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Novel motif:67

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name:motif67_GNTAAC

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0002544 chronic inflammatory response 1.282735e-9
GO:0016476 regulation of embryonic cell shape 4.722616e-9
GO:0010038 response to metal ion 5.372973e-8
GO:0071842 cellular component organization at cellular level 1.579434e-7
GO:0016043 cellular component organization 2.020590e-7
GO:0071841 cellular component organization or biogenesis at cellular level 3.823374e-7
GO:0071840 cellular component organization or biogenesis 4.849073e-7
GO:0042221 response to chemical stimulus 5.144895e-7
GO:0051276 chromosome organization 5.505559e-7
GO:0051258 protein polymerization 6.227989e-7
GO:0042135 neurotransmitter catabolic process 9.309803e-7
GO:0006104 succinyl-CoA metabolic process 9.720722e-7
GO:0031129 inductive cell-cell signaling 1.523825e-6
GO:0070827 chromatin maintenance 1.906622e-6
GO:0035945 mitochondrial ncRNA surveillance 1.906622e-6
GO:0035946 mitochondrial mRNA surveillance 1.906622e-6
GO:0010033 response to organic substance 2.570744e-6
GO:0030299 intestinal cholesterol absorption 2.779431e-6
GO:0048619 embryonic hindgut morphogenesis 3.635822e-6
GO:0006996 organelle organization 3.636359e-6
GO:0009068 aspartate family amino acid catabolic process 6.485813e-6
GO:0009220 pyrimidine ribonucleotide biosynthetic process 6.515816e-6
GO:0032514 positive regulation of protein phosphatase type 2B activity 7.011167e-6
GO:0045666 positive regulation of neuron differentiation 8.284885e-6
GO:0007049 cell cycle 8.541846e-6
GO:0051592 response to calcium ion 9.504806e-6
GO:0030030 cell projection organization 9.919263e-6
GO:0009218 pyrimidine ribonucleotide metabolic process 1.105528e-5
GO:0008152 metabolic process 1.116634e-5
GO:0034622 cellular macromolecular complex assembly 1.218671e-5
GO:0050916 sensory perception of sweet taste 1.410697e-5
GO:0002526 acute inflammatory response 1.468294e-5
GO:2000009 negative regulation of protein localization at cell surface 1.613001e-5
GO:0032512 regulation of protein phosphatase type 2B activity 1.693436e-5
GO:0009066 aspartate family amino acid metabolic process 1.701412e-5
GO:0015949 nucleobase-containing small molecule interconversion 1.816743e-5
GO:0044237 cellular metabolic process 1.819137e-5
GO:0043030 regulation of macrophage activation 1.944270e-5
GO:0032990 cell part morphogenesis 1.976522e-5
GO:0043623 cellular protein complex assembly 2.097520e-5
GO:0006325 chromatin organization 2.121677e-5
GO:0034621 cellular macromolecular complex subunit organization 2.285155e-5
GO:0010940 positive regulation of necrotic cell death 2.362316e-5
GO:0048858 cell projection morphogenesis 2.712751e-5
GO:0033120 positive regulation of RNA splicing 2.732446e-5
GO:0009310 amine catabolic process 2.771594e-5
GO:0043503 skeletal muscle fiber adaptation 2.784372e-5
GO:0032026 response to magnesium ion 2.860017e-5
GO:0042060 wound healing 3.183477e-5
GO:0009611 response to wounding 3.212022e-5
GO:0008219 cell death 3.214837e-5
GO:0008228 opsonization 3.348431e-5
GO:0006950 response to stress 3.616525e-5
GO:0006781 succinyl-CoA pathway 3.665679e-5
GO:0034197 triglyceride transport 3.820043e-5
GO:0016265 death 4.000798e-5
GO:0032890 regulation of organic acid transport 4.066739e-5
GO:0051642 centrosome localization 4.227173e-5
GO:0007599 hemostasis 4.278972e-5
GO:0030240 skeletal muscle thin filament assembly 4.500252e-5
GO:0044238 primary metabolic process 4.546309e-5
GO:0070106 interleukin-27-mediated signaling pathway 4.721244e-5
GO:0048015 phosphatidylinositol-mediated signaling 4.907864e-5
GO:0060004 reflex 4.997249e-5
GO:0032989 cellular component morphogenesis 5.141812e-5
GO:0034763 negative regulation of transmembrane transport 5.171433e-5
GO:0007596 blood coagulation 5.367799e-5
GO:0032891 negative regulation of organic acid transport 5.384393e-5
GO:0002023 reduction of food intake in response to dietary excess 5.604380e-5
GO:0048387 negative regulation of retinoic acid receptor signaling pathway 6.482148e-5
GO:0006542 glutamine biosynthetic process 6.554453e-5
GO:0048662 negative regulation of smooth muscle cell proliferation 6.648035e-5
GO:0050896 response to stimulus 7.053772e-5
GO:0002439 chronic inflammatory response to antigenic stimulus 7.860020e-5
GO:0061034 olfactory bulb mitral cell layer development 7.967039e-5
GO:0051320 S phase 8.790155e-5
GO:0043933 macromolecular complex subunit organization 9.085375e-5
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 9.382639e-5
GO:0070562 regulation of vitamin D receptor signaling pathway 9.382639e-5
GO:0071353 cellular response to interleukin-4 9.390799e-5
GO:0000902 cell morphogenesis 9.625175e-5
GO:0090274 positive regulation of somatostatin secretion 9.770811e-5
GO:0045023 G0 to G1 transition 9.770811e-5
GO:0031334 positive regulation of protein complex assembly 1.082716e-4
GO:0060556 regulation of vitamin D biosynthetic process 1.103313e-4
GO:0044241 lipid digestion 1.154279e-4
GO:0045214 sarcomere organization 1.155191e-4
GO:0035871 protein K11-linked deubiquitination 1.194373e-4
GO:0060005 vestibular reflex 1.199409e-4
GO:0010288 response to lead ion 1.206008e-4
GO:0009987 cellular process 1.230960e-4
GO:0030538 embryonic genitalia morphogenesis 1.231644e-4
GO:0055096 low-density lipoprotein particle mediated signaling 1.266311e-4
GO:0071526 semaphorin-plexin signaling pathway 1.281511e-4
GO:0060557 positive regulation of vitamin D biosynthetic process 1.291769e-4
GO:0030827 negative regulation of cGMP biosynthetic process 1.356060e-4
GO:2000660 negative regulation of interleukin-1-mediated signaling pathway 1.452117e-4
GO:0006467 protein thiol-disulfide exchange 1.452117e-4
GO:0042420 dopamine catabolic process 1.463128e-4
GO:0010939 regulation of necrotic cell death 1.533383e-4
GO:0022402 cell cycle process 1.534232e-4
GO:0010722 regulation of ferrochelatase activity 1.580252e-4
GO:0034114 regulation of heterotypic cell-cell adhesion 1.667998e-4
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 1.667998e-4
GO:0012501 programmed cell death 1.690512e-4
GO:0006241 CTP biosynthetic process 1.694788e-4
GO:0010883 regulation of lipid storage 1.876410e-4
GO:0060191 regulation of lipase activity 1.924684e-4
GO:0051533 positive regulation of NFAT protein import into nucleus 2.036753e-4
GO:2000659 regulation of interleukin-1-mediated signaling pathway 2.040100e-4
GO:0030534 adult behavior 2.087869e-4
GO:0050878 regulation of body fluid levels 2.132447e-4
GO:0010922 positive regulation of phosphatase activity 2.157113e-4
GO:0007442 hindgut morphogenesis 2.280374e-4
GO:0006554 lysine catabolic process 2.282276e-4
GO:0072093 metanephric renal vesicle formation 2.306329e-4
GO:0048263 determination of dorsal identity 2.330099e-4
GO:0022002 negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway 2.330099e-4
GO:2000191 regulation of fatty acid transport 2.364715e-4
GO:0061048 negative regulation of branching involved in lung morphogenesis 2.445148e-4
GO:0000084 S phase of mitotic cell cycle 2.501207e-4
GO:0034391 regulation of smooth muscle cell apoptosis 2.527017e-4
GO:0030321 transepithelial chloride transport 2.535580e-4
GO:0006927 transformed cell apoptosis 2.535580e-4
GO:0001778 plasma membrane repair 2.591738e-4
GO:0031123 RNA 3'-end processing 2.817705e-4
GO:0019932 second-messenger-mediated signaling 2.978393e-4
GO:0043277 apoptotic cell clearance 3.161597e-4
