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Novel motif:66

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name:motif66_ACCGRTCA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0000075 cell cycle checkpoint 1.015005e-9
GO:0016071 mRNA metabolic process 1.376030e-9
GO:0051320 S phase 1.423869e-9
GO:0016574 histone ubiquitination 1.484186e-9
GO:0065004 protein-DNA complex assembly 1.951621e-9
GO:0006334 nucleosome assembly 6.584413e-9
GO:0006259 DNA metabolic process 7.660741e-9
GO:0031497 chromatin assembly 2.048582e-8
GO:0043316 cytotoxic T cell degranulation 4.513280e-8
GO:0033314 mitotic cell cycle DNA replication checkpoint 7.958157e-8
GO:0022403 cell cycle phase 8.393494e-8
GO:0006323 DNA packaging 9.902063e-8
GO:0070159 mitochondrial threonyl-tRNA aminoacylation 1.030336e-7
GO:0006281 DNA repair 1.043887e-7
GO:0000278 mitotic cell cycle 1.190387e-7
GO:0006807 nitrogen compound metabolic process 1.476675e-7
GO:0010564 regulation of cell cycle process 1.605664e-7
GO:0071156 regulation of cell cycle arrest 1.674863e-7
GO:0070535 histone H2A K63-linked ubiquitination 2.376011e-7
GO:0006397 mRNA processing 2.390791e-7
GO:0071103 DNA conformation change 2.684460e-7
GO:0046605 regulation of centrosome cycle 3.915154e-7
GO:0051438 regulation of ubiquitin-protein ligase activity 4.930716e-7
GO:0071824 protein-DNA complex subunit organization 5.633217e-7
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 5.968685e-7
GO:0051340 regulation of ligase activity 6.919717e-7
GO:0034641 cellular nitrogen compound metabolic process 7.055903e-7
GO:0006139 nucleobase-containing compound metabolic process 8.403345e-7
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 1.179277e-6
GO:0021905 forebrain-midbrain boundary formation 1.179277e-6
GO:0003322 pancreatic A cell development 1.179277e-6
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 1.179277e-6
GO:0000398 nuclear mRNA splicing, via spliceosome 1.190486e-6
GO:0000375 RNA splicing, via transesterification reactions 1.234728e-6
GO:0021903 rostrocaudal neural tube patterning 1.644347e-6
GO:0071934 thiamine transmembrane transport 1.712841e-6
GO:0090304 nucleic acid metabolic process 1.741423e-6
GO:0034728 nucleosome organization 2.013530e-6
GO:0006369 termination of RNA polymerase II transcription 2.061609e-6
GO:0060066 oviduct development 2.102654e-6
GO:0032055 negative regulation of translation in response to stress 2.109817e-6
GO:0007093 mitotic cell cycle checkpoint 2.258713e-6
GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis 2.806293e-6
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 3.146997e-6
GO:0022402 cell cycle process 3.368791e-6
GO:0010498 proteasomal protein catabolic process 3.544683e-6
GO:0034622 cellular macromolecular complex assembly 3.547129e-6
GO:0051443 positive regulation of ubiquitin-protein ligase activity 3.703590e-6
GO:0009452 RNA capping 4.520920e-6
GO:0051276 chromosome organization 4.620756e-6
GO:0051983 regulation of chromosome segregation 4.676151e-6
GO:0044265 cellular macromolecule catabolic process 4.735533e-6
GO:0006348 chromatin silencing at telomere 4.780427e-6
GO:0034621 cellular macromolecular complex subunit organization 4.950393e-6
GO:0061307 cardiac neural crest cell differentiation involved in heart development 4.984991e-6
GO:0051351 positive regulation of ligase activity 5.409933e-6
GO:0051325 interphase 6.619597e-6
GO:0042347 negative regulation of NF-kappaB import into nucleus 7.028175e-6
GO:0000084 S phase of mitotic cell cycle 7.736089e-6
GO:0033523 histone H2B ubiquitination 8.301671e-6
GO:0045019 negative regulation of nitric oxide biosynthetic process 8.446551e-6
GO:0051131 chaperone-mediated protein complex assembly 8.807469e-6
GO:0044237 cellular metabolic process 9.313028e-6
GO:0006695 cholesterol biosynthetic process 1.028978e-5
GO:0007253 cytoplasmic sequestering of NF-kappaB 1.045064e-5
GO:0044248 cellular catabolic process 1.055984e-5
GO:0044238 primary metabolic process 1.088834e-5
GO:0006473 protein acetylation 1.098853e-5
GO:0006333 chromatin assembly or disassembly 1.174697e-5
GO:0008380 RNA splicing 1.176009e-5
GO:0006396 RNA processing 1.195263e-5
GO:0002553 histamine secretion by mast cell 1.234565e-5
GO:0046853 inositol or phosphatidylinositol phosphorylation 1.238657e-5
GO:0008299 isoprenoid biosynthetic process 1.296626e-5
GO:0006398 histone mRNA 3'-end processing 1.331265e-5
GO:0006366 transcription from RNA polymerase II promoter 1.358306e-5
GO:0051220 cytoplasmic sequestering of protein 1.388295e-5
GO:0008054 cyclin catabolic process 1.563779e-5
GO:0033365 protein localization to organelle 1.779083e-5
GO:0070507 regulation of microtubule cytoskeleton organization 1.844383e-5
GO:0042994 cytoplasmic sequestering of transcription factor 2.018306e-5
GO:0048172 regulation of short-term neuronal synaptic plasticity 2.093547e-5
GO:0006370 mRNA capping 2.271443e-5
GO:0051567 histone H3-K9 methylation 2.462366e-5
GO:0021796 cerebral cortex regionalization 2.480405e-5
GO:0045540 regulation of cholesterol biosynthetic process 2.681717e-5
GO:0031576 G2/M transition checkpoint 2.693894e-5
GO:0000072 M phase specific microtubule process 2.861579e-5
GO:0002344 B cell affinity maturation 2.875968e-5
GO:0000492 box C/D snoRNP assembly 2.913618e-5
GO:0006353 transcription termination, DNA-dependent 2.990033e-5
GO:0006626 protein targeting to mitochondrion 3.118781e-5
GO:0043299 leukocyte degranulation 3.159035e-5
GO:0016126 sterol biosynthetic process 3.314726e-5
GO:0018394 peptidyl-lysine acetylation 3.408598e-5
GO:0071777 positive regulation of cell cycle cytokinesis 3.718932e-5
GO:0003266 regulation of secondary heart field cardioblast proliferation 3.773969e-5
GO:0000090 mitotic anaphase 3.909973e-5
GO:0072655 establishment of protein localization in mitochondrion 3.943165e-5
GO:0006379 mRNA cleavage 4.001988e-5
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 4.024088e-5
GO:0031117 positive regulation of microtubule depolymerization 4.024088e-5
GO:0031124 mRNA 3'-end processing 4.037112e-5
GO:0018393 internal peptidyl-lysine acetylation 4.385582e-5
GO:0007049 cell cycle 4.478954e-5
GO:0014719 satellite cell activation 4.575695e-5
GO:0035659 Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells 4.575695e-5
GO:0016090 prenol metabolic process 4.578946e-5
GO:0048285 organelle fission 4.641991e-5
GO:0033152 immunoglobulin V(D)J recombination 4.711648e-5
GO:0051464 positive regulation of cortisol secretion 5.115060e-5
GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep 5.115060e-5
GO:0006974 response to DNA damage stimulus 5.280677e-5
GO:0016567 protein ubiquitination 5.652017e-5
GO:0007506 gonadal mesoderm development 5.669136e-5
GO:0008610 lipid biosynthetic process 5.675972e-5
GO:0002448 mast cell mediated immunity 5.688520e-5
GO:0060968 regulation of gene silencing 5.743113e-5
GO:0000087 M phase of mitotic cell cycle 6.092507e-5
GO:0000076 DNA replication checkpoint 6.215755e-5
GO:0007017 microtubule-based process 6.323662e-5
GO:0043149 stress fiber assembly 6.635369e-5
GO:0070585 protein localization in mitochondrion 6.876418e-5
GO:0000216 M/G1 transition of mitotic cell cycle 6.886938e-5
GO:0070986 left/right axis specification 6.974636e-5
GO:0043555 regulation of translation in response to stress 7.226579e-5
