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Novel motif:70

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name:motif70_MAATCGC

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0090304 nucleic acid metabolic process 4.035764e-13
GO:0046755 non-lytic virus budding 9.082867e-12
GO:0006302 double-strand break repair 2.892207e-11
GO:0006313 transposition, DNA-mediated 3.249451e-10
GO:0006103 2-oxoglutarate metabolic process 1.002081e-9
GO:0016070 RNA metabolic process 1.016977e-8
GO:0031503 protein complex localization 1.128223e-8
GO:0010467 gene expression 1.905840e-8
GO:0033566 gamma-tubulin complex localization 4.414252e-8
GO:0032774 RNA biosynthetic process 5.775564e-8
GO:0034629 cellular protein complex localization 7.816715e-8
GO:0006139 nucleobase-containing compound metabolic process 7.966447e-8
GO:0051321 meiotic cell cycle 1.352623e-7
GO:0048291 isotype switching to IgG isotypes 2.239522e-7
GO:0009436 glyoxylate catabolic process 2.239522e-7
GO:0002368 B cell cytokine production 2.239522e-7
GO:0002842 positive regulation of T cell mediated immune response to tumor cell 2.239522e-7
GO:0006457 protein folding 2.795545e-7
GO:0044260 cellular macromolecule metabolic process 2.866908e-7
GO:0070669 response to interleukin-2 3.043525e-7
GO:0034641 cellular nitrogen compound metabolic process 3.073457e-7
GO:0006807 nitrogen compound metabolic process 3.341484e-7
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 3.385754e-7
GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport 3.438300e-7
GO:0006351 transcription, DNA-dependent 3.706294e-7
GO:0000416 positive regulation of histone H3-K36 methylation 4.412405e-7
GO:0060839 endothelial cell fate commitment 5.868278e-7
GO:0019067 viral assembly, maturation, egress, and release 6.039635e-7
GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis 9.021501e-7
GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure 9.021501e-7
GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 9.021501e-7
GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 9.021501e-7
GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 9.021501e-7
GO:2000055 positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 9.021501e-7
GO:0061310 canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development 9.021501e-7
GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 9.021501e-7
GO:0006657 CDP-choline pathway 1.019237e-6
GO:0016579 protein deubiquitination 1.170502e-6
GO:0090245 axis elongation involved in somitogenesis 1.328838e-6
GO:0021874 Wnt receptor signaling pathway involved in forebrain neuroblast division 1.328838e-6
GO:0070536 protein K63-linked deubiquitination 1.336632e-6
GO:0002711 positive regulation of T cell mediated immunity 1.388583e-6
GO:0060850 regulation of transcription involved in cell fate commitment 1.640488e-6
GO:0044332 Wnt receptor signaling pathway involved in dorsal/ventral axis specification 1.887674e-6
GO:0044335 canonical Wnt receptor signaling pathway involved in neural crest cell differentiation 1.907162e-6
GO:0009785 blue light signaling pathway 1.950494e-6
GO:0000723 telomere maintenance 1.965626e-6
GO:0007126 meiosis 2.428475e-6
GO:0051320 S phase 2.429148e-6
GO:2000053 regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 2.520625e-6
GO:0070535 histone H2A K63-linked ubiquitination 2.950650e-6
GO:0014020 primary neural tube formation 3.323265e-6
GO:0010172 embryonic body morphogenesis 3.704317e-6
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 3.799450e-6
GO:0021570 rhombomere 4 development 4.260223e-6
GO:0008334 histone mRNA metabolic process 4.271910e-6
GO:0001843 neural tube closure 4.323005e-6
GO:0060836 lymphatic endothelial cell differentiation 4.356564e-6
GO:0006303 double-strand break repair via nonhomologous end joining 4.356564e-6
GO:0060606 tube closure 5.389138e-6
GO:0051289 protein homotetramerization 6.179725e-6
GO:0010719 negative regulation of epithelial to mesenchymal transition 6.417934e-6
GO:0072148 epithelial cell fate commitment 6.609773e-6
GO:0006529 asparagine biosynthetic process 7.199349e-6
GO:0006259 DNA metabolic process 8.010935e-6
GO:0032200 telomere organization 8.161613e-6
GO:0000236 mitotic prometaphase 8.863400e-6
GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway 1.055374e-5
GO:0002011 morphogenesis of an epithelial sheet 1.056384e-5
GO:0060691 epithelial cell maturation involved in salivary gland development 1.060984e-5
GO:0070086 ubiquitin-dependent endocytosis 1.060984e-5
GO:0060096 serotonin secretion, neurotransmission 1.060984e-5
GO:0060236 regulation of mitotic spindle organization 1.109651e-5
GO:0009637 response to blue light 1.109651e-5
GO:0045008 depyrimidination 1.124603e-5
GO:0000079 regulation of cyclin-dependent protein kinase activity 1.236372e-5
GO:0006310 DNA recombination 1.295822e-5
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 1.405397e-5
GO:0046544 development of secondary male sexual characteristics 1.507806e-5
GO:0071044 histone mRNA catabolic process 1.789540e-5
GO:2000351 regulation of endothelial cell apoptosis 1.792078e-5
GO:0070646 protein modification by small protein removal 2.055229e-5
GO:0043170 macromolecule metabolic process 2.392863e-5
GO:0006919 activation of caspase activity 2.475676e-5
GO:0070059 apoptosis in response to endoplasmic reticulum stress 2.486371e-5
GO:0014029 neural crest formation 2.685441e-5
GO:0071637 regulation of monocyte chemotactic protein-1 production 2.918222e-5
GO:0032663 regulation of interleukin-2 production 2.948315e-5
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 3.371801e-5
GO:0060980 cell migration involved in coronary vasculogenesis 3.418976e-5
GO:0046674 induction of retinal programmed cell death 3.719662e-5
GO:0048597 post-embryonic camera-type eye morphogenesis 3.719662e-5
GO:0032976 release of matrix enzymes from mitochondria 3.719662e-5
GO:0002352 B cell negative selection 3.719662e-5
GO:0001777 T cell homeostatic proliferation 3.719662e-5
GO:0006101 citrate metabolic process 3.818717e-5
GO:0002339 B cell selection 3.828224e-5
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 4.163530e-5
GO:0021612 facial nerve structural organization 4.313522e-5
GO:0051594 detection of glucose 4.549787e-5
GO:0003281 ventricular septum development 4.961920e-5
GO:0007091 mitotic metaphase/anaphase transition 5.463881e-5
GO:0021510 spinal cord development 5.469388e-5
GO:0071887 leukocyte apoptosis 5.787052e-5
GO:0090394 negative regulation of excitatory postsynaptic membrane potential 5.849247e-5
GO:0006281 DNA repair 6.037342e-5
GO:0009223 pyrimidine deoxyribonucleotide catabolic process 6.130124e-5
GO:0060379 cardiac muscle cell myoblast differentiation 6.467396e-5
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 6.486231e-5
GO:0042026 protein refolding 6.699838e-5
GO:0044237 cellular metabolic process 7.174048e-5
GO:0033127 regulation of histone phosphorylation 8.053025e-5
GO:0000279 M phase 8.129894e-5
GO:0003279 cardiac septum development 8.540265e-5
GO:0009886 post-embryonic morphogenesis 8.554066e-5
GO:0006235 dTTP biosynthetic process 8.626338e-5
GO:0002708 positive regulation of lymphocyte mediated immunity 9.032757e-5
GO:0072229 metanephric proximal convoluted tubule development 9.151941e-5
GO:0046670 positive regulation of retinal cell programmed cell death 9.151941e-5
GO:0046449 creatinine metabolic process 9.501579e-5
GO:0021915 neural tube development 9.596589e-5
GO:0007144 female meiosis I 1.006305e-4
GO:0035176 social behavior 1.133883e-4