GO:0023057 negative regulation of signaling 3.396401e-4
GO:0046683 response to organophosphorus 3.415809e-4
GO:0010648 negative regulation of cell communication 3.505903e-4
GO:0065003 macromolecular complex assembly 3.519717e-4
GO:0031175 neuron projection development 3.668623e-4
GO:0050917 sensory perception of umami taste 3.771102e-4
GO:0009968 negative regulation of signal transduction 3.790519e-4
GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter 3.801316e-4
GO:0033345 asparagine catabolic process via L-aspartate 3.801316e-4
GO:0034115 negative regulation of heterotypic cell-cell adhesion 3.991145e-4
GO:0042424 catecholamine catabolic process 4.040639e-4
GO:0048666 neuron development 4.079709e-4
GO:0016568 chromatin modification 4.142878e-4
GO:0009895 negative regulation of catabolic process 4.327789e-4
GO:0006925 inflammatory cell apoptosis 4.501979e-4
GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 4.651130e-4
GO:0035456 response to interferon-beta 4.700634e-4
GO:0050892 intestinal absorption 4.904765e-4
GO:0043032 positive regulation of macrophage activation 4.945382e-4
GO:0006119 oxidative phosphorylation 5.090038e-4
GO:0016570 histone modification 5.148892e-4
GO:0018283 iron incorporation into metallo-sulfur cluster 5.214031e-4
GO:0006221 pyrimidine nucleotide biosynthetic process 5.215757e-4
GO:0048585 negative regulation of response to stimulus 5.238277e-4
GO:0006915 apoptosis 5.426062e-4
GO:0071822 protein complex subunit organization 5.654041e-4
GO:0050885 neuromuscular process controlling balance 5.814385e-4
GO:0051726 regulation of cell cycle 5.986306e-4
GO:0006214 thymidine catabolic process 6.001672e-4
GO:0072092 ureteric bud invasion 6.041445e-4
GO:0006464 protein modification process 6.101213e-4
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 6.234845e-4
GO:0031124 mRNA 3'-end processing 6.621419e-4
GO:0001937 negative regulation of endothelial cell proliferation 6.657713e-4
GO:0071803 positive regulation of podosome assembly 6.880854e-4
GO:0010390 histone monoubiquitination 7.041688e-4
GO:0042133 neurotransmitter metabolic process 7.059670e-4
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 7.285786e-4
GO:0046685 response to arsenic-containing substance 7.305135e-4
GO:0048812 neuron projection morphogenesis 7.345793e-4
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 7.368994e-4
GO:0043067 regulation of programmed cell death 7.416979e-4
GO:0010921 regulation of phosphatase activity 7.440115e-4
GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein 7.610337e-4
GO:0060662 salivary gland cavitation 7.653842e-4
GO:0080135 regulation of cellular response to stress 7.723956e-4
GO:0060008 Sertoli cell differentiation 8.014189e-4
GO:0007010 cytoskeleton organization 8.470527e-4
GO:0003008 system process 8.673884e-4
GO:0048385 regulation of retinoic acid receptor signaling pathway 8.755265e-4
GO:0010738 regulation of protein kinase A signaling cascade 8.801684e-4
GO:0010941 regulation of cell death 9.175199e-4
GO:0070848 response to growth factor stimulus 9.178472e-4
GO:0018293 protein-FAD linkage 9.348013e-4
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 9.348013e-4
GO:0006953 acute-phase response 9.405978e-4
GO:0032516 positive regulation of phosphoprotein phosphatase activity 9.562836e-4
GO:0007603 phototransduction, visible light 9.562836e-4
GO:0002819 regulation of adaptive immune response 9.574057e-4
GO:0032461 positive regulation of protein oligomerization 9.738099e-4
GO:0060445 branching involved in salivary gland morphogenesis 9.823929e-4
GO:0009147 pyrimidine nucleoside triphosphate metabolic process 9.857477e-4
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 9.978277e-4
GO:0021881 Wnt receptor signaling pathway involved in forebrain neuron fate commitment 1.003048e-3
GO:0007611 learning or memory 1.010264e-3
GO:0006212 uracil catabolic process 1.014280e-3
GO:0006210 thymine catabolic process 1.014280e-3
GO:0042981 regulation of apoptosis 1.017459e-3
GO:0065008 regulation of biological quality 1.032114e-3
GO:0000086 G2/M transition of mitotic cell cycle 1.046936e-3
GO:0051893 regulation of focal adhesion assembly 1.081419e-3
GO:0006564 L-serine biosynthetic process 1.096612e-3
GO:0044267 cellular protein metabolic process 1.098756e-3
GO:0001936 regulation of endothelial cell proliferation 1.102199e-3
GO:0016569 covalent chromatin modification 1.118901e-3
GO:0022008 neurogenesis 1.121500e-3
GO:0070670 response to interleukin-4 1.129782e-3
GO:0008210 estrogen metabolic process 1.144195e-3
GO:0031639 plasminogen activation 1.146476e-3
GO:0050830 defense response to Gram-positive bacterium 1.163478e-3
GO:0048667 cell morphogenesis involved in neuron differentiation 1.170084e-3
GO:0016226 iron-sulfur cluster assembly 1.198487e-3
GO:0006447 regulation of translational initiation by iron 1.200273e-3
GO:0010743 regulation of macrophage derived foam cell differentiation 1.219529e-3
GO:0071956 cellular component maintenance at cellular level 1.274425e-3
GO:2000379 positive regulation of reactive oxygen species metabolic process 1.284451e-3
GO:0021915 neural tube development 1.313251e-3
GO:0002821 positive regulation of adaptive immune response 1.357829e-3
GO:0019538 protein metabolic process 1.370982e-3
GO:0043241 protein complex disassembly 1.429308e-3
GO:0043501 skeletal muscle adaptation 1.438336e-3
GO:0019264 glycine biosynthetic process from serine 1.451130e-3
GO:0002576 platelet degranulation 1.460351e-3
GO:0051131 chaperone-mediated protein complex assembly 1.474924e-3
GO:0035921 desmosome disassembly 1.505368e-3
GO:0070563 negative regulation of vitamin D receptor signaling pathway 1.505368e-3
GO:0050905 neuromuscular process 1.508585e-3
GO:0021781 glial cell fate commitment 1.520165e-3
GO:0007610 behavior 1.540294e-3
GO:0043412 macromolecule modification 1.552537e-3
GO:0000117 regulation of transcription involved in G2/M-phase of mitotic cell cycle 1.559512e-3
GO:0010755 regulation of plasminogen activation 1.605121e-3
GO:0032236 positive regulation of calcium ion transport via store-operated calcium channel activity 1.636784e-3
GO:0031104 dendrite regeneration 1.636950e-3
GO:0016571 histone methylation 1.664542e-3
GO:0048660 regulation of smooth muscle cell proliferation 1.672413e-3
GO:0009084 glutamine family amino acid biosynthetic process 1.677199e-3
GO:0048262 determination of dorsal/ventral asymmetry 1.696774e-3
GO:0010646 regulation of cell communication 1.713373e-3
GO:0031579 membrane raft organization 1.722870e-3
GO:0035458 cellular response to interferon-beta 1.728136e-3
GO:0045663 positive regulation of myoblast differentiation 1.734020e-3
GO:0015918 sterol transport 1.808166e-3
GO:2000334 positive regulation of blood microparticle formation 1.815443e-3
GO:0019859 thymine metabolic process 1.815443e-3
GO:0060555 induction of necroptosis by extracellular signals 1.823239e-3
GO:0002740 negative regulation of cytokine secretion involved in immune response 1.848894e-3
GO:0060677 ureteric bud elongation 1.891903e-3
GO:0044070 regulation of anion transport 1.906399e-3
GO:0006780 uroporphyrinogen III biosynthetic process 1.917898e-3
GO:0035414 negative regulation of catenin import into nucleus 1.936307e-3
GO:0071363 cellular response to growth factor stimulus 1.941319e-3
GO:0045994 positive regulation of translational initiation by iron 2.000405e-3
GO:0002037 negative regulation of L-glutamate transport 2.000405e-3
GO:0019230 proprioception 2.032332e-3
