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Novel motif:73

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name:motif73_GAGCKMGC

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0070979 protein K11-linked ubiquitination 6.345273e-11
GO:0021986 habenula development 2.332810e-10
GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation 2.938157e-8
GO:0044314 protein K27-linked ubiquitination 1.066408e-7
GO:0006281 DNA repair 1.316367e-7
GO:0071542 dopaminergic neuron differentiation 1.803624e-7
GO:0000079 regulation of cyclin-dependent protein kinase activity 1.930819e-7
GO:0006353 transcription termination, DNA-dependent 1.969918e-7
GO:0006369 termination of RNA polymerase II transcription 2.518184e-7
GO:0030421 defecation 3.099203e-7
GO:0006379 mRNA cleavage 3.827531e-7
GO:0035519 protein K29-linked ubiquitination 4.036700e-7
GO:0006270 DNA-dependent DNA replication initiation 2.303536e-6
GO:0045218 zonula adherens maintenance 3.125050e-6
GO:0046500 S-adenosylmethionine metabolic process 3.219555e-6
GO:0034551 mitochondrial respiratory chain complex III assembly 3.855487e-6
GO:0085020 protein K6-linked ubiquitination 5.767724e-6
GO:0006268 DNA unwinding involved in replication 6.004763e-6
GO:0021903 rostrocaudal neural tube patterning 6.439973e-6
GO:0003310 pancreatic A cell differentiation 8.153363e-6
GO:0000389 nuclear mRNA 3'-splice site recognition 9.039175e-6
GO:0006285 base-excision repair, AP site formation 9.039175e-6
GO:0031848 protection from non-homologous end joining at telomere 1.277487e-5
GO:0016233 telomere capping 1.487323e-5
GO:0018277 protein deamination 1.567240e-5
GO:0060976 coronary vasculature development 1.812539e-5
GO:0010982 regulation of high-density lipoprotein particle clearance 2.212381e-5
GO:0006298 mismatch repair 2.278150e-5
GO:0035470 positive regulation of vascular wound healing 2.293844e-5
GO:0002069 columnar/cuboidal epithelial cell maturation 2.389759e-5
GO:0050434 positive regulation of viral transcription 4.118053e-5
GO:0021892 cerebral cortex GABAergic interneuron differentiation 4.722567e-5
GO:0003329 pancreatic PP cell fate commitment 5.144961e-5
GO:0003326 pancreatic A cell fate commitment 5.144961e-5
GO:0008272 sulfate transport 5.952302e-5
GO:0043181 vacuolar sequestering 6.144346e-5
GO:0005985 sucrose metabolic process 6.144346e-5
GO:0000023 maltose metabolic process 6.144346e-5
GO:0010983 positive regulation of high-density lipoprotein particle clearance 6.744008e-5
GO:0035567 non-canonical Wnt receptor signaling pathway 7.484588e-5
GO:0090305 nucleic acid phosphodiester bond hydrolysis 7.991316e-5
GO:0046950 cellular ketone body metabolic process 8.080016e-5
GO:0045007 depurination 8.570386e-5
GO:0018993 somatic sex determination 8.790842e-5
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 1.231825e-4
GO:2000573 positive regulation of DNA biosynthetic process 1.317749e-4
GO:0010986 positive regulation of lipoprotein particle clearance 1.494201e-4
GO:0046168 glycerol-3-phosphate catabolic process 1.597714e-4
GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation 1.682428e-4
GO:0061032 visceral serous pericardium development 1.682428e-4
GO:0046984 regulation of hemoglobin biosynthetic process 1.682428e-4
GO:0070534 protein K63-linked ubiquitination 1.688186e-4
GO:0031047 gene silencing by RNA 1.800175e-4
GO:0090102 cochlea development 1.815471e-4
GO:0009264 deoxyribonucleotide catabolic process 1.888373e-4
GO:0050775 positive regulation of dendrite morphogenesis 1.898545e-4
GO:0048814 regulation of dendrite morphogenesis 1.914168e-4
GO:0031468 nuclear envelope reassembly 2.028430e-4
GO:0000160 two-component signal transduction system (phosphorelay) 2.207630e-4
GO:0022601 menstrual cycle phase 2.210105e-4
GO:0043503 skeletal muscle fiber adaptation 2.220249e-4
GO:0060338 regulation of type I interferon-mediated signaling pathway 2.316357e-4
GO:0000387 spliceosomal snRNP assembly 2.452481e-4
GO:0046782 regulation of viral transcription 2.517577e-4
GO:0032508 DNA duplex unwinding 2.784949e-4
GO:0051096 positive regulation of helicase activity 3.316292e-4
GO:0031860 telomeric 3' overhang formation 3.340913e-4
GO:0015816 glycine transport 3.680797e-4
GO:0050703 interleukin-1 alpha secretion 3.931196e-4
GO:0021530 spinal cord oligodendrocyte cell fate specification 4.329311e-4
GO:0010833 telomere maintenance via telomere lengthening 4.477565e-4
GO:2000016 negative regulation of determination of dorsal identity 4.681063e-4
GO:0046985 positive regulation of hemoglobin biosynthetic process 4.681063e-4
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 4.681063e-4
GO:0043973 histone H3-K4 acetylation 4.681063e-4
GO:0021532 neural tube patterning 4.683817e-4
GO:0043576 regulation of respiratory gaseous exchange 4.694868e-4
GO:0030579 ubiquitin-dependent SMAD protein catabolic process 4.719429e-4
GO:0090307 spindle assembly involved in mitosis 4.936058e-4
GO:0002074 extraocular skeletal muscle development 5.015368e-4
GO:0033600 negative regulation of mammary gland epithelial cell proliferation 5.094131e-4
GO:0042416 dopamine biosynthetic process 5.265229e-4
GO:0018364 peptidyl-glutamine methylation 5.417506e-4
GO:0071423 malate transmembrane transport 5.417506e-4
GO:0048291 isotype switching to IgG isotypes 5.417506e-4
GO:0006844 acyl carnitine transport 5.417506e-4
GO:0015709 thiosulfate transport 5.417506e-4
GO:0002368 B cell cytokine production 5.417506e-4
GO:0002842 positive regulation of T cell mediated immune response to tumor cell 5.417506e-4
GO:0006481 C-terminal protein methylation 5.501351e-4
GO:0007288 sperm axoneme assembly 5.521984e-4
GO:0046621 negative regulation of organ growth 5.713333e-4
GO:0010477 response to sulfur dioxide 5.982769e-4
GO:0002457 T cell antigen processing and presentation 5.982769e-4
