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Novel motif:58

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name:motif58_CGGNAT

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:2000465 regulation of glycogen (starch) synthase activity 2.560208e-10
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 2.533555e-9
GO:0006414 translational elongation 4.321773e-9
GO:0016032 viral reproduction 6.308620e-9
GO:0006369 termination of RNA polymerase II transcription 1.487240e-8
GO:0046628 positive regulation of insulin receptor signaling pathway 1.728920e-8
GO:0014057 positive regulation of acetylcholine secretion 4.714360e-8
GO:0048143 astrocyte activation 4.979486e-8
GO:0050434 positive regulation of viral transcription 8.132806e-8
GO:0006353 transcription termination, DNA-dependent 1.439171e-7
GO:0046782 regulation of viral transcription 1.723801e-7
GO:0006415 translational termination 1.849412e-7
GO:0032790 ribosome disassembly 2.220130e-7
GO:2000378 negative regulation of reactive oxygen species metabolic process 2.367296e-7
GO:0019083 viral transcription 5.402517e-7
GO:0044258 intestinal lipid catabolic process 7.775215e-7
GO:0018350 protein esterification 7.775215e-7
GO:2000467 positive regulation of glycogen (starch) synthase activity 7.823945e-7
GO:0015820 leucine transport 8.526112e-7
GO:0035356 cellular triglyceride homeostasis 1.008223e-6
GO:0014056 regulation of acetylcholine secretion 1.757019e-6
GO:0006283 transcription-coupled nucleotide-excision repair 1.865622e-6
GO:0006370 mRNA capping 3.088575e-6
GO:0009452 RNA capping 3.208213e-6
GO:0008033 tRNA processing 3.809284e-6
GO:0006102 isocitrate metabolic process 4.154322e-6
GO:0046626 regulation of insulin receptor signaling pathway 5.174270e-6
GO:0031017 exocrine pancreas development 5.386896e-6
GO:0007140 male meiosis 5.693234e-6
GO:0045725 positive regulation of glycogen biosynthetic process 5.839122e-6
GO:0006289 nucleotide-excision repair 6.038255e-6
GO:2000466 negative regulation of glycogen (starch) synthase activity 7.081697e-6
GO:0009650 UV protection 7.478181e-6
GO:0010626 negative regulation of Schwann cell proliferation 8.639595e-6
GO:0021591 ventricular system development 1.070165e-5
GO:0034633 retinol transport 1.295361e-5
GO:0030853 negative regulation of granulocyte differentiation 1.565864e-5
GO:0031064 negative regulation of histone deacetylation 1.658980e-5
GO:0046521 sphingoid catabolic process 1.691197e-5
GO:0051534 negative regulation of NFAT protein import into nucleus 1.730921e-5
GO:0048524 positive regulation of viral reproduction 1.784349e-5
GO:0006412 translation 1.821585e-5
GO:0048102 autophagic cell death 2.089188e-5
GO:0006368 transcription elongation from RNA polymerase II promoter 2.273361e-5
GO:0008588 release of cytoplasmic sequestered NF-kappaB 2.577305e-5
GO:0007141 male meiosis I 2.758859e-5
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 2.835060e-5
GO:0034623 cellular macromolecular complex disassembly 2.901680e-5
GO:0032984 macromolecular complex disassembly 2.997680e-5
GO:0031643 positive regulation of myelination 3.106154e-5
GO:0030823 regulation of cGMP metabolic process 3.192155e-5
GO:0016071 mRNA metabolic process 3.518600e-5
GO:0042946 glucoside transport 4.516616e-5
GO:0006396 RNA processing 4.965297e-5
GO:0030825 positive regulation of cGMP metabolic process 5.061599e-5
GO:0043624 cellular protein complex disassembly 5.173111e-5
GO:0010509 polyamine homeostasis 5.258169e-5
GO:0043241 protein complex disassembly 5.454029e-5
GO:0040040 thermosensory behavior 5.891931e-5
GO:0006103 2-oxoglutarate metabolic process 6.325516e-5
GO:0034619 cellular chaperone-mediated protein complex assembly 6.496088e-5
GO:0021670 lateral ventricle development 6.547530e-5
GO:0000389 nuclear mRNA 3'-splice site recognition 6.576428e-5
GO:0070875 positive regulation of glycogen metabolic process 6.649022e-5
GO:0003417 growth plate cartilage development 7.047730e-5
GO:0006366 transcription from RNA polymerase II promoter 7.161073e-5
GO:0061360 optic chiasma development 7.634015e-5
GO:2000597 positive regulation of optic nerve formation 7.634015e-5
GO:0021650 vestibulocochlear nerve formation 7.634015e-5
GO:0021633 optic nerve structural organization 7.634015e-5
GO:0035799 ureter maturation 7.634015e-5
GO:0043486 histone exchange 7.638119e-5
GO:0046543 development of secondary female sexual characteristics 7.811716e-5
GO:0045136 development of secondary sexual characteristics 7.902127e-5
GO:0030237 female sex determination 7.922918e-5
GO:0035928 rRNA import into mitochondrion 8.299133e-5
GO:0003406 retinal pigment epithelium development 9.124586e-5
GO:0009062 fatty acid catabolic process 9.831125e-5
GO:0002072 optic cup morphogenesis involved in camera-type eye development 1.002544e-4
GO:0030213 hyaluronan biosynthetic process 1.020481e-4
GO:0033083 regulation of immature T cell proliferation 1.076975e-4
GO:0000080 G1 phase of mitotic cell cycle 1.184465e-4
GO:0019058 viral infectious cycle 1.240095e-4
GO:0021603 cranial nerve formation 1.256598e-4
GO:0000731 DNA synthesis involved in DNA repair 1.256598e-4
GO:0046395 carboxylic acid catabolic process 1.296995e-4
GO:0046778 modification by virus of host mRNA processing 1.297344e-4
GO:0009440 cyanate catabolic process 1.297344e-4
GO:0034470 ncRNA processing 1.319266e-4
GO:0072329 monocarboxylic acid catabolic process 1.329088e-4
GO:0032312 regulation of ARF GTPase activity 1.390406e-4
GO:0043585 nose morphogenesis 1.468022e-4
GO:0060351 cartilage development involved in endochondral bone morphogenesis 1.469247e-4
GO:0030157 pancreatic juice secretion 1.479860e-4
GO:0000375 RNA splicing, via transesterification reactions 1.494113e-4
GO:0032863 activation of Rac GTPase activity 1.552920e-4
GO:0000398 nuclear mRNA splicing, via spliceosome 1.578610e-4
GO:0032230 positive regulation of synaptic transmission, GABAergic 1.586679e-4
GO:0070253 somatostatin secretion 1.591463e-4
GO:0032812 positive regulation of epinephrine secretion 1.591463e-4
GO:0018293 protein-FAD linkage 1.646623e-4
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 1.646623e-4
GO:0032988 ribonucleoprotein complex disassembly 1.658595e-4
GO:0006383 transcription from RNA polymerase III promoter 1.736067e-4
GO:0035815 positive regulation of renal sodium excretion 1.822288e-4
GO:0005979 regulation of glycogen biosynthetic process 1.826284e-4
GO:0034080 CenH3-containing nucleosome assembly at centromere 1.840030e-4
GO:0019303 D-ribose catabolic process 2.006826e-4
GO:0043171 peptide catabolic process 2.153480e-4
GO:0043044 ATP-dependent chromatin remodeling 2.155910e-4
GO:0060253 negative regulation of glial cell proliferation 2.170092e-4
GO:0031914 negative regulation of synaptic plasticity 2.218940e-4
GO:0061054 dermatome development 2.301068e-4
GO:0030178 negative regulation of Wnt receptor signaling pathway 2.301513e-4
GO:0007288 sperm axoneme assembly 2.347550e-4
GO:0031018 endocrine pancreas development 2.447462e-4
GO:0006458 'de novo' protein folding 2.476082e-4
GO:0050432 catecholamine secretion 2.594660e-4
GO:0060356 leucine import 2.732263e-4
GO:2000009 negative regulation of protein localization at cell surface 2.788525e-4
GO:0090031 positive regulation of steroid hormone biosynthetic process 2.957438e-4
GO:0009296 flagellum assembly 3.050274e-4
GO:0042762 regulation of sulfur metabolic process 3.062487e-4
GO:0003329 pancreatic PP cell fate commitment 3.074411e-4
GO:0003326 pancreatic A cell fate commitment 3.074411e-4
