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Novel motif:72

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name:motif72_CAGAAMC

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0002576 platelet degranulation 8.364571e-15
GO:0009611 response to wounding 8.331120e-14
GO:0001775 cell activation 7.539861e-13
GO:0006955 immune response 2.148706e-12
GO:0030241 skeletal muscle myosin thick filament assembly 4.375170e-12
GO:0007076 mitotic chromosome condensation 7.709162e-12
GO:0006952 defense response 5.178709e-11
GO:0048769 sarcomerogenesis 7.215056e-11
GO:0030168 platelet activation 1.378414e-10
GO:0007599 hemostasis 1.607562e-10
GO:0042060 wound healing 1.672471e-10
GO:0002376 immune system process 1.733694e-10
GO:0007596 blood coagulation 2.026674e-10
GO:0030185 nitric oxide transport 6.987985e-10
GO:0014866 skeletal myofibril assembly 1.576334e-9
GO:0007067 mitosis 2.631496e-9
GO:0030240 skeletal muscle thin filament assembly 2.719111e-9
GO:0019221 cytokine-mediated signaling pathway 3.160384e-9
GO:0000087 M phase of mitotic cell cycle 4.602877e-9
GO:0000279 M phase 4.627049e-9
GO:0070252 actin-mediated cell contraction 4.950787e-9
GO:0030049 muscle filament sliding 5.800229e-9
GO:0030421 defecation 9.583524e-9
GO:0006950 response to stress 3.260399e-8
GO:0030048 actin filament-based movement 4.110668e-8
GO:0007614 short-term memory 4.154354e-8
GO:0048285 organelle fission 5.476570e-8
GO:0050878 regulation of body fluid levels 5.795216e-8
GO:0032101 regulation of response to external stimulus 7.266213e-8
GO:0015671 oxygen transport 8.505451e-8
GO:0000070 mitotic sister chromatid segregation 1.004696e-7
GO:0050715 positive regulation of cytokine secretion 1.390612e-7
GO:0033555 multicellular organismal response to stress 1.408231e-7
GO:0043550 regulation of lipid kinase activity 1.487638e-7
GO:0007015 actin filament organization 1.496018e-7
GO:0000819 sister chromatid segregation 1.628814e-7
GO:0033003 regulation of mast cell activation 1.736080e-7
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 2.098824e-7
GO:0048739 cardiac muscle fiber development 2.180786e-7
GO:0055013 cardiac muscle cell development 2.185623e-7
GO:0034097 response to cytokine stimulus 2.431207e-7
GO:0006768 biotin metabolic process 2.854724e-7
GO:0002407 dendritic cell chemotaxis 3.537005e-7
GO:0055003 cardiac myofibril assembly 3.762955e-7
GO:0003012 muscle system process 4.295594e-7
GO:0006486 protein glycosylation 5.683882e-7
GO:0006936 muscle contraction 6.242400e-7
GO:0050680 negative regulation of epithelial cell proliferation 6.453044e-7
GO:0042221 response to chemical stimulus 8.933556e-7
GO:0006364 rRNA processing 1.010732e-6
GO:0070085 glycosylation 1.115578e-6
GO:0032940 secretion by cell 1.196874e-6
GO:0006887 exocytosis 1.278567e-6
GO:0022402 cell cycle process 1.303088e-6
GO:0031100 organ regeneration 1.390107e-6
GO:0021629 olfactory nerve structural organization 1.447732e-6
GO:0071844 cellular component assembly at cellular level 1.516677e-6
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1.588196e-6
GO:0071345 cellular response to cytokine stimulus 1.626292e-6
GO:0030595 leukocyte chemotaxis 1.732453e-6
GO:0034063 stress granule assembly 2.203561e-6
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 2.264853e-6
GO:0007166 cell surface receptor linked signaling pathway 2.482069e-6
GO:0050795 regulation of behavior 2.742419e-6
GO:0006688 glycosphingolipid biosynthetic process 3.031338e-6
GO:0048266 behavioral response to pain 3.175386e-6
GO:0051592 response to calcium ion 3.259608e-6
GO:0016072 rRNA metabolic process 3.358042e-6
GO:0031347 regulation of defense response 3.396677e-6
GO:0030261 chromosome condensation 3.544653e-6
GO:0000414 regulation of histone H3-K36 methylation 4.125115e-6
GO:0050707 regulation of cytokine secretion 4.169176e-6
GO:0031929 TOR signaling cascade 5.052302e-6
GO:0050896 response to stimulus 5.456848e-6
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 5.486681e-6
GO:0042320 regulation of circadian sleep/wake cycle, REM sleep 5.618474e-6
GO:0050714 positive regulation of protein secretion 5.734482e-6
GO:0090218 positive regulation of lipid kinase activity 5.836600e-6
GO:0006335 DNA replication-dependent nucleosome assembly 6.718827e-6
GO:0042178 xenobiotic catabolic process 7.584349e-6
GO:0000416 positive regulation of histone H3-K36 methylation 7.713001e-6
GO:0006552 leucine catabolic process 7.767173e-6
GO:0051338 regulation of transferase activity 7.900220e-6
GO:0009101 glycoprotein biosynthetic process 1.220387e-5
GO:0042254 ribosome biogenesis 1.329400e-5
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 1.347649e-5
GO:0033993 response to lipid 1.423170e-5
GO:0016525 negative regulation of angiogenesis 1.507958e-5
GO:0009100 glycoprotein metabolic process 1.556302e-5
GO:0043623 cellular protein complex assembly 1.668829e-5
GO:0007186 G-protein coupled receptor protein signaling pathway 1.691710e-5
GO:0030277 maintenance of gastrointestinal epithelium 1.706200e-5
GO:0060693 regulation of branching involved in salivary gland morphogenesis 1.823299e-5
GO:0071841 cellular component organization or biogenesis at cellular level 1.989595e-5
GO:0007584 response to nutrient 2.159137e-5
GO:0043549 regulation of kinase activity 2.280801e-5
GO:0048535 lymph node development 2.509289e-5
GO:0042596 fear response 2.616659e-5
GO:0046903 secretion 2.670252e-5
GO:0007613 memory 2.766041e-5
GO:0009566 fertilization 2.840161e-5
GO:0045214 sarcomere organization 3.012463e-5
GO:0019216 regulation of lipid metabolic process 3.088908e-5
GO:0050790 regulation of catalytic activity 3.092018e-5
GO:0032846 positive regulation of homeostatic process 3.236414e-5
GO:0071034 CUT catabolic process 3.488149e-5
GO:0035414 negative regulation of catenin import into nucleus 3.669759e-5
GO:0006928 cellular component movement 4.015129e-5
GO:0007338 single fertilization 4.033019e-5
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 4.238037e-5
GO:0050983 deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase 4.272367e-5
GO:0051445 regulation of meiotic cell cycle 4.566348e-5
GO:0001574 ganglioside biosynthetic process 4.702535e-5
GO:0042744 hydrogen peroxide catabolic process 4.776355e-5
GO:0080134 regulation of response to stress 5.215783e-5
GO:0048747 muscle fiber development 5.447146e-5
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 5.677368e-5
GO:0051384 response to glucocorticoid stimulus 5.718162e-5
GO:0015669 gas transport 5.744953e-5
GO:0022613 ribonucleoprotein complex biogenesis 5.778636e-5
GO:0046426 negative regulation of JAK-STAT cascade 5.809610e-5
GO:0040020 regulation of meiosis 5.869069e-5
GO:0071934 thiamine transmembrane transport 6.197552e-5
GO:0046491 L-methylmalonyl-CoA metabolic process 6.197552e-5
GO:0002682 regulation of immune system process 6.587092e-5
GO:0060675 ureteric bud morphogenesis 6.590714e-5
GO:0007049 cell cycle 6.614833e-5
GO:0007018 microtubule-based movement 6.798624e-5
GO:0032367 intracellular cholesterol transport 7.809081e-5
GO:0050779 RNA destabilization 7.870482e-5
GO:0000086 G2/M transition of mitotic cell cycle 8.112537e-5
GO:0045859 regulation of protein kinase activity 8.329317e-5
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 8.724397e-5
GO:0008354 germ cell migration 8.755668e-5
GO:0006968 cellular defense response 9.565227e-5
