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Novel motif:7

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name:motif7_CGNATC

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0042506 tyrosine phosphorylation of Stat5 protein 1.000792e-9
GO:0045911 positive regulation of DNA recombination 1.359701e-8
GO:0000018 regulation of DNA recombination 3.199208e-8
GO:0000416 positive regulation of histone H3-K36 methylation 1.342466e-7
GO:0045830 positive regulation of isotype switching 2.619284e-7
GO:0006289 nucleotide-excision repair 4.057882e-7
GO:0009145 purine nucleoside triphosphate biosynthetic process 4.785308e-7
GO:0097151 positive regulation of inhibitory postsynaptic membrane potential 4.991831e-7
GO:0045684 positive regulation of epidermis development 7.437033e-7
GO:0009142 nucleoside triphosphate biosynthetic process 8.064215e-7
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 1.414701e-6
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 2.061730e-6
GO:0006164 purine nucleotide biosynthetic process 2.215631e-6
GO:0006344 maintenance of chromatin silencing 2.368030e-6
GO:0046939 nucleotide phosphorylation 2.501689e-6
GO:0006458 'de novo' protein folding 2.578128e-6
GO:0043044 ATP-dependent chromatin remodeling 3.371423e-6
GO:0015862 uridine transport 3.400193e-6
GO:0009201 ribonucleoside triphosphate biosynthetic process 3.665556e-6
GO:0072522 purine-containing compound biosynthetic process 3.737012e-6
GO:0043486 histone exchange 3.915035e-6
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 4.115393e-6
GO:0021592 fourth ventricle development 4.199366e-6
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 4.801687e-6
GO:0045109 intermediate filament organization 4.849918e-6
GO:0021993 initiation of neural tube closure 5.460653e-6
GO:0034470 ncRNA processing 5.986497e-6
GO:0035344 hypoxanthine transport 7.225038e-6
GO:0035364 thymine transport 7.225038e-6
GO:0015854 guanine transport 7.225038e-6
GO:0006283 transcription-coupled nucleotide-excision repair 7.390495e-6
GO:0042866 pyruvate biosynthetic process 7.839401e-6
GO:0009071 serine family amino acid catabolic process 8.828777e-6
GO:0032472 Golgi calcium ion transport 9.665951e-6
GO:0030026 cellular manganese ion homeostasis 9.665951e-6
GO:0032468 Golgi calcium ion homeostasis 9.665951e-6
GO:0006271 DNA strand elongation involved in DNA replication 9.703222e-6
GO:0015853 adenine transport 1.026845e-5
GO:0031444 slow-twitch skeletal muscle fiber contraction 1.084656e-5
GO:0006668 sphinganine-1-phosphate metabolic process 1.244729e-5
GO:0006565 L-serine catabolic process 1.255356e-5
GO:0048298 positive regulation of isotype switching to IgA isotypes 1.259223e-5
GO:0008272 sulfate transport 1.270639e-5
GO:0051084 'de novo' posttranslational protein folding 1.437510e-5
GO:0043353 enucleate erythrocyte differentiation 1.549057e-5
GO:0006754 ATP biosynthetic process 1.625828e-5
GO:0070489 T cell aggregation 1.645371e-5
GO:0035356 cellular triglyceride homeostasis 1.645371e-5
GO:0009152 purine ribonucleotide biosynthetic process 1.769206e-5
GO:0006302 double-strand break repair 1.878459e-5
GO:0072553 terminal button organization 1.926476e-5
GO:0045606 positive regulation of epidermal cell differentiation 1.984795e-5
GO:0009260 ribonucleotide biosynthetic process 1.993447e-5
GO:0006281 DNA repair 2.192122e-5
GO:0010890 positive regulation of sequestering of triglyceride 2.303645e-5
GO:0042147 retrograde transport, endosome to Golgi 2.879901e-5
GO:0048484 enteric nervous system development 2.981575e-5
GO:0014707 branchiomeric skeletal muscle development 3.111025e-5
GO:0000722 telomere maintenance via recombination 3.342147e-5
GO:0032201 telomere maintenance via semi-conservative replication 3.594533e-5
GO:0006670 sphingosine metabolic process 3.599067e-5
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 3.923239e-5
GO:0072126 positive regulation of glomerular mesangial cell proliferation 4.072651e-5
GO:0071506 cellular response to mycophenolic acid 4.072651e-5
GO:0021892 cerebral cortex GABAergic interneuron differentiation 4.121489e-5
GO:0034080 CenH3-containing nucleosome assembly at centromere 4.188399e-5
GO:0060087 relaxation of vascular smooth muscle 4.253963e-5
GO:0042503 tyrosine phosphorylation of Stat3 protein 4.411860e-5
GO:0031468 nuclear envelope reassembly 4.452764e-5
GO:0007184 SMAD protein import into nucleus 4.636196e-5
GO:0007413 axonal fasciculation 4.651913e-5
GO:0016073 snRNA metabolic process 5.252490e-5
GO:0006303 double-strand break repair via nonhomologous end joining 5.373371e-5
GO:0022616 DNA strand elongation 6.106866e-5
GO:0006261 DNA-dependent DNA replication 6.126531e-5
GO:0071044 histone mRNA catabolic process 6.665486e-5
GO:0006270 DNA-dependent DNA replication initiation 6.849921e-5
GO:0007431 salivary gland development 6.890255e-5
GO:0015858 nucleoside transport 7.133747e-5
GO:0019049 evasion of host defenses by virus 7.294145e-5
GO:0090150 establishment of protein localization in membrane 8.051328e-5
GO:0009259 ribonucleotide metabolic process 8.697729e-5
GO:0045110 intermediate filament bundle assembly 9.100657e-5
GO:0000414 regulation of histone H3-K36 methylation 9.100657e-5
GO:0060668 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling 9.238295e-5
GO:0006420 arginyl-tRNA aminoacylation 1.007592e-4
GO:0071028 nuclear mRNA surveillance 1.007592e-4
GO:0015864 pyrimidine nucleoside transport 1.063701e-4
GO:0008033 tRNA processing 1.095204e-4
GO:0070192 chromosome organization involved in meiosis 1.149939e-4
GO:0007127 meiosis I 1.229097e-4
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 1.274980e-4
GO:0034660 ncRNA metabolic process 1.330961e-4
GO:0033299 secretion of lysosomal enzymes 1.370301e-4
GO:0010625 positive regulation of Schwann cell proliferation 1.408688e-4
GO:0032929 negative regulation of superoxide anion generation 1.444339e-4
GO:0009150 purine ribonucleotide metabolic process 1.483179e-4
GO:0010833 telomere maintenance via telomere lengthening 1.557312e-4
GO:0031167 rRNA methylation 1.617944e-4
GO:0090002 establishment of protein localization in plasma membrane 1.642675e-4
GO:0035093 spermatogenesis, exchange of chromosomal proteins 1.685327e-4
GO:0009205 purine ribonucleoside triphosphate metabolic process 1.888102e-4
GO:0010701 positive regulation of norepinephrine secretion 1.929813e-4
GO:0021678 third ventricle development 1.937793e-4
GO:0006260 DNA replication 1.994006e-4
GO:0002438 acute inflammatory response to antigenic stimulus 2.199673e-4
GO:0010189 vitamin E biosynthetic process 2.199673e-4
GO:0009199 ribonucleoside triphosphate metabolic process 2.239711e-4
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 2.307227e-4
GO:0009817 defense response to fungus, incompatible interaction 2.307227e-4
GO:0032287 peripheral nervous system myelin maintenance 2.316059e-4
GO:0007435 salivary gland morphogenesis 2.405745e-4
GO:0002889 regulation of immunoglobulin mediated immune response 2.612373e-4
GO:0051321 meiotic cell cycle 2.655402e-4
GO:0032383 regulation of intracellular cholesterol transport 2.674221e-4
GO:0001798 positive regulation of type IIa hypersensitivity 2.714206e-4
GO:0009144 purine nucleoside triphosphate metabolic process 2.729329e-4
GO:0007183 SMAD protein complex assembly 2.747408e-4
GO:0051588 regulation of neurotransmitter transport 2.784948e-4
GO:0000019 regulation of mitotic recombination 2.871930e-4
GO:0032967 positive regulation of collagen biosynthetic process 2.965310e-4
GO:0010520 regulation of reciprocal meiotic recombination 3.052508e-4