GO:0051322 anaphase 7.331420e-5
GO:0006475 internal protein amino acid acetylation 7.350605e-5
GO:0051444 negative regulation of ubiquitin-protein ligase activity 7.609670e-5
GO:0007067 mitosis 7.707911e-5
GO:0015755 fructose transport 8.308032e-5
GO:0000733 DNA strand renaturation 8.523874e-5
GO:0032543 mitochondrial translation 9.363415e-5
GO:0000279 M phase 9.383571e-5
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 9.494905e-5
GO:0044249 cellular biosynthetic process 1.005963e-4
GO:0044257 cellular protein catabolic process 1.086114e-4
GO:0009057 macromolecule catabolic process 1.116757e-4
GO:0043320 natural killer cell degranulation 1.286898e-4
GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness 1.299829e-4
GO:0006607 NLS-bearing substrate import into nucleus 1.313367e-4
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway 1.334675e-4
GO:0002339 B cell selection 1.334675e-4
GO:0006310 DNA recombination 1.336262e-4
GO:0021983 pituitary gland development 1.409416e-4
GO:0031398 positive regulation of protein ubiquitination 1.457105e-4
GO:0043543 protein acylation 1.516224e-4
GO:2000195 negative regulation of female gonad development 1.519385e-4
GO:0010912 positive regulation of isomerase activity 1.616268e-4
GO:0031570 DNA integrity checkpoint 1.657169e-4
GO:0006325 chromatin organization 1.706261e-4
GO:2000194 regulation of female gonad development 1.706705e-4
GO:0000073 spindle pole body separation 1.729573e-4
GO:0001546 preantral ovarian follicle growth 1.729573e-4
GO:0006511 ubiquitin-dependent protein catabolic process 1.753458e-4
GO:0042992 negative regulation of transcription factor import into nucleus 1.766872e-4
GO:0051329 interphase of mitotic cell cycle 1.836762e-4
GO:0016573 histone acetylation 1.861313e-4
GO:0006283 transcription-coupled nucleotide-excision repair 1.864812e-4
GO:0009058 biosynthetic process 1.904677e-4
GO:0021523 somatic motor neuron differentiation 1.922699e-4
GO:0060236 regulation of mitotic spindle organization 1.968144e-4
GO:0048753 pigment granule organization 1.991433e-4
GO:0007059 chromosome segregation 2.001417e-4
GO:0000077 DNA damage checkpoint 2.047004e-4
GO:0060972 left/right pattern formation 2.060169e-4
GO:0006996 organelle organization 2.068884e-4
GO:0032886 regulation of microtubule-based process 2.110532e-4
GO:0046108 uridine metabolic process 2.385168e-4
GO:0014842 regulation of satellite cell proliferation 2.385168e-4
GO:0050973 detection of mechanical stimulus involved in equilibrioception 2.454808e-4
GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 2.514481e-4
GO:0007346 regulation of mitotic cell cycle 2.531477e-4
GO:0051726 regulation of cell cycle 2.560272e-4
GO:0051899 membrane depolarization 2.570056e-4
GO:0010025 wax biosynthetic process 2.590774e-4
GO:0046459 short-chain fatty acid metabolic process 2.704152e-4
GO:0019941 modification-dependent protein catabolic process 2.711522e-4
GO:0032438 melanosome organization 2.735065e-4
GO:0031123 RNA 3'-end processing 2.846916e-4
GO:0090307 spindle assembly involved in mitosis 2.883588e-4
GO:0046485 ether lipid metabolic process 2.883588e-4
GO:0034436 glycoprotein transport 2.895271e-4
GO:0031642 negative regulation of myelination 2.895271e-4
GO:0009720 detection of hormone stimulus 2.895271e-4
GO:0008152 metabolic process 2.906676e-4
GO:0035461 vitamin transmembrane transport 2.990853e-4
GO:0006986 response to unfolded protein 3.156542e-4
GO:0008611 ether lipid biosynthetic process 3.173613e-4
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 3.244374e-4
GO:0019441 tryptophan catabolic process to kynurenine 3.375061e-4
GO:0042982 amyloid precursor protein metabolic process 3.415867e-4
GO:0051603 proteolysis involved in cellular protein catabolic process 3.435125e-4
GO:0030317 sperm motility 3.525224e-4
GO:0051301 cell division 3.605827e-4
GO:0016139 glycoside catabolic process 3.696691e-4
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 3.724927e-4
GO:0070682 proteasome regulatory particle assembly 3.742363e-4
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 3.920424e-4
GO:0006605 protein targeting 4.053206e-4
GO:0090181 regulation of cholesterol metabolic process 4.155215e-4
GO:0001711 endodermal cell fate commitment 4.164151e-4
GO:0045338 farnesyl diphosphate metabolic process 4.171706e-4
GO:0006694 steroid biosynthetic process 4.235265e-4
GO:0035768 endothelial cell chemotaxis to fibroblast growth factor 4.253555e-4
GO:0035754 B cell chemotaxis 4.253555e-4
GO:0002518 lymphocyte chemotaxis across high endothelial venule 4.253555e-4
GO:0043438 acetoacetic acid metabolic process 4.281741e-4
GO:0006595 polyamine metabolic process 4.325899e-4
GO:0017038 protein import 4.331488e-4
GO:0043632 modification-dependent macromolecule catabolic process 4.369740e-4
GO:0006302 double-strand break repair 4.458056e-4
GO:0006573 valine metabolic process 4.487058e-4
GO:0002551 mast cell chemotaxis 5.242257e-4
GO:0060554 induction of necroptosis of activated-T cells 5.456601e-4
GO:0032057 negative regulation of translational initiation in response to stress 5.577300e-4
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 5.715405e-4
GO:0061303 cornea development in camera-type eye 5.715405e-4
GO:0051462 regulation of cortisol secretion 5.817152e-4
GO:0016570 histone modification 5.937263e-4
GO:0030219 megakaryocyte differentiation 6.108270e-4
GO:0019605 butyrate metabolic process 6.294801e-4
GO:0033059 cellular pigmentation 6.487506e-4
GO:0032808 lacrimal gland development 6.615673e-4
GO:0000381 regulation of alternative nuclear mRNA splicing, via spliceosome 6.822706e-4
GO:0008625 induction of apoptosis via death domain receptors 6.838998e-4
GO:0019509 L-methionine salvage from methylthioadenosine 6.904950e-4
GO:0017121 phospholipid scrambling 6.995762e-4
GO:0006659 phosphatidylserine biosynthetic process 7.152107e-4
GO:0002071 glandular epithelial cell maturation 7.152389e-4
GO:0006435 threonyl-tRNA aminoacylation 7.187438e-4
GO:0009064 glutamine family amino acid metabolic process 7.210039e-4
GO:0016569 covalent chromatin modification 7.248509e-4
GO:0009056 catabolic process 7.288416e-4
GO:0016032 viral reproduction 7.329086e-4
GO:0010824 regulation of centrosome duplication 7.344691e-4
GO:0014821 phasic smooth muscle contraction 7.438901e-4
GO:0001714 endodermal cell fate specification 7.702353e-4
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 7.851538e-4
GO:0007352 zygotic specification of dorsal/ventral axis 7.851538e-4
GO:0034394 protein localization at cell surface 7.864745e-4
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 7.975802e-4
GO:0031572 G2/M transition DNA damage checkpoint 8.038446e-4
GO:0001706 endoderm formation 8.177479e-4
GO:0070189 kynurenine metabolic process 8.229449e-4
GO:0035966 response to topologically incorrect protein 8.267980e-4
GO:0090321 positive regulation of chylomicron remnant clearance 8.444571e-4
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 8.520783e-4
GO:0000085 G2 phase of mitotic cell cycle 8.813906e-4
GO:0003264 regulation of cardioblast proliferation 9.197397e-4
GO:0035315 hair cell differentiation 9.403399e-4
GO:0010825 positive regulation of centrosome duplication 9.538184e-4
GO:0030163 protein catabolic process 9.591311e-4