GO:2000124 regulation of endocannabinoid signaling pathway 1.169045e-4
GO:0006102 isocitrate metabolic process 1.169045e-4
GO:0006552 leucine catabolic process 1.179597e-4
GO:0000726 non-recombinational repair 1.279028e-4
GO:0090129 positive regulation of synapse maturation 1.311508e-4
GO:0035065 regulation of histone acetylation 1.315921e-4
GO:0021794 thalamus development 1.420102e-4
GO:0070164 negative regulation of adiponectin secretion 1.516771e-4
GO:0035505 positive regulation of myosin light chain kinase activity 1.516771e-4
GO:0060355 positive regulation of cell adhesion molecule production 1.516771e-4
GO:0006244 pyrimidine nucleotide catabolic process 1.574140e-4
GO:0045086 positive regulation of interleukin-2 biosynthetic process 1.581556e-4
GO:0001783 B cell apoptosis 1.596819e-4
GO:0021546 rhombomere development 1.618971e-4
GO:0021569 rhombomere 3 development 1.732395e-4
GO:0019530 taurine metabolic process 1.732395e-4
GO:0010833 telomere maintenance via telomere lengthening 1.770635e-4
GO:0015936 coenzyme A metabolic process 1.774239e-4
GO:0009219 pyrimidine deoxyribonucleotide metabolic process 1.800137e-4
GO:0021512 spinal cord anterior/posterior patterning 1.801443e-4
GO:0021532 neural tube patterning 1.843378e-4
GO:0019368 fatty acid elongation, unsaturated fatty acid 1.903493e-4
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1.972272e-4
GO:0046676 negative regulation of insulin secretion 1.980364e-4
GO:0006479 protein methylation 1.993486e-4
GO:0032367 intracellular cholesterol transport 2.019417e-4
GO:0090128 regulation of synapse maturation 2.025250e-4
GO:0001522 pseudouridine synthesis 2.025250e-4
GO:0006285 base-excision repair, AP site formation 2.088220e-4
GO:0070163 regulation of adiponectin secretion 2.088258e-4
GO:0003218 cardiac left ventricle formation 2.122776e-4
GO:0034645 cellular macromolecule biosynthetic process 2.132323e-4
GO:0090291 negative regulation of osteoclast proliferation 2.137329e-4
GO:2000349 negative regulation of CD40 signaling pathway 2.137329e-4
GO:0072573 tolerance induction to lipopolysaccharide 2.137329e-4
GO:2000347 positive regulation of hepatocyte proliferation 2.137329e-4
GO:0034148 negative regulation of toll-like receptor 5 signaling pathway 2.137329e-4
GO:0070429 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 2.137329e-4
GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 2.137329e-4
GO:0045931 positive regulation of mitotic cell cycle 2.188438e-4
GO:2000352 negative regulation of endothelial cell apoptosis 2.213178e-4
GO:0000084 S phase of mitotic cell cycle 2.250859e-4
GO:0034333 adherens junction assembly 2.390815e-4
GO:0035441 cell migration involved in vasculogenesis 2.432381e-4
GO:0010107 potassium ion import 2.432381e-4
GO:0090399 replicative senescence 2.489588e-4
GO:0009956 radial pattern formation 2.501856e-4
GO:0060059 embryonic retina morphogenesis in camera-type eye 2.526854e-4
GO:0071542 dopaminergic neuron differentiation 2.526854e-4
GO:0043280 positive regulation of caspase activity 2.678394e-4
GO:0006790 sulfur compound metabolic process 2.691081e-4
GO:0061381 cell migration in diencephalon 2.761931e-4
GO:0061379 inferior colliculus development 2.761931e-4
GO:0061374 mammillothalamic axonal tract development 2.761931e-4
GO:0021855 hypothalamus cell migration 2.761931e-4
GO:0097105 presynaptic membrane assembly 2.831236e-4
GO:0006549 isoleucine metabolic process 2.980204e-4
GO:0030035 microspike assembly 2.989768e-4
GO:0042418 epinephrine biosynthetic process 3.102725e-4
GO:0006585 dopamine biosynthetic process from tyrosine 3.102725e-4
GO:0090278 negative regulation of peptide hormone secretion 3.165559e-4
GO:0070227 lymphocyte apoptosis 3.186630e-4
GO:0000255 allantoin metabolic process 3.245940e-4
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 3.283306e-4
GO:0007412 axon target recognition 3.283306e-4
GO:0048103 somatic stem cell division 3.359668e-4
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 3.488987e-4
GO:0046796 viral genome transport in host cell 3.578313e-4
GO:0003057 regulation of the force of heart contraction by chemical signal 3.604283e-4
GO:0031115 negative regulation of microtubule polymerization 3.787827e-4
GO:0050996 positive regulation of lipid catabolic process 3.837873e-4
GO:0046847 filopodium assembly 3.850941e-4
GO:0072195 kidney smooth muscle cell differentiation 3.866792e-4
GO:0072105 ureteric peristalsis 3.866792e-4
GO:0021997 neural plate axis specification 3.866792e-4
GO:0070858 negative regulation of bile acid biosynthetic process 3.866792e-4
GO:0003108 negative regulation of the force of heart contraction by chemical signal 4.041763e-4
GO:0051571 positive regulation of histone H3-K4 methylation 4.181299e-4
GO:0046888 negative regulation of hormone secretion 4.201739e-4
GO:0043648 dicarboxylic acid metabolic process 4.250079e-4
GO:0001660 fever generation 4.289340e-4
GO:0009081 branched chain family amino acid metabolic process 4.318587e-4
GO:0031397 negative regulation of protein ubiquitination 4.397268e-4
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA 4.470573e-4
GO:0021610 facial nerve morphogenesis 4.509074e-4
GO:0000414 regulation of histone H3-K36 methylation 4.509074e-4
GO:0046778 modification by virus of host mRNA processing 4.530338e-4
GO:0032365 intracellular lipid transport 4.609957e-4
GO:0032729 positive regulation of interferon-gamma production 4.705191e-4
GO:0042149 cellular response to glucose starvation 4.744299e-4
GO:0090224 regulation of spindle organization 4.880180e-4
GO:0030917 midbrain-hindbrain boundary development 4.986596e-4
GO:0051262 protein tetramerization 5.116124e-4
GO:2000348 regulation of CD40 signaling pathway 5.239217e-4
GO:0035066 positive regulation of histone acetylation 5.547686e-4
GO:0034140 negative regulation of toll-like receptor 3 signaling pathway 5.776824e-4
GO:0060558 regulation of calcidiol 1-monooxygenase activity 5.989868e-4
GO:0009059 macromolecule biosynthetic process 6.016674e-4
GO:0000724 double-strand break repair via homologous recombination 6.084048e-4
GO:0060690 epithelial cell differentiation involved in salivary gland development 6.110386e-4
GO:0071625 vocalization behavior 6.118367e-4
GO:0048541 Peyer's patch development 6.265740e-4
GO:0022403 cell cycle phase 6.359266e-4
GO:0061324 canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation 6.381677e-4
GO:0043653 mitochondrial fragmentation involved in apoptosis 6.381677e-4
GO:0001985 negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 6.459587e-4
GO:0021873 forebrain neuroblast division 6.507084e-4
GO:0007127 meiosis I 6.541949e-4
GO:0035247 peptidyl-arginine omega-N-methylation 6.619996e-4
GO:0021561 facial nerve development 6.619996e-4
GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 6.669561e-4
GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 6.669561e-4
GO:0030497 fatty acid elongation 6.962946e-4
GO:0051043 regulation of membrane protein ectodomain proteolysis 6.977451e-4
GO:0000725 recombinational repair 6.977451e-4
GO:0031427 response to methotrexate 7.039697e-4
GO:0045769 negative regulation of asymmetric cell division 7.213511e-4
GO:0042414 epinephrine metabolic process 7.213511e-4
GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 7.326670e-4
GO:0006695 cholesterol biosynthetic process 7.358973e-4
GO:0043137 DNA replication, removal of RNA primer 7.375561e-4
GO:0003360 brainstem development 7.375561e-4
GO:0034116 positive regulation of heterotypic cell-cell adhesion 7.606239e-4