GO:0002694 regulation of leukocyte activation 9.596677e-5
GO:0060084 synaptic transmission involved in micturition 9.843643e-5
GO:0014048 regulation of glutamate secretion 9.886248e-5
GO:0006551 leucine metabolic process 1.028685e-4
GO:0030534 adult behavior 1.036564e-4
GO:0043302 positive regulation of leukocyte degranulation 1.040799e-4
GO:0051902 negative regulation of mitochondrial depolarization 1.067831e-4
GO:0048008 platelet-derived growth factor receptor signaling pathway 1.072754e-4
GO:0050865 regulation of cell activation 1.106350e-4
GO:0034723 DNA replication-dependent nucleosome organization 1.107750e-4
GO:0007050 cell cycle arrest 1.175508e-4
GO:0048679 regulation of axon regeneration 1.183177e-4
GO:0009607 response to biotic stimulus 1.203239e-4
GO:0007259 JAK-STAT cascade 1.207671e-4
GO:0065009 regulation of molecular function 1.217537e-4
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity 1.248763e-4
GO:0030321 transepithelial chloride transport 1.255058e-4
GO:0031667 response to nutrient levels 1.307975e-4
GO:0001658 branching involved in ureteric bud morphogenesis 1.357696e-4
GO:0034699 response to luteinizing hormone stimulus 1.374342e-4
GO:0010035 response to inorganic substance 1.407447e-4
GO:0001831 trophectodermal cellular morphogenesis 1.452688e-4
GO:0002443 leukocyte mediated immunity 1.476314e-4
GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep 1.548894e-4
GO:0051085 chaperone mediated protein folding requiring cofactor 1.728297e-4
GO:0033235 positive regulation of protein sumoylation 1.728297e-4
GO:0010633 negative regulation of epithelial cell migration 1.759048e-4
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 1.780650e-4
GO:0008216 spermidine metabolic process 1.796530e-4
GO:0051017 actin filament bundle assembly 1.836328e-4
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 1.874981e-4
GO:0048070 regulation of developmental pigmentation 1.879598e-4
GO:0032103 positive regulation of response to external stimulus 1.945981e-4
GO:0034126 positive regulation of MyD88-dependent toll-like receptor signaling pathway 2.012897e-4
GO:0051047 positive regulation of secretion 2.052550e-4
GO:0032844 regulation of homeostatic process 2.056025e-4
GO:0051240 positive regulation of multicellular organismal process 2.063749e-4
GO:0002118 aggressive behavior 2.130283e-4
GO:0051336 regulation of hydrolase activity 2.177160e-4
GO:0033006 regulation of mast cell activation involved in immune response 2.189084e-4
GO:0048584 positive regulation of response to stimulus 2.258682e-4
GO:0031581 hemidesmosome assembly 2.273691e-4
GO:0021553 olfactory nerve development 2.290158e-4
GO:0002696 positive regulation of leukocyte activation 2.379547e-4
GO:0045087 innate immune response 2.390257e-4
GO:0031032 actomyosin structure organization 2.426908e-4
GO:0033522 histone H2A ubiquitination 2.539289e-4
GO:0007029 endoplasmic reticulum organization 2.549082e-4
GO:0043306 positive regulation of mast cell degranulation 2.559565e-4
GO:0034661 ncRNA catabolic process 2.593183e-4
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 2.604828e-4
GO:0008361 regulation of cell size 2.654197e-4
GO:0030224 monocyte differentiation 2.666134e-4
GO:0042572 retinol metabolic process 2.673668e-4
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.711624e-4
GO:0007096 regulation of exit from mitosis 2.782285e-4
GO:0006582 melanin metabolic process 2.800815e-4
GO:0051297 centrosome organization 2.917104e-4
GO:0031023 microtubule organizing center organization 2.989289e-4
GO:0008628 induction of apoptosis by hormones 2.989951e-4
GO:0050708 regulation of protein secretion 3.001245e-4
GO:0022600 digestive system process 3.053389e-4
GO:0042508 tyrosine phosphorylation of Stat1 protein 3.125428e-4
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 3.148007e-4
GO:0006721 terpenoid metabolic process 3.168625e-4
GO:0016101 diterpenoid metabolic process 3.187436e-4
GO:0050764 regulation of phagocytosis 3.249075e-4
GO:0006776 vitamin A metabolic process 3.386508e-4
GO:0048512 circadian behavior 3.390918e-4
GO:0001523 retinoid metabolic process 3.449626e-4
GO:0030239 myofibril assembly 3.467723e-4
GO:0006921 cellular component disassembly involved in apoptosis 3.486751e-4
GO:0051322 anaphase 3.504034e-4
GO:0048583 regulation of response to stimulus 3.527583e-4
GO:0043300 regulation of leukocyte degranulation 3.542425e-4
GO:0010523 negative regulation of calcium ion transport into cytosol 3.546288e-4
GO:0046685 response to arsenic-containing substance 3.564759e-4
GO:0042982 amyloid precursor protein metabolic process 3.569411e-4
GO:0006711 estrogen catabolic process 3.583951e-4
GO:0071843 cellular component biogenesis at cellular level 3.610503e-4
GO:0034622 cellular macromolecular complex assembly 3.613914e-4
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 3.638628e-4
GO:0050920 regulation of chemotaxis 3.921551e-4
GO:0048554 positive regulation of metalloenzyme activity 3.991065e-4
GO:0000090 mitotic anaphase 4.022333e-4
GO:0008624 induction of apoptosis by extracellular signals 4.094165e-4
GO:0046425 regulation of JAK-STAT cascade 4.198189e-4
GO:0030325 adrenal gland development 4.224886e-4
GO:0009726 detection of endogenous stimulus 4.310135e-4
GO:0035461 vitamin transmembrane transport 4.428847e-4
GO:0050867 positive regulation of cell activation 4.452798e-4
GO:0000188 inactivation of MAPK activity 4.558132e-4
GO:0035048 splicing factor protein import into nucleus 4.656054e-4
GO:0042921 glucocorticoid receptor signaling pathway 4.743326e-4
GO:0050818 regulation of coagulation 4.765987e-4
GO:0009888 tissue development 4.808912e-4
GO:0009214 cyclic nucleotide catabolic process 4.813089e-4
GO:0009615 response to virus 4.838215e-4
GO:0042325 regulation of phosphorylation 4.840096e-4
GO:0002268 follicular dendritic cell differentiation 4.843623e-4
GO:0032287 peripheral nervous system myelin maintenance 4.848505e-4
GO:0014889 muscle atrophy 4.880649e-4
GO:0042506 tyrosine phosphorylation of Stat5 protein 5.060898e-4
GO:0007626 locomotory behavior 5.179069e-4
GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein 5.185737e-4
GO:0048521 negative regulation of behavior 5.216069e-4
GO:0051302 regulation of cell division 5.216905e-4
GO:0019220 regulation of phosphate metabolic process 5.223971e-4
GO:0001824 blastocyst development 5.240859e-4
GO:0007406 negative regulation of neuroblast proliferation 5.307351e-4
GO:0001662 behavioral fear response 5.441684e-4
GO:0033005 positive regulation of mast cell activation 5.453758e-4
GO:0002886 regulation of myeloid leukocyte mediated immunity 5.584696e-4
GO:0008284 positive regulation of cell proliferation 5.590001e-4
GO:0042438 melanin biosynthetic process 5.629952e-4
GO:0045835 negative regulation of meiosis 5.650879e-4
GO:0006290 pyrimidine dimer repair 5.729703e-4
GO:0006954 inflammatory response 5.855769e-4
GO:0009247 glycolipid biosynthetic process 5.858546e-4
GO:0021846 cell proliferation in forebrain 5.862024e-4
GO:0061028 establishment of endothelial barrier 6.147010e-4
GO:0031099 regeneration 6.179894e-4
GO:0006941 striated muscle contraction 6.340019e-4
GO:0022403 cell cycle phase 6.397383e-4
GO:0002699 positive regulation of immune effector process 6.517661e-4
GO:0045187 regulation of circadian sleep/wake cycle, sleep 6.672584e-4