GO:0032446 protein modification by small protein conjugation 9.641065e-4
GO:0048505 regulation of timing of cell differentiation 1.019000e-3
GO:0043631 RNA polyadenylation 1.042906e-3
GO:0071985 multivesicular body sorting pathway 1.053869e-3
GO:2000020 positive regulation of male gonad development 1.060274e-3
GO:0000723 telomere maintenance 1.061416e-3
GO:0006001 fructose catabolic process 1.069027e-3
GO:0001676 long-chain fatty acid metabolic process 1.069536e-3
GO:0035987 endodermal cell differentiation 1.069731e-3
GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 1.111982e-3
GO:0050684 regulation of mRNA processing 1.113031e-3
GO:0045650 negative regulation of macrophage differentiation 1.140652e-3
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 1.148847e-3
GO:0006768 biotin metabolic process 1.148847e-3
GO:0006552 leucine catabolic process 1.148847e-3
GO:0006378 mRNA polyadenylation 1.178151e-3
GO:0072594 establishment of protein localization to organelle 1.199828e-3
GO:0021707 cerebellar granule cell differentiation 1.237817e-3
GO:0019853 L-ascorbic acid biosynthetic process 1.246801e-3
GO:0010986 positive regulation of lipoprotein particle clearance 1.246801e-3
GO:0032467 positive regulation of cytokinesis 1.282144e-3
GO:0055094 response to lipoprotein stimulus 1.297008e-3
GO:0046666 retinal cell programmed cell death 1.309246e-3
GO:0070647 protein modification by small protein conjugation or removal 1.316683e-3
GO:0002329 pre-B cell differentiation 1.332472e-3
GO:0051256 spindle midzone assembly involved in mitosis 1.354179e-3
GO:0042339 keratan sulfate metabolic process 1.425045e-3
GO:0001821 histamine secretion 1.437057e-3
GO:0003272 endocardial cushion formation 1.463798e-3
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 1.487346e-3
GO:0046835 carbohydrate phosphorylation 1.492902e-3
GO:0046590 embryonic leg morphogenesis 1.492902e-3
GO:0030432 peristalsis 1.527716e-3
GO:0016447 somatic recombination of immunoglobulin gene segments 1.534210e-3
GO:2000243 positive regulation of reproductive process 1.549162e-3
GO:0006103 2-oxoglutarate metabolic process 1.553965e-3
GO:0009081 branched chain family amino acid metabolic process 1.562994e-3
GO:0000082 G1/S transition of mitotic cell cycle 1.570380e-3
GO:0070345 negative regulation of fat cell proliferation 1.587071e-3
GO:0009785 blue light signaling pathway 1.588567e-3
GO:0072249 metanephric glomerular visceral epithelial cell development 1.632338e-3
GO:0072274 metanephric glomerular basement membrane development 1.632338e-3
GO:0048677 axon extension involved in regeneration 1.632338e-3
GO:0007113 endomitotic cell cycle 1.632338e-3
GO:0009063 cellular amino acid catabolic process 1.663166e-3
GO:0043303 mast cell degranulation 1.702855e-3
GO:0060216 definitive hemopoiesis 1.706830e-3
GO:2000116 regulation of cysteine-type endopeptidase activity 1.721748e-3
GO:0060359 response to ammonium ion 1.730908e-3
GO:0001831 trophectodermal cellular morphogenesis 1.782638e-3
GO:0031112 positive regulation of microtubule polymerization or depolymerization 1.800882e-3
GO:0006895 Golgi to endosome transport 1.817257e-3
GO:0008654 phospholipid biosynthetic process 1.830940e-3
GO:0009310 amine catabolic process 1.887348e-3
GO:0009067 aspartate family amino acid biosynthetic process 1.960200e-3
GO:0007006 mitochondrial membrane organization 1.987531e-3
GO:0060409 positive regulation of acetylcholine metabolic process 2.024457e-3
GO:0007051 spindle organization 2.050234e-3
GO:0051791 medium-chain fatty acid metabolic process 2.092250e-3
GO:0031468 nuclear envelope reassembly 2.092250e-3
GO:0061072 iris morphogenesis 2.106338e-3
GO:0016476 regulation of embryonic cell shape 2.145367e-3
GO:0009223 pyrimidine deoxyribonucleotide catabolic process 2.168851e-3
GO:0043409 negative regulation of MAPKKK cascade 2.182620e-3
GO:0016137 glycoside metabolic process 2.289041e-3
GO:0010952 positive regulation of peptidase activity 2.297415e-3
GO:0009083 branched chain family amino acid catabolic process 2.347452e-3
GO:0032200 telomere organization 2.388028e-3
GO:2000227 negative regulation of pancreatic A cell differentiation 2.390066e-3
GO:2000978 negative regulation of forebrain neuron differentiation 2.390066e-3
GO:0048014 Tie receptor signaling pathway 2.390066e-3
GO:0046331 lateral inhibition 2.390066e-3
GO:0061106 negative regulation of stomach neuroendocrine cell differentiation 2.390066e-3
GO:0051608 histamine transport 2.402997e-3
GO:0018205 peptidyl-lysine modification 2.409829e-3
GO:0043923 positive regulation by host of viral transcription 2.427493e-3
GO:0008228 opsonization 2.450741e-3
GO:0046477 glycosylceramide catabolic process 2.483723e-3
GO:0045654 positive regulation of megakaryocyte differentiation 2.483723e-3
GO:0002052 positive regulation of neuroblast proliferation 2.494534e-3
GO:0035590 purinergic nucleotide receptor signaling pathway 2.573373e-3
GO:0046496 nicotinamide nucleotide metabolic process 2.622607e-3
GO:0030261 chromosome condensation 2.622680e-3
GO:0000018 regulation of DNA recombination 2.650970e-3
GO:0045746 negative regulation of Notch signaling pathway 2.652294e-3
GO:2000018 regulation of male gonad development 2.679134e-3
GO:0031133 regulation of axon diameter 2.690663e-3
GO:0021558 trochlear nerve development 2.696888e-3
GO:0006533 aspartate catabolic process 2.701207e-3
GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 2.701207e-3
GO:0035026 leading edge cell differentiation 2.701207e-3
GO:0031579 membrane raft organization 2.719990e-3
GO:0035852 horizontal cell localization 2.761125e-3
GO:2000768 positive regulation of nephron tubule epithelial cell differentiation 2.761125e-3
GO:0035849 nephric duct elongation 2.761125e-3
GO:0035502 metanephric ureteric bud development 2.761125e-3
GO:0035846 oviduct epithelium development 2.761125e-3
GO:0035847 uterine epithelium development 2.761125e-3
GO:0016525 negative regulation of angiogenesis 2.779834e-3
GO:0007005 mitochondrion organization 2.781035e-3
GO:0032861 activation of Rap GTPase activity 2.805807e-3
GO:0006601 creatine biosynthetic process 2.825519e-3
GO:0042987 amyloid precursor protein catabolic process 2.876396e-3
GO:0021877 forebrain neuron fate commitment 2.876396e-3
GO:0043388 positive regulation of DNA binding 2.982645e-3
GO:0006926 virus-infected cell apoptosis 2.986345e-3
GO:0007018 microtubule-based movement 3.095909e-3
GO:0021536 diencephalon development 3.097728e-3
GO:0003175 tricuspid valve development 3.106668e-3
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing 3.149978e-3
GO:0046968 peptide antigen transport 3.177535e-3
GO:0033151 V(D)J recombination 3.287556e-3
GO:2000833 positive regulation of steroid hormone secretion 3.307059e-3
GO:0006839 mitochondrial transport 3.404273e-3
GO:0006020 inositol metabolic process 3.424912e-3
GO:0043484 regulation of RNA splicing 3.427143e-3
GO:0045040 protein import into mitochondrial outer membrane 3.589222e-3
GO:0000188 inactivation of MAPK activity 3.644034e-3
GO:0046504 glycerol ether biosynthetic process 3.677194e-3
GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification 3.691625e-3
GO:0009912 auditory receptor cell fate commitment 3.691625e-3
GO:0051365 cellular response to potassium ion starvation 3.705190e-3