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 6.043774e-4
GO:0010984 regulation of lipoprotein particle clearance 6.256059e-4
GO:0006646 phosphatidylethanolamine biosynthetic process 6.256059e-4
GO:0072203 cell proliferation involved in metanephros development 6.732926e-4
GO:0009451 RNA modification 7.119727e-4
GO:0060580 ventral spinal cord interneuron fate determination 7.138708e-4
GO:0003327 type B pancreatic cell fate commitment 7.138708e-4
GO:0045737 positive regulation of cyclin-dependent protein kinase activity 7.179689e-4
GO:0006308 DNA catabolic process 7.371082e-4
GO:0090085 regulation of protein deubiquitination 7.757837e-4
GO:0048561 establishment of organ orientation 8.108902e-4
GO:0030237 female sex determination 8.312570e-4
GO:0048102 autophagic cell death 8.619522e-4
GO:0060028 convergent extension involved in axis elongation 8.671902e-4
GO:0033299 secretion of lysosomal enzymes 8.671902e-4
GO:0033084 regulation of immature T cell proliferation in thymus 8.684142e-4
GO:0001510 RNA methylation 8.878560e-4
GO:0031507 heterochromatin formation 8.953524e-4
GO:0048239 negative regulation of DNA recombination at telomere 9.249487e-4
GO:0007206 activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway 9.249487e-4
GO:0045750 positive regulation of S phase of mitotic cell cycle 9.651504e-4
GO:0032392 DNA geometric change 9.683230e-4
GO:0009912 auditory receptor cell fate commitment 9.798618e-4
GO:0000731 DNA synthesis involved in DNA repair 1.003904e-3
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 1.022169e-3
GO:0021979 hypothalamus cell differentiation 1.022169e-3
GO:0060236 regulation of mitotic spindle organization 1.022169e-3
GO:0015827 tryptophan transport 1.022624e-3
GO:0021895 cerebral cortex neuron differentiation 1.045030e-3
GO:0043923 positive regulation by host of viral transcription 1.104481e-3
GO:0006398 histone mRNA 3'-end processing 1.180952e-3
GO:0071394 cellular response to testosterone stimulus 1.195933e-3
GO:0060576 intestinal epithelial cell development 1.239374e-3
GO:0046951 ketone body biosynthetic process 1.261746e-3
GO:0042637 catagen 1.261746e-3
GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation 1.268345e-3
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway 1.268345e-3
GO:0060248 detection of cell density by contact stimulus involved in contact inhibition 1.268345e-3
GO:0007371 ventral midline determination 1.268345e-3
GO:0010509 polyamine homeostasis 1.268345e-3
GO:0042696 menarche 1.348234e-3
GO:0034470 ncRNA processing 1.384645e-3
GO:0006382 adenosine to inosine editing 1.396748e-3
GO:0007100 mitotic centrosome separation 1.488003e-3
GO:0070079 histone H4-R3 demethylation 1.541759e-3
GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 1.541759e-3
GO:0070078 histone H3-R2 demethylation 1.541759e-3
GO:0060318 definitive erythrocyte differentiation 1.542802e-3
GO:0034447 very-low-density lipoprotein particle clearance 1.567691e-3
GO:0009789 positive regulation of abscisic acid mediated signaling pathway 1.567691e-3
GO:0033119 negative regulation of RNA splicing 1.567776e-3
GO:0032211 negative regulation of telomere maintenance via telomerase 1.592275e-3
GO:0060574 intestinal epithelial cell maturation 1.594229e-3
GO:0008057 eye pigment granule organization 1.594229e-3
GO:0030262 apoptotic nuclear change 1.625259e-3
GO:0009394 2'-deoxyribonucleotide metabolic process 1.634113e-3
GO:0006354 transcription elongation, DNA-dependent 1.675446e-3
GO:0007090 regulation of S phase of mitotic cell cycle 1.750415e-3
GO:0061001 regulation of dendritic spine morphogenesis 1.768190e-3
GO:0021985 neurohypophysis development 1.780389e-3
GO:0042747 circadian sleep/wake cycle, REM sleep 1.810635e-3
GO:0070179 D-serine biosynthetic process 1.810635e-3
GO:0031619 homologous chromosome orientation involved in meiotic metaphase I plate congression 1.810635e-3
GO:0070831 basement membrane assembly 1.878678e-3
GO:0009223 pyrimidine deoxyribonucleotide catabolic process 1.938095e-3
GO:0001946 lymphangiogenesis 1.958775e-3
GO:0030488 tRNA methylation 1.979229e-3
GO:0090103 cochlea morphogenesis 2.036881e-3
GO:0046709 IDP catabolic process 2.037240e-3
GO:0046032 ADP catabolic process 2.037240e-3
GO:0060730 regulation of intestinal epithelial structure maintenance 2.044643e-3
GO:0006244 pyrimidine nucleotide catabolic process 2.044643e-3
GO:0001975 response to amphetamine 2.282483e-3
GO:0008635 activation of caspase activity by cytochrome c 2.352286e-3
GO:0009155 purine deoxyribonucleotide catabolic process 2.364290e-3
GO:0030238 male sex determination 2.454850e-3
GO:0030917 midbrain-hindbrain boundary development 2.469988e-3
GO:0090179 planar cell polarity pathway involved in neural tube closure 2.482594e-3
GO:0042254 ribosome biogenesis 2.503894e-3
GO:0007216 metabotropic glutamate receptor signaling pathway 2.550351e-3
GO:0009219 pyrimidine deoxyribonucleotide metabolic process 2.590620e-3
GO:0061360 optic chiasma development 2.621314e-3
GO:2000597 positive regulation of optic nerve formation 2.621314e-3
GO:0035799 ureter maturation 2.621314e-3
GO:0021650 vestibulocochlear nerve formation 2.621314e-3
GO:0021633 optic nerve structural organization 2.621314e-3
GO:0033083 regulation of immature T cell proliferation 2.649115e-3
GO:0009262 deoxyribonucleotide metabolic process 2.663383e-3
GO:0042703 menstruation 2.693588e-3
GO:0019101 female somatic sex determination 2.693588e-3
GO:0017004 cytochrome complex assembly 2.693588e-3
GO:0003406 retinal pigment epithelium development 2.693588e-3
GO:0001522 pseudouridine synthesis 2.745139e-3
GO:0010498 proteasomal protein catabolic process 2.999821e-3
GO:0006368 transcription elongation from RNA polymerase II promoter 3.048958e-3
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 3.117233e-3
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 3.165304e-3