GO:0060445 branching involved in salivary gland morphogenesis 3.070831e-4
GO:0008334 histone mRNA metabolic process 3.074066e-4
GO:0015866 ADP transport 3.132353e-4
GO:0044253 positive regulation of multicellular organismal metabolic process 3.169496e-4
GO:0042254 ribosome biogenesis 3.263668e-4
GO:0006457 protein folding 3.345128e-4
GO:0045039 protein import into mitochondrial inner membrane 3.370703e-4
GO:2000427 positive regulation of apoptotic cell clearance 3.553267e-4
GO:0072111 cell proliferation involved in kidney development 3.578538e-4
GO:0070947 neutrophil mediated killing of fungus 3.587498e-4
GO:0002712 regulation of B cell mediated immunity 3.616495e-4
GO:0006297 nucleotide-excision repair, DNA gap filling 3.620286e-4
GO:0045191 regulation of isotype switching 3.682393e-4
GO:0046732 active induction of host immune response by virus 3.754508e-4
GO:0051580 regulation of neurotransmitter uptake 3.948132e-4
GO:0010936 negative regulation of macrophage cytokine production 3.973358e-4
GO:0000726 non-recombinational repair 4.051582e-4
GO:0034389 lipid particle organization 4.091897e-4
GO:0016191 synaptic vesicle uncoating 4.251889e-4
GO:0033490 cholesterol biosynthetic process via lathosterol 4.251889e-4
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 4.346842e-4
GO:0007339 binding of sperm to zona pellucida 4.408787e-4
GO:0006944 cellular membrane fusion 4.488372e-4
GO:0060707 trophoblast giant cell differentiation 4.512202e-4
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity 4.539484e-4
GO:0016568 chromatin modification 4.572456e-4
GO:0006268 DNA unwinding involved in replication 4.651677e-4
GO:0045835 negative regulation of meiosis 4.774624e-4
GO:0060020 Bergmann glial cell differentiation 4.858251e-4
GO:0033605 positive regulation of catecholamine secretion 4.868746e-4
GO:0051954 positive regulation of amine transport 5.037918e-4
GO:0019883 antigen processing and presentation of endogenous antigen 5.104112e-4
GO:0046604 positive regulation of mitotic centrosome separation 5.268160e-4
GO:0010734 negative regulation of protein glutathionylation 5.291224e-4
GO:0008049 male courtship behavior 5.291224e-4
GO:0048266 behavioral response to pain 5.720902e-4
GO:0035426 extracellular matrix-cell signaling 5.738698e-4
GO:0009106 lipoate metabolic process 5.821348e-4
GO:0045792 negative regulation of cell size 5.940769e-4
GO:0043249 erythrocyte maturation 5.982214e-4
GO:0045217 cell-cell junction maintenance 6.124245e-4
GO:0031055 chromatin remodeling at centromere 6.216786e-4
GO:0007129 synapsis 6.238485e-4
GO:0007126 meiosis 6.284322e-4
GO:0072110 glomerular mesangial cell proliferation 6.636393e-4
GO:0045986 negative regulation of smooth muscle contraction 6.636393e-4
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 6.767968e-4
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 6.767968e-4
GO:0043174 nucleoside salvage 6.930874e-4
GO:0051225 spindle assembly 7.292978e-4
GO:0010430 fatty acid omega-oxidation 7.657010e-4
GO:0007131 reciprocal meiotic recombination 7.967729e-4
GO:0001941 postsynaptic membrane organization 8.035008e-4
GO:0090399 replicative senescence 8.212104e-4
GO:0060706 cell differentiation involved in embryonic placenta development 8.321784e-4
GO:0000154 rRNA modification 9.016350e-4
GO:0071593 lymphocyte aggregation 9.089903e-4
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 1.027503e-3
GO:0031120 snRNA pseudouridine synthesis 1.035401e-3
GO:0001555 oocyte growth 1.035401e-3
GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus 1.035401e-3
GO:0032916 positive regulation of transforming growth factor beta3 production 1.046926e-3
GO:0009141 nucleoside triphosphate metabolic process 1.107092e-3
GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development 1.139567e-3
GO:0050765 negative regulation of phagocytosis 1.142288e-3
GO:0061025 membrane fusion 1.181536e-3
GO:0046730 induction of host immune response by virus 1.200162e-3
GO:0031536 positive regulation of exit from mitosis 1.200162e-3
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 1.211838e-3
GO:0042360 vitamin E metabolic process 1.213842e-3
GO:0045618 positive regulation of keratinocyte differentiation 1.241787e-3
GO:0031284 positive regulation of guanylate cyclase activity 1.258163e-3
GO:0010693 negative regulation of alkaline phosphatase activity 1.258163e-3
GO:0006756 AMP phosphorylation 1.264165e-3
GO:0006430 lysyl-tRNA aminoacylation 1.264165e-3
GO:0032200 telomere organization 1.286008e-3
GO:0072109 glomerular mesangium development 1.289550e-3
GO:0045103 intermediate filament-based process 1.291443e-3
GO:0001830 trophectodermal cell fate commitment 1.296684e-3
GO:0070943 neutrophil mediated killing of symbiont cell 1.369965e-3
GO:0035036 sperm-egg recognition 1.409804e-3
GO:0000733 DNA strand renaturation 1.425972e-3
GO:0045347 negative regulation of MHC class II biosynthetic process 1.427863e-3
GO:0006610 ribosomal protein import into nucleus 1.438139e-3
GO:0051054 positive regulation of DNA metabolic process 1.474226e-3
GO:0090174 organelle membrane fusion 1.491893e-3
GO:0006171 cAMP biosynthetic process 1.497205e-3
GO:0002513 tolerance induction to self antigen 1.525304e-3
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 1.578900e-3
GO:0006379 mRNA cleavage 1.603944e-3
GO:0071956 cellular component maintenance at cellular level 1.623341e-3
GO:0001970 positive regulation of activation of membrane attack complex 1.642289e-3
GO:0033233 regulation of protein sumoylation 1.653014e-3
GO:0035092 sperm chromatin condensation 1.654561e-3
GO:0032235 negative regulation of calcium ion transport via store-operated calcium channel activity 1.674725e-3
GO:0071025 RNA surveillance 1.674725e-3
GO:0016180 snRNA processing 1.703939e-3
GO:0006695 cholesterol biosynthetic process 1.724571e-3
GO:0071480 cellular response to gamma radiation 1.735337e-3
GO:0006515 misfolded or incompletely synthesized protein catabolic process 1.748262e-3
GO:0046952 ketone body catabolic process 1.811192e-3
GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 1.825595e-3
GO:0007004 telomere maintenance via telomerase 1.826262e-3
GO:0043587 tongue morphogenesis 1.842221e-3
GO:0035752 lysosomal lumen pH elevation 1.850585e-3
GO:0001575 globoside metabolic process 1.850585e-3
GO:0000046 autophagic vacuole fusion 1.850585e-3
GO:0045415 negative regulation of interleukin-8 biosynthetic process 1.914544e-3
GO:0044342 type B pancreatic cell proliferation 1.924256e-3
GO:0010918 positive regulation of mitochondrial membrane potential 1.924256e-3
GO:0051798 positive regulation of hair follicle development 1.931225e-3
GO:0042508 tyrosine phosphorylation of Stat1 protein 1.958367e-3
GO:0051865 protein autoubiquitination 1.964329e-3
GO:0010799 regulation of peptidyl-threonine phosphorylation 1.980061e-3
GO:2000119 negative regulation of sodium-dependent phosphate transport 2.009148e-3
GO:0008295 spermidine biosynthetic process 2.009148e-3
GO:0006563 L-serine metabolic process 2.053135e-3
GO:0007158 neuron cell-cell adhesion 2.065637e-3
GO:0007096 regulation of exit from mitosis 2.098973e-3
GO:0042699 follicle-stimulating hormone signaling pathway 2.107887e-3
GO:0072012 glomerulus vasculature development 2.207164e-3
GO:0016446 somatic hypermutation of immunoglobulin genes 2.227932e-3
GO:0010523 negative regulation of calcium ion transport into cytosol 2.234504e-3
GO:0048483 autonomic nervous system development 2.242882e-3
GO:0006312 mitotic recombination 2.338990e-3
GO:0000725 recombinational repair 2.383150e-3
