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Novel motif:69

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name:motif69_RYKNAAATC

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0097045 phosphatidylserine exposure on blood platelet 2.812123e-13
GO:0046836 glycolipid transport 5.035282e-11
GO:0051024 positive regulation of immunoglobulin secretion 1.409144e-10
GO:0032655 regulation of interleukin-12 production 2.621958e-10
GO:0007610 behavior 3.700626e-10
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 5.214721e-10
GO:0045429 positive regulation of nitric oxide biosynthetic process 1.606504e-9
GO:0050820 positive regulation of coagulation 3.005781e-9
GO:0030194 positive regulation of blood coagulation 3.555467e-9
GO:0045187 regulation of circadian sleep/wake cycle, sleep 3.997379e-9
GO:0006954 inflammatory response 5.335006e-9
GO:0006952 defense response 7.725291e-9
GO:0022410 circadian sleep/wake cycle process 8.452588e-9
GO:2000366 positive regulation of STAT protein import into nucleus 1.115811e-8
GO:0070091 glucagon secretion 1.115811e-8
GO:0018283 iron incorporation into metallo-sulfur cluster 1.275347e-8
GO:0002384 hepatic immune response 1.344987e-8
GO:0034121 regulation of toll-like receptor signaling pathway 1.476102e-8
GO:0045765 regulation of angiogenesis 1.668577e-8
GO:0042745 circadian sleep/wake cycle 1.735736e-8
GO:0051240 positive regulation of multicellular organismal process 1.757710e-8
GO:0001764 neuron migration 2.533109e-8
GO:0046851 negative regulation of bone remodeling 2.954563e-8
GO:0042752 regulation of circadian rhythm 3.813053e-8
GO:0048512 circadian behavior 5.085929e-8
GO:0007565 female pregnancy 6.314746e-8
GO:0006959 humoral immune response 6.684619e-8
GO:0051239 regulation of multicellular organismal process 7.932214e-8
GO:0051023 regulation of immunoglobulin secretion 9.251197e-8
GO:0060124 positive regulation of growth hormone secretion 9.751988e-8
GO:0001781 neutrophil apoptosis 9.808942e-8
GO:0032695 negative regulation of interleukin-12 production 9.836226e-8
GO:0002543 activation of blood coagulation via clotting cascade 1.050573e-7
GO:0006955 immune response 1.155558e-7
GO:0009408 response to heat 1.198794e-7
GO:0046850 regulation of bone remodeling 1.199731e-7
GO:0018065 protein-cofactor linkage 1.563636e-7
GO:0010757 negative regulation of plasminogen activation 1.956321e-7
GO:0009597 detection of virus 2.155933e-7
GO:0010755 regulation of plasminogen activation 3.112024e-7
GO:0060123 regulation of growth hormone secretion 3.440450e-7
GO:0034104 negative regulation of tissue remodeling 4.116830e-7
GO:0051223 regulation of protein transport 4.369569e-7
GO:0001776 leukocyte homeostasis 4.810310e-7
GO:0032101 regulation of response to external stimulus 4.842653e-7
GO:0043066 negative regulation of apoptosis 5.224726e-7
GO:0051382 kinetochore assembly 5.422679e-7
GO:0060548 negative regulation of cell death 5.564309e-7
GO:2000026 regulation of multicellular organismal development 5.678368e-7
GO:0061041 regulation of wound healing 5.766075e-7
GO:0071034 CUT catabolic process 6.221180e-7
GO:0070489 T cell aggregation 6.221180e-7
GO:0045727 positive regulation of translation 7.062163e-7
GO:0014074 response to purine-containing compound 7.485428e-7
GO:0050818 regulation of coagulation 7.518890e-7
GO:0031000 response to caffeine 7.588771e-7
GO:0032755 positive regulation of interleukin-6 production 7.608965e-7
GO:0050709 negative regulation of protein secretion 7.639537e-7
GO:0032494 response to peptidoglycan 7.762132e-7
GO:0045779 negative regulation of bone resorption 8.219959e-7
GO:0007622 rhythmic behavior 8.219959e-7
GO:0043069 negative regulation of programmed cell death 8.290621e-7
GO:0045428 regulation of nitric oxide biosynthetic process 9.503591e-7
GO:0010722 regulation of ferrochelatase activity 9.580940e-7
GO:0050883 musculoskeletal movement, spinal reflex action 9.589726e-7
GO:0051383 kinetochore organization 1.307087e-6
GO:0051704 multi-organism process 1.322694e-6
GO:0007619 courtship behavior 1.375981e-6
GO:0045321 leukocyte activation 1.407093e-6
GO:0071347 cellular response to interleukin-1 1.427442e-6
GO:0001780 neutrophil homeostasis 1.458841e-6
GO:0045124 regulation of bone resorption 1.645007e-6
GO:0034508 centromere complex assembly 1.663094e-6
GO:0032675 regulation of interleukin-6 production 1.718553e-6
GO:0001819 positive regulation of cytokine production 1.774973e-6
GO:0002260 lymphocyte homeostasis 1.812019e-6
GO:0070555 response to interleukin-1 1.832543e-6
GO:0002688 regulation of leukocyte chemotaxis 1.932274e-6
GO:0018352 protein-pyridoxal-5-phosphate linkage 2.030715e-6
GO:0070102 interleukin-6-mediated signaling pathway 2.075160e-6
GO:0030193 regulation of blood coagulation 2.280707e-6
GO:0007566 embryo implantation 2.364092e-6
GO:0032680 regulation of tumor necrosis factor production 2.781678e-6
GO:0000236 mitotic prometaphase 2.879057e-6
GO:0009595 detection of biotic stimulus 2.975408e-6
GO:0035520 monoubiquitinated protein deubiquitination 3.064073e-6
GO:0070201 regulation of establishment of protein localization 3.202798e-6
GO:0002694 regulation of leukocyte activation 3.555108e-6
GO:0002690 positive regulation of leukocyte chemotaxis 3.645812e-6
GO:0071593 lymphocyte aggregation 3.856059e-6
GO:0000165 MAPKKK cascade 3.982353e-6
GO:0007252 I-kappaB phosphorylation 4.162175e-6
GO:0050865 regulation of cell activation 4.260412e-6
GO:0045079 negative regulation of chemokine biosynthetic process 4.271990e-6
GO:0046649 lymphocyte activation 4.537452e-6
GO:0051249 regulation of lymphocyte activation 4.649411e-6
GO:0032386 regulation of intracellular transport 4.824546e-6
GO:0002684 positive regulation of immune system process 5.382560e-6
GO:0035690 cellular response to drug 5.494659e-6
GO:0048520 positive regulation of behavior 5.899357e-6
GO:0035556 intracellular signal transduction 6.199605e-6
GO:0051241 negative regulation of multicellular organismal process 6.736662e-6
GO:0051971 positive regulation of transmission of nerve impulse 6.808885e-6
GO:0002262 myeloid cell homeostasis 6.941336e-6
GO:0048305 immunoglobulin secretion 7.393072e-6
GO:0043502 regulation of muscle adaptation 7.596359e-6
GO:0033160 positive regulation of protein import into nucleus, translocation 7.606531e-6
GO:0046822 regulation of nucleocytoplasmic transport 7.753712e-6
GO:0051701 interaction with host 8.049967e-6
GO:0070375 BMK cascade 8.084862e-6
GO:0010466 negative regulation of peptidase activity 8.139283e-6
GO:0071354 cellular response to interleukin-6 8.384777e-6
GO:0006916 anti-apoptosis 8.454358e-6
GO:0001817 regulation of cytokine production 8.553827e-6
GO:0071675 regulation of mononuclear cell migration 8.620983e-6
GO:0046545 development of primary female sexual characteristics 8.895327e-6
GO:0035093 spermatogenesis, exchange of chromosomal proteins 9.083457e-6
GO:0001782 B cell homeostasis 9.281239e-6
GO:0032388 positive regulation of intracellular transport 1.000012e-5
GO:0048511 rhythmic process 1.037429e-5
GO:0002376 immune system process 1.065757e-5
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 1.106646e-5
GO:0046651 lymphocyte proliferation 1.112904e-5
GO:0010751 negative regulation of nitric oxide mediated signal transduction 1.150797e-5
GO:0043652 engulfment of apoptotic cell 1.150797e-5
GO:0010754 negative regulation of cGMP-mediated signaling 1.150797e-5
