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Novel motif:63

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name:motif63_GTNCCA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0046655 folic acid metabolic process 4.647283e-10
GO:0010891 negative regulation of sequestering of triglyceride 1.491502e-9
GO:0015705 iodide transport 6.120519e-9
GO:0045820 negative regulation of glycolysis 1.537799e-8
GO:0043249 erythrocyte maturation 1.661584e-8
GO:0003009 skeletal muscle contraction 1.910765e-8
GO:0051241 negative regulation of multicellular organismal process 2.017385e-8
GO:0051412 response to corticosterone stimulus 2.309338e-8
GO:0007585 respiratory gaseous exchange 2.522161e-8
GO:0006544 glycine metabolic process 3.115249e-8
GO:0009142 nucleoside triphosphate biosynthetic process 3.914456e-8
GO:0009201 ribonucleoside triphosphate biosynthetic process 4.192059e-8
GO:2000119 negative regulation of sodium-dependent phosphate transport 4.682865e-8
GO:0006449 regulation of translational termination 5.644451e-8
GO:0003016 respiratory system process 5.775123e-8
GO:0009145 purine nucleoside triphosphate biosynthetic process 6.485054e-8
GO:0060535 trachea cartilage morphogenesis 7.287085e-8
GO:0060669 embryonic placenta morphogenesis 7.524484e-8
GO:0006575 cellular modified amino acid metabolic process 7.781067e-8
GO:0060749 mammary gland alveolus development 8.130647e-8
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 8.552175e-8
GO:0032312 regulation of ARF GTPase activity 1.126553e-7
GO:0007165 signal transduction 1.391611e-7
GO:0050881 musculoskeletal movement 1.540223e-7
GO:2000249 regulation of actin cytoskeleton reorganization 1.917627e-7
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 2.125935e-7
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 2.125935e-7
GO:0051716 cellular response to stimulus 2.366565e-7
GO:0033599 regulation of mammary gland epithelial cell proliferation 2.475580e-7
GO:0046939 nucleotide phosphorylation 2.891255e-7
GO:0051385 response to mineralocorticoid stimulus 2.899901e-7
GO:0046131 pyrimidine ribonucleoside metabolic process 3.541017e-7
GO:0060482 lobar bronchus development 5.005591e-7
GO:0009629 response to gravity 6.083802e-7
GO:0006304 DNA modification 1.084551e-6
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 1.113514e-6
GO:0031330 negative regulation of cellular catabolic process 1.139902e-6
GO:0009071 serine family amino acid catabolic process 1.207045e-6
GO:0006695 cholesterol biosynthetic process 1.334047e-6
GO:0007568 aging 1.517336e-6
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine 1.556578e-6
GO:0044281 small molecule metabolic process 1.579422e-6
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 1.682002e-6
GO:0006754 ATP biosynthetic process 1.682060e-6
GO:0006760 folic acid-containing compound metabolic process 2.008680e-6
GO:0060534 trachea cartilage development 2.049976e-6
GO:0060706 cell differentiation involved in embryonic placenta development 2.160088e-6
GO:0006213 pyrimidine nucleoside metabolic process 2.272584e-6
GO:0010889 regulation of sequestering of triglyceride 2.387859e-6
GO:0051001 negative regulation of nitric-oxide synthase activity 2.443691e-6
GO:0030277 maintenance of gastrointestinal epithelium 2.573680e-6
GO:0008215 spermine metabolic process 3.037449e-6
GO:0001974 blood vessel remodeling 3.047252e-6
GO:0060764 cell-cell signaling involved in mammary gland development 3.184120e-6
GO:0048144 fibroblast proliferation 3.426544e-6
GO:0045056 transcytosis 3.470385e-6
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 3.582778e-6
GO:0016126 sterol biosynthetic process 3.624737e-6
GO:0034340 response to type I interferon 3.758095e-6
GO:0035556 intracellular signal transduction 4.538975e-6
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 4.560195e-6
GO:0006982 response to lipid hydroperoxide 4.851808e-6
GO:0006820 anion transport 5.288589e-6
GO:0015698 inorganic anion transport 5.564004e-6
GO:0060337 type I interferon-mediated signaling pathway 6.140621e-6
GO:0019388 galactose catabolic process 6.354155e-6
GO:0002069 columnar/cuboidal epithelial cell maturation 6.536762e-6
GO:0030195 negative regulation of blood coagulation 6.571694e-6
GO:0006546 glycine catabolic process 6.652125e-6
GO:0002238 response to molecule of fungal origin 6.730650e-6
GO:0010288 response to lead ion 6.775922e-6
GO:0044275 cellular carbohydrate catabolic process 7.569650e-6
GO:0046208 spermine catabolic process 7.728913e-6
GO:0016052 carbohydrate catabolic process 7.830774e-6
GO:0006955 immune response 8.188092e-6
GO:0060708 spongiotrophoblast differentiation 8.431392e-6
GO:0006720 isoprenoid metabolic process 8.724797e-6
GO:0046365 monosaccharide catabolic process 9.239685e-6
GO:0032526 response to retinoic acid 9.479356e-6
GO:0009069 serine family amino acid metabolic process 9.557874e-6
GO:0060707 trophoblast giant cell differentiation 9.804061e-6
GO:0006621 protein retention in ER lumen 1.027659e-5
GO:0008299 isoprenoid biosynthetic process 1.127677e-5
GO:0072061 inner medullary collecting duct development 1.199551e-5
GO:0072060 outer medullary collecting duct development 1.199551e-5
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 1.199551e-5
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 1.213678e-5
GO:0032203 telomere formation via telomerase 1.233744e-5
GO:0048631 regulation of skeletal muscle tissue growth 1.291485e-5
GO:0050902 leukocyte adhesive activation 1.308674e-5
GO:0051041 positive regulation of calcium-independent cell-cell adhesion 1.308674e-5
GO:0006220 pyrimidine nucleotide metabolic process 1.340511e-5
GO:0042403 thyroid hormone metabolic process 1.426182e-5
GO:0032689 negative regulation of interferon-gamma production 1.441501e-5
GO:0030641 regulation of cellular pH 1.525230e-5
GO:0045606 positive regulation of epidermal cell differentiation 1.558972e-5
GO:0072527 pyrimidine-containing compound metabolic process 1.584104e-5
GO:0051453 regulation of intracellular pH 1.607359e-5
GO:0030225 macrophage differentiation 1.637280e-5
GO:0006885 regulation of pH 1.651216e-5
GO:0051452 intracellular pH reduction 1.676251e-5
GO:0046135 pyrimidine nucleoside catabolic process 1.768994e-5
GO:0045123 cellular extravasation 1.821068e-5
GO:0048771 tissue remodeling 1.842875e-5
GO:0042908 xenobiotic transport 1.940119e-5
GO:0023052 signaling 1.947717e-5
GO:0072528 pyrimidine-containing compound biosynthetic process 1.967411e-5
GO:0009116 nucleoside metabolic process 1.993555e-5
GO:0043542 endothelial cell migration 2.006618e-5
GO:0019320 hexose catabolic process 2.042277e-5
GO:0032796 uropod organization 2.150416e-5
GO:0006826 iron ion transport 2.260611e-5
GO:0031960 response to corticosteroid stimulus 2.288156e-5
GO:0043320 natural killer cell degranulation 2.319650e-5
GO:0006520 cellular amino acid metabolic process 2.346979e-5
GO:0032414 positive regulation of ion transmembrane transporter activity 2.527881e-5
GO:0034097 response to cytokine stimulus 2.571169e-5
GO:0070885 negative regulation of calcineurin-NFAT signaling pathway 2.593252e-5
GO:0032202 telomere assembly 2.597044e-5
GO:0009298 GDP-mannose biosynthetic process 2.618671e-5
GO:0018094 protein polyglycylation 2.625439e-5
GO:0045604 regulation of epidermal cell differentiation 2.948007e-5
GO:0009268 response to pH 2.965769e-5
GO:0045851 pH reduction 3.006168e-5
GO:0042398 cellular modified amino acid biosynthetic process 3.084245e-5
GO:0060574 intestinal epithelial cell maturation 3.175529e-5