GO:0015842 synaptic vesicle amine transport 2.399733e-3
GO:0010742 macrophage derived foam cell differentiation 2.423641e-3
GO:0019695 choline metabolic process 2.537663e-3
GO:0021903 rostrocaudal neural tube patterning 2.541345e-3
GO:0006256 UDP catabolic process 2.549424e-3
GO:0060252 positive regulation of glial cell proliferation 2.580199e-3
GO:0032793 positive regulation of CREB transcription factor activity 2.592430e-3
GO:0000724 double-strand break repair via homologous recombination 2.645456e-3
GO:0051298 centrosome duplication 2.664108e-3
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 2.668718e-3
GO:0097116 gephyrin clustering 2.697167e-3
GO:0051968 positive regulation of synaptic transmission, glutamatergic 2.733827e-3
GO:0060631 regulation of meiosis I 2.743282e-3
GO:0032007 negative regulation of TOR signaling cascade 2.771454e-3
GO:0034654 nucleobase-containing compound biosynthetic process 2.772223e-3
GO:0097105 presynaptic membrane assembly 2.779104e-3
GO:0003149 membranous septum morphogenesis 2.882066e-3
GO:0009446 putrescine biosynthetic process 3.034666e-3
GO:0035427 purine nucleoside transmembrane transport 3.034666e-3
GO:0006258 UDP-glucose catabolic process 3.034666e-3
GO:0034241 positive regulation of macrophage fusion 3.072353e-3
GO:0008625 induction of apoptosis via death domain receptors 3.105625e-3
GO:0010157 response to chlorate 3.157912e-3
GO:0030917 midbrain-hindbrain boundary development 3.172105e-3
GO:0010458 exit from mitosis 3.239008e-3
GO:0085029 extracellular matrix assembly 3.253656e-3
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 3.262190e-3
GO:0048210 Golgi vesicle fusion to target membrane 3.264809e-3
GO:0045218 zonula adherens maintenance 3.326490e-3
GO:0030202 heparin metabolic process 3.326490e-3
GO:0060828 regulation of canonical Wnt receptor signaling pathway 3.334052e-3
GO:0006370 mRNA capping 3.341735e-3
GO:0030206 chondroitin sulfate biosynthetic process 3.376331e-3
GO:0052200 response to host defenses 3.397592e-3
GO:0051952 regulation of amine transport 3.438082e-3
GO:0045838 positive regulation of membrane potential 3.488849e-3
GO:0006596 polyamine biosynthetic process 3.488849e-3
GO:0035645 enteric smooth muscle cell differentiation 3.509534e-3
GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 3.581775e-3
GO:0003218 cardiac left ventricle formation 3.614816e-3
GO:0070198 protein localization to chromosome, telomeric region 3.631392e-3
GO:0006325 chromatin organization 3.782261e-3
GO:0034394 protein localization at cell surface 3.788902e-3
GO:0032965 regulation of collagen biosynthetic process 3.798623e-3
GO:0022601 menstrual cycle phase 3.840922e-3
GO:0006275 regulation of DNA replication 3.867749e-3
GO:0008216 spermidine metabolic process 3.875370e-3
GO:0009649 entrainment of circadian clock 3.904932e-3
GO:0002885 positive regulation of hypersensitivity 3.917343e-3
GO:0043029 T cell homeostasis 4.015029e-3
GO:0045682 regulation of epidermis development 4.047095e-3
GO:0071218 cellular response to misfolded protein 4.058440e-3
GO:0097119 postsynaptic density protein 95 clustering 4.154525e-3
GO:0097104 postsynaptic membrane assembly 4.154525e-3
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 4.301538e-3
GO:0006278 RNA-dependent DNA replication 4.320380e-3
GO:0051152 positive regulation of smooth muscle cell differentiation 4.339266e-3
GO:0051926 negative regulation of calcium ion transport 4.516232e-3
GO:0008588 release of cytoplasmic sequestered NF-kappaB 4.570495e-3
GO:2000002 negative regulation of DNA damage checkpoint 4.572033e-3
GO:0021551 central nervous system morphogenesis 4.572033e-3
GO:0070625 zymogen granule exocytosis 4.572033e-3
GO:0022004 midbrain-hindbrain boundary maturation during brain development 4.572033e-3
GO:0021588 cerebellum formation 4.572033e-3
GO:0010982 regulation of high-density lipoprotein particle clearance 4.595659e-3
GO:0031069 hair follicle morphogenesis 4.653945e-3
GO:0019532 oxalate transport 4.738821e-3
GO:0046607 positive regulation of centrosome cycle 4.808121e-3
GO:0006529 asparagine biosynthetic process 4.808121e-3
GO:0016242 negative regulation of macroautophagy 4.808121e-3
GO:0006669 sphinganine-1-phosphate biosynthetic process 4.808121e-3
GO:0010983 positive regulation of high-density lipoprotein particle clearance 4.808121e-3
GO:0016072 rRNA metabolic process 4.893525e-3
GO:0048642 negative regulation of skeletal muscle tissue development 5.019620e-3
GO:0072124 regulation of glomerular mesangial cell proliferation 5.087884e-3
GO:0045604 regulation of epidermal cell differentiation 5.191287e-3
GO:0042149 cellular response to glucose starvation 5.202325e-3
GO:0010536 positive regulation of activation of Janus kinase activity 5.286528e-3
GO:0015904 tetracycline transport 5.294852e-3
GO:0002922 positive regulation of humoral immune response 5.480915e-3
GO:0061205 paramesonephric duct development 5.527449e-3
GO:2000466 negative regulation of glycogen (starch) synthase activity 5.527449e-3
GO:0046501 protoporphyrinogen IX metabolic process 5.527449e-3
GO:0002331 pre-B cell allelic exclusion 5.527449e-3
GO:0007260 tyrosine phosphorylation of STAT protein 5.600166e-3
GO:0000718 nucleotide-excision repair, DNA damage removal 5.601930e-3
GO:0048251 elastic fiber assembly 5.616021e-3
GO:0032910 regulation of transforming growth factor beta3 production 5.653335e-3
GO:0051026 chiasma assembly 5.744625e-3
GO:0000723 telomere maintenance 5.845059e-3
GO:0050434 positive regulation of viral transcription 5.878907e-3
GO:0060290 transdifferentiation 5.960434e-3
GO:0002092 positive regulation of receptor internalization 6.102492e-3
GO:0009247 glycolipid biosynthetic process 6.280387e-3
GO:0009107 lipoate biosynthetic process 6.288492e-3
GO:0016925 protein sumoylation 6.299782e-3
GO:0019388 galactose catabolic process 6.361411e-3
GO:0021933 radial glia guided migration of cerebellar granule cell 6.375390e-3
GO:0070179 D-serine biosynthetic process 6.375390e-3
GO:0006783 heme biosynthetic process 6.380567e-3
GO:0014059 regulation of dopamine secretion 6.416870e-3
GO:0006396 RNA processing 6.544911e-3
GO:0043932 ossification involved in bone remodeling 6.632333e-3
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 6.632333e-3
GO:0033522 histone H2A ubiquitination 6.685215e-3
GO:0051973 positive regulation of telomerase activity 6.720851e-3
GO:0032025 response to cobalt ion 6.720851e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 6.720851e-3
GO:0032801 receptor catabolic process 6.856387e-3
GO:0051788 response to misfolded protein 7.066909e-3
GO:0006166 purine ribonucleoside salvage 7.107913e-3
GO:0090141 positive regulation of mitochondrial fission 7.107913e-3
GO:0006598 polyamine catabolic process 7.107913e-3
GO:0006298 mismatch repair 7.135133e-3
GO:0042796 snRNA transcription from RNA polymerase III promoter 7.202311e-3
GO:0046318 negative regulation of glucosylceramide biosynthetic process 7.202311e-3
GO:0042795 snRNA transcription from RNA polymerase II promoter 7.202311e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 7.202311e-3
GO:0048755 branching morphogenesis of a nerve 7.296241e-3
GO:0046602 regulation of mitotic centrosome separation 7.345535e-3
GO:0046208 spermine catabolic process 7.375879e-3
GO:0061198 fungiform papilla formation 7.449142e-3
GO:0045414 regulation of interleukin-8 biosynthetic process 7.469077e-3
GO:0016570 histone modification 7.519353e-3
GO:0060708 spongiotrophoblast differentiation 7.529394e-3
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 7.572781e-3
