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Novel motif:59

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name:motif59_NCWCCARNR

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0032526 response to retinoic acid 2.609589e-15
GO:0060351 cartilage development involved in endochondral bone morphogenesis 5.346251e-15
GO:0035814 negative regulation of renal sodium excretion 1.223747e-14
GO:0071300 cellular response to retinoic acid 1.870068e-14
GO:0034505 tooth mineralization 3.854085e-14
GO:0071299 cellular response to vitamin A 4.820250e-13
GO:0060346 bone trabecula formation 7.098297e-13
GO:0002149 hypochlorous acid biosynthetic process 7.228875e-13
GO:0044130 negative regulation of growth of symbiont in host 1.436921e-12
GO:0031670 cellular response to nutrient 2.533134e-12
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 4.118366e-12
GO:0048873 homeostasis of number of cells within a tissue 4.441792e-12
GO:0010718 positive regulation of epithelial to mesenchymal transition 1.002205e-11
GO:0010717 regulation of epithelial to mesenchymal transition 1.236815e-11
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 1.337875e-11
GO:0006959 humoral immune response 1.437259e-11
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1.547443e-11
GO:0006927 transformed cell apoptosis 2.485054e-11
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 2.588332e-11
GO:0060124 positive regulation of growth hormone secretion 5.148628e-11
GO:0002679 respiratory burst involved in defense response 6.885544e-11
GO:0001957 intramembranous ossification 1.620324e-10
GO:0033209 tumor necrosis factor-mediated signaling pathway 2.538095e-10
GO:0044062 regulation of excretion 5.984364e-10
GO:0033189 response to vitamin A 6.277611e-10
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 6.478758e-10
GO:0060343 trabecula formation 8.190565e-10
GO:0035691 macrophage migration inhibitory factor signaling pathway 1.047739e-9
GO:0042542 response to hydrogen peroxide 1.058984e-9
GO:0071295 cellular response to vitamin 1.129172e-9
GO:0007586 digestion 1.395049e-9
GO:0061383 trabecula morphogenesis 1.556585e-9
GO:0006768 biotin metabolic process 1.780476e-9
GO:0008078 mesodermal cell migration 1.786232e-9
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 2.626533e-9
GO:0019884 antigen processing and presentation of exogenous antigen 3.965260e-9
GO:0019276 UDP-N-acetylgalactosamine metabolic process 4.491654e-9
GO:0051956 negative regulation of amino acid transport 4.835694e-9
GO:0007162 negative regulation of cell adhesion 6.043908e-9
GO:0042488 positive regulation of odontogenesis of dentine-containing tooth 7.013274e-9
GO:0019883 antigen processing and presentation of endogenous antigen 7.430104e-9
GO:0051488 activation of anaphase-promoting complex activity 8.623501e-9
GO:0002443 leukocyte mediated immunity 1.064061e-8
GO:0030198 extracellular matrix organization 1.347263e-8
GO:0000302 response to reactive oxygen species 1.444244e-8
GO:0030277 maintenance of gastrointestinal epithelium 1.450506e-8
GO:0002037 negative regulation of L-glutamate transport 1.495525e-8
GO:0045994 positive regulation of translational initiation by iron 1.495525e-8
GO:0002920 regulation of humoral immune response 1.556507e-8
GO:0035813 regulation of renal sodium excretion 1.564148e-8
GO:0010985 negative regulation of lipoprotein particle clearance 1.616259e-8
GO:0000389 nuclear mRNA 3'-splice site recognition 1.661723e-8
GO:0006447 regulation of translational initiation by iron 1.723149e-8
GO:0002449 lymphocyte mediated immunity 1.781039e-8
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1.927149e-8
GO:0031536 positive regulation of exit from mitosis 1.944321e-8
GO:0046730 induction of host immune response by virus 1.944321e-8
GO:0060611 mammary gland fat development 2.049597e-8
GO:0033273 response to vitamin 2.066963e-8
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 2.320263e-8
GO:0035854 eosinophil fate commitment 2.330988e-8
GO:0030222 eosinophil differentiation 2.330988e-8
GO:0060444 branching involved in mammary gland duct morphogenesis 2.484385e-8
GO:0002478 antigen processing and presentation of exogenous peptide antigen 2.580480e-8
GO:0043901 negative regulation of multi-organism process 3.110329e-8
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 3.155531e-8
GO:0019724 B cell mediated immunity 3.201054e-8
GO:0002830 positive regulation of type 2 immune response 5.526638e-8
GO:0002718 regulation of cytokine production involved in immune response 5.584966e-8
GO:0016064 immunoglobulin mediated immune response 6.795909e-8
GO:0030851 granulocyte differentiation 7.026701e-8
GO:0050832 defense response to fungus 7.619502e-8
GO:0021879 forebrain neuron differentiation 7.680328e-8
GO:0042696 menarche 7.842984e-8
GO:0045630 positive regulation of T-helper 2 cell differentiation 8.176929e-8
GO:0001894 tissue homeostasis 8.429143e-8
GO:0051241 negative regulation of multicellular organismal process 8.522587e-8
GO:0043586 tongue development 9.527007e-8
GO:0048708 astrocyte differentiation 1.065080e-7
GO:0060014 granulosa cell differentiation 1.068782e-7
GO:0046732 active induction of host immune response by virus 1.512719e-7
GO:0070208 protein heterotrimerization 1.602406e-7
GO:0002712 regulation of B cell mediated immunity 1.756723e-7
GO:0009651 response to salt stress 1.817048e-7
GO:0022408 negative regulation of cell-cell adhesion 1.853715e-7
GO:0032964 collagen biosynthetic process 1.890279e-7
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.894937e-7
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 2.121848e-7
GO:0048872 homeostasis of number of cells 2.210755e-7
GO:0042503 tyrosine phosphorylation of Stat3 protein 2.364867e-7
GO:0045651 positive regulation of macrophage differentiation 2.391137e-7
GO:0002074 extraocular skeletal muscle development 2.913232e-7
GO:0032689 negative regulation of interferon-gamma production 3.078333e-7
GO:0002016 regulation of blood volume by renin-angiotensin 3.102576e-7
GO:0030206 chondroitin sulfate biosynthetic process 3.190404e-7
GO:0002889 regulation of immunoglobulin mediated immune response 3.282231e-7
GO:0030852 regulation of granulocyte differentiation 3.735557e-7
GO:0042506 tyrosine phosphorylation of Stat5 protein 3.833596e-7
GO:0043542 endothelial cell migration 3.864763e-7
GO:0032673 regulation of interleukin-4 production 3.969889e-7
GO:0045059 positive thymic T cell selection 4.050751e-7
GO:0003073 regulation of systemic arterial blood pressure 4.385521e-7
GO:0043206 fibril organization 4.688651e-7
GO:0061048 negative regulation of branching involved in lung morphogenesis 4.909427e-7
GO:0010900 negative regulation of phosphatidylcholine catabolic process 4.909427e-7
GO:0002678 positive regulation of chronic inflammatory response 5.023695e-7
GO:0045649 regulation of macrophage differentiation 5.031282e-7
GO:0002455 humoral immune response mediated by circulating immunoglobulin 5.162423e-7
GO:0007617 mating behavior 5.550256e-7
GO:0071356 cellular response to tumor necrosis factor 5.628010e-7
GO:0045835 negative regulation of meiosis 5.893357e-7
GO:0021892 cerebral cortex GABAergic interneuron differentiation 7.352627e-7
GO:0031297 replication fork processing 8.524718e-7
GO:0007509 mesoderm migration involved in gastrulation 8.875092e-7
GO:0001990 regulation of systemic arterial blood pressure by hormone 9.958984e-7
GO:0030826 regulation of cGMP biosynthetic process 1.008267e-6
GO:0032753 positive regulation of interleukin-4 production 1.009744e-6