GO:0009308 amine metabolic process 3.188754e-5
GO:0030719 P granule organization 3.362108e-5
GO:0006810 transport 3.445400e-5
GO:0009199 ribonucleoside triphosphate metabolic process 3.623057e-5
GO:0051248 negative regulation of protein metabolic process 3.742603e-5
GO:0006066 alcohol metabolic process 3.869969e-5
GO:0012502 induction of programmed cell death 3.935948e-5
GO:0006694 steroid biosynthetic process 4.049105e-5
GO:0003059 positive regulation of the force of heart contraction by epinephrine 4.124777e-5
GO:0043243 positive regulation of protein complex disassembly 4.183483e-5
GO:0002920 regulation of humoral immune response 4.211533e-5
GO:0048246 macrophage chemotaxis 4.286750e-5
GO:0051384 response to glucocorticoid stimulus 4.465616e-5
GO:0015893 drug transport 4.492495e-5
GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity 4.551903e-5
GO:0009205 purine ribonucleoside triphosphate metabolic process 4.625886e-5
GO:0071347 cellular response to interleukin-1 4.765048e-5
GO:0051289 protein homotetramerization 4.765048e-5
GO:0030198 extracellular matrix organization 4.859912e-5
GO:0009119 ribonucleoside metabolic process 4.890129e-5
GO:0021754 facial nucleus development 4.927583e-5
GO:0010631 epithelial cell migration 4.958835e-5
GO:0051234 establishment of localization 5.042381e-5
GO:0001977 renal system process involved in regulation of blood volume 5.081878e-5
GO:0060711 labyrinthine layer development 5.143362e-5
GO:0006821 chloride transport 5.192132e-5
GO:0009144 purine nucleoside triphosphate metabolic process 5.232962e-5
GO:0006917 induction of apoptosis 5.245925e-5
GO:0060056 mammary gland involution 5.579178e-5
GO:0007028 cytoplasm organization 5.626114e-5
GO:0035811 negative regulation of urine volume 5.640340e-5
GO:0050896 response to stimulus 5.656005e-5
GO:0009698 phenylpropanoid metabolic process 6.030516e-5
GO:0032269 negative regulation of cellular protein metabolic process 6.231490e-5
GO:0050909 sensory perception of taste 6.288705e-5
GO:0030878 thyroid gland development 6.294151e-5
GO:0042446 hormone biosynthetic process 6.325796e-5
GO:0032012 regulation of ARF protein signal transduction 6.555901e-5
GO:0060712 spongiotrophoblast layer development 6.733908e-5
GO:0060670 branching involved in embryonic placenta morphogenesis 6.832823e-5
GO:0000093 mitotic telophase 6.850888e-5
GO:0009628 response to abiotic stimulus 6.889308e-5
GO:0018293 protein-FAD linkage 6.994383e-5
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 6.994383e-5
GO:0002502 peptide antigen assembly with MHC class I protein complex 6.994383e-5
GO:0072110 glomerular mesangial cell proliferation 7.196203e-5
GO:0007154 cell communication 7.245305e-5
GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter 7.293092e-5
GO:0031442 positive regulation of mRNA 3'-end processing 7.458694e-5
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 7.925076e-5
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 7.925076e-5
GO:0045947 negative regulation of translational initiation 7.952733e-5
GO:0006446 regulation of translational initiation 8.053219e-5
GO:0032793 positive regulation of CREB transcription factor activity 8.142137e-5
GO:0046474 glycerophospholipid biosynthetic process 8.232427e-5
GO:0015684 ferrous iron transport 8.667661e-5
GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure 8.861599e-5
GO:0006096 glycolysis 8.931102e-5
GO:0048790 maintenance of presynaptic active zone structure 9.222312e-5
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 9.222312e-5
GO:0031440 regulation of mRNA 3'-end processing 9.236996e-5
GO:0050819 negative regulation of coagulation 9.449375e-5
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity 9.767032e-5
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 1.015401e-4
GO:0042730 fibrinolysis 1.034737e-4
GO:0060713 labyrinthine layer morphogenesis 1.048656e-4
GO:0006458 'de novo' protein folding 1.053558e-4
GO:0009416 response to light stimulus 1.057217e-4
GO:0016525 negative regulation of angiogenesis 1.066964e-4
GO:0009141 nucleoside triphosphate metabolic process 1.075836e-4
GO:0051045 negative regulation of membrane protein ectodomain proteolysis 1.078690e-4
GO:0051917 regulation of fibrinolysis 1.080131e-4
GO:0090026 positive regulation of monocyte chemotaxis 1.109508e-4
GO:0070988 demethylation 1.152686e-4
GO:0002891 positive regulation of immunoglobulin mediated immune response 1.261141e-4
GO:0003105 negative regulation of glomerular filtration 1.319636e-4
GO:0071356 cellular response to tumor necrosis factor 1.320010e-4
GO:0060668 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling 1.335864e-4
GO:0042886 amide transport 1.382746e-4
GO:0045343 regulation of MHC class I biosynthetic process 1.382746e-4
GO:0006766 vitamin metabolic process 1.393923e-4
GO:0048873 homeostasis of number of cells within a tissue 1.400141e-4
GO:0009260 ribonucleotide biosynthetic process 1.401845e-4
GO:0001300 chronological cell aging 1.406764e-4
GO:0016311 dephosphorylation 1.457853e-4
GO:0002922 positive regulation of humoral immune response 1.536347e-4
GO:0006749 glutathione metabolic process 1.540519e-4
GO:0051918 negative regulation of fibrinolysis 1.570297e-4
GO:0044106 cellular amine metabolic process 1.597321e-4
GO:0045017 glycerolipid biosynthetic process 1.625550e-4
GO:0006241 CTP biosynthetic process 1.678454e-4
GO:0030421 defecation 1.681429e-4
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 1.683839e-4
GO:0001893 maternal placenta development 1.695328e-4
GO:0050779 RNA destabilization 1.697222e-4
GO:0031400 negative regulation of protein modification process 1.799519e-4
GO:0006598 polyamine catabolic process 1.836298e-4
GO:0032754 positive regulation of interleukin-5 production 1.881547e-4
GO:0006590 thyroid hormone generation 1.901801e-4
GO:0061037 negative regulation of cartilage development 1.903939e-4
GO:0033209 tumor necrosis factor-mediated signaling pathway 1.930004e-4
GO:0035510 DNA dealkylation 1.962552e-4
GO:0022009 central nervous system vasculogenesis 1.999876e-4
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 1.999876e-4
GO:0006897 endocytosis 2.006811e-4
GO:0007283 spermatogenesis 2.024344e-4
GO:0042558 pteridine-containing compound metabolic process 2.053336e-4
GO:0070498 interleukin-1-mediated signaling pathway 2.076217e-4
GO:0010529 negative regulation of transposition 2.116321e-4
GO:0051084 'de novo' posttranslational protein folding 2.135833e-4
GO:0031338 regulation of vesicle fusion 2.214794e-4
GO:0008612 peptidyl-lysine modification to hypusine 2.215620e-4
GO:0009070 serine family amino acid biosynthetic process 2.219625e-4
GO:0048016 inositol phosphate-mediated signaling 2.243620e-4
GO:0070059 apoptosis in response to endoplasmic reticulum stress 2.251573e-4
GO:0044027 hypermethylation of CpG island 2.278000e-4
GO:0032703 negative regulation of interleukin-2 production 2.287892e-4
GO:0015840 urea transport 2.315836e-4
GO:0045345 positive regulation of MHC class I biosynthetic process 2.317079e-4
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 2.338913e-4
GO:0043462 regulation of ATPase activity 2.380737e-4
GO:0006090 pyruvate metabolic process 2.386166e-4
GO:0048545 response to steroid hormone stimulus 2.488544e-4
GO:0015884 folic acid transport 2.564794e-4
GO:0045777 positive regulation of blood pressure 2.623915e-4
GO:0010669 epithelial structure maintenance 2.633612e-4
GO:0006937 regulation of muscle contraction 2.636066e-4
GO:0016973 poly(A)+ mRNA export from nucleus 2.791588e-4