GO:0018130 heterocycle biosynthetic process 7.669000e-3
GO:0050764 regulation of phagocytosis 8.123507e-3
GO:0010535 positive regulation of activation of JAK2 kinase activity 8.160560e-3
GO:0051088 PMA-inducible membrane protein ectodomain proteolysis 8.166178e-3
GO:0046039 GTP metabolic process 8.373060e-3
GO:0006525 arginine metabolic process 8.498411e-3
GO:0021555 midbrain-hindbrain boundary morphogenesis 8.510736e-3
GO:0032212 positive regulation of telomere maintenance via telomerase 8.546514e-3
GO:0051873 killing by host of symbiont cells 8.551506e-3
GO:0044246 regulation of multicellular organismal metabolic process 8.589425e-3
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration 8.638465e-3
GO:0010845 positive regulation of reciprocal meiotic recombination 8.638465e-3
GO:0034728 nucleosome organization 8.669974e-3
GO:0032508 DNA duplex unwinding 8.681384e-3
GO:0002891 positive regulation of immunoglobulin mediated immune response 8.684773e-3
GO:0045338 farnesyl diphosphate metabolic process 8.737257e-3
GO:0035518 histone H2A monoubiquitination 8.786777e-3
GO:0051414 response to cortisol stimulus 8.811089e-3
GO:0045843 negative regulation of striated muscle tissue development 8.882880e-3
GO:0033603 positive regulation of dopamine secretion 8.897897e-3
GO:0007007 inner mitochondrial membrane organization 8.897897e-3
GO:0010712 regulation of collagen metabolic process 9.008609e-3
GO:0007497 posterior midgut development 9.014178e-3
GO:0006957 complement activation, alternative pathway 9.042263e-3
GO:0045660 positive regulation of neutrophil differentiation 9.145958e-3
GO:0010994 free ubiquitin chain polymerization 9.280758e-3
GO:0009452 RNA capping 9.330795e-3
GO:0035303 regulation of dephosphorylation 9.399721e-3
GO:0008156 negative regulation of DNA replication 9.433006e-3
GO:0006744 ubiquinone biosynthetic process 9.586625e-3
GO:0032392 DNA geometric change 9.631809e-3
GO:0070172 positive regulation of tooth mineralization 9.658431e-3
GO:0016246 RNA interference 9.671981e-3
GO:0022614 membrane to membrane docking 9.802093e-3
GO:0021759 globus pallidus development 9.809700e-3
GO:0010631 epithelial cell migration 9.840778e-3
GO:0051324 prophase 9.866877e-3
GO:0032075 positive regulation of nuclease activity 1.016344e-2
GO:0000239 pachytene 1.016344e-2
GO:0016578 histone deubiquitination 1.020552e-2
GO:0051454 intracellular pH elevation 1.026450e-2
GO:0006175 dATP biosynthetic process 1.026450e-2
GO:0090161 Golgi ribbon formation 1.051229e-2
GO:0022417 protein maturation by protein folding 1.051229e-2
GO:0007522 visceral muscle development 1.056093e-2
GO:0008215 spermine metabolic process 1.057935e-2
GO:0016188 synaptic vesicle maturation 1.086331e-2
GO:0051095 regulation of helicase activity 1.086750e-2
GO:0034199 activation of protein kinase A activity 1.112046e-2
GO:2000463 positive regulation of excitatory postsynaptic membrane potential 1.115373e-2
GO:2000249 regulation of actin cytoskeleton reorganization 1.118517e-2
GO:2000064 regulation of cortisol biosynthetic process 1.130677e-2
GO:0010760 negative regulation of macrophage chemotaxis 1.148662e-2
GO:0006338 chromatin remodeling 1.155487e-2
GO:0045128 negative regulation of reciprocal meiotic recombination 1.156826e-2
GO:0006311 meiotic gene conversion 1.156826e-2
GO:0042732 D-xylose metabolic process 1.156826e-2
GO:0034498 early endosome to Golgi transport 1.157351e-2
GO:0048313 Golgi inheritance 1.157351e-2
GO:0002017 regulation of blood volume by renal aldosterone 1.157351e-2
GO:0048627 myoblast development 1.169821e-2
GO:0061301 cerebellum vasculature morphogenesis 1.177296e-2
GO:0048596 embryonic camera-type eye morphogenesis 1.178723e-2
GO:0045416 positive regulation of interleukin-8 biosynthetic process 1.191365e-2
GO:0009165 nucleotide biosynthetic process 1.196830e-2
GO:0045994 positive regulation of translational initiation by iron 1.207326e-2
GO:0002037 negative regulation of L-glutamate transport 1.207326e-2
GO:0043097 pyrimidine nucleoside salvage 1.208008e-2
GO:0090130 tissue migration 1.212618e-2
GO:2000378 negative regulation of reactive oxygen species metabolic process 1.214154e-2
GO:0061196 fungiform papilla development 1.231326e-2
GO:0016569 covalent chromatin modification 1.233728e-2
GO:0016573 histone acetylation 1.241747e-2
GO:0050832 defense response to fungus 1.246800e-2
GO:0015671 oxygen transport 1.253437e-2
GO:0033148 positive regulation of estrogen receptor signaling pathway 1.264888e-2
GO:0031647 regulation of protein stability 1.274610e-2
GO:0006184 GTP catabolic process 1.280852e-2
GO:0001825 blastocyst formation 1.281930e-2
GO:0050821 protein stabilization 1.308132e-2
GO:0051255 spindle midzone assembly 1.314895e-2
GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine 1.314895e-2
GO:0032922 circadian regulation of gene expression 1.324717e-2
GO:0072301 regulation of metanephric glomerular mesangial cell proliferation 1.356068e-2
GO:0033128 negative regulation of histone phosphorylation 1.356068e-2
GO:0051303 establishment of chromosome localization 1.368691e-2
GO:0046950 cellular ketone body metabolic process 1.381021e-2
GO:0090140 regulation of mitochondrial fission 1.385382e-2
GO:0048668 collateral sprouting 1.393488e-2
GO:0045426 quinone cofactor biosynthetic process 1.397491e-2
GO:0031943 regulation of glucocorticoid metabolic process 1.405716e-2
GO:0010889 regulation of sequestering of triglyceride 1.420011e-2
GO:0006348 chromatin silencing at telomere 1.420130e-2
GO:2000300 regulation of synaptic vesicle exocytosis 1.445613e-2
GO:0009301 snRNA transcription 1.459082e-2
GO:0048771 tissue remodeling 1.462981e-2
GO:0060620 regulation of cholesterol import 1.466135e-2
GO:0046034 ATP metabolic process 1.508902e-2
GO:0061100 lung neuroendocrine cell differentiation 1.515335e-2
GO:0061102 stomach neuroendocrine cell differentiation 1.515335e-2
GO:0071259 cellular response to magnetism 1.515335e-2
GO:0061104 adrenal chromaffin cell differentiation 1.515335e-2
GO:0061103 carotid body glomus cell differentiation 1.515335e-2
GO:0060165 regulation of timing of subpallium neuron differentiation 1.515335e-2
GO:0060163 subpallium neuron fate commitment 1.515335e-2
GO:0007079 mitotic chromosome movement towards spindle pole 1.515335e-2
GO:0003359 noradrenergic neuron fate commitment 1.515335e-2
GO:0007400 neuroblast fate determination 1.515335e-2
GO:0019448 L-cysteine catabolic process 1.516598e-2
GO:0044336 canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis 1.521927e-2
GO:0045104 intermediate filament cytoskeleton organization 1.524202e-2
GO:0060337 type I interferon-mediated signaling pathway 1.533188e-2
GO:0034619 cellular chaperone-mediated protein complex assembly 1.554514e-2
GO:0070585 protein localization in mitochondrion 1.562394e-2
GO:0006474 N-terminal protein amino acid acetylation 1.570371e-2
GO:0070213 protein auto-ADP-ribosylation 1.573559e-2
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA 1.581130e-2
GO:0034453 microtubule anchoring 1.584950e-2
GO:0032069 regulation of nuclease activity 1.586084e-2
GO:0030262 apoptotic nuclear change 1.597875e-2
GO:0007143 female meiosis 1.609684e-2
GO:0015669 gas transport 1.621694e-2
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.628224e-2
GO:0033602 negative regulation of dopamine secretion 1.629873e-2
GO:0060816 random inactivation of X chromosome 1.631964e-2
GO:0060220 camera-type eye photoreceptor cell fate commitment 1.631964e-2


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0034382 chylomicron remnant clearance 1.848597e-14