GO:0001787 natural killer cell proliferation 3.191978e-3
GO:0046607 positive regulation of centrosome cycle 3.191978e-3
GO:0000375 RNA splicing, via transesterification reactions 3.193182e-3
GO:2000774 positive regulation of cellular senescence 3.233865e-3
GO:0035986 senescence-associated heterochromatin focus formation 3.233865e-3
GO:0000398 nuclear mRNA splicing, via spliceosome 3.238581e-3
GO:0051095 regulation of helicase activity 3.353247e-3
GO:0030828 positive regulation of cGMP biosynthetic process 3.380053e-3
GO:0046952 ketone body catabolic process 3.501884e-3
GO:0001830 trophectodermal cell fate commitment 3.585695e-3
GO:0019405 alditol catabolic process 3.585695e-3
GO:0006396 RNA processing 3.590450e-3
GO:0002066 columnar/cuboidal epithelial cell development 3.599127e-3
GO:0000725 recombinational repair 3.610991e-3
GO:0021759 globus pallidus development 3.700883e-3
GO:0009452 RNA capping 3.728342e-3
GO:0072086 specification of loop of Henle identity 3.867211e-3
GO:0014040 positive regulation of Schwann cell differentiation 3.867211e-3
GO:0006261 DNA-dependent DNA replication 3.872398e-3
GO:0060764 cell-cell signaling involved in mammary gland development 3.976116e-3
GO:0051984 positive regulation of chromosome segregation 3.976116e-3
GO:0006311 meiotic gene conversion 3.976116e-3
GO:0045128 negative regulation of reciprocal meiotic recombination 3.976116e-3
GO:0031442 positive regulation of mRNA 3'-end processing 4.098791e-3
GO:0072144 glomerular mesangial cell development 4.134439e-3
GO:0072011 glomerular endothelium development 4.134439e-3
GO:0009299 mRNA transcription 4.235299e-3
GO:0090342 regulation of cell aging 4.259544e-3
GO:0035195 gene silencing by miRNA 4.275492e-3
GO:0070194 synaptonemal complex disassembly 4.588756e-3
GO:0008216 spermidine metabolic process 4.588756e-3
GO:0031662 positive regulation of cyclin-dependent protein kinase activity involved in G2/M 4.588756e-3
GO:0019230 proprioception 4.603345e-3
GO:0090343 positive regulation of cell aging 4.650217e-3
GO:0002071 glandular epithelial cell maturation 4.689890e-3
GO:0071167 ribonucleoprotein complex import into nucleus 4.689890e-3
GO:0033590 response to cobalamin 4.729830e-3
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development 4.729830e-3
GO:0006117 acetaldehyde metabolic process 4.729830e-3
GO:0051089 constitutive protein ectodomain proteolysis 4.815076e-3
GO:0046604 positive regulation of mitotic centrosome separation 4.833011e-3
GO:0097039 protein linear polyubiquitination 4.848929e-3
GO:0060923 cardiac muscle cell fate commitment 4.848929e-3
GO:0006284 base-excision repair 4.916368e-3
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly 5.049648e-3
GO:0040015 negative regulation of multicellular organism growth 5.184658e-3
GO:0021819 layer formation in cerebral cortex 5.332033e-3
GO:0035725 sodium ion transmembrane transport 5.365117e-3
GO:0060334 regulation of interferon-gamma-mediated signaling pathway 5.390069e-3
GO:0032185 septin cytoskeleton organization 5.489148e-3
GO:0071166 ribonucleoprotein complex localization 5.493676e-3
GO:0035425 autocrine signaling 5.493676e-3
GO:0010835 regulation of protein ADP-ribosylation 5.493676e-3
GO:0035886 vascular smooth muscle cell differentiation 5.511995e-3
GO:0030644 cellular chloride ion homeostasis 5.516220e-3
GO:0061003 positive regulation of dendritic spine morphogenesis 5.525719e-3
GO:0042149 cellular response to glucose starvation 5.536920e-3
GO:0006482 protein demethylation 5.574306e-3
GO:0010989 negative regulation of low-density lipoprotein particle clearance 5.688324e-3
GO:0000724 double-strand break repair via homologous recombination 5.689084e-3
GO:0000722 telomere maintenance via recombination 5.783266e-3
GO:0007020 microtubule nucleation 5.796469e-3
GO:0060623 regulation of chromosome condensation 5.939614e-3
GO:0071283 cellular response to iron(III) ion 5.939614e-3
GO:0060371 regulation of atrial cardiomyocyte membrane depolarization 5.939614e-3
GO:0071469 cellular response to alkalinity 5.939614e-3
GO:0015761 mannose transport 5.939614e-3
GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 5.939614e-3
GO:0016078 tRNA catabolic process 5.939614e-3
GO:0001682 tRNA 5'-leader removal 5.939614e-3
GO:0046680 response to DDT 5.939614e-3
GO:0061101 neuroendocrine cell differentiation 6.056128e-3
GO:0032070 regulation of deoxyribonuclease activity 6.083838e-3
GO:0051355 proprioception involved in equilibrioception 6.120663e-3
GO:0046940 nucleoside monophosphate phosphorylation 6.120663e-3
GO:0015878 biotin transport 6.120663e-3
GO:0015887 pantothenate transmembrane transport 6.120663e-3
GO:0016598 protein arginylation 6.120663e-3
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 6.283993e-3
GO:0043921 modulation by host of viral transcription 6.385726e-3
GO:0022613 ribonucleoprotein complex biogenesis 6.419928e-3
GO:0006309 DNA fragmentation involved in apoptotic nuclear change 6.483944e-3
GO:0009186 deoxyribonucleoside diphosphate metabolic process 6.491558e-3
GO:0046939 nucleotide phosphorylation 6.586904e-3
GO:0051645 Golgi localization 6.595304e-3
GO:0015693 magnesium ion transport 6.635202e-3
GO:0048665 neuron fate specification 6.666847e-3
GO:0021555 midbrain-hindbrain boundary morphogenesis 6.828049e-3
GO:0000380 alternative nuclear mRNA splicing, via spliceosome 6.828049e-3
GO:0008535 respiratory chain complex IV assembly 6.912496e-3
GO:0045008 depyrimidination 6.913962e-3
GO:0060179 male mating behavior 6.957061e-3
GO:0045943 positive regulation of transcription from RNA polymerase I promoter 6.984844e-3
GO:0022616 DNA strand elongation 7.063306e-3
GO:0043967 histone H4 acetylation 7.169565e-3
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 7.536993e-3
GO:0060430 lung saccule development 7.541313e-3