GO:0048523 negative regulation of cellular process 2.037374e-3
GO:2000121 regulation of removal of superoxide radicals 2.038179e-3
GO:0019935 cyclic-nucleotide-mediated signaling 2.072561e-3
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 2.078412e-3
GO:0006563 L-serine metabolic process 2.103237e-3
GO:0006642 triglyceride mobilization 2.108595e-3
GO:0006491 N-glycan processing 2.108595e-3
GO:0048010 vascular endothelial growth factor receptor signaling pathway 2.115701e-3
GO:0055114 oxidation-reduction process 2.117709e-3
GO:0006513 protein monoubiquitination 2.149730e-3
GO:0007597 blood coagulation, intrinsic pathway 2.213004e-3
GO:0060009 Sertoli cell development 2.229437e-3
GO:0022411 cellular component disassembly 2.251026e-3
GO:0006693 prostaglandin metabolic process 2.279744e-3
GO:0042758 long-chain fatty acid catabolic process 2.281288e-3
GO:0042413 carnitine catabolic process 2.281288e-3
GO:0007409 axonogenesis 2.283204e-3
GO:0048769 sarcomerogenesis 2.291300e-3
GO:0072376 protein activation cascade 2.339980e-3
GO:0043313 regulation of neutrophil degranulation 2.345536e-3
GO:0051895 negative regulation of focal adhesion assembly 2.386720e-3
GO:0032423 regulation of mismatch repair 2.395211e-3
GO:0032608 interferon-beta production 2.402487e-3
GO:0010825 positive regulation of centrosome duplication 2.402487e-3
GO:0030036 actin cytoskeleton organization 2.426681e-3
GO:0014866 skeletal myofibril assembly 2.437278e-3
GO:0009064 glutamine family amino acid metabolic process 2.470882e-3
GO:0030029 actin filament-based process 2.471181e-3
GO:0016310 phosphorylation 2.486500e-3
GO:0071844 cellular component assembly at cellular level 2.497770e-3
GO:0072033 renal vesicle formation 2.513125e-3
GO:0045870 positive regulation of retroviral genome replication 2.517575e-3
GO:0051043 regulation of membrane protein ectodomain proteolysis 2.527669e-3
GO:0048468 cell development 2.537813e-3
GO:0019220 regulation of phosphate metabolic process 2.565139e-3
GO:0043170 macromolecule metabolic process 2.578008e-3
GO:0032680 regulation of tumor necrosis factor production 2.599509e-3
GO:0035771 interleukin-4-mediated signaling pathway 2.607142e-3
GO:0010839 negative regulation of keratinocyte proliferation 2.607142e-3
GO:0014050 negative regulation of glutamate secretion 2.632263e-3
GO:0042176 regulation of protein catabolic process 2.633795e-3
GO:0010824 regulation of centrosome duplication 2.663370e-3
GO:0034441 plasma lipoprotein particle oxidation 2.664659e-3
GO:0001544 initiation of primordial ovarian follicle growth 2.664659e-3
GO:0009063 cellular amino acid catabolic process 2.673904e-3
GO:0070103 regulation of interleukin-6-mediated signaling pathway 2.736503e-3
GO:0070104 negative regulation of interleukin-6-mediated signaling pathway 2.753424e-3
GO:0006145 purine base catabolic process 2.753424e-3
GO:0043652 engulfment of apoptotic cell 2.780203e-3
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.780203e-3
GO:0010754 negative regulation of cGMP-mediated signaling 2.780203e-3
GO:0010751 negative regulation of nitric oxide mediated signal transduction 2.780203e-3
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 2.780203e-3
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.787715e-3
GO:0051660 establishment of centrosome localization 2.965026e-3
GO:0021540 corpus callosum morphogenesis 2.965026e-3
GO:0050877 neurological system process 2.967181e-3
GO:0022607 cellular component assembly 2.998309e-3
GO:0050890 cognition 3.002204e-3
GO:0032369 negative regulation of lipid transport 3.011065e-3
GO:0050806 positive regulation of synaptic transmission 3.022831e-3
GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine 3.037345e-3
GO:0051004 regulation of lipoprotein lipase activity 3.044875e-3
GO:0042417 dopamine metabolic process 3.091704e-3
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 3.134884e-3
GO:0007050 cell cycle arrest 3.213242e-3
GO:0001556 oocyte maturation 3.247277e-3
GO:0007007 inner mitochondrial membrane organization 3.275464e-3
GO:0051481 reduction of cytosolic calcium ion concentration 3.298428e-3
GO:0046104 thymidine metabolic process 3.343101e-3
GO:0008628 induction of apoptosis by hormones 3.343101e-3
GO:0071103 DNA conformation change 3.498325e-3
GO:0009088 threonine biosynthetic process 3.509432e-3
GO:2000345 regulation of hepatocyte proliferation 3.537970e-3
GO:0010035 response to inorganic substance 3.576630e-3
GO:0006687 glycosphingolipid metabolic process 3.587229e-3
GO:0060100 positive regulation of phagocytosis, engulfment 3.650701e-3
GO:0009615 response to virus 3.766113e-3
GO:0007435 salivary gland morphogenesis 3.831271e-3
GO:0034641 cellular nitrogen compound metabolic process 3.881140e-3
GO:0001573 ganglioside metabolic process 3.889142e-3
GO:0034393 positive regulation of smooth muscle cell apoptosis 3.941048e-3
GO:0048699 generation of neurons 3.942636e-3
GO:0006689 ganglioside catabolic process 3.953603e-3
GO:0010757 negative regulation of plasminogen activation 3.970528e-3
GO:0071447 cellular response to hydroperoxide 4.024367e-3
GO:0021797 forebrain anterior/posterior pattern specification 4.054391e-3
GO:0071025 RNA surveillance 4.093353e-3
GO:0010226 response to lithium ion 4.178415e-3
GO:0060271 cilium morphogenesis 4.217696e-3
GO:0070507 regulation of microtubule cytoskeleton organization 4.273069e-3
GO:0034498 early endosome to Golgi transport 4.346712e-3
GO:0015939 pantothenate metabolic process 4.412012e-3
GO:0044085 cellular component biogenesis 4.427462e-3
GO:0016192 vesicle-mediated transport 4.442030e-3
GO:0000904 cell morphogenesis involved in differentiation 4.465651e-3
GO:0032606 type I interferon production 4.525116e-3
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 4.527374e-3
GO:0030301 cholesterol transport 4.538901e-3
GO:0006887 exocytosis 4.558892e-3
GO:0051135 positive regulation of NK T cell activation 4.640365e-3
GO:0071636 positive regulation of transforming growth factor beta production 4.666773e-3
GO:2000143 negative regulation of transcription initiation, DNA-dependent 4.671805e-3
GO:0000416 positive regulation of histone H3-K36 methylation 4.671805e-3
GO:0009060 aerobic respiration 4.693213e-3
GO:0051325 interphase 4.706352e-3
GO:0060291 long-term synaptic potentiation 4.772178e-3
GO:0007015 actin filament organization 4.801167e-3
GO:0015911 plasma membrane long-chain fatty acid transport 4.805839e-3
GO:0035583 negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta 4.841312e-3
GO:0071675 regulation of mononuclear cell migration 4.944728e-3
GO:0043666 regulation of phosphoprotein phosphatase activity 4.954897e-3
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 4.969932e-3
GO:0010888 negative regulation of lipid storage 4.972315e-3
GO:0010759 positive regulation of macrophage chemotaxis 5.044105e-3
GO:0061041 regulation of wound healing 5.064014e-3
GO:0042044 fluid transport 5.107678e-3
GO:0051179 localization 5.113547e-3
GO:0042775 mitochondrial ATP synthesis coupled electron transport 5.127544e-3
GO:0048519 negative regulation of biological process 5.144543e-3
GO:0060548 negative regulation of cell death 5.150601e-3
GO:0032800 receptor biosynthetic process 5.174388e-3
GO:0070194 synaptonemal complex disassembly 5.176763e-3
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 5.176763e-3
GO:0015886 heme transport 5.363044e-3
GO:0045597 positive regulation of cell differentiation 5.412832e-3
GO:0019934 cGMP-mediated signaling 5.518793e-3
GO:0070271 protein complex biogenesis 5.520107e-3