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 3.233617e-12
GO:0010985 negative regulation of lipoprotein particle clearance 5.259956e-12
GO:0010984 regulation of lipoprotein particle clearance 7.568254e-12
GO:0045717 negative regulation of fatty acid biosynthetic process 7.170882e-11
GO:0006538 glutamate catabolic process 7.235135e-11
GO:0045922 negative regulation of fatty acid metabolic process 1.268734e-10
GO:0006184 GTP catabolic process 1.348673e-10
GO:0051005 negative regulation of lipoprotein lipase activity 2.211295e-10
GO:0031536 positive regulation of exit from mitosis 3.611213e-10
GO:0046039 GTP metabolic process 5.637446e-10
GO:0045806 negative regulation of endocytosis 4.693199e-9
GO:0009817 defense response to fungus, incompatible interaction 7.567166e-9
GO:0008608 attachment of spindle microtubules to kinetochore 7.728378e-9
GO:0032488 Cdc42 protein signal transduction 2.078149e-8
GO:0031507 heterochromatin formation 2.493860e-8
GO:0060192 negative regulation of lipase activity 2.564929e-8
GO:0010987 negative regulation of high-density lipoprotein particle clearance 7.317476e-8
GO:0010897 negative regulation of triglyceride catabolic process 7.317476e-8
GO:0010982 regulation of high-density lipoprotein particle clearance 7.759198e-8
GO:0006540 glutamate decarboxylation to succinate 1.002811e-7
GO:0006656 phosphatidylcholine biosynthetic process 1.004044e-7
GO:0051055 negative regulation of lipid biosynthetic process 1.026735e-7
GO:0006139 nucleobase-containing compound metabolic process 1.357280e-7
GO:0042254 ribosome biogenesis 1.551927e-7
GO:0002513 tolerance induction to self antigen 1.655317e-7
GO:0016032 viral reproduction 1.681178e-7
GO:0050995 negative regulation of lipid catabolic process 1.761202e-7
GO:0048261 negative regulation of receptor-mediated endocytosis 1.881593e-7
GO:0034470 ncRNA processing 1.954841e-7
GO:0031508 centromeric heterochromatin formation 2.103748e-7
GO:0010989 negative regulation of low-density lipoprotein particle clearance 2.118948e-7
GO:0007096 regulation of exit from mitosis 2.634607e-7
GO:0016072 rRNA metabolic process 5.087920e-7
GO:0010467 gene expression 5.419118e-7
GO:0034447 very-low-density lipoprotein particle clearance 6.641648e-7
GO:0033239 negative regulation of cellular amine metabolic process 7.808592e-7
GO:0045833 negative regulation of lipid metabolic process 7.868903e-7
GO:0010936 negative regulation of macrophage cytokine production 8.995799e-7
GO:0045046 protein import into peroxisome membrane 1.007109e-6
GO:0002536 respiratory burst involved in inflammatory response 1.106069e-6
GO:0009082 branched chain family amino acid biosynthetic process 1.250807e-6
GO:0010900 negative regulation of phosphatidylcholine catabolic process 1.250807e-6
GO:0050713 negative regulation of interleukin-1 beta secretion 1.262688e-6
GO:0034641 cellular nitrogen compound metabolic process 1.847002e-6
GO:0071173 spindle assembly checkpoint 2.113132e-6
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 2.256808e-6
GO:0031577 spindle checkpoint 3.450252e-6
GO:0044249 cellular biosynthetic process 3.739506e-6
GO:0033700 phospholipid efflux 3.792648e-6
GO:0007406 negative regulation of neuroblast proliferation 4.059509e-6
GO:0090304 nucleic acid metabolic process 4.792990e-6
GO:0006807 nitrogen compound metabolic process 4.915588e-6
GO:0007224 smoothened signaling pathway 5.034668e-6
GO:0016075 rRNA catabolic process 5.911791e-6
GO:0060390 regulation of SMAD protein import into nucleus 7.473644e-6
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 8.237488e-6
GO:0051028 mRNA transport 8.277626e-6
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine 8.564116e-6
GO:0048298 positive regulation of isotype switching to IgA isotypes 8.966023e-6
GO:0050658 RNA transport 9.101505e-6
GO:0000075 cell cycle checkpoint 9.229219e-6
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 9.763007e-6
GO:0044260 cellular macromolecule metabolic process 1.077736e-5
GO:0034660 ncRNA metabolic process 1.277255e-5
GO:0002719 negative regulation of cytokine production involved in immune response 1.364882e-5
GO:0043932 ossification involved in bone remodeling 1.427536e-5
GO:0006536 glutamate metabolic process 1.484701e-5
GO:0051313 attachment of spindle microtubules to chromosome 1.655789e-5
GO:0061136 regulation of proteasomal protein catabolic process 1.714817e-5
GO:0015931 nucleobase-containing compound transport 1.834275e-5
GO:0032375 negative regulation of cholesterol transport 1.845505e-5
GO:0014043 negative regulation of neuron maturation 1.864570e-5
GO:0050711 negative regulation of interleukin-1 secretion 1.897320e-5
GO:0060391 positive regulation of SMAD protein import into nucleus 2.067430e-5
GO:0002701 negative regulation of production of molecular mediator of immune response 2.084370e-5
GO:0070508 cholesterol import 2.242194e-5
GO:0051340 regulation of ligase activity 2.421038e-5
GO:0051788 response to misfolded protein 2.463401e-5
GO:0060433 bronchus development 2.524917e-5
GO:0071843 cellular component biogenesis at cellular level 2.667715e-5
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 2.822483e-5
GO:0046814 virion attachment, binding of host cell surface coreceptor 3.076156e-5
GO:0019064 viral envelope fusion with host membrane 3.076156e-5
GO:0034380 high-density lipoprotein particle assembly 3.098983e-5
GO:0006657 CDP-choline pathway 3.374581e-5
GO:0006364 rRNA processing 3.573988e-5
GO:0050768 negative regulation of neurogenesis 3.604910e-5
GO:0006646 phosphatidylethanolamine biosynthetic process 3.617326e-5
GO:0043537 negative regulation of blood vessel endothelial cell migration 3.667668e-5
GO:0046670 positive regulation of retinal cell programmed cell death 3.791021e-5
GO:0046452 dihydrofolate metabolic process 3.791021e-5
GO:0002525 acute inflammatory response to non-antigenic stimulus 3.791021e-5
GO:0009067 aspartate family amino acid biosynthetic process 3.948572e-5
GO:0009207 purine ribonucleoside triphosphate catabolic process 4.143703e-5
GO:0016557 peroxisome membrane biogenesis 4.279293e-5
GO:0051438 regulation of ubiquitin-protein ligase activity 4.332150e-5
GO:0007212 dopamine receptor signaling pathway 4.628888e-5
GO:0060696 regulation of phospholipid catabolic process 4.894813e-5
GO:2000178 negative regulation of neural precursor cell proliferation 4.953119e-5
GO:0033084 regulation of immature T cell proliferation in thymus 5.254941e-5
GO:0009146 purine nucleoside triphosphate catabolic process 5.495161e-5
GO:0090343 positive regulation of cell aging 5.625086e-5
GO:0032465 regulation of cytokinesis 5.757687e-5
GO:0045541 negative regulation of cholesterol biosynthetic process 6.537274e-5
GO:0006403 RNA localization 6.785264e-5
GO:0060621 negative regulation of cholesterol import 6.872134e-5
GO:0033344 cholesterol efflux 7.134583e-5
GO:0009065 glutamine family amino acid catabolic process 7.193348e-5
GO:0046474 glycerophospholipid biosynthetic process 7.549699e-5
GO:0018243 protein O-linked glycosylation via threonine 7.554333e-5
GO:0018242 protein O-linked glycosylation via serine 7.554333e-5
GO:0022613 ribonucleoprotein complex biogenesis 7.748324e-5
GO:0008652 cellular amino acid biosynthetic process 8.378917e-5
GO:0071156 regulation of cell cycle arrest 8.862150e-5
GO:0019550 glutamate catabolic process to aspartate 9.019161e-5
GO:0019551 glutamate catabolic process to 2-oxoglutarate 9.019161e-5
GO:0006533 aspartate catabolic process 9.019161e-5
GO:0006532 aspartate biosynthetic process 9.019161e-5
GO:0008033 tRNA processing 9.189310e-5