GO:0035137 hindlimb morphogenesis 7.656987e-3
GO:0090002 establishment of protein localization in plasma membrane 7.787047e-3
GO:0007350 blastoderm segmentation 7.853137e-3
GO:0006540 glutamate decarboxylation to succinate 7.974347e-3
GO:0048013 ephrin receptor signaling pathway 8.096188e-3
GO:0006361 transcription initiation from RNA polymerase I promoter 8.150841e-3
GO:0018026 peptidyl-lysine monomethylation 8.192738e-3
GO:0090086 negative regulation of protein deubiquitination 8.366039e-3
GO:0045039 protein import into mitochondrial inner membrane 8.479547e-3
GO:0072166 posterior mesonephric tubule development 8.616230e-3
GO:0010460 positive regulation of heart rate 8.638493e-3
GO:0033057 multicellular organismal reproductive behavior 8.696211e-3
GO:0042668 auditory receptor cell fate determination 8.878284e-3
GO:0006538 glutamate catabolic process 8.878284e-3
GO:0032205 negative regulation of telomere maintenance 9.041992e-3
GO:0006556 S-adenosylmethionine biosynthetic process 9.042504e-3
GO:0019264 glycine biosynthetic process from serine 9.048540e-3
GO:0000921 septin ring assembly 9.048540e-3
GO:0033088 negative regulation of immature T cell proliferation in thymus 9.081862e-3
GO:0051013 microtubule severing 9.239635e-3
GO:0030823 regulation of cGMP metabolic process 9.646216e-3
GO:0090224 regulation of spindle organization 9.718270e-3
GO:0000244 assembly of spliceosomal tri-snRNP 9.718270e-3
GO:0060084 synaptic transmission involved in micturition 9.764122e-3
GO:0060520 activation of prostate induction by androgen receptor signaling pathway 9.764122e-3
GO:0050861 positive regulation of B cell receptor signaling pathway 9.764122e-3
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 9.764122e-3
GO:0030302 deoxynucleotide transport 9.764122e-3
GO:0019102 male somatic sex determination 9.764122e-3
GO:0031914 negative regulation of synaptic plasticity 9.764122e-3
GO:0045720 negative regulation of integrin biosynthetic process 9.764122e-3
GO:0070845 polyubiquitinated misfolded protein transport 9.948743e-3
GO:0051882 mitochondrial depolarization 1.027339e-2
GO:0021528 commissural neuron differentiation in spinal cord 1.027339e-2
GO:0045217 cell-cell junction maintenance 1.056399e-2
GO:0048524 positive regulation of viral reproduction 1.056973e-2
GO:2000119 negative regulation of sodium-dependent phosphate transport 1.074338e-2
GO:0034699 response to luteinizing hormone stimulus 1.074338e-2
GO:0001923 B-1 B cell differentiation 1.074338e-2
GO:0008295 spermidine biosynthetic process 1.074338e-2
GO:0046718 entry of virus into host cell 1.075457e-2
GO:0090136 epithelial cell-cell adhesion 1.077004e-2
GO:0070918 production of small RNA involved in gene silencing by RNA 1.087520e-2
GO:0051531 NFAT protein import into nucleus 1.094124e-2
GO:0070544 histone H3-K36 demethylation 1.115690e-2
GO:0060381 positive regulation of single-stranded telomeric DNA binding 1.116429e-2
GO:0006189 'de novo' IMP biosynthetic process 1.116429e-2
GO:0051318 G1 phase 1.123738e-2
GO:0018283 iron incorporation into metallo-sulfur cluster 1.147938e-2
GO:0010988 regulation of low-density lipoprotein particle clearance 1.147938e-2
GO:0045819 positive regulation of glycogen catabolic process 1.161595e-2
GO:0008595 anterior/posterior axis specification, embryo 1.164143e-2
GO:0000710 meiotic mismatch repair 1.168124e-2
GO:0034214 protein hexamerization 1.168124e-2
GO:0042069 regulation of catecholamine metabolic process 1.171120e-2
GO:0042473 outer ear morphogenesis 1.186466e-2
GO:0006473 protein acetylation 1.210325e-2
GO:0061103 carotid body glomus cell differentiation 1.229538e-2
GO:0061102 stomach neuroendocrine cell differentiation 1.229538e-2
GO:0061104 adrenal chromaffin cell differentiation 1.229538e-2
GO:0071259 cellular response to magnetism 1.229538e-2
GO:0060163 subpallium neuron fate commitment 1.229538e-2
GO:0003359 noradrenergic neuron fate commitment 1.229538e-2
GO:0061100 lung neuroendocrine cell differentiation 1.229538e-2
GO:0007400 neuroblast fate determination 1.229538e-2
GO:0060165 regulation of timing of subpallium neuron differentiation 1.229538e-2
GO:0060711 labyrinthine layer development 1.236020e-2
GO:0006098 pentose-phosphate shunt 1.236394e-2
GO:0006406 mRNA export from nucleus 1.250565e-2
GO:0009070 serine family amino acid biosynthetic process 1.269268e-2
GO:0072125 negative regulation of glomerular mesangial cell proliferation 1.277995e-2
GO:2001037 positive regulation of tongue muscle cell differentiation 1.306991e-2
GO:0097152 mesenchymal cell apoptosis 1.306991e-2
GO:0034314 Arp2/3 complex-mediated actin nucleation 1.306991e-2
GO:0060982 coronary artery morphogenesis 1.306991e-2
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway 1.306991e-2
GO:0021997 neural plate axis specification 1.318572e-2
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 1.318572e-2
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 1.318572e-2
GO:0016556 mRNA modification 1.327580e-2
GO:0051898 negative regulation of protein kinase B signaling cascade 1.339752e-2
GO:0034660 ncRNA metabolic process 1.366900e-2
GO:2000974 negative regulation of pro-B cell differentiation 1.371338e-2
GO:0014028 notochord formation 1.386643e-2
GO:0007212 dopamine receptor signaling pathway 1.391854e-2
GO:2000195 negative regulation of female gonad development 1.415715e-2
GO:0035196 production of miRNAs involved in gene silencing by miRNA 1.417511e-2
GO:0006784 heme a biosynthetic process 1.431059e-2
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 1.431059e-2
GO:0006287 base-excision repair, gap-filling 1.436749e-2
GO:0060712 spongiotrophoblast layer development 1.437103e-2
GO:0030826 regulation of cGMP biosynthetic process 1.437406e-2
GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 1.471610e-2
GO:0060017 parathyroid gland development 1.487692e-2