GO:0006958 complement activation, classical pathway 1.037154e-6
GO:0009605 response to external stimulus 1.050420e-6
GO:0003417 growth plate cartilage development 1.134058e-6
GO:2000021 regulation of ion homeostasis 1.198773e-6
GO:0006956 complement activation 1.236583e-6
GO:0002828 regulation of type 2 immune response 1.356987e-6
GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 1.368759e-6
GO:0002339 B cell selection 1.545229e-6
GO:0051533 positive regulation of NFAT protein import into nucleus 1.594645e-6
GO:0048341 paraxial mesoderm formation 1.659375e-6
GO:0007589 body fluid secretion 1.690020e-6
GO:0010984 regulation of lipoprotein particle clearance 1.789818e-6
GO:0042074 cell migration involved in gastrulation 1.909590e-6
GO:0002761 regulation of myeloid leukocyte differentiation 1.974287e-6
GO:0051798 positive regulation of hair follicle development 2.119515e-6
GO:0030037 actin filament reorganization involved in cell cycle 2.170790e-6
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 2.171818e-6
GO:0042363 fat-soluble vitamin catabolic process 2.218189e-6
GO:0060419 heart growth 2.322177e-6
GO:0002906 negative regulation of mature B cell apoptosis 2.479643e-6
GO:0050868 negative regulation of T cell activation 2.481795e-6
GO:0021872 forebrain generation of neurons 2.502332e-6
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 2.505939e-6
GO:0048771 tissue remodeling 2.548089e-6
GO:0051291 protein heterooligomerization 2.838356e-6
GO:0002579 positive regulation of antigen processing and presentation 2.905937e-6
GO:0070670 response to interleukin-4 3.178365e-6
GO:0010669 epithelial structure maintenance 3.186539e-6
GO:0060160 negative regulation of dopamine receptor signaling pathway 3.562995e-6
GO:0002252 immune effector process 3.567038e-6
GO:0048145 regulation of fibroblast proliferation 3.701148e-6
GO:0070345 negative regulation of fat cell proliferation 3.741989e-6
GO:0003009 skeletal muscle contraction 3.742802e-6
GO:0043029 T cell homeostasis 3.958685e-6
GO:0055017 cardiac muscle tissue growth 4.116340e-6
GO:0021542 dentate gyrus development 4.182604e-6
GO:0042744 hydrogen peroxide catabolic process 4.371286e-6
GO:0045123 cellular extravasation 4.418579e-6
GO:0002250 adaptive immune response 4.526726e-6
GO:0045581 negative regulation of T cell differentiation 4.537790e-6
GO:0002344 B cell affinity maturation 4.654120e-6
GO:0055070 copper ion homeostasis 5.012529e-6
GO:0002861 regulation of inflammatory response to antigenic stimulus 5.022457e-6
GO:0006551 leucine metabolic process 5.072583e-6
GO:0045684 positive regulation of epidermis development 5.298095e-6
GO:0006878 cellular copper ion homeostasis 5.371022e-6
GO:0032862 activation of Rho GTPase activity 5.529163e-6
GO:0045112 integrin biosynthetic process 5.753790e-6
GO:0045061 thymic T cell selection 5.783928e-6
GO:0010994 free ubiquitin chain polymerization 6.151561e-6
GO:0045580 regulation of T cell differentiation 6.223682e-6
GO:0042703 menstruation 6.229503e-6
GO:0019101 female somatic sex determination 6.229503e-6
GO:0060350 endochondral bone morphogenesis 6.537810e-6
GO:0060430 lung saccule development 6.640578e-6
GO:0008217 regulation of blood pressure 6.785898e-6
GO:0002922 positive regulation of humoral immune response 6.852085e-6
GO:0032736 positive regulation of interleukin-13 production 7.028991e-6
GO:0003416 endochondral bone growth 7.047226e-6
GO:0006884 cell volume homeostasis 7.356015e-6
GO:0060123 regulation of growth hormone secretion 7.379186e-6
GO:0007584 response to nutrient 8.051744e-6
GO:0019098 reproductive behavior 8.137688e-6
GO:0021759 globus pallidus development 9.353015e-6
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 9.448842e-6
GO:0032863 activation of Rac GTPase activity 9.448842e-6
GO:0002891 positive regulation of immunoglobulin mediated immune response 9.987423e-6
GO:0051788 response to misfolded protein 1.011996e-5
GO:0048730 epidermis morphogenesis 1.090888e-5
GO:0048298 positive regulation of isotype switching to IgA isotypes 1.145613e-5
GO:0051955 regulation of amino acid transport 1.163948e-5
GO:0035572 N-terminal peptidyl-serine dimethylation 1.243425e-5
GO:0035573 N-terminal peptidyl-serine trimethylation 1.243425e-5
GO:0018016 N-terminal peptidyl-proline dimethylation 1.243425e-5
GO:0018012 N-terminal peptidyl-alanine trimethylation 1.243425e-5
GO:0050909 sensory perception of taste 1.256389e-5
GO:0032720 negative regulation of tumor necrosis factor production 1.284800e-5
GO:0042476 odontogenesis 1.298945e-5
GO:0009817 defense response to fungus, incompatible interaction 1.310333e-5
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1.310333e-5
GO:0030952 establishment or maintenance of cytoskeleton polarity 1.372211e-5
GO:0002700 regulation of production of molecular mediator of immune response 1.470539e-5
GO:0001878 response to yeast 1.531811e-5
GO:0090218 positive regulation of lipid kinase activity 1.534073e-5
GO:0031667 response to nutrient levels 1.540759e-5
GO:0030322 stabilization of membrane potential 1.666922e-5
GO:0071316 cellular response to nicotine 1.682374e-5
GO:0034616 response to laminar fluid shear stress 1.685676e-5
GO:0050902 leukocyte adhesive activation 1.725556e-5
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 1.725556e-5
GO:0002019 regulation of renal output by angiotensin 1.725556e-5
GO:0015760 glucose-6-phosphate transport 1.728892e-5
GO:0060557 positive regulation of vitamin D biosynthetic process 1.817517e-5
GO:2000107 negative regulation of leukocyte apoptosis 1.886590e-5
GO:0045619 regulation of lymphocyte differentiation 1.896663e-5
GO:0048384 retinoic acid receptor signaling pathway 2.025206e-5
GO:0046543 development of secondary female sexual characteristics 2.133216e-5
GO:0042482 positive regulation of odontogenesis 2.157545e-5
GO:0002921 negative regulation of humoral immune response 2.157545e-5
GO:0060251 regulation of glial cell proliferation 2.348587e-5
GO:0009235 cobalamin metabolic process 2.414603e-5
GO:0085018 maintenance of symbiont-containing vacuole via substance secreted by host 2.500105e-5
GO:0035378 carbon dioxide transmembrane transport 2.500105e-5
GO:0035377 transepithelial water transport 2.500105e-5
GO:0030950 establishment or maintenance of actin cytoskeleton polarity 2.500105e-5
GO:0035265 organ growth 2.581099e-5
GO:0002026 regulation of the force of heart contraction 2.637847e-5
GO:0045060 negative thymic T cell selection 2.648785e-5
GO:0045338 farnesyl diphosphate metabolic process 2.677141e-5
GO:0001974 blood vessel remodeling 2.741943e-5
GO:0051591 response to cAMP 2.874847e-5
GO:0045109 intermediate filament organization 3.051853e-5
GO:0042487 regulation of odontogenesis of dentine-containing tooth 3.053429e-5
GO:0022010 central nervous system myelination 3.198713e-5
GO:0071529 cementum mineralization 3.281612e-5
GO:0071803 positive regulation of podosome assembly 3.436371e-5
GO:0071071 regulation of phospholipid biosynthetic process 3.485846e-5
GO:0009303 rRNA transcription 3.513883e-5
GO:0061153 trachea gland development 3.527514e-5
GO:0002903 negative regulation of B cell apoptosis 3.815632e-5
GO:0042743 hydrogen peroxide metabolic process 3.838603e-5
GO:0007635 chemosensory behavior 3.899212e-5
GO:0071732 cellular response to nitric oxide 4.008251e-5
GO:0090361 regulation of platelet-derived growth factor production 4.454115e-5
GO:0007009 plasma membrane organization 4.532080e-5
GO:0045655 regulation of monocyte differentiation 4.537075e-5
GO:0021877 forebrain neuron fate commitment 4.807267e-5
GO:0042391 regulation of membrane potential 4.918027e-5