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 1.150797e-5
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.150797e-5
GO:0002548 monocyte chemotaxis 1.178864e-5
GO:0006511 ubiquitin-dependent protein catabolic process 1.187183e-5
GO:0034123 positive regulation of toll-like receptor signaling pathway 1.247919e-5
GO:0032880 regulation of protein localization 1.274843e-5
GO:0031296 B cell costimulation 1.324952e-5
GO:0042307 positive regulation of protein import into nucleus 1.329263e-5
GO:0042270 protection from natural killer cell mediated cytotoxicity 1.358757e-5
GO:0010955 negative regulation of protein processing 1.454433e-5
GO:0055117 regulation of cardiac muscle contraction 1.499456e-5
GO:0042035 regulation of cytokine biosynthetic process 1.516459e-5
GO:0046716 muscle cell homeostasis 1.521619e-5
GO:0019941 modification-dependent protein catabolic process 1.666617e-5
GO:0002687 positive regulation of leukocyte migration 1.703989e-5
GO:0052548 regulation of endopeptidase activity 1.795144e-5
GO:0030595 leukocyte chemotaxis 1.815446e-5
GO:0002685 regulation of leukocyte migration 1.880536e-5
GO:0031646 positive regulation of neurological system process 1.948234e-5
GO:0050877 neurological system process 1.985079e-5
GO:0050710 negative regulation of cytokine secretion 2.016505e-5
GO:0042110 T cell activation 2.033594e-5
GO:0051094 positive regulation of developmental process 2.081599e-5
GO:0010759 positive regulation of macrophage chemotaxis 2.133936e-5
GO:0032230 positive regulation of synaptic transmission, GABAergic 2.152357e-5
GO:0006915 apoptosis 2.180654e-5
GO:0032224 positive regulation of synaptic transmission, cholinergic 2.513340e-5
GO:0043170 macromolecule metabolic process 2.558885e-5
GO:0009057 macromolecule catabolic process 2.583476e-5
GO:0097035 regulation of membrane lipid distribution 2.689395e-5
GO:0032966 negative regulation of collagen biosynthetic process 2.855987e-5
GO:0006119 oxidative phosphorylation 2.913644e-5
GO:0043129 surfactant homeostasis 2.968552e-5
GO:0043154 negative regulation of caspase activity 2.973828e-5
GO:0070661 leukocyte proliferation 2.976755e-5
GO:0031349 positive regulation of defense response 3.016809e-5
GO:0016525 negative regulation of angiogenesis 3.031077e-5
GO:0046824 positive regulation of nucleocytoplasmic transport 3.095446e-5
GO:0014739 positive regulation of muscle hyperplasia 3.159498e-5
GO:0043632 modification-dependent macromolecule catabolic process 3.174572e-5
GO:0000296 spermine transport 3.175681e-5
GO:0002218 activation of innate immune response 3.281056e-5
GO:0033157 regulation of intracellular protein transport 3.304446e-5
GO:0048518 positive regulation of biological process 3.313405e-5
GO:0042534 regulation of tumor necrosis factor biosynthetic process 3.344089e-5
GO:0048685 negative regulation of collateral sprouting of intact axon in response to injury 3.450804e-5
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 3.468418e-5
GO:0043201 response to leucine 3.476888e-5
GO:0006540 glutamate decarboxylation to succinate 3.487444e-5
GO:0010758 regulation of macrophage chemotaxis 3.487789e-5
GO:0045073 regulation of chemokine biosynthetic process 3.554610e-5
GO:0045137 development of primary sexual characteristics 3.564930e-5
GO:0050795 regulation of behavior 3.586527e-5
GO:0046660 female sex differentiation 3.893339e-5
GO:0010647 positive regulation of cell communication 3.990118e-5
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 4.073454e-5
GO:0032103 positive regulation of response to external stimulus 4.088970e-5
GO:0007009 plasma membrane organization 4.148344e-5
GO:2000112 regulation of cellular macromolecule biosynthetic process 4.174758e-5
GO:0023056 positive regulation of signaling 4.240159e-5
GO:0046834 lipid phosphorylation 4.269896e-5
GO:0030334 regulation of cell migration 4.351547e-5
GO:0002252 immune effector process 4.379018e-5
GO:0044265 cellular macromolecule catabolic process 4.397167e-5
GO:0032943 mononuclear cell proliferation 4.485019e-5
GO:0051932 synaptic transmission, GABAergic 4.560850e-5
GO:0051093 negative regulation of developmental process 4.712026e-5
GO:0007186 G-protein coupled receptor protein signaling pathway 4.720209e-5
GO:0002675 positive regulation of acute inflammatory response 4.874689e-5
GO:0042306 regulation of protein import into nucleus 4.903544e-5
GO:0021869 forebrain ventricular zone progenitor cell division 4.999589e-5
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 5.009104e-5
GO:0010468 regulation of gene expression 5.053236e-5
GO:0048584 positive regulation of response to stimulus 5.059477e-5
GO:0046854 phosphatidylinositol phosphorylation 5.184370e-5
GO:0009065 glutamine family amino acid catabolic process 5.343625e-5
GO:0009611 response to wounding 5.354440e-5
GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation 5.383775e-5
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway 5.383775e-5
GO:0007371 ventral midline determination 5.383775e-5
GO:0060248 detection of cell density by contact stimulus involved in contact inhibition 5.383775e-5
GO:0010574 regulation of vascular endothelial growth factor production 5.417950e-5
GO:0051603 proteolysis involved in cellular protein catabolic process 5.510787e-5
GO:0050884 neuromuscular process controlling posture 5.769828e-5
GO:0010766 negative regulation of sodium ion transport 5.769828e-5
GO:0060255 regulation of macromolecule metabolic process 5.865664e-5
GO:0033689 negative regulation of osteoblast proliferation 5.878483e-5
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 6.138585e-5
GO:0007270 neuron-neuron synaptic transmission 6.213780e-5
GO:0034764 positive regulation of transmembrane transport 6.321506e-5
GO:0090316 positive regulation of intracellular protein transport 6.334452e-5
GO:2000191 regulation of fatty acid transport 6.352660e-5
GO:0048634 regulation of muscle organ development 6.465645e-5
GO:0021795 cerebral cortex cell migration 6.510341e-5
GO:0012501 programmed cell death 6.668125e-5
GO:0007623 circadian rhythm 6.889305e-5
GO:0016049 cell growth 6.922347e-5
GO:0048732 gland development 6.926775e-5
GO:0044257 cellular protein catabolic process 7.060173e-5
GO:0002634 regulation of germinal center formation 7.383434e-5
GO:0008585 female gonad development 7.432995e-5
GO:0046903 secretion 7.444744e-5
GO:0030163 protein catabolic process 7.461304e-5
GO:0009266 response to temperature stimulus 7.585227e-5
GO:0060326 cell chemotaxis 8.017103e-5
GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 8.434644e-5
GO:0048522 positive regulation of cellular process 8.592198e-5
GO:0019222 regulation of metabolic process 8.739281e-5
GO:0006911 phagocytosis, engulfment 8.792345e-5
GO:0032845 negative regulation of homeostatic process 8.939932e-5
GO:0070995 NADPH oxidation 9.069722e-5
GO:0019230 proprioception 9.069722e-5
GO:0010941 regulation of cell death 9.089884e-5
GO:0071843 cellular component biogenesis at cellular level 9.107045e-5
GO:0060249 anatomical structure homeostasis 9.184821e-5
GO:0070647 protein modification by small protein conjugation or removal 9.302391e-5
GO:0031326 regulation of cellular biosynthetic process 9.303534e-5
GO:0042113 B cell activation 9.607149e-5
GO:0071504 cellular response to heparin 9.640378e-5
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 9.666126e-5
GO:0071622 regulation of granulocyte chemotaxis 1.001726e-4