GO:0035307 positive regulation of protein dephosphorylation 9.374132e-5
GO:0021539 subthalamus development 9.892275e-5
GO:0009143 nucleoside triphosphate catabolic process 1.006751e-4
GO:0044237 cellular metabolic process 1.102486e-4
GO:0035306 positive regulation of dephosphorylation 1.114634e-4
GO:0051926 negative regulation of calcium ion transport 1.260440e-4
GO:0051351 positive regulation of ligase activity 1.260440e-4
GO:0009261 ribonucleotide catabolic process 1.270279e-4
GO:0071712 ER-associated misfolded protein catabolic process 1.273191e-4
GO:0032915 positive regulation of transforming growth factor beta2 production 1.273191e-4
GO:0090307 spindle assembly involved in mitosis 1.313188e-4
GO:0043163 cell envelope organization 1.314170e-4
GO:0009154 purine ribonucleotide catabolic process 1.318549e-4
GO:0033083 regulation of immature T cell proliferation 1.323971e-4
GO:0045862 positive regulation of proteolysis 1.365428e-4
GO:0019049 evasion of host defenses by virus 1.408973e-4
GO:0070286 axonemal dynein complex assembly 1.454773e-4
GO:0033088 negative regulation of immature T cell proliferation in thymus 1.454773e-4
GO:0060439 trachea morphogenesis 1.523933e-4
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 1.566777e-4
GO:0048259 regulation of receptor-mediated endocytosis 1.724443e-4
GO:0018206 peptidyl-methionine modification 1.748765e-4
GO:0045839 negative regulation of mitosis 1.854749e-4
GO:0051443 positive regulation of ubiquitin-protein ligase activity 1.900240e-4
GO:0051004 regulation of lipoprotein lipase activity 1.912076e-4
GO:0045123 cellular extravasation 1.918139e-4
GO:0043623 cellular protein complex assembly 1.956880e-4
GO:0050765 negative regulation of phagocytosis 1.987574e-4
GO:0016567 protein ubiquitination 1.991419e-4
GO:0006868 glutamine transport 2.017399e-4
GO:0060438 trachea development 2.062499e-4
GO:0021871 forebrain regionalization 2.104226e-4
GO:0016070 RNA metabolic process 2.115584e-4
GO:0060620 regulation of cholesterol import 2.120782e-4
GO:0048368 lateral mesoderm development 2.120782e-4
GO:0051322 anaphase 2.120782e-4
GO:0045210 FasL biosynthetic process 2.298554e-4
GO:0001935 endothelial cell proliferation 2.307231e-4
GO:0043508 negative regulation of JUN kinase activity 2.407970e-4
GO:0018202 peptidyl-histidine modification 2.463070e-4
GO:0009199 ribonucleoside triphosphate metabolic process 2.466306e-4
GO:0008635 activation of caspase activity by cytochrome c 2.560087e-4
GO:0000733 DNA strand renaturation 2.744996e-4
GO:0033599 regulation of mammary gland epithelial cell proliferation 2.759721e-4
GO:0006713 glucocorticoid catabolic process 2.796881e-4
GO:0071636 positive regulation of transforming growth factor beta production 2.866025e-4
GO:0070979 protein K11-linked ubiquitination 2.872406e-4
GO:0000087 M phase of mitotic cell cycle 2.888051e-4
GO:0021933 radial glia guided migration of cerebellar granule cell 2.904389e-4
GO:0051315 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 2.914590e-4
GO:0034645 cellular macromolecule biosynthetic process 2.948068e-4
GO:0031055 chromatin remodeling at centromere 3.074165e-4
GO:0009205 purine ribonucleoside triphosphate metabolic process 3.120679e-4
GO:0021997 neural plate axis specification 3.220308e-4
GO:0042256 mature ribosome assembly 3.234183e-4
GO:0006531 aspartate metabolic process 3.234183e-4
GO:0006654 phosphatidic acid biosynthetic process 3.370696e-4
GO:0009309 amine biosynthetic process 3.421775e-4
GO:0070193 synaptonemal complex organization 3.450585e-4
GO:0048596 embryonic camera-type eye morphogenesis 3.507945e-4
GO:0045599 negative regulation of fat cell differentiation 3.577222e-4
GO:0021532 neural tube patterning 3.663559e-4
GO:0045778 positive regulation of ossification 3.730191e-4
GO:0051099 positive regulation of binding 3.730271e-4
GO:0008054 cyclin catabolic process 3.776015e-4
GO:0030202 heparin metabolic process 3.883739e-4
GO:0032446 protein modification by small protein conjugation 3.945558e-4
GO:0035024 negative regulation of Rho protein signal transduction 4.306562e-4
GO:0001573 ganglioside metabolic process 4.383864e-4
GO:0042136 neurotransmitter biosynthetic process 4.483176e-4
GO:0031396 regulation of protein ubiquitination 4.505355e-4
GO:0061072 iris morphogenesis 4.553452e-4
GO:0072205 metanephric collecting duct development 4.608999e-4
GO:0006999 nuclear pore organization 4.628643e-4
GO:0006106 fumarate metabolic process 4.700786e-4
GO:0000060 protein import into nucleus, translocation 4.735682e-4
GO:0031398 positive regulation of protein ubiquitination 4.808518e-4
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 4.876302e-4
GO:0060744 mammary gland branching involved in thelarche 4.977088e-4
GO:0035066 positive regulation of histone acetylation 5.009856e-4
GO:0006913 nucleocytoplasmic transport 5.177998e-4
GO:0042360 vitamin E metabolic process 5.375284e-4
GO:0051169 nuclear transport 5.399260e-4
GO:0006457 protein folding 5.405305e-4
GO:0001755 neural crest cell migration 5.592899e-4
GO:0031575 mitotic cell cycle G1/S transition checkpoint 5.713968e-4
GO:0031076 embryonic camera-type eye development 5.824145e-4
GO:0071218 cellular response to misfolded protein 6.010038e-4
GO:0007067 mitosis 6.043014e-4
GO:0010721 negative regulation of cell development 6.247437e-4
GO:0060461 right lung morphogenesis 6.477900e-4
GO:0090131 mesenchyme migration 6.477900e-4
GO:0060446 branching involved in open tracheal system development 6.477900e-4
GO:0048613 embryonic ectodermal digestive tract morphogenesis 6.477900e-4
GO:0048371 lateral mesodermal cell differentiation 6.477900e-4
GO:0014822 detection of wounding 6.477900e-4
GO:0051168 nuclear export 6.529002e-4
GO:0042772 DNA damage response, signal transduction resulting in transcription 6.565692e-4
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 6.583811e-4
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 6.696617e-4
GO:0007093 mitotic cell cycle checkpoint 6.809059e-4
GO:0035645 enteric smooth muscle cell differentiation 7.180126e-4
GO:0030719 P granule organization 7.180126e-4
GO:0000395 nuclear mRNA 5'-splice site recognition 7.180126e-4
GO:0007497 posterior midgut development 7.180126e-4
GO:0007052 mitotic spindle organization 7.729056e-4
GO:0060364 frontal suture morphogenesis 7.769704e-4
GO:0006195 purine nucleotide catabolic process 7.874904e-4
GO:0008354 germ cell migration 7.885491e-4
GO:0009144 purine nucleoside triphosphate metabolic process 8.624828e-4
GO:0009259 ribonucleotide metabolic process 8.635211e-4
GO:0045629 negative regulation of T-helper 2 cell differentiation 8.657730e-4
GO:0031365 N-terminal protein amino acid modification 8.747924e-4
GO:0006555 methionine metabolic process 8.747924e-4
GO:0060020 Bergmann glial cell differentiation 8.802816e-4
GO:0060535 trachea cartilage morphogenesis 8.828940e-4
GO:0009141 nucleoside triphosphate metabolic process 9.274236e-4
GO:0046639 negative regulation of alpha-beta T cell differentiation 9.379588e-4
GO:0033238 regulation of cellular amine metabolic process 9.500873e-4
GO:0008208 C21-steroid hormone catabolic process 9.538797e-4
GO:0035315 hair cell differentiation 9.538797e-4
GO:0006611 protein export from nucleus 9.576130e-4
GO:0007569 cell aging 9.929936e-4
GO:0021546 rhombomere development 1.014160e-3
GO:0051693 actin filament capping 1.030220e-3
GO:0072061 inner medullary collecting duct development 1.031009e-3
GO:0072060 outer medullary collecting duct development 1.031009e-3
GO:0016332 establishment or maintenance of polarity of embryonic epithelium 1.031009e-3