GO:0006066 alcohol metabolic process 4.939929e-5
GO:0060349 bone morphogenesis 5.052690e-5
GO:0010719 negative regulation of epithelial to mesenchymal transition 5.105034e-5
GO:0002676 regulation of chronic inflammatory response 5.329121e-5
GO:0009225 nucleotide-sugar metabolic process 5.337330e-5
GO:0040018 positive regulation of multicellular organism growth 5.410312e-5
GO:0010388 cullin deneddylation 5.763739e-5
GO:0071072 negative regulation of phospholipid biosynthetic process 5.920106e-5
GO:0008544 epidermis development 5.925392e-5
GO:0031282 regulation of guanylate cyclase activity 6.121205e-5
GO:0002036 regulation of L-glutamate transport 6.159115e-5
GO:0044070 regulation of anion transport 6.170501e-5
GO:0035048 splicing factor protein import into nucleus 6.233200e-5
GO:0034653 retinoic acid catabolic process 6.270737e-5
GO:0045657 positive regulation of monocyte differentiation 6.287806e-5
GO:0043526 neuroprotection 6.358398e-5
GO:0017148 negative regulation of translation 6.371567e-5
GO:0046325 negative regulation of glucose import 6.534340e-5
GO:0035419 activation of MAPK activity involved in innate immune response 6.535223e-5
GO:0022600 digestive system process 6.655298e-5
GO:0060133 somatotropin secreting cell development 7.108128e-5
GO:0014002 astrocyte development 7.327179e-5
GO:0002902 regulation of B cell apoptosis 7.327179e-5
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 7.610561e-5
GO:0045637 regulation of myeloid cell differentiation 7.821407e-5
GO:0022601 menstrual cycle phase 7.835253e-5
GO:0051156 glucose 6-phosphate metabolic process 7.939340e-5
GO:0009416 response to light stimulus 8.011392e-5
GO:0014806 smooth muscle hyperplasia 8.201661e-5
GO:0055069 zinc ion homeostasis 8.546468e-5
GO:0002522 leukocyte migration involved in immune response 8.555470e-5
GO:0006244 pyrimidine nucleotide catabolic process 8.572848e-5
GO:0045662 negative regulation of myoblast differentiation 8.818988e-5
GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure 8.847886e-5
GO:0046339 diacylglycerol metabolic process 9.333803e-5
GO:0000712 resolution of meiotic recombination intermediates 9.415356e-5
GO:0008065 establishment of blood-nerve barrier 9.523703e-5
GO:0010624 regulation of Schwann cell proliferation 9.542619e-5
GO:0045414 regulation of interleukin-8 biosynthetic process 1.002213e-4
GO:0044154 histone H3-K14 acetylation 1.019256e-4
GO:0002573 myeloid leukocyte differentiation 1.019681e-4
GO:0051148 negative regulation of muscle cell differentiation 1.025750e-4
GO:0043368 positive T cell selection 1.036631e-4
GO:0002209 behavioral defense response 1.051562e-4
GO:0042538 hyperosmotic salinity response 1.071912e-4
GO:0048469 cell maturation 1.082103e-4
GO:0051270 regulation of cellular component movement 1.109662e-4
GO:0072109 glomerular mesangium development 1.111419e-4
GO:0021984 adenohypophysis development 1.128678e-4
GO:0033081 regulation of T cell differentiation in thymus 1.131996e-4
GO:0001818 negative regulation of cytokine production 1.146134e-4
GO:0010511 regulation of phosphatidylinositol biosynthetic process 1.151716e-4
GO:0048382 mesendoderm development 1.153524e-4
GO:0048340 paraxial mesoderm morphogenesis 1.178437e-4
GO:0033327 Leydig cell differentiation 1.196730e-4
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 1.206337e-4
GO:0009191 ribonucleoside diphosphate catabolic process 1.206337e-4
GO:0006285 base-excision repair, AP site formation 1.206337e-4
GO:0009298 GDP-mannose biosynthetic process 1.219245e-4
GO:0001826 inner cell mass cell differentiation 1.219245e-4
GO:0060396 growth hormone receptor signaling pathway 1.239627e-4
GO:0045556 positive regulation of TRAIL biosynthetic process 1.240171e-4
GO:0046032 ADP catabolic process 1.248117e-4
GO:0046709 IDP catabolic process 1.248117e-4
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.248970e-4
GO:0060591 chondroblast differentiation 1.253973e-4
GO:0006829 zinc ion transport 1.273411e-4
GO:0043627 response to estrogen stimulus 1.274987e-4
GO:0043585 nose morphogenesis 1.292882e-4
GO:0032754 positive regulation of interleukin-5 production 1.379737e-4
GO:0045638 negative regulation of myeloid cell differentiation 1.386102e-4
GO:0022407 regulation of cell-cell adhesion 1.386106e-4
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 1.394412e-4
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1.394412e-4
GO:0060038 cardiac muscle cell proliferation 1.399283e-4
GO:0016264 gap junction assembly 1.399547e-4
GO:0001649 osteoblast differentiation 1.404590e-4
GO:0035307 positive regulation of protein dephosphorylation 1.423738e-4
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.466287e-4
GO:0060456 positive regulation of digestive system process 1.527283e-4
GO:0010742 macrophage derived foam cell differentiation 1.527283e-4
GO:0039020 pronephric nephron tubule development 1.540437e-4
GO:0035565 regulation of pronephros size 1.540437e-4
GO:0045948 positive regulation of translational initiation 1.541998e-4
GO:0051272 positive regulation of cellular component movement 1.558429e-4
GO:0001662 behavioral fear response 1.601519e-4
GO:0008643 carbohydrate transport 1.622137e-4
GO:0002513 tolerance induction to self antigen 1.655073e-4
GO:0045471 response to ethanol 1.671652e-4
GO:0060763 mammary duct terminal end bud growth 1.675974e-4
GO:0022614 membrane to membrane docking 1.676393e-4
GO:0051438 regulation of ubiquitin-protein ligase activity 1.687355e-4
GO:0009264 deoxyribonucleotide catabolic process 1.699075e-4
GO:0050863 regulation of T cell activation 1.701456e-4
GO:0032088 negative regulation of NF-kappaB transcription factor activity 1.705850e-4
GO:0034405 response to fluid shear stress 1.724494e-4
GO:0045136 development of secondary sexual characteristics 1.749857e-4
GO:0060751 branch elongation involved in mammary gland duct branching 1.803998e-4
GO:0052565 response to defense-related host nitric oxide production 1.824686e-4
GO:0030334 regulation of cell migration 1.831630e-4
GO:0001906 cell killing 1.832977e-4
GO:0051764 actin crosslink formation 1.838956e-4
GO:0033002 muscle cell proliferation 1.873568e-4
GO:0060693 regulation of branching involved in salivary gland morphogenesis 1.895043e-4
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.895043e-4
GO:0018350 protein esterification 1.901639e-4
GO:0044258 intestinal lipid catabolic process 1.901639e-4
GO:0042093 T-helper cell differentiation 1.914389e-4
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 1.936375e-4
GO:0035313 wound healing, spreading of epidermal cells 1.949584e-4
GO:0043266 regulation of potassium ion transport 1.962860e-4
GO:0042508 tyrosine phosphorylation of Stat1 protein 1.963122e-4
GO:0009620 response to fungus 1.980010e-4
GO:0045582 positive regulation of T cell differentiation 2.001557e-4
GO:0010812 negative regulation of cell-substrate adhesion 2.032509e-4
GO:0044281 small molecule metabolic process 2.052862e-4
GO:0071577 zinc ion transmembrane transport 2.074160e-4
GO:0032321 positive regulation of Rho GTPase activity 2.102518e-4
GO:0003100 regulation of systemic arterial blood pressure by endothelin 2.148764e-4
GO:0071474 cellular hyperosmotic response 2.176223e-4
GO:0033239 negative regulation of cellular amine metabolic process 2.176223e-4
GO:0032780 negative regulation of ATPase activity 2.213252e-4
GO:0009226 nucleotide-sugar biosynthetic process 2.213252e-4
GO:0060603 mammary gland duct morphogenesis 2.222504e-4
GO:0045475 locomotor rhythm 2.231862e-4
GO:0021528 commissural neuron differentiation in spinal cord 2.231862e-4
