6.819816e-4
GO:0042129 regulation of T cell proliferation 6.863016e-4
GO:0044058 regulation of digestive system process 6.872983e-4
GO:0002281 macrophage activation involved in immune response 6.893392e-4
GO:0044092 negative regulation of molecular function 6.910901e-4
GO:2000466 negative regulation of glycogen (starch) synthase activity 7.010195e-4
GO:0042891 antibiotic transport 7.010195e-4
GO:0006925 inflammatory cell apoptosis 7.010195e-4
GO:0040011 locomotion 7.071213e-4
GO:0030859 polarized epithelial cell differentiation 7.158957e-4
GO:0070684 seminal clot liquefaction 7.213068e-4
GO:0051932 synaptic transmission, GABAergic 7.213068e-4
GO:0048747 muscle fiber development 7.213769e-4
GO:0032495 response to muramyl dipeptide 7.225824e-4
GO:0050869 negative regulation of B cell activation 7.234524e-4
GO:0031640 killing of cells of other organism 7.258492e-4
GO:0050830 defense response to Gram-positive bacterium 7.283401e-4
GO:0010033 response to organic substance 7.310380e-4
GO:0050684 regulation of mRNA processing 7.319944e-4
GO:0048518 positive regulation of biological process 7.335235e-4
GO:0007618 mating 7.358779e-4
GO:0007320 insemination 7.770109e-4
GO:0042104 positive regulation of activated T cell proliferation 8.083301e-4
GO:0002902 regulation of B cell apoptosis 8.140255e-4
GO:0000398 nuclear mRNA splicing, via spliceosome 8.145755e-4
GO:0060558 regulation of calcidiol 1-monooxygenase activity 8.157338e-4
GO:0009395 phospholipid catabolic process 8.171065e-4
GO:0003218 cardiac left ventricle formation 8.251453e-4
GO:0043066 negative regulation of apoptosis 8.317079e-4
GO:0060557 positive regulation of vitamin D biosynthetic process 8.478175e-4
GO:0070228 regulation of lymphocyte apoptosis 8.478675e-4
GO:0045187 regulation of circadian sleep/wake cycle, sleep 8.541206e-4
GO:0008624 induction of apoptosis by extracellular signals 8.695855e-4
GO:0042219 cellular modified amino acid catabolic process 8.838453e-4
GO:0032781 positive regulation of ATPase activity 8.941872e-4
GO:0042446 hormone biosynthetic process 9.119463e-4
GO:0050795 regulation of behavior 9.229619e-4
GO:0009615 response to virus 9.296633e-4
GO:0051659 maintenance of mitochondrion location 9.325521e-4
GO:0050729 positive regulation of inflammatory response 9.326125e-4
GO:0022038 corpus callosum development 9.386960e-4
GO:0000375 RNA splicing, via transesterification reactions 9.460732e-4
GO:0070307 lens fiber cell development 9.480313e-4
GO:0072233 metanephric thick ascending limb development 9.568324e-4
GO:0072218 metanephric ascending thin limb development 9.568324e-4
GO:0003013 circulatory system process 9.996149e-4
GO:0046579 positive regulation of Ras protein signal transduction 1.001112e-3
GO:0071840 cellular component organization or biogenesis 1.004591e-3
GO:0002757 immune response-activating signal transduction 1.014835e-3
GO:0051788 response to misfolded protein 1.018469e-3
GO:0015893 drug transport 1.022090e-3
GO:0042402 cellular biogenic amine catabolic process 1.023597e-3
GO:0048731 system development 1.024280e-3
GO:0070346 positive regulation of fat cell proliferation 1.030096e-3
GO:0046475 glycerophospholipid catabolic process 1.030096e-3
GO:0006597 spermine biosynthetic process 1.034904e-3
GO:0032078 negative regulation of endodeoxyribonuclease activity 1.034904e-3
GO:0051025 negative regulation of immunoglobulin secretion 1.034904e-3
GO:0006922 cleavage of lamin 1.034904e-3
GO:0060164 regulation of timing of neuron differentiation 1.035297e-3
GO:0051348 negative regulation of transferase activity 1.054595e-3
GO:0071773 cellular response to BMP stimulus 1.064342e-3
GO:0060690 epithelial cell differentiation involved in salivary gland development 1.067297e-3
GO:0048711 positive regulation of astrocyte differentiation 1.074931e-3
GO:0060592 mammary gland formation 1.082880e-3
GO:0002764 immune response-regulating signaling pathway 1.101108e-3
GO:0034384 high-density lipoprotein particle clearance 1.102673e-3