GO:0070633 transepithelial transport 2.794964e-4
GO:0006417 regulation of translation 2.870251e-4
GO:0034329 cell junction assembly 2.919359e-4
GO:0090257 regulation of muscle system process 2.927567e-4
GO:0006470 protein dephosphorylation 2.954613e-4
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 2.980977e-4
GO:0035039 male pronucleus assembly 3.062523e-4
GO:0048469 cell maturation 3.082647e-4
GO:0090084 negative regulation of inclusion body assembly 3.083002e-4
GO:0001894 tissue homeostasis 3.103981e-4
GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation 3.310246e-4
GO:0007274 neuromuscular synaptic transmission 3.354699e-4
GO:0010887 negative regulation of cholesterol storage 3.385055e-4
GO:0060591 chondroblast differentiation 3.387811e-4
GO:0009812 flavonoid metabolic process 3.397549e-4
GO:0071529 cementum mineralization 3.429571e-4
GO:0001986 negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure 3.429571e-4
GO:0033189 response to vitamin A 3.468925e-4
GO:0060876 semicircular canal formation 3.519288e-4
GO:0014041 regulation of neuron maturation 3.532939e-4
GO:0060306 regulation of membrane repolarization 3.563216e-4
GO:0000956 nuclear-transcribed mRNA catabolic process 3.591333e-4
GO:0007296 vitellogenesis 3.617912e-4
GO:0006457 protein folding 3.655832e-4
GO:0072334 UDP-galactose transmembrane transport 3.681503e-4
GO:0048633 positive regulation of skeletal muscle tissue growth 3.749731e-4
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 3.759447e-4
GO:0050710 negative regulation of cytokine secretion 3.764398e-4
GO:0035269 protein O-linked mannosylation 3.765722e-4
GO:0010608 posttranscriptional regulation of gene expression 3.901778e-4
GO:0034505 tooth mineralization 3.980304e-4
GO:0009152 purine ribonucleotide biosynthetic process 4.067183e-4
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 4.172312e-4
GO:0045109 intermediate filament organization 4.206022e-4
GO:0032411 positive regulation of transporter activity 4.215831e-4
GO:0090343 positive regulation of cell aging 4.264928e-4
GO:0070170 regulation of tooth mineralization 4.376610e-4
GO:0042512 negative regulation of tyrosine phosphorylation of Stat1 protein 4.406416e-4
GO:0010871 negative regulation of receptor biosynthetic process 4.437995e-4
GO:0072109 glomerular mesangium development 4.442515e-4
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 4.489757e-4
GO:0022417 protein maturation by protein folding 4.538955e-4
GO:0055067 monovalent inorganic cation homeostasis 4.568693e-4
GO:0008652 cellular amino acid biosynthetic process 4.616782e-4
GO:0015949 nucleobase-containing small molecule interconversion 4.699986e-4
GO:0070172 positive regulation of tooth mineralization 4.754585e-4
GO:0006221 pyrimidine nucleotide biosynthetic process 4.836231e-4
GO:0043046 DNA methylation involved in gamete generation 4.891015e-4
GO:0042711 maternal behavior 4.908372e-4
GO:0043163 cell envelope organization 4.931865e-4
GO:0042503 tyrosine phosphorylation of Stat3 protein 4.983481e-4
GO:0090398 cellular senescence 5.140900e-4
GO:0046618 drug export 5.175894e-4
GO:0003106 negative regulation of glomerular filtration by angiotensin 5.175894e-4
GO:0014895 smooth muscle hypertrophy 5.175894e-4
GO:0050709 negative regulation of protein secretion 5.243666e-4
GO:0032606 type I interferon production 5.300401e-4
GO:0002682 regulation of immune system process 5.370441e-4
GO:0045006 DNA deamination 5.495522e-4
GO:0002376 immune system process 5.549137e-4
GO:0048260 positive regulation of receptor-mediated endocytosis 5.577087e-4
GO:0001937 negative regulation of endothelial cell proliferation 5.593408e-4
GO:0050860 negative regulation of T cell receptor signaling pathway 5.607330e-4
GO:0002086 diaphragm contraction 5.629396e-4
GO:0009220 pyrimidine ribonucleotide biosynthetic process 5.797397e-4
GO:0006228 UTP biosynthetic process 5.881840e-4
GO:0006165 nucleoside diphosphate phosphorylation 5.881840e-4
GO:0006183 GTP biosynthetic process 5.881840e-4
GO:0046007 negative regulation of activated T cell proliferation 5.989107e-4
GO:0006306 DNA methylation 6.136483e-4
GO:0018160 peptidyl-pyrromethane cofactor linkage 6.215665e-4
GO:0031118 rRNA pseudouridine synthesis 6.215665e-4
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 6.215665e-4
GO:0023035 CD40 signaling pathway 6.215665e-4
GO:0045905 positive regulation of translational termination 6.246152e-4
GO:0006452 translational frameshifting 6.246152e-4
GO:0045901 positive regulation of translational elongation 6.246152e-4
GO:0090130 tissue migration 6.297954e-4
GO:0030853 negative regulation of granulocyte differentiation 6.338802e-4
GO:0009164 nucleoside catabolic process 6.483328e-4
GO:0006085 acetyl-CoA biosynthetic process 6.641005e-4
GO:0046697 decidualization 6.723365e-4
GO:0006007 glucose catabolic process 6.795537e-4
GO:0060084 synaptic transmission involved in micturition 6.912986e-4
GO:0061180 mammary gland epithelium development 6.982176e-4
GO:0043086 negative regulation of catalytic activity 6.992383e-4
GO:0045835 negative regulation of meiosis 7.037468e-4
GO:0030046 parallel actin filament bundle assembly 7.176191e-4
GO:0030952 establishment or maintenance of cytoskeleton polarity 7.188198e-4
GO:0015904 tetracycline transport 7.257477e-4
GO:0010987 negative regulation of high-density lipoprotein particle clearance 7.257477e-4
GO:0010897 negative regulation of triglyceride catabolic process 7.257477e-4
GO:0070489 T cell aggregation 7.424736e-4
GO:0006767 water-soluble vitamin metabolic process 7.465425e-4
GO:0090083 regulation of inclusion body assembly 7.573602e-4
GO:0046164 alcohol catabolic process 7.582524e-4
GO:0060406 positive regulation of penile erection 7.816136e-4
GO:0006402 mRNA catabolic process 7.850348e-4
GO:0009895 negative regulation of catabolic process 7.874635e-4
GO:0030035 microspike assembly 7.908043e-4
GO:0009259 ribonucleotide metabolic process 7.977267e-4
GO:0009972 cytidine deamination 7.980999e-4
GO:0071803 positive regulation of podosome assembly 7.993605e-4
GO:0072126 positive regulation of glomerular mesangial cell proliferation 8.006105e-4
GO:0071506 cellular response to mycophenolic acid 8.006105e-4
GO:0072676 lymphocyte migration 8.012309e-4
GO:0050957 equilibrioception 8.060864e-4
GO:0048872 homeostasis of number of cells 8.130886e-4
GO:0000413 protein peptidyl-prolyl isomerization 8.174406e-4
GO:0030004 cellular monovalent inorganic cation homeostasis 8.213966e-4
GO:0007265 Ras protein signal transduction 8.326870e-4
GO:0033687 osteoblast proliferation 8.565368e-4
GO:0007042 lysosomal lumen acidification 8.565368e-4
GO:0033233 regulation of protein sumoylation 8.579009e-4
GO:0043241 protein complex disassembly 8.621772e-4
GO:0006000 fructose metabolic process 8.633511e-4
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine 8.749406e-4
GO:0032786 positive regulation of transcription elongation, DNA-dependent 8.789306e-4
GO:0009987 cellular process 8.792337e-4
GO:0014043 negative regulation of neuron maturation 8.928892e-4
GO:0046483 heterocycle metabolic process 9.096666e-4
GO:0055086 nucleobase-containing small molecule metabolic process 9.479885e-4
GO:0045351 type I interferon biosynthetic process 9.482791e-4
GO:0046314 phosphocreatine biosynthetic process 9.622665e-4
GO:0060435 bronchiole development 1.002873e-3
GO:0045616 regulation of keratinocyte differentiation 1.016814e-3
GO:0032984 macromolecular complex disassembly 1.023048e-3
GO:0080111 DNA demethylation 1.036534e-3