GO:0002437 inflammatory response to antigenic stimulus 5.560976e-3
GO:0032501 multicellular organismal process 5.633189e-3
GO:0021553 olfactory nerve development 5.644373e-3
GO:0090304 nucleic acid metabolic process 5.646863e-3
GO:0032464 positive regulation of protein homooligomerization 5.674281e-3
GO:0046322 negative regulation of fatty acid oxidation 5.696284e-3
GO:0009586 rhodopsin mediated phototransduction 5.760490e-3
GO:0031099 regeneration 5.820401e-3
GO:0035518 histone H2A monoubiquitination 5.850501e-3
GO:0070265 necrotic cell death 5.893529e-3
GO:0015855 pyrimidine base transport 5.893529e-3
GO:0045657 positive regulation of monocyte differentiation 5.893529e-3
GO:0006461 protein complex assembly 5.933521e-3
GO:0000082 G1/S transition of mitotic cell cycle 5.980342e-3
GO:0019254 carnitine metabolic process, CoA-linked 5.998672e-3
GO:0051568 histone H3-K4 methylation 6.060659e-3
GO:0032237 activation of store-operated calcium channel activity 6.092430e-3
GO:2000503 positive regulation of natural killer cell chemotaxis 6.115948e-3
GO:2000513 positive regulation of granzyme A production 6.115948e-3
GO:2000518 negative regulation of T-helper 1 cell activation 6.115948e-3
GO:2000538 positive regulation of B cell chemotaxis 6.115948e-3
GO:0071663 positive regulation of granzyme B production 6.115948e-3
GO:2000412 positive regulation of thymocyte migration 6.115948e-3
GO:0035740 CD8-positive, alpha-beta T cell proliferation 6.115948e-3
GO:0035739 CD4-positive, alpha-beta T cell proliferation 6.115948e-3
GO:0035744 T-helper 1 cell cytokine production 6.115948e-3
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 6.134839e-3
GO:0043031 negative regulation of macrophage activation 6.176990e-3
GO:0006398 histone mRNA 3'-end processing 6.176990e-3
GO:0045218 zonula adherens maintenance 6.197383e-3
GO:0097035 regulation of membrane lipid distribution 6.217684e-3
GO:0051917 regulation of fibrinolysis 6.217684e-3
GO:0042177 negative regulation of protein catabolic process 6.346005e-3
GO:0071310 cellular response to organic substance 6.373561e-3
GO:0010758 regulation of macrophage chemotaxis 6.394005e-3
GO:0047496 vesicle transport along microtubule 6.421503e-3
GO:0051045 negative regulation of membrane protein ectodomain proteolysis 6.539118e-3
GO:0032007 negative regulation of TOR signaling cascade 6.539118e-3
GO:0015721 bile acid and bile salt transport 6.581888e-3
GO:0006958 complement activation, classical pathway 6.721610e-3
GO:0042489 negative regulation of odontogenesis of dentine-containing tooth 6.752511e-3
GO:0032959 inositol trisphosphate biosynthetic process 6.764335e-3
GO:0035924 cellular response to vascular endothelial growth factor stimulus 6.784076e-3
GO:0045626 negative regulation of T-helper 1 cell differentiation 6.793407e-3
GO:0032229 negative regulation of synaptic transmission, GABAergic 6.809448e-3
GO:0032958 inositol phosphate biosynthetic process 6.861009e-3
GO:0030049 muscle filament sliding 6.901812e-3
GO:0007431 salivary gland development 6.987668e-3
GO:0010517 regulation of phospholipase activity 7.140682e-3
GO:0070683 mitotic cell cycle G2/M transition decatenation checkpoint 7.140866e-3
GO:0021984 adenohypophysis development 7.155497e-3
GO:0032878 regulation of establishment or maintenance of cell polarity 7.195241e-3
GO:0051707 response to other organism 7.274344e-3
GO:0006807 nitrogen compound metabolic process 7.308190e-3
GO:0016070 RNA metabolic process 7.334605e-3
GO:0030194 positive regulation of blood coagulation 7.383354e-3
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway 7.440812e-3
GO:0016082 synaptic vesicle priming 7.453156e-3
GO:0001766 membrane raft polarization 7.453156e-3
GO:0002376 immune system process 7.489454e-3
GO:0001843 neural tube closure 7.518477e-3
GO:0001960 negative regulation of cytokine-mediated signaling pathway 7.589102e-3
GO:0070294 renal sodium ion absorption 7.628792e-3
GO:0030157 pancreatic juice secretion 7.642904e-3
GO:0009584 detection of visible light 7.663680e-3
GO:0006796 phosphate-containing compound metabolic process 7.710751e-3
GO:0031119 tRNA pseudouridine synthesis 7.773060e-3
GO:0035082 axoneme assembly 7.879206e-3
GO:0006265 DNA topological change 7.879206e-3
GO:0090291 negative regulation of osteoclast proliferation 7.901997e-3
GO:2000347 positive regulation of hepatocyte proliferation 7.901997e-3
GO:2000349 negative regulation of CD40 signaling pathway 7.901997e-3
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 7.901997e-3
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 7.901997e-3
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 7.901997e-3
GO:0072573 tolerance induction to lipopolysaccharide 7.901997e-3
GO:0031100 organ regeneration 7.970406e-3
GO:0071622 regulation of granulocyte chemotaxis 7.988967e-3
GO:0043069 negative regulation of programmed cell death 8.004226e-3
GO:0046131 pyrimidine ribonucleoside metabolic process 8.027929e-3
GO:0035330 regulation of hippo signaling cascade 8.028424e-3
GO:0006266 DNA ligation 8.070481e-3
GO:0060216 definitive hemopoiesis 8.074661e-3
GO:0006629 lipid metabolic process 8.100420e-3
GO:0006833 water transport 8.112016e-3
GO:0006396 RNA processing 8.183043e-3
GO:0051318 G1 phase 8.332968e-3
GO:0030838 positive regulation of actin filament polymerization 8.363356e-3
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 8.407152e-3
GO:0042308 negative regulation of protein import into nucleus 8.414697e-3
GO:0042953 lipoprotein transport 8.430832e-3
GO:0021935 cerebellar granule cell precursor tangential migration 8.454185e-3
GO:0033151 V(D)J recombination 8.485596e-3
GO:0032006 regulation of TOR signaling cascade 8.554943e-3
GO:0009653 anatomical structure morphogenesis 8.560157e-3
GO:0030162 regulation of proteolysis 8.586292e-3
GO:0048566 embryonic digestive tract development 8.642603e-3
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 8.712382e-3
GO:0060606 tube closure 8.757741e-3
GO:0001841 neural tube formation 8.840494e-3
GO:0001774 microglial cell activation 8.841722e-3
GO:0050908 detection of light stimulus involved in visual perception 8.867130e-3
GO:0050820 positive regulation of coagulation 8.874496e-3
GO:0007030 Golgi organization 8.883897e-3
GO:0060218 hemopoietic stem cell differentiation 8.909164e-3
GO:0032924 activin receptor signaling pathway 8.913478e-3
GO:0008202 steroid metabolic process 8.916124e-3
GO:0048853 forebrain morphogenesis 8.916126e-3
GO:0016567 protein ubiquitination 9.099798e-3
GO:0010815 bradykinin catabolic process 9.110299e-3
GO:0001696 gastric acid secretion 9.110299e-3
GO:0071404 cellular response to low-density lipoprotein particle stimulus 9.131767e-3
GO:0032411 positive regulation of transporter activity 9.134042e-3
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 9.212446e-3
GO:0007525 somatic muscle development 9.222318e-3
GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback 9.222318e-3
GO:0006479 protein methylation 9.288813e-3
GO:0030168 platelet activation 9.310780e-3
GO:0010955 negative regulation of protein processing 9.338543e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0050892 intestinal absorption 4.685122e-12
GO:0009410 response to xenobiotic stimulus 5.698804e-9
GO:0022600 digestive system process 4.660465e-8
GO:0060282 positive regulation of oocyte development 1.165781e-7
GO:0060281 regulation of oocyte development 1.165781e-7
GO:0032814 regulation of natural killer cell activation 2.022310e-7