GO:0002238 response to molecule of fungal origin 7.660309e-4
GO:0021943 formation of radial glial scaffolds 7.660309e-4
GO:0042770 signal transduction in response to DNA damage 7.829201e-4
GO:2000050 regulation of non-canonical Wnt receptor signaling pathway 7.900252e-4
GO:0021604 cranial nerve structural organization 7.974857e-4
GO:0006338 chromatin remodeling 8.122104e-4
GO:0000375 RNA splicing, via transesterification reactions 8.304895e-4
GO:0042113 B cell activation 8.423462e-4
GO:0071108 protein K48-linked deubiquitination 8.473323e-4
GO:0006551 leucine metabolic process 8.737008e-4
GO:0060968 regulation of gene silencing 8.836344e-4
GO:0045292 nuclear mRNA cis splicing, via spliceosome 9.496419e-4
GO:0008156 negative regulation of DNA replication 9.598066e-4
GO:0060292 long term synaptic depression 9.630883e-4
GO:0033601 positive regulation of mammary gland epithelial cell proliferation 9.914392e-4
GO:0071157 negative regulation of cell cycle arrest 1.008310e-3
GO:0006284 base-excision repair 1.010852e-3
GO:0090149 membrane fission involved in mitochondrial fission 1.014276e-3
GO:0003374 dynamin polymerization involved in mitochondrial fission 1.014276e-3
GO:0009088 threonine biosynthetic process 1.014276e-3
GO:0045830 positive regulation of isotype switching 1.042146e-3
GO:0034063 stress granule assembly 1.052140e-3
GO:0051131 chaperone-mediated protein complex assembly 1.072846e-3
GO:0002792 negative regulation of peptide secretion 1.075879e-3
GO:0015966 diadenosine tetraphosphate biosynthetic process 1.076692e-3
GO:0045076 regulation of interleukin-2 biosynthetic process 1.082959e-3
GO:0051402 neuron apoptosis 1.092309e-3
GO:0034135 regulation of toll-like receptor 2 signaling pathway 1.099166e-3
GO:0060173 limb development 1.119584e-3
GO:0070544 histone H3-K36 demethylation 1.125026e-3
GO:0002706 regulation of lymphocyte mediated immunity 1.125230e-3
GO:0001841 neural tube formation 1.146483e-3
GO:0006573 valine metabolic process 1.159068e-3
GO:0048537 mucosal-associated lymphoid tissue development 1.176037e-3
GO:0007213 muscarinic acetylcholine receptor signaling pathway 1.176127e-3
GO:0006366 transcription from RNA polymerase II promoter 1.194226e-3
GO:0034080 CenH3-containing nucleosome assembly at centromere 1.212836e-3
GO:0048469 cell maturation 1.215924e-3
GO:0071397 cellular response to cholesterol 1.222396e-3
GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation 1.244325e-3
GO:0010564 regulation of cell cycle process 1.265238e-3
GO:0016571 histone methylation 1.270277e-3
GO:0032770 positive regulation of monooxygenase activity 1.284490e-3
GO:0006982 response to lipid hydroperoxide 1.320907e-3
GO:0002158 osteoclast proliferation 1.334863e-3
GO:0046487 glyoxylate metabolic process 1.353317e-3
GO:0042214 terpene metabolic process 1.372695e-3
GO:0014813 satellite cell commitment 1.372695e-3
GO:0000038 very long-chain fatty acid metabolic process 1.380123e-3
GO:0044340 canonical Wnt receptor signaling pathway involved in regulation of cell proliferation 1.408570e-3
GO:0035137 hindlimb morphogenesis 1.453755e-3
GO:0001922 B-1 B cell homeostasis 1.479564e-3
GO:0032464 positive regulation of protein homooligomerization 1.483801e-3
GO:0014805 smooth muscle adaptation 1.541836e-3
GO:0008152 metabolic process 1.556862e-3
GO:0006974 response to DNA damage stimulus 1.609464e-3
GO:0071156 regulation of cell cycle arrest 1.616090e-3
GO:0051276 chromosome organization 1.625501e-3
GO:2000345 regulation of hepatocyte proliferation 1.672863e-3
GO:0002709 regulation of T cell mediated immunity 1.677112e-3
GO:0070857 regulation of bile acid biosynthetic process 1.677938e-3
GO:0090244 Wnt receptor signaling pathway involved in somitogenesis 1.681113e-3
GO:0035261 external genitalia morphogenesis 1.681113e-3
GO:0033129 positive regulation of histone phosphorylation 1.695500e-3
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis 1.720286e-3
GO:0050796 regulation of insulin secretion 1.757013e-3
GO:0009067 aspartate family amino acid biosynthetic process 1.765179e-3
GO:0035425 autocrine signaling 1.770409e-3
GO:0032229 negative regulation of synaptic transmission, GABAergic 1.771308e-3
GO:0097090 presynaptic membrane organization 1.772473e-3
GO:0006283 transcription-coupled nucleotide-excision repair 1.787441e-3
GO:0043254 regulation of protein complex assembly 1.794362e-3
GO:0052314 phytoalexin metabolic process 1.801505e-3
GO:0033342 negative regulation of collagen binding 1.801505e-3
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 1.801505e-3
GO:0060977 coronary vasculature morphogenesis 1.831521e-3
GO:0048285 organelle fission 1.837130e-3
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 1.849856e-3
GO:0046619 optic placode formation involved in camera-type eye formation 1.871817e-3
GO:0051252 regulation of RNA metabolic process 1.939023e-3
GO:0002639 positive regulation of immunoglobulin production 1.995820e-3
GO:0060019 radial glial cell differentiation 2.004979e-3
GO:0007131 reciprocal meiotic recombination 2.006087e-3
GO:2000756 regulation of peptidyl-lysine acetylation 2.011452e-3
GO:0006825 copper ion transport 2.015462e-3
GO:0051726 regulation of cell cycle 2.048330e-3
GO:0046358 butyrate biosynthetic process 2.057489e-3
GO:2000114 regulation of establishment of cell polarity 2.075103e-3
GO:0021903 rostrocaudal neural tube patterning 2.079056e-3
GO:0002331 pre-B cell allelic exclusion 2.081577e-3
GO:0007128 meiotic prophase I 2.102669e-3
GO:0046850 regulation of bone remodeling 2.110735e-3
GO:0043414 macromolecule methylation 2.144860e-3
GO:0040032 post-embryonic body morphogenesis 2.162660e-3
GO:0000239 pachytene 2.162660e-3
GO:0006749 glutathione metabolic process 2.207896e-3
GO:0045911 positive regulation of DNA recombination 2.233971e-3
GO:0021932 hindbrain radial glia guided cell migration 2.284393e-3
GO:0007032 endosome organization 2.302181e-3
GO:0046690 response to tellurium ion 2.305204e-3
GO:0035444 nickel ion transmembrane transport 2.305204e-3
GO:0070627 ferrous iron import 2.305204e-3
GO:0071352 cellular response to interleukin-2 2.305204e-3
GO:0015676 vanadium ion transport 2.305204e-3
GO:0015692 lead ion transport 2.305204e-3
GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation 2.305204e-3
GO:0009645 response to low light intensity stimulus 2.305204e-3
GO:0034755 iron ion transmembrane transport 2.307965e-3
GO:0015959 diadenosine polyphosphate metabolic process 2.307965e-3
GO:0031104 dendrite regeneration 2.375159e-3
GO:0060039 pericardium development 2.391845e-3
GO:0006308 DNA catabolic process 2.394482e-3
GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity 2.551732e-3
GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway 2.551732e-3
GO:0019915 lipid storage 2.553677e-3
GO:0051301 cell division 2.555643e-3
GO:0030730 sequestering of triglyceride 2.585824e-3
GO:0080164 regulation of nitric oxide metabolic process 2.607351e-3
GO:0043381 negative regulation of memory T cell differentiation 2.607351e-3
GO:0030201 heparan sulfate proteoglycan metabolic process 2.645879e-3
GO:0050691 regulation of defense response to virus by host 2.645879e-3
GO:0021987 cerebral cortex development 2.663549e-3
GO:0032819 positive regulation of natural killer cell proliferation 2.705581e-3
GO:0001983 baroreceptor response to increased systemic arterial blood pressure 2.705581e-3
GO:0044339 canonical Wnt receptor signaling pathway involved in osteoblast differentiation 2.724987e-3
GO:0044338 canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation 2.724987e-3