GO:0050793 regulation of developmental process 1.005039e-4
GO:0051346 negative regulation of hydrolase activity 1.016512e-4
GO:0009581 detection of external stimulus 1.041869e-4
GO:0034110 regulation of homotypic cell-cell adhesion 1.052538e-4
GO:0080090 regulation of primary metabolic process 1.054214e-4
GO:0008406 gonad development 1.055847e-4
GO:0051224 negative regulation of protein transport 1.069837e-4
GO:0051180 vitamin transport 1.072319e-4
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 1.092283e-4
GO:0044003 modification by symbiont of host morphology or physiology 1.106091e-4
GO:0001561 fatty acid alpha-oxidation 1.107782e-4
GO:0046184 aldehyde biosynthetic process 1.120853e-4
GO:0090331 negative regulation of platelet aggregation 1.128721e-4
GO:0061110 dense core granule biogenesis 1.128721e-4
GO:0042628 mating plug formation 1.128721e-4
GO:0061108 seminal vesicle epithelium development 1.128721e-4
GO:0042493 response to drug 1.150398e-4
GO:0046883 regulation of hormone secretion 1.159504e-4
GO:0045667 regulation of osteoblast differentiation 1.173628e-4
GO:0050708 regulation of protein secretion 1.202882e-4
GO:0061039 ovum-producing ovary development 1.206230e-4
GO:0046620 regulation of organ growth 1.212611e-4
GO:0070613 regulation of protein processing 1.273634e-4
GO:0046485 ether lipid metabolic process 1.281264e-4
GO:0046618 drug export 1.288441e-4
GO:0009889 regulation of biosynthetic process 1.312605e-4
GO:0009617 response to bacterium 1.339312e-4
GO:0010038 response to metal ion 1.359592e-4
GO:0016226 iron-sulfur cluster assembly 1.366966e-4
GO:0010561 negative regulation of glycoprotein biosynthetic process 1.368155e-4
GO:0031323 regulation of cellular metabolic process 1.371390e-4
GO:0022602 ovulation cycle process 1.391570e-4
GO:0060284 regulation of cell development 1.394261e-4
GO:0009607 response to biotic stimulus 1.396381e-4
GO:0034139 regulation of toll-like receptor 3 signaling pathway 1.397144e-4
GO:0010713 negative regulation of collagen metabolic process 1.398987e-4
GO:0002253 activation of immune response 1.409825e-4
GO:0046546 development of primary male sexual characteristics 1.435250e-4
GO:0002251 organ or tissue specific immune response 1.458566e-4
GO:0042036 negative regulation of cytokine biosynthetic process 1.468431e-4
GO:0006417 regulation of translation 1.477614e-4
GO:0034205 beta-amyloid formation 1.494190e-4
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 1.496990e-4
GO:0052572 response to host immune response 1.531295e-4
GO:0051349 positive regulation of lyase activity 1.535834e-4
GO:0007113 endomitotic cell cycle 1.540400e-4
GO:0048148 behavioral response to cocaine 1.561549e-4
GO:0045597 positive regulation of cell differentiation 1.577526e-4
GO:0071503 response to heparin 1.607982e-4
GO:0050890 cognition 1.654035e-4
GO:0010556 regulation of macromolecule biosynthetic process 1.692195e-4
GO:0051222 positive regulation of protein transport 1.705781e-4
GO:0010033 response to organic substance 1.709347e-4
GO:0060341 regulation of cellular localization 1.720856e-4
GO:0051607 defense response to virus 1.738152e-4
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 1.753699e-4
GO:0042221 response to chemical stimulus 1.847821e-4
GO:0050867 positive regulation of cell activation 1.861585e-4
GO:0034103 regulation of tissue remodeling 1.868585e-4
GO:0009886 post-embryonic morphogenesis 1.909981e-4
GO:0009891 positive regulation of biosynthetic process 1.914774e-4
GO:0050778 positive regulation of immune response 1.915449e-4
GO:0072678 T cell migration 1.919546e-4
GO:0070536 protein K63-linked deubiquitination 1.978790e-4
GO:0044260 cellular macromolecule metabolic process 1.991204e-4
GO:0009056 catabolic process 2.010538e-4
GO:0052547 regulation of peptidase activity 2.019566e-4
GO:0032308 positive regulation of prostaglandin secretion 2.030931e-4
GO:0070925 organelle assembly 2.034744e-4
GO:0002696 positive regulation of leukocyte activation 2.079871e-4
GO:0032026 response to magnesium ion 2.081388e-4
GO:0003127 detection of nodal flow 2.086525e-4
GO:0045721 negative regulation of gluconeogenesis 2.170738e-4
GO:0019228 regulation of action potential in neuron 2.174264e-4
GO:0032735 positive regulation of interleukin-12 production 2.190420e-4
GO:0042698 ovulation cycle 2.219831e-4
GO:0002682 regulation of immune system process 2.247764e-4
GO:0008584 male gonad development 2.274306e-4
GO:0002221 pattern recognition receptor signaling pathway 2.313303e-4
GO:0008283 cell proliferation 2.316941e-4
GO:0051171 regulation of nitrogen compound metabolic process 2.326641e-4
GO:0042908 xenobiotic transport 2.349474e-4
GO:0043331 response to dsRNA 2.369412e-4
GO:0010823 negative regulation of mitochondrion organization 2.369779e-4
GO:0022613 ribonucleoprotein complex biogenesis 2.400917e-4
GO:0002446 neutrophil mediated immunity 2.441195e-4
GO:0002832 negative regulation of response to biotic stimulus 2.481752e-4
GO:0010763 positive regulation of fibroblast migration 2.581317e-4
GO:0045089 positive regulation of innate immune response 2.603159e-4
GO:0051716 cellular response to stimulus 2.632949e-4
GO:0035249 synaptic transmission, glutamatergic 2.659506e-4
GO:0042981 regulation of apoptosis 2.676790e-4
GO:0006499 N-terminal protein myristoylation 2.688318e-4
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 2.707864e-4
GO:0051252 regulation of RNA metabolic process 2.733369e-4
GO:0045884 regulation of survival gene product expression 2.766650e-4
GO:0002237 response to molecule of bacterial origin 2.801864e-4
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development 2.803396e-4
GO:0043277 apoptotic cell clearance 2.823653e-4
GO:0019087 transformation of host cell by virus 2.824894e-4
GO:0010614 negative regulation of cardiac muscle hypertrophy 2.842747e-4
GO:0046685 response to arsenic-containing substance 2.868164e-4
GO:0051960 regulation of nervous system development 2.898481e-4
GO:0043067 regulation of programmed cell death 2.912568e-4
GO:0043537 negative regulation of blood vessel endothelial cell migration 2.921013e-4
GO:0002521 leukocyte differentiation 2.934476e-4
GO:0071872 cellular response to epinephrine stimulus 3.006259e-4
GO:0051918 negative regulation of fibrinolysis 3.065295e-4
GO:0071243 cellular response to arsenic-containing substance 3.086724e-4
GO:0008050 female courtship behavior 3.180665e-4
GO:0032496 response to lipopolysaccharide 3.187570e-4
GO:0009249 protein lipoylation 3.252488e-4
GO:0002700 regulation of production of molecular mediator of immune response 3.293113e-4
GO:0030259 lipid glycosylation 3.302799e-4
GO:0006554 lysine catabolic process 3.417411e-4
GO:0008049 male courtship behavior 3.428301e-4
GO:0071404 cellular response to low-density lipoprotein particle stimulus 3.430757e-4
GO:0000085 G2 phase of mitotic cell cycle 3.445066e-4
GO:0016075 rRNA catabolic process 3.537497e-4
GO:0051592 response to calcium ion 3.540031e-4
GO:0016567 protein ubiquitination 3.599201e-4
GO:0050707 regulation of cytokine secretion 3.662948e-4
GO:0006235 dTTP biosynthetic process 3.670757e-4
GO:0034122 negative regulation of toll-like receptor signaling pathway 3.674093e-4
GO:0050482 arachidonic acid secretion 3.705011e-4
GO:0031328 positive regulation of cellular biosynthetic process 3.773282e-4
GO:0016579 protein deubiquitination 3.774192e-4