GO:0046514 ceramide catabolic process 3.094446e-4
GO:0000154 rRNA modification 3.159328e-4
GO:0034389 lipid particle organization 3.387175e-4
GO:0006930 substrate-dependent cell migration, cell extension 3.418246e-4
GO:0006398 histone mRNA 3'-end processing 3.597948e-4
GO:0051029 rRNA transport 3.712884e-4
GO:0034111 negative regulation of homotypic cell-cell adhesion 3.712884e-4
GO:0043381 negative regulation of memory T cell differentiation 3.773086e-4
GO:0043538 regulation of actin phosphorylation 3.773086e-4
GO:0006409 tRNA export from nucleus 3.895610e-4
GO:0010954 positive regulation of protein processing 4.163545e-4
GO:0035621 ER to Golgi ceramide transport 4.234481e-4
GO:0072553 terminal button organization 4.234481e-4
GO:0033084 regulation of immature T cell proliferation in thymus 4.244477e-4
GO:0051176 positive regulation of sulfur metabolic process 4.351064e-4
GO:0045040 protein import into mitochondrial outer membrane 4.440934e-4
GO:0032228 regulation of synaptic transmission, GABAergic 4.547167e-4
GO:0001886 endothelial cell morphogenesis 4.581503e-4
GO:0042797 tRNA transcription from RNA polymerase III promoter 4.978954e-4
GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter 4.978954e-4
GO:0035090 maintenance of apical/basal cell polarity 4.992308e-4
GO:0015853 adenine transport 5.310581e-4
GO:0006987 activation of signaling protein activity involved in unfolded protein response 5.391027e-4
GO:0045199 maintenance of epithelial cell apical/basal polarity 5.671407e-4
GO:0030208 dermatan sulfate biosynthetic process 5.671407e-4
GO:0006772 thiamine metabolic process 5.884144e-4
GO:0035411 catenin import into nucleus 6.115041e-4
GO:0032855 positive regulation of Rac GTPase activity 6.126914e-4
GO:0030852 regulation of granulocyte differentiation 6.162972e-4
GO:0090103 cochlea morphogenesis 6.289009e-4
GO:0061037 negative regulation of cartilage development 6.344606e-4
GO:0002679 respiratory burst involved in defense response 6.352834e-4
GO:0015886 heme transport 6.352834e-4
GO:2000119 negative regulation of sodium-dependent phosphate transport 6.404675e-4
GO:0014819 regulation of skeletal muscle contraction 6.515245e-4
GO:0007023 post-chaperonin tubulin folding pathway 6.515245e-4
GO:0072300 positive regulation of metanephric glomerulus development 6.702148e-4
GO:0071897 DNA biosynthetic process 6.825963e-4
GO:0031558 induction of apoptosis in response to chemical stimulus 6.871621e-4
GO:0006399 tRNA metabolic process 7.468683e-4
GO:0006635 fatty acid beta-oxidation 7.539795e-4
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 7.595230e-4
GO:0042254 ribosome biogenesis 7.706104e-4
GO:0006097 glyoxylate cycle 7.851461e-4
GO:0009301 snRNA transcription 7.930164e-4
GO:0021932 hindbrain radial glia guided cell migration 8.278973e-4
GO:0032674 regulation of interleukin-5 production 8.398535e-4
GO:0045655 regulation of monocyte differentiation 8.554140e-4
GO:0031055 chromatin remodeling at centromere 8.578218e-4
GO:0033260 DNA replication involved in S phase 8.630683e-4
GO:0042450 arginine biosynthetic process via ornithine 8.630683e-4
GO:0031118 rRNA pseudouridine synthesis 8.630683e-4
GO:0008049 male courtship behavior 8.630683e-4
GO:0010734 negative regulation of protein glutathionylation 8.630683e-4
GO:0021933 radial glia guided migration of cerebellar granule cell 8.630683e-4
GO:0001957 intramembranous ossification 8.834371e-4
GO:0021562 vestibulocochlear nerve development 8.882302e-4
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway 9.170239e-4
GO:0070873 regulation of glycogen metabolic process 9.424392e-4
GO:0021559 trigeminal nerve development 9.632101e-4
GO:0021526 medial motor column neuron differentiation 1.016294e-3
GO:0010756 positive regulation of plasminogen activation 1.062215e-3
GO:0043089 positive regulation of Cdc42 GTPase activity 1.076181e-3
GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein 1.083626e-3
GO:0001970 positive regulation of activation of membrane attack complex 1.091126e-3
GO:0009304 tRNA transcription 1.098588e-3
GO:0043491 protein kinase B signaling cascade 1.123290e-3
GO:0014044 Schwann cell development 1.154633e-3
GO:0051084 'de novo' posttranslational protein folding 1.157539e-3
GO:0002121 inter-male aggressive behavior 1.162987e-3
GO:0048069 eye pigmentation 1.165699e-3
GO:0014020 primary neural tube formation 1.173391e-3
GO:0006457 protein folding 1.174708e-3
GO:0043064 flagellum organization 1.183395e-3
GO:0034498 early endosome to Golgi transport 1.184524e-3
GO:0048313 Golgi inheritance 1.184524e-3
GO:0006612 protein targeting to membrane 1.184765e-3
GO:0032754 positive regulation of interleukin-5 production 1.243159e-3
GO:0002149 hypochlorous acid biosynthetic process 1.255896e-3
GO:0032714 negative regulation of interleukin-5 production 1.296513e-3
GO:0002074 extraocular skeletal muscle development 1.317312e-3
GO:0034259 negative regulation of Rho GTPase activity 1.317312e-3
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.317312e-3
GO:0072162 metanephric mesenchymal cell differentiation 1.318864e-3
GO:0045345 positive regulation of MHC class I biosynthetic process 1.326948e-3
GO:0016264 gap junction assembly 1.420839e-3
GO:0042703 menstruation 1.471683e-3
GO:0019101 female somatic sex determination 1.471683e-3
GO:0042375 quinone cofactor metabolic process 1.492657e-3
GO:0044240 multicellular organismal lipid catabolic process 1.495073e-3
GO:0051457 maintenance of protein location in nucleus 1.512755e-3
GO:0006349 regulation of gene expression by genetic imprinting 1.545177e-3
GO:0060707 trophoblast giant cell differentiation 1.574721e-3
GO:0051318 G1 phase 1.585760e-3
GO:0060816 random inactivation of X chromosome 1.676216e-3
GO:0050666 regulation of homocysteine metabolic process 1.679276e-3
GO:0016140 O-glycoside metabolic process 1.679276e-3
GO:0042723 thiamine-containing compound metabolic process 1.752526e-3
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 1.758095e-3
GO:0070194 synaptonemal complex disassembly 1.758095e-3
GO:0019448 L-cysteine catabolic process 1.758095e-3
GO:0006707 cholesterol catabolic process 1.762582e-3
GO:0001843 neural tube closure 1.784283e-3
GO:0009060 aerobic respiration 1.785091e-3
GO:0016142 O-glycoside catabolic process 1.799237e-3
GO:0006308 DNA catabolic process 1.832278e-3
GO:0044282 small molecule catabolic process 1.865351e-3
GO:0043921 modulation by host of viral transcription 1.876813e-3
GO:0040020 regulation of meiosis 1.886436e-3
GO:0035566 regulation of metanephros size 1.958247e-3
GO:0001778 plasma membrane repair 2.036233e-3
GO:0019556 histidine catabolic process to glutamate and formamide 2.036271e-3
GO:0008272 sulfate transport 2.154871e-3
GO:0021592 fourth ventricle development 2.183800e-3
GO:0003309 type B pancreatic cell differentiation 2.212420e-3
GO:0043114 regulation of vascular permeability 2.215894e-3
GO:0007006 mitochondrial membrane organization 2.227961e-3
GO:0031016 pancreas development 2.269540e-3
GO:0051567 histone H3-K9 methylation 2.280833e-3
GO:0043088 regulation of Cdc42 GTPase activity 2.287745e-3
GO:0003416 endochondral bone growth 2.301751e-3
GO:0021523 somatic motor neuron differentiation 2.316051e-3
GO:0090150 establishment of protein localization in membrane 2.316051e-3
GO:0045963 negative regulation of dopamine metabolic process 2.342858e-3
GO:0050668 positive regulation of homocysteine metabolic process 2.342858e-3