GO:0001916 positive regulation of T cell mediated cytotoxicity 2.552435e-7
GO:0032423 regulation of mismatch repair 5.461325e-7
GO:0006805 xenobiotic metabolic process 6.315976e-7
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 9.142123e-7
GO:0001914 regulation of T cell mediated cytotoxicity 1.091234e-6
GO:0032890 regulation of organic acid transport 1.100128e-6
GO:0006651 diacylglycerol biosynthetic process 1.107074e-6
GO:0002699 positive regulation of immune effector process 2.318281e-6
GO:0014050 negative regulation of glutamate secretion 2.557911e-6
GO:0034394 protein localization at cell surface 2.668794e-6
GO:0002439 chronic inflammatory response to antigenic stimulus 6.672993e-6
GO:0032816 positive regulation of natural killer cell activation 8.364515e-6
GO:0008210 estrogen metabolic process 9.217491e-6
GO:0051707 response to other organism 9.443458e-6
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 9.510344e-6
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 9.809774e-6
GO:0006937 regulation of muscle contraction 1.009603e-5
GO:0000103 sulfate assimilation 1.044249e-5
GO:0000724 double-strand break repair via homologous recombination 1.151443e-5
GO:0006108 malate metabolic process 1.265383e-5
GO:0009617 response to bacterium 1.435492e-5
GO:0046635 positive regulation of alpha-beta T cell activation 1.495825e-5
GO:0000725 recombinational repair 1.768439e-5
GO:0001910 regulation of leukocyte mediated cytotoxicity 1.913666e-5
GO:0055119 relaxation of cardiac muscle 2.127223e-5
GO:0034754 cellular hormone metabolic process 2.180699e-5
GO:0042445 hormone metabolic process 2.233917e-5
GO:0010519 negative regulation of phospholipase activity 2.289268e-5
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 2.931994e-5
GO:0018960 4-nitrophenol metabolic process 2.932268e-5
GO:0010574 regulation of vascular endothelial growth factor production 3.045458e-5
GO:0010661 positive regulation of muscle cell apoptosis 3.501416e-5
GO:0009635 response to herbicide 3.501416e-5
GO:0006787 porphyrin-containing compound catabolic process 3.618828e-5
GO:0001887 selenium compound metabolic process 3.618828e-5
GO:0090257 regulation of muscle system process 3.664499e-5
GO:0042472 inner ear morphogenesis 3.675694e-5
GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 3.939187e-5
GO:0046600 negative regulation of centriole replication 4.179163e-5
GO:0009607 response to biotic stimulus 4.413145e-5
GO:0032496 response to lipopolysaccharide 4.469877e-5
GO:0002711 positive regulation of T cell mediated immunity 4.538283e-5
GO:0051187 cofactor catabolic process 4.564497e-5
GO:0031343 positive regulation of cell killing 4.584334e-5
GO:0034393 positive regulation of smooth muscle cell apoptosis 4.973769e-5
GO:0002697 regulation of immune effector process 5.284037e-5
GO:0042471 ear morphogenesis 5.827423e-5
GO:0003008 system process 5.845176e-5
GO:0051135 positive regulation of NK T cell activation 5.905437e-5
GO:0090007 regulation of mitotic anaphase 6.452963e-5
GO:2000381 negative regulation of mesoderm development 7.149856e-5
GO:0031341 regulation of cell killing 7.334646e-5
GO:0006942 regulation of striated muscle contraction 8.237156e-5
GO:0048660 regulation of smooth muscle cell proliferation 8.855679e-5
GO:0043491 protein kinase B signaling cascade 8.876889e-5
GO:0002237 response to molecule of bacterial origin 9.958149e-5
GO:0061338 atrioventricular node impulse conduction delay 1.000411e-4
GO:0055118 negative regulation of cardiac muscle contraction 1.019816e-4
GO:0002437 inflammatory response to antigenic stimulus 1.039075e-4
GO:0070164 negative regulation of adiponectin secretion 1.145796e-4
GO:0042489 negative regulation of odontogenesis of dentine-containing tooth 1.145796e-4
GO:0035505 positive regulation of myosin light chain kinase activity 1.145796e-4
GO:0009052 pentose-phosphate shunt, non-oxidative branch 1.160881e-4
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 1.185962e-4
GO:0007144 female meiosis I 1.262846e-4
GO:0048745 smooth muscle tissue development 1.314036e-4
GO:0002708 positive regulation of lymphocyte mediated immunity 1.353536e-4
GO:0030168 platelet activation 1.362473e-4
GO:0002703 regulation of leukocyte mediated immunity 1.364399e-4
GO:0042742 defense response to bacterium 1.395499e-4
GO:0031349 positive regulation of defense response 1.429420e-4
GO:0032425 positive regulation of mismatch repair 1.452482e-4
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 1.594613e-4
GO:2000191 regulation of fatty acid transport 1.749931e-4
GO:0046069 cGMP catabolic process 1.772395e-4
GO:0030593 neutrophil chemotaxis 1.805016e-4
GO:0051704 multi-organism process 1.823360e-4
GO:0002329 pre-B cell differentiation 1.848942e-4
GO:0010817 regulation of hormone levels 1.898943e-4
GO:0030178 negative regulation of Wnt receptor signaling pathway 1.915361e-4
GO:0046634 regulation of alpha-beta T cell activation 1.937164e-4
GO:0032700 negative regulation of interleukin-17 production 1.966546e-4
GO:0071436 sodium ion export 2.013135e-4
GO:0033152 immunoglobulin V(D)J recombination 2.021105e-4
GO:0046641 positive regulation of alpha-beta T cell proliferation 2.022984e-4
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 2.196086e-4
GO:0051984 positive regulation of chromosome segregation 2.253916e-4
GO:0032075 positive regulation of nuclease activity 2.363217e-4
GO:0035967 cellular response to topologically incorrect protein 2.489322e-4
GO:0045907 positive regulation of vasoconstriction 2.493753e-4
GO:0032185 septin cytoskeleton organization 2.505642e-4
GO:0019370 leukotriene biosynthetic process 2.658636e-4
GO:0010963 regulation of L-arginine import 2.691725e-4
GO:0032892 positive regulation of organic acid transport 2.699496e-4
GO:0002426 immunoglobulin production in mucosal tissue 2.718542e-4
GO:0010517 regulation of phospholipase activity 2.819099e-4
GO:0046456 icosanoid biosynthetic process 2.828387e-4
GO:0010575 positive regulation vascular endothelial growth factor production 2.949395e-4
GO:0007586 digestion 3.058104e-4
GO:2001054 negative regulation of mesenchymal cell apoptosis 3.086424e-4
GO:0050796 regulation of insulin secretion 3.098651e-4
GO:0061337 cardiac conduction 3.277149e-4
GO:0042446 hormone biosynthetic process 3.542119e-4
GO:0032000 positive regulation of fatty acid beta-oxidation 3.545226e-4
GO:0007614 short-term memory 3.545226e-4
GO:0030968 endoplasmic reticulum unfolded protein response 3.558758e-4
GO:0090276 regulation of peptide hormone secretion 3.664235e-4
GO:0021935 cerebellar granule cell precursor tangential migration 3.666509e-4
GO:0006104 succinyl-CoA metabolic process 3.666509e-4
GO:0051645 Golgi localization 3.693632e-4
GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis 3.698287e-4
GO:0031023 microtubule organizing center organization 3.763329e-4
GO:0055114 oxidation-reduction process 4.157818e-4
GO:2000054 negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 4.284444e-4
GO:0006636 unsaturated fatty acid biosynthetic process 4.411179e-4
GO:0048662 negative regulation of smooth muscle cell proliferation 4.552604e-4
GO:0006749 glutathione metabolic process 4.709202e-4
GO:2000078 positive regulation of type B pancreatic cell development 4.725708e-4
GO:0051955 regulation of amino acid transport 4.778271e-4
GO:0006463 steroid hormone receptor complex assembly 4.919762e-4
GO:0080134 regulation of response to stress 5.068166e-4
GO:0070861 regulation of protein exit from endoplasmic reticulum 5.166637e-4