GO:0035335 peptidyl-tyrosine dephosphorylation 1.043359e-3
GO:0001782 B cell homeostasis 1.043849e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.054965e-3
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 1.054965e-3
GO:0009218 pyrimidine ribonucleotide metabolic process 1.071690e-3
GO:0019344 cysteine biosynthetic process 1.074999e-3
GO:0003093 regulation of glomerular filtration 1.087850e-3
GO:0048871 multicellular organismal homeostasis 1.088044e-3
GO:0035247 peptidyl-arginine omega-N-methylation 1.093977e-3
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 1.100875e-3
GO:0045936 negative regulation of phosphate metabolic process 1.138333e-3
GO:0032736 positive regulation of interleukin-13 production 1.153482e-3
GO:0051180 vitamin transport 1.195183e-3
GO:0040029 regulation of gene expression, epigenetic 1.198598e-3
GO:0046292 formaldehyde metabolic process 1.219616e-3
GO:0030573 bile acid catabolic process 1.219616e-3
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 1.238699e-3
GO:0032782 bile acid secretion 1.238699e-3
GO:0072529 pyrimidine-containing compound catabolic process 1.255417e-3
GO:0031641 regulation of myelination 1.256269e-3
GO:0045630 positive regulation of T-helper 2 cell differentiation 1.283237e-3
GO:0002432 granuloma formation 1.288696e-3
GO:0008360 regulation of cell shape 1.291113e-3
GO:0060319 primitive erythrocyte differentiation 1.314902e-3
GO:0002575 basophil chemotaxis 1.314902e-3
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.338750e-3
GO:0045713 low-density lipoprotein particle receptor biosynthetic process 1.352408e-3
GO:0034441 plasma lipoprotein particle oxidation 1.352408e-3
GO:0060249 anatomical structure homeostasis 1.353443e-3
GO:0070383 DNA cytosine deamination 1.372408e-3
GO:0060457 negative regulation of digestive system process 1.372408e-3
GO:0070664 negative regulation of leukocyte proliferation 1.379807e-3
GO:0061014 positive regulation of mRNA catabolic process 1.384141e-3
GO:0012501 programmed cell death 1.385474e-3
GO:0014829 vascular smooth muscle contraction 1.406422e-3
GO:0009258 10-formyltetrahydrofolate catabolic process 1.407431e-3
GO:0061048 negative regulation of branching involved in lung morphogenesis 1.407431e-3
GO:0032753 positive regulation of interleukin-4 production 1.414405e-3
GO:0009226 nucleotide-sugar biosynthetic process 1.471629e-3
GO:0060339 negative regulation of type I interferon-mediated signaling pathway 1.472473e-3
GO:0019402 galactitol metabolic process 1.472473e-3
GO:0015728 mevalonate transport 1.472473e-3
GO:0008217 regulation of blood pressure 1.478981e-3
GO:0071281 cellular response to iron ion 1.485251e-3
GO:0010944 negative regulation of transcription by competitive promoter binding 1.493138e-3
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 1.493138e-3
GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.493138e-3
GO:0034219 carbohydrate transmembrane transport 1.494333e-3
GO:0007271 synaptic transmission, cholinergic 1.496381e-3
GO:0000212 meiotic spindle organization 1.518199e-3
GO:0009150 purine ribonucleotide metabolic process 1.535806e-3
GO:0051972 regulation of telomerase activity 1.554559e-3
GO:0031347 regulation of defense response 1.578511e-3
GO:0006835 dicarboxylic acid transport 1.592916e-3
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.603707e-3
GO:0010869 regulation of receptor biosynthetic process 1.620054e-3
GO:0003073 regulation of systemic arterial blood pressure 1.622101e-3
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway 1.623956e-3
GO:0000185 activation of MAPKKK activity 1.650946e-3
GO:0070972 protein localization in endoplasmic reticulum 1.686725e-3
GO:0046034 ATP metabolic process 1.700398e-3
GO:0030502 negative regulation of bone mineralization 1.712504e-3
GO:0044092 negative regulation of molecular function 1.725903e-3
GO:0051186 cofactor metabolic process 1.775409e-3
GO:0046680 response to DDT 1.784736e-3
GO:0060623 regulation of chromosome condensation 1.784736e-3
GO:0071283 cellular response to iron(III) ion 1.784736e-3
GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 1.784736e-3
GO:0015761 mannose transport 1.784736e-3
GO:0019413 acetate biosynthetic process 1.784736e-3
GO:0019542 propionate biosynthetic process 1.784736e-3
GO:0019752 carboxylic acid metabolic process 1.798474e-3
GO:0071299 cellular response to vitamin A 1.818053e-3
GO:0060716 labyrinthine layer blood vessel development 1.851448e-3
GO:0002316 follicular B cell differentiation 1.856066e-3
GO:0033033 negative regulation of myeloid cell apoptosis 1.862899e-3
GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine 1.862899e-3
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 1.891425e-3
GO:0048708 astrocyte differentiation 1.905828e-3
GO:0061024 membrane organization 1.924323e-3
GO:0031444 slow-twitch skeletal muscle fiber contraction 1.928096e-3
GO:0071217 cellular response to external biotic stimulus 1.958593e-3
GO:0016142 O-glycoside catabolic process 1.958593e-3
GO:0042270 protection from natural killer cell mediated cytotoxicity 1.958593e-3
GO:2000774 positive regulation of cellular senescence 2.011402e-3
GO:0035986 senescence-associated heterochromatin focus formation 2.011402e-3
GO:0016044 cellular membrane organization 2.018505e-3
GO:0045415 negative regulation of interleukin-8 biosynthetic process 2.028721e-3
GO:0001890 placenta development 2.030271e-3
GO:0046847 filopodium assembly 2.039642e-3
GO:0060351 cartilage development involved in endochondral bone morphogenesis 2.043561e-3
GO:0043534 blood vessel endothelial cell migration 2.052074e-3
GO:0071316 cellular response to nicotine 2.064116e-3
GO:0009147 pyrimidine nucleoside triphosphate metabolic process 2.070532e-3
GO:0032914 positive regulation of transforming growth factor beta1 production 2.080943e-3
GO:0060693 regulation of branching involved in salivary gland morphogenesis 2.084306e-3
GO:0006082 organic acid metabolic process 2.113239e-3
GO:0035645 enteric smooth muscle cell differentiation 2.117369e-3
GO:0006700 C21-steroid hormone biosynthetic process 2.136604e-3
GO:0001933 negative regulation of protein phosphorylation 2.182438e-3
GO:0060080 regulation of inhibitory postsynaptic membrane potential 2.230897e-3
GO:0070168 negative regulation of biomineral tissue development 2.253603e-3
GO:0010624 regulation of Schwann cell proliferation 2.264623e-3
GO:0031077 post-embryonic camera-type eye development 2.272765e-3
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 2.295916e-3
GO:0050901 leukocyte tethering or rolling 2.295969e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 2.300320e-3
GO:0035814 negative regulation of renal sodium excretion 2.304158e-3
GO:0031365 N-terminal protein amino acid modification 2.340898e-3
GO:0048384 retinoic acid receptor signaling pathway 2.357393e-3
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway 2.357491e-3
GO:0046185 aldehyde catabolic process 2.357866e-3
GO:0007202 activation of phospholipase C activity 2.360305e-3
GO:0050856 regulation of T cell receptor signaling pathway 2.389958e-3
GO:0006942 regulation of striated muscle contraction 2.398125e-3
GO:0006505 GPI anchor metabolic process 2.405941e-3
GO:0042180 cellular ketone metabolic process 2.407147e-3
GO:0009408 response to heat 2.441853e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0035094 response to nicotine 5.162701e-12
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 6.456554e-11
GO:0048298 positive regulation of isotype switching to IgA isotypes 1.611057e-10