GO:0071422 succinate transmembrane transport 1.493949e-2
GO:0046174 polyol catabolic process 1.493949e-2
GO:0044088 regulation of vacuole organization 1.493949e-2
GO:0060998 regulation of dendritic spine development 1.499019e-2
GO:0051088 PMA-inducible membrane protein ectodomain proteolysis 1.504851e-2
GO:0051005 negative regulation of lipoprotein lipase activity 1.551120e-2
GO:0008344 adult locomotory behavior 1.561920e-2
GO:0034393 positive regulation of smooth muscle cell apoptosis 1.579716e-2
GO:0061303 cornea development in camera-type eye 1.596365e-2
GO:0006260 DNA replication 1.609124e-2
GO:0046031 ADP metabolic process 1.610407e-2
GO:0071105 response to interleukin-11 1.626206e-2
GO:0045585 positive regulation of cytotoxic T cell differentiation 1.626206e-2
GO:0008049 male courtship behavior 1.626206e-2
GO:0035356 cellular triglyceride homeostasis 1.639871e-2
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 1.641238e-2
GO:0090303 positive regulation of wound healing 1.672025e-2
GO:2000194 regulation of female gonad development 1.692231e-2
GO:0043501 skeletal muscle adaptation 1.696401e-2
GO:0006271 DNA strand elongation involved in DNA replication 1.702603e-2
GO:0072111 cell proliferation involved in kidney development 1.702760e-2
GO:0016553 base conversion or substitution editing 1.750215e-2
GO:0009258 10-formyltetrahydrofolate catabolic process 1.750525e-2
GO:0009263 deoxyribonucleotide biosynthetic process 1.750711e-2
GO:0007004 telomere maintenance via telomerase 1.750711e-2
GO:0021586 pons maturation 1.755357e-2
GO:0002765 immune response-inhibiting signal transduction 1.755357e-2
GO:0043476 pigment accumulation 1.769899e-2
GO:0043482 cellular pigment accumulation 1.769899e-2
GO:0009648 photoperiodism 1.769899e-2
GO:0045047 protein targeting to ER 1.775900e-2
GO:0006370 mRNA capping 1.776719e-2
GO:0000578 embryonic axis specification 1.784092e-2
GO:0060421 positive regulation of heart growth 1.791034e-2
GO:2000111 positive regulation of macrophage apoptosis 1.801302e-2
GO:0030178 negative regulation of Wnt receptor signaling pathway 1.801795e-2
GO:0003148 outflow tract septum morphogenesis 1.802059e-2
GO:0016573 histone acetylation 1.806880e-2
GO:0003311 pancreatic D cell differentiation 1.827941e-2
GO:0090104 pancreatic E cell differentiation 1.827941e-2
GO:0002051 osteoblast fate commitment 1.831520e-2
GO:0072075 metanephric mesenchyme development 1.845834e-2
GO:0043543 protein acylation 1.859605e-2
GO:0006527 arginine catabolic process 1.864850e-2
GO:0048840 otolith development 1.868969e-2
GO:0035194 posttranscriptional gene silencing by RNA 1.873920e-2
GO:0000723 telomere maintenance 1.880942e-2
GO:0018352 protein-pyridoxal-5-phosphate linkage 1.887860e-2
GO:0019086 late viral mRNA transcription 1.887860e-2
GO:0060847 endothelial cell fate specification 1.900200e-2
GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway 1.900200e-2
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production 1.900200e-2
GO:0032077 positive regulation of deoxyribonuclease activity 1.900200e-2
GO:0032738 positive regulation of interleukin-15 production 1.900200e-2
GO:0032853 positive regulation of Ran GTPase activity 1.900200e-2
GO:0065002 intracellular protein transmembrane transport 1.906238e-2
GO:0070535 histone H2A K63-linked ubiquitination 1.908957e-2
GO:0035621 ER to Golgi ceramide transport 1.908957e-2
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 1.908957e-2
GO:0009589 detection of UV 1.908957e-2
GO:0010826 negative regulation of centrosome duplication 1.908957e-2
GO:0006363 termination of RNA polymerase I transcription 1.923787e-2
GO:0001982 baroreceptor response to decreased systemic arterial blood pressure 1.923846e-2
GO:0048343 paraxial mesodermal cell fate commitment 1.943102e-2
GO:0070885 negative regulation of calcineurin-NFAT signaling pathway 1.943102e-2
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 1.948346e-2
GO:0006545 glycine biosynthetic process 1.957848e-2
GO:0045662 negative regulation of myoblast differentiation 1.980760e-2
GO:0060253 negative regulation of glial cell proliferation 1.984114e-2
GO:0015789 UDP-N-acetylgalactosamine transport 2.005598e-2
GO:0035883 enteroendocrine cell differentiation 2.005598e-2
GO:0014816 satellite cell differentiation 2.005598e-2
GO:0015787 UDP-glucuronic acid transport 2.005598e-2
GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.005598e-2
GO:0043570 maintenance of DNA repeat elements 2.021621e-2
GO:0006171 cAMP biosynthetic process 2.080712e-2
GO:0050746 regulation of lipoprotein metabolic process 2.100950e-2
GO:0031293 membrane protein intracellular domain proteolysis 2.113982e-2
GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis 2.115729e-2
GO:0050773 regulation of dendrite development 2.129520e-2
GO:0051301 cell division 2.142706e-2
GO:0060014 granulosa cell differentiation 2.171627e-2
GO:0010987 negative regulation of high-density lipoprotein particle clearance 2.192849e-2
GO:0010897 negative regulation of triglyceride catabolic process 2.192849e-2
GO:0043414 macromolecule methylation 2.194828e-2
GO:0007379 segment specification 2.218179e-2
GO:0097084 vascular smooth muscle cell development 2.230167e-2
GO:0006351 transcription, DNA-dependent 2.268284e-2
GO:0045627 positive regulation of T-helper 1 cell differentiation 2.286458e-2
GO:0048664 neuron fate determination 2.286534e-2
GO:0033092 positive regulation of immature T cell proliferation in thymus 2.314988e-2
GO:0048210 Golgi vesicle fusion to target membrane 2.328385e-2
GO:0070814 hydrogen sulfide biosynthetic process 2.328385e-2
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 2.328385e-2
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 2.328385e-2
GO:0071104 response to interleukin-9 2.367051e-2