GO:0071955 recycling endosome to Golgi transport 5.166637e-4
GO:0034499 late endosome to Golgi transport 5.166637e-4
GO:0031129 inductive cell-cell signaling 5.166637e-4
GO:0001736 establishment of planar polarity 5.180455e-4
GO:0045932 negative regulation of muscle contraction 5.215746e-4
GO:0006750 glutathione biosynthetic process 5.257440e-4
GO:0001879 detection of yeast 5.467799e-4
GO:0015721 bile acid and bile salt transport 5.538792e-4
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5.713107e-4
GO:0044237 cellular metabolic process 5.955096e-4
GO:0055117 regulation of cardiac muscle contraction 6.138706e-4
GO:0043277 apoptotic cell clearance 6.158505e-4
GO:0031947 negative regulation of glucocorticoid biosynthetic process 6.450481e-4
GO:0019693 ribose phosphate metabolic process 6.632570e-4
GO:0032729 positive regulation of interferon-gamma production 7.380179e-4
GO:0034391 regulation of smooth muscle cell apoptosis 7.820227e-4
GO:0032784 regulation of transcription elongation, DNA-dependent 8.129648e-4
GO:0002791 regulation of peptide secretion 8.345084e-4
GO:0016045 detection of bacterium 8.587652e-4
GO:0032872 regulation of stress-activated MAPK cascade 8.648059e-4
GO:0007164 establishment of tissue polarity 8.648059e-4
GO:0001672 regulation of chromatin assembly or disassembly 8.765866e-4
GO:0002528 regulation of vascular permeability involved in acute inflammatory response 8.828576e-4
GO:0050996 positive regulation of lipid catabolic process 8.952103e-4
GO:0006952 defense response 8.989915e-4
GO:0033151 V(D)J recombination 9.004824e-4
GO:0051241 negative regulation of multicellular organismal process 9.010642e-4
GO:0010983 positive regulation of high-density lipoprotein particle clearance 9.348516e-4
GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific 9.348516e-4
GO:0047484 regulation of response to osmotic stress 9.388135e-4
GO:0006691 leukotriene metabolic process 9.390831e-4
GO:0006393 termination of mitochondrial transcription 9.511596e-4
GO:0045988 negative regulation of striated muscle contraction 1.018890e-3
GO:0061181 regulation of chondrocyte development 1.065444e-3
GO:0001556 oocyte maturation 1.086605e-3
GO:0010669 epithelial structure maintenance 1.103300e-3
GO:0048016 inositol phosphate-mediated signaling 1.131669e-3
GO:0032785 negative regulation of transcription elongation, DNA-dependent 1.159485e-3
GO:0032787 monocarboxylic acid metabolic process 1.161667e-3
GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter 1.221261e-3
GO:0009217 purine deoxyribonucleoside triphosphate catabolic process 1.221261e-3
GO:0002544 chronic inflammatory response 1.233262e-3
GO:0006940 regulation of smooth muscle contraction 1.246508e-3
GO:0032874 positive regulation of stress-activated MAPK cascade 1.250657e-3
GO:0002886 regulation of myeloid leukocyte mediated immunity 1.258471e-3
GO:0010613 positive regulation of cardiac muscle hypertrophy 1.265882e-3
GO:0048839 inner ear development 1.277117e-3
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway 1.278258e-3
GO:0002709 regulation of T cell mediated immunity 1.320924e-3
GO:0051179 localization 1.323490e-3
GO:0006288 base-excision repair, DNA ligation 1.337795e-3
GO:0006014 D-ribose metabolic process 1.354261e-3
GO:0060043 regulation of cardiac muscle cell proliferation 1.416453e-3
GO:0090075 relaxation of muscle 1.419033e-3
GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger 1.444691e-3
GO:0060420 regulation of heart growth 1.498501e-3
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 1.512522e-3
GO:0045401 positive regulation of interleukin-3 biosynthetic process 1.512522e-3
GO:0051131 chaperone-mediated protein complex assembly 1.526619e-3
GO:0006082 organic acid metabolic process 1.533747e-3
GO:0055021 regulation of cardiac muscle tissue growth 1.540425e-3
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1.558177e-3
GO:0014743 regulation of muscle hypertrophy 1.576016e-3
GO:0010863 positive regulation of phospholipase C activity 1.722618e-3
GO:0009264 deoxyribonucleotide catabolic process 1.735045e-3
GO:0008154 actin polymerization or depolymerization 1.742374e-3
GO:0050896 response to stimulus 1.775518e-3
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 1.781569e-3
GO:0009125 nucleoside monophosphate catabolic process 1.787267e-3
GO:0033280 response to vitamin D 1.807734e-3
GO:0007202 activation of phospholipase C activity 1.843337e-3
GO:0006084 acetyl-CoA metabolic process 1.902698e-3
GO:0046339 diacylglycerol metabolic process 1.919427e-3
GO:0015701 bicarbonate transport 1.919427e-3
GO:0071477 cellular hypotonic salinity response 1.954682e-3
GO:0032308 positive regulation of prostaglandin secretion 1.964347e-3
GO:0046599 regulation of centriole replication 1.964347e-3
GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 1.964347e-3
GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 2.005663e-3
GO:0034626 fatty acid elongation, polyunsaturated fatty acid 2.010003e-3
GO:0031929 TOR signaling cascade 2.010003e-3
GO:0006986 response to unfolded protein 2.029529e-3
GO:0045588 positive regulation of gamma-delta T cell differentiation 2.032688e-3
GO:0007157 heterophilic cell-cell adhesion 2.033319e-3
GO:0021589 cerebellum structural organization 2.084048e-3
GO:0045947 negative regulation of translational initiation 2.124912e-3
GO:0070163 regulation of adiponectin secretion 2.141842e-3
GO:0010986 positive regulation of lipoprotein particle clearance 2.141842e-3
GO:0007196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway 2.141842e-3
GO:0046851 negative regulation of bone remodeling 2.179363e-3
GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 2.190076e-3
GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 2.215881e-3
GO:0048304 positive regulation of isotype switching to IgG isotypes 2.233648e-3
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 2.363964e-3
GO:0002706 regulation of lymphocyte mediated immunity 2.366051e-3
GO:0001819 positive regulation of cytokine production 2.399174e-3
GO:0002639 positive regulation of immunoglobulin production 2.400735e-3
GO:0010501 RNA secondary structure unwinding 2.415827e-3
GO:0009204 deoxyribonucleoside triphosphate catabolic process 2.422310e-3
GO:2000053 regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 2.442690e-3
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 2.442690e-3
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 2.501205e-3
GO:0046640 regulation of alpha-beta T cell proliferation 2.512934e-3
GO:0006690 icosanoid metabolic process 2.523251e-3
GO:0050729 positive regulation of inflammatory response 2.648355e-3
GO:0042180 cellular ketone metabolic process 2.677008e-3
GO:0019752 carboxylic acid metabolic process 2.678231e-3
GO:0032660 regulation of interleukin-17 production 2.782516e-3
GO:0033299 secretion of lysosomal enzymes 2.798718e-3
GO:0006310 DNA recombination 2.798898e-3
GO:0043583 ear development 2.799957e-3
GO:0007204 elevation of cytosolic calcium ion concentration 2.836122e-3
GO:0006670 sphingosine metabolic process 2.859889e-3
GO:0043506 regulation of JUN kinase activity 2.870751e-3
GO:0000003 reproduction 2.891203e-3
GO:0042167 heme catabolic process 2.946560e-3
GO:0002678 positive regulation of chronic inflammatory response 2.949487e-3
GO:0001738 morphogenesis of a polarized epithelium 2.987559e-3
GO:0030901 midbrain development 3.015333e-3
GO:0006686 sphingomyelin biosynthetic process 3.047311e-3
GO:0060441 epithelial tube branching involved in lung morphogenesis 3.057333e-3