GO:0035691 macrophage migration inhibitory factor signaling pathway 8.584097e-10
GO:0002636 positive regulation of germinal center formation 1.758536e-9
GO:0006631 fatty acid metabolic process 2.194482e-9
GO:2001021 negative regulation of response to DNA damage stimulus 2.802214e-9
GO:2000107 negative regulation of leukocyte apoptosis 3.615392e-9
GO:0090083 regulation of inclusion body assembly 4.645765e-9
GO:0002906 negative regulation of mature B cell apoptosis 9.482727e-9
GO:0070229 negative regulation of lymphocyte apoptosis 1.089274e-8
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1.159861e-8
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 1.254965e-8
GO:0002385 mucosal immune response 1.325824e-8
GO:0051006 positive regulation of lipoprotein lipase activity 1.618503e-8
GO:0019724 B cell mediated immunity 2.066811e-8
GO:0006206 pyrimidine base metabolic process 2.494748e-8
GO:0016064 immunoglobulin mediated immune response 2.677653e-8
GO:0002251 organ or tissue specific immune response 3.351730e-8
GO:0010898 positive regulation of triglyceride catabolic process 3.581972e-8
GO:0034442 regulation of lipoprotein oxidation 4.294882e-8
GO:0044255 cellular lipid metabolic process 5.527224e-8
GO:0060193 positive regulation of lipase activity 6.020695e-8
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter 6.434704e-8
GO:0002830 positive regulation of type 2 immune response 7.587367e-8
GO:0042180 cellular ketone metabolic process 9.012294e-8
GO:0006082 organic acid metabolic process 1.009537e-7
GO:0046889 positive regulation of lipid biosynthetic process 1.520028e-7
GO:0006952 defense response 1.626452e-7
GO:0090084 negative regulation of inclusion body assembly 1.750380e-7
GO:0007586 digestion 1.816381e-7
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2.318265e-7
GO:0019752 carboxylic acid metabolic process 2.343868e-7
GO:0006629 lipid metabolic process 2.420127e-7
GO:0006982 response to lipid hydroperoxide 2.425350e-7
GO:0002903 negative regulation of B cell apoptosis 2.587477e-7
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 3.106184e-7
GO:0050746 regulation of lipoprotein metabolic process 7.271057e-7
GO:0002443 leukocyte mediated immunity 7.956467e-7
GO:0032700 negative regulation of interleukin-17 production 8.548444e-7
GO:0021564 vagus nerve development 8.935345e-7
GO:0001516 prostaglandin biosynthetic process 9.244984e-7
GO:0051085 chaperone mediated protein folding requiring cofactor 1.017072e-6
GO:0045368 positive regulation of interleukin-13 biosynthetic process 1.040733e-6
GO:0034393 positive regulation of smooth muscle cell apoptosis 1.062136e-6
GO:0051135 positive regulation of NK T cell activation 1.120209e-6
GO:0045940 positive regulation of steroid metabolic process 1.375322e-6
GO:0006693 prostaglandin metabolic process 1.675481e-6
GO:0010896 regulation of triglyceride catabolic process 1.745486e-6
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 1.895533e-6
GO:2001020 regulation of response to DNA damage stimulus 1.913727e-6
GO:0055114 oxidation-reduction process 1.919094e-6
GO:0044281 small molecule metabolic process 2.029727e-6
GO:0072529 pyrimidine-containing compound catabolic process 2.039649e-6
GO:0002227 innate immune response in mucosa 2.102707e-6
GO:0050748 negative regulation of lipoprotein metabolic process 2.839428e-6
GO:0035082 axoneme assembly 2.988974e-6
GO:0030300 regulation of intestinal cholesterol absorption 3.087093e-6
GO:0002449 lymphocyte mediated immunity 3.227429e-6
GO:0072376 protein activation cascade 3.270998e-6
GO:0015781 pyrimidine nucleotide-sugar transport 3.374257e-6
GO:0006956 complement activation 3.468378e-6
GO:0045834 positive regulation of lipid metabolic process 3.545714e-6
GO:0001961 positive regulation of cytokine-mediated signaling pathway 3.735329e-6
GO:0032787 monocarboxylic acid metabolic process 3.782239e-6
GO:0046456 icosanoid biosynthetic process 3.881989e-6
GO:0032846 positive regulation of homeostatic process 4.148324e-6
GO:0006707 cholesterol catabolic process 4.865246e-6
GO:0021563 glossopharyngeal nerve development 5.293193e-6
GO:0061077 chaperone-mediated protein folding 5.790894e-6
GO:0006360 transcription from RNA polymerase I promoter 5.878231e-6
GO:0015914 phospholipid transport 6.554124e-6
GO:0046394 carboxylic acid biosynthetic process 6.804506e-6
GO:0002579 positive regulation of antigen processing and presentation 6.912489e-6
GO:0019229 regulation of vasoconstriction 8.414748e-6
GO:0002604 regulation of dendritic cell antigen processing and presentation 9.278867e-6
GO:0070228 regulation of lymphocyte apoptosis 1.064389e-5
GO:0006208 pyrimidine base catabolic process 1.106589e-5
GO:0009719 response to endogenous stimulus 1.250532e-5
GO:0006636 unsaturated fatty acid biosynthetic process 1.288452e-5
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 1.506100e-5
GO:0046890 regulation of lipid biosynthetic process 1.509301e-5
GO:0001562 response to protozoan 1.597030e-5
GO:0043279 response to alkaloid 1.612045e-5
GO:0006633 fatty acid biosynthetic process 1.690882e-5
GO:0009725 response to hormone stimulus 1.810060e-5
GO:0008203 cholesterol metabolic process 2.190411e-5
GO:0090208 positive regulation of triglyceride metabolic process 2.367042e-5
GO:0072329 monocarboxylic acid catabolic process 2.388613e-5
GO:0046037 GMP metabolic process 2.502270e-5
GO:0045087 innate immune response 2.507340e-5
GO:0006690 icosanoid metabolic process 2.657760e-5
GO:0048486 parasympathetic nervous system development 2.758894e-5
GO:0006991 response to sterol depletion 2.878621e-5
GO:0071316 cellular response to nicotine 2.900911e-5
GO:0019218 regulation of steroid metabolic process 3.029004e-5
GO:0044243 multicellular organismal catabolic process 3.190560e-5
GO:0051588 regulation of neurotransmitter transport 3.243968e-5
GO:0010661 positive regulation of muscle cell apoptosis 3.263171e-5
GO:0030574 collagen catabolic process 3.287569e-5
GO:0046395 carboxylic acid catabolic process 3.336713e-5
GO:0032729 positive regulation of interferon-gamma production 3.402662e-5
GO:0030157 pancreatic juice secretion 3.853519e-5
GO:0015816 glycine transport 3.853519e-5
GO:0016074 snoRNA metabolic process 3.874173e-5
GO:0009112 nucleobase metabolic process 3.877831e-5
GO:0060760 positive regulation of response to cytokine stimulus 4.046781e-5
GO:0035986 senescence-associated heterochromatin focus formation 4.302576e-5
GO:0090402 oncogene-induced senescence 4.302576e-5
GO:2000774 positive regulation of cellular senescence 4.302576e-5
GO:0045082 positive regulation of interleukin-10 biosynthetic process 4.302576e-5
GO:0008610 lipid biosynthetic process 4.419178e-5
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 4.870897e-5
GO:0007288 sperm axoneme assembly 4.941412e-5
GO:2000251 positive regulation of actin cytoskeleton reorganization 4.984466e-5
GO:0035036 sperm-egg recognition 5.342367e-5
GO:0009062 fatty acid catabolic process 5.373366e-5
GO:0021783 preganglionic parasympathetic nervous system development 5.541558e-5
GO:0032642 regulation of chemokine production 5.571265e-5
GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide 6.320929e-5
GO:0044058 regulation of digestive system process 6.325605e-5
GO:0006953 acute-phase response 6.519271e-5
GO:0045980 negative regulation of nucleotide metabolic process 7.009864e-5
GO:0016125 sterol metabolic process 7.150018e-5
GO:0033344 cholesterol efflux 7.314602e-5
GO:0002833 positive regulation of response to biotic stimulus 7.500201e-5