GO:0032425 positive regulation of mismatch repair 2.252735e-4
GO:0006515 misfolded or incompletely synthesized protein catabolic process 2.278215e-4
GO:0021548 pons development 2.300946e-4
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 2.353226e-4
GO:0060179 male mating behavior 2.360478e-4
GO:0021754 facial nucleus development 2.390386e-4
GO:0003058 hormonal regulation of the force of heart contraction 2.390386e-4
GO:0032900 negative regulation of neurotrophin production 2.399979e-4
GO:0032244 positive regulation of nucleoside transport 2.399979e-4
GO:0043932 ossification involved in bone remodeling 2.427598e-4
GO:0007159 leukocyte cell-cell adhesion 2.508577e-4
GO:0051017 actin filament bundle assembly 2.547389e-4
GO:0044259 multicellular organismal macromolecule metabolic process 2.612746e-4
GO:0045838 positive regulation of membrane potential 2.717559e-4
GO:0048320 axial mesoderm formation 2.771342e-4
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 2.818035e-4
GO:0022604 regulation of cell morphogenesis 2.826339e-4
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 2.837806e-4
GO:0050862 positive regulation of T cell receptor signaling pathway 2.841068e-4
GO:0034224 cellular response to zinc ion starvation 2.884381e-4
GO:0061088 regulation of sequestering of zinc ion 2.919255e-4
GO:0010935 regulation of macrophage cytokine production 3.046600e-4
GO:0009991 response to extracellular stimulus 3.047145e-4
GO:0043587 tongue morphogenesis 3.059850e-4
GO:0030237 female sex determination 3.153617e-4
GO:0016056 rhodopsin mediated signaling pathway 3.153617e-4
GO:0043647 inositol phosphate metabolic process 3.165663e-4
GO:0046849 bone remodeling 3.208574e-4
GO:0042501 serine phosphorylation of STAT protein 3.264889e-4
GO:0032963 collagen metabolic process 3.314746e-4
GO:0060087 relaxation of vascular smooth muscle 3.350303e-4
GO:0051016 barbed-end actin filament capping 3.353100e-4
GO:0030520 estrogen receptor signaling pathway 3.414158e-4
GO:0007512 adult heart development 3.444114e-4
GO:0032656 regulation of interleukin-13 production 3.473049e-4
GO:0002682 regulation of immune system process 3.474584e-4
GO:0021612 facial nerve structural organization 3.488735e-4
GO:0035306 positive regulation of dephosphorylation 3.503287e-4
GO:0030853 negative regulation of granulocyte differentiation 3.535148e-4
GO:0006414 translational elongation 3.574302e-4
GO:2000145 regulation of cell motility 3.594016e-4
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 3.740358e-4
GO:0010536 positive regulation of activation of Janus kinase activity 3.740358e-4
GO:0060078 regulation of postsynaptic membrane potential 3.780914e-4
GO:0032674 regulation of interleukin-5 production 3.793510e-4
GO:0051005 negative regulation of lipoprotein lipase activity 3.844336e-4
GO:0051048 negative regulation of secretion 4.037834e-4
GO:0035967 cellular response to topologically incorrect protein 4.060345e-4
GO:0006955 immune response 4.065868e-4
GO:0051023 regulation of immunoglobulin secretion 4.075660e-4
GO:0015817 histidine transport 4.110647e-4
GO:0043268 positive regulation of potassium ion transport 4.142076e-4
GO:0018293 protein-FAD linkage 4.193494e-4
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 4.193494e-4
GO:0043588 skin development 4.221401e-4
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 4.223620e-4
GO:2000147 positive regulation of cell motility 4.319623e-4
GO:0070228 regulation of lymphocyte apoptosis 4.359300e-4
GO:0051444 negative regulation of ubiquitin-protein ligase activity 4.363756e-4
GO:0018993 somatic sex determination 4.393564e-4
GO:0042088 T-helper 1 type immune response 4.453488e-4
GO:0014909 smooth muscle cell migration 4.477506e-4
GO:0061370 testosterone biosynthetic process 4.545160e-4
GO:0050756 fractalkine metabolic process 4.545160e-4
GO:0033595 response to genistein 4.545160e-4
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 4.548542e-4
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development 4.596977e-4
GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity 4.596977e-4
GO:0007595 lactation 4.758115e-4
GO:0032355 response to estradiol stimulus 4.885704e-4
GO:0071899 negative regulation of estrogen receptor binding 5.016373e-4
GO:0050710 negative regulation of cytokine secretion 5.046906e-4
GO:0045416 positive regulation of interleukin-8 biosynthetic process 5.126278e-4
GO:0001909 leukocyte mediated cytotoxicity 5.198387e-4
GO:0061049 cell growth involved in cardiac muscle cell development 5.208906e-4
GO:0014873 response to muscle activity involved in regulation of muscle adaptation 5.208906e-4
GO:0003331 positive regulation of extracellular matrix constituent secretion 5.208906e-4
GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure 5.208906e-4
GO:0046148 pigment biosynthetic process 5.271778e-4
GO:0046632 alpha-beta T cell differentiation 5.337074e-4
GO:0043088 regulation of Cdc42 GTPase activity 5.371202e-4
GO:0048146 positive regulation of fibroblast proliferation 5.493104e-4
GO:0006754 ATP biosynthetic process 5.549256e-4
GO:0007096 regulation of exit from mitosis 5.632249e-4
GO:0034504 protein localization to nucleus 5.644698e-4
GO:0030335 positive regulation of cell migration 5.712868e-4
GO:0007260 tyrosine phosphorylation of STAT protein 5.715876e-4
GO:0010959 regulation of metal ion transport 5.731133e-4
GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein 5.768712e-4
GO:0019388 galactose catabolic process 5.768712e-4
GO:0010523 negative regulation of calcium ion transport into cytosol 5.802297e-4
GO:0045453 bone resorption 5.861685e-4
GO:0010873 positive regulation of cholesterol esterification 5.908042e-4
GO:0003099 positive regulation of the force of heart contraction by chemical signal 5.921890e-4
GO:0048386 positive regulation of retinoic acid receptor signaling pathway 6.092886e-4
GO:0060708 spongiotrophoblast differentiation 6.103237e-4
GO:0042592 homeostatic process 6.109341e-4
GO:0045065 cytotoxic T cell differentiation 6.221809e-4
GO:0021570 rhombomere 4 development 6.221809e-4
GO:0048339 paraxial mesoderm development 6.228119e-4
GO:0048147 negative regulation of fibroblast proliferation 6.354005e-4
GO:0030099 myeloid cell differentiation 6.361495e-4
GO:0006855 drug transmembrane transport 6.363467e-4
GO:0051891 positive regulation of cardioblast differentiation 6.512707e-4
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 6.540438e-4
GO:0045806 negative regulation of endocytosis 6.609155e-4
GO:0060033 anatomical structure regression 6.676972e-4
GO:0046415 urate metabolic process 6.676972e-4
GO:0009181 purine ribonucleoside diphosphate catabolic process 6.799806e-4
GO:0043400 cortisol secretion 6.802939e-4
GO:0031669 cellular response to nutrient levels 6.804426e-4
GO:0051461 positive regulation of corticotropin secretion 7.028378e-4
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 7.028378e-4
GO:0032696 negative regulation of interleukin-13 production 7.216329e-4
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process 7.370189e-4
GO:0072181 mesonephric duct formation 7.386028e-4
GO:0071733 transcriptional activation by promoter-enhancer looping 7.386028e-4
GO:0002438 acute inflammatory response to antigenic stimulus 7.386028e-4
GO:0010724 regulation of definitive erythrocyte differentiation 7.386028e-4
GO:0051873 killing by host of symbiont cells 7.410828e-4
GO:0032796 uropod organization 7.410828e-4
GO:0018963 phthalate metabolic process 7.410828e-4
GO:0050878 regulation of body fluid levels 7.534844e-4