GO:0035567 non-canonical Wnt receptor signaling pathway 3.068947e-3
GO:0014054 positive regulation of gamma-aminobutyric acid secretion 3.116662e-3
GO:0002026 regulation of the force of heart contraction 3.128118e-3
GO:0006672 ceramide metabolic process 3.159441e-3
GO:0032069 regulation of nuclease activity 3.231213e-3
GO:0051094 positive regulation of developmental process 3.376769e-3
GO:0045860 positive regulation of protein kinase activity 3.382506e-3
GO:0046068 cGMP metabolic process 3.403980e-3
GO:0042832 defense response to protozoan 3.406029e-3
GO:0003416 endochondral bone growth 3.406029e-3
GO:0031581 hemidesmosome assembly 3.451459e-3
GO:0009214 cyclic nucleotide catabolic process 3.469559e-3
GO:0060662 salivary gland cavitation 3.470262e-3
GO:0007218 neuropeptide signaling pathway 3.481101e-3
GO:0003013 circulatory system process 3.521640e-3
GO:0051967 negative regulation of synaptic transmission, glutamatergic 3.533003e-3
GO:0050880 regulation of blood vessel size 3.545277e-3
GO:0060032 notochord regression 3.551712e-3
GO:0003018 vascular process in circulatory system 3.594666e-3
GO:0031347 regulation of defense response 3.614174e-3
GO:0042129 regulation of T cell proliferation 3.622377e-3
GO:0035150 regulation of tube size 3.627076e-3
GO:0001657 ureteric bud development 3.666441e-3
GO:0050882 voluntary musculoskeletal movement 3.675462e-3
GO:0032320 positive regulation of Ras GTPase activity 3.827390e-3
GO:0045657 positive regulation of monocyte differentiation 3.852819e-3
GO:0033574 response to testosterone stimulus 3.859454e-3
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 3.912604e-3
GO:0042269 regulation of natural killer cell mediated cytotoxicity 3.912604e-3
GO:0006099 tricarboxylic acid cycle 3.922363e-3
GO:0002676 regulation of chronic inflammatory response 4.021886e-3
GO:0009615 response to virus 4.038256e-3
GO:0048302 regulation of isotype switching to IgG isotypes 4.101536e-3
GO:0070302 regulation of stress-activated protein kinase signaling cascade 4.151799e-3
GO:0001817 regulation of cytokine production 4.154925e-3
GO:0050702 interleukin-1 beta secretion 4.180530e-3
GO:0043471 regulation of cellular carbohydrate catabolic process 4.190467e-3
GO:0009268 response to pH 4.199965e-3
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 4.265723e-3
GO:0051297 centrosome organization 4.296019e-3
GO:0034113 heterotypic cell-cell adhesion 4.375914e-3
GO:0031340 positive regulation of vesicle fusion 4.567787e-3
GO:0030098 lymphocyte differentiation 4.653361e-3
GO:0033674 positive regulation of kinase activity 4.727008e-3
GO:0030033 microvillus assembly 4.733200e-3
GO:0032611 interleukin-1 beta production 4.733200e-3
GO:0050794 regulation of cellular process 4.907788e-3
GO:0002837 regulation of immune response to tumor cell 4.928653e-3
GO:0010269 response to selenium ion 4.936731e-3
GO:0071472 cellular response to salt stress 5.003844e-3
GO:0001865 NK T cell differentiation 5.003844e-3
GO:0032633 interleukin-4 production 5.003844e-3
GO:0002821 positive regulation of adaptive immune response 5.006843e-3
GO:0042403 thyroid hormone metabolic process 5.082005e-3
GO:0002248 connective tissue replacement involved in inflammatory response wound healing 5.188166e-3
GO:0055091 phospholipid homeostasis 5.292038e-3
GO:0035966 response to topologically incorrect protein 5.292417e-3
GO:0002637 regulation of immunoglobulin production 5.292417e-3
GO:0045830 positive regulation of isotype switching 5.299679e-3
GO:0014048 regulation of glutamate secretion 5.299679e-3
GO:0032793 positive regulation of CREB transcription factor activity 5.374657e-3
GO:0008152 metabolic process 5.413713e-3
GO:0045577 regulation of B cell differentiation 5.422904e-3
GO:2000009 negative regulation of protein localization at cell surface 5.475087e-3
GO:0019098 reproductive behavior 5.525349e-3
GO:0032649 regulation of interferon-gamma production 5.547644e-3
GO:0045454 cell redox homeostasis 5.582093e-3
GO:0016310 phosphorylation 5.684377e-3
GO:0008610 lipid biosynthetic process 5.727777e-3
GO:0043300 regulation of leukocyte degranulation 5.757519e-3
GO:0051103 DNA ligation involved in DNA repair 5.815980e-3
GO:0010464 regulation of mesenchymal cell proliferation 5.852696e-3
GO:0051017 actin filament bundle assembly 5.853364e-3
GO:0016539 intein-mediated protein splicing 5.859690e-3
GO:0050877 neurological system process 5.861931e-3
GO:0016575 histone deacetylation 5.948448e-3
GO:0070602 regulation of centromeric sister chromatid cohesion 5.990616e-3
GO:0050830 defense response to Gram-positive bacterium 6.047359e-3
GO:0031399 regulation of protein modification process 6.135672e-3
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 6.145151e-3
GO:0065008 regulation of biological quality 6.153505e-3
GO:0046519 sphingoid metabolic process 6.170739e-3
GO:0051983 regulation of chromosome segregation 6.194113e-3
GO:0031503 protein complex localization 6.349913e-3
GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport 6.349913e-3
GO:0001562 response to protozoan 6.415250e-3
GO:0023057 negative regulation of signaling 6.416088e-3
GO:0010518 positive regulation of phospholipase activity 6.436669e-3
GO:0006776 vitamin A metabolic process 6.503223e-3
GO:0022414 reproductive process 6.601799e-3
GO:0072560 type B pancreatic cell maturation 6.648758e-3
GO:0055024 regulation of cardiac muscle tissue development 6.696196e-3
GO:0015870 acetylcholine transport 6.699923e-3
GO:0042221 response to chemical stimulus 6.733623e-3
GO:0046356 acetyl-CoA catabolic process 6.768245e-3
GO:0032754 positive regulation of interleukin-5 production 6.779079e-3
GO:0032370 positive regulation of lipid transport 6.786659e-3
GO:0006629 lipid metabolic process 6.792736e-3
GO:2000193 positive regulation of fatty acid transport 6.834391e-3
GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 6.834391e-3
GO:0010648 negative regulation of cell communication 6.960536e-3
GO:0002456 T cell mediated immunity 6.982590e-3
GO:0006633 fatty acid biosynthetic process 7.105255e-3
GO:0034976 response to endoplasmic reticulum stress 7.177797e-3
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 7.302731e-3
GO:0045410 positive regulation of interleukin-6 biosynthetic process 7.465942e-3
GO:0003341 cilium movement 7.465942e-3
GO:0032268 regulation of cellular protein metabolic process 7.486808e-3
GO:0046496 nicotinamide nucleotide metabolic process 7.514976e-3
GO:0035414 negative regulation of catenin import into nucleus 7.563117e-3
GO:0043507 positive regulation of JUN kinase activity 7.782592e-3
GO:2000384 negative regulation of ectoderm development 7.851698e-3
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 7.851698e-3
GO:0090161 Golgi ribbon formation 7.851698e-3
GO:0042574 retinal metabolic process 7.855703e-3
GO:0006206 pyrimidine base metabolic process 7.907914e-3
GO:0090103 cochlea morphogenesis 7.915619e-3
GO:0002521 leukocyte differentiation 8.063260e-3
GO:0051239 regulation of multicellular organismal process 8.083678e-3
GO:0010611 regulation of cardiac muscle hypertrophy 8.105145e-3
GO:0008347 glial cell migration 8.150987e-3
GO:0045088 regulation of innate immune response 8.157309e-3
GO:0015718 monocarboxylic acid transport 8.228115e-3
GO:0030423 targeting of mRNA for destruction involved in RNA interference 8.269599e-3
GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine 8.269599e-3
GO:0043406 positive regulation of MAP kinase activity 8.312715e-3