GO:0009071 serine family amino acid catabolic process 7.533356e-5
GO:0015790 UDP-xylose transport 7.874582e-5
GO:0015788 UDP-N-acetylglucosamine transport 7.874582e-5
GO:0071874 cellular response to norepinephrine stimulus 8.095649e-5
GO:0048016 inositol phosphate-mediated signaling 8.494418e-5
GO:0002455 humoral immune response mediated by circulating immunoglobulin 8.741211e-5
GO:0006378 mRNA polyadenylation 9.133450e-5
GO:0018342 protein prenylation 1.042257e-4
GO:0002821 positive regulation of adaptive immune response 1.091800e-4
GO:0090086 negative regulation of protein deubiquitination 1.149052e-4
GO:0030818 negative regulation of cAMP biosynthetic process 1.159164e-4
GO:0019430 removal of superoxide radicals 1.219436e-4
GO:0006066 alcohol metabolic process 1.242211e-4
GO:0045907 positive regulation of vasoconstriction 1.286445e-4
GO:0006954 inflammatory response 1.305910e-4
GO:0002699 positive regulation of immune effector process 1.310905e-4
GO:0046113 nucleobase catabolic process 1.479980e-4
GO:0002577 regulation of antigen processing and presentation 1.664261e-4
GO:0001578 microtubule bundle formation 1.848569e-4
GO:0048630 skeletal muscle tissue growth 1.909918e-4
GO:0034370 triglyceride-rich lipoprotein particle remodeling 1.920397e-4
GO:0097035 regulation of membrane lipid distribution 2.022947e-4
GO:0051001 negative regulation of nitric-oxide synthase activity 2.022947e-4
GO:0090023 positive regulation of neutrophil chemotaxis 2.130776e-4
GO:0015761 mannose transport 2.250246e-4
GO:0042744 hydrogen peroxide catabolic process 2.276377e-4
GO:0042832 defense response to protozoan 2.291035e-4
GO:0070244 negative regulation of thymocyte apoptosis 2.340901e-4
GO:0042663 regulation of endodermal cell fate specification 2.340901e-4
GO:0051702 interaction with symbiont 2.388841e-4
GO:2000106 regulation of leukocyte apoptosis 2.395074e-4
GO:0051897 positive regulation of protein kinase B signaling cascade 2.460404e-4
GO:0043627 response to estrogen stimulus 2.490772e-4
GO:0071242 cellular response to ammonium ion 2.616899e-4
GO:0006578 betaine biosynthetic process 2.684645e-4
GO:0048242 epinephrine secretion 2.863242e-4
GO:0032229 negative regulation of synaptic transmission, GABAergic 2.863317e-4
GO:0010193 response to ozone 3.043868e-4
GO:0045780 positive regulation of bone resorption 3.085129e-4
GO:0010893 positive regulation of steroid biosynthetic process 3.104419e-4
GO:0065005 protein-lipid complex assembly 3.145886e-4
GO:0010466 negative regulation of peptidase activity 3.162225e-4
GO:0030817 regulation of cAMP biosynthetic process 3.179440e-4
GO:0001706 endoderm formation 3.299977e-4
GO:0090238 positive regulation of arachidonic acid secretion 3.475446e-4
GO:0006668 sphinganine-1-phosphate metabolic process 3.481058e-4
GO:0032722 positive regulation of chemokine production 3.575292e-4
GO:0010224 response to UV-B 3.730506e-4
GO:0008535 respiratory chain complex IV assembly 3.739339e-4
GO:0046475 glycerophospholipid catabolic process 3.859971e-4
GO:0002837 regulation of immune response to tumor cell 3.952537e-4
GO:0034372 very-low-density lipoprotein particle remodeling 3.975928e-4
GO:0006663 platelet activating factor biosynthetic process 4.040901e-4
GO:0042396 phosphagen biosynthetic process 4.042913e-4
GO:0070243 regulation of thymocyte apoptosis 4.086021e-4
GO:0030799 regulation of cyclic nucleotide metabolic process 4.275169e-4
GO:0007339 binding of sperm to zona pellucida 4.325492e-4
GO:0002839 positive regulation of immune response to tumor cell 4.359906e-4
GO:0001867 complement activation, lectin pathway 4.517416e-4
GO:0030802 regulation of cyclic nucleotide biosynthetic process 4.770874e-4
GO:0046314 phosphocreatine biosynthetic process 4.783432e-4
GO:0010949 negative regulation of intestinal phytosterol absorption 4.783432e-4
GO:0045796 negative regulation of intestinal cholesterol absorption 4.783432e-4
GO:0010518 positive regulation of phospholipase activity 4.982554e-4
GO:0042269 regulation of natural killer cell mediated cytotoxicity 5.009638e-4
GO:0042267 natural killer cell mediated cytotoxicity 5.234489e-4
GO:0042304 regulation of fatty acid biosynthetic process 5.331406e-4
GO:0048148 behavioral response to cocaine 5.380355e-4
GO:0046626 regulation of insulin receptor signaling pathway 5.577582e-4
GO:0043085 positive regulation of catalytic activity 5.848602e-4
GO:0071422 succinate transmembrane transport 5.879433e-4
GO:0006994 positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway 5.879433e-4
GO:0015889 cobalamin transport 5.879433e-4
GO:0045908 negative regulation of vasodilation 6.112841e-4
GO:0050810 regulation of steroid biosynthetic process 6.242167e-4
GO:0070232 regulation of T cell apoptosis 6.381309e-4
GO:0035845 photoreceptor cell outer segment organization 6.430216e-4
GO:0045358 negative regulation of interferon-beta biosynthetic process 6.430216e-4
GO:0018344 protein geranylgeranylation 6.430216e-4
GO:0016140 O-glycoside metabolic process 6.430216e-4
GO:0030967 ER-nuclear sterol response pathway 6.477122e-4
GO:0006958 complement activation, classical pathway 6.497147e-4
GO:0034105 positive regulation of tissue remodeling 6.500310e-4
GO:0006108 malate metabolic process 6.669267e-4
GO:0046060 dATP metabolic process 6.829884e-4
GO:0046548 retinal rod cell development 6.845807e-4
GO:0000305 response to oxygen radical 7.072672e-4
GO:0030814 regulation of cAMP metabolic process 7.210434e-4
GO:0031649 heat generation 7.456666e-4
GO:0019932 second-messenger-mediated signaling 7.486610e-4
GO:0010524 positive regulation of calcium ion transport into cytosol 7.686131e-4
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 7.714351e-4
GO:0002069 columnar/cuboidal epithelial cell maturation 7.714351e-4
GO:0010873 positive regulation of cholesterol esterification 7.753088e-4
GO:0042662 negative regulation of mesodermal cell fate specification 7.875246e-4
GO:0033700 phospholipid efflux 7.891043e-4
GO:0090022 regulation of neutrophil chemotaxis 8.012837e-4
GO:0035987 endodermal cell differentiation 8.012837e-4
GO:0050778 positive regulation of immune response 8.017181e-4
GO:0001659 temperature homeostasis 8.029095e-4
GO:0046628 positive regulation of insulin receptor signaling pathway 8.264662e-4
GO:0032649 regulation of interferon-gamma production 8.450614e-4
GO:0002071 glandular epithelial cell maturation 8.471560e-4
GO:0008594 photoreceptor cell morphogenesis 8.471560e-4
GO:0006635 fatty acid beta-oxidation 8.525988e-4
GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter 8.700626e-4
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 8.700626e-4
GO:0006546 glycine catabolic process 8.700626e-4
GO:0048240 sperm capacitation 8.871780e-4
GO:0008645 hexose transport 9.035732e-4
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 9.169618e-4
GO:0071702 organic substance transport 9.291681e-4
GO:0046928 regulation of neurotransmitter secretion 9.294826e-4
GO:0044236 multicellular organismal metabolic process 9.311265e-4
GO:0019216 regulation of lipid metabolic process 9.507762e-4
GO:0002426 immunoglobulin production in mucosal tissue 9.624078e-4
GO:0032868 response to insulin stimulus 1.036591e-3
GO:0052547 regulation of peptidase activity 1.036824e-3
GO:0042129 regulation of T cell proliferation 1.040964e-3
GO:0045404 positive regulation of interleukin-4 biosynthetic process 1.080549e-3
GO:0002077 acrosome matrix dispersal 1.105161e-3
GO:0051186 cofactor metabolic process 1.108646e-3
GO:0072593 reactive oxygen species metabolic process 1.109303e-3