GO:0043148 mitotic spindle stabilization 3.716895e-3
GO:0051355 proprioception involved in equilibrioception 3.716895e-3
GO:0045947 negative regulation of translational initiation 3.726310e-3
GO:0006391 transcription initiation from mitochondrial promoter 3.780617e-3
GO:0006189 'de novo' IMP biosynthetic process 3.780617e-3
GO:0007595 lactation 3.912474e-3
GO:0072348 sulfur compound transport 3.953786e-3
GO:0000819 sister chromatid segregation 3.954999e-3
GO:0016445 somatic diversification of immunoglobulins 3.992694e-3
GO:0034763 negative regulation of transmembrane transport 4.048547e-3
GO:0009072 aromatic amino acid family metabolic process 4.183655e-3
GO:0016070 RNA metabolic process 4.203556e-3
GO:0043558 regulation of translational initiation in response to stress 4.242343e-3
GO:0031161 phosphatidylinositol catabolic process 4.270512e-3
GO:0007321 sperm displacement 4.270512e-3
GO:0044260 cellular macromolecule metabolic process 4.423030e-3
GO:0006271 DNA strand elongation involved in DNA replication 4.429378e-3
GO:0032185 septin cytoskeleton organization 4.433802e-3
GO:0031396 regulation of protein ubiquitination 4.517943e-3
GO:0030851 granulocyte differentiation 4.530079e-3
GO:0014074 response to purine-containing compound 4.539800e-3
GO:0010994 free ubiquitin chain polymerization 4.553070e-3
GO:0007156 homophilic cell adhesion 4.715752e-3
GO:0051255 spindle midzone assembly 4.718111e-3
GO:0007182 common-partner SMAD protein phosphorylation 4.718111e-3
GO:0042308 negative regulation of protein import into nucleus 4.749222e-3
GO:0006658 phosphatidylserine metabolic process 4.785819e-3
GO:0043933 macromolecular complex subunit organization 4.809876e-3
GO:0002639 positive regulation of immunoglobulin production 4.928968e-3
GO:0045055 regulated secretory pathway 5.054118e-3
GO:0009086 methionine biosynthetic process 5.168980e-3
GO:0008628 induction of apoptosis by hormones 5.233708e-3
GO:0006244 pyrimidine nucleotide catabolic process 5.337059e-3
GO:0035854 eosinophil fate commitment 5.350139e-3
GO:0030222 eosinophil differentiation 5.350139e-3
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 5.351383e-3
GO:0072334 UDP-galactose transmembrane transport 5.431396e-3
GO:0071242 cellular response to ammonium ion 5.431396e-3
GO:0006265 DNA topological change 5.548617e-3
GO:0051775 response to redox state 5.645778e-3
GO:0045608 negative regulation of auditory receptor cell differentiation 5.645778e-3
GO:0014827 intestine smooth muscle contraction 5.725415e-3
GO:0009637 response to blue light 5.725415e-3
GO:0010984 regulation of lipoprotein particle clearance 5.728086e-3
GO:0007029 endoplasmic reticulum organization 5.775824e-3
GO:0032507 maintenance of protein location in cell 5.810715e-3
GO:0045814 negative regulation of gene expression, epigenetic 5.838649e-3
GO:0006637 acyl-CoA metabolic process 5.847701e-3
GO:0006740 NADPH regeneration 5.965023e-3
GO:0007080 mitotic metaphase plate congression 6.165801e-3
GO:0045870 positive regulation of retroviral genome replication 6.192715e-3
GO:0002769 natural killer cell inhibitory signaling pathway 6.192715e-3
GO:2000045 regulation of G1/S transition of mitotic cell cycle 6.194153e-3
GO:0006733 oxidoreduction coenzyme metabolic process 6.224483e-3
GO:0010745 negative regulation of macrophage derived foam cell differentiation 6.242144e-3
GO:0032201 telomere maintenance via semi-conservative replication 6.278708e-3
GO:0006367 transcription initiation from RNA polymerase II promoter 6.319773e-3
GO:0006479 protein methylation 6.369499e-3
GO:0097084 vascular smooth muscle cell development 6.392745e-3
GO:0060040 retinal bipolar neuron differentiation 6.392745e-3
GO:0006116 NADH oxidation 6.422844e-3
GO:0065003 macromolecular complex assembly 6.434228e-3
GO:0021872 forebrain generation of neurons 6.458227e-3
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 6.475258e-3
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 6.545022e-3
GO:0006000 fructose metabolic process 6.580993e-3
GO:0000731 DNA synthesis involved in DNA repair 6.629327e-3
GO:0007063 regulation of sister chromatid cohesion 6.635399e-3
GO:0035587 purinergic receptor signaling pathway 6.768591e-3
GO:0000070 mitotic sister chromatid segregation 6.854864e-3
GO:0021557 oculomotor nerve development 6.920727e-3
GO:0006662 glycerol ether metabolic process 7.012934e-3
GO:0051225 spindle assembly 7.052410e-3
GO:0006536 glutamate metabolic process 7.124720e-3
GO:0034619 cellular chaperone-mediated protein complex assembly 7.156969e-3
GO:0002456 T cell mediated immunity 7.213560e-3
GO:0071844 cellular component assembly at cellular level 7.353416e-3
GO:0045008 depyrimidination 7.489155e-3
GO:0001957 intramembranous ossification 7.526189e-3
GO:0090084 negative regulation of inclusion body assembly 7.564464e-3
GO:0051313 attachment of spindle microtubules to chromosome 7.637837e-3
GO:0030856 regulation of epithelial cell differentiation 7.757317e-3
GO:0021984 adenohypophysis development 7.769833e-3
GO:0003310 pancreatic A cell differentiation 7.883787e-3
GO:0031952 regulation of protein autophosphorylation 7.925306e-3
GO:0033344 cholesterol efflux 8.032201e-3
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 8.064408e-3
GO:0090068 positive regulation of cell cycle process 8.106747e-3
GO:0033092 positive regulation of immature T cell proliferation in thymus 8.218315e-3
GO:0021517 ventral spinal cord development 8.256502e-3
GO:0048015 phosphatidylinositol-mediated signaling 8.305955e-3
GO:0021683 cerebellar granular layer morphogenesis 8.341430e-3
GO:0033238 regulation of cellular amine metabolic process 8.349010e-3
GO:0001704 formation of primary germ layer 8.372110e-3
GO:0006734 NADH metabolic process 8.403069e-3
GO:0055107 Golgi to secretory granule transport 8.553216e-3
GO:0090149 membrane fission involved in mitochondrial fission 8.553216e-3
GO:0051160 L-xylitol catabolic process 8.553216e-3
GO:0046370 fructose biosynthetic process 8.553216e-3
GO:0006062 sorbitol catabolic process 8.553216e-3
GO:0003374 dynamin polymerization involved in mitochondrial fission 8.553216e-3
GO:0061038 uterus morphogenesis 8.761776e-3
GO:0022616 DNA strand elongation 8.771710e-3
GO:0032536 regulation of cell projection size 8.914209e-3
GO:0019852 L-ascorbic acid metabolic process 8.963139e-3
GO:0000910 cytokinesis 9.024900e-3
GO:0048617 embryonic foregut morphogenesis 9.116592e-3
GO:0006551 leucine metabolic process 9.228968e-3
GO:0032621 interleukin-18 production 9.228968e-3
GO:0050957 equilibrioception 9.281597e-3
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 9.343906e-3
GO:0006312 mitotic recombination 9.344953e-3
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway 9.512153e-3
GO:0022605 oogenesis stage 9.636703e-3
GO:2000831 regulation of steroid hormone secretion 9.653778e-3
GO:0006913 nucleocytoplasmic transport 9.694606e-3
GO:0044281 small molecule metabolic process 9.710730e-3
GO:0031557 induction of programmed cell death in response to chemical stimulus 9.834848e-3
GO:0043280 positive regulation of caspase activity 9.986152e-3
GO:0032237 activation of store-operated calcium channel activity 1.004592e-2
GO:2000602 regulation of interphase of mitotic cell cycle 1.009437e-2
GO:0042668 auditory receptor cell fate determination 1.013519e-2