GO:0035445 borate transmembrane transport 2.342858e-3
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system 2.342858e-3
GO:0072595 maintenance of protein localization to organelle 2.350850e-3
GO:0042363 fat-soluble vitamin catabolic process 2.355590e-3
GO:0060338 regulation of type I interferon-mediated signaling pathway 2.377242e-3
GO:0001963 synaptic transmission, dopaminergic 2.378349e-3
GO:0010070 zygote asymmetric cell division 2.392971e-3
GO:0009451 RNA modification 2.411344e-3
GO:0060349 bone morphogenesis 2.419544e-3
GO:0006432 phenylalanyl-tRNA aminoacylation 2.444060e-3
GO:0001956 positive regulation of neurotransmitter secretion 2.518563e-3
GO:0001514 selenocysteine incorporation 2.518563e-3
GO:0045749 negative regulation of S phase of mitotic cell cycle 2.524726e-3
GO:0071930 negative regulation of transcription involved in G1/S phase of mitotic cell cycle 2.533825e-3
GO:0030322 stabilization of membrane potential 2.548308e-3
GO:0043653 mitochondrial fragmentation involved in apoptosis 2.591994e-3
GO:0060606 tube closure 2.603732e-3
GO:0018993 somatic sex determination 2.686704e-3
GO:0010890 positive regulation of sequestering of triglyceride 2.686704e-3
GO:0001757 somite specification 2.732237e-3
GO:0071899 negative regulation of estrogen receptor binding 2.743616e-3
GO:0072201 negative regulation of mesenchymal cell proliferation 2.822989e-3
GO:0006235 dTTP biosynthetic process 3.175026e-3
GO:0000088 mitotic prophase 3.175026e-3
GO:0006281 DNA repair 3.187843e-3
GO:0048708 astrocyte differentiation 3.248429e-3
GO:0030091 protein repair 3.308602e-3
GO:0060708 spongiotrophoblast differentiation 3.313400e-3
GO:0021943 formation of radial glial scaffolds 3.342953e-3
GO:0070245 positive regulation of thymocyte apoptosis 3.350424e-3
GO:0002066 columnar/cuboidal epithelial cell development 3.471363e-3
GO:0006364 rRNA processing 3.542117e-3
GO:0051131 chaperone-mediated protein complex assembly 3.604451e-3
GO:0006354 transcription elongation, DNA-dependent 3.605593e-3
GO:0042373 vitamin K metabolic process 3.620853e-3
GO:0002069 columnar/cuboidal epithelial cell maturation 3.620853e-3
GO:2000273 positive regulation of receptor activity 3.637647e-3
GO:0043973 histone H3-K4 acetylation 3.666939e-3
GO:0046985 positive regulation of hemoglobin biosynthetic process 3.666939e-3
GO:0043418 homocysteine catabolic process 3.666939e-3
GO:0006535 cysteine biosynthetic process from serine 3.666939e-3
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 3.666939e-3
GO:0019343 cysteine biosynthetic process via cystathionine 3.666939e-3
GO:0019346 transsulfuration 3.666939e-3
GO:0051965 positive regulation of synapse assembly 3.798162e-3
GO:0032288 myelin assembly 3.804657e-3
GO:0000012 single strand break repair 3.814695e-3
GO:0034959 endothelin maturation 3.818105e-3
GO:0010814 substance P catabolic process 3.818105e-3
GO:0010816 calcitonin catabolic process 3.818105e-3
GO:0010815 bradykinin catabolic process 3.848444e-3
GO:0016226 iron-sulfur cluster assembly 3.880309e-3
GO:0016048 detection of temperature stimulus 3.981468e-3
GO:0021535 cell migration in hindbrain 3.992981e-3
GO:0060056 mammary gland involution 4.039194e-3
GO:0045063 T-helper 1 cell differentiation 4.047163e-3
GO:0070831 basement membrane assembly 4.055689e-3
GO:0035646 endosome to melanosome transport 4.055689e-3
GO:0030683 evasion by virus of host immune response 4.055689e-3
GO:0045606 positive regulation of epidermal cell differentiation 4.222365e-3
GO:0071514 genetic imprinting 4.239023e-3
GO:0034660 ncRNA metabolic process 4.289876e-3
GO:0045343 regulation of MHC class I biosynthetic process 4.329382e-3
GO:0051445 regulation of meiotic cell cycle 4.450819e-3
GO:0010821 regulation of mitochondrion organization 4.463430e-3
GO:0046380 N-acetylneuraminate biosynthetic process 4.470944e-3
GO:0018192 enzyme active site formation via L-cysteine persulfide 4.470944e-3
GO:0016078 tRNA catabolic process 4.470944e-3
GO:0001682 tRNA 5'-leader removal 4.470944e-3
GO:0072668 tubulin complex biogenesis 4.484489e-3
GO:0055026 negative regulation of cardiac muscle tissue development 4.537521e-3
GO:0043570 maintenance of DNA repeat elements 4.598789e-3
GO:0033091 positive regulation of immature T cell proliferation 4.598789e-3
GO:0060689 cell differentiation involved in salivary gland development 4.709692e-3
GO:0001510 RNA methylation 4.789286e-3
GO:0033088 negative regulation of immature T cell proliferation in thymus 4.798655e-3
GO:0045409 negative regulation of interleukin-6 biosynthetic process 4.841376e-3
GO:2000077 negative regulation of type B pancreatic cell development 4.879112e-3
GO:0006422 aspartyl-tRNA aminoacylation 4.963485e-3
GO:0007339 binding of sperm to zona pellucida 4.980596e-3
GO:0007007 inner mitochondrial membrane organization 5.121094e-3
GO:0032107 regulation of response to nutrient levels 5.122115e-3
GO:0061384 heart trabecular morphogenesis 5.170921e-3
GO:0035922 foramen ovale closure 5.204853e-3
GO:0060577 pulmonary vein morphogenesis 5.204853e-3
GO:0003193 pulmonary valve formation 5.204853e-3
GO:0000354 cis assembly of pre-catalytic spliceosome 5.204853e-3
GO:0048703 embryonic viscerocranium morphogenesis 5.376634e-3
GO:0051187 cofactor catabolic process 5.439778e-3
GO:0008065 establishment of blood-nerve barrier 5.490247e-3
GO:0002071 glandular epithelial cell maturation 5.490247e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 5.496343e-3
GO:0045657 positive regulation of monocyte differentiation 5.526952e-3
GO:0021678 third ventricle development 5.631856e-3
GO:0045719 negative regulation of glycogen biosynthetic process 5.673295e-3
GO:0032656 regulation of interleukin-13 production 5.795642e-3
GO:0003344 pericardium morphogenesis 5.858073e-3
GO:0032696 negative regulation of interleukin-13 production 5.863814e-3
GO:0043923 positive regulation by host of viral transcription 5.922590e-3
GO:0007263 nitric oxide mediated signal transduction 6.026236e-3
GO:0060347 heart trabecula formation 6.029557e-3
GO:0051881 regulation of mitochondrial membrane potential 6.109305e-3
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 6.209422e-3
GO:0048103 somatic stem cell division 6.239644e-3
GO:0048821 erythrocyte development 6.280878e-3
GO:0032736 positive regulation of interleukin-13 production 6.291002e-3
GO:0060157 urinary bladder development 6.393375e-3
GO:0035567 non-canonical Wnt receptor signaling pathway 6.410188e-3
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 6.483082e-3
GO:0060580 ventral spinal cord interneuron fate determination 6.551789e-3
GO:0003327 type B pancreatic cell fate commitment 6.551789e-3
GO:0033484 nitric oxide homeostasis 6.668423e-3
GO:0019054 modulation by virus of host cellular process 6.754329e-3
GO:0006863 purine base transport 6.754329e-3
GO:0090193 positive regulation of glomerulus development 6.842156e-3
GO:0030223 neutrophil differentiation 6.882081e-3
GO:0034214 protein hexamerization 6.994868e-3
GO:0016072 rRNA metabolic process 7.050388e-3
GO:0090037 positive regulation of protein kinase C signaling cascade 7.057282e-3
GO:0019395 fatty acid oxidation 7.112773e-3
GO:0045200 establishment of neuroblast polarity 7.184079e-3
GO:0070368 positive regulation of hepatocyte differentiation 7.184079e-3
GO:0003310 pancreatic A cell differentiation 7.405260e-3
GO:0006361 transcription initiation from RNA polymerase I promoter 7.484408e-3
GO:0042989 sequestering of actin monomers 7.510934e-3