GO:0034346 positive regulation of type III interferon production 3.807405e-4
GO:0042440 pigment metabolic process 3.821126e-4
GO:0072592 oxygen metabolic process 3.894106e-4
GO:0022414 reproductive process 3.901309e-4
GO:0030098 lymphocyte differentiation 3.988261e-4
GO:0032663 regulation of interleukin-2 production 4.146586e-4
GO:0051707 response to other organism 4.163536e-4
GO:0021547 midbrain-hindbrain boundary initiation 4.170488e-4
GO:0021501 prechordal plate formation 4.170488e-4
GO:0000003 reproduction 4.188191e-4
GO:0045059 positive thymic T cell selection 4.312559e-4
GO:0051282 regulation of sequestering of calcium ion 4.320461e-4
GO:0050921 positive regulation of chemotaxis 4.333453e-4
GO:2000145 regulation of cell motility 4.390239e-4
GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process 4.454329e-4
GO:0034698 response to gonadotropin stimulus 4.645672e-4
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 4.665817e-4
GO:0071333 cellular response to glucose stimulus 4.679792e-4
GO:0051353 positive regulation of oxidoreductase activity 4.680113e-4
GO:0048807 female genitalia morphogenesis 4.706767e-4
GO:0007611 learning or memory 4.740474e-4
GO:0021918 regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment 4.769147e-4
GO:0021905 forebrain-midbrain boundary formation 4.769147e-4
GO:0003322 pancreatic A cell development 4.769147e-4
GO:0021902 commitment of neuronal cell to specific neuron type in forebrain 4.769147e-4
GO:0051209 release of sequestered calcium ion into cytosol 4.778102e-4
GO:0002637 regulation of immunoglobulin production 4.800794e-4
GO:0008152 metabolic process 4.811522e-4
GO:0007243 intracellular protein kinase cascade 4.859349e-4
GO:0034135 regulation of toll-like receptor 2 signaling pathway 5.005622e-4
GO:0060044 negative regulation of cardiac muscle cell proliferation 5.012345e-4
GO:0040014 regulation of multicellular organism growth 5.051127e-4
GO:0035239 tube morphogenesis 5.115214e-4
GO:0071636 positive regulation of transforming growth factor beta production 5.215707e-4
GO:0090201 negative regulation of release of cytochrome c from mitochondria 5.351920e-4
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 5.353007e-4
GO:0022618 ribonucleoprotein complex assembly 5.363296e-4
GO:0048583 regulation of response to stimulus 5.413202e-4
GO:0034633 retinol transport 5.422405e-4
GO:0001834 trophectodermal cell proliferation 5.422405e-4
GO:0002758 innate immune response-activating signal transduction 5.437261e-4
GO:0045732 positive regulation of protein catabolic process 5.458545e-4
GO:0009068 aspartate family amino acid catabolic process 5.476375e-4
GO:0032474 otolith morphogenesis 5.679927e-4
GO:0010611 regulation of cardiac muscle hypertrophy 5.699760e-4
GO:0045085 negative regulation of interleukin-2 biosynthetic process 5.706583e-4
GO:0030970 retrograde protein transport, ER to cytosol 5.706583e-4
GO:0043368 positive T cell selection 5.731699e-4
GO:0032410 negative regulation of transporter activity 5.871727e-4
GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep 5.921426e-4
GO:0006355 regulation of transcription, DNA-dependent 6.055003e-4
GO:0014741 negative regulation of muscle hypertrophy 6.100093e-4
GO:0030278 regulation of ossification 6.141184e-4
GO:0051047 positive regulation of secretion 6.159860e-4
GO:0043217 myelin maintenance 6.163009e-4
GO:0046661 male sex differentiation 6.288217e-4
GO:0033555 multicellular organismal response to stress 6.312996e-4
GO:0046888 negative regulation of hormone secretion 6.435794e-4
GO:0019219 regulation of nucleobase-containing compound metabolic process 6.457686e-4
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 6.688733e-4
GO:0007165 signal transduction 6.766075e-4
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 6.818313e-4
GO:0031644 regulation of neurological system process 6.829033e-4
GO:0071402 cellular response to lipoprotein particle stimulus 6.843857e-4
GO:2000116 regulation of cysteine-type endopeptidase activity 6.868261e-4
GO:0002683 negative regulation of immune system process 6.879399e-4
GO:0043279 response to alkaloid 6.912373e-4
GO:0045087 innate immune response 6.916986e-4
GO:0002286 T cell activation involved in immune response 6.998522e-4
GO:0016265 death 7.093512e-4
GO:0051917 regulation of fibrinolysis 7.224898e-4
GO:0035413 positive regulation of catenin import into nucleus 7.227841e-4
GO:0009200 deoxyribonucleoside triphosphate metabolic process 7.434195e-4
GO:0051969 regulation of transmission of nerve impulse 7.638343e-4
GO:0007059 chromosome segregation 7.642944e-4
GO:0002544 chronic inflammatory response 7.648266e-4
GO:0010596 negative regulation of endothelial cell migration 7.681582e-4
GO:0002604 regulation of dendritic cell antigen processing and presentation 7.686977e-4
GO:0051310 metaphase plate congression 7.767829e-4
GO:0048513 organ development 7.826201e-4
GO:0040012 regulation of locomotion 7.883591e-4
GO:0040040 thermosensory behavior 8.034444e-4
GO:0034112 positive regulation of homotypic cell-cell adhesion 8.034444e-4
GO:0014743 regulation of muscle hypertrophy 8.055308e-4
GO:0042391 regulation of membrane potential 8.095744e-4
GO:0030217 T cell differentiation 8.123022e-4
GO:0048265 response to pain 8.130383e-4
GO:0044403 symbiosis, encompassing mutualism through parasitism 8.207795e-4
GO:0071715 icosanoid transport 8.255512e-4
GO:0009967 positive regulation of signal transduction 8.467899e-4
GO:0007589 body fluid secretion 8.473492e-4
GO:0010467 gene expression 8.780333e-4
GO:0019242 methylglyoxal biosynthetic process 8.812610e-4
GO:0030162 regulation of proteolysis 8.816094e-4
GO:0060152 microtubule-based peroxisome localization 8.898041e-4
GO:0048608 reproductive structure development 8.952982e-4
GO:0060043 regulation of cardiac muscle cell proliferation 9.011854e-4
GO:0060157 urinary bladder development 9.060154e-4
GO:0019836 hemolysis by symbiont of host erythrocytes 9.152004e-4
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 9.235524e-4
GO:0042100 B cell proliferation 9.416537e-4
GO:0071216 cellular response to biotic stimulus 9.422258e-4
GO:0032446 protein modification by small protein conjugation 9.475053e-4
GO:0071460 cellular response to cell-matrix adhesion 9.600738e-4
GO:0048243 norepinephrine secretion 9.643104e-4
GO:0003140 determination of left/right asymmetry in lateral mesoderm 9.711231e-4
GO:0007548 sex differentiation 9.776196e-4
GO:0008219 cell death 9.806289e-4
GO:0071826 ribonucleoprotein complex subunit organization 9.841109e-4
GO:0050830 defense response to Gram-positive bacterium 9.849733e-4
GO:0051895 negative regulation of focal adhesion assembly 9.862955e-4
GO:0050920 regulation of chemotaxis 9.866788e-4
GO:0051051 negative regulation of transport 1.006715e-3
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 1.018065e-3
GO:0030258 lipid modification 1.021339e-3
GO:0006950 response to stress 1.029465e-3
GO:0019098 reproductive behavior 1.036285e-3
GO:0046148 pigment biosynthetic process 1.049561e-3
GO:0050790 regulation of catalytic activity 1.075614e-3
GO:0042489 negative regulation of odontogenesis of dentine-containing tooth 1.078047e-3
GO:0031342 negative regulation of cell killing 1.083299e-3
GO:0034645 cellular macromolecule biosynthetic process 1.084755e-3
GO:0035092 sperm chromatin condensation 1.086763e-3
GO:0016477 cell migration 1.099976e-3
GO:0046677 response to antibiotic 1.102734e-3