GO:0021847 ventricular zone neuroblast division 6.686735e-4
GO:0050922 negative regulation of chemotaxis 6.703965e-4
GO:0016064 immunoglobulin mediated immune response 6.722565e-4
GO:0043217 myelin maintenance 6.789967e-4
GO:0048520 positive regulation of behavior 6.803074e-4
GO:0046732 active induction of host immune response by virus 6.869798e-4
GO:0050776 regulation of immune response 6.895715e-4
GO:0006720 isoprenoid metabolic process 6.973543e-4
GO:0043090 amino acid import 7.015502e-4
GO:0035066 positive regulation of histone acetylation 7.073404e-4
GO:0042745 circadian sleep/wake cycle 7.095132e-4
GO:0032571 response to vitamin K 7.299480e-4
GO:0071840 cellular component organization or biogenesis 7.443146e-4
GO:0019724 B cell mediated immunity 7.476799e-4
GO:0042753 positive regulation of circadian rhythm 7.492510e-4
GO:0050819 negative regulation of coagulation 7.510548e-4
GO:0002675 positive regulation of acute inflammatory response 7.684562e-4
GO:0060326 cell chemotaxis 7.757882e-4
GO:0034754 cellular hormone metabolic process 7.780926e-4
GO:0031468 nuclear envelope reassembly 7.785922e-4
GO:0007100 mitotic centrosome separation 7.785922e-4
GO:0003008 system process 7.830591e-4
GO:0071842 cellular component organization at cellular level 7.869147e-4
GO:0043627 response to estrogen stimulus 8.017685e-4
GO:0009605 response to external stimulus 8.053867e-4
GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus 8.160821e-4
GO:0071731 response to nitric oxide 8.222247e-4
GO:0051707 response to other organism 8.269113e-4
GO:0010742 macrophage derived foam cell differentiation 8.350743e-4
GO:0035695 mitochondrion degradation by induced vacuole formation 8.442218e-4
GO:0001881 receptor recycling 8.527784e-4
GO:0032102 negative regulation of response to external stimulus 8.697466e-4
GO:0022410 circadian sleep/wake cycle process 8.729894e-4
GO:0002209 behavioral defense response 8.779331e-4
GO:0002684 positive regulation of immune system process 8.833619e-4
GO:0001932 regulation of protein phosphorylation 8.837912e-4
GO:0031960 response to corticosteroid stimulus 8.909273e-4
GO:0030029 actin filament-based process 9.039647e-4
GO:0035039 male pronucleus assembly 9.096413e-4
GO:0046069 cGMP catabolic process 9.197861e-4
GO:0045346 regulation of MHC class II biosynthetic process 9.361271e-4
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 9.714550e-4
GO:0055007 cardiac muscle cell differentiation 9.825420e-4
GO:0007586 digestion 9.862115e-4
GO:0019932 second-messenger-mediated signaling 9.880983e-4
GO:0044330 canonical Wnt receptor signaling pathway involved in positive regulation of wound healing 9.913229e-4
GO:0044328 canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration 9.913229e-4
GO:0044329 canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion 9.913229e-4
GO:0051235 maintenance of location 9.935277e-4
GO:0032501 multicellular organismal process 9.961180e-4
GO:0007416 synapse assembly 1.005390e-3
GO:0042742 defense response to bacterium 1.006141e-3
GO:0050727 regulation of inflammatory response 1.024946e-3
GO:0006598 polyamine catabolic process 1.026985e-3
GO:0050900 leukocyte migration 1.028195e-3
GO:0033159 negative regulation of protein import into nucleus, translocation 1.053248e-3
GO:0060600 dichotomous subdivision of an epithelial terminal unit 1.056254e-3
GO:0051347 positive regulation of transferase activity 1.070183e-3
GO:0060356 leucine import 1.129040e-3
GO:0006508 proteolysis 1.134900e-3
GO:0032507 maintenance of protein location in cell 1.137851e-3
GO:0034621 cellular macromolecular complex subunit organization 1.147311e-3
GO:0051480 cytosolic calcium ion homeostasis 1.192446e-3
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development 1.205729e-3
GO:0009991 response to extracellular stimulus 1.209186e-3
GO:0017187 peptidyl-glutamic acid carboxylation 1.214955e-3
GO:0045347 negative regulation of MHC class II biosynthetic process 1.216965e-3
GO:0002526 acute inflammatory response 1.217757e-3
GO:0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction 1.222231e-3
GO:0031622 positive regulation of fever generation 1.255279e-3
GO:0044085 cellular component biogenesis 1.273145e-3
GO:0070171 negative regulation of tooth mineralization 1.279747e-3
GO:0031120 snRNA pseudouridine synthesis 1.294874e-3
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 1.294874e-3
GO:0045911 positive regulation of DNA recombination 1.295732e-3
GO:0010743 regulation of macrophage derived foam cell differentiation 1.298781e-3
GO:0045948 positive regulation of translational initiation 1.315981e-3
GO:0007010 cytoskeleton organization 1.320037e-3
GO:0010837 regulation of keratinocyte proliferation 1.328623e-3
GO:0043116 negative regulation of vascular permeability 1.335378e-3
GO:0051279 regulation of release of sequestered calcium ion into cytosol 1.337992e-3
GO:0034112 positive regulation of homotypic cell-cell adhesion 1.347319e-3
GO:0048545 response to steroid hormone stimulus 1.375814e-3
GO:0010632 regulation of epithelial cell migration 1.376965e-3
GO:0010669 epithelial structure maintenance 1.379431e-3
GO:0048265 response to pain 1.384570e-3
GO:0010466 negative regulation of peptidase activity 1.389700e-3
GO:0007156 homophilic cell adhesion 1.405599e-3
GO:0002449 lymphocyte mediated immunity 1.414785e-3
GO:0030593 neutrophil chemotaxis 1.416167e-3
GO:0030148 sphingolipid biosynthetic process 1.423240e-3
GO:0006775 fat-soluble vitamin metabolic process 1.429213e-3
GO:0006198 cAMP catabolic process 1.489510e-3
GO:0043368 positive T cell selection 1.489846e-3
GO:0007343 egg activation 1.494706e-3
GO:0045321 leukocyte activation 1.495139e-3
GO:0051649 establishment of localization in cell 1.495949e-3
GO:0043112 receptor metabolic process 1.582917e-3
GO:0042119 neutrophil activation 1.599530e-3
GO:0010951 negative regulation of endopeptidase activity 1.605798e-3
GO:2000178 negative regulation of neural precursor cell proliferation 1.635854e-3
GO:0043304 regulation of mast cell degranulation 1.635854e-3
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 1.636181e-3
GO:0045213 neurotransmitter receptor metabolic process 1.639277e-3
GO:0071344 diphosphate metabolic process 1.653747e-3
GO:0006493 protein O-linked glycosylation 1.655804e-3
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 1.655968e-3
GO:0033674 positive regulation of kinase activity 1.680764e-3
GO:0060594 mammary gland specification 1.707965e-3
GO:0050907 detection of chemical stimulus involved in sensory perception 1.729405e-3
GO:0045780 positive regulation of bone resorption 1.749883e-3
GO:0010310 regulation of hydrogen peroxide metabolic process 1.753226e-3
GO:0001657 ureteric bud development 1.792392e-3
GO:0050919 negative chemotaxis 1.796671e-3
GO:0034145 positive regulation of toll-like receptor 4 signaling pathway 1.798852e-3
GO:0045058 T cell selection 1.803518e-3
GO:0007274 neuromuscular synaptic transmission 1.821040e-3
GO:0055099 response to high density lipoprotein particle stimulus 1.823154e-3
GO:0016075 rRNA catabolic process 1.823154e-3
GO:0014894 response to denervation involved in regulation of muscle adaptation 1.836136e-3
GO:0002573 myeloid leukocyte differentiation 1.872074e-3
GO:0010522 regulation of calcium ion transport into cytosol 1.881369e-3
GO:0008593 regulation of Notch signaling pathway 1.884193e-3