GO:0007263 nitric oxide mediated signal transduction 7.591426e-4
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 7.678188e-4
GO:0060135 maternal process involved in female pregnancy 7.681458e-4
GO:0048871 multicellular organismal homeostasis 7.721096e-4
GO:0072376 protein activation cascade 7.769375e-4
GO:0006552 leucine catabolic process 7.774865e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0045940 positive regulation of steroid metabolic process 2.735468e-15
GO:0001957 intramembranous ossification 5.113595e-13
GO:0016064 immunoglobulin mediated immune response 1.448146e-12
GO:0070245 positive regulation of thymocyte apoptosis 2.375476e-12
GO:0019724 B cell mediated immunity 5.100873e-12
GO:0002449 lymphocyte mediated immunity 9.572203e-12
GO:0070234 positive regulation of T cell apoptosis 1.513278e-11
GO:0010873 positive regulation of cholesterol esterification 7.419960e-11
GO:0019218 regulation of steroid metabolic process 2.633143e-10
GO:0010872 regulation of cholesterol esterification 2.753603e-10
GO:0045834 positive regulation of lipid metabolic process 2.762419e-10
GO:0070208 protein heterotrimerization 3.083388e-10
GO:0033700 phospholipid efflux 4.016514e-10
GO:0044236 multicellular organismal metabolic process 4.224710e-10
GO:0002579 positive regulation of antigen processing and presentation 4.543222e-10
GO:0071417 cellular response to organic nitrogen 8.389771e-10
GO:0002443 leukocyte mediated immunity 8.433901e-10
GO:0070243 regulation of thymocyte apoptosis 8.836210e-10
GO:0016126 sterol biosynthetic process 2.186411e-9
GO:0060346 bone trabecula formation 3.261929e-9
GO:0071418 cellular response to amine stimulus 4.391875e-9
GO:0090023 positive regulation of neutrophil chemotaxis 5.283163e-9
GO:0070228 regulation of lymphocyte apoptosis 7.775800e-9
GO:0070232 regulation of T cell apoptosis 9.882451e-9
GO:0070230 positive regulation of lymphocyte apoptosis 1.437051e-8
GO:0031017 exocrine pancreas development 1.571925e-8
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.587090e-8
GO:0001516 prostaglandin biosynthetic process 2.134309e-8
GO:0007620 copulation 2.332556e-8
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.393451e-8
GO:0035691 macrophage migration inhibitory factor signaling pathway 3.524559e-8
GO:0009303 rRNA transcription 3.659404e-8
GO:0033085 negative regulation of T cell differentiation in thymus 4.777145e-8
GO:0006693 prostaglandin metabolic process 4.781020e-8
GO:0034505 tooth mineralization 5.046276e-8
GO:2000106 regulation of leukocyte apoptosis 5.590990e-8
GO:0019216 regulation of lipid metabolic process 5.932786e-8
GO:0071230 cellular response to amino acid stimulus 6.485899e-8
GO:0070508 cholesterol import 6.705885e-8
GO:0044259 multicellular organismal macromolecule metabolic process 7.050354e-8
GO:0010985 negative regulation of lipoprotein particle clearance 7.263502e-8
GO:0030818 negative regulation of cAMP biosynthetic process 7.681002e-8
GO:0032963 collagen metabolic process 8.089569e-8
GO:0014044 Schwann cell development 8.124312e-8
GO:0046890 regulation of lipid biosynthetic process 9.048341e-8
GO:0002577 regulation of antigen processing and presentation 9.479566e-8
GO:0046889 positive regulation of lipid biosynthetic process 1.332051e-7
GO:0046885 regulation of hormone biosynthetic process 1.419196e-7
GO:0015844 monoamine transport 1.678724e-7
GO:0050921 positive regulation of chemotaxis 1.742900e-7
GO:0006633 fatty acid biosynthetic process 1.790716e-7
GO:0071229 cellular response to acid 1.963043e-7
GO:0030595 leukocyte chemotaxis 1.963043e-7
GO:0034382 chylomicron remnant clearance 2.009503e-7
GO:0051004 regulation of lipoprotein lipase activity 2.480914e-7
GO:0045980 negative regulation of nucleotide metabolic process 2.692854e-7
GO:0046886 positive regulation of hormone biosynthetic process 2.697773e-7
GO:0002455 humoral immune response mediated by circulating immunoglobulin 2.850556e-7
GO:0019884 antigen processing and presentation of exogenous antigen 3.562043e-7
GO:0002478 antigen processing and presentation of exogenous peptide antigen 3.821588e-7
GO:0050900 leukocyte migration 4.391693e-7
GO:0033344 cholesterol efflux 4.581963e-7
GO:0070328 triglyceride homeostasis 5.126350e-7
GO:0050994 regulation of lipid catabolic process 5.646826e-7
GO:0010893 positive regulation of steroid biosynthetic process 5.825244e-7
GO:0031960 response to corticosteroid stimulus 6.301919e-7
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 6.714869e-7
GO:0010984 regulation of lipoprotein particle clearance 6.956739e-7
GO:0002250 adaptive immune response 6.972823e-7
GO:0070206 protein trimerization 7.533988e-7
GO:0002886 regulation of myeloid leukocyte mediated immunity 8.231640e-7
GO:0048545 response to steroid hormone stimulus 8.508437e-7
GO:0016125 sterol metabolic process 8.703901e-7
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 8.961309e-7
GO:0048771 tissue remodeling 9.023254e-7
GO:0006695 cholesterol biosynthetic process 9.180410e-7
GO:0051347 positive regulation of transferase activity 1.000027e-6
GO:0032103 positive regulation of response to external stimulus 1.068310e-6
GO:0071874 cellular response to norepinephrine stimulus 1.103195e-6
GO:0046456 icosanoid biosynthetic process 1.266283e-6
GO:0006952 defense response 1.328883e-6
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 1.453385e-6
GO:0043691 reverse cholesterol transport 1.613646e-6
GO:0090030 regulation of steroid hormone biosynthetic process 1.704508e-6
GO:0090022 regulation of neutrophil chemotaxis 1.922597e-6
GO:0010243 response to organic nitrogen 1.998503e-6
GO:0050920 regulation of chemotaxis 2.099867e-6
GO:0048148 behavioral response to cocaine 2.107030e-6
GO:0050713 negative regulation of interleukin-1 beta secretion 2.184115e-6
GO:0014037 Schwann cell differentiation 2.453513e-6
GO:0002821 positive regulation of adaptive immune response 2.483308e-6
GO:0060191 regulation of lipase activity 2.515973e-6
GO:0006636 unsaturated fatty acid biosynthetic process 2.616951e-6
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 2.651070e-6
GO:0006690 icosanoid metabolic process 2.994291e-6
GO:0090031 positive regulation of steroid hormone biosynthetic process 3.126590e-6
GO:0030865 cortical cytoskeleton organization 3.148268e-6
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 3.209052e-6
GO:0032352 positive regulation of hormone metabolic process 3.218372e-6
GO:0042304 regulation of fatty acid biosynthetic process 3.237273e-6
GO:0042415 norepinephrine metabolic process 3.268179e-6
GO:0046628 positive regulation of insulin receptor signaling pathway 3.380565e-6
GO:0000305 response to oxygen radical 3.486448e-6
GO:0019430 removal of superoxide radicals 3.504280e-6
GO:0014075 response to amine stimulus 3.548248e-6
GO:0002718 regulation of cytokine production involved in immune response 3.854152e-6
GO:0032964 collagen biosynthetic process 3.915407e-6
GO:0033081 regulation of T cell differentiation in thymus 4.002115e-6
GO:0033275 actin-myosin filament sliding 4.052700e-6
GO:0022011 myelination in peripheral nervous system 4.090380e-6
GO:0050995 negative regulation of lipid catabolic process 4.099619e-6
GO:2000108 positive regulation of leukocyte apoptosis 4.561853e-6
GO:0042149 cellular response to glucose starvation 4.652086e-6
GO:0006707 cholesterol catabolic process 5.072981e-6
GO:0033674 positive regulation of kinase activity 5.140178e-6
GO:0050810 regulation of steroid biosynthetic process 5.217455e-6
GO:0021782 glial cell development 5.218525e-6
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 5.339205e-6