GO:0046208 spermine catabolic process 1.103913e-3


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0048240 sperm capacitation 5.015268e-25
GO:0006400 tRNA modification 3.835618e-20
GO:0030488 tRNA methylation 9.494742e-20
GO:0001510 RNA methylation 1.359064e-13
GO:0008033 tRNA processing 2.411205e-13
GO:0009451 RNA modification 4.534992e-12
GO:0048515 spermatid differentiation 7.289033e-12
GO:0007286 spermatid development 3.544791e-10
GO:0055119 relaxation of cardiac muscle 7.934263e-9
GO:0034470 ncRNA processing 1.332099e-8
GO:0046709 IDP catabolic process 1.418331e-8
GO:0046032 ADP catabolic process 1.418331e-8
GO:0034392 negative regulation of smooth muscle cell apoptosis 2.144375e-8
GO:0006581 acetylcholine catabolic process 2.246230e-8
GO:0014904 myotube cell development 5.294943e-8
GO:0006399 tRNA metabolic process 5.557829e-8
GO:0007271 synaptic transmission, cholinergic 8.685295e-8
GO:0060282 positive regulation of oocyte development 8.795969e-8
GO:0060281 regulation of oocyte development 8.795969e-8
GO:0050819 negative regulation of coagulation 9.036183e-8
GO:0009566 fertilization 1.057591e-7
GO:0055118 negative regulation of cardiac muscle contraction 1.595589e-7
GO:0043931 ossification involved in bone maturation 1.595589e-7
GO:0008291 acetylcholine metabolic process 1.679309e-7
GO:0048469 cell maturation 1.721911e-7
GO:0006835 dicarboxylic acid transport 1.966137e-7
GO:0048146 positive regulation of fibroblast proliferation 2.404472e-7
GO:0021700 developmental maturation 2.649516e-7
GO:0018105 peptidyl-serine phosphorylation 3.225081e-7
GO:0030195 negative regulation of blood coagulation 3.378707e-7
GO:0070977 bone maturation 4.763933e-7
GO:0002676 regulation of chronic inflammatory response 4.946818e-7
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 7.827508e-7
GO:0002678 positive regulation of chronic inflammatory response 8.450942e-7
GO:0060741 prostate gland stromal morphogenesis 8.716785e-7
GO:0045212 neurotransmitter receptor biosynthetic process 1.171275e-6
GO:0035630 bone mineralization involved in bone maturation 1.171275e-6
GO:0032878 regulation of establishment or maintenance of cell polarity 1.386940e-6
GO:0043129 surfactant homeostasis 1.489489e-6
GO:0048610 cellular process involved in reproduction 2.301386e-6
GO:0090201 negative regulation of release of cytochrome c from mitochondria 2.361219e-6
GO:0070375 BMK cascade 3.682042e-6
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 3.856833e-6
GO:0010823 negative regulation of mitochondrion organization 3.913853e-6
GO:0070723 response to cholesterol 5.148207e-6
GO:0060736 prostate gland growth 6.050519e-6
GO:0006214 thymidine catabolic process 6.068797e-6
GO:0045213 neurotransmitter receptor metabolic process 6.949493e-6
GO:0040014 regulation of multicellular organism growth 7.463128e-6
GO:0048661 positive regulation of smooth muscle cell proliferation 7.640850e-6
GO:0042772 DNA damage response, signal transduction resulting in transcription 8.337190e-6
GO:0046326 positive regulation of glucose import 8.506410e-6
GO:0051932 synaptic transmission, GABAergic 8.695283e-6
GO:0051224 negative regulation of protein transport 8.949058e-6
GO:0015939 pantothenate metabolic process 9.036237e-6
GO:0010656 negative regulation of muscle cell apoptosis 9.546081e-6
GO:0031558 induction of apoptosis in response to chemical stimulus 1.016802e-5
GO:0010564 regulation of cell cycle process 1.017716e-5
GO:0000492 box C/D snoRNP assembly 1.028007e-5
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 1.060519e-5
GO:0051726 regulation of cell cycle 1.070949e-5
GO:0060740 prostate gland epithelium morphogenesis 1.081161e-5
GO:0003207 cardiac chamber formation 1.198370e-5
GO:0060512 prostate gland morphogenesis 1.284451e-5
GO:0043069 negative regulation of programmed cell death 1.288573e-5
GO:0001974 blood vessel remodeling 1.309993e-5
GO:0048145 regulation of fibroblast proliferation 1.345703e-5
GO:0003211 cardiac ventricle formation 1.618812e-5
GO:0006212 uracil catabolic process 1.665248e-5
GO:0060548 negative regulation of cell death 1.762693e-5
GO:0051534 negative regulation of NFAT protein import into nucleus 1.981925e-5
GO:0046826 negative regulation of protein export from nucleus 2.047517e-5
GO:0031119 tRNA pseudouridine synthesis 2.300973e-5
GO:0046069 cGMP catabolic process 2.387855e-5
GO:0010613 positive regulation of cardiac muscle hypertrophy 2.626753e-5
GO:0009181 purine ribonucleoside diphosphate catabolic process 2.630976e-5
GO:0031397 negative regulation of protein ubiquitination 2.731225e-5
GO:0046373 L-arabinose metabolic process 3.152888e-5
GO:0042311 vasodilation 3.374824e-5
GO:0035234 germ cell programmed cell death 3.387891e-5
GO:0001780 neutrophil homeostasis 3.404221e-5
GO:0006071 glycerol metabolic process 3.432385e-5
GO:0034660 ncRNA metabolic process 3.517815e-5
GO:0007281 germ cell development 3.519054e-5
GO:0007214 gamma-aminobutyric acid signaling pathway 3.661776e-5
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 3.871119e-5
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 3.911787e-5
GO:0046031 ADP metabolic process 4.044479e-5
GO:0009446 putrescine biosynthetic process 4.158841e-5
GO:0006493 protein O-linked glycosylation 4.291235e-5
GO:0043066 negative regulation of apoptosis 4.476635e-5
GO:0060509 Type I pneumocyte differentiation 4.508324e-5
GO:0051450 myoblast proliferation 4.513886e-5
GO:0010828 positive regulation of glucose transport 4.612396e-5
GO:0032101 regulation of response to external stimulus 4.950792e-5
GO:0014743 regulation of muscle hypertrophy 5.135586e-5
GO:0045226 extracellular polysaccharide biosynthetic process 5.262775e-5
GO:0006507 GPI anchor release 5.262775e-5
GO:0031348 negative regulation of defense response 5.464484e-5
GO:0002320 lymphoid progenitor cell differentiation 5.611983e-5
GO:0003215 cardiac right ventricle morphogenesis 6.409915e-5
GO:0048386 positive regulation of retinoic acid receptor signaling pathway 6.584702e-5
GO:0002328 pro-B cell differentiation 6.677716e-5
GO:0031570 DNA integrity checkpoint 6.762963e-5
GO:0000077 DNA damage checkpoint 6.785044e-5
GO:2000241 regulation of reproductive process 6.818051e-5
GO:0060749 mammary gland alveolus development 7.113167e-5
GO:0006222 UMP biosynthetic process 7.285500e-5
GO:0060766 negative regulation of androgen receptor signaling pathway 8.287447e-5
GO:0010941 regulation of cell death 8.297844e-5
GO:0008216 spermidine metabolic process 8.366705e-5
GO:0034391 regulation of smooth muscle cell apoptosis 8.978102e-5
GO:0045786 negative regulation of cell cycle 9.117304e-5
GO:0060525 prostate glandular acinus development 9.686412e-5
GO:0014066 regulation of phosphatidylinositol 3-kinase cascade 1.030814e-4
GO:0071156 regulation of cell cycle arrest 1.079558e-4
GO:0060442 branching involved in prostate gland morphogenesis 1.085067e-4
GO:0061307 cardiac neural crest cell differentiation involved in heart development 1.096591e-4
GO:0009191 ribonucleoside diphosphate catabolic process 1.113698e-4
GO:0006210 thymine catabolic process 1.147860e-4
GO:0019400 alditol metabolic process 1.210307e-4
GO:0014911 positive regulation of smooth muscle cell migration 1.220721e-4
GO:0019695 choline metabolic process 1.235576e-4
GO:0018209 peptidyl-serine modification 1.238814e-4
GO:0015826 threonine transport 1.276992e-4
GO:0034589 hydroxyproline transport 1.276992e-4