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 7.693570e-3
GO:2000035 regulation of stem cell division 7.915410e-3
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 8.000538e-3
GO:0021589 cerebellum structural organization 8.043661e-3
GO:0060904 regulation of protein folding in endoplasmic reticulum 8.043661e-3
GO:0035024 negative regulation of Rho protein signal transduction 8.087168e-3
GO:0060340 positive regulation of type I interferon-mediated signaling pathway 8.292905e-3
GO:0032717 negative regulation of interleukin-8 production 8.292905e-3
GO:0045658 regulation of neutrophil differentiation 8.428686e-3
GO:0009450 gamma-aminobutyric acid catabolic process 8.446790e-3
GO:0071425 hemopoietic stem cell proliferation 8.474720e-3
GO:0090002 establishment of protein localization in plasma membrane 8.596594e-3
GO:0070366 regulation of hepatocyte differentiation 8.631198e-3
GO:0000028 ribosomal small subunit assembly 8.771554e-3
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway 8.857425e-3
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin 8.867773e-3
GO:0051001 negative regulation of nitric-oxide synthase activity 8.908914e-3
GO:0046426 negative regulation of JAK-STAT cascade 8.917518e-3
GO:0032095 regulation of response to food 9.026306e-3
GO:0009109 coenzyme catabolic process 9.060382e-3
GO:0003100 regulation of systemic arterial blood pressure by endothelin 9.164069e-3
GO:0042538 hyperosmotic salinity response 9.168109e-3
GO:0044089 positive regulation of cellular component biogenesis 9.256021e-3
GO:0031063 regulation of histone deacetylation 9.256021e-3
GO:0043400 cortisol secretion 9.281445e-3
GO:0031275 regulation of lateral pseudopodium assembly 9.281445e-3
GO:0002572 pro-T cell differentiation 9.281445e-3
GO:0043922 negative regulation by host of viral transcription 9.282362e-3
GO:0010520 regulation of reciprocal meiotic recombination 9.484096e-3
GO:0043308 eosinophil degranulation 9.697473e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 9.697473e-3
GO:0007341 penetration of zona pellucida 9.846153e-3
GO:0018198 peptidyl-cysteine modification 9.874392e-3
GO:0032801 receptor catabolic process 9.911046e-3
GO:0060026 convergent extension 9.917935e-3
GO:0003065 positive regulation of heart rate by epinephrine 9.978304e-3
GO:0044062 regulation of excretion 9.992815e-3
GO:0002528 regulation of vascular permeability involved in acute inflammatory response 1.019925e-2
GO:0018023 peptidyl-lysine trimethylation 1.021658e-2
GO:0060744 mammary gland branching involved in thelarche 1.024395e-2
GO:0070234 positive regulation of T cell apoptosis 1.031763e-2
GO:0046621 negative regulation of organ growth 1.031763e-2
GO:0021506 anterior neuropore closure 1.042728e-2
GO:0014916 regulation of lung blood pressure 1.042728e-2
GO:0000266 mitochondrial fission 1.055072e-2
GO:0003062 regulation of heart rate by chemical signal 1.067130e-2
GO:0015780 nucleotide-sugar transport 1.072130e-2
GO:0071335 hair follicle cell proliferation 1.104622e-2
GO:0032290 peripheral nervous system myelin formation 1.104622e-2
GO:0019323 pentose catabolic process 1.104622e-2
GO:0051594 detection of glucose 1.106559e-2
GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process 1.114820e-2
GO:0044334 canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition 1.114820e-2
GO:0000239 pachytene 1.116043e-2
GO:0060376 positive regulation of mast cell differentiation 1.117437e-2
GO:0009202 deoxyribonucleoside triphosphate biosynthetic process 1.117437e-2
GO:0032469 endoplasmic reticulum calcium ion homeostasis 1.127732e-2
GO:0015696 ammonium transport 1.140920e-2
GO:0007127 meiosis I 1.149902e-2
GO:0090344 negative regulation of cell aging 1.159831e-2
GO:0006397 mRNA processing 1.177440e-2
GO:0048861 leukemia inhibitory factor signaling pathway 1.181275e-2
GO:0060299 negative regulation of sarcomere organization 1.184420e-2
GO:0033292 T-tubule organization 1.184420e-2
GO:0046491 L-methylmalonyl-CoA metabolic process 1.184420e-2
GO:0030851 granulocyte differentiation 1.188948e-2
GO:0032235 negative regulation of calcium ion transport via store-operated calcium channel activity 1.194075e-2
GO:0016559 peroxisome fission 1.194075e-2
GO:0014028 notochord formation 1.194075e-2
GO:0003184 pulmonary valve morphogenesis 1.194075e-2
GO:0070544 histone H3-K36 demethylation 1.200566e-2
GO:0022011 myelination in peripheral nervous system 1.201225e-2
GO:0003148 outflow tract septum morphogenesis 1.224328e-2
GO:0060041 retina development in camera-type eye 1.226092e-2
GO:0090140 regulation of mitochondrial fission 1.226200e-2
GO:0031167 rRNA methylation 1.226200e-2
GO:0060711 labyrinthine layer development 1.231267e-2
GO:0006261 DNA-dependent DNA replication 1.232816e-2
GO:0035813 regulation of renal sodium excretion 1.267282e-2
GO:0031557 induction of programmed cell death in response to chemical stimulus 1.272906e-2
GO:0042104 positive regulation of activated T cell proliferation 1.273710e-2
GO:0003323 type B pancreatic cell development 1.282063e-2
GO:0021623 oculomotor nerve formation 1.299943e-2
GO:0003409 optic cup structural organization 1.299943e-2
GO:0003404 optic vesicle morphogenesis 1.299943e-2
GO:0031134 sister chromatid biorientation 1.304120e-2
GO:0006423 cysteinyl-tRNA aminoacylation 1.304120e-2
GO:0035036 sperm-egg recognition 1.309895e-2
GO:0006297 nucleotide-excision repair, DNA gap filling 1.326024e-2
GO:0071895 odontoblast differentiation 1.345242e-2
GO:0003188 heart valve formation 1.351142e-2
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 1.358213e-2
GO:0034440 lipid oxidation 1.384545e-2
GO:0032926 negative regulation of activin receptor signaling pathway 1.413143e-2
GO:0048242 epinephrine secretion 1.423867e-2
GO:0016973 poly(A)+ mRNA export from nucleus 1.425876e-2
GO:0007340 acrosome reaction 1.435916e-2
GO:0035112 genitalia morphogenesis 1.439753e-2
GO:0006534 cysteine metabolic process 1.441663e-2
GO:0002829 negative regulation of type 2 immune response 1.441663e-2
GO:0006914 autophagy 1.456094e-2
GO:0043631 RNA polyadenylation 1.473872e-2
GO:0035082 axoneme assembly 1.492400e-2
GO:0006548 histidine catabolic process 1.494760e-2
GO:0010845 positive regulation of reciprocal meiotic recombination 1.498436e-2
GO:0035883 enteroendocrine cell differentiation 1.498436e-2
GO:0060611 mammary gland fat development 1.503545e-2
GO:0007020 microtubule nucleation 1.510852e-2
GO:0034110 regulation of homotypic cell-cell adhesion 1.525845e-2
GO:0045836 positive regulation of meiosis 1.545872e-2
GO:0010907 positive regulation of glucose metabolic process 1.567010e-2
GO:0035121 tail morphogenesis 1.585703e-2
GO:0090244 Wnt receptor signaling pathway involved in somitogenesis 1.585860e-2
GO:0051593 response to folic acid 1.595326e-2
GO:0016446 somatic hypermutation of immunoglobulin genes 1.606378e-2
GO:0006378 mRNA polyadenylation 1.611844e-2
GO:0045947 negative regulation of translational initiation 1.635085e-2
GO:0048793 pronephros development 1.637015e-2
GO:0015709 thiosulfate transport 1.652662e-2
GO:0071423 malate transmembrane transport 1.652662e-2
GO:0048291 isotype switching to IgG isotypes 1.652662e-2
GO:0010760 negative regulation of macrophage chemotaxis 1.652662e-2
GO:0002842 positive regulation of T cell mediated immune response to tumor cell 1.652662e-2
GO:0002368 B cell cytokine production 1.652662e-2
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.653442e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0031577 spindle checkpoint 7.100880e-9