GO:0006664 glycolipid metabolic process 1.043909e-3
GO:0010994 free ubiquitin chain polymerization 1.085738e-3
GO:0032092 positive regulation of protein binding 1.087134e-3
GO:0071841 cellular component organization or biogenesis at cellular level 1.088730e-3
GO:0001555 oocyte growth 1.094409e-3
GO:0030382 sperm mitochondrion organization 1.094409e-3
GO:0021978 telencephalon regionalization 1.095421e-3
GO:0044238 primary metabolic process 1.104885e-3
GO:0022415 viral reproductive process 1.130044e-3
GO:0006344 maintenance of chromatin silencing 1.220499e-3
GO:0006687 glycosphingolipid metabolic process 1.239155e-3
GO:0010596 negative regulation of endothelial cell migration 1.277053e-3
GO:0042443 phenylethylamine metabolic process 1.300554e-3
GO:0018125 peptidyl-cysteine methylation 1.300554e-3
GO:0002418 immune response to tumor cell 1.300554e-3
GO:0051225 spindle assembly 1.308427e-3
GO:0060534 trachea cartilage development 1.309883e-3
GO:0043170 macromolecule metabolic process 1.332553e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.339418e-3
GO:0090403 oxidative stress-induced premature senescence 1.339595e-3
GO:0007094 mitotic cell cycle spindle assembly checkpoint 1.339595e-3
GO:0051016 barbed-end actin filament capping 1.339595e-3
GO:0060033 anatomical structure regression 1.414009e-3
GO:0070925 organelle assembly 1.414260e-3
GO:0060458 right lung development 1.447239e-3
GO:0006398 histone mRNA 3'-end processing 1.447239e-3
GO:0009059 macromolecule biosynthetic process 1.465460e-3
GO:0009058 biosynthetic process 1.467644e-3
GO:0009166 nucleotide catabolic process 1.487705e-3
GO:0006780 uroporphyrinogen III biosynthetic process 1.504791e-3
GO:0035582 negative regulation of BMP signaling pathway by extracellular sequestering of BMP 1.504791e-3
GO:0017196 N-terminal peptidyl-methionine acetylation 1.504791e-3
GO:0090209 negative regulation of triglyceride metabolic process 1.520039e-3
GO:0009086 methionine biosynthetic process 1.520039e-3
GO:0060762 regulation of branching involved in mammary gland duct morphogenesis 1.520039e-3
GO:0007130 synaptonemal complex assembly 1.536229e-3
GO:0006396 RNA processing 1.547228e-3
GO:0007435 salivary gland morphogenesis 1.547805e-3
GO:0008156 negative regulation of DNA replication 1.661590e-3
GO:0042866 pyruvate biosynthetic process 1.661727e-3
GO:0071174 mitotic cell cycle spindle checkpoint 1.671392e-3
GO:0035426 extracellular matrix-cell signaling 1.715787e-3
GO:0016574 histone ubiquitination 1.721744e-3
GO:0030259 lipid glycosylation 1.780492e-3
GO:0009150 purine ribonucleotide metabolic process 1.795485e-3
GO:0031570 DNA integrity checkpoint 1.801284e-3
GO:0032369 negative regulation of lipid transport 1.812841e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 1.817146e-3
GO:0014032 neural crest cell development 1.884203e-3
GO:0072523 purine-containing compound catabolic process 1.904573e-3
GO:0060136 embryonic process involved in female pregnancy 1.907294e-3
GO:0046394 carboxylic acid biosynthetic process 1.923118e-3
GO:0060363 cranial suture morphogenesis 1.962674e-3
GO:0010896 regulation of triglyceride catabolic process 1.962674e-3
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.990105e-3
GO:0016098 monoterpenoid metabolic process 1.990105e-3
GO:0031427 response to methotrexate 1.990105e-3
GO:0060482 lobar bronchus development 2.012461e-3
GO:0010310 regulation of hydrogen peroxide metabolic process 2.012461e-3
GO:2000774 positive regulation of cellular senescence 2.038137e-3
GO:0035986 senescence-associated heterochromatin focus formation 2.038137e-3
GO:0090402 oncogene-induced senescence 2.038137e-3
GO:0001829 trophectodermal cell differentiation 2.070165e-3
GO:0006302 double-strand break repair 2.081020e-3
GO:0046470 phosphatidylcholine metabolic process 2.095188e-3
GO:0042304 regulation of fatty acid biosynthetic process 2.110922e-3
GO:0006351 transcription, DNA-dependent 2.133637e-3
GO:0070723 response to cholesterol 2.154950e-3
GO:0090311 regulation of protein deacetylation 2.178615e-3
GO:0070370 cellular heat acclimation 2.224992e-3
GO:0045685 regulation of glial cell differentiation 2.229675e-3
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 2.252922e-3
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 2.252922e-3
GO:0043316 cytotoxic T cell degranulation 2.255187e-3
GO:0000279 M phase 2.255905e-3
GO:0043535 regulation of blood vessel endothelial cell migration 2.335053e-3
GO:0021903 rostrocaudal neural tube patterning 2.371548e-3
GO:0006368 transcription elongation from RNA polymerase II promoter 2.387780e-3
GO:0060686 negative regulation of prostatic bud formation 2.387780e-3
GO:0044091 membrane biogenesis 2.451744e-3
GO:0045077 negative regulation of interferon-gamma biosynthetic process 2.454688e-3
GO:0018199 peptidyl-glutamine modification 2.454688e-3
GO:0000077 DNA damage checkpoint 2.454729e-3
GO:0030260 entry into host cell 2.478230e-3
GO:2000045 regulation of G1/S transition of mitotic cell cycle 2.504301e-3
GO:0007431 salivary gland development 2.526352e-3
GO:0010458 exit from mitosis 2.542224e-3
GO:0048312 intracellular distribution of mitochondria 2.544074e-3
GO:0046599 regulation of centriole replication 2.544074e-3
GO:0045581 negative regulation of T cell differentiation 2.562163e-3
GO:0032774 RNA biosynthetic process 2.590673e-3
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 2.593088e-3
GO:0090312 positive regulation of protein deacetylation 2.603565e-3
GO:0090399 replicative senescence 2.608806e-3
GO:0009064 glutamine family amino acid metabolic process 2.772971e-3
GO:0060445 branching involved in salivary gland morphogenesis 2.906555e-3
GO:0072012 glomerulus vasculature development 2.919121e-3
GO:0031063 regulation of histone deacetylation 2.941533e-3
GO:0034655 nucleobase-containing compound catabolic process 2.948778e-3
GO:0008334 histone mRNA metabolic process 2.969027e-3
GO:0071779 G1/S transition checkpoint 3.015940e-3
GO:0042130 negative regulation of T cell proliferation 3.096177e-3
GO:0006975 DNA damage induced protein phosphorylation 3.116308e-3
GO:0072044 collecting duct development 3.117744e-3
GO:0010950 positive regulation of endopeptidase activity 3.126073e-3
GO:0000090 mitotic anaphase 3.126073e-3
GO:0032287 peripheral nervous system myelin maintenance 3.185246e-3
GO:0072104 glomerular capillary formation 3.213997e-3
GO:0030917 midbrain-hindbrain boundary development 3.282241e-3
GO:0014031 mesenchymal cell development 3.284984e-3
GO:0046939 nucleotide phosphorylation 3.349860e-3
GO:0014041 regulation of neuron maturation 3.411571e-3
GO:0072428 signal transduction involved in intra-S DNA damage checkpoint 3.496219e-3
GO:0002357 defense response to tumor cell 3.496219e-3
GO:0021930 cerebellar granule cell precursor proliferation 3.515413e-3
GO:0071394 cellular response to testosterone stimulus 3.515413e-3
GO:0021660 rhombomere 3 formation 3.515413e-3
GO:0021666 rhombomere 5 formation 3.515413e-3
GO:0021555 midbrain-hindbrain boundary morphogenesis 3.515653e-3
GO:0034661 ncRNA catabolic process 3.531426e-3
GO:0051150 regulation of smooth muscle cell differentiation 3.563164e-3
GO:0031065 positive regulation of histone deacetylation 3.607641e-3
GO:0009303 rRNA transcription 3.607641e-3
GO:0048048 embryonic eye morphogenesis 3.640774e-3
GO:0006642 triglyceride mobilization 3.655150e-3
GO:0046700 heterocycle catabolic process 3.671736e-3
GO:0045620 negative regulation of lymphocyte differentiation 3.693916e-3
GO:0060751 branch elongation involved in mammary gland duct branching 3.722775e-3