GO:0050872 white fat cell differentiation 6.018154e-6
GO:0002642 positive regulation of immunoglobulin biosynthetic process 6.294479e-6
GO:0006694 steroid biosynthetic process 6.665031e-6
GO:0000303 response to superoxide 7.308633e-6
GO:0033505 floor plate morphogenesis 8.183418e-6
GO:0043031 negative regulation of macrophage activation 8.204654e-6
GO:0044243 multicellular organismal catabolic process 8.288519e-6
GO:0032488 Cdc42 protein signal transduction 8.540489e-6
GO:0045860 positive regulation of protein kinase activity 8.779099e-6
GO:0061001 regulation of dendritic spine morphogenesis 8.937152e-6
GO:0032094 response to food 9.094424e-6
GO:0051005 negative regulation of lipoprotein lipase activity 1.025497e-5
GO:0043085 positive regulation of catalytic activity 1.054121e-5
GO:0006833 water transport 1.128313e-5
GO:0060343 trabecula formation 1.146278e-5
GO:0061077 chaperone-mediated protein folding 1.215009e-5
GO:0072376 protein activation cascade 1.268147e-5
GO:0015850 organic alcohol transport 1.268401e-5
GO:0051937 catecholamine transport 1.331316e-5
GO:0045907 positive regulation of vasoconstriction 1.334981e-5
GO:0007493 endodermal cell fate determination 1.369890e-5
GO:0010765 positive regulation of sodium ion transport 1.373907e-5
GO:0070252 actin-mediated cell contraction 1.417481e-5
GO:0050865 regulation of cell activation 1.435923e-5
GO:0044341 sodium-dependent phosphate transport 1.441550e-5
GO:0090342 regulation of cell aging 1.488649e-5
GO:0043300 regulation of leukocyte degranulation 1.622600e-5
GO:0007320 insemination 1.686732e-5
GO:0001974 blood vessel remodeling 1.744403e-5
GO:0002251 organ or tissue specific immune response 1.746465e-5
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 1.802397e-5
GO:0007614 short-term memory 1.860368e-5
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 1.864325e-5
GO:0009628 response to abiotic stimulus 1.878455e-5
GO:0008203 cholesterol metabolic process 1.975306e-5
GO:0045581 negative regulation of T cell differentiation 2.027664e-5
GO:0007522 visceral muscle development 2.078473e-5
GO:0032369 negative regulation of lipid transport 2.161221e-5
GO:0002385 mucosal immune response 2.172459e-5
GO:0002252 immune effector process 2.318026e-5
GO:0070741 response to interleukin-6 2.381848e-5
GO:0002690 positive regulation of leukocyte chemotaxis 2.467289e-5
GO:0008211 glucocorticoid metabolic process 2.523283e-5
GO:0045760 positive regulation of action potential 2.689188e-5
GO:0035307 positive regulation of protein dephosphorylation 2.701961e-5
GO:0032374 regulation of cholesterol transport 2.783580e-5
GO:0002694 regulation of leukocyte activation 2.821033e-5
GO:0050432 catecholamine secretion 3.005844e-5
GO:0031424 keratinization 3.053358e-5
GO:0042487 regulation of odontogenesis of dentine-containing tooth 3.115074e-5
GO:0044240 multicellular organismal lipid catabolic process 3.244991e-5
GO:0002344 B cell affinity maturation 3.333487e-5
GO:0001985 negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 3.411262e-5
GO:0046394 carboxylic acid biosynthetic process 3.490613e-5
GO:0006956 complement activation 3.684219e-5
GO:0035306 positive regulation of dephosphorylation 3.811832e-5
GO:0030049 muscle filament sliding 4.029900e-5
GO:0050706 regulation of interleukin-1 beta secretion 4.079308e-5
GO:0090343 positive regulation of cell aging 4.177189e-5
GO:0045725 positive regulation of glycogen biosynthetic process 4.294859e-5
GO:0008340 determination of adult lifespan 4.437961e-5
GO:0060192 negative regulation of lipase activity 4.461806e-5
GO:0045087 innate immune response 4.587758e-5
GO:0009719 response to endogenous stimulus 4.868140e-5
GO:0030199 collagen fibril organization 4.897780e-5
GO:0051085 chaperone mediated protein folding requiring cofactor 4.974295e-5
GO:0002906 negative regulation of mature B cell apoptosis 5.304953e-5
GO:0016925 protein sumoylation 5.586551e-5
GO:0048242 epinephrine secretion 5.593238e-5
GO:0007422 peripheral nervous system development 5.600355e-5
GO:0032350 regulation of hormone metabolic process 5.814618e-5
GO:0043200 response to amino acid stimulus 5.817345e-5
GO:0032375 negative regulation of cholesterol transport 6.051230e-5
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 6.051230e-5
GO:0046847 filopodium assembly 6.212925e-5
GO:0015724 formate transport 6.313509e-5
GO:0002442 serotonin secretion involved in inflammatory response 6.320079e-5
GO:0006378 mRNA polyadenylation 6.431067e-5
GO:0002673 regulation of acute inflammatory response 6.504378e-5
GO:0048739 cardiac muscle fiber development 6.538569e-5
GO:0010741 negative regulation of intracellular protein kinase cascade 6.565759e-5
GO:0043535 regulation of blood vessel endothelial cell migration 6.633373e-5
GO:0002740 negative regulation of cytokine secretion involved in immune response 6.839721e-5
GO:0035249 synaptic transmission, glutamatergic 6.928053e-5
GO:0006954 inflammatory response 6.983733e-5
GO:0050711 negative regulation of interleukin-1 secretion 7.231952e-5
GO:0042104 positive regulation of activated T cell proliferation 7.595210e-5
GO:0019217 regulation of fatty acid metabolic process 7.660814e-5
GO:0001935 endothelial cell proliferation 8.338305e-5
GO:0010906 regulation of glucose metabolic process 8.358078e-5
GO:0010565 regulation of cellular ketone metabolic process 8.364762e-5
GO:0002688 regulation of leukocyte chemotaxis 8.384015e-5
GO:0006958 complement activation, classical pathway 8.427515e-5
GO:0033003 regulation of mast cell activation 8.520214e-5
GO:2000772 regulation of cellular senescence 8.560522e-5
GO:0002604 regulation of dendritic cell antigen processing and presentation 9.045849e-5
GO:0030035 microspike assembly 9.196900e-5
GO:0050790 regulation of catalytic activity 9.366737e-5
GO:0045937 positive regulation of phosphate metabolic process 9.499492e-5
GO:0008610 lipid biosynthetic process 9.874702e-5
GO:0051338 regulation of transferase activity 1.024037e-4
GO:0070875 positive regulation of glycogen metabolic process 1.029566e-4
GO:0043503 skeletal muscle fiber adaptation 1.037412e-4
GO:0001826 inner cell mass cell differentiation 1.037412e-4
GO:0007512 adult heart development 1.076770e-4
GO:0048644 muscle organ morphogenesis 1.095079e-4
GO:0010900 negative regulation of phosphatidylcholine catabolic process 1.102891e-4
GO:0055009 atrial cardiac muscle tissue morphogenesis 1.105142e-4
GO:0044093 positive regulation of molecular function 1.108031e-4
GO:0031440 regulation of mRNA 3'-end processing 1.108119e-4
GO:0045922 negative regulation of fatty acid metabolic process 1.157646e-4
GO:0017157 regulation of exocytosis 1.184118e-4
GO:0043549 regulation of kinase activity 1.196899e-4
GO:0071495 cellular response to endogenous stimulus 1.222780e-4
GO:0042044 fluid transport 1.250668e-4
GO:0014738 regulation of muscle hyperplasia 1.259470e-4
GO:0005979 regulation of glycogen biosynthetic process 1.266474e-4
GO:0045859 regulation of protein kinase activity 1.275695e-4
GO:0002697 regulation of immune effector process 1.311077e-4
GO:0045620 negative regulation of lymphocyte differentiation 1.328718e-4
GO:0007418 ventral midline development 1.377456e-4
GO:0002115 store-operated calcium entry 1.394758e-4
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 1.402627e-4
GO:0060696 regulation of phospholipid catabolic process 1.402946e-4
GO:0001817 regulation of cytokine production 1.461381e-4
GO:0002883 regulation of hypersensitivity 1.491547e-4
GO:0018149 peptide cross-linking 1.495998e-4
GO:0006547 histidine metabolic process 1.544757e-4