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 2.347315e-8
GO:0007099 centriole replication 2.691364e-8
GO:0071174 mitotic cell cycle spindle checkpoint 1.750573e-7
GO:0006397 mRNA processing 2.162021e-7
GO:0071173 spindle assembly checkpoint 2.490136e-7
GO:0033344 cholesterol efflux 2.816096e-7
GO:0051298 centrosome duplication 3.700037e-7
GO:0034442 regulation of lipoprotein oxidation 3.761026e-7
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 5.182475e-7
GO:0007094 mitotic cell cycle spindle assembly checkpoint 5.470243e-7
GO:0030071 regulation of mitotic metaphase/anaphase transition 1.200662e-6
GO:0008380 RNA splicing 1.324337e-6
GO:0006260 DNA replication 1.392148e-6
GO:0033239 negative regulation of cellular amine metabolic process 1.404418e-6
GO:2000078 positive regulation of type B pancreatic cell development 1.831104e-6
GO:0035928 rRNA import into mitochondrion 1.831104e-6
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 2.236555e-6
GO:0032374 regulation of cholesterol transport 3.640968e-6
GO:0010900 negative regulation of phosphatidylcholine catabolic process 6.752776e-6
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 9.832160e-6
GO:0060299 negative regulation of sarcomere organization 9.832160e-6
GO:0043691 reverse cholesterol transport 1.079953e-5
GO:0033700 phospholipid efflux 1.079953e-5
GO:0034447 very-low-density lipoprotein particle clearance 1.783147e-5
GO:0000279 M phase 1.789297e-5
GO:0043457 regulation of cellular respiration 1.844125e-5
GO:0090244 Wnt receptor signaling pathway involved in somitogenesis 1.982710e-5
GO:0050748 negative regulation of lipoprotein metabolic process 2.002573e-5
GO:0006396 RNA processing 2.130126e-5
GO:0061181 regulation of chondrocyte development 2.151427e-5
GO:0032048 cardiolipin metabolic process 2.158678e-5
GO:0042697 menopause 2.963307e-5
GO:0071827 plasma lipoprotein particle organization 3.779367e-5
GO:0006476 protein deacetylation 3.961542e-5
GO:0007141 male meiosis I 4.245871e-5
GO:0042254 ribosome biogenesis 5.227668e-5
GO:0006982 response to lipid hydroperoxide 5.559580e-5
GO:0045647 negative regulation of erythrocyte differentiation 5.833147e-5
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 5.847458e-5
GO:0060217 hemangioblast cell differentiation 5.847458e-5
GO:0045799 positive regulation of chromatin assembly or disassembly 5.847458e-5
GO:0022417 protein maturation by protein folding 5.847458e-5
GO:0090343 positive regulation of cell aging 6.712054e-5
GO:0032368 regulation of lipid transport 7.286967e-5
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 7.504010e-5
GO:0035601 protein deacylation 7.915329e-5
GO:0051004 regulation of lipoprotein lipase activity 8.588391e-5
GO:0000305 response to oxygen radical 8.681979e-5
GO:0032049 cardiolipin biosynthetic process 9.125741e-5
GO:0031397 negative regulation of protein ubiquitination 9.363643e-5
GO:0046958 nonassociative learning 9.372165e-5
GO:0006302 double-strand break repair 9.814183e-5
GO:0045919 positive regulation of cytolysis 1.123465e-4
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway 1.123465e-4
GO:0040040 thermosensory behavior 1.123465e-4
GO:0007067 mitosis 1.144547e-4
GO:0022403 cell cycle phase 1.207438e-4
GO:0072560 type B pancreatic cell maturation 1.324701e-4
GO:0033037 polysaccharide localization 1.357915e-4
GO:0050746 regulation of lipoprotein metabolic process 1.385428e-4
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1.395515e-4
GO:0000087 M phase of mitotic cell cycle 1.493093e-4
GO:0061084 negative regulation of protein refolding 1.559279e-4
GO:0048285 organelle fission 1.609310e-4
GO:0055090 acylglycerol homeostasis 1.645052e-4
GO:0034369 plasma lipoprotein particle remodeling 1.708401e-4
GO:0007127 meiosis I 1.753323e-4
GO:0001579 medium-chain fatty acid transport 2.070683e-4
GO:0042157 lipoprotein metabolic process 2.091662e-4
GO:0019430 removal of superoxide radicals 2.113066e-4
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 2.131289e-4
GO:0070172 positive regulation of tooth mineralization 2.182061e-4
GO:0015920 lipopolysaccharide transport 2.196708e-4
GO:0090398 cellular senescence 2.210900e-4
GO:0060136 embryonic process involved in female pregnancy 2.309419e-4
GO:0007144 female meiosis I 2.380232e-4
GO:0060696 regulation of phospholipid catabolic process 2.453270e-4
GO:0046984 regulation of hemoglobin biosynthetic process 2.499301e-4
GO:0006235 dTTP biosynthetic process 2.697936e-4
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 2.697936e-4
GO:2000774 positive regulation of cellular senescence 3.038363e-4
GO:0090402 oncogene-induced senescence 3.038363e-4
GO:0035986 senescence-associated heterochromatin focus formation 3.038363e-4
GO:0007093 mitotic cell cycle checkpoint 3.175042e-4
GO:0006403 RNA localization 3.471088e-4
GO:0032532 regulation of microvillus length 3.488032e-4
GO:0060005 vestibular reflex 3.493065e-4
GO:0000303 response to superoxide 3.860243e-4
GO:0031334 positive regulation of protein complex assembly 3.862936e-4
GO:0006805 xenobiotic metabolic process 3.884051e-4
GO:0071711 basement membrane organization 3.921759e-4
GO:0006611 protein export from nucleus 3.981131e-4
GO:0097006 regulation of plasma lipoprotein particle levels 4.262929e-4
GO:0031507 heterochromatin formation 4.649294e-4
GO:0050684 regulation of mRNA processing 4.694866e-4
GO:0007098 centrosome cycle 4.697507e-4
GO:0060993 kidney morphogenesis 4.933822e-4
GO:0001935 endothelial cell proliferation 4.966010e-4
GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 4.978738e-4
GO:0046314 phosphocreatine biosynthetic process 5.033153e-4
GO:0051865 protein autoubiquitination 5.070217e-4
GO:0043243 positive regulation of protein complex disassembly 5.411768e-4
GO:0018009 N-terminal peptidyl-L-cysteine N-palmitoylation 5.439857e-4
GO:0043570 maintenance of DNA repeat elements 5.557299e-4
GO:0051725 protein de-ADP-ribosylation 5.656402e-4
GO:0043254 regulation of protein complex assembly 5.793126e-4
GO:0090161 Golgi ribbon formation 5.835010e-4
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 5.835010e-4
GO:0070602 regulation of centromeric sister chromatid cohesion 5.914937e-4
GO:0032530 regulation of microvillus organization 6.108237e-4
GO:0033211 adiponectin-mediated signaling pathway 6.152172e-4
GO:0006913 nucleocytoplasmic transport 6.179724e-4
GO:0051276 chromosome organization 6.192041e-4
GO:0003065 positive regulation of heart rate by epinephrine 6.197548e-4
GO:0046902 regulation of mitochondrial membrane permeability 6.666768e-4
GO:0046092 deoxycytidine metabolic process 6.854770e-4
GO:0060534 trachea cartilage development 6.936868e-4
GO:0033238 regulation of cellular amine metabolic process 6.960971e-4
GO:0031116 positive regulation of microtubule polymerization 7.056531e-4
GO:0016071 mRNA metabolic process 7.139441e-4
GO:0006281 DNA repair 7.372853e-4
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 7.444416e-4
GO:0046605 regulation of centrosome cycle 7.723057e-4
GO:0032271 regulation of protein polymerization 7.847886e-4
GO:0007129 synapsis 8.657930e-4
GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway 8.779121e-4
GO:0046853 inositol or phosphatidylinositol phosphorylation 8.779121e-4
GO:0032226 positive regulation of synaptic transmission, dopaminergic 8.779121e-4
GO:0071316 cellular response to nicotine 9.784361e-4
GO:0002227 innate immune response in mucosa 9.859373e-4
GO:0032423 regulation of mismatch repair 1.015055e-3