GO:0048584 positive regulation of response to stimulus 1.111127e-3
GO:0045616 regulation of keratinocyte differentiation 1.124860e-3
GO:0007600 sensory perception 1.128392e-3
GO:0046033 AMP metabolic process 1.128825e-3
GO:0018149 peptide cross-linking 1.150397e-3
GO:0031069 hair follicle morphogenesis 1.161288e-3
GO:0048692 negative regulation of axon extension involved in regeneration 1.164664e-3
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 1.164664e-3
GO:0018158 protein oxidation 1.164664e-3
GO:0000073 spindle pole body separation 1.164664e-3
GO:0022417 protein maturation by protein folding 1.164664e-3
GO:0032692 negative regulation of interleukin-1 production 1.168337e-3
GO:0055085 transmembrane transport 1.187823e-3
GO:0009653 anatomical structure morphogenesis 1.227331e-3
GO:0045911 positive regulation of DNA recombination 1.227893e-3
GO:0043508 negative regulation of JUN kinase activity 1.228875e-3
GO:0045124 regulation of bone resorption 1.234872e-3
GO:0033081 regulation of T cell differentiation in thymus 1.239533e-3
GO:0051883 killing of cells in other organism involved in symbiotic interaction 1.253328e-3
GO:0002903 negative regulation of B cell apoptosis 1.260614e-3
GO:0030890 positive regulation of B cell proliferation 1.301223e-3
GO:0072017 distal tubule development 1.324199e-3
GO:0001555 oocyte growth 1.327014e-3
GO:0007266 Rho protein signal transduction 1.328198e-3
GO:0031622 positive regulation of fever generation 1.335380e-3
GO:0019852 L-ascorbic acid metabolic process 1.338956e-3
GO:0040007 growth 1.339122e-3
GO:0000072 M phase specific microtubule process 1.343699e-3
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 1.361222e-3
GO:0008299 isoprenoid biosynthetic process 1.364016e-3
GO:0010872 regulation of cholesterol esterification 1.369413e-3
GO:0035588 G-protein coupled purinergic receptor signaling pathway 1.373276e-3
GO:0048541 Peyer's patch development 1.387057e-3
GO:0060513 prostatic bud formation 1.409523e-3
GO:0070493 thrombin receptor signaling pathway 1.436997e-3
GO:0060555 induction of necroptosis by extracellular signals 1.436997e-3
GO:0003171 atrioventricular valve development 1.437357e-3
GO:0032691 negative regulation of interleukin-1 beta production 1.440478e-3
GO:0014823 response to activity 1.456314e-3
GO:0071875 adrenergic receptor signaling pathway 1.464172e-3
GO:0050881 musculoskeletal movement 1.482702e-3
GO:0010873 positive regulation of cholesterol esterification 1.497877e-3
GO:2000191 regulation of fatty acid transport 1.512546e-3
GO:0001937 negative regulation of endothelial cell proliferation 1.520049e-3
GO:0051341 regulation of oxidoreductase activity 1.529712e-3
GO:0055080 cation homeostasis 1.546362e-3
GO:0006812 cation transport 1.589688e-3
GO:0051657 maintenance of organelle location 1.599746e-3
GO:0034638 phosphatidylcholine catabolic process 1.619648e-3
GO:0034754 cellular hormone metabolic process 1.625940e-3
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 1.642343e-3
GO:0034109 homotypic cell-cell adhesion 1.651619e-3
GO:0048630 skeletal muscle tissue growth 1.689765e-3
GO:0030644 cellular chloride ion homeostasis 1.689765e-3
GO:0009110 vitamin biosynthetic process 1.694086e-3
GO:0033674 positive regulation of kinase activity 1.694199e-3
GO:0051494 negative regulation of cytoskeleton organization 1.712574e-3
GO:0016199 axon midline choice point recognition 1.715682e-3
GO:0050920 regulation of chemotaxis 1.728939e-3
GO:0045664 regulation of neuron differentiation 1.745564e-3
GO:0006581 acetylcholine catabolic process 1.749440e-3
GO:0007417 central nervous system development 1.780178e-3
GO:0034103 regulation of tissue remodeling 1.806160e-3
GO:0008306 associative learning 1.807734e-3
GO:0002649 regulation of tolerance induction to self antigen 1.813228e-3
GO:0030048 actin filament-based movement 1.815866e-3
GO:0050433 regulation of catecholamine secretion 1.836198e-3
GO:0033622 integrin activation 1.851863e-3
GO:0045358 negative regulation of interferon-beta biosynthetic process 1.851863e-3