GO:0043067 regulation of programmed cell death 1.287093e-4
GO:0001662 behavioral fear response 1.298396e-4
GO:0043501 skeletal muscle adaptation 1.307397e-4
GO:0043620 regulation of DNA-dependent transcription in response to stress 1.309540e-4
GO:0061138 morphogenesis of a branching epithelium 1.358657e-4
GO:0042596 fear response 1.398032e-4
GO:0046823 negative regulation of nucleocytoplasmic transport 1.411701e-4
GO:0048844 artery morphogenesis 1.433824e-4
GO:0002209 behavioral defense response 1.469448e-4
GO:0090317 negative regulation of intracellular protein transport 1.538266e-4
GO:0042135 neurotransmitter catabolic process 1.560288e-4
GO:0046425 regulation of JAK-STAT cascade 1.727987e-4
GO:0043503 skeletal muscle fiber adaptation 1.798563e-4
GO:0032060 bleb assembly 1.798563e-4
GO:0045839 negative regulation of mitosis 1.847232e-4
GO:0010660 regulation of muscle cell apoptosis 1.865648e-4
GO:0035909 aorta morphogenesis 1.865648e-4
GO:0032514 positive regulation of protein phosphatase type 2B activity 1.882702e-4
GO:0009134 nucleoside diphosphate catabolic process 1.893534e-4
GO:0001763 morphogenesis of a branching structure 1.935156e-4
GO:0010611 regulation of cardiac muscle hypertrophy 2.070138e-4
GO:0030850 prostate gland development 2.111494e-4
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 2.116269e-4
GO:0097116 gephyrin clustering 2.153892e-4
GO:0009452 RNA capping 2.161873e-4
GO:0071425 hemopoietic stem cell proliferation 2.186060e-4
GO:0030879 mammary gland development 2.354811e-4
GO:0003006 developmental process involved in reproduction 2.382099e-4
GO:0015711 organic anion transport 2.385660e-4
GO:0071397 cellular response to cholesterol 2.387884e-4
GO:0007614 short-term memory 2.435005e-4
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 2.463627e-4
GO:0035910 ascending aorta morphogenesis 2.463627e-4
GO:0002244 hemopoietic progenitor cell differentiation 2.499840e-4
GO:0010948 negative regulation of cell cycle process 2.684096e-4
GO:0046587 positive regulation of calcium-dependent cell-cell adhesion 2.707409e-4
GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport 2.707409e-4
GO:0048814 regulation of dendrite morphogenesis 2.720171e-4
GO:0006974 response to DNA damage stimulus 2.793758e-4
GO:0022616 DNA strand elongation 2.801711e-4
GO:0045821 positive regulation of glycolysis 2.810642e-4
GO:0032102 negative regulation of response to external stimulus 2.868137e-4
GO:0042981 regulation of apoptosis 2.882511e-4
GO:0007263 nitric oxide mediated signal transduction 2.932641e-4
GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage 3.074930e-4
GO:0032801 receptor catabolic process 3.198507e-4
GO:0060134 prepulse inhibition 3.269250e-4
GO:0010544 negative regulation of platelet activation 3.643407e-4
GO:0000075 cell cycle checkpoint 3.684149e-4
GO:0060563 neuroepithelial cell differentiation 4.055658e-4
GO:0032868 response to insulin stimulus 4.490695e-4
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 4.545088e-4
GO:0042402 cellular biogenic amine catabolic process 4.556831e-4
GO:0008016 regulation of heart contraction 4.587850e-4
GO:0019089 transmission of virus 4.703335e-4
GO:0044111 development involved in symbiotic interaction 4.703335e-4
GO:0015825 L-serine transport 4.703335e-4
GO:0010768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage 4.703335e-4
GO:0070201 regulation of establishment of protein localization 4.783636e-4
GO:0014888 striated muscle adaptation 4.906946e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 4.941171e-4
GO:0042350 GDP-L-fucose biosynthetic process 5.120793e-4
GO:0015811 L-cystine transport 5.120793e-4
GO:0033136 serine phosphorylation of STAT3 protein 5.120793e-4
GO:0003183 mitral valve morphogenesis 5.141585e-4
GO:0014896 muscle hypertrophy 5.371854e-4
GO:0003230 cardiac atrium development 5.384664e-4
GO:0048754 branching morphogenesis of a tube 5.390660e-4
GO:0042501 serine phosphorylation of STAT protein 5.794117e-4
GO:0090273 regulation of somatostatin secretion 5.893023e-4
GO:0046121 deoxyribonucleoside catabolic process 5.978456e-4
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.978456e-4
GO:2000425 regulation of apoptotic cell clearance 6.092247e-4
GO:0021801 cerebral cortex radial glia guided migration 6.133119e-4
GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 6.133119e-4
GO:0010466 negative regulation of peptidase activity 6.360580e-4
GO:0031400 negative regulation of protein modification process 6.624833e-4
GO:0006396 RNA processing 6.742890e-4
GO:0034224 cellular response to zinc ion starvation 6.840644e-4
GO:0019532 oxalate transport 6.840644e-4
GO:0002683 negative regulation of immune system process 7.161319e-4
GO:0050765 negative regulation of phagocytosis 7.410380e-4
GO:0032800 receptor biosynthetic process 7.583482e-4
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 7.659662e-4
GO:2000243 positive regulation of reproductive process 7.704787e-4
GO:0090075 relaxation of muscle 7.763532e-4
GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis 7.863604e-4
GO:0051223 regulation of protein transport 7.934531e-4
GO:2000826 regulation of heart morphogenesis 8.033711e-4
GO:0000380 alternative nuclear mRNA splicing, via spliceosome 8.080868e-4
GO:0031342 negative regulation of cell killing 8.157594e-4
GO:0006370 mRNA capping 8.499707e-4
GO:0048478 replication fork protection 8.782590e-4
GO:0014057 positive regulation of acetylcholine secretion 8.782590e-4
GO:0060840 artery development 8.806480e-4
GO:0031442 positive regulation of mRNA 3'-end processing 8.860523e-4
GO:0003283 atrial septum development 8.965932e-4
GO:0003357 noradrenergic neuron differentiation 9.130938e-4
GO:0050818 regulation of coagulation 9.802669e-4
GO:0035588 G-protein coupled purinergic receptor signaling pathway 9.841971e-4
GO:0001541 ovarian follicle development 9.854379e-4
GO:0006916 anti-apoptosis 9.995532e-4
GO:0022612 gland morphogenesis 9.996357e-4
GO:0071695 anatomical structure maturation 1.008757e-3
GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1.029568e-3
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 1.032096e-3
GO:0097118 neuroligin clustering 1.044227e-3
GO:0009896 positive regulation of catabolic process 1.050849e-3
GO:0019227 neuronal action potential propagation 1.051675e-3
GO:0035108 limb morphogenesis 1.078527e-3
GO:0048485 sympathetic nervous system development 1.092018e-3
GO:0050679 positive regulation of epithelial cell proliferation 1.117697e-3
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.144131e-3
GO:0001887 selenium compound metabolic process 1.150701e-3
GO:0043526 neuroprotection 1.155124e-3
GO:0061325 cell proliferation involved in outflow tract morphogenesis 1.161420e-3
GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis 1.161420e-3
GO:0048304 positive regulation of isotype switching to IgG isotypes 1.176489e-3
GO:0072395 signal transduction involved in cell cycle checkpoint 1.218092e-3
GO:0022610 biological adhesion 1.227645e-3
GO:0060730 regulation of intestinal epithelial structure maintenance 1.243613e-3
GO:0042351 'de novo' GDP-L-fucose biosynthetic process 1.243613e-3
GO:0035883 enteroendocrine cell differentiation 1.243613e-3
GO:0043403 skeletal muscle tissue regeneration 1.269457e-3
GO:0072329 monocarboxylic acid catabolic process 1.276911e-3
GO:0002698 negative regulation of immune effector process 1.282729e-3