GO:0060669 embryonic placenta morphogenesis 1.050037e-3
GO:0035414 negative regulation of catenin import into nucleus 1.058164e-3
GO:0061156 pulmonary artery morphogenesis 1.066485e-3
GO:0051956 negative regulation of amino acid transport 1.066485e-3
GO:0031536 positive regulation of exit from mitosis 1.066485e-3
GO:0045837 negative regulation of membrane potential 1.071005e-3
GO:0045358 negative regulation of interferon-beta biosynthetic process 1.072958e-3
GO:0032383 regulation of intracellular cholesterol transport 1.072958e-3
GO:0015939 pantothenate metabolic process 1.072958e-3
GO:0018065 protein-cofactor linkage 1.085440e-3
GO:0051169 nuclear transport 1.104086e-3
GO:0048793 pronephros development 1.120347e-3
GO:0000432 positive regulation of transcription from RNA polymerase II promoter by glucose 1.144247e-3
GO:0042743 hydrogen peroxide metabolic process 1.197965e-3
GO:0051299 centrosome separation 1.224343e-3
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.224343e-3
GO:0007063 regulation of sister chromatid cohesion 1.228894e-3
GO:0009082 branched chain family amino acid biosynthetic process 1.271566e-3
GO:0000185 activation of MAPKKK activity 1.271566e-3
GO:0000070 mitotic sister chromatid segregation 1.379628e-3
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1.404048e-3
GO:0070192 chromosome organization involved in meiosis 1.425988e-3
GO:0060364 frontal suture morphogenesis 1.438286e-3
GO:0043973 histone H3-K4 acetylation 1.446702e-3
GO:0046985 positive regulation of hemoglobin biosynthetic process 1.446702e-3
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 1.446702e-3
GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine 1.446702e-3
GO:0042178 xenobiotic catabolic process 1.501533e-3
GO:0019255 glucose 1-phosphate metabolic process 1.530528e-3
GO:0019218 regulation of steroid metabolic process 1.558881e-3
GO:0045839 negative regulation of mitosis 1.607763e-3
GO:0051438 regulation of ubiquitin-protein ligase activity 1.640937e-3
GO:0030970 retrograde protein transport, ER to cytosol 1.654792e-3
GO:0051798 positive regulation of hair follicle development 1.683077e-3
GO:0018345 protein palmitoylation 1.704808e-3
GO:0033088 negative regulation of immature T cell proliferation in thymus 1.714472e-3
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 1.714472e-3
GO:0065005 protein-lipid complex assembly 1.722556e-3
GO:2000053 regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.733666e-3
GO:0072422 signal transduction involved in DNA damage checkpoint 1.741491e-3
GO:0048298 positive regulation of isotype switching to IgA isotypes 1.826232e-3
GO:0051340 regulation of ligase activity 1.894442e-3
GO:0090200 positive regulation of release of cytochrome c from mitochondria 1.906638e-3
GO:0046890 regulation of lipid biosynthetic process 1.929962e-3
GO:0051983 regulation of chromosome segregation 1.944059e-3
GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine 1.946604e-3
GO:0043922 negative regulation by host of viral transcription 1.969074e-3
GO:0071624 positive regulation of granulocyte chemotaxis 2.003050e-3
GO:0000085 G2 phase of mitotic cell cycle 2.018826e-3
GO:0050658 RNA transport 2.030542e-3
GO:0043523 regulation of neuron apoptosis 2.035018e-3
GO:0031113 regulation of microtubule polymerization 2.078392e-3
GO:0016032 viral reproduction 2.105309e-3
GO:0090312 positive regulation of protein deacetylation 2.126838e-3
GO:0071843 cellular component biogenesis at cellular level 2.211193e-3
GO:0018394 peptidyl-lysine acetylation 2.238910e-3
GO:0000819 sister chromatid segregation 2.250975e-3
GO:0042769 DNA damage response, detection of DNA damage 2.287320e-3
GO:0035855 megakaryocyte development 2.293460e-3
GO:0007346 regulation of mitotic cell cycle 2.304943e-3
GO:0032897 negative regulation of viral transcription 2.352151e-3
GO:0035802 adrenal cortex formation 2.353426e-3
GO:0072194 kidney smooth muscle tissue development 2.353426e-3
GO:0010948 negative regulation of cell cycle process 2.402244e-3
GO:0045717 negative regulation of fatty acid biosynthetic process 2.405212e-3
GO:0018393 internal peptidyl-lysine acetylation 2.480540e-3
GO:0051444 negative regulation of ubiquitin-protein ligase activity 2.501218e-3
GO:0018293 protein-FAD linkage 2.516108e-3
GO:0042228 interleukin-8 biosynthetic process 2.516108e-3
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 2.516108e-3
GO:0000379 tRNA-type intron splice site recognition and cleavage 2.516108e-3
GO:0071158 positive regulation of cell cycle arrest 2.614394e-3
GO:0018106 peptidyl-histidine phosphorylation 2.624079e-3
GO:0032508 DNA duplex unwinding 2.811341e-3
GO:0022402 cell cycle process 2.830407e-3
GO:0045940 positive regulation of steroid metabolic process 2.855806e-3
GO:0042304 regulation of fatty acid biosynthetic process 2.870817e-3
GO:0070925 organelle assembly 2.923250e-3
GO:0010467 gene expression 2.942747e-3
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 3.000285e-3
GO:0060535 trachea cartilage morphogenesis 3.018542e-3
GO:0001970 positive regulation of activation of membrane attack complex 3.018542e-3
GO:0031396 regulation of protein ubiquitination 3.037499e-3
GO:0043244 regulation of protein complex disassembly 3.070021e-3
GO:0033572 transferrin transport 3.070737e-3
GO:0071279 cellular response to cobalt ion 3.108172e-3
GO:0035356 cellular triglyceride homeostasis 3.108172e-3
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.108172e-3
GO:0010637 negative regulation of mitochondrial fusion 3.108172e-3
GO:0032077 positive regulation of deoxyribonuclease activity 3.108172e-3
GO:0032277 negative regulation of gonadotropin secretion 3.172033e-3
GO:0010898 positive regulation of triglyceride catabolic process 3.188591e-3
GO:0072180 mesonephric duct morphogenesis 3.278643e-3
GO:0051915 induction of synaptic plasticity by chemical substance 3.306542e-3
GO:0010824 regulation of centrosome duplication 3.306542e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 3.308581e-3
GO:0007168 receptor guanylyl cyclase signaling pathway 3.380407e-3
GO:0072098 anterior/posterior pattern specification involved in kidney development 3.384005e-3
GO:0048389 intermediate mesoderm development 3.384005e-3
GO:0002036 regulation of L-glutamate transport 3.384005e-3
GO:0006172 ADP biosynthetic process 3.384005e-3
GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity 3.494656e-3
GO:0006438 valyl-tRNA aminoacylation 3.494656e-3
GO:0043543 protein acylation 3.545914e-3
GO:0033108 mitochondrial respiratory chain complex assembly 3.595167e-3
GO:0006974 response to DNA damage stimulus 3.605464e-3
GO:0030432 peristalsis 3.684535e-3
GO:0051029 rRNA transport 3.762914e-3
GO:0030330 DNA damage response, signal transduction by p53 class mediator 3.842078e-3
GO:0032392 DNA geometric change 3.872776e-3
GO:0006606 protein import into nucleus 3.972965e-3
GO:0071156 regulation of cell cycle arrest 3.995739e-3
GO:0050689 negative regulation of defense response to virus by host 4.029210e-3
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 4.061351e-3
GO:0070669 response to interleukin-2 4.204157e-3
GO:0071281 cellular response to iron ion 4.204157e-3
GO:2001038 regulation of cellular response to drug 4.204157e-3
GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining 4.204157e-3
GO:2000685 positive regulation of cellular response to X-ray 4.204157e-3
GO:0035978 histone H2A-S139 phosphorylation 4.204157e-3