GO:0050808 synapse organization 1.885952e-3
GO:0031508 centromeric heterochromatin formation 1.907083e-3
GO:0055008 cardiac muscle tissue morphogenesis 1.907821e-3
GO:0071241 cellular response to inorganic substance 1.912729e-3
GO:0071887 leukocyte apoptosis 1.941164e-3
GO:0035235 ionotropic glutamate receptor signaling pathway 1.963143e-3
GO:0032801 receptor catabolic process 1.976213e-3
GO:0051938 L-glutamate import 2.000630e-3
GO:0000278 mitotic cell cycle 2.007062e-3
GO:0045638 negative regulation of myeloid cell differentiation 2.007489e-3
GO:0031958 corticosteroid receptor signaling pathway 2.026021e-3
GO:0044003 modification by symbiont of host morphology or physiology 2.053184e-3
GO:0007181 transforming growth factor beta receptor complex assembly 2.084819e-3
GO:0007610 behavior 2.106683e-3
GO:0007165 signal transduction 2.119592e-3
GO:0007176 regulation of epidermal growth factor-activated receptor activity 2.129685e-3
GO:0018916 nitrobenzene metabolic process 2.130086e-3
GO:0009399 nitrogen fixation 2.130086e-3
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 2.149857e-3
GO:0070286 axonemal dynein complex assembly 2.169994e-3
GO:0009125 nucleoside monophosphate catabolic process 2.205439e-3
GO:0031652 positive regulation of heat generation 2.230304e-3
GO:0006323 DNA packaging 2.267442e-3
GO:0016192 vesicle-mediated transport 2.326177e-3
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 2.364598e-3
GO:0061017 hepatoblast differentiation 2.364775e-3
GO:0071103 DNA conformation change 2.384721e-3
GO:0050783 cocaine metabolic process 2.422270e-3
GO:0007275 multicellular organismal development 2.450259e-3
GO:0061387 regulation of extent of cell growth 2.460656e-3
GO:0018108 peptidyl-tyrosine phosphorylation 2.487553e-3
GO:0060713 labyrinthine layer morphogenesis 2.524109e-3
GO:0007017 microtubule-based process 2.558132e-3
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 2.569499e-3
GO:0014874 response to stimulus involved in regulation of muscle adaptation 2.569499e-3
GO:0051258 protein polymerization 2.601171e-3
GO:0042503 tyrosine phosphorylation of Stat3 protein 2.636874e-3
GO:0015918 sterol transport 2.638356e-3
GO:0045861 negative regulation of proteolysis 2.640213e-3
GO:0001906 cell killing 2.669875e-3
GO:0010511 regulation of phosphatidylinositol biosynthetic process 2.683498e-3
GO:0046434 organophosphate catabolic process 2.688632e-3
GO:0030301 cholesterol transport 2.717436e-3
GO:0010656 negative regulation of muscle cell apoptosis 2.718341e-3
GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 2.719167e-3
GO:0009817 defense response to fungus, incompatible interaction 2.719167e-3
GO:0019836 hemolysis by symbiont of host erythrocytes 2.723859e-3
GO:0010935 regulation of macrophage cytokine production 2.728959e-3
GO:0010535 positive regulation of activation of JAK2 kinase activity 2.736094e-3
GO:0044093 positive regulation of molecular function 2.769655e-3
GO:0010587 miRNA catabolic process 2.774347e-3
GO:0051054 positive regulation of DNA metabolic process 2.781254e-3
GO:0051345 positive regulation of hydrolase activity 2.789278e-3
GO:0010038 response to metal ion 2.854944e-3
GO:0048638 regulation of developmental growth 2.861990e-3
GO:0043406 positive regulation of MAP kinase activity 2.868310e-3
GO:0009408 response to heat 2.950498e-3
GO:0071712 ER-associated misfolded protein catabolic process 2.971405e-3
GO:0048387 negative regulation of retinoic acid receptor signaling pathway 2.980094e-3
GO:0031116 positive regulation of microtubule polymerization 2.980094e-3
GO:0010667 negative regulation of cardiac muscle cell apoptosis 3.006596e-3
GO:0032845 negative regulation of homeostatic process 3.023429e-3
GO:0001934 positive regulation of protein phosphorylation 3.032215e-3
GO:0007213 muscarinic acetylcholine receptor signaling pathway 3.070696e-3
GO:0012501 programmed cell death 3.099637e-3
GO:0046102 inosine metabolic process 3.108938e-3
GO:0007622 rhythmic behavior 3.109903e-3
GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein 3.146951e-3
GO:0043402 glucocorticoid mediated signaling pathway 3.176593e-3
GO:0017121 phospholipid scrambling 3.186506e-3
GO:0051883 killing of cells in other organism involved in symbiotic interaction 3.195795e-3
GO:0043500 muscle adaptation 3.222421e-3
GO:0033209 tumor necrosis factor-mediated signaling pathway 3.245969e-3
GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 3.260572e-3
GO:0030162 regulation of proteolysis 3.285684e-3
GO:0070305 response to cGMP 3.291537e-3
GO:0010536 positive regulation of activation of Janus kinase activity 3.291537e-3
GO:0021869 forebrain ventricular zone progenitor cell division 3.305995e-3
GO:0046649 lymphocyte activation 3.330927e-3
GO:0034141 positive regulation of toll-like receptor 3 signaling pathway 3.341905e-3
GO:2000639 negative regulation of SREBP-mediated signaling pathway 3.397998e-3
GO:2000346 negative regulation of hepatocyte proliferation 3.397998e-3
GO:0010745 negative regulation of macrophage derived foam cell differentiation 3.486476e-3
GO:0010800 positive regulation of peptidyl-threonine phosphorylation 3.500304e-3
GO:0006857 oligopeptide transport 3.506348e-3
GO:0050771 negative regulation of axonogenesis 3.530318e-3
GO:0007157 heterophilic cell-cell adhesion 3.532376e-3
GO:0033962 cytoplasmic mRNA processing body assembly 3.641527e-3
GO:0006888 ER to Golgi vesicle-mediated transport 3.650952e-3
GO:0007204 elevation of cytosolic calcium ion concentration 3.675217e-3
GO:0071902 positive regulation of protein serine/threonine kinase activity 3.681328e-3
GO:0048075 positive regulation of eye pigmentation 3.702412e-3
GO:0048691 positive regulation of axon extension involved in regeneration 3.702412e-3
GO:0019056 modulation by virus of host transcription 3.702412e-3
GO:0030518 steroid hormone receptor signaling pathway 3.708413e-3
GO:0019058 viral infectious cycle 3.719275e-3
GO:0031110 regulation of microtubule polymerization or depolymerization 3.737670e-3
GO:0000720 pyrimidine dimer repair by nucleotide-excision repair 3.760571e-3
GO:0010996 response to auditory stimulus 3.760571e-3
GO:0045185 maintenance of protein location 3.797648e-3
GO:0048880 sensory system development 3.845207e-3
GO:0050892 intestinal absorption 3.901576e-3
GO:0032455 nerve growth factor processing 3.950456e-3
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 3.950456e-3
GO:0002768 immune response-regulating cell surface receptor signaling pathway 3.963371e-3
GO:0071321 cellular response to cGMP 3.977777e-3
GO:0046148 pigment biosynthetic process 3.982633e-3
GO:0043085 positive regulation of catalytic activity 4.028877e-3
GO:0045907 positive regulation of vasoconstriction 4.034376e-3
GO:0043420 anthranilate metabolic process 4.056612e-3
GO:0034516 response to vitamin B6 4.056612e-3
GO:0051045 negative regulation of membrane protein ectodomain proteolysis 4.128146e-3
GO:0015817 histidine transport 4.131512e-3
GO:0046856 phosphatidylinositol dephosphorylation 4.135847e-3
GO:0048087 positive regulation of developmental pigmentation 4.147384e-3
GO:0045879 negative regulation of smoothened signaling pathway 4.168179e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0010715 regulation of extracellular matrix disassembly 2.083192e-8
GO:0042069 regulation of catecholamine metabolic process 2.083192e-8