GO:0007155 cell adhesion 1.296161e-3
GO:0007399 nervous system development 1.327044e-3
GO:0050728 negative regulation of inflammatory response 1.337994e-3
GO:0000723 telomere maintenance 1.349661e-3
GO:2000602 regulation of interphase of mitotic cell cycle 1.354669e-3
GO:0060039 pericardium development 1.355961e-3
GO:0000082 G1/S transition of mitotic cell cycle 1.359061e-3
GO:0051054 positive regulation of DNA metabolic process 1.367674e-3
GO:0051262 protein tetramerization 1.380735e-3
GO:0042770 signal transduction in response to DNA damage 1.386413e-3
GO:0008295 spermidine biosynthetic process 1.400810e-3
GO:0003209 cardiac atrium morphogenesis 1.420220e-3
GO:0030193 regulation of blood coagulation 1.425492e-3
GO:0007405 neuroblast proliferation 1.425892e-3
GO:0031018 endocrine pancreas development 1.451320e-3
GO:0031860 telomeric 3' overhang formation 1.474027e-3
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.474027e-3
GO:0001971 negative regulation of activation of membrane attack complex 1.474027e-3
GO:0006432 phenylalanyl-tRNA aminoacylation 1.474548e-3
GO:0046777 protein autophosphorylation 1.480443e-3
GO:0072422 signal transduction involved in DNA damage checkpoint 1.480538e-3
GO:0015908 fatty acid transport 1.561814e-3
GO:0061041 regulation of wound healing 1.600174e-3
GO:0035904 aorta development 1.618467e-3
GO:0046579 positive regulation of Ras protein signal transduction 1.618467e-3
GO:0043112 receptor metabolic process 1.658755e-3
GO:0018343 protein farnesylation 1.683339e-3
GO:0043500 muscle adaptation 1.684406e-3
GO:0010867 positive regulation of triglyceride biosynthetic process 1.691097e-3
GO:0032329 serine transport 1.699752e-3
GO:0019673 GDP-mannose metabolic process 1.699752e-3
GO:0015808 L-alanine transport 1.699752e-3
GO:0051532 regulation of NFAT protein import into nucleus 1.715447e-3
GO:0009185 ribonucleoside diphosphate metabolic process 1.723145e-3
GO:0071773 cellular response to BMP stimulus 1.796653e-3
GO:0002076 osteoblast development 1.801093e-3
GO:0019233 sensory perception of pain 1.819103e-3
GO:0019395 fatty acid oxidation 1.825993e-3
GO:0035584 calcium-mediated signaling using intracellular calcium source 1.851719e-3
GO:0051899 membrane depolarization 1.871501e-3
GO:0072404 signal transduction involved in G1/S transition checkpoint 1.885026e-3
GO:0006622 protein targeting to lysosome 1.891286e-3
GO:0007090 regulation of S phase of mitotic cell cycle 2.019357e-3
GO:0015718 monocarboxylic acid transport 2.031916e-3
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 2.041119e-3
GO:0021861 forebrain radial glial cell differentiation 2.041353e-3
GO:0021795 cerebral cortex cell migration 2.049500e-3
GO:0060041 retina development in camera-type eye 2.078200e-3
GO:0046427 positive regulation of JAK-STAT cascade 2.081977e-3
GO:0080134 regulation of response to stress 2.104092e-3
GO:0045740 positive regulation of DNA replication 2.122424e-3
GO:0042119 neutrophil activation 2.127339e-3
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 2.189071e-3
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 2.217902e-3
GO:2000352 negative regulation of endothelial cell apoptosis 2.219543e-3
GO:0042769 DNA damage response, detection of DNA damage 2.219543e-3
GO:0035881 amacrine cell differentiation 2.227153e-3
GO:0031508 centromeric heterochromatin formation 2.227153e-3
GO:0043558 regulation of translational initiation in response to stress 2.297595e-3
GO:0072513 positive regulation of secondary heart field cardioblast proliferation 2.306122e-3
GO:0060011 Sertoli cell proliferation 2.306122e-3
GO:0006596 polyamine biosynthetic process 2.306122e-3
GO:0061308 cardiac neural crest cell development involved in heart development 2.352145e-3
GO:0060737 prostate gland morphogenetic growth 2.352145e-3
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2.356660e-3
GO:0006004 fucose metabolic process 2.357862e-3
GO:0061029 eyelid development in camera-type eye 2.403732e-3
GO:0006090 pyruvate metabolic process 2.406927e-3
GO:0060536 cartilage morphogenesis 2.422893e-3
GO:0032094 response to food 2.508415e-3
GO:0032880 regulation of protein localization 2.537728e-3
GO:0031440 regulation of mRNA 3'-end processing 2.595937e-3
GO:0001915 negative regulation of T cell mediated cytotoxicity 2.609090e-3
GO:0045683 negative regulation of epidermis development 2.632216e-3
GO:0050880 regulation of blood vessel size 2.654291e-3
GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process 2.673019e-3
GO:0032200 telomere organization 2.695242e-3
GO:0008585 female gonad development 2.695459e-3
GO:0051346 negative regulation of hydrolase activity 2.733061e-3
GO:0035150 regulation of tube size 2.737857e-3
GO:0010766 negative regulation of sodium ion transport 2.742184e-3
GO:0009062 fatty acid catabolic process 2.757448e-3
GO:0060174 limb bud formation 2.804671e-3
GO:0051451 myoblast migration 2.819669e-3
GO:0031347 regulation of defense response 2.820562e-3
GO:0032147 activation of protein kinase activity 2.826615e-3
GO:0002053 positive regulation of mesenchymal cell proliferation 2.828649e-3
GO:0071403 cellular response to high density lipoprotein particle stimulus 2.828696e-3
GO:0071448 cellular response to alkyl hydroperoxide 2.828696e-3
GO:0071315 cellular response to morphine 2.828696e-3
GO:0031269 pseudopodium assembly 2.828696e-3
GO:0071307 cellular response to vitamin K 2.828696e-3
GO:0010430 fatty acid omega-oxidation 2.828696e-3
GO:0050904 diapedesis 2.828696e-3
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 2.871137e-3
GO:0060973 cell migration involved in heart development 2.913435e-3
GO:0060413 atrial septum morphogenesis 2.924880e-3
GO:0090187 positive regulation of pancreatic juice secretion 2.949662e-3
GO:0090340 positive regulation of secretion of lysosomal enzymes 2.949662e-3
GO:0090108 positive regulation of high-density lipoprotein particle assembly 2.949662e-3
GO:0070827 chromatin maintenance 2.949662e-3
GO:0035945 mitochondrial ncRNA surveillance 2.949662e-3
GO:0035946 mitochondrial mRNA surveillance 2.949662e-3
GO:0031118 rRNA pseudouridine synthesis 2.949662e-3
GO:0031623 receptor internalization 2.951414e-3
GO:0002009 morphogenesis of an epithelium 2.959163e-3
GO:0001766 membrane raft polarization 3.024812e-3
GO:0022602 ovulation cycle process 3.027453e-3
GO:0051893 regulation of focal adhesion assembly 3.057906e-3
GO:0048286 lung alveolus development 3.083891e-3
GO:0060279 positive regulation of ovulation 3.083924e-3
GO:0060414 aorta smooth muscle tissue morphogenesis 3.210993e-3
GO:0031340 positive regulation of vesicle fusion 3.210993e-3
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation 3.228229e-3
GO:0001963 synaptic transmission, dopaminergic 3.273120e-3
GO:0003266 regulation of secondary heart field cardioblast proliferation 3.363477e-3
GO:0050866 negative regulation of cell activation 3.376823e-3
GO:0034720 histone H3-K4 demethylation 3.388394e-3
GO:0033261 regulation of S phase 3.430579e-3
GO:0045059 positive thymic T cell selection 3.465237e-3
GO:0048385 regulation of retinoic acid receptor signaling pathway 3.480294e-3
GO:0042760 very long-chain fatty acid catabolic process 3.542280e-3
GO:0003218 cardiac left ventricle formation 3.542280e-3
GO:0001547 antral ovarian follicle growth 3.584574e-3
GO:0060765 regulation of androgen receptor signaling pathway 3.602357e-3