GO:0045713 low-density lipoprotein particle receptor biosynthetic process 1.014569e-2
GO:2000826 regulation of heart morphogenesis 1.016633e-2
GO:0002200 somatic diversification of immune receptors 1.019356e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0006334 nucleosome assembly 1.635400e-17
GO:0034728 nucleosome organization 9.386695e-17
GO:0031497 chromatin assembly 3.940995e-15
GO:0065004 protein-DNA complex assembly 8.888518e-15
GO:0006333 chromatin assembly or disassembly 2.062082e-14
GO:0071824 protein-DNA complex subunit organization 2.292289e-14
GO:0007283 spermatogenesis 8.733324e-14
GO:0071103 DNA conformation change 2.764090e-13
GO:0006323 DNA packaging 1.168165e-12
GO:0051276 chromosome organization 1.075129e-10
GO:0007276 gamete generation 1.483458e-10
GO:0006986 response to unfolded protein 4.203903e-10
GO:0060968 regulation of gene silencing 4.498855e-10
GO:0030970 retrograde protein transport, ER to cytosol 1.766923e-9
GO:0090307 spindle assembly involved in mitosis 2.273360e-9
GO:0006325 chromatin organization 3.030007e-9
GO:0019953 sexual reproduction 4.463288e-9
GO:0030968 endoplasmic reticulum unfolded protein response 2.089634e-8
GO:0035966 response to topologically incorrect protein 3.319583e-8
GO:0043503 skeletal muscle fiber adaptation 7.733978e-8
GO:0030210 heparin biosynthetic process 1.551777e-7
GO:0006259 DNA metabolic process 1.685968e-7
GO:0071777 positive regulation of cell cycle cytokinesis 1.765594e-7
GO:0035967 cellular response to topologically incorrect protein 1.981100e-7
GO:0070925 organelle assembly 3.433034e-7
GO:0032782 bile acid secretion 5.302562e-7
GO:0003096 renal sodium ion transport 5.302562e-7
GO:0000279 M phase 8.650344e-7
GO:0048609 multicellular organismal reproductive process 8.697610e-7
GO:0006475 internal protein amino acid acetylation 9.644336e-7
GO:0045653 negative regulation of megakaryocyte differentiation 1.660420e-6
GO:0018393 internal peptidyl-lysine acetylation 1.726799e-6
GO:0006102 isocitrate metabolic process 1.867381e-6
GO:0006457 protein folding 1.953141e-6
GO:0018394 peptidyl-lysine acetylation 2.070776e-6
GO:0002502 peptide antigen assembly with MHC class I protein complex 2.273063e-6
GO:0007049 cell cycle 2.939300e-6
GO:0034622 cellular macromolecular complex assembly 4.009476e-6
GO:0060266 negative regulation of respiratory burst involved in inflammatory response 4.058883e-6
GO:0061034 olfactory bulb mitral cell layer development 4.579546e-6
GO:0034621 cellular macromolecular complex subunit organization 4.701882e-6
GO:0034635 glutathione transport 4.813804e-6
GO:0006473 protein acetylation 6.277680e-6
GO:0014707 branchiomeric skeletal muscle development 6.396168e-6
GO:0006099 tricarboxylic acid cycle 6.992548e-6
GO:0051932 synaptic transmission, GABAergic 7.558182e-6
GO:0080164 regulation of nitric oxide metabolic process 7.558182e-6
GO:0035750 protein localization to myelin sheath abaxonal region 7.608743e-6
GO:0032416 negative regulation of sodium:hydrogen antiporter activity 7.625732e-6
GO:0021993 initiation of neural tube closure 8.532907e-6
GO:0030202 heparin metabolic process 1.125864e-5
GO:0016139 glycoside catabolic process 1.325360e-5
GO:0006913 nucleocytoplasmic transport 1.425932e-5
GO:0021756 striatum development 1.890909e-5
GO:0006370 mRNA capping 1.901518e-5
GO:0015761 mannose transport 1.940622e-5
GO:0022403 cell cycle phase 1.947980e-5
GO:0046356 acetyl-CoA catabolic process 2.223233e-5
GO:0034976 response to endoplasmic reticulum stress 2.243576e-5
GO:0043967 histone H4 acetylation 2.289617e-5
GO:0046885 regulation of hormone biosynthetic process 2.423632e-5
GO:0046477 glycosylceramide catabolic process 2.437018e-5
GO:0016573 histone acetylation 2.463694e-5
GO:0045652 regulation of megakaryocyte differentiation 2.570170e-5
GO:0051169 nuclear transport 2.614074e-5
GO:0018205 peptidyl-lysine modification 2.781561e-5
GO:0009109 coenzyme catabolic process 3.026294e-5
GO:0046886 positive regulation of hormone biosynthetic process 3.132299e-5
GO:0021794 thalamus development 3.143422e-5
GO:0000819 sister chromatid segregation 3.259086e-5
GO:0021544 subpallium development 3.691065e-5
GO:0032859 activation of Ral GTPase activity 3.903331e-5
GO:0006482 protein demethylation 3.950268e-5
GO:0032467 positive regulation of cytokinesis 3.979522e-5
GO:0010155 regulation of proton transport 4.313380e-5
GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 4.322069e-5
GO:0006507 GPI anchor release 4.322069e-5
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.594929e-5
GO:0071922 regulation of cohesin localization to chromatin 4.882689e-5
GO:0007052 mitotic spindle organization 5.698727e-5
GO:0000070 mitotic sister chromatid segregation 5.812573e-5
GO:0051302 regulation of cell division 5.818470e-5
GO:0006450 regulation of translational fidelity 6.579710e-5
GO:0046514 ceramide catabolic process 6.683265e-5
GO:0070988 demethylation 6.748025e-5
GO:0046466 membrane lipid catabolic process 8.340959e-5
GO:0007067 mitosis 8.354117e-5
GO:0010226 response to lithium ion 8.447152e-5
GO:0034587 piRNA metabolic process 8.627441e-5
GO:0051029 rRNA transport 9.165826e-5
GO:0048011 nerve growth factor receptor signaling pathway 9.343407e-5
GO:0032465 regulation of cytokinesis 1.020291e-4
GO:0000087 M phase of mitotic cell cycle 1.032116e-4
GO:0071844 cellular component assembly at cellular level 1.035271e-4
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 1.040729e-4
GO:0051187 cofactor catabolic process 1.123139e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 1.143815e-4
GO:0006637 acyl-CoA metabolic process 1.264369e-4
GO:0006996 organelle organization 1.432622e-4
GO:0035852 horizontal cell localization 1.441831e-4
GO:0035849 nephric duct elongation 1.441831e-4
GO:2000768 positive regulation of nephron tubule epithelial cell differentiation 1.441831e-4
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.441831e-4
GO:0035847 uterine epithelium development 1.441831e-4
GO:0035846 oviduct epithelium development 1.441831e-4
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.608255e-4
GO:0009452 RNA capping 1.627505e-4
GO:0021680 cerebellar Purkinje cell layer development 1.699409e-4
GO:0070383 DNA cytosine deamination 1.704213e-4
GO:0010529 negative regulation of transposition 1.704213e-4
GO:0030433 ER-associated protein catabolic process 1.761300e-4
GO:0071379 cellular response to prostaglandin stimulus 1.797325e-4
GO:0060264 regulation of respiratory burst involved in inflammatory response 1.925216e-4
GO:0021678 third ventricle development 1.949203e-4
GO:0044260 cellular macromolecule metabolic process 2.055305e-4
GO:0006304 DNA modification 2.090344e-4
GO:0060272 embryonic skeletal joint morphogenesis 2.173958e-4
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 2.259952e-4
GO:0010025 wax biosynthetic process 2.259952e-4
GO:0016236 macroautophagy 2.320680e-4
GO:0060829 negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation 2.326917e-4
GO:0009229 thiamine diphosphate biosynthetic process 2.326917e-4
GO:0022402 cell cycle process 2.344777e-4
GO:0000045 autophagic vacuole assembly 2.547584e-4
GO:0030149 sphingolipid catabolic process 2.587439e-4
GO:0021592 fourth ventricle development 2.754200e-4