GO:0001306 age-dependent response to oxidative stress 4.204157e-3
GO:0035988 chondrocyte proliferation 4.204157e-3
GO:0003131 mesodermal-endodermal cell signaling 4.204157e-3
GO:0009202 deoxyribonucleoside triphosphate biosynthetic process 4.204157e-3
GO:0031052 chromosome breakage 4.204157e-3
GO:0051795 positive regulation of catagen 4.298002e-3
GO:0061162 establishment of monopolar cell polarity 4.314086e-3
GO:0003062 regulation of heart rate by chemical signal 4.439223e-3
GO:0007049 cell cycle 4.444906e-3
GO:0072331 signal transduction by p53 class mediator 4.532978e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 4.565721e-3
GO:0015696 ammonium transport 4.586638e-3
GO:2000772 regulation of cellular senescence 4.595275e-3
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 4.693873e-3
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 4.693873e-3
GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter 4.776268e-3
GO:0072362 regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter 4.776268e-3
GO:0061307 cardiac neural crest cell differentiation involved in heart development 4.872126e-3
GO:0071930 negative regulation of transcription involved in G1/S phase of mitotic cell cycle 4.875425e-3
GO:0003349 epicardium-derived cardiac endothelial cell differentiation 4.875425e-3
GO:0060084 synaptic transmission involved in micturition 4.981261e-3
GO:0034259 negative regulation of Rho GTPase activity 4.981261e-3
GO:0010918 positive regulation of mitochondrial membrane potential 4.981261e-3
GO:0045994 positive regulation of translational initiation by iron 4.987741e-3
GO:0061048 negative regulation of branching involved in lung morphogenesis 4.987741e-3
GO:0034116 positive regulation of heterotypic cell-cell adhesion 4.987741e-3
GO:0018242 protein O-linked glycosylation via serine 4.987741e-3
GO:0030221 basophil differentiation 4.987741e-3
GO:0002037 negative regulation of L-glutamate transport 4.987741e-3
GO:0018243 protein O-linked glycosylation via threonine 4.987741e-3
GO:0002385 mucosal immune response 4.999065e-3
GO:0017148 negative regulation of translation 5.098478e-3
GO:0060363 cranial suture morphogenesis 5.192309e-3
GO:0035404 histone-serine phosphorylation 5.198387e-3
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 5.249160e-3
GO:0045136 development of secondary sexual characteristics 5.262063e-3
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 5.311542e-3
GO:0018916 nitrobenzene metabolic process 5.311542e-3
GO:0071352 cellular response to interleukin-2 5.311542e-3
GO:0006497 protein lipidation 5.331264e-3
GO:0032367 intracellular cholesterol transport 5.332065e-3
GO:0033002 muscle cell proliferation 5.375519e-3
GO:0048818 positive regulation of hair follicle maturation 5.406037e-3
GO:0002149 hypochlorous acid biosynthetic process 5.406037e-3
GO:0060123 regulation of growth hormone secretion 5.424222e-3
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 5.486407e-3
GO:0072268 pattern specification involved in metanephros development 5.486407e-3
GO:0051170 nuclear import 5.553844e-3
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 5.581501e-3
GO:0072178 nephric duct morphogenesis 5.658985e-3
GO:0000724 double-strand break repair via homologous recombination 5.713901e-3
GO:0002328 pro-B cell differentiation 5.756009e-3
GO:0046543 development of secondary female sexual characteristics 5.917542e-3
GO:0048240 sperm capacitation 5.983617e-3
GO:0006984 ER-nucleus signaling pathway 6.075974e-3
GO:2000275 regulation of oxidative phosphorylation uncoupler activity 6.093999e-3
GO:0034227 tRNA thio-modification 6.093999e-3
GO:0016358 dendrite development 6.165911e-3
GO:0072088 nephron epithelium morphogenesis 6.169818e-3
GO:0007253 cytoplasmic sequestering of NF-kappaB 6.197023e-3
GO:0034384 high-density lipoprotein particle clearance 6.206206e-3
GO:0051135 positive regulation of NK T cell activation 6.265471e-3
GO:0051321 meiotic cell cycle 6.276243e-3
GO:0006475 internal protein amino acid acetylation 6.371092e-3
GO:0007080 mitotic metaphase plate congression 6.398421e-3
GO:0021675 nerve development 6.402640e-3
GO:0043526 neuroprotection 6.410156e-3
GO:0009410 response to xenobiotic stimulus 6.456372e-3
GO:0010822 positive regulation of mitochondrion organization 6.552164e-3
GO:0032057 negative regulation of translational initiation in response to stress 6.564815e-3
GO:0008611 ether lipid biosynthetic process 6.564815e-3
GO:0031129 inductive cell-cell signaling 6.564815e-3
GO:0002874 regulation of chronic inflammatory response to antigenic stimulus 6.644401e-3
GO:0046599 regulation of centriole replication 6.730979e-3
GO:0000052 citrulline metabolic process 6.730979e-3
GO:0006353 transcription termination, DNA-dependent 6.730979e-3
GO:0000075 cell cycle checkpoint 6.863324e-3
GO:0051006 positive regulation of lipoprotein lipase activity 6.955257e-3
GO:0019240 citrulline biosynthetic process 7.038787e-3
GO:0046931 pore complex assembly 7.057752e-3
GO:0000738 DNA catabolic process, exonucleolytic 7.110926e-3
GO:0031112 positive regulation of microtubule polymerization or depolymerization 7.204984e-3
GO:0021545 cranial nerve development 7.228179e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 7.302274e-3
GO:0000733 DNA strand renaturation 7.360649e-3
GO:0022613 ribonucleoprotein complex biogenesis 7.423814e-3
GO:0001969 regulation of activation of membrane attack complex 7.555866e-3
GO:0010872 regulation of cholesterol esterification 7.648212e-3
GO:2000172 regulation of branching morphogenesis of a nerve 7.783085e-3
GO:0042347 negative regulation of NF-kappaB import into nucleus 7.790375e-3
GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis 7.950339e-3
GO:0035095 behavioral response to nicotine 7.964286e-3
GO:0043461 proton-transporting ATP synthase complex assembly 7.964286e-3
GO:0006139 nucleobase-containing compound metabolic process 7.977825e-3
GO:0042744 hydrogen peroxide catabolic process 7.984220e-3
GO:0002251 organ or tissue specific immune response 8.087414e-3
GO:0070328 triglyceride homeostasis 8.197566e-3
GO:0007262 STAT protein import into nucleus 8.293542e-3
GO:0030301 cholesterol transport 8.400576e-3
GO:0007076 mitotic chromosome condensation 8.552008e-3
GO:0045069 regulation of viral genome replication 8.617160e-3
GO:0070997 neuron death 8.619886e-3
GO:0032516 positive regulation of phosphoprotein phosphatase activity 8.835802e-3
GO:2000384 negative regulation of ectoderm development 8.866289e-3
GO:0006268 DNA unwinding involved in replication 8.918346e-3
GO:0046015 regulation of transcription by glucose 8.927418e-3
GO:0090185 negative regulation of kidney development 8.959055e-3
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine 9.021747e-3
GO:0044260 cellular macromolecule metabolic process 9.065203e-3
GO:0051881 regulation of mitochondrial membrane potential 9.065946e-3
GO:0016573 histone acetylation 9.179602e-3
GO:0051402 neuron apoptosis 9.238638e-3
GO:0010984 regulation of lipoprotein particle clearance 9.287537e-3
GO:0006658 phosphatidylserine metabolic process 9.532512e-3
GO:0031065 positive regulation of histone deacetylation 9.627840e-3
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 9.666476e-3
GO:0000725 recombinational repair 9.743374e-3
GO:0008542 visual learning 9.748748e-3
GO:0072177 mesonephric duct development 9.825198e-3
GO:0008306 associative learning 9.842069e-3
GO:0042982 amyloid precursor protein metabolic process 9.994157e-3