GO:0006950 response to stress 2.635627e-8
GO:0007612 learning 4.085345e-8
GO:0008306 associative learning 4.937856e-8
GO:0042053 regulation of dopamine metabolic process 8.117494e-8
GO:0035634 response to stilbenoid 3.804171e-7
GO:0042060 wound healing 9.041311e-7
GO:0035106 operant conditioning 1.106883e-6
GO:0070474 positive regulation of uterine smooth muscle contraction 1.126862e-6
GO:0060841 venous blood vessel development 1.199882e-6
GO:0009611 response to wounding 1.333613e-6
GO:0055090 acylglycerol homeostasis 2.136911e-6
GO:0031424 keratinization 2.596099e-6
GO:0002209 behavioral defense response 3.119598e-6
GO:0006952 defense response 3.644040e-6
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 3.761329e-6
GO:0001662 behavioral fear response 4.214556e-6
GO:0042596 fear response 4.260129e-6
GO:0016998 cell wall macromolecule catabolic process 4.319579e-6
GO:0042744 hydrogen peroxide catabolic process 4.550486e-6
GO:0000722 telomere maintenance via recombination 4.684654e-6
GO:0000028 ribosomal small subunit assembly 5.354156e-6
GO:0010765 positive regulation of sodium ion transport 6.970436e-6
GO:0045760 positive regulation of action potential 8.480927e-6
GO:0002286 T cell activation involved in immune response 8.541377e-6
GO:0010466 negative regulation of peptidase activity 9.760276e-6
GO:0033555 multicellular organismal response to stress 1.020909e-5
GO:0034441 plasma lipoprotein particle oxidation 1.054976e-5
GO:0048149 behavioral response to ethanol 1.122660e-5
GO:0034599 cellular response to oxidative stress 1.205912e-5
GO:0043270 positive regulation of ion transport 1.220775e-5
GO:0050668 positive regulation of homocysteine metabolic process 1.292277e-5
GO:0045963 negative regulation of dopamine metabolic process 1.292277e-5
GO:0071702 organic substance transport 1.314792e-5
GO:0045087 innate immune response 1.581103e-5
GO:0002238 response to molecule of fungal origin 1.905854e-5
GO:0034442 regulation of lipoprotein oxidation 1.922051e-5
GO:0048845 venous blood vessel morphogenesis 2.074170e-5
GO:0072148 epithelial cell fate commitment 2.074170e-5
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 2.124157e-5
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 2.218522e-5
GO:0030836 positive regulation of actin filament depolymerization 2.289297e-5
GO:0019934 cGMP-mediated signaling 2.727528e-5
GO:0051409 response to nitrosative stress 2.775652e-5
GO:0010632 regulation of epithelial cell migration 3.302491e-5
GO:0070301 cellular response to hydrogen peroxide 3.378419e-5
GO:0006188 IMP biosynthetic process 3.432235e-5
GO:0031123 RNA 3'-end processing 3.767580e-5
GO:0050748 negative regulation of lipoprotein metabolic process 3.958396e-5
GO:0001659 temperature homeostasis 3.971757e-5
GO:0070842 aggresome assembly 4.292718e-5
GO:0044062 regulation of excretion 4.387368e-5
GO:0007611 learning or memory 4.642159e-5
GO:0002540 leukotriene production involved in inflammatory response 4.661748e-5
GO:0030799 regulation of cyclic nucleotide metabolic process 4.716777e-5
GO:0032241 positive regulation of nucleobase-containing compound transport 4.759126e-5
GO:0051176 positive regulation of sulfur metabolic process 4.999476e-5
GO:0010716 negative regulation of extracellular matrix disassembly 4.999476e-5
GO:0007219 Notch signaling pathway 5.048809e-5
GO:0007186 G-protein coupled receptor protein signaling pathway 5.235262e-5
GO:0001945 lymph vessel development 5.547816e-5
GO:0045648 positive regulation of erythrocyte differentiation 5.931974e-5
GO:0065009 regulation of molecular function 6.097689e-5
GO:0043252 sodium-independent organic anion transport 6.542246e-5
GO:0002702 positive regulation of production of molecular mediator of immune response 6.612613e-5
GO:0046958 nonassociative learning 6.739072e-5
GO:0009956 radial pattern formation 6.861977e-5
GO:0048521 negative regulation of behavior 6.866451e-5
GO:0019932 second-messenger-mediated signaling 7.531756e-5
GO:0050896 response to stimulus 7.974188e-5
GO:0070368 positive regulation of hepatocyte differentiation 8.010175e-5
GO:0060836 lymphatic endothelial cell differentiation 8.077244e-5
GO:0045639 positive regulation of myeloid cell differentiation 8.097187e-5
GO:0070846 Hsp90 deacetylation 8.659958e-5
GO:0090042 tubulin deacetylation 8.659958e-5
GO:0051961 negative regulation of nervous system development 8.788399e-5
GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment 9.212808e-5
GO:0060193 positive regulation of lipase activity 9.569671e-5
GO:0006189 'de novo' IMP biosynthetic process 1.055314e-4
GO:0051893 regulation of focal adhesion assembly 1.069855e-4
GO:0006620 posttranslational protein targeting to membrane 1.070630e-4
GO:0003008 system process 1.131708e-4
GO:0015872 dopamine transport 1.142155e-4
GO:0060157 urinary bladder development 1.168439e-4
GO:0048843 negative regulation of axon extension involved in axon guidance 1.168439e-4
GO:0034635 glutathione transport 1.169282e-4
GO:0033238 regulation of cellular amine metabolic process 1.183912e-4
GO:0032229 negative regulation of synaptic transmission, GABAergic 1.223604e-4
GO:0032924 activin receptor signaling pathway 1.269156e-4
GO:0044092 negative regulation of molecular function 1.341991e-4
GO:0032239 regulation of nucleobase-containing compound transport 1.479158e-4
GO:0003093 regulation of glomerular filtration 1.528116e-4
GO:0006982 response to lipid hydroperoxide 1.539103e-4
GO:0060055 angiogenesis involved in wound healing 1.580233e-4
GO:0045446 endothelial cell differentiation 1.584347e-4
GO:0060839 endothelial cell fate commitment 1.618091e-4
GO:0019370 leukotriene biosynthetic process 1.637668e-4
GO:0060578 superior vena cava morphogenesis 1.646520e-4
GO:0035229 positive regulation of glutamate-cysteine ligase activity 1.646520e-4
GO:0008616 queuosine biosynthetic process 1.709767e-4
GO:0030814 regulation of cAMP metabolic process 1.744412e-4
GO:0032674 regulation of interleukin-5 production 1.887882e-4
GO:0050890 cognition 1.995740e-4
GO:0090196 regulation of chemokine secretion 2.011097e-4
GO:0034340 response to type I interferon 2.011695e-4
GO:0042772 DNA damage response, signal transduction resulting in transcription 2.012999e-4
GO:0003350 pulmonary myocardium development 2.075281e-4
GO:0006637 acyl-CoA metabolic process 2.231821e-4
GO:0051973 positive regulation of telomerase activity 2.251703e-4
GO:0051346 negative regulation of hydrolase activity 2.273062e-4
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 2.280953e-4
GO:0003158 endothelium development 2.309158e-4
GO:0051289 protein homotetramerization 2.419342e-4
GO:0006812 cation transport 2.518448e-4
GO:0042221 response to chemical stimulus 2.525829e-4
GO:0042743 hydrogen peroxide metabolic process 2.553535e-4
GO:0035813 regulation of renal sodium excretion 2.641037e-4
GO:0045764 positive regulation of cellular amino acid metabolic process 2.663606e-4
GO:0042424 catecholamine catabolic process 2.928175e-4
GO:0043086 negative regulation of catalytic activity 2.968811e-4
GO:0009629 response to gravity 3.000142e-4
GO:0032900 negative regulation of neurotrophin production 3.214921e-4
GO:0032244 positive regulation of nucleoside transport 3.214921e-4
GO:0048239 negative regulation of DNA recombination at telomere 3.259440e-4
GO:0006430 lysyl-tRNA aminoacylation 3.259440e-4
GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 3.259440e-4
GO:0032714 negative regulation of interleukin-5 production 3.263256e-4
GO:0090197 positive regulation of chemokine secretion 3.433582e-4
GO:0033194 response to hydroperoxide 3.435825e-4
GO:0060460 left lung morphogenesis 3.617040e-4
GO:0002331 pre-B cell allelic exclusion 3.646972e-4
GO:0030001 metal ion transport 3.676681e-4
GO:0051964 negative regulation of synapse assembly 3.710375e-4
GO:0060381 positive regulation of single-stranded telomeric DNA binding 3.791715e-4
GO:0046986 negative regulation of hemoglobin biosynthetic process 3.791715e-4
GO:0043538 regulation of actin phosphorylation 3.791715e-4
GO:0031161 phosphatidylinositol catabolic process 3.791715e-4
GO:0030194 positive regulation of blood coagulation 3.818006e-4
GO:0006312 mitotic recombination 3.829799e-4
GO:0071277 cellular response to calcium ion 4.031228e-4
GO:0042663 regulation of endodermal cell fate specification 4.113517e-4
GO:0051894 positive regulation of focal adhesion assembly 4.537214e-4
GO:0043269 regulation of ion transport 4.579499e-4
GO:0006691 leukotriene metabolic process 4.628407e-4
GO:0030817 regulation of cAMP biosynthetic process 4.729049e-4
GO:0032101 regulation of response to external stimulus 4.750594e-4
GO:0050790 regulation of catalytic activity 4.802412e-4
GO:0001661 conditioned taste aversion 4.888908e-4
GO:0050820 positive regulation of coagulation 4.949597e-4
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 5.056881e-4
GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.086191e-4
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.086191e-4
GO:0034614 cellular response to reactive oxygen species 5.088453e-4
GO:0002251 organ or tissue specific immune response 5.482076e-4
GO:0032200 telomere organization 5.539587e-4
GO:0042697 menopause 5.820750e-4
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 5.965800e-4
GO:0042274 ribosomal small subunit biogenesis 5.984473e-4
GO:0000729 DNA double-strand break processing 6.183391e-4
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 6.211569e-4
GO:0060577 pulmonary vein morphogenesis 6.255568e-4
GO:0035964 COPI-coated vesicle budding 6.255568e-4
GO:0030802 regulation of cyclic nucleotide biosynthetic process 6.361754e-4
GO:0014049 positive regulation of glutamate secretion 6.592146e-4
GO:0010033 response to organic substance 6.716023e-4
GO:0071248 cellular response to metal ion 6.750662e-4
GO:0033628 regulation of cell adhesion mediated by integrin 6.861904e-4
GO:0032102 negative regulation of response to external stimulus 7.120967e-4
GO:0070198 protein localization to chromosome, telomeric region 7.298105e-4
GO:0014889 muscle atrophy 7.493399e-4
GO:0071241 cellular response to inorganic substance 7.747511e-4
GO:0034097 response to cytokine stimulus 7.879288e-4
GO:0055085 transmembrane transport 8.017456e-4
GO:0030033 microvillus assembly 8.024691e-4
GO:0003285 septum secundum development 8.024691e-4
GO:0003278 apoptosis involved in heart morphogenesis 8.072837e-4
GO:0007632 visual behavior 8.084899e-4
GO:0030490 maturation of SSU-rRNA 8.529130e-4
GO:0015844 monoamine transport 8.586625e-4
GO:0006820 anion transport 8.645234e-4
GO:0030517 negative regulation of axon extension 8.681152e-4
GO:0051928 positive regulation of calcium ion transport 8.933419e-4
GO:0060576 intestinal epithelial cell development 9.211383e-4
GO:0035553 oxidative single-stranded RNA demethylation 9.385779e-4
GO:0002720 positive regulation of cytokine production involved in immune response 9.432815e-4
GO:0008542 visual learning 9.689098e-4
GO:0001934 positive regulation of protein phosphorylation 9.795879e-4
GO:0051260 protein homooligomerization 9.811231e-4
GO:0034625 fatty acid elongation, monounsaturated fatty acid 9.901653e-4
GO:0050891 multicellular organismal water homeostasis 9.939124e-4
GO:0042048 olfactory behavior 1.001071e-3
GO:0001913 T cell mediated cytotoxicity 1.001071e-3
GO:0020027 hemoglobin metabolic process 1.007166e-3
GO:0031125 rRNA 3'-end processing 1.011508e-3
GO:0006508 proteolysis 1.017335e-3
GO:0015711 organic anion transport 1.108317e-3
GO:0071286 cellular response to magnesium ion 1.135098e-3
GO:0060206 estrous cycle phase 1.136267e-3
GO:0060837 blood vessel endothelial cell differentiation 1.152268e-3
GO:0015817 histidine transport 1.152268e-3
GO:0042420 dopamine catabolic process 1.152268e-3
GO:0001977 renal system process involved in regulation of blood volume 1.155350e-3
GO:0032782 bile acid secretion 1.256887e-3
GO:0072355 histone H3-T3 phosphorylation 1.256887e-3
GO:0010725 regulation of primitive erythrocyte differentiation 1.256887e-3
GO:0003096 renal sodium ion transport 1.256887e-3
GO:0019428 allantoin biosynthetic process 1.256887e-3
GO:0031081 nuclear pore distribution 1.277545e-3
GO:0001975 response to amphetamine 1.285017e-3
GO:0097070 ductus arteriosus closure 1.306736e-3
GO:0007202 activation of phospholipase C activity 1.344513e-3
GO:0050848 regulation of calcium-mediated signaling 1.356242e-3
GO:0019935 cyclic-nucleotide-mediated signaling 1.360083e-3
GO:0007212 dopamine receptor signaling pathway 1.370628e-3
GO:0031401 positive regulation of protein modification process 1.380338e-3
GO:0014048 regulation of glutamate secretion 1.383136e-3
GO:0035552 oxidative single-stranded DNA demethylation 1.393885e-3
GO:0006749 glutathione metabolic process 1.394772e-3
GO:0006955 immune response 1.420088e-3
GO:0043628 ncRNA 3'-end processing 1.438269e-3
GO:0046456 icosanoid biosynthetic process 1.450171e-3
GO:0030801 positive regulation of cyclic nucleotide metabolic process 1.461126e-3
GO:0045072 regulation of interferon-gamma biosynthetic process 1.475904e-3
GO:0000738 DNA catabolic process, exonucleolytic 1.501620e-3
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 1.503736e-3
GO:0045401 positive regulation of interleukin-3 biosynthetic process 1.503736e-3
GO:0032696 negative regulation of interleukin-13 production 1.539406e-3
GO:0043116 negative regulation of vascular permeability 1.566718e-3
GO:0071805 potassium ion transmembrane transport 1.568736e-3
GO:0006144 purine base metabolic process 1.572037e-3
GO:0006308 DNA catabolic process 1.589170e-3
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 1.591687e-3
GO:0048769 sarcomerogenesis 1.623843e-3
GO:0009443 pyridoxal 5'-phosphate salvage 1.623843e-3
GO:0035457 cellular response to interferon-alpha 1.625913e-3
GO:0016078 tRNA catabolic process 1.628552e-3
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction 1.628552e-3
GO:0003259 cardioblast anterior-lateral migration 1.628552e-3
GO:0060975 cardioblast migration to the midline involved in heart field formation 1.628552e-3
GO:0001682 tRNA 5'-leader removal 1.628552e-3
GO:0003210 cardiac atrium formation 1.628552e-3
GO:0003236 sinus venosus morphogenesis 1.628552e-3
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent 1.640438e-3
GO:0050746 regulation of lipoprotein metabolic process 1.691127e-3
GO:0090305 nucleic acid phosphodiester bond hydrolysis 1.705881e-3
GO:0033058 directional locomotion 1.716245e-3
GO:2000021 regulation of ion homeostasis 1.719313e-3
GO:0045777 positive regulation of blood pressure 1.756887e-3
GO:0030216 keratinocyte differentiation 1.875766e-3
GO:0007166 cell surface receptor linked signaling pathway 1.905271e-3