GO:2001054 negative regulation of mesenchymal cell apoptosis 2.724987e-3
GO:0010587 miRNA catabolic process 2.724987e-3
GO:0009202 deoxyribonucleoside triphosphate biosynthetic process 2.724987e-3
GO:0021986 habenula development 2.741460e-3
GO:0033599 regulation of mammary gland epithelial cell proliferation 2.751158e-3
GO:0006105 succinate metabolic process 2.802557e-3
GO:0009450 gamma-aminobutyric acid catabolic process 2.813629e-3
GO:0032768 regulation of monooxygenase activity 2.837828e-3
GO:0032825 positive regulation of natural killer cell differentiation 2.858669e-3
GO:0006355 regulation of transcription, DNA-dependent 2.886463e-3
GO:0009822 alkaloid catabolic process 2.887906e-3
GO:0045799 positive regulation of chromatin assembly or disassembly 2.887906e-3
GO:0051661 maintenance of centrosome location 2.887906e-3
GO:0045472 response to ether 2.887906e-3
GO:0019218 regulation of steroid metabolic process 2.925136e-3
GO:0051891 positive regulation of cardioblast differentiation 2.942157e-3
GO:0090273 regulation of somatostatin secretion 3.018421e-3
GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure 3.018421e-3
GO:0051204 protein insertion into mitochondrial membrane 3.052736e-3
GO:0031055 chromatin remodeling at centromere 3.056016e-3
GO:0022038 corpus callosum development 3.086390e-3
GO:0072194 kidney smooth muscle tissue development 3.094410e-3
GO:0050893 sensory processing 3.094410e-3
GO:0006426 glycyl-tRNA aminoacylation 3.108515e-3
GO:0006273 lagging strand elongation 3.108515e-3
GO:0010459 negative regulation of heart rate 3.122486e-3
GO:0045588 positive regulation of gamma-delta T cell differentiation 3.185030e-3
GO:0033865 nucleoside bisphosphate metabolic process 3.188243e-3
GO:0034103 regulation of tissue remodeling 3.190674e-3
GO:0032201 telomere maintenance via semi-conservative replication 3.199164e-3
GO:0032000 positive regulation of fatty acid beta-oxidation 3.264618e-3
GO:0051205 protein insertion into membrane 3.357219e-3
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 3.372019e-3
GO:0034626 fatty acid elongation, polyunsaturated fatty acid 3.394826e-3
GO:0060689 cell differentiation involved in salivary gland development 3.394826e-3
GO:0045410 positive regulation of interleukin-6 biosynthetic process 3.408850e-3
GO:0072560 type B pancreatic cell maturation 3.429051e-3
GO:0070295 renal water absorption 3.429051e-3
GO:0030910 olfactory placode formation 3.429051e-3
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 3.488059e-3
GO:0014048 regulation of glutamate secretion 3.510248e-3
GO:2000116 regulation of cysteine-type endopeptidase activity 3.517889e-3
GO:0001838 embryonic epithelial tube formation 3.520434e-3
GO:0060061 Spemann organizer formation 3.527260e-3
GO:0033076 isoquinoline alkaloid metabolic process 3.553358e-3
GO:0006325 chromatin organization 3.684319e-3
GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 3.684455e-3
GO:0015891 siderophore transport 3.715629e-3
GO:0042339 keratan sulfate metabolic process 3.715629e-3
GO:0006463 steroid hormone receptor complex assembly 3.715629e-3
GO:0035246 peptidyl-arginine N-methylation 3.727964e-3
GO:0032817 regulation of natural killer cell proliferation 3.727964e-3
GO:0045822 negative regulation of heart contraction 3.841926e-3
GO:0006927 transformed cell apoptosis 3.890100e-3
GO:0055024 regulation of cardiac muscle tissue development 3.890634e-3
GO:0045647 negative regulation of erythrocyte differentiation 3.923976e-3
GO:0060973 cell migration involved in heart development 3.953696e-3
GO:0006600 creatine metabolic process 4.175992e-3
GO:0048593 camera-type eye morphogenesis 4.228508e-3
GO:0008535 respiratory chain complex IV assembly 4.237216e-3
GO:0031424 keratinization 4.282531e-3
GO:2000270 negative regulation of fibroblast apoptosis 4.304962e-3
GO:2000271 positive regulation of fibroblast apoptosis 4.304962e-3
GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 4.304962e-3
GO:0071773 cellular response to BMP stimulus 4.304962e-3
GO:0044345 stromal-epithelial cell signaling involved in prostate gland development 4.304962e-3
GO:0017145 stem cell division 4.335620e-3
GO:2000677 regulation of transcription regulatory region DNA binding 4.364463e-3
GO:0043044 ATP-dependent chromatin remodeling 4.364463e-3
GO:0051790 short-chain fatty acid biosynthetic process 4.476285e-3
GO:0070105 positive regulation of interleukin-6-mediated signaling pathway 4.476285e-3
GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 4.476285e-3
GO:0032066 nucleolus to nucleoplasm transport 4.476285e-3
GO:0010248 establishment or maintenance of transmembrane electrochemical gradient 4.476285e-3
GO:0006533 aspartate catabolic process 4.476285e-3
GO:0000018 regulation of DNA recombination 4.497689e-3
GO:0060535 trachea cartilage morphogenesis 4.535459e-3
GO:0018216 peptidyl-arginine methylation 4.559945e-3
GO:0046851 negative regulation of bone remodeling 4.633782e-3
GO:0031396 regulation of protein ubiquitination 4.649189e-3
GO:0043486 histone exchange 4.756443e-3
GO:0051324 prophase 4.761681e-3
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 4.788598e-3
GO:0006528 asparagine metabolic process 4.807838e-3
GO:0006334 nucleosome assembly 4.827721e-3
GO:0070672 response to interleukin-15 4.848868e-3
GO:0032057 negative regulation of translational initiation in response to stress 5.009422e-3
GO:0046645 positive regulation of gamma-delta T cell activation 5.025930e-3
GO:0008299 isoprenoid biosynthetic process 5.068569e-3
GO:0035148 tube formation 5.119134e-3
GO:0072175 epithelial tube formation 5.126164e-3
GO:2000079 regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 5.145786e-3
GO:0051097 negative regulation of helicase activity 5.145786e-3
GO:0034139 regulation of toll-like receptor 3 signaling pathway 5.167818e-3
GO:0046185 aldehyde catabolic process 5.217644e-3
GO:0032259 methylation 5.239051e-3
GO:2000112 regulation of cellular macromolecule biosynthetic process 5.246462e-3
GO:0060976 coronary vasculature development 5.289211e-3
GO:0035634 response to stilbenoid 5.289211e-3
GO:0000266 mitochondrial fission 5.289211e-3
GO:0022616 DNA strand elongation 5.298073e-3
GO:0021700 developmental maturation 5.300888e-3
GO:0001782 B cell homeostasis 5.391958e-3
GO:0006607 NLS-bearing substrate import into nucleus 5.410055e-3
GO:0042416 dopamine biosynthetic process 5.422615e-3
GO:0034392 negative regulation of smooth muscle cell apoptosis 5.458560e-3
GO:0009068 aspartate family amino acid catabolic process 5.485203e-3
GO:0051569 regulation of histone H3-K4 methylation 5.485203e-3
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 5.554638e-3
GO:0001743 optic placode formation 5.651540e-3
GO:0014050 negative regulation of glutamate secretion 5.694294e-3
GO:0050891 multicellular organismal water homeostasis 5.703402e-3
GO:0001659 temperature homeostasis 5.743359e-3
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.754486e-3
GO:0006646 phosphatidylethanolamine biosynthetic process 5.760175e-3
GO:0032876 negative regulation of DNA endoreduplication 5.760175e-3
GO:0010952 positive regulation of peptidase activity 5.852090e-3
GO:0061316 canonical Wnt receptor signaling pathway involved in heart development 5.884541e-3
GO:0051353 positive regulation of oxidoreductase activity 5.938254e-3
GO:0000398 nuclear mRNA splicing, via spliceosome 5.975443e-3
GO:0090276 regulation of peptide hormone secretion 6.027211e-3
GO:0016140 O-glycoside metabolic process 6.078583e-3
GO:0035024 negative regulation of Rho protein signal transduction 6.109727e-3