GO:0043501 skeletal muscle adaptation 2.796039e-4
GO:0021860 pyramidal neuron development 2.943284e-4
GO:0015816 glycine transport 2.996869e-4
GO:0016137 glycoside metabolic process 3.025753e-4
GO:0072498 embryonic skeletal joint development 3.098151e-4
GO:0032352 positive regulation of hormone metabolic process 3.433063e-4
GO:0043543 protein acylation 3.437908e-4
GO:0070293 renal absorption 3.471981e-4
GO:0014066 regulation of phosphatidylinositol 3-kinase cascade 3.550227e-4
GO:0021985 neurohypophysis development 3.572941e-4
GO:0051457 maintenance of protein location in nucleus 3.718602e-4
GO:0051168 nuclear export 3.764565e-4
GO:0031018 endocrine pancreas development 3.876331e-4
GO:0044267 cellular protein metabolic process 4.302253e-4
GO:0010725 regulation of primitive erythrocyte differentiation 4.459773e-4
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 4.592180e-4
GO:0006732 coenzyme metabolic process 4.735190e-4
GO:0043968 histone H2A acetylation 4.838465e-4
GO:0019377 glycolipid catabolic process 5.268925e-4
GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade 5.292569e-4
GO:0035502 metanephric ureteric bud development 5.540580e-4
GO:0051568 histone H3-K4 methylation 5.655931e-4
GO:0006704 glucocorticoid biosynthetic process 5.782395e-4
GO:0016568 chromatin modification 5.802397e-4
GO:0048002 antigen processing and presentation of peptide antigen 6.233075e-4
GO:0009108 coenzyme biosynthetic process 6.397007e-4
GO:0019882 antigen processing and presentation 6.420888e-4
GO:0043524 negative regulation of neuron apoptosis 6.939872e-4
GO:0034694 response to prostaglandin stimulus 7.138285e-4
GO:0033143 regulation of steroid hormone receptor signaling pathway 7.176099e-4
GO:0007076 mitotic chromosome condensation 7.348699e-4
GO:0035928 rRNA import into mitochondrion 7.468223e-4
GO:0021979 hypothalamus cell differentiation 7.632562e-4
GO:0072500 negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 7.693473e-4
GO:0016577 histone demethylation 7.804533e-4
GO:0031047 gene silencing by RNA 7.956941e-4
GO:0051001 negative regulation of nitric-oxide synthase activity 8.053145e-4
GO:0032594 protein transport within lipid bilayer 8.115436e-4
GO:0008206 bile acid metabolic process 8.215443e-4
GO:0048285 organelle fission 8.551661e-4
GO:0009060 aerobic respiration 9.111467e-4
GO:0006306 DNA methylation 9.448801e-4
GO:0051260 protein homooligomerization 9.449366e-4
GO:0034118 regulation of erythrocyte aggregation 9.657820e-4
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 9.657820e-4
GO:0070474 positive regulation of uterine smooth muscle contraction 9.681931e-4
GO:0007126 meiosis 1.009987e-3
GO:0006270 DNA-dependent DNA replication initiation 1.057944e-3
GO:0051781 positive regulation of cell division 1.074447e-3
GO:0032413 negative regulation of ion transmembrane transporter activity 1.088042e-3
GO:0007157 heterophilic cell-cell adhesion 1.096748e-3
GO:0007059 chromosome segregation 1.127804e-3
GO:0032350 regulation of hormone metabolic process 1.131157e-3
GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis 1.148123e-3
GO:0006984 ER-nucleus signaling pathway 1.190577e-3
GO:0021702 cerebellar Purkinje cell differentiation 1.202314e-3
GO:0032715 negative regulation of interleukin-6 production 1.228248e-3
GO:0072259 metanephric interstitial cell development 1.228978e-3
GO:0072208 metanephric smooth muscle tissue development 1.228978e-3
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 1.228978e-3
GO:0051775 response to redox state 1.228978e-3
GO:0072184 renal vesicle progenitor cell differentiation 1.228978e-3
GO:0072168 specification of anterior mesonephric tubule identity 1.228978e-3
GO:0072169 specification of posterior mesonephric tubule identity 1.228978e-3
GO:0045426 quinone cofactor biosynthetic process 1.277306e-3
GO:0042450 arginine biosynthetic process via ornithine 1.330835e-3
GO:0019676 ammonia assimilation cycle 1.330835e-3
GO:0051983 regulation of chromosome segregation 1.387768e-3
GO:0002642 positive regulation of immunoglobulin biosynthetic process 1.440272e-3
GO:0043170 macromolecule metabolic process 1.531832e-3
GO:0031999 negative regulation of fatty acid beta-oxidation 1.548241e-3
GO:0001705 ectoderm formation 1.548241e-3
GO:0051403 stress-activated MAPK cascade 1.555106e-3
GO:0046825 regulation of protein export from nucleus 1.575262e-3
GO:0042375 quinone cofactor metabolic process 1.588489e-3
GO:0043011 myeloid dendritic cell differentiation 1.635104e-3
GO:0051321 meiotic cell cycle 1.698545e-3
GO:0002329 pre-B cell differentiation 1.761743e-3
GO:0014888 striated muscle adaptation 1.825915e-3
GO:0009972 cytidine deamination 1.852157e-3
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 1.852157e-3
GO:0072183 negative regulation of nephron tubule epithelial cell differentiation 1.908560e-3
GO:0051382 kinetochore assembly 1.908560e-3
GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration 1.908560e-3
GO:0021555 midbrain-hindbrain boundary morphogenesis 1.944961e-3
GO:0007549 dosage compensation 1.944961e-3
GO:0032415 regulation of sodium:hydrogen antiporter activity 1.995188e-3
GO:0006003 fructose 2,6-bisphosphate metabolic process 1.998962e-3
GO:0035904 aorta development 2.045338e-3
GO:0045494 photoreceptor cell maintenance 2.045559e-3
GO:0016570 histone modification 2.070672e-3
GO:0021695 cerebellar cortex development 2.155255e-3
GO:0070189 kynurenine metabolic process 2.223345e-3
GO:0050658 RNA transport 2.284658e-3
GO:0071322 cellular response to carbohydrate stimulus 2.345813e-3
GO:0071816 tail-anchored membrane protein insertion into ER membrane 2.365939e-3
GO:0046323 glucose import 2.365939e-3
GO:0030033 microvillus assembly 2.365939e-3
GO:0042159 lipoprotein catabolic process 2.422122e-3
GO:0014842 regulation of satellite cell proliferation 2.479090e-3
GO:0007080 mitotic metaphase plate congression 2.496203e-3
GO:0042362 fat-soluble vitamin biosynthetic process 2.600219e-3
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 2.659135e-3
GO:0006772 thiamine metabolic process 2.661858e-3
GO:0072385 minus-end-directed organelle transport along microtubule 2.661858e-3
GO:0035087 siRNA loading onto RISC involved in RNA interference 2.750071e-3
GO:0033315 meiotic cell cycle DNA replication checkpoint 2.750071e-3
GO:0010032 meiotic chromosome condensation 2.750071e-3
GO:0001712 ectodermal cell fate commitment 2.750071e-3
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.787528e-3
GO:0007127 meiosis I 2.842011e-3
GO:0000278 mitotic cell cycle 2.876767e-3
GO:0097039 protein linear polyubiquitination 2.877979e-3
GO:0090031 positive regulation of steroid hormone biosynthetic process 2.913992e-3
GO:0050810 regulation of steroid biosynthetic process 3.031177e-3
GO:0021517 ventral spinal cord development 3.060425e-3
GO:0035434 copper ion transmembrane transport 3.081669e-3
GO:0014002 astrocyte development 3.091157e-3
GO:0010744 positive regulation of macrophage derived foam cell differentiation 3.103295e-3
GO:0032516 positive regulation of phosphoprotein phosphatase activity 3.113513e-3
GO:0044337 canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis 3.163884e-3
GO:0048143 astrocyte activation 3.264346e-3
GO:0048242 epinephrine secretion 3.275452e-3
GO:0018106 peptidyl-histidine phosphorylation 3.275452e-3