GO:0030301 cholesterol transport 1.557485e-4
GO:0002827 positive regulation of T-helper 1 type immune response 1.579389e-4
GO:0043067 regulation of programmed cell death 1.588470e-4
GO:0002554 serotonin secretion by platelet 1.635255e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.657584e-4
GO:0050863 regulation of T cell activation 1.671871e-4
GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 1.693944e-4
GO:0034369 plasma lipoprotein particle remodeling 1.704348e-4
GO:0051345 positive regulation of hydrolase activity 1.761282e-4
GO:0044255 cellular lipid metabolic process 1.763709e-4
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1.767126e-4
GO:0050778 positive regulation of immune response 1.786524e-4
GO:0050704 regulation of interleukin-1 secretion 1.807757e-4
GO:0043467 regulation of generation of precursor metabolites and energy 1.825744e-4
GO:0006066 alcohol metabolic process 1.828730e-4
GO:0060299 negative regulation of sarcomere organization 1.848997e-4
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 1.848997e-4
GO:0042703 menstruation 1.848997e-4
GO:0019101 female somatic sex determination 1.848997e-4
GO:0031442 positive regulation of mRNA 3'-end processing 1.896075e-4
GO:0006669 sphinganine-1-phosphate biosynthetic process 1.943694e-4
GO:0002687 positive regulation of leukocyte migration 1.973257e-4
GO:0043462 regulation of ATPase activity 1.990002e-4
GO:0006826 iron ion transport 2.003028e-4
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 2.038550e-4
GO:0009991 response to extracellular stimulus 2.050978e-4
GO:0051384 response to glucocorticoid stimulus 2.087131e-4
GO:0002739 regulation of cytokine secretion involved in immune response 2.095091e-4
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.221750e-4
GO:0070873 regulation of glycogen metabolic process 2.252104e-4
GO:0055088 lipid homeostasis 2.264130e-4
GO:0033136 serine phosphorylation of STAT3 protein 2.274065e-4
GO:0021508 floor plate formation 2.274065e-4
GO:0042981 regulation of apoptosis 2.286831e-4
GO:0061383 trabecula morphogenesis 2.315539e-4
GO:0015914 phospholipid transport 2.382047e-4
GO:0071827 plasma lipoprotein particle organization 2.449742e-4
GO:0048935 peripheral nervous system neuron development 2.486578e-4
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 2.492810e-4
GO:0033504 floor plate development 2.562703e-4
GO:0050776 regulation of immune response 2.631873e-4
GO:0002440 production of molecular mediator of immune response 2.667571e-4
GO:0006706 steroid catabolic process 2.710909e-4
GO:0002576 platelet degranulation 2.713769e-4
GO:0010987 negative regulation of high-density lipoprotein particle clearance 2.750965e-4
GO:0010897 negative regulation of triglyceride catabolic process 2.750965e-4
GO:0015684 ferrous iron transport 2.804267e-4
GO:0010288 response to lead ion 2.825321e-4
GO:0002903 negative regulation of B cell apoptosis 2.825321e-4
GO:0006548 histidine catabolic process 2.899779e-4
GO:0032516 positive regulation of phosphoprotein phosphatase activity 2.901070e-4
GO:0002027 regulation of heart rate 2.919927e-4
GO:0002885 positive regulation of hypersensitivity 2.929098e-4
GO:0045723 positive regulation of fatty acid biosynthetic process 2.944116e-4
GO:0051084 'de novo' posttranslational protein folding 2.945583e-4
GO:0006629 lipid metabolic process 3.087388e-4
GO:0010896 regulation of triglyceride catabolic process 3.091037e-4
GO:0070887 cellular response to chemical stimulus 3.093130e-4
GO:0071732 cellular response to nitric oxide 3.136907e-4
GO:0009725 response to hormone stimulus 3.226463e-4
GO:0046006 regulation of activated T cell proliferation 3.231779e-4
GO:0060627 regulation of vesicle-mediated transport 3.232210e-4
GO:0006941 striated muscle contraction 3.232580e-4
GO:0001932 regulation of protein phosphorylation 3.331919e-4
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 3.339811e-4
GO:0019220 regulation of phosphate metabolic process 3.428358e-4
GO:0042632 cholesterol homeostasis 3.496457e-4
GO:0002700 regulation of production of molecular mediator of immune response 3.540998e-4
GO:0051291 protein heterooligomerization 3.595334e-4
GO:0015837 amine transport 3.632302e-4
GO:0050651 dermatan sulfate proteoglycan biosynthetic process 3.686873e-4
GO:0009103 lipopolysaccharide biosynthetic process 3.720282e-4
GO:0048241 epinephrine transport 3.955505e-4
GO:0033131 regulation of glucokinase activity 3.975684e-4
GO:0051591 response to cAMP 4.019198e-4
GO:0031016 pancreas development 4.127616e-4
GO:0030300 regulation of intestinal cholesterol absorption 4.185555e-4
GO:0010907 positive regulation of glucose metabolic process 4.198303e-4
GO:0045740 positive regulation of DNA replication 4.226363e-4
GO:0071731 response to nitric oxide 4.311375e-4
GO:0042137 sequestering of neurotransmitter 4.373335e-4
GO:0042661 regulation of mesodermal cell fate specification 4.411715e-4
GO:0001101 response to acid 4.437437e-4
GO:0090201 negative regulation of release of cytochrome c from mitochondria 4.462252e-4
GO:0042325 regulation of phosphorylation 4.776740e-4
GO:0030240 skeletal muscle thin filament assembly 4.824856e-4
GO:0030866 cortical actin cytoskeleton organization 4.891904e-4
GO:0000105 histidine biosynthetic process 5.053492e-4
GO:0010936 negative regulation of macrophage cytokine production 5.132775e-4
GO:0002026 regulation of the force of heart contraction 5.271399e-4
GO:0032733 positive regulation of interleukin-10 production 5.295234e-4
GO:0016310 phosphorylation 5.589741e-4
GO:0046069 cGMP catabolic process 5.594763e-4
GO:0065009 regulation of molecular function 5.662329e-4
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 5.681561e-4
GO:0050795 regulation of behavior 5.940435e-4
GO:0006109 regulation of carbohydrate metabolic process 6.058080e-4
GO:0032287 peripheral nervous system myelin maintenance 6.149451e-4
GO:0031399 regulation of protein modification process 6.172115e-4
GO:0009134 nucleoside diphosphate catabolic process 6.212721e-4
GO:0008366 axon ensheathment 6.216517e-4
GO:0002377 immunoglobulin production 6.406455e-4
GO:0032912 negative regulation of transforming growth factor beta2 production 6.698679e-4
GO:0034435 cholesterol esterification 6.965038e-4
GO:0040017 positive regulation of locomotion 7.280910e-4
GO:0034380 high-density lipoprotein particle assembly 7.345886e-4
GO:0050685 positive regulation of mRNA processing 7.573664e-4
GO:0070665 positive regulation of leukocyte proliferation 7.620792e-4
GO:0016338 calcium-independent cell-cell adhesion 7.766561e-4
GO:0032878 regulation of establishment or maintenance of cell polarity 7.809442e-4
GO:0002407 dendritic cell chemotaxis 7.876490e-4
GO:0022010 central nervous system myelination 7.881147e-4
GO:0071702 organic substance transport 7.886421e-4
GO:0021936 regulation of cerebellar granule cell precursor proliferation 7.994723e-4
GO:0007009 plasma membrane organization 8.006938e-4
GO:0055072 iron ion homeostasis 8.141989e-4
GO:0097035 regulation of membrane lipid distribution 8.157757e-4
GO:0014049 positive regulation of glutamate secretion 8.256757e-4
GO:0010675 regulation of cellular carbohydrate metabolic process 8.382831e-4
GO:0043084 penile erection 8.492896e-4
GO:0042501 serine phosphorylation of STAT protein 8.492896e-4
GO:0010812 negative regulation of cell-substrate adhesion 8.505219e-4
GO:0051272 positive regulation of cellular component movement 8.678040e-4
GO:0015749 monosaccharide transport 8.925689e-4
GO:0021819 layer formation in cerebral cortex 8.947420e-4