GO:0000019 regulation of mitotic recombination 6.110247e-3
GO:0071168 protein localization to chromatin 6.110247e-3
GO:0010948 negative regulation of cell cycle process 6.147205e-3
GO:0051930 regulation of sensory perception of pain 6.194275e-3
GO:0001779 natural killer cell differentiation 6.292686e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0090304 nucleic acid metabolic process 1.994331e-16
GO:0016070 RNA metabolic process 2.861030e-12
GO:0006139 nucleobase-containing compound metabolic process 7.413870e-12
GO:0044260 cellular macromolecule metabolic process 1.533992e-11
GO:0042733 embryonic digit morphogenesis 1.627549e-11
GO:0010467 gene expression 1.023694e-10
GO:0034641 cellular nitrogen compound metabolic process 3.504483e-10
GO:0006807 nitrogen compound metabolic process 8.893119e-10
GO:0003309 type B pancreatic cell differentiation 9.441651e-10
GO:0060429 epithelium development 9.780988e-10
GO:0001736 establishment of planar polarity 1.119363e-9
GO:0045736 negative regulation of cyclin-dependent protein kinase activity 1.316519e-9
GO:0001945 lymph vessel development 1.536995e-9
GO:0007164 establishment of tissue polarity 2.716312e-9
GO:0051684 maintenance of Golgi location 3.641314e-9
GO:0046709 IDP catabolic process 4.431151e-9
GO:0046032 ADP catabolic process 4.431151e-9
GO:0051726 regulation of cell cycle 5.683420e-9
GO:0003279 cardiac septum development 6.238593e-9
GO:0043170 macromolecule metabolic process 6.338225e-9
GO:0060411 cardiac septum morphogenesis 1.093255e-8
GO:0051645 Golgi localization 2.699758e-8
GO:0045786 negative regulation of cell cycle 4.790769e-8
GO:0030855 epithelial cell differentiation 7.301743e-8
GO:0006974 response to DNA damage stimulus 8.774461e-8
GO:0009956 radial pattern formation 9.461499e-8
GO:0032774 RNA biosynthetic process 9.925289e-8
GO:0015074 DNA integration 1.054522e-7
GO:0001738 morphogenesis of a polarized epithelium 1.369369e-7
GO:0035282 segmentation 1.371055e-7
GO:0032912 negative regulation of transforming growth factor beta2 production 1.551173e-7
GO:0031577 spindle checkpoint 1.640761e-7
GO:0051301 cell division 2.636669e-7
GO:0006351 transcription, DNA-dependent 2.686968e-7
GO:0007067 mitosis 2.914650e-7
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 2.969826e-7
GO:0007389 pattern specification process 3.556897e-7
GO:0009952 anterior/posterior pattern specification 3.599216e-7
GO:0031503 protein complex localization 3.777013e-7
GO:0060839 endothelial cell fate commitment 3.937405e-7
GO:0051661 maintenance of centrosome location 4.282727e-7
GO:0060836 lymphatic endothelial cell differentiation 4.518201e-7
GO:0000087 M phase of mitotic cell cycle 4.696605e-7
GO:0090179 planar cell polarity pathway involved in neural tube closure 5.910800e-7
GO:0045165 cell fate commitment 5.955319e-7
GO:0071156 regulation of cell cycle arrest 6.266562e-7
GO:0045137 development of primary sexual characteristics 6.673101e-7
GO:0046452 dihydrofolate metabolic process 8.732728e-7
GO:0072240 metanephric DCT cell differentiation 9.468874e-7
GO:0072227 metanephric macula densa development 9.468874e-7
GO:0043066 negative regulation of apoptosis 1.147592e-6
GO:0031427 response to methotrexate 1.240022e-6
GO:0043069 negative regulation of programmed cell death 1.305778e-6
GO:0048286 lung alveolus development 1.375355e-6
GO:0006281 DNA repair 1.416157e-6
GO:0009181 purine ribonucleoside diphosphate catabolic process 1.482575e-6
GO:0060412 ventricular septum morphogenesis 1.603707e-6
GO:0006420 arginyl-tRNA aminoacylation 1.609321e-6
GO:0061180 mammary gland epithelium development 1.774581e-6
GO:0034645 cellular macromolecule biosynthetic process 2.017681e-6
GO:0007493 endodermal cell fate determination 2.035677e-6
GO:0007548 sex differentiation 2.047806e-6
GO:0048285 organelle fission 2.231136e-6
GO:0003002 regionalization 2.279784e-6
GO:0046661 male sex differentiation 2.523897e-6
GO:0009059 macromolecule biosynthetic process 2.679225e-6
GO:0034063 stress granule assembly 2.853042e-6
GO:0003281 ventricular septum development 3.020813e-6
GO:0045995 regulation of embryonic development 3.063880e-6
GO:0072233 metanephric thick ascending limb development 3.280594e-6
GO:0072218 metanephric ascending thin limb development 3.280594e-6
GO:0060548 negative regulation of cell death 3.404785e-6
GO:0042475 odontogenesis of dentine-containing tooth 3.604803e-6
GO:0071542 dopaminergic neuron differentiation 3.652544e-6
GO:0003151 outflow tract morphogenesis 4.207354e-6
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 4.394822e-6
GO:0008406 gonad development 4.474877e-6
GO:0071173 spindle assembly checkpoint 5.590752e-6
GO:0000279 M phase 5.658895e-6
GO:0072202 cell differentiation involved in metanephros development 5.855346e-6
GO:0032908 regulation of transforming growth factor beta1 production 5.855346e-6
GO:0009236 cobalamin biosynthetic process 5.914190e-6
GO:0032911 negative regulation of transforming growth factor beta1 production 6.387055e-6
GO:0072148 epithelial cell fate commitment 6.465315e-6
GO:0060173 limb development 6.780211e-6
GO:0046031 ADP metabolic process 7.278483e-6
GO:0060644 mammary gland epithelial cell differentiation 7.289085e-6
GO:0021889 olfactory bulb interneuron differentiation 8.162105e-6
GO:0030801 positive regulation of cyclic nucleotide metabolic process 8.846900e-6
GO:0034622 cellular macromolecular complex assembly 9.095485e-6
GO:0034421 post-translational protein acetylation 9.207778e-6
GO:0007566 embryo implantation 9.484220e-6
GO:0035050 embryonic heart tube development 9.630088e-6
GO:0035567 non-canonical Wnt receptor signaling pathway 1.020374e-5
GO:0007420 brain development 1.152230e-5
GO:0030326 embryonic limb morphogenesis 1.161836e-5
GO:0035967 cellular response to topologically incorrect protein 1.195433e-5
GO:0021869 forebrain ventricular zone progenitor cell division 1.368730e-5
GO:0016073 snRNA metabolic process 1.382551e-5
GO:0050678 regulation of epithelial cell proliferation 1.532934e-5
GO:0071158 positive regulation of cell cycle arrest 1.615548e-5
GO:0000578 embryonic axis specification 1.627559e-5
GO:0006259 DNA metabolic process 1.634823e-5
GO:0022403 cell cycle phase 1.654395e-5
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 1.704086e-5
GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis 1.864742e-5
GO:0061381 cell migration in diencephalon 2.059990e-5
GO:0061379 inferior colliculus development 2.059990e-5
GO:0010045 response to nickel ion 2.059990e-5
GO:0021855 hypothalamus cell migration 2.059990e-5
GO:0061374 mammillothalamic axonal tract development 2.059990e-5
GO:0006355 regulation of transcription, DNA-dependent 2.132386e-5
GO:0008625 induction of apoptosis via death domain receptors 2.379919e-5
GO:0051085 chaperone mediated protein folding requiring cofactor 2.478191e-5
GO:0051382 kinetochore assembly 2.495486e-5
GO:0045345 positive regulation of MHC class I biosynthetic process 2.495486e-5
GO:0022402 cell cycle process 2.540236e-5
GO:0050680 negative regulation of epithelial cell proliferation 2.543774e-5
GO:0060575 intestinal epithelial cell differentiation 2.635289e-5
GO:0002009 morphogenesis of an epithelium 2.686537e-5
GO:0003310 pancreatic A cell differentiation 2.979496e-5
GO:0009889 regulation of biosynthetic process 3.039701e-5
GO:0051252 regulation of RNA metabolic process 3.058783e-5
GO:0070389 chaperone cofactor-dependent protein refolding 3.101941e-5
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway 3.180781e-5