GO:0006403 RNA localization 3.287673e-3
GO:0016569 covalent chromatin modification 3.307625e-3
GO:0015698 inorganic anion transport 3.397487e-3
GO:0033552 response to vitamin B3 3.469608e-3
GO:0046135 pyrimidine nucleoside catabolic process 3.469945e-3
GO:0006084 acetyl-CoA metabolic process 3.476451e-3
GO:0032507 maintenance of protein location in cell 3.510773e-3
GO:0070076 histone lysine demethylation 3.546425e-3
GO:0018202 peptidyl-histidine modification 3.671003e-3
GO:0051496 positive regulation of stress fiber assembly 3.732589e-3
GO:0031573 intra-S DNA damage checkpoint 3.737447e-3
GO:0071333 cellular response to glucose stimulus 3.765156e-3
GO:0043149 stress fiber assembly 3.786833e-3
GO:0048840 otolith development 3.800896e-3
GO:0045454 cell redox homeostasis 3.913097e-3
GO:0030070 insulin processing 3.975014e-3
GO:0060840 artery development 4.001118e-3
GO:0018193 peptidyl-amino acid modification 4.122650e-3
GO:0072194 kidney smooth muscle tissue development 4.147028e-3
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis 4.160454e-3
GO:0032910 regulation of transforming growth factor beta3 production 4.248199e-3
GO:0003357 noradrenergic neuron differentiation 4.307718e-3
GO:0051301 cell division 4.366418e-3
GO:0045006 DNA deamination 4.401773e-3
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.401773e-3
GO:0021782 glial cell development 4.716326e-3
GO:0007229 integrin-mediated signaling pathway 4.776723e-3
GO:0061113 pancreas morphogenesis 4.810976e-3
GO:0045368 positive regulation of interleukin-13 biosynthetic process 4.810976e-3
GO:0010631 epithelial cell migration 4.849465e-3
GO:0007525 somatic muscle development 4.868573e-3
GO:0006465 signal peptide processing 4.868573e-3
GO:0006089 lactate metabolic process 4.868573e-3
GO:0033625 positive regulation of integrin activation 4.917329e-3
GO:0001732 formation of translation initiation complex 4.917329e-3
GO:0032119 sequestering of zinc ion 4.917329e-3
GO:0061370 testosterone biosynthetic process 4.924482e-3
GO:0051383 kinetochore organization 4.924482e-3
GO:0001881 receptor recycling 4.924482e-3
GO:0050760 negative regulation of thymidylate synthase biosynthetic process 4.947841e-3
GO:0007174 epidermal growth factor catabolic process 4.947841e-3
GO:0010884 positive regulation of lipid storage 5.012414e-3
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 5.071642e-3
GO:2000649 regulation of sodium ion transmembrane transporter activity 5.071642e-3
GO:0048680 positive regulation of axon regeneration 5.420818e-3
GO:0043933 macromolecular complex subunit organization 5.457667e-3
GO:0006144 purine base metabolic process 5.527057e-3
GO:0071285 cellular response to lithium ion 5.527057e-3
GO:0030002 cellular anion homeostasis 5.671551e-3
GO:0046827 positive regulation of protein export from nucleus 5.788672e-3
GO:0043508 negative regulation of JUN kinase activity 5.788672e-3
GO:0035909 aorta morphogenesis 5.900116e-3
GO:0030163 protein catabolic process 5.902112e-3
GO:0031647 regulation of protein stability 5.948890e-3
GO:0071248 cellular response to metal ion 5.963628e-3
GO:0022618 ribonucleoprotein complex assembly 6.007002e-3
GO:0006268 DNA unwinding involved in replication 6.020244e-3
GO:0021997 neural plate axis specification 6.024121e-3
GO:0006419 alanyl-tRNA aminoacylation 6.024121e-3
GO:0048708 astrocyte differentiation 6.040995e-3
GO:0060174 limb bud formation 6.040995e-3
GO:0016584 nucleosome positioning 6.105961e-3
GO:0040029 regulation of gene expression, epigenetic 6.180015e-3
GO:0048844 artery morphogenesis 6.366424e-3
GO:0048679 regulation of axon regeneration 6.397931e-3
GO:0035307 positive regulation of protein dephosphorylation 6.397931e-3
GO:0001975 response to amphetamine 6.475268e-3
GO:0006700 C21-steroid hormone biosynthetic process 6.486774e-3
GO:0046131 pyrimidine ribonucleoside metabolic process 6.544467e-3
GO:0044090 positive regulation of vacuole organization 6.614458e-3
GO:0009234 menaquinone biosynthetic process 6.614458e-3
GO:0000379 tRNA-type intron splice site recognition and cleavage 6.614458e-3
GO:0007033 vacuole organization 6.660012e-3
GO:0051186 cofactor metabolic process 6.661191e-3
GO:0097115 neurexin clustering 6.669409e-3
GO:0007021 tubulin complex assembly 6.669409e-3
GO:0007281 germ cell development 6.720669e-3
GO:0043117 positive regulation of vascular permeability 6.765047e-3
GO:0021750 vestibular nucleus development 6.765047e-3
GO:0021679 cerebellar molecular layer development 6.765047e-3
GO:0021590 cerebellum maturation 6.765047e-3
GO:0071634 regulation of transforming growth factor beta production 6.829738e-3
GO:0006730 one-carbon metabolic process 6.868460e-3
GO:0070830 tight junction assembly 6.882862e-3
GO:0035306 positive regulation of dephosphorylation 6.882862e-3
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 6.887339e-3
GO:0035910 ascending aorta morphogenesis 6.887339e-3
GO:0032769 negative regulation of monooxygenase activity 6.887339e-3
GO:0006359 regulation of transcription from RNA polymerase III promoter 6.887339e-3
GO:0006261 DNA-dependent DNA replication 6.936141e-3
GO:0006260 DNA replication 7.185353e-3
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 7.285494e-3
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 7.285494e-3
GO:0046668 regulation of retinal cell programmed cell death 7.370895e-3
GO:0071826 ribonucleoprotein complex subunit organization 7.413521e-3
GO:0060252 positive regulation of glial cell proliferation 7.542570e-3
GO:0010388 cullin deneddylation 7.542570e-3
GO:0006596 polyamine biosynthetic process 7.542570e-3
GO:0044257 cellular protein catabolic process 7.848348e-3
GO:0046039 GTP metabolic process 7.880202e-3
GO:0050821 protein stabilization 7.922982e-3
GO:0045070 positive regulation of viral genome replication 7.939839e-3
GO:0018960 4-nitrophenol metabolic process 7.961847e-3
GO:0000244 assembly of spliceosomal tri-snRNP 7.961847e-3
GO:0021670 lateral ventricle development 8.233510e-3
GO:0035519 protein K29-linked ubiquitination 8.271890e-3
GO:0045185 maintenance of protein location 8.346247e-3
GO:0002042 cell migration involved in sprouting angiogenesis 8.398856e-3
GO:0032873 negative regulation of stress-activated MAPK cascade 8.523099e-3
GO:0019538 protein metabolic process 8.618910e-3
GO:0033554 cellular response to stress 8.628932e-3
GO:0043526 neuroprotection 8.665116e-3
GO:0044272 sulfur compound biosynthetic process 8.713877e-3
GO:0006591 ornithine metabolic process 8.719807e-3
GO:0033036 macromolecule localization 8.821675e-3
GO:0060405 regulation of penile erection 8.941287e-3
GO:0070534 protein K63-linked ubiquitination 9.199526e-3
GO:0006405 RNA export from nucleus 9.269206e-3
GO:0046907 intracellular transport 9.305720e-3
GO:0030522 intracellular receptor mediated signaling pathway 9.309027e-3
GO:0046854 phosphatidylinositol phosphorylation 9.310939e-3
GO:0001678 cellular glucose homeostasis 9.359947e-3
GO:0045082 positive regulation of interleukin-10 biosynthetic process 9.469165e-3
GO:0044314 protein K27-linked ubiquitination 9.537013e-3
GO:0071228 cellular response to tumor cell 9.537013e-3
GO:0043500 muscle adaptation 9.641180e-3
GO:0018208 peptidyl-proline modification 9.689268e-3
GO:0021903 rostrocaudal neural tube patterning 9.857122e-3