GO:0070831 basement membrane assembly 1.008397e-2
GO:0038027 apolipoprotein A-I-mediated signaling pathway 1.008397e-2
GO:0008636 activation of caspase activity by protein phosphorylation 1.008397e-2
GO:0035409 histone H3-Y41 phosphorylation 1.008397e-2
GO:0072205 metanephric collecting duct development 1.008704e-2
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1.009589e-2
GO:0010939 regulation of necrotic cell death 1.011086e-2
GO:2000054 negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.014416e-2
GO:0048148 behavioral response to cocaine 1.014416e-2
GO:0051382 kinetochore assembly 1.018340e-2
GO:0071460 cellular response to cell-matrix adhesion 1.018340e-2
GO:0045329 carnitine biosynthetic process 1.018340e-2
GO:0003409 optic cup structural organization 1.024631e-2
GO:0021623 oculomotor nerve formation 1.024631e-2
GO:0003404 optic vesicle morphogenesis 1.024631e-2
GO:0006446 regulation of translational initiation 1.024924e-2
GO:0006818 hydrogen transport 1.028113e-2
GO:0071044 histone mRNA catabolic process 1.030667e-2
GO:0007260 tyrosine phosphorylation of STAT protein 1.055363e-2
GO:0006493 protein O-linked glycosylation 1.060249e-2
GO:0072176 nephric duct development 1.072677e-2
GO:0018205 peptidyl-lysine modification 1.091345e-2
GO:0015969 guanosine tetraphosphate metabolic process 1.096299e-2
GO:0007285 primary spermatocyte growth 1.096299e-2
GO:0006256 UDP catabolic process 1.096299e-2
GO:0060125 negative regulation of growth hormone secretion 1.107202e-2
GO:0071217 cellular response to external biotic stimulus 1.107202e-2
GO:0061015 snRNA import into nucleus 1.107202e-2
GO:0051463 negative regulation of cortisol secretion 1.107202e-2
GO:0007057 spindle assembly involved in female meiosis I 1.107202e-2
GO:0021771 lateral geniculate nucleus development 1.107202e-2
GO:0035502 metanephric ureteric bud development 1.107202e-2
GO:0006702 androgen biosynthetic process 1.121918e-2
GO:0045738 negative regulation of DNA repair 1.123253e-2
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.123253e-2
GO:0060018 astrocyte fate commitment 1.129681e-2
GO:0015986 ATP synthesis coupled proton transport 1.131394e-2
GO:0019048 virus-host interaction 1.149740e-2
GO:0018198 peptidyl-cysteine modification 1.165059e-2
GO:0060555 induction of necroptosis by extracellular signals 1.189282e-2
GO:0061312 BMP signaling pathway involved in heart development 1.189282e-2
GO:0045654 positive regulation of megakaryocyte differentiation 1.189282e-2
GO:0032497 detection of lipopolysaccharide 1.189282e-2
GO:0048630 skeletal muscle tissue growth 1.196593e-2
GO:0072593 reactive oxygen species metabolic process 1.205438e-2
GO:0006364 rRNA processing 1.216031e-2
GO:0044065 regulation of respiratory system process 1.218701e-2
GO:0008635 activation of caspase activity by cytochrome c 1.236650e-2
GO:0007064 mitotic sister chromatid cohesion 1.245653e-2
GO:0031440 regulation of mRNA 3'-end processing 1.245653e-2
GO:0060218 hemopoietic stem cell differentiation 1.248280e-2
GO:0045869 negative regulation of retroviral genome replication 1.251287e-2
GO:0034088 maintenance of mitotic sister chromatid cohesion 1.251287e-2
GO:0090342 regulation of cell aging 1.284811e-2
GO:0009437 carnitine metabolic process 1.293894e-2
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 1.295811e-2
GO:0032202 telomere assembly 1.295811e-2
GO:0003130 BMP signaling pathway involved in heart induction 1.295811e-2
GO:0032981 mitochondrial respiratory chain complex I assembly 1.340050e-2
GO:0031442 positive regulation of mRNA 3'-end processing 1.340050e-2
GO:0007618 mating 1.346356e-2
GO:0043484 regulation of RNA splicing 1.365835e-2
GO:0008629 induction of apoptosis by intracellular signals 1.373298e-2
GO:0060670 branching involved in embryonic placenta morphogenesis 1.390493e-2
GO:0007091 mitotic metaphase/anaphase transition 1.392116e-2
GO:0001672 regulation of chromatin assembly or disassembly 1.392116e-2
GO:0019098 reproductive behavior 1.398604e-2
GO:0042758 long-chain fatty acid catabolic process 1.412473e-2
GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport 1.412473e-2
GO:0042413 carnitine catabolic process 1.412473e-2
GO:0010501 RNA secondary structure unwinding 1.412473e-2
GO:0006498 N-terminal protein lipidation 1.412473e-2
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.416471e-2
GO:0031627 telomeric loop formation 1.416579e-2
GO:0000237 leptotene 1.416579e-2
GO:0071577 zinc ion transmembrane transport 1.438948e-2
GO:0035261 external genitalia morphogenesis 1.448753e-2
GO:0072161 mesenchymal cell differentiation involved in kidney development 1.452328e-2
GO:0021557 oculomotor nerve development 1.452328e-2
GO:0071385 cellular response to glucocorticoid stimulus 1.456542e-2
GO:0072210 metanephric nephron development 1.457787e-2
GO:0030837 negative regulation of actin filament polymerization 1.470187e-2
GO:0007096 regulation of exit from mitosis 1.474408e-2
GO:0061046 regulation of branching involved in lung morphogenesis 1.474408e-2
GO:0035912 dorsal aorta morphogenesis 1.475946e-2
GO:0030038 contractile actin filament bundle assembly 1.475946e-2
GO:0009107 lipoate biosynthetic process 1.475946e-2
GO:0008216 spermidine metabolic process 1.475946e-2
GO:2000018 regulation of male gonad development 1.476452e-2
GO:0007220 Notch receptor processing 1.476452e-2
GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis 1.484063e-2
GO:0051693 actin filament capping 1.488494e-2
GO:0060557 positive regulation of vitamin D biosynthetic process 1.493441e-2
GO:0090304 nucleic acid metabolic process 1.510878e-2
GO:0010498 proteasomal protein catabolic process 1.524709e-2
GO:0072028 nephron morphogenesis 1.550938e-2
GO:0000278 mitotic cell cycle 1.560497e-2
GO:0006417 regulation of translation 1.583420e-2
GO:2000020 positive regulation of male gonad development 1.591276e-2
GO:0035176 social behavior 1.598226e-2
GO:0015992 proton transport 1.606025e-2
GO:0016575 histone deacetylation 1.610681e-2
GO:0017038 protein import 1.623758e-2
GO:0050925 negative regulation of negative chemotaxis 1.625637e-2
GO:0051443 positive regulation of ubiquitin-protein ligase activity 1.637305e-2
GO:0050881 musculoskeletal movement 1.640454e-2
GO:0000381 regulation of alternative nuclear mRNA splicing, via spliceosome 1.652771e-2
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 1.654573e-2
GO:0006829 zinc ion transport 1.668240e-2
GO:0032490 detection of molecule of bacterial origin 1.678670e-2
GO:0021554 optic nerve development 1.681218e-2
GO:0033554 cellular response to stress 1.684630e-2
GO:0006473 protein acetylation 1.690717e-2
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 1.699946e-2
GO:0010724 regulation of definitive erythrocyte differentiation 1.706803e-2
GO:0006284 base-excision repair 1.714449e-2
GO:0071071 regulation of phospholipid biosynthetic process 1.727025e-2
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 1.733827e-2
GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine 1.739727e-2
GO:0070584 mitochondrion morphogenesis 1.752574e-2
GO:0007569 cell aging 1.767814e-2
GO:0001662 behavioral fear response 1.776421e-2
GO:0045922 negative regulation of fatty acid metabolic process 1.776960e-2
GO:0030834 regulation of actin filament depolymerization 1.779072e-2
GO:0032375 negative regulation of cholesterol transport 1.794138e-2
GO:0071549 cellular response to dexamethasone stimulus 1.816871e-2
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 1.823250e-2