GO:0022011 myelination in peripheral nervous system 3.180781e-5
GO:0034621 cellular macromolecular complex subunit organization 3.244006e-5
GO:0046092 deoxycytidine metabolic process 3.329255e-5
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 3.377188e-5
GO:2000065 negative regulation of cortisol biosynthetic process 3.377188e-5
GO:0072259 metanephric interstitial cell development 3.377188e-5
GO:0072208 metanephric smooth muscle tissue development 3.377188e-5
GO:0032348 negative regulation of aldosterone biosynthetic process 3.377188e-5
GO:0072169 specification of posterior mesonephric tubule identity 3.377188e-5
GO:0072168 specification of anterior mesonephric tubule identity 3.377188e-5
GO:0072184 renal vesicle progenitor cell differentiation 3.377188e-5
GO:0045541 negative regulation of cholesterol biosynthetic process 3.535994e-5
GO:0060931 sinoatrial node cell development 4.059727e-5
GO:0003167 atrioventricular bundle cell differentiation 4.059727e-5
GO:0042476 odontogenesis 4.168463e-5
GO:0009191 ribonucleoside diphosphate catabolic process 4.428682e-5
GO:0060795 cell fate commitment involved in formation of primary germ layers 4.451088e-5
GO:0007049 cell cycle 4.479864e-5
GO:0071712 ER-associated misfolded protein catabolic process 5.630273e-5
GO:0030970 retrograde protein transport, ER to cytosol 5.630273e-5
GO:0048608 reproductive structure development 5.649002e-5
GO:0019219 regulation of nucleobase-containing compound metabolic process 5.857137e-5
GO:0071635 negative regulation of transforming growth factor beta production 5.915221e-5
GO:0090399 replicative senescence 6.495716e-5
GO:0009134 nucleoside diphosphate catabolic process 6.495716e-5
GO:0007094 mitotic cell cycle spindle assembly checkpoint 7.053621e-5
GO:0051383 kinetochore organization 7.162774e-5
GO:0045446 endothelial cell differentiation 7.167759e-5
GO:0001756 somitogenesis 7.273054e-5
GO:2000112 regulation of cellular macromolecule biosynthetic process 7.591432e-5
GO:0060638 mesenchymal-epithelial cell signaling 7.598545e-5
GO:0010556 regulation of macromolecule biosynthetic process 7.816859e-5
GO:0071174 mitotic cell cycle spindle checkpoint 8.031172e-5
GO:0007569 cell aging 8.095122e-5
GO:0035136 forelimb morphogenesis 8.359744e-5
GO:2000617 positive regulation of histone H3-K9 acetylation 8.391304e-5
GO:2000620 positive regulation of histone H4-K16 acetylation 8.391304e-5
GO:0070512 positive regulation of histone H4-K20 methylation 8.391304e-5
GO:0061350 planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 8.569089e-5
GO:0061354 planar cell polarity pathway involved in pericardium morphogenesis 8.569089e-5
GO:0061349 planar cell polarity pathway involved in cardiac right atrium morphogenesis 8.569089e-5
GO:0070314 G1 to G0 transition 8.569089e-5
GO:0060210 metestrus 8.569089e-5
GO:0061348 planar cell polarity pathway involved in ventricular septum morphogenesis 8.569089e-5
GO:0006651 diacylglycerol biosynthetic process 8.569089e-5
GO:0061347 planar cell polarity pathway involved in outflow tract morphogenesis 8.569089e-5
GO:0000278 mitotic cell cycle 8.826370e-5
GO:0035115 embryonic forelimb morphogenesis 8.961571e-5
GO:0048343 paraxial mesodermal cell fate commitment 8.997431e-5
GO:0061077 chaperone-mediated protein folding 9.115944e-5
GO:0060921 sinoatrial node cell differentiation 9.116364e-5
GO:2001022 positive regulation of response to DNA damage stimulus 9.267129e-5
GO:0042473 outer ear morphogenesis 9.320439e-5
GO:2000543 positive regulation of gastrulation 9.549174e-5
GO:0014044 Schwann cell development 9.598481e-5
GO:0002065 columnar/cuboidal epithelial cell differentiation 1.004685e-4
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin 1.005007e-4
GO:0009179 purine ribonucleoside diphosphate metabolic process 1.016843e-4
GO:0044249 cellular biosynthetic process 1.030187e-4
GO:0060982 coronary artery morphogenesis 1.031797e-4
GO:0021904 dorsal/ventral neural tube patterning 1.120958e-4
GO:0060932 His-Purkinje system cell differentiation 1.164520e-4
GO:0060926 pacemaker cell development 1.164520e-4
GO:0014034 neural crest cell fate commitment 1.172735e-4
GO:0044237 cellular metabolic process 1.186037e-4
GO:0061053 somite development 1.262741e-4
GO:0001895 retina homeostasis 1.310775e-4
GO:0065004 protein-DNA complex assembly 1.315502e-4
GO:0007422 peripheral nervous system development 1.331682e-4
GO:0002070 epithelial cell maturation 1.338004e-4
GO:0060067 cervix development 1.361918e-4
GO:0022618 ribonucleoprotein complex assembly 1.370970e-4
GO:0006975 DNA damage induced protein phosphorylation 1.372972e-4
GO:0021891 olfactory bulb interneuron development 1.403313e-4
GO:0003158 endothelium development 1.406217e-4
GO:0010463 mesenchymal cell proliferation 1.427157e-4
GO:0051171 regulation of nitrogen compound metabolic process 1.430734e-4
GO:0046884 follicle-stimulating hormone secretion 1.471575e-4
GO:0032275 luteinizing hormone secretion 1.471575e-4
GO:0008595 anterior/posterior axis specification, embryo 1.480112e-4
GO:0006261 DNA-dependent DNA replication 1.504375e-4
GO:0045343 regulation of MHC class I biosynthetic process 1.671128e-4
GO:0006396 RNA processing 1.715039e-4
GO:0031326 regulation of cellular biosynthetic process 1.724740e-4
GO:0072234 metanephric nephron tubule development 1.732580e-4
GO:0014037 Schwann cell differentiation 1.732580e-4
GO:0006457 protein folding 1.764629e-4
GO:0002741 positive regulation of cytokine secretion involved in immune response 1.812417e-4
GO:0072170 metanephric tubule development 1.824564e-4
GO:0090103 cochlea morphogenesis 1.835420e-4
GO:0007417 central nervous system development 1.934505e-4
GO:0001711 endodermal cell fate commitment 1.952478e-4
GO:0009058 biosynthetic process 1.981947e-4
GO:0000079 regulation of cyclin-dependent protein kinase activity 1.991227e-4
GO:0046952 ketone body catabolic process 2.021861e-4
GO:0003163 sinoatrial node development 2.052088e-4
GO:0072221 metanephric distal convoluted tubule development 2.052088e-4
GO:0045986 negative regulation of smooth muscle contraction 2.107107e-4
GO:0072207 metanephric epithelium development 2.126078e-4
GO:0003205 cardiac chamber development 2.174542e-4
GO:0060920 pacemaker cell differentiation 2.282150e-4
GO:0060743 epithelial cell maturation involved in prostate gland development 2.372984e-4
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 2.372984e-4
GO:0090009 primitive streak formation 2.408095e-4
GO:0051084 'de novo' posttranslational protein folding 2.408095e-4
GO:0060479 lung cell differentiation 2.411975e-4
GO:0010468 regulation of gene expression 2.495753e-4
GO:0001975 response to amphetamine 2.501048e-4
GO:0071826 ribonucleoprotein complex subunit organization 2.502823e-4
GO:0016071 mRNA metabolic process 2.526023e-4
GO:0045668 negative regulation of osteoblast differentiation 2.536302e-4
GO:0072017 distal tubule development 2.571593e-4
GO:0031576 G2/M transition checkpoint 2.597260e-4
GO:0060117 auditory receptor cell development 2.633010e-4
GO:0010470 regulation of gastrulation 2.648459e-4
GO:0042351 'de novo' GDP-L-fucose biosynthetic process 2.651930e-4
GO:0030799 regulation of cyclic nucleotide metabolic process 2.654800e-4
GO:0002011 morphogenesis of an epithelial sheet 2.661756e-4
GO:0051095 regulation of helicase activity 2.700103e-4
GO:0032287 peripheral nervous system myelin maintenance 2.700103e-4
GO:0017148 negative regulation of translation 2.784915e-4
GO:0003323 type B pancreatic cell development 2.804546e-4
GO:0042770 signal transduction in response to DNA damage 2.824523e-4