GO:2000107 negative regulation of leukocyte apoptosis 9.010299e-4
GO:0042327 positive regulation of phosphorylation 9.013107e-4
GO:0050871 positive regulation of B cell activation 9.034465e-4
GO:0071622 regulation of granulocyte chemotaxis 9.068707e-4
GO:0010614 negative regulation of cardiac muscle hypertrophy 9.077003e-4
GO:0006760 folic acid-containing compound metabolic process 9.102553e-4
GO:0070305 response to cGMP 9.114654e-4
GO:0035264 multicellular organism growth 9.344540e-4
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 9.589911e-4
GO:0060326 cell chemotaxis 9.648011e-4
GO:0042552 myelination 9.666680e-4
GO:0001934 positive regulation of protein phosphorylation 9.694045e-4
GO:0051182 coenzyme transport 9.727091e-4
GO:2000178 negative regulation of neural precursor cell proliferation 9.828588e-4
GO:0006796 phosphate-containing compound metabolic process 9.828768e-4
GO:0006360 transcription from RNA polymerase I promoter 9.859234e-4
GO:0032368 regulation of lipid transport 9.973567e-4
GO:0043304 regulation of mast cell degranulation 9.978218e-4
GO:0032946 positive regulation of mononuclear cell proliferation 1.007072e-3
GO:0060415 muscle tissue morphogenesis 1.007168e-3
GO:0015791 polyol transport 1.009494e-3
GO:0001819 positive regulation of cytokine production 1.012737e-3
GO:0000492 box C/D snoRNP assembly 1.013972e-3
GO:0032530 regulation of microvillus organization 1.031028e-3
GO:0002074 extraocular skeletal muscle development 1.031028e-3
GO:0006487 protein N-linked glycosylation 1.054467e-3
GO:0043405 regulation of MAP kinase activity 1.064580e-3
GO:0002830 positive regulation of type 2 immune response 1.076614e-3
GO:0001820 serotonin secretion 1.076614e-3
GO:0031427 response to methotrexate 1.083767e-3
GO:0043217 myelin maintenance 1.104417e-3
GO:0002685 regulation of leukocyte migration 1.104498e-3
GO:0030239 myofibril assembly 1.110463e-3
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.116001e-3
GO:0060620 regulation of cholesterol import 1.122081e-3
GO:0045717 negative regulation of fatty acid biosynthetic process 1.124243e-3
GO:0030593 neutrophil chemotaxis 1.126779e-3
GO:0072539 T-helper 17 cell differentiation 1.153882e-3
GO:0006545 glycine biosynthetic process 1.153882e-3
GO:0015876 acetyl-CoA transport 1.159017e-3
GO:0031579 membrane raft organization 1.161948e-3
GO:0010823 negative regulation of mitochondrion organization 1.161948e-3
GO:0043525 positive regulation of neuron apoptosis 1.164030e-3
GO:0071705 nitrogen compound transport 1.167967e-3
GO:0071593 lymphocyte aggregation 1.168725e-3
GO:0006668 sphinganine-1-phosphate metabolic process 1.168725e-3
GO:0010989 negative regulation of low-density lipoprotein particle clearance 1.189130e-3
GO:0060426 lung vasculature development 1.190505e-3
GO:0051249 regulation of lymphocyte activation 1.199899e-3
GO:0007586 digestion 1.200089e-3
GO:2001021 negative regulation of response to DNA damage stimulus 1.225558e-3
GO:0030826 regulation of cGMP biosynthetic process 1.235910e-3
GO:0035304 regulation of protein dephosphorylation 1.237832e-3
GO:0051270 regulation of cellular component movement 1.239858e-3
GO:0042711 maternal behavior 1.246430e-3
GO:0045103 intermediate filament-based process 1.285278e-3
GO:0050710 negative regulation of cytokine secretion 1.285641e-3
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.288881e-3
GO:0015920 lipopolysaccharide transport 1.302113e-3
GO:0010982 regulation of high-density lipoprotein particle clearance 1.302113e-3
GO:0045840 positive regulation of mitosis 1.314085e-3
GO:0007517 muscle organ development 1.332689e-3
GO:0006631 fatty acid metabolic process 1.348242e-3
GO:0044283 small molecule biosynthetic process 1.350269e-3
GO:0055010 ventricular cardiac muscle tissue morphogenesis 1.361781e-3
GO:0031032 actomyosin structure organization 1.375535e-3
GO:0060621 negative regulation of cholesterol import 1.383543e-3
GO:0060052 neurofilament cytoskeleton organization 1.389008e-3
GO:0031295 T cell costimulation 1.389699e-3
GO:0010259 multicellular organismal aging 1.405418e-3
GO:0071299 cellular response to vitamin A 1.424070e-3
GO:0009416 response to light stimulus 1.434073e-3
GO:0002684 positive regulation of immune system process 1.463680e-3
GO:0006959 humoral immune response 1.499442e-3
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 1.500245e-3
GO:0042136 neurotransmitter biosynthetic process 1.500245e-3
GO:0002426 immunoglobulin production in mucosal tissue 1.500245e-3
GO:0006879 cellular iron ion homeostasis 1.509726e-3
GO:0002376 immune system process 1.512771e-3
GO:0009100 glycoprotein metabolic process 1.533004e-3
GO:0071385 cellular response to glucocorticoid stimulus 1.535067e-3
GO:0007618 mating 1.545733e-3
GO:0043270 positive regulation of ion transport 1.562210e-3
GO:0048261 negative regulation of receptor-mediated endocytosis 1.570720e-3
GO:0046604 positive regulation of mitotic centrosome separation 1.585789e-3
GO:0043252 sodium-independent organic anion transport 1.585789e-3
GO:0002561 basophil degranulation 1.585789e-3
GO:0032532 regulation of microvillus length 1.585789e-3
GO:0031124 mRNA 3'-end processing 1.596613e-3
GO:0003229 ventricular cardiac muscle tissue development 1.631145e-3
GO:0007602 phototransduction 1.646771e-3
GO:2000189 positive regulation of cholesterol homeostasis 1.669470e-3
GO:0050861 positive regulation of B cell receptor signaling pathway 1.669470e-3
GO:0048320 axial mesoderm formation 1.669470e-3
GO:0050671 positive regulation of lymphocyte proliferation 1.671250e-3
GO:0032515 negative regulation of phosphoprotein phosphatase activity 1.674968e-3
GO:0046655 folic acid metabolic process 1.679527e-3
GO:0008016 regulation of heart contraction 1.699944e-3
GO:0051336 regulation of hydrolase activity 1.717496e-3
GO:0035094 response to nicotine 1.719516e-3
GO:0048520 positive regulation of behavior 1.728041e-3
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine 1.734682e-3
GO:0010935 regulation of macrophage cytokine production 1.734682e-3
GO:0045924 regulation of female receptivity 1.746501e-3
GO:0060351 cartilage development involved in endochondral bone morphogenesis 1.794052e-3
GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 1.794052e-3
GO:0043589 skin morphogenesis 1.810700e-3
GO:0006641 triglyceride metabolic process 1.812845e-3
GO:0008645 hexose transport 1.814278e-3
GO:2000147 positive regulation of cell motility 1.824085e-3
GO:2000273 positive regulation of receptor activity 1.843714e-3
GO:0010976 positive regulation of neuron projection development 1.866851e-3
GO:0010941 regulation of cell death 1.871033e-3
GO:2000465 regulation of glycogen (starch) synthase activity 1.902771e-3
GO:0071383 cellular response to steroid hormone stimulus 1.919016e-3
GO:0071453 cellular response to oxygen levels 1.943281e-3
GO:2000412 positive regulation of thymocyte migration 1.947963e-3
GO:0031998 regulation of fatty acid beta-oxidation 1.954401e-3
GO:0014051 gamma-aminobutyric acid secretion 1.960486e-3
GO:0010460 positive regulation of heart rate 1.983240e-3
GO:0006013 mannose metabolic process 1.999132e-3
GO:0071300 cellular response to retinoic acid 2.030868e-3
GO:0002125 maternal aggressive behavior 2.032280e-3
GO:0060709 glycogen cell development involved in embryonic placenta development 2.032280e-3
GO:0072011 glomerular endothelium development 2.032280e-3
GO:0018993 somatic sex determination 2.032280e-3
GO:0031214 biomineral tissue development 2.050324e-3
GO:0043502 regulation of muscle adaptation 2.054010e-3
GO:0006555 methionine metabolic process 2.077714e-3