GO:0009988 cell-cell recognition 1.142752e-3
GO:0006705 mineralocorticoid biosynthetic process 1.159237e-3
GO:0045723 positive regulation of fatty acid biosynthetic process 1.163688e-3
GO:0014819 regulation of skeletal muscle contraction 1.173793e-3
GO:0050790 regulation of catalytic activity 1.179668e-3
GO:0010976 positive regulation of neuron projection development 1.193198e-3
GO:0043094 cellular metabolic compound salvage 1.208581e-3
GO:0050766 positive regulation of phagocytosis 1.272027e-3
GO:0051444 negative regulation of ubiquitin-protein ligase activity 1.283795e-3
GO:0019882 antigen processing and presentation 1.284749e-3
GO:0019217 regulation of fatty acid metabolic process 1.354980e-3
GO:0043434 response to peptide hormone stimulus 1.376856e-3
GO:0006383 transcription from RNA polymerase III promoter 1.379894e-3
GO:0006734 NADH metabolic process 1.390113e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 1.395255e-3
GO:0018206 peptidyl-methionine modification 1.436202e-3
GO:0006669 sphinganine-1-phosphate biosynthetic process 1.436202e-3
GO:0007493 endodermal cell fate determination 1.437873e-3
GO:0002513 tolerance induction to self antigen 1.444681e-3
GO:0035023 regulation of Rho protein signal transduction 1.448807e-3
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.499876e-3
GO:0042743 hydrogen peroxide metabolic process 1.504386e-3
GO:0048241 epinephrine transport 1.508632e-3
GO:0060913 cardiac cell fate determination 1.541039e-3
GO:0032571 response to vitamin K 1.541039e-3
GO:0072181 mesonephric duct formation 1.557877e-3
GO:0002902 regulation of B cell apoptosis 1.565652e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 1.615306e-3
GO:0071705 nitrogen compound transport 1.627719e-3
GO:0010872 regulation of cholesterol esterification 1.634657e-3
GO:0045086 positive regulation of interleukin-2 biosynthetic process 1.660510e-3
GO:0050432 catecholamine secretion 1.672128e-3
GO:0072527 pyrimidine-containing compound metabolic process 1.712893e-3
GO:0050671 positive regulation of lymphocyte proliferation 1.714781e-3
GO:0032233 positive regulation of actin filament bundle assembly 1.732494e-3
GO:0043467 regulation of generation of precursor metabolites and energy 1.733845e-3
GO:0002684 positive regulation of immune system process 1.750021e-3
GO:0032859 activation of Ral GTPase activity 1.751342e-3
GO:0042157 lipoprotein metabolic process 1.760670e-3
GO:0006641 triglyceride metabolic process 1.762464e-3
GO:0046503 glycerolipid catabolic process 1.806844e-3
GO:0051345 positive regulation of hydrolase activity 1.822092e-3
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 1.837444e-3
GO:0006801 superoxide metabolic process 1.837609e-3
GO:0043922 negative regulation by host of viral transcription 1.853583e-3
GO:0006959 humoral immune response 1.876735e-3
GO:0007109 cytokinesis, completion of separation 1.894554e-3
GO:0055090 acylglycerol homeostasis 1.905977e-3
GO:0060947 cardiac vascular smooth muscle cell differentiation 1.929877e-3
GO:0043691 reverse cholesterol transport 1.944803e-3
GO:0006760 folic acid-containing compound metabolic process 1.952727e-3
GO:0070233 negative regulation of T cell apoptosis 1.969448e-3
GO:0044259 multicellular organismal macromolecule metabolic process 1.971314e-3
GO:0010033 response to organic substance 1.984817e-3
GO:0070059 apoptosis in response to endoplasmic reticulum stress 1.994814e-3
GO:0008202 steroid metabolic process 1.995054e-3
GO:0070374 positive regulation of ERK1 and ERK2 cascade 2.021025e-3
GO:0032218 riboflavin transport 2.036889e-3
GO:0033566 gamma-tubulin complex localization 2.036889e-3
GO:0016068 type I hypersensitivity 2.036889e-3
GO:0018230 peptidyl-L-cysteine S-palmitoylation 2.036889e-3
GO:0000053 argininosuccinate metabolic process 2.036889e-3
GO:0000303 response to superoxide 2.040369e-3
GO:0045332 phospholipid translocation 2.044049e-3
GO:0016042 lipid catabolic process 2.088597e-3
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 2.106235e-3
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 2.151685e-3
GO:0032946 positive regulation of mononuclear cell proliferation 2.162166e-3
GO:0050999 regulation of nitric-oxide synthase activity 2.193912e-3
GO:0010522 regulation of calcium ion transport into cytosol 2.249080e-3
GO:0002526 acute inflammatory response 2.263373e-3
GO:0032368 regulation of lipid transport 2.273174e-3
GO:0030321 transepithelial chloride transport 2.288919e-3
GO:0031638 zymogen activation 2.321288e-3
GO:0033628 regulation of cell adhesion mediated by integrin 2.328421e-3
GO:0017004 cytochrome complex assembly 2.355629e-3
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 2.355629e-3
GO:0032963 collagen metabolic process 2.368736e-3
GO:0070665 positive regulation of leukocyte proliferation 2.388471e-3
GO:0043631 RNA polyadenylation 2.406901e-3
GO:0032025 response to cobalt ion 2.461689e-3
GO:0045089 positive regulation of innate immune response 2.479711e-3
GO:0046185 aldehyde catabolic process 2.512528e-3
GO:0046333 octopamine metabolic process 2.512528e-3
GO:0035106 operant conditioning 2.512528e-3
GO:0042309 homoiothermy 2.512528e-3
GO:0030573 bile acid catabolic process 2.512528e-3
GO:0032277 negative regulation of gonadotropin secretion 2.512701e-3
GO:0042107 cytokine metabolic process 2.515505e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 2.515505e-3
GO:0032897 negative regulation of viral transcription 2.533450e-3
GO:0032276 regulation of gonadotropin secretion 2.533450e-3
GO:0045076 regulation of interleukin-2 biosynthetic process 2.542552e-3
GO:0009611 response to wounding 2.565038e-3
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 2.571150e-3
GO:0032768 regulation of monooxygenase activity 2.636134e-3
GO:0002703 regulation of leukocyte mediated immunity 2.646535e-3
GO:0009190 cyclic nucleotide biosynthetic process 2.655734e-3
GO:0006177 GMP biosynthetic process 2.665542e-3
GO:0015844 monoamine transport 2.681866e-3
GO:0015749 monosaccharide transport 2.702536e-3
GO:0006544 glycine metabolic process 2.735624e-3
GO:0045357 regulation of interferon-beta biosynthetic process 2.739537e-3
GO:0031124 mRNA 3'-end processing 2.766221e-3
GO:0044283 small molecule biosynthetic process 2.774237e-3
GO:0071375 cellular response to peptide hormone stimulus 2.785321e-3
GO:0010273 detoxification of copper ion 2.828909e-3
GO:0070328 triglyceride homeostasis 2.861328e-3
GO:0006706 steroid catabolic process 2.919332e-3
GO:0042742 defense response to bacterium 2.930034e-3
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 2.934197e-3
GO:0070166 enamel mineralization 2.934197e-3
GO:0031999 negative regulation of fatty acid beta-oxidation 2.934197e-3
GO:0044093 positive regulation of molecular function 2.962842e-3
GO:0060051 negative regulation of protein glycosylation 3.032456e-3
GO:0032908 regulation of transforming growth factor beta1 production 3.034821e-3
GO:2000297 negative regulation of synapse maturation 3.090198e-3
GO:0039020 pronephric nephron tubule development 3.090198e-3
GO:0035565 regulation of pronephros size 3.090198e-3
GO:0000038 very long-chain fatty acid metabolic process 3.135266e-3
GO:0010288 response to lead ion 3.171407e-3
GO:0051251 positive regulation of lymphocyte activation 3.273104e-3
GO:0090031 positive regulation of steroid hormone biosynthetic process 3.334044e-3
GO:0006006 glucose metabolic process 3.371370e-3
GO:0045807 positive regulation of endocytosis 3.457847e-3
GO:0010935 regulation of macrophage cytokine production 3.512711e-3