GO:2000798 negative regulation of amniotic stem cell differentiation 2.847505e-4
GO:2000706 negative regulation of dense core granule biogenesis 2.847505e-4
GO:0019047 provirus integration 2.847505e-4
GO:0046591 embryonic leg joint morphogenesis 2.866637e-4
GO:0030510 regulation of BMP signaling pathway 2.949183e-4
GO:0035987 endodermal cell differentiation 2.974067e-4
GO:0048850 hypophysis morphogenesis 3.061595e-4
GO:0033108 mitochondrial respiratory chain complex assembly 3.063845e-4
GO:0072236 metanephric loop of Henle development 3.099530e-4
GO:0044238 primary metabolic process 3.122245e-4
GO:0072091 regulation of stem cell proliferation 3.132766e-4
GO:0048339 paraxial mesoderm development 3.146563e-4
GO:0009890 negative regulation of biosynthetic process 3.190028e-4
GO:0061338 atrioventricular node impulse conduction delay 3.290589e-4
GO:0010558 negative regulation of macromolecule biosynthetic process 3.299038e-4
GO:0046546 development of primary male sexual characteristics 3.373015e-4
GO:0030879 mammary gland development 3.380856e-4
GO:0060285 ciliary cell motility 3.381922e-4
GO:0072194 kidney smooth muscle tissue development 3.381922e-4
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 3.381922e-4
GO:0060286 flagellar cell motility 3.411495e-4
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 3.411495e-4
GO:0042026 protein refolding 3.425099e-4
GO:0035108 limb morphogenesis 3.428238e-4
GO:0006463 steroid hormone receptor complex assembly 3.459938e-4
GO:0000075 cell cycle checkpoint 3.461672e-4
GO:0035117 embryonic arm morphogenesis 3.531006e-4
GO:0060039 pericardium development 3.550898e-4
GO:0007059 chromosome segregation 3.813137e-4
GO:0060850 regulation of transcription involved in cell fate commitment 3.913680e-4
GO:0046544 development of secondary male sexual characteristics 3.964291e-4
GO:0045081 negative regulation of interleukin-10 biosynthetic process 3.964291e-4
GO:0051276 chromosome organization 3.973485e-4
GO:0043029 T cell homeostasis 3.978735e-4
GO:0002066 columnar/cuboidal epithelial cell development 4.021273e-4
GO:0022613 ribonucleoprotein complex biogenesis 4.081170e-4
GO:0090398 cellular senescence 4.127112e-4
GO:0010894 negative regulation of steroid biosynthetic process 4.133404e-4
GO:0010159 specification of organ position 4.136531e-4
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration 4.314909e-4
GO:0072183 negative regulation of nephron tubule epithelial cell differentiation 4.314909e-4
GO:0060487 lung epithelial cell differentiation 4.476785e-4
GO:0031120 snRNA pseudouridine synthesis 4.486199e-4
GO:0060119 inner ear receptor cell development 4.490792e-4
GO:0048806 genitalia development 4.541221e-4
GO:0035425 autocrine signaling 4.619229e-4
GO:0042698 ovulation cycle 4.668701e-4
GO:0060021 palate development 4.707627e-4
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 4.755040e-4
GO:0040019 positive regulation of embryonic development 4.766975e-4
GO:0061325 cell proliferation involved in outflow tract morphogenesis 4.902185e-4
GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis 4.902185e-4
GO:0032274 gonadotropin secretion 5.118502e-4
GO:0071824 protein-DNA complex subunit organization 5.146311e-4
GO:0071218 cellular response to misfolded protein 5.352383e-4
GO:0010501 RNA secondary structure unwinding 5.376771e-4
GO:0010564 regulation of cell cycle process 5.648631e-4
GO:0072070 loop of Henle development 5.691498e-4
GO:0001947 heart looping 5.702257e-4
GO:0033554 cellular response to stress 5.819707e-4
GO:0035966 response to topologically incorrect protein 5.831476e-4
GO:0003306 Wnt receptor signaling pathway involved in heart development 5.931107e-4
GO:0051890 regulation of cardioblast differentiation 5.979783e-4
GO:0060976 coronary vasculature development 6.010684e-4
GO:0003344 pericardium morphogenesis 6.097327e-4
GO:2000484 positive regulation of interleukin-8 secretion 6.097327e-4
GO:0044339 canonical Wnt receptor signaling pathway involved in osteoblast differentiation 6.169556e-4
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 6.169556e-4
GO:0044338 canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation 6.169556e-4
GO:0002331 pre-B cell allelic exclusion 6.169556e-4
GO:0033599 regulation of mammary gland epithelial cell proliferation 6.292400e-4
GO:2000064 regulation of cortisol biosynthetic process 6.611871e-4
GO:0042350 GDP-L-fucose biosynthetic process 6.611871e-4
GO:0006545 glycine biosynthetic process 6.611871e-4
GO:0090239 regulation of histone H4 acetylation 6.626299e-4
GO:0014057 positive regulation of acetylcholine secretion 6.626299e-4
GO:0060340 positive regulation of type I interferon-mediated signaling pathway 6.773722e-4
GO:0003206 cardiac chamber morphogenesis 6.889755e-4
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 7.034619e-4
GO:0021800 cerebral cortex tangential migration 7.034619e-4
GO:0042249 establishment of planar polarity of embryonic epithelium 7.076696e-4
GO:0009185 ribonucleoside diphosphate metabolic process 7.270495e-4
GO:0048469 cell maturation 7.439429e-4
GO:0014029 neural crest formation 7.506733e-4
GO:0030819 positive regulation of cAMP biosynthetic process 7.604583e-4
GO:0001936 regulation of endothelial cell proliferation 7.981886e-4
GO:0061337 cardiac conduction 8.211174e-4
GO:0060923 cardiac muscle cell fate commitment 8.294586e-4
GO:0009067 aspartate family amino acid biosynthetic process 8.836549e-4
GO:0008629 induction of apoptosis by intracellular signals 8.929176e-4
GO:0008354 germ cell migration 9.023365e-4
GO:0090037 positive regulation of protein kinase C signaling cascade 9.155274e-4
GO:0048539 bone marrow development 9.185338e-4
GO:0034720 histone H3-K4 demethylation 9.185338e-4
GO:2000369 regulation of clathrin-mediated endocytosis 9.321405e-4
GO:0031327 negative regulation of cellular biosynthetic process 9.371556e-4
GO:0003156 regulation of organ formation 9.575527e-4
GO:0046543 development of secondary female sexual characteristics 9.768464e-4
GO:0060430 lung saccule development 9.805614e-4
GO:0051881 regulation of mitochondrial membrane potential 9.805614e-4
GO:0003148 outflow tract septum morphogenesis 9.812870e-4
GO:0035404 histone-serine phosphorylation 1.007732e-3
GO:0007399 nervous system development 1.015339e-3
GO:0040008 regulation of growth 1.033803e-3
GO:0001539 ciliary or flagellar motility 1.096680e-3
GO:0032909 regulation of transforming growth factor beta2 production 1.100147e-3
GO:0030514 negative regulation of BMP signaling pathway 1.110748e-3
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 1.123050e-3
GO:0030968 endoplasmic reticulum unfolded protein response 1.144804e-3
GO:0021986 habenula development 1.150613e-3
GO:0072133 metanephric mesenchyme morphogenesis 1.150613e-3
GO:0030804 positive regulation of cyclic nucleotide biosynthetic process 1.224797e-3
GO:0010765 positive regulation of sodium ion transport 1.246877e-3
GO:2000615 regulation of histone H3-K9 acetylation 1.262117e-3
GO:0060574 intestinal epithelial cell maturation 1.262117e-3
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 1.262117e-3
GO:0033566 gamma-tubulin complex localization 1.262117e-3
GO:0071843 cellular component biogenesis at cellular level 1.276743e-3
GO:0016180 snRNA processing 1.316812e-3
GO:0051096 positive regulation of helicase activity 1.317897e-3
GO:0016556 mRNA modification 1.317897e-3
GO:2000679 positive regulation of transcription regulatory region DNA binding 1.327876e-3
GO:0021915 neural tube development 1.350575e-3