GO:0001569 patterning of blood vessels 9.895504e-3
GO:0043154 negative regulation of caspase activity 9.921593e-3
GO:0035270 endocrine system development 1.003637e-2
GO:0034504 protein localization to nucleus 1.011737e-2
GO:0046014 negative regulation of T cell homeostatic proliferation 1.037393e-2
GO:0042103 positive regulation of T cell homeostatic proliferation 1.037393e-2
GO:0046836 glycolipid transport 1.037393e-2
GO:0090292 nuclear matrix anchoring at nuclear membrane 1.037393e-2
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 1.037393e-2
GO:0035562 negative regulation of chromatin binding 1.037393e-2
GO:0032600 chemokine receptor transport out of membrane raft 1.037393e-2
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.037393e-2
GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.037393e-2
GO:0032913 negative regulation of transforming growth factor beta3 production 1.037393e-2
GO:0034107 negative regulation of erythrocyte clearance 1.037393e-2
GO:0034119 negative regulation of erythrocyte aggregation 1.037393e-2
GO:0010886 positive regulation of cholesterol storage 1.037634e-2
GO:0050883 musculoskeletal movement, spinal reflex action 1.041002e-2
GO:0045634 regulation of melanocyte differentiation 1.062059e-2
GO:0032508 DNA duplex unwinding 1.062059e-2
GO:0071383 cellular response to steroid hormone stimulus 1.074615e-2
GO:2000543 positive regulation of gastrulation 1.075245e-2
GO:0021884 forebrain neuron development 1.084731e-2
GO:0046887 positive regulation of hormone secretion 1.101749e-2
GO:0046532 regulation of photoreceptor cell differentiation 1.105050e-2
GO:0021515 cell differentiation in spinal cord 1.120187e-2
GO:0044237 cellular metabolic process 1.120331e-2
GO:0019674 NAD metabolic process 1.152239e-2
GO:0070544 histone H3-K36 demethylation 1.152271e-2
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 1.156256e-2
GO:0006914 autophagy 1.170579e-2
GO:0042384 cilium assembly 1.173755e-2
GO:0072141 renal interstitial cell development 1.188534e-2
GO:0001672 regulation of chromatin assembly or disassembly 1.188534e-2
GO:0048496 maintenance of organ identity 1.188534e-2
GO:0021527 spinal cord association neuron differentiation 1.190499e-2
GO:0051028 mRNA transport 1.196084e-2
GO:0043666 regulation of phosphoprotein phosphatase activity 1.199308e-2
GO:0000413 protein peptidyl-prolyl isomerization 1.208757e-2
GO:0034383 low-density lipoprotein particle clearance 1.211277e-2
GO:0048133 male germ-line stem cell division 1.214980e-2
GO:0035441 cell migration involved in vasculogenesis 1.214980e-2
GO:0032392 DNA geometric change 1.248153e-2
GO:0071635 negative regulation of transforming growth factor beta production 1.248153e-2
GO:0042446 hormone biosynthetic process 1.254718e-2
GO:0031017 exocrine pancreas development 1.267266e-2
GO:0050796 regulation of insulin secretion 1.269021e-2
GO:0006611 protein export from nucleus 1.273193e-2
GO:0042770 signal transduction in response to DNA damage 1.273939e-2
GO:0030490 maturation of SSU-rRNA 1.277668e-2
GO:0006857 oligopeptide transport 1.277668e-2
GO:0071242 cellular response to ammonium ion 1.279260e-2
GO:0042373 vitamin K metabolic process 1.279260e-2
GO:0045875 negative regulation of sister chromatid cohesion 1.279260e-2
GO:0045345 positive regulation of MHC class I biosynthetic process 1.279260e-2
GO:0002328 pro-B cell differentiation 1.280886e-2
GO:0070060 'de novo' actin filament nucleation 1.309760e-2
GO:0008295 spermidine biosynthetic process 1.309760e-2
GO:0030240 skeletal muscle thin filament assembly 1.312204e-2
GO:0090030 regulation of steroid hormone biosynthetic process 1.314179e-2
GO:0034968 histone lysine methylation 1.315752e-2
GO:0051225 spindle assembly 1.319061e-2
GO:0046883 regulation of hormone secretion 1.324001e-2
GO:0010927 cellular component assembly involved in morphogenesis 1.333172e-2
GO:0045930 negative regulation of mitotic cell cycle 1.343760e-2
GO:0006024 glycosaminoglycan biosynthetic process 1.349115e-2
GO:0060563 neuroepithelial cell differentiation 1.350012e-2
GO:0035372 protein localization to microtubule 1.350178e-2
GO:0051238 sequestering of metal ion 1.350178e-2
GO:0031394 positive regulation of prostaglandin biosynthetic process 1.350178e-2
GO:0010724 regulation of definitive erythrocyte differentiation 1.350178e-2
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 1.350178e-2
GO:0008356 asymmetric cell division 1.350178e-2
GO:0071841 cellular component organization or biogenesis at cellular level 1.360783e-2
GO:0060022 hard palate development 1.373533e-2
GO:0015804 neutral amino acid transport 1.401682e-2
GO:0021905 forebrain-midbrain boundary formation 1.416542e-2
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 1.416542e-2
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 1.416542e-2
GO:0003322 pancreatic A cell development 1.416542e-2
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 1.417275e-2
GO:0006366 transcription from RNA polymerase II promoter 1.497776e-2
GO:0035907 dorsal aorta development 1.498670e-2
GO:0060075 regulation of resting membrane potential 1.498670e-2
GO:0016458 gene silencing 1.505947e-2
GO:0031016 pancreas development 1.507188e-2
GO:0060112 generation of ovulation cycle rhythm 1.536964e-2
GO:0018272 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine 1.536964e-2
GO:0001988 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure 1.536964e-2
GO:0045404 positive regulation of interleukin-4 biosynthetic process 1.540673e-2
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.540673e-2
GO:0051235 maintenance of location 1.548024e-2
GO:0002575 basophil chemotaxis 1.554287e-2
GO:0045333 cellular respiration 1.564373e-2
GO:0007063 regulation of sister chromatid cohesion 1.571903e-2
GO:0006677 glycosylceramide metabolic process 1.583383e-2
GO:0007051 spindle organization 1.601360e-2
GO:0071529 cementum mineralization 1.639371e-2
GO:0046591 embryonic leg joint morphogenesis 1.639371e-2
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.639371e-2
GO:0031282 regulation of guanylate cyclase activity 1.639371e-2
GO:0000041 transition metal ion transport 1.639566e-2
GO:0006354 transcription elongation, DNA-dependent 1.647178e-2
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 1.653549e-2
GO:0006406 mRNA export from nucleus 1.659886e-2
GO:0003065 positive regulation of heart rate by epinephrine 1.660556e-2
GO:0006103 2-oxoglutarate metabolic process 1.661221e-2
GO:0045022 early endosome to late endosome transport 1.668546e-2
GO:0051651 maintenance of location in cell 1.670975e-2
GO:0006821 chloride transport 1.708968e-2
GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development 1.718271e-2
GO:0015879 carnitine transport 1.718271e-2
GO:0021578 hindbrain maturation 1.718271e-2
GO:0015680 intracellular copper ion transport 1.731501e-2
GO:0044088 regulation of vacuole organization 1.731501e-2
GO:0000053 argininosuccinate metabolic process 1.731501e-2
GO:0046329 negative regulation of JNK cascade 1.747307e-2
GO:0051354 negative regulation of oxidoreductase activity 1.776767e-2
GO:0007032 endosome organization 1.776962e-2
GO:0072668 tubulin complex biogenesis 1.784061e-2
GO:0006568 tryptophan metabolic process 1.784061e-2
GO:0065003 macromolecular complex assembly 1.784134e-2