GO:0070715 sodium-dependent organic cation transport 2.390309e-2
GO:2000227 negative regulation of pancreatic A cell differentiation 2.390309e-2
GO:2000978 negative regulation of forebrain neuron differentiation 2.390309e-2
GO:0061106 negative regulation of stomach neuroendocrine cell differentiation 2.390309e-2
GO:0016082 synaptic vesicle priming 2.390309e-2
GO:0046331 lateral inhibition 2.390309e-2
GO:0052106 quorum sensing involved in interaction with host 2.390309e-2
GO:0060731 positive regulation of intestinal epithelial structure maintenance 2.390309e-2
GO:0043314 negative regulation of neutrophil degranulation 2.395057e-2
GO:0045299 otolith mineralization 2.422106e-2
GO:0043922 negative regulation by host of viral transcription 2.426335e-2
GO:0033058 directional locomotion 2.435100e-2
GO:0043313 regulation of neutrophil degranulation 2.465591e-2
GO:0045922 negative regulation of fatty acid metabolic process 2.468826e-2
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 2.503000e-2
GO:0001881 receptor recycling 2.515499e-2
GO:0070857 regulation of bile acid biosynthetic process 2.521943e-2
GO:0021562 vestibulocochlear nerve development 2.521943e-2
GO:0001842 neural fold formation 2.521943e-2
GO:0022007 convergent extension involved in neural plate elongation 2.527280e-2
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.527280e-2
GO:0070625 zymogen granule exocytosis 2.548674e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0010467 gene expression 6.093035e-11
GO:0090304 nucleic acid metabolic process 1.219455e-10
GO:0007076 mitotic chromosome condensation 5.142277e-9
GO:0044260 cellular macromolecule metabolic process 7.111381e-9
GO:0048285 organelle fission 9.666836e-9
GO:0051276 chromosome organization 1.202710e-8
GO:0007067 mitosis 1.355572e-8
GO:0000087 M phase of mitotic cell cycle 2.326951e-8
GO:0031507 heterochromatin formation 2.646355e-8
GO:0000279 M phase 3.425924e-8
GO:2000774 positive regulation of cellular senescence 4.082905e-8
GO:0090402 oncogene-induced senescence 4.082905e-8
GO:0035986 senescence-associated heterochromatin focus formation 4.082905e-8
GO:0016070 RNA metabolic process 4.239218e-8
GO:0016567 protein ubiquitination 4.384689e-8
GO:0061084 negative regulation of protein refolding 8.997480e-8
GO:0006139 nucleobase-containing compound metabolic process 1.153117e-7
GO:2000772 regulation of cellular senescence 1.197919e-7
GO:0048539 bone marrow development 1.319916e-7
GO:0034645 cellular macromolecule biosynthetic process 1.584024e-7
GO:0032446 protein modification by small protein conjugation 1.688768e-7
GO:0006351 transcription, DNA-dependent 1.716922e-7
GO:0006415 translational termination 1.938426e-7
GO:0032774 RNA biosynthetic process 2.213796e-7
GO:0006325 chromatin organization 2.633758e-7
GO:0045647 negative regulation of erythrocyte differentiation 2.757699e-7
GO:0018279 protein N-linked glycosylation via asparagine 2.835891e-7
GO:0022403 cell cycle phase 3.688927e-7
GO:0006297 nucleotide-excision repair, DNA gap filling 3.720027e-7
GO:0046985 positive regulation of hemoglobin biosynthetic process 4.124287e-7
GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery 4.124287e-7
GO:0043973 histone H3-K4 acetylation 4.124287e-7
GO:0009059 macromolecule biosynthetic process 7.724717e-7
GO:0051586 positive regulation of dopamine uptake 7.732936e-7
GO:0016226 iron-sulfur cluster assembly 1.310776e-6
GO:0000278 mitotic cell cycle 1.625625e-6
GO:0071103 DNA conformation change 2.044339e-6
GO:0006545 glycine biosynthetic process 2.233993e-6
GO:0060764 cell-cell signaling involved in mammary gland development 2.408109e-6
GO:0031129 inductive cell-cell signaling 2.408109e-6
GO:0046984 regulation of hemoglobin biosynthetic process 2.629836e-6
GO:0072044 collecting duct development 2.851994e-6
GO:0016568 chromatin modification 2.978149e-6
GO:0030902 hindbrain development 3.429311e-6
GO:0006323 DNA packaging 4.107307e-6
GO:0051168 nuclear export 6.723367e-6
GO:0051725 protein de-ADP-ribosylation 7.909417e-6
GO:0006405 RNA export from nucleus 8.379496e-6
GO:0030261 chromosome condensation 8.577018e-6
GO:0060319 primitive erythrocyte differentiation 9.781937e-6
GO:0010987 negative regulation of high-density lipoprotein particle clearance 1.170666e-5
GO:0010897 negative regulation of triglyceride catabolic process 1.170666e-5
GO:0071777 positive regulation of cell cycle cytokinesis 1.456386e-5
GO:0002052 positive regulation of neuroblast proliferation 2.150770e-5
GO:0021915 neural tube development 2.337140e-5
GO:0033566 gamma-tubulin complex localization 2.580869e-5
GO:0061034 olfactory bulb mitral cell layer development 2.608688e-5
GO:0051645 Golgi localization 2.727339e-5
GO:0072109 glomerular mesangium development 2.727339e-5
GO:0051301 cell division 2.745448e-5
GO:0050658 RNA transport 3.586096e-5
GO:0043248 proteasome assembly 3.598909e-5
GO:0043653 mitochondrial fragmentation involved in apoptosis 3.639319e-5
GO:0000819 sister chromatid segregation 3.957072e-5
GO:0000070 mitotic sister chromatid segregation 4.663258e-5
GO:0006487 protein N-linked glycosylation 5.489988e-5
GO:0045955 negative regulation of calcium ion-dependent exocytosis 5.628324e-5
GO:0018205 peptidyl-lysine modification 5.635542e-5
GO:0006403 RNA localization 6.756320e-5
GO:0006366 transcription from RNA polymerase II promoter 7.451800e-5
GO:0072111 cell proliferation involved in kidney development 7.819348e-5
GO:0071922 regulation of cohesin localization to chromatin 7.884772e-5
GO:0060482 lobar bronchus development 7.884772e-5
GO:0060242 contact inhibition 8.324446e-5
GO:0060005 vestibular reflex 8.350098e-5
GO:0071104 response to interleukin-9 8.356389e-5
GO:0015780 nucleotide-sugar transport 8.642344e-5
GO:0046882 negative regulation of follicle-stimulating hormone secretion 8.713502e-5
GO:2000381 negative regulation of mesoderm development 9.997030e-5