GO:0051347 positive regulation of transferase activity 8.325977e-3
GO:0048562 embryonic organ morphogenesis 8.369840e-3
GO:0009109 coenzyme catabolic process 8.404999e-3
GO:0002891 positive regulation of immunoglobulin mediated immune response 8.404999e-3
GO:0031998 regulation of fatty acid beta-oxidation 8.424818e-3
GO:0032736 positive regulation of interleukin-13 production 8.438929e-3
GO:0043043 peptide biosynthetic process 8.464120e-3
GO:0050855 regulation of B cell receptor signaling pathway 8.465033e-3
GO:0007340 acrosome reaction 8.465033e-3
GO:0006821 chloride transport 8.815842e-3
GO:0045911 positive regulation of DNA recombination 8.873180e-3
GO:0045162 clustering of voltage-gated sodium channels 8.995544e-3
GO:0006704 glucocorticoid biosynthetic process 9.053342e-3
GO:0045779 negative regulation of bone resorption 9.053342e-3
GO:0033043 regulation of organelle organization 9.117378e-3
GO:0009595 detection of biotic stimulus 9.370091e-3
GO:0060044 negative regulation of cardiac muscle cell proliferation 9.446261e-3
GO:0050852 T cell receptor signaling pathway 9.569353e-3
GO:0070327 thyroid hormone transport 9.577646e-3
GO:0045089 positive regulation of innate immune response 9.584161e-3
GO:0051054 positive regulation of DNA metabolic process 9.589910e-3
GO:0007417 central nervous system development 9.708856e-3
GO:0019368 fatty acid elongation, unsaturated fatty acid 9.795300e-3
GO:0043089 positive regulation of Cdc42 GTPase activity 9.967914e-3
GO:0032849 positive regulation of cellular pH reduction 1.012577e-2
GO:0060155 platelet dense granule organization 1.012577e-2
GO:0071476 cellular hypotonic response 1.024271e-2
GO:0090179 planar cell polarity pathway involved in neural tube closure 1.037944e-2
GO:0002385 mucosal immune response 1.051095e-2
GO:0045597 positive regulation of cell differentiation 1.054158e-2
GO:0009060 aerobic respiration 1.056748e-2
GO:0006950 response to stress 1.066307e-2
GO:0001960 negative regulation of cytokine-mediated signaling pathway 1.067767e-2
GO:0035725 sodium ion transmembrane transport 1.090094e-2
GO:0030217 T cell differentiation 1.105505e-2
GO:0090244 Wnt receptor signaling pathway involved in somitogenesis 1.113986e-2
GO:0015670 carbon dioxide transport 1.113986e-2
GO:0043366 beta selection 1.113986e-2
GO:2000727 positive regulation of cardiac muscle cell differentiation 1.119399e-2
GO:0030041 actin filament polymerization 1.119399e-2
GO:0032506 cytokinetic process 1.120862e-2
GO:0042311 vasodilation 1.132918e-2
GO:0002839 positive regulation of immune response to tumor cell 1.133633e-2
GO:0019400 alditol metabolic process 1.146308e-2
GO:0001523 retinoid metabolic process 1.146308e-2
GO:2000383 regulation of ectoderm development 1.159650e-2
GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry 1.159650e-2
GO:0007418 ventral midline development 1.159650e-2
GO:0016476 regulation of embryonic cell shape 1.159650e-2
GO:0015698 inorganic anion transport 1.163306e-2
GO:0008016 regulation of heart contraction 1.164461e-2
GO:0051099 positive regulation of binding 1.185594e-2
GO:0048519 negative regulation of biological process 1.196810e-2
GO:0046883 regulation of hormone secretion 1.204461e-2
GO:0048295 positive regulation of isotype switching to IgE isotypes 1.215177e-2
GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway 1.215177e-2
GO:0031953 negative regulation of protein autophosphorylation 1.215218e-2
GO:0050701 interleukin-1 secretion 1.222100e-2
GO:0045621 positive regulation of lymphocyte differentiation 1.225659e-2
GO:0034104 negative regulation of tissue remodeling 1.227356e-2
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 1.227356e-2
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1.230172e-2
GO:0030804 positive regulation of cyclic nucleotide biosynthetic process 1.236509e-2
GO:0045668 negative regulation of osteoblast differentiation 1.237206e-2
GO:0045582 positive regulation of T cell differentiation 1.247832e-2
GO:0006417 regulation of translation 1.259469e-2
GO:0006081 cellular aldehyde metabolic process 1.261136e-2
GO:0042102 positive regulation of T cell proliferation 1.261452e-2
GO:0031342 negative regulation of cell killing 1.273850e-2
GO:0002251 organ or tissue specific immune response 1.290731e-2
GO:0046427 positive regulation of JAK-STAT cascade 1.297679e-2
GO:0090231 regulation of spindle checkpoint 1.302640e-2
GO:0009649 entrainment of circadian clock 1.302640e-2
GO:0002698 negative regulation of immune effector process 1.302828e-2
GO:0035802 adrenal cortex formation 1.305995e-2
GO:0019852 L-ascorbic acid metabolic process 1.306558e-2
GO:0070980 biphenyl catabolic process 1.313449e-2
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.326423e-2
GO:0046321 positive regulation of fatty acid oxidation 1.327734e-2
GO:2000725 regulation of cardiac muscle cell differentiation 1.328441e-2
GO:0032612 interleukin-1 production 1.337104e-2
GO:0051052 regulation of DNA metabolic process 1.344409e-2
GO:0016578 histone deubiquitination 1.344623e-2
GO:0097113 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering 1.344623e-2
GO:0001915 negative regulation of T cell mediated cytotoxicity 1.356504e-2
GO:0046328 regulation of JNK cascade 1.360682e-2
GO:0060968 regulation of gene silencing 1.380512e-2
GO:0042572 retinol metabolic process 1.380512e-2
GO:0032609 interferon-gamma production 1.400847e-2
GO:0014052 regulation of gamma-aminobutyric acid secretion 1.400847e-2
GO:0002831 regulation of response to biotic stimulus 1.413792e-2
GO:0065007 biological regulation 1.423149e-2
GO:0042325 regulation of phosphorylation 1.423937e-2
GO:0031622 positive regulation of fever generation 1.430452e-2
GO:0034435 cholesterol esterification 1.430452e-2
GO:0010824 regulation of centrosome duplication 1.430452e-2
GO:0007605 sensory perception of sound 1.441098e-2
GO:0046186 acetaldehyde biosynthetic process 1.442182e-2
GO:0006788 heme oxidation 1.442182e-2
GO:0042487 regulation of odontogenesis of dentine-containing tooth 1.459180e-2
GO:0006987 activation of signaling protein activity involved in unfolded protein response 1.463590e-2
GO:0045428 regulation of nitric oxide biosynthetic process 1.466034e-2
GO:0045921 positive regulation of exocytosis 1.471328e-2
GO:0046685 response to arsenic-containing substance 1.484475e-2
GO:0010224 response to UV-B 1.484475e-2
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 1.484475e-2
GO:0014850 response to muscle activity 1.484475e-2
GO:0043011 myeloid dendritic cell differentiation 1.484475e-2
GO:0002833 positive regulation of response to biotic stimulus 1.490563e-2
GO:0006208 pyrimidine base catabolic process 1.495442e-2
GO:0006098 pentose-phosphate shunt 1.502306e-2
GO:0009581 detection of external stimulus 1.510635e-2
GO:0006406 mRNA export from nucleus 1.511083e-2
GO:0090273 regulation of somatostatin secretion 1.520118e-2
GO:0045956 positive regulation of calcium ion-dependent exocytosis 1.537496e-2
GO:0006766 vitamin metabolic process 1.550329e-2
GO:0006909 phagocytosis 1.566552e-2
GO:0006621 protein retention in ER lumen 1.612501e-2
GO:0043306 positive regulation of mast cell degranulation 1.613707e-2
GO:0006266 DNA ligation 1.613707e-2
GO:0042404 thyroid hormone catabolic process 1.620654e-2
GO:0050885 neuromuscular process controlling balance 1.624120e-2
GO:0085020 protein K6-linked ubiquitination 1.632692e-2
GO:0071637 regulation of monocyte chemotactic protein-1 production 1.632692e-2
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1.632692e-2