GO:0003179 heart valve morphogenesis 3.659416e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 3.675591e-3
GO:0030330 DNA damage response, signal transduction by p53 class mediator 3.807249e-3
GO:0051239 regulation of multicellular organismal process 3.810494e-3
GO:0007283 spermatogenesis 3.813638e-3
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 3.932083e-3
GO:0021799 cerebral cortex radially oriented cell migration 3.932083e-3
GO:2000351 regulation of endothelial cell apoptosis 3.943886e-3
GO:0031394 positive regulation of prostaglandin biosynthetic process 3.961586e-3
GO:0006556 S-adenosylmethionine biosynthetic process 3.961586e-3
GO:0032943 mononuclear cell proliferation 4.004728e-3
GO:0046651 lymphocyte proliferation 4.066998e-3
GO:0060019 radial glial cell differentiation 4.122168e-3
GO:0060173 limb development 4.155996e-3
GO:0051665 membrane raft localization 4.182396e-3
GO:0034440 lipid oxidation 4.241487e-3
GO:0048483 autonomic nervous system development 4.268155e-3
GO:0034637 cellular carbohydrate biosynthetic process 4.279197e-3
GO:0051051 negative regulation of transport 4.357500e-3
GO:0008283 cell proliferation 4.399511e-3
GO:0006595 polyamine metabolic process 4.434654e-3
GO:0051930 regulation of sensory perception of pain 4.451365e-3
GO:0060751 branch elongation involved in mammary gland duct branching 4.524807e-3
GO:0003289 atrial septum primum morphogenesis 4.585455e-3
GO:0050727 regulation of inflammatory response 4.589363e-3
GO:0045830 positive regulation of isotype switching 4.606205e-3
GO:0051799 negative regulation of hair follicle development 4.615563e-3
GO:0009258 10-formyltetrahydrofolate catabolic process 4.616878e-3
GO:0003329 pancreatic PP cell fate commitment 4.616878e-3
GO:0003326 pancreatic A cell fate commitment 4.616878e-3
GO:0048745 smooth muscle tissue development 4.708262e-3
GO:0055107 Golgi to secretory granule transport 4.750378e-3
GO:0001811 negative regulation of type I hypersensitivity 4.750378e-3
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process 4.750378e-3
GO:0030328 prenylcysteine catabolic process 4.750378e-3
GO:0002638 negative regulation of immunoglobulin production 4.750378e-3
GO:0030324 lung development 4.752502e-3
GO:0060068 vagina development 4.785289e-3
GO:0006207 'de novo' pyrimidine base biosynthetic process 4.894215e-3
GO:0032494 response to peptidoglycan 4.956852e-3
GO:0060444 branching involved in mammary gland duct morphogenesis 4.974805e-3
GO:0033138 positive regulation of peptidyl-serine phosphorylation 4.991153e-3
GO:0021575 hindbrain morphogenesis 5.072790e-3
GO:0051100 negative regulation of binding 5.093516e-3
GO:0042701 progesterone secretion 5.237789e-3
GO:0035524 proline transmembrane transport 5.237789e-3
GO:0046324 regulation of glucose import 5.335774e-3
GO:0071391 cellular response to estrogen stimulus 5.347009e-3
GO:0043001 Golgi to plasma membrane protein transport 5.384416e-3
GO:0001707 mesoderm formation 5.398549e-3
GO:0006108 malate metabolic process 5.435840e-3
GO:0006275 regulation of DNA replication 5.462586e-3
GO:0060541 respiratory system development 5.480687e-3
GO:0048747 muscle fiber development 5.539435e-3
GO:0003170 heart valve development 5.586286e-3
GO:0090045 positive regulation of deacetylase activity 5.605561e-3
GO:0003151 outflow tract morphogenesis 5.610941e-3
GO:0070661 leukocyte proliferation 5.615409e-3
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 5.640997e-3
GO:0006820 anion transport 5.676639e-3
GO:0007346 regulation of mitotic cell cycle 5.696613e-3
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 5.702219e-3
GO:0019751 polyol metabolic process 5.745922e-3
GO:0032512 regulation of protein phosphatase type 2B activity 5.825243e-3
GO:0021623 oculomotor nerve formation 5.825243e-3
GO:0003409 optic cup structural organization 5.825243e-3
GO:0005989 lactose biosynthetic process 5.825243e-3
GO:0003404 optic vesicle morphogenesis 5.825243e-3
GO:0008285 negative regulation of cell proliferation 5.836228e-3
GO:0003219 cardiac right ventricle formation 5.847278e-3
GO:0032870 cellular response to hormone stimulus 5.961612e-3
GO:0046633 alpha-beta T cell proliferation 5.998468e-3
GO:0060523 prostate epithelial cord elongation 6.096610e-3
GO:0021557 oculomotor nerve development 6.096610e-3
GO:0032025 response to cobalt ion 6.096610e-3
GO:0032328 alanine transport 6.125290e-3
GO:0060426 lung vasculature development 6.133379e-3
GO:0006893 Golgi to plasma membrane transport 6.133379e-3
GO:0090199 regulation of release of cytochrome c from mitochondria 6.192248e-3
GO:0030323 respiratory tube development 6.226896e-3
GO:0040018 positive regulation of multicellular organism growth 6.262182e-3
GO:0045445 myoblast differentiation 6.276071e-3
GO:0043923 positive regulation by host of viral transcription 6.350364e-3
GO:0035019 somatic stem cell maintenance 6.356676e-3
GO:0070372 regulation of ERK1 and ERK2 cascade 6.424815e-3
GO:0009220 pyrimidine ribonucleotide biosynthetic process 6.426257e-3
GO:0002707 negative regulation of lymphocyte mediated immunity 6.532489e-3
GO:0021563 glossopharyngeal nerve development 6.605392e-3
GO:0031952 regulation of protein autophosphorylation 6.732588e-3
GO:0045988 negative regulation of striated muscle contraction 6.769432e-3
GO:0071281 cellular response to iron ion 6.845432e-3
GO:0051057 positive regulation of small GTPase mediated signal transduction 6.877712e-3
GO:0006145 purine base catabolic process 7.012129e-3
GO:0055117 regulation of cardiac muscle contraction 7.013827e-3
GO:0010165 response to X-ray 7.104917e-3
GO:0001654 eye development 7.116469e-3
GO:0043010 camera-type eye development 7.122600e-3
GO:0043922 negative regulation by host of viral transcription 7.258858e-3
GO:0048333 mesodermal cell differentiation 7.275250e-3
GO:0010756 positive regulation of plasminogen activation 7.294669e-3
GO:0042921 glucocorticoid receptor signaling pathway 7.314795e-3
GO:0021940 positive regulation of cerebellar granule cell precursor proliferation 7.314795e-3
GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis 7.318533e-3
GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 7.318533e-3
GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure 7.318533e-3
GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 7.318533e-3
GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 7.318533e-3
GO:2000055 positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 7.318533e-3
GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning 7.318533e-3
GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 7.318533e-3
GO:0031914 negative regulation of synaptic plasticity 7.318533e-3
GO:0061310 canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development 7.318533e-3
GO:0010543 regulation of platelet activation 7.585244e-3
GO:0060706 cell differentiation involved in embryonic placenta development 7.668706e-3
GO:0060463 lung lobe morphogenesis 7.727514e-3
GO:0050678 regulation of epithelial cell proliferation 7.743083e-3
GO:0008284 positive regulation of cell proliferation 7.787478e-3
GO:0045168 cell-cell signaling involved in cell fate commitment 7.836610e-3
GO:0034341 response to interferon-gamma 7.862112e-3
GO:0042698 ovulation cycle 7.874503e-3
GO:0032897 negative regulation of viral transcription 7.961138e-3
GO:0045916 negative regulation of complement activation 7.990620e-3
GO:0003018 vascular process in circulatory system 8.008372e-3