GO:2000242 negative regulation of reproductive process 1.354148e-3
GO:0060236 regulation of mitotic spindle organization 1.358390e-3
GO:0009235 cobalamin metabolic process 1.358390e-3
GO:0006529 asparagine biosynthetic process 1.358390e-3
GO:0055117 regulation of cardiac muscle contraction 1.389491e-3
GO:0030857 negative regulation of epithelial cell differentiation 1.439323e-3
GO:0007050 cell cycle arrest 1.442565e-3
GO:0051891 positive regulation of cardioblast differentiation 1.451267e-3
GO:0002262 myeloid cell homeostasis 1.464157e-3
GO:0051402 neuron apoptosis 1.513623e-3
GO:0060068 vagina development 1.531246e-3
GO:0045136 development of secondary sexual characteristics 1.538134e-3
GO:0021827 postnatal olfactory bulb interneuron migration 1.580168e-3
GO:0046654 tetrahydrofolate biosynthetic process 1.590979e-3
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 1.590979e-3
GO:0035584 calcium-mediated signaling using intracellular calcium source 1.590979e-3
GO:0048843 negative regulation of axon extension involved in axon guidance 1.596218e-3
GO:0042491 auditory receptor cell differentiation 1.605587e-3
GO:0060947 cardiac vascular smooth muscle cell differentiation 1.610946e-3
GO:0001843 neural tube closure 1.625359e-3
GO:0009755 hormone-mediated signaling pathway 1.626222e-3
GO:0046620 regulation of organ growth 1.641385e-3
GO:0071681 cellular response to indole-3-methanol 1.647114e-3
GO:0043482 cellular pigment accumulation 1.647114e-3
GO:0045739 positive regulation of DNA repair 1.664965e-3
GO:0060788 ectodermal placode formation 1.667832e-3
GO:0060444 branching involved in mammary gland duct morphogenesis 1.671244e-3
GO:0071425 hemopoietic stem cell proliferation 1.694614e-3
GO:0060486 Clara cell differentiation 1.701808e-3
GO:0030823 regulation of cGMP metabolic process 1.701808e-3
GO:0003006 developmental process involved in reproduction 1.750920e-3
GO:0060986 endocrine hormone secretion 1.800270e-3
GO:0010870 positive regulation of receptor biosynthetic process 1.832616e-3
GO:0006515 misfolded or incompletely synthesized protein catabolic process 1.832616e-3
GO:0003231 cardiac ventricle development 1.837103e-3
GO:0055021 regulation of cardiac muscle tissue growth 1.858468e-3
GO:0060686 negative regulation of prostatic bud formation 1.867789e-3
GO:0042471 ear morphogenesis 1.867824e-3
GO:0006998 nuclear envelope organization 1.887250e-3
GO:0045647 negative regulation of erythrocyte differentiation 1.905753e-3
GO:0070979 protein K11-linked ubiquitination 1.930180e-3
GO:2000380 regulation of mesoderm development 2.003556e-3
GO:0048852 diencephalon morphogenesis 2.003556e-3
GO:0051964 negative regulation of synapse assembly 2.025640e-3
GO:0003254 regulation of membrane depolarization 2.063438e-3
GO:0060764 cell-cell signaling involved in mammary gland development 2.121458e-3
GO:0060379 cardiac muscle cell myoblast differentiation 2.121458e-3
GO:0003127 detection of nodal flow 2.121458e-3
GO:0031129 inductive cell-cell signaling 2.121458e-3
GO:0034551 mitochondrial respiratory chain complex III assembly 2.121458e-3
GO:0030262 apoptotic nuclear change 2.130998e-3
GO:0072098 anterior/posterior pattern specification involved in kidney development 2.136514e-3
GO:0048389 intermediate mesoderm development 2.136514e-3
GO:0007412 axon target recognition 2.136514e-3
GO:0031018 endocrine pancreas development 2.158993e-3
GO:0060749 mammary gland alveolus development 2.178388e-3
GO:0060606 tube closure 2.255969e-3
GO:0046653 tetrahydrofolate metabolic process 2.285208e-3
GO:0003166 bundle of His development 2.285208e-3
GO:0035148 tube formation 2.285772e-3
GO:0034660 ncRNA metabolic process 2.300080e-3
GO:0051961 negative regulation of nervous system development 2.371330e-3
GO:0050665 hydrogen peroxide biosynthetic process 2.371330e-3
GO:0006085 acetyl-CoA biosynthetic process 2.371330e-3
GO:0051642 centrosome localization 2.389916e-3
GO:0042490 mechanoreceptor differentiation 2.396356e-3
GO:0034698 response to gonadotropin stimulus 2.422071e-3
GO:0006610 ribosomal protein import into nucleus 2.452380e-3
GO:0060045 positive regulation of cardiac muscle cell proliferation 2.459293e-3
GO:0032439 endosome localization 2.461695e-3
GO:0031104 dendrite regeneration 2.461695e-3
GO:0060603 mammary gland duct morphogenesis 2.491132e-3
GO:0050922 negative regulation of chemotaxis 2.524404e-3
GO:0051052 regulation of DNA metabolic process 2.538600e-3
GO:0000209 protein polyubiquitination 2.583064e-3
GO:0030825 positive regulation of cGMP metabolic process 2.596421e-3
GO:0072203 cell proliferation involved in metanephros development 2.596421e-3
GO:0006916 anti-apoptosis 2.610228e-3
GO:0043401 steroid hormone mediated signaling pathway 2.621624e-3
GO:0031572 G2/M transition DNA damage checkpoint 2.631613e-3
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 2.658930e-3
GO:0046755 non-lytic virus budding 2.658930e-3
GO:0000077 DNA damage checkpoint 2.703048e-3
GO:0048732 gland development 2.717465e-3
GO:0046449 creatinine metabolic process 2.729786e-3
GO:0043217 myelin maintenance 2.759584e-3
GO:0070286 axonemal dynein complex assembly 2.798895e-3
GO:0048598 embryonic morphogenesis 2.975967e-3
GO:0000413 protein peptidyl-prolyl isomerization 2.978551e-3
GO:0000710 meiotic mismatch repair 2.996302e-3
GO:0043276 anoikis 2.996302e-3
GO:0031128 developmental induction 3.090656e-3
GO:0006334 nucleosome assembly 3.141056e-3
GO:0034470 ncRNA processing 3.142927e-3
GO:0045599 negative regulation of fat cell differentiation 3.168217e-3
GO:0045766 positive regulation of angiogenesis 3.176904e-3
GO:0072166 posterior mesonephric tubule development 3.177465e-3
GO:0032347 regulation of aldosterone biosynthetic process 3.177465e-3
GO:0071044 histone mRNA catabolic process 3.193548e-3
GO:0050869 negative regulation of B cell activation 3.233030e-3
GO:0034508 centromere complex assembly 3.281084e-3
GO:0061326 renal tubule development 3.355298e-3
GO:0071480 cellular response to gamma radiation 3.428668e-3
GO:0031570 DNA integrity checkpoint 3.540049e-3
GO:0046590 embryonic leg morphogenesis 3.584821e-3
GO:0030278 regulation of ossification 3.605828e-3
GO:0001841 neural tube formation 3.712213e-3
GO:0003219 cardiac right ventricle formation 3.727504e-3
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 3.751863e-3
GO:0043487 regulation of RNA stability 3.757664e-3
GO:0006921 cellular component disassembly involved in apoptosis 3.842428e-3
GO:0009948 anterior/posterior axis specification 3.848828e-3
GO:0060113 inner ear receptor cell differentiation 3.865839e-3
GO:0008334 histone mRNA metabolic process 3.947515e-3
GO:0003061 positive regulation of the force of heart contraction by norepinephrine 3.967253e-3
GO:0060480 lung goblet cell differentiation 3.967253e-3
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development 3.967253e-3
GO:0010157 response to chlorate 3.967253e-3
GO:2000351 regulation of endothelial cell apoptosis 3.994636e-3
GO:0090102 cochlea development 4.000464e-3
GO:0006986 response to unfolded protein 4.007557e-3
GO:0048378 regulation of lateral mesodermal cell fate specification 4.036262e-3
GO:0006269 DNA replication, synthesis of RNA primer 4.036262e-3
GO:0030862 positive regulation of polarized epithelial cell differentiation 4.046883e-3
GO:0022414 reproductive process 4.105979e-3
GO:0022029 telencephalon cell migration 4.186104e-3
GO:0042981 regulation of apoptosis 4.195371e-3
GO:0060420 regulation of heart growth 4.205443e-3
GO:0043067 regulation of programmed cell death 4.247183e-3