GO:0018192 enzyme active site formation via L-cysteine persulfide 1.153050e-4
GO:0016569 covalent chromatin modification 1.177110e-4
GO:0006412 translation 1.254489e-4
GO:0032467 positive regulation of cytokinesis 1.256322e-4
GO:0010994 free ubiquitin chain polymerization 1.335382e-4
GO:0060480 lung goblet cell differentiation 1.372068e-4
GO:0006409 tRNA export from nucleus 1.410292e-4
GO:0001843 neural tube closure 1.514583e-4
GO:0021549 cerebellum development 1.570920e-4
GO:0006493 protein O-linked glycosylation 1.739879e-4
GO:0060684 epithelial-mesenchymal cell signaling 1.883225e-4
GO:0006657 CDP-choline pathway 1.948625e-4
GO:0010982 regulation of high-density lipoprotein particle clearance 2.013106e-4
GO:0022402 cell cycle process 2.189147e-4
GO:0006188 IMP biosynthetic process 2.199189e-4
GO:0022037 metencephalon development 2.417959e-4
GO:0016075 rRNA catabolic process 2.494215e-4
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 2.680538e-4
GO:0046881 positive regulation of follicle-stimulating hormone secretion 2.765189e-4
GO:0030263 apoptotic chromosome condensation 2.765189e-4
GO:0016570 histone modification 2.799372e-4
GO:2000036 regulation of stem cell maintenance 2.936391e-4
GO:0032717 negative regulation of interleukin-8 production 3.087248e-4
GO:0006281 DNA repair 3.179682e-4
GO:0060606 tube closure 3.292568e-4
GO:0009082 branched chain family amino acid biosynthetic process 3.320020e-4
GO:0072303 positive regulation of glomerular metanephric mesangial cell proliferation 3.462666e-4
GO:0035269 protein O-linked mannosylation 3.462666e-4
GO:0006406 mRNA export from nucleus 3.646684e-4
GO:0033083 regulation of immature T cell proliferation 3.672496e-4
GO:0032057 negative regulation of translational initiation in response to stress 3.724332e-4
GO:2000384 negative regulation of ectoderm development 3.933316e-4
GO:0014020 primary neural tube formation 4.464261e-4
GO:0032007 negative regulation of TOR signaling cascade 4.647175e-4
GO:0032119 sequestering of zinc ion 4.710989e-4
GO:0060236 regulation of mitotic spindle organization 4.724392e-4
GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway 4.724392e-4
GO:0035573 N-terminal peptidyl-serine trimethylation 5.005372e-4
GO:0046604 positive regulation of mitotic centrosome separation 5.005372e-4
GO:0018012 N-terminal peptidyl-alanine trimethylation 5.005372e-4
GO:0035572 N-terminal peptidyl-serine dimethylation 5.005372e-4
GO:0021528 commissural neuron differentiation in spinal cord 5.005372e-4
GO:0018016 N-terminal peptidyl-proline dimethylation 5.005372e-4
GO:0050995 negative regulation of lipid catabolic process 5.091715e-4
GO:0034641 cellular nitrogen compound metabolic process 5.271864e-4
GO:0021532 neural tube patterning 5.360123e-4
GO:0016926 protein desumoylation 6.372471e-4
GO:0002175 protein localization to paranode region of axon 6.372471e-4
GO:0070647 protein modification by small protein conjugation or removal 6.595912e-4
GO:0006189 'de novo' IMP biosynthetic process 6.638698e-4
GO:0010960 magnesium ion homeostasis 6.638698e-4
GO:0006346 methylation-dependent chromatin silencing 7.096760e-4
GO:0019348 dolichol metabolic process 7.132377e-4
GO:0006398 histone mRNA 3'-end processing 7.132377e-4
GO:0002036 regulation of L-glutamate transport 7.132377e-4
GO:0031508 centromeric heterochromatin formation 7.717234e-4
GO:0009912 auditory receptor cell fate commitment 8.278103e-4
GO:0010725 regulation of primitive erythrocyte differentiation 8.500892e-4
GO:0042998 positive regulation of Golgi to plasma membrane protein transport 8.500892e-4
GO:0061088 regulation of sequestering of zinc ion 8.737437e-4
GO:0010157 response to chlorate 8.792459e-4
GO:0007059 chromosome segregation 9.147282e-4
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 9.726604e-4
GO:0016573 histone acetylation 9.738834e-4
GO:0072110 glomerular mesangial cell proliferation 1.012102e-3
GO:0033169 histone H3-K9 demethylation 1.021174e-3
GO:0070584 mitochondrion morphogenesis 1.022249e-3
GO:0043148 mitotic spindle stabilization 1.027934e-3
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 1.027934e-3
GO:0022417 protein maturation by protein folding 1.027934e-3
GO:0006354 transcription elongation, DNA-dependent 1.137951e-3
GO:0007049 cell cycle 1.183920e-3
GO:0070076 histone lysine demethylation 1.210342e-3
GO:0010870 positive regulation of receptor biosynthetic process 1.211985e-3
GO:0045625 regulation of T-helper 1 cell differentiation 1.213335e-3
GO:0048846 axon extension involved in axon guidance 1.223999e-3
GO:0072126 positive regulation of glomerular mesangial cell proliferation 1.230247e-3
GO:0071506 cellular response to mycophenolic acid 1.230247e-3
GO:0046015 regulation of transcription by glucose 1.280402e-3
GO:0071174 mitotic cell cycle spindle checkpoint 1.285805e-3
GO:0016540 protein autoprocessing 1.285805e-3
GO:0021853 cerebral cortex GABAergic interneuron migration 1.288908e-3
GO:0021757 caudate nucleus development 1.293315e-3
GO:0021758 putamen development 1.293315e-3
GO:0072017 distal tubule development 1.310044e-3
GO:0018394 peptidyl-lysine acetylation 1.316759e-3
GO:0060215 primitive hemopoiesis 1.429952e-3
GO:0001841 neural tube formation 1.447860e-3
GO:0070979 protein K11-linked ubiquitination 1.458949e-3
GO:0072093 metanephric renal vesicle formation 1.527578e-3
GO:0010989 negative regulation of low-density lipoprotein particle clearance 1.527578e-3
GO:0016081 synaptic vesicle docking involved in exocytosis 1.528851e-3
GO:0060534 trachea cartilage development 1.529311e-3
GO:0002051 osteoblast fate commitment 1.529311e-3
GO:0006420 arginyl-tRNA aminoacylation 1.557530e-3
GO:0032277 negative regulation of gonadotropin secretion 1.617428e-3
GO:0090224 regulation of spindle organization 1.618386e-3