GO:0014033 neural crest cell differentiation 3.722794e-3
GO:0001777 T cell homeostatic proliferation 3.727466e-3
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 3.757649e-3
GO:0006601 creatine biosynthetic process 3.782652e-3
GO:0046502 uroporphyrinogen III metabolic process 3.782652e-3
GO:0071422 succinate transmembrane transport 3.782652e-3
GO:0033590 response to cobalamin 3.782652e-3
GO:0030501 positive regulation of bone mineralization 3.788130e-3
GO:0021993 initiation of neural tube closure 3.825101e-3
GO:0046718 entry of virus into host cell 3.882239e-3
GO:0010498 proteasomal protein catabolic process 3.895499e-3
GO:0034381 plasma lipoprotein particle clearance 3.928110e-3
GO:0060389 pathway-restricted SMAD protein phosphorylation 3.993608e-3
GO:0001569 patterning of blood vessels 3.999340e-3
GO:0006281 DNA repair 4.003435e-3
GO:0090342 regulation of cell aging 4.021892e-3
GO:0032509 endosome transport via multivesicular body sorting pathway 4.220290e-3
GO:0032467 positive regulation of cytokinesis 4.279761e-3
GO:0032367 intracellular cholesterol transport 4.293897e-3
GO:0010824 regulation of centrosome duplication 4.418187e-3
GO:0002739 regulation of cytokine secretion involved in immune response 4.420838e-3
GO:0010873 positive regulation of cholesterol esterification 4.558745e-3
GO:0046580 negative regulation of Ras protein signal transduction 4.631299e-3
GO:0048285 organelle fission 4.713742e-3
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 4.760215e-3
GO:0060644 mammary gland epithelial cell differentiation 4.769557e-3
GO:0021520 spinal cord motor neuron cell fate specification 4.820352e-3
GO:0072040 negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis 4.867778e-3
GO:0070169 positive regulation of biomineral tissue development 4.946040e-3
GO:0034377 plasma lipoprotein particle assembly 4.984335e-3
GO:0070534 protein K63-linked ubiquitination 4.986411e-3
GO:0051129 negative regulation of cellular component organization 5.008777e-3
GO:0003350 pulmonary myocardium development 5.098384e-3
GO:0090273 regulation of somatostatin secretion 5.100461e-3
GO:0090075 relaxation of muscle 5.299586e-3
GO:0072203 cell proliferation involved in metanephros development 5.357952e-3
GO:0050901 leukocyte tethering or rolling 5.357952e-3
GO:0070179 D-serine biosynthetic process 5.395122e-3
GO:0035674 tricarboxylic acid transmembrane transport 5.395122e-3
GO:0046636 negative regulation of alpha-beta T cell activation 5.533867e-3
GO:0071577 zinc ion transmembrane transport 5.547742e-3
GO:0019048 virus-host interaction 5.553469e-3
GO:0032785 negative regulation of transcription elongation, DNA-dependent 5.604528e-3
GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development 5.606815e-3
GO:0048597 post-embryonic camera-type eye morphogenesis 5.606815e-3
GO:0042713 sperm ejaculation 5.606815e-3
GO:0045017 glycerolipid biosynthetic process 5.638756e-3
GO:0019059 initiation of viral infection 5.694988e-3
GO:0048014 Tie receptor signaling pathway 5.694988e-3
GO:0009083 branched chain family amino acid catabolic process 5.748426e-3
GO:0051058 negative regulation of small GTPase mediated signal transduction 5.805023e-3
GO:0048352 paraxial mesoderm structural organization 5.807656e-3
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 5.807656e-3
GO:0021998 neural plate mediolateral regionalization 5.807656e-3
GO:0021797 forebrain anterior/posterior pattern specification 5.867124e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 5.890122e-3
GO:0021658 rhombomere 3 morphogenesis 5.986756e-3
GO:0021568 rhombomere 2 development 5.986756e-3
GO:0045793 positive regulation of cell size 6.021143e-3
GO:0051152 positive regulation of smooth muscle cell differentiation 6.042251e-3
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 6.073313e-3
GO:0030835 negative regulation of actin filament depolymerization 6.073466e-3
GO:0000281 cytokinesis after mitosis 6.086088e-3
GO:0048762 mesenchymal cell differentiation 6.140958e-3
GO:0007521 muscle cell fate determination 6.336613e-3
GO:0046784 intronless viral mRNA export from host nucleus 6.414535e-3
GO:0030834 regulation of actin filament depolymerization 6.635557e-3
GO:0051865 protein autoubiquitination 6.694843e-3
GO:0060485 mesenchyme development 6.853904e-3
GO:0006354 transcription elongation, DNA-dependent 6.999495e-3
GO:0048311 mitochondrion distribution 7.074224e-3
GO:0009396 folic acid-containing compound biosynthetic process 7.074224e-3
GO:0055118 negative regulation of cardiac muscle contraction 7.178397e-3
GO:0043538 regulation of actin phosphorylation 7.314352e-3
GO:0035865 cellular response to potassium ion 7.314352e-3
GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity 7.314352e-3
GO:0090212 negative regulation of establishment of blood-brain barrier 7.314352e-3
GO:0055107 Golgi to secretory granule transport 7.314352e-3
GO:0016140 O-glycoside metabolic process 7.314352e-3
GO:0006256 UDP catabolic process 7.314352e-3
GO:0009236 cobalamin biosynthetic process 7.314352e-3
GO:0015969 guanosine tetraphosphate metabolic process 7.314352e-3
GO:0035750 protein localization to myelin sheath abaxonal region 7.314352e-3
GO:0034651 cortisol biosynthetic process 7.314352e-3
GO:0015804 neutral amino acid transport 7.339535e-3
GO:0032332 positive regulation of chondrocyte differentiation 7.439380e-3
GO:0006515 misfolded or incompletely synthesized protein catabolic process 7.457190e-3
GO:0042637 catagen 7.457190e-3
GO:0035195 gene silencing by miRNA 7.566956e-3
GO:0032916 positive regulation of transforming growth factor beta3 production 7.601355e-3
GO:0001880 Mullerian duct regression 7.618806e-3
GO:0072054 renal outer medulla development 7.618806e-3
GO:0006399 tRNA metabolic process 7.623634e-3
GO:0070509 calcium ion import 7.683871e-3
GO:0007089 traversing start control point of mitotic cell cycle 7.737204e-3
GO:2000173 negative regulation of branching morphogenesis of a nerve 7.737204e-3
GO:0014842 regulation of satellite cell proliferation 7.737204e-3
GO:0048213 Golgi vesicle prefusion complex stabilization 8.028652e-3
GO:0002542 Factor XII activation 8.028652e-3
GO:0010793 regulation of mRNA export from nucleus 8.028652e-3
GO:0051170 nuclear import 8.048158e-3
GO:0034375 high-density lipoprotein particle remodeling 8.101189e-3
GO:0061311 cell surface receptor linked signaling pathway involved in heart development 8.363616e-3
GO:0048562 embryonic organ morphogenesis 8.414963e-3
GO:0007398 ectoderm development 8.415730e-3
GO:0050868 negative regulation of T cell activation 8.419184e-3
GO:0002679 respiratory burst involved in defense response 8.449937e-3
GO:0060659 nipple sheath formation 8.621159e-3
GO:0061301 cerebellum vasculature morphogenesis 8.621159e-3
GO:0060649 mammary gland bud elongation 8.621159e-3
GO:0055089 fatty acid homeostasis 8.625766e-3
GO:0034508 centromere complex assembly 8.625766e-3
GO:0002740 negative regulation of cytokine secretion involved in immune response 8.749853e-3
GO:0032218 riboflavin transport 8.834859e-3
GO:0043248 proteasome assembly 8.942773e-3
GO:0042482 positive regulation of odontogenesis 8.942773e-3
GO:0007028 cytoplasm organization 8.942773e-3
GO:0072053 renal inner medulla development 9.059169e-3
GO:0043366 beta selection 9.059169e-3
GO:0048050 post-embryonic eye morphogenesis 9.059169e-3
GO:0001574 ganglioside biosynthetic process 9.306674e-3
GO:0007422 peripheral nervous system development 9.310250e-3
GO:0021932 hindbrain radial glia guided cell migration 9.355669e-3
GO:0048484 enteric nervous system development 9.392336e-3