GO:0035634 response to stilbenoid 3.527387e-3
GO:0010517 regulation of phospholipase activity 3.559702e-3
GO:0042840 D-glucuronate catabolic process 3.569001e-3
GO:0045751 negative regulation of Toll signaling pathway 3.569001e-3
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 3.569001e-3
GO:0060299 negative regulation of sarcomere organization 3.569001e-3
GO:0042228 interleukin-8 biosynthetic process 3.569001e-3
GO:0000379 tRNA-type intron splice site recognition and cleavage 3.569001e-3
GO:0035582 negative regulation of BMP signaling pathway by extracellular sequestering of BMP 3.569001e-3
GO:0006780 uroporphyrinogen III biosynthetic process 3.569001e-3
GO:0031119 tRNA pseudouridine synthesis 3.569001e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 3.569001e-3
GO:0035725 sodium ion transmembrane transport 3.603607e-3
GO:0042102 positive regulation of T cell proliferation 3.619060e-3
GO:0002697 regulation of immune effector process 3.628380e-3
GO:0031576 G2/M transition checkpoint 3.639715e-3
GO:0006821 chloride transport 3.691947e-3
GO:0008286 insulin receptor signaling pathway 3.787798e-3
GO:0051336 regulation of hydrolase activity 3.821106e-3
GO:0001909 leukocyte mediated cytotoxicity 3.823011e-3
GO:0006213 pyrimidine nucleoside metabolic process 3.836608e-3
GO:0015937 coenzyme A biosynthetic process 3.851012e-3
GO:0050830 defense response to Gram-positive bacterium 3.855532e-3
GO:0060674 placenta blood vessel development 3.872647e-3
GO:0051092 positive regulation of NF-kappaB transcription factor activity 3.988362e-3
GO:0046847 filopodium assembly 4.020279e-3
GO:0018345 protein palmitoylation 4.066897e-3
GO:0006725 cellular aromatic compound metabolic process 4.151556e-3
GO:0033085 negative regulation of T cell differentiation in thymus 4.201080e-3
GO:0014070 response to organic cyclic compound 4.231228e-3
GO:0009124 nucleoside monophosphate biosynthetic process 4.382140e-3
GO:0060191 regulation of lipase activity 4.490238e-3
GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter 4.496834e-3
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 4.496834e-3
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 4.496834e-3
GO:0032869 cellular response to insulin stimulus 4.544167e-3
GO:0045625 regulation of T-helper 1 cell differentiation 4.552094e-3
GO:0046514 ceramide catabolic process 4.605051e-3
GO:0071731 response to nitric oxide 4.647272e-3
GO:0021554 optic nerve development 4.647272e-3
GO:0046880 regulation of follicle-stimulating hormone secretion 4.689603e-3
GO:0051856 adhesion to symbiont 4.754278e-3
GO:0051341 regulation of oxidoreductase activity 4.755639e-3
GO:0048545 response to steroid hormone stimulus 4.763832e-3
GO:0044282 small molecule catabolic process 4.772483e-3
GO:0007205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway 4.800754e-3
GO:0097152 mesenchymal cell apoptosis 4.818462e-3
GO:0003273 cell migration involved in endocardial cushion formation 4.818462e-3
GO:0015758 glucose transport 4.968027e-3
GO:0006030 chitin metabolic process 5.017002e-3
GO:0010876 lipid localization 5.021263e-3
GO:0010863 positive regulation of phospholipase C activity 5.024226e-3
GO:0042104 positive regulation of activated T cell proliferation 5.071282e-3
GO:0042094 interleukin-2 biosynthetic process 5.163251e-3
GO:0046882 negative regulation of follicle-stimulating hormone secretion 5.163251e-3
GO:0071257 cellular response to electrical stimulus 5.214030e-3
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 5.234443e-3
GO:0001895 retina homeostasis 5.234443e-3
GO:0061078 positive regulation of prostaglandin secretion involved in immune response 5.250442e-3
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 5.250442e-3
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 5.250442e-3
GO:0045362 positive regulation of interleukin-1 biosynthetic process 5.250442e-3
GO:0002365 gamma-delta T cell lineage commitment 5.250442e-3
GO:0016142 O-glycoside catabolic process 5.250442e-3
GO:0032620 interleukin-17 production 5.250442e-3
GO:0032707 negative regulation of interleukin-23 production 5.250442e-3
GO:0010951 negative regulation of endopeptidase activity 5.332064e-3
GO:0035025 positive regulation of Rho protein signal transduction 5.389509e-3
GO:0032863 activation of Rac GTPase activity 5.389509e-3
GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 5.389509e-3
GO:0009314 response to radiation 5.428400e-3
GO:0044242 cellular lipid catabolic process 5.430510e-3
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 5.482167e-3
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway 5.482167e-3
GO:0042089 cytokine biosynthetic process 5.489128e-3
GO:0006110 regulation of glycolysis 5.489270e-3
GO:0005996 monosaccharide metabolic process 5.491844e-3
GO:0070682 proteasome regulatory particle assembly 5.606087e-3
GO:0018158 protein oxidation 5.606087e-3
GO:0035129 post-embryonic hindlimb morphogenesis 5.606087e-3
GO:0006955 immune response 5.757267e-3
GO:0043248 proteasome assembly 5.875275e-3
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 5.990519e-3
GO:0001660 fever generation 6.009410e-3
GO:0050760 negative regulation of thymidylate synthase biosynthetic process 6.030945e-3
GO:0015732 prostaglandin transport 6.030945e-3
GO:0002706 regulation of lymphocyte mediated immunity 6.043150e-3
GO:0035066 positive regulation of histone acetylation 6.066982e-3
GO:0051084 'de novo' posttranslational protein folding 6.139544e-3
GO:0048268 clathrin coat assembly 6.148217e-3
GO:0071495 cellular response to endogenous stimulus 6.151896e-3
GO:0045329 carnitine biosynthetic process 6.163549e-3
GO:0033278 cell proliferation in midbrain 6.163549e-3
GO:0019585 glucuronate metabolic process 6.190537e-3
GO:0050909 sensory perception of taste 6.211293e-3
GO:0060056 mammary gland involution 6.223158e-3
GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback 6.227930e-3
GO:0001711 endodermal cell fate commitment 6.251839e-3
GO:0001736 establishment of planar polarity 6.251839e-3
GO:0022614 membrane to membrane docking 6.256999e-3
GO:0042035 regulation of cytokine biosynthetic process 6.319637e-3
GO:0050714 positive regulation of protein secretion 6.406511e-3
GO:0051851 modification by host of symbiont morphology or physiology 6.444773e-3
GO:0035813 regulation of renal sodium excretion 6.483918e-3
GO:0006968 cellular defense response 6.499816e-3
GO:0006282 regulation of DNA repair 6.514379e-3
GO:0006555 methionine metabolic process 6.585091e-3
GO:0006869 lipid transport 6.618508e-3
GO:0042986 positive regulation of amyloid precursor protein biosynthetic process 6.628448e-3
GO:0021853 cerebral cortex GABAergic interneuron migration 6.628448e-3
GO:0032769 negative regulation of monooxygenase activity 6.660305e-3
GO:0007202 activation of phospholipase C activity 6.758829e-3
GO:0051496 positive regulation of stress fiber assembly 6.779554e-3
GO:0007164 establishment of tissue polarity 6.838907e-3
GO:0050994 regulation of lipid catabolic process 6.852678e-3
GO:0034391 regulation of smooth muscle cell apoptosis 6.866111e-3
GO:0060346 bone trabecula formation 6.885817e-3
GO:0002252 immune effector process 6.895114e-3
GO:0030168 platelet activation 7.036210e-3
GO:0009116 nucleoside metabolic process 7.066316e-3
GO:0043101 purine-containing compound salvage 7.168844e-3
GO:0019730 antimicrobial humoral response 7.168844e-3
GO:0015840 urea transport 7.168844e-3
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 7.244096e-3
GO:0034505 tooth mineralization 7.260578e-3