GO:0035621 ER to Golgi ceramide transport 2.010227e-3
GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process 2.010227e-3
GO:0033159 negative regulation of protein import into nucleus, translocation 2.023879e-3
GO:0045937 positive regulation of phosphate metabolic process 2.035216e-3
GO:0043501 skeletal muscle adaptation 2.093209e-3
GO:0002385 mucosal immune response 2.118099e-3
GO:0008643 carbohydrate transport 2.132843e-3
GO:0050850 positive regulation of calcium-mediated signaling 2.144133e-3
GO:0006833 water transport 2.160637e-3
GO:0034370 triglyceride-rich lipoprotein particle remodeling 2.165367e-3
GO:0010518 positive regulation of phospholipase activity 2.174629e-3
GO:0071705 nitrogen compound transport 2.194593e-3
GO:0050771 negative regulation of axonogenesis 2.217076e-3
GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 2.228435e-3
GO:0006867 asparagine transport 2.228435e-3
GO:0072376 protein activation cascade 2.230412e-3
GO:2000249 regulation of actin cytoskeleton reorganization 2.243515e-3
GO:0010959 regulation of metal ion transport 2.247032e-3
GO:0010876 lipid localization 2.290742e-3
GO:0065008 regulation of biological quality 2.291342e-3
GO:0002118 aggressive behavior 2.303592e-3
GO:0006111 regulation of gluconeogenesis 2.325719e-3
GO:0007160 cell-matrix adhesion 2.337164e-3
GO:0003018 vascular process in circulatory system 2.365254e-3
GO:0009628 response to abiotic stimulus 2.385681e-3
GO:0003209 cardiac atrium morphogenesis 2.410935e-3
GO:0000723 telomere maintenance 2.411802e-3
GO:0006956 complement activation 2.439723e-3
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 2.456846e-3
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 2.476460e-3
GO:0051915 induction of synaptic plasticity by chemical substance 2.481411e-3
GO:0007625 grooming behavior 2.498002e-3
GO:0060907 positive regulation of macrophage cytokine production 2.511963e-3
GO:0002639 positive regulation of immunoglobulin production 2.524571e-3
GO:0032268 regulation of cellular protein metabolic process 2.540831e-3
GO:0071816 tail-anchored membrane protein insertion into ER membrane 2.545499e-3
GO:0032210 regulation of telomere maintenance via telomerase 2.545499e-3
GO:0031440 regulation of mRNA 3'-end processing 2.572843e-3
GO:0031848 protection from non-homologous end joining at telomere 2.577363e-3
GO:0032202 telomere assembly 2.577363e-3
GO:0006407 rRNA export from nucleus 2.577363e-3
GO:0006438 valyl-tRNA aminoacylation 2.577363e-3
GO:0002069 columnar/cuboidal epithelial cell maturation 2.577363e-3
GO:0006636 unsaturated fatty acid biosynthetic process 2.662021e-3
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.669751e-3
GO:0032844 regulation of homeostatic process 2.681090e-3
GO:0045672 positive regulation of osteoclast differentiation 2.714800e-3
GO:0052547 regulation of peptidase activity 2.735504e-3
GO:0009415 response to water 2.779043e-3
GO:0071345 cellular response to cytokine stimulus 2.782961e-3
GO:0008635 activation of caspase activity by cytochrome c 2.827131e-3
GO:0021542 dentate gyrus development 2.863503e-3
GO:0009635 response to herbicide 2.912111e-3
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis 3.087745e-3
GO:0051592 response to calcium ion 3.094735e-3
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 3.127678e-3
GO:0051025 negative regulation of immunoglobulin secretion 3.127678e-3
GO:0031915 positive regulation of synaptic plasticity 3.156029e-3
GO:0002252 immune effector process 3.157069e-3
GO:0043631 RNA polyadenylation 3.174832e-3
GO:0071221 cellular response to bacterial lipopeptide 3.186533e-3
GO:0007631 feeding behavior 3.296507e-3
GO:0010517 regulation of phospholipase activity 3.336690e-3
GO:0042044 fluid transport 3.344151e-3
GO:0007029 endoplasmic reticulum organization 3.371700e-3
GO:0006750 glutathione biosynthetic process 3.388140e-3
GO:0034372 very-low-density lipoprotein particle remodeling 3.411682e-3
GO:0070245 positive regulation of thymocyte apoptosis 3.422368e-3
GO:0070344 regulation of fat cell proliferation 3.431974e-3
GO:0002227 innate immune response in mucosa 3.431974e-3
GO:0097006 regulation of plasma lipoprotein particle levels 3.433021e-3
GO:0071875 adrenergic receptor signaling pathway 3.433435e-3
GO:0048016 inositol phosphate-mediated signaling 3.446765e-3
GO:0050818 regulation of coagulation 3.486510e-3
GO:0070350 regulation of white fat cell proliferation 3.495430e-3
GO:0010565 regulation of cellular ketone metabolic process 3.498590e-3
GO:0006869 lipid transport 3.514336e-3
GO:0048266 behavioral response to pain 3.540823e-3
GO:0009191 ribonucleoside diphosphate catabolic process 3.544919e-3
GO:0043402 glucocorticoid mediated signaling pathway 3.567120e-3
GO:0002532 production of molecular mediator involved in inflammatory response 3.578427e-3
GO:0000186 activation of MAPKK activity 3.724018e-3
GO:0010832 negative regulation of myotube differentiation 3.729015e-3
GO:0051900 regulation of mitochondrial depolarization 3.744129e-3
GO:0048265 response to pain 3.809219e-3
GO:0031295 T cell costimulation 3.916358e-3
GO:0070328 triglyceride homeostasis 3.937384e-3
GO:0060191 regulation of lipase activity 3.937842e-3
GO:0002475 antigen processing and presentation via MHC class Ib 3.965099e-3
GO:0051541 elastin metabolic process 3.965099e-3
GO:0043316 cytotoxic T cell degranulation 3.989333e-3
GO:0019307 mannose biosynthetic process 3.989333e-3
GO:0000917 barrier septum formation 3.989333e-3
GO:0002826 negative regulation of T-helper 1 type immune response 3.989333e-3
GO:0051583 dopamine uptake 3.990520e-3
GO:0009185 ribonucleoside diphosphate metabolic process 4.008061e-3
GO:0042574 retinal metabolic process 4.016988e-3
GO:0042770 signal transduction in response to DNA damage 4.025573e-3
GO:0009620 response to fungus 4.028535e-3
GO:0040007 growth 4.056481e-3
GO:0045654 positive regulation of megakaryocyte differentiation 4.081731e-3
GO:0043056 forward locomotion 4.158882e-3
GO:0046881 positive regulation of follicle-stimulating hormone secretion 4.186734e-3
GO:0042245 RNA repair 4.186734e-3
GO:0009913 epidermal cell differentiation 4.230154e-3
GO:0002682 regulation of immune system process 4.276719e-3
GO:0050715 positive regulation of cytokine secretion 4.284617e-3
GO:0044243 multicellular organismal catabolic process 4.302847e-3
GO:0030421 defecation 4.342059e-3
GO:0070845 polyubiquitinated misfolded protein transport 4.342059e-3
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 4.342059e-3
GO:2000304 positive regulation of ceramide biosynthetic process 4.363185e-3
GO:0035814 negative regulation of renal sodium excretion 4.364390e-3
GO:0051788 response to misfolded protein 4.395055e-3
GO:0050996 positive regulation of lipid catabolic process 4.458382e-3
GO:0009190 cyclic nucleotide biosynthetic process 4.489634e-3
GO:0034220 ion transmembrane transport 4.496894e-3
GO:0030239 myofibril assembly 4.500728e-3
GO:0055014 atrial cardiac muscle cell development 4.532976e-3
GO:0006171 cAMP biosynthetic process 4.556941e-3
GO:0001504 neurotransmitter uptake 4.556941e-3
GO:0006811 ion transport 4.594181e-3
GO:0060710 chorio-allantoic fusion 4.595923e-3
GO:0010898 positive regulation of triglyceride catabolic process 4.602928e-3
GO:0051029 rRNA transport 4.621029e-3
GO:0035455 response to interferon-alpha 4.621029e-3
GO:0032205 negative regulation of telomere maintenance 4.621029e-3
GO:0042255 ribosome assembly 4.678244e-3
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 4.679755e-3
GO:0051336 regulation of hydrolase activity 4.685364e-3
GO:0014034 neural crest cell fate commitment 4.716900e-3
GO:0006307 DNA dealkylation involved in DNA repair 4.722221e-3
GO:0032689 negative regulation of interferon-gamma production 4.724733e-3
GO:0035750 protein localization to myelin sheath abaxonal region 4.752002e-3
GO:2000781 positive regulation of double-strand break repair 4.752002e-3
GO:0034241 positive regulation of macrophage fusion 4.752002e-3
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway 4.752002e-3
GO:0015966 diadenosine tetraphosphate biosynthetic process 4.752002e-3
GO:0031468 nuclear envelope reassembly 4.752002e-3
GO:0010996 response to auditory stimulus 4.752002e-3
GO:0060644 mammary gland epithelial cell differentiation 4.833144e-3
GO:0007214 gamma-aminobutyric acid signaling pathway 4.888154e-3
GO:0003091 renal water homeostasis 4.894761e-3
GO:0001570 vasculogenesis 4.957340e-3
GO:0009636 response to toxin 5.005177e-3
GO:0002253 activation of immune response 5.007391e-3
GO:0051246 regulation of protein metabolic process 5.034663e-3
GO:0015840 urea transport 5.108453e-3
GO:0002309 T cell proliferation involved in immune response 5.108453e-3
GO:0045987 positive regulation of smooth muscle contraction 5.112302e-3
GO:0006106 fumarate metabolic process 5.114658e-3
GO:0051937 catecholamine transport 5.147878e-3
GO:0010863 positive regulation of phospholipase C activity 5.207767e-3
GO:0035510 DNA dealkylation 5.259834e-3
GO:0033240 positive regulation of cellular amine metabolic process 5.259834e-3
GO:0051856 adhesion to symbiont 5.315423e-3
GO:0052572 response to host immune response 5.382014e-3
GO:0042402 cellular biogenic amine catabolic process 5.456545e-3
GO:0042110 T cell activation 5.457381e-3
GO:0007199 G-protein signaling, coupled to cGMP nucleotide second messenger 5.458541e-3
GO:0043001 Golgi to plasma membrane protein transport 5.468297e-3
GO:0030819 positive regulation of cAMP biosynthetic process 5.506674e-3
GO:0051549 positive regulation of keratinocyte migration 5.542484e-3
GO:0051180 vitamin transport 5.648370e-3
GO:0007618 mating 5.675197e-3
GO:0000070 mitotic sister chromatid segregation 5.675197e-3
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 5.717811e-3
GO:0061162 establishment of monopolar cell polarity 5.748863e-3
GO:0051917 regulation of fibrinolysis 5.840365e-3
GO:0032713 negative regulation of interleukin-4 production 5.840365e-3
GO:0022607 cellular component assembly 5.923237e-3
GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis 5.926576e-3
GO:0048841 regulation of axon extension involved in axon guidance 5.927891e-3
GO:0007016 cytoskeletal anchoring at plasma membrane 6.065658e-3
GO:0006518 peptide metabolic process 6.093876e-3
GO:0002709 regulation of T cell mediated immunity 6.197134e-3
GO:0030382 sperm mitochondrion organization 6.308646e-3
GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway 6.326040e-3
GO:0034765 regulation of ion transmembrane transport 6.353064e-3
GO:0032892 positive regulation of organic acid transport 6.388014e-3
GO:0043500 muscle adaptation 6.456099e-3
GO:0050877 neurological system process 6.490465e-3
GO:0046960 sensitization 6.492091e-3
GO:0042664 negative regulation of endodermal cell fate specification 6.492091e-3
GO:0071827 plasma lipoprotein particle organization 6.492166e-3
GO:0009725 response to hormone stimulus 6.510453e-3
GO:0050728 negative regulation of inflammatory response 6.662571e-3
GO:0030193 regulation of blood coagulation 6.756403e-3
GO:0070535 histone H2A K63-linked ubiquitination 6.815441e-3
GO:0021881 Wnt receptor signaling pathway involved in forebrain neuron fate commitment 6.815441e-3
GO:0015850 organic alcohol transport 6.819049e-3
GO:0008617 guanosine metabolic process 6.826729e-3
GO:0043154 negative regulation of caspase activity 6.827012e-3
GO:0006140 regulation of nucleotide metabolic process 6.906669e-3
GO:0051262 protein tetramerization 6.908870e-3
GO:0045078 positive regulation of interferon-gamma biosynthetic process 6.972500e-3
GO:0070234 positive regulation of T cell apoptosis 6.992862e-3
GO:0031032 actomyosin structure organization 7.102826e-3
GO:0060973 cell migration involved in heart development 7.131999e-3
GO:0042730 fibrinolysis 7.131999e-3
GO:0042339 keratan sulfate metabolic process 7.151992e-3
GO:2000334 positive regulation of blood microparticle formation 7.151992e-3
GO:0007172 signal complex assembly 7.151992e-3
GO:0032235 negative regulation of calcium ion transport via store-operated calcium channel activity 7.153085e-3
GO:0051257 spindle midzone assembly involved in meiosis 7.167376e-3
GO:0015959 diadenosine polyphosphate metabolic process 7.167376e-3
GO:0002768 immune response-regulating cell surface receptor signaling pathway 7.174598e-3
GO:0007190 activation of adenylate cyclase activity 7.178775e-3
GO:0030855 epithelial cell differentiation 7.183394e-3
GO:0009134 nucleoside diphosphate catabolic process 7.351583e-3
GO:0043085 positive regulation of catalytic activity 7.384431e-3
GO:0007320 insemination 7.417963e-3
GO:0001954 positive regulation of cell-matrix adhesion 7.426335e-3
GO:0050829 defense response to Gram-negative bacterium 7.457986e-3
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 7.459265e-3
GO:0019098 reproductive behavior 7.469267e-3
GO:0002329 pre-B cell differentiation 7.560819e-3
GO:0065005 protein-lipid complex assembly 7.631688e-3
GO:0043503 skeletal muscle fiber adaptation 7.644525e-3
GO:0050727 regulation of inflammatory response 7.658845e-3
GO:0010634 positive regulation of epithelial cell migration 7.689038e-3
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 7.700538e-3
GO:0070207 protein homotrimerization 7.700538e-3
GO:0006826 iron ion transport 7.752787e-3
GO:0048002 antigen processing and presentation of peptide antigen 7.769036e-3
GO:0035270 endocrine system development 7.828198e-3
GO:0070243 regulation of thymocyte apoptosis 7.877828e-3
GO:0044093 positive regulation of molecular function 7.896641e-3
GO:0035690 cellular response to drug 7.902046e-3
GO:0031124 mRNA 3'-end processing 7.940927e-3
GO:0006914 autophagy 7.976006e-3
GO:0002455 humoral immune response mediated by circulating immunoglobulin 8.005055e-3
GO:0061042 vascular wound healing 8.089664e-3
GO:0031275 regulation of lateral pseudopodium assembly 8.089664e-3
GO:0018960 4-nitrophenol metabolic process 8.089664e-3
GO:0019413 acetate biosynthetic process 8.089664e-3
GO:0019542 propionate biosynthetic process 8.089664e-3
GO:0000819 sister chromatid segregation 8.089995e-3
GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib 8.136352e-3
GO:0043558 regulation of translational initiation in response to stress 8.136352e-3
GO:0006282 regulation of DNA repair 8.166483e-3
GO:0048640 negative regulation of developmental growth 8.176679e-3
GO:0021502 neural fold elevation formation 8.190345e-3
GO:0090026 positive regulation of monocyte chemotaxis 8.202684e-3
GO:0009113 purine base biosynthetic process 8.202684e-3
GO:0046165 alcohol biosynthetic process 8.275483e-3
GO:0030804 positive regulation of cyclic nucleotide biosynthetic process 8.304336e-3
GO:0070925 organelle assembly 8.400436e-3
GO:0007620 copulation 8.519820e-3