GO:0051005 negative regulation of lipoprotein lipase activity 1.652471e-3
GO:0015931 nucleobase-containing compound transport 1.687406e-3
GO:0043243 positive regulation of protein complex disassembly 1.688360e-3
GO:0044249 cellular biosynthetic process 1.702057e-3
GO:0021978 telencephalon regionalization 1.755262e-3
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 1.761150e-3
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.761150e-3
GO:0071105 response to interleukin-11 1.776455e-3
GO:0071624 positive regulation of granulocyte chemotaxis 1.776455e-3
GO:0002368 B cell cytokine production 1.776455e-3
GO:0051684 maintenance of Golgi location 1.776455e-3
GO:0048291 isotype switching to IgG isotypes 1.776455e-3
GO:0046452 dihydrofolate metabolic process 1.776455e-3
GO:0048368 lateral mesoderm development 1.819259e-3
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.829374e-3
GO:0000226 microtubule cytoskeleton organization 1.851451e-3
GO:0035562 negative regulation of chromatin binding 1.856375e-3
GO:0010498 proteasomal protein catabolic process 1.864020e-3
GO:0021546 rhombomere development 1.871616e-3
GO:0060433 bronchus development 1.899039e-3
GO:0071173 spindle assembly checkpoint 1.911203e-3
GO:0060375 regulation of mast cell differentiation 1.926983e-3
GO:2000383 regulation of ectoderm development 2.030091e-3
GO:0033088 negative regulation of immature T cell proliferation in thymus 2.030091e-3
GO:0018393 internal peptidyl-lysine acetylation 2.045952e-3
GO:0051983 regulation of chromosome segregation 2.072887e-3
GO:0045922 negative regulation of fatty acid metabolic process 2.072887e-3
GO:0071206 establishment of protein localization to juxtaparanode region of axon 2.179793e-3
GO:0060168 positive regulation of adenosine receptor signaling pathway 2.179793e-3
GO:0006807 nitrogen compound metabolic process 2.205350e-3
GO:0045292 nuclear mRNA cis splicing, via spliceosome 2.288313e-3
GO:0007094 mitotic cell cycle spindle assembly checkpoint 2.288313e-3
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 2.320988e-3
GO:0003140 determination of left/right asymmetry in lateral mesoderm 2.348239e-3
GO:0001672 regulation of chromatin assembly or disassembly 2.433069e-3
GO:0045626 negative regulation of T-helper 1 cell differentiation 2.502811e-3
GO:0007023 post-chaperonin tubulin folding pathway 2.502811e-3
GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development 2.548368e-3
GO:0060458 right lung development 2.548368e-3
GO:0007228 positive regulation of hh target transcription factor activity 2.548368e-3
GO:0016458 gene silencing 2.625964e-3
GO:0051321 meiotic cell cycle 2.645121e-3
GO:0035404 histone-serine phosphorylation 2.764228e-3
GO:0051252 regulation of RNA metabolic process 2.764559e-3
GO:0071894 histone H2B conserved C-terminal lysine ubiquitination 2.772816e-3
GO:0060574 intestinal epithelial cell maturation 2.772816e-3
GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process 2.772816e-3
GO:0035621 ER to Golgi ceramide transport 2.772816e-3
GO:0007051 spindle organization 2.835002e-3
GO:0043457 regulation of cellular respiration 2.841863e-3
GO:0031536 positive regulation of exit from mitosis 2.841863e-3
GO:0000212 meiotic spindle organization 2.841863e-3
GO:0007168 receptor guanylyl cyclase signaling pathway 2.841863e-3
GO:0060621 negative regulation of cholesterol import 2.880206e-3
GO:0007386 compartment pattern specification 2.880206e-3
GO:0033084 regulation of immature T cell proliferation in thymus 2.886138e-3
GO:0042407 cristae formation 2.887213e-3
GO:0044314 protein K27-linked ubiquitination 2.887213e-3
GO:0018214 protein carboxylation 2.887213e-3
GO:0000059 protein import into nucleus, docking 2.887213e-3
GO:0015724 formate transport 2.887213e-3
GO:0015876 acetyl-CoA transport 2.887213e-3
GO:0045717 negative regulation of fatty acid biosynthetic process 2.966837e-3
GO:0021527 spinal cord association neuron differentiation 3.109049e-3
GO:0007221 positive regulation of transcription of Notch receptor target 3.179432e-3
GO:0014807 regulation of somitogenesis 3.220143e-3
GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 3.220143e-3
GO:0016072 rRNA metabolic process 3.243616e-3
GO:0090343 positive regulation of cell aging 3.288883e-3
GO:0043241 protein complex disassembly 3.446898e-3
GO:0016577 histone demethylation 3.452683e-3
GO:0045875 negative regulation of sister chromatid cohesion 3.560827e-3
GO:0051238 sequestering of metal ion 3.592336e-3
GO:0021843 substrate-independent telencephalic tangential interneuron migration 3.592336e-3
GO:0030201 heparan sulfate proteoglycan metabolic process 3.735530e-3
GO:0019673 GDP-mannose metabolic process 3.891141e-3
GO:0001539 ciliary or flagellar motility 3.935523e-3
GO:0045657 positive regulation of monocyte differentiation 3.996430e-3
GO:0090074 negative regulation of protein homodimerization activity 4.015215e-3
GO:0002069 columnar/cuboidal epithelial cell maturation 4.015215e-3
GO:0021754 facial nucleus development 4.015215e-3
GO:0032328 alanine transport 4.093564e-3
GO:0014741 negative regulation of muscle hypertrophy 4.227691e-3
GO:0060620 regulation of cholesterol import 4.345295e-3
GO:0046853 inositol or phosphatidylinositol phosphorylation 4.347372e-3
GO:0019509 L-methionine salvage from methylthioadenosine 4.347372e-3
GO:0006355 regulation of transcription, DNA-dependent 4.413364e-3
GO:0033119 negative regulation of RNA splicing 4.439247e-3
GO:0042473 outer ear morphogenesis 4.540793e-3
GO:0072040 negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis 4.546100e-3
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway 4.572914e-3
GO:0006418 tRNA aminoacylation for protein translation 4.602505e-3
GO:0031577 spindle checkpoint 4.652765e-3
GO:0021904 dorsal/ventral neural tube patterning 4.693560e-3
GO:0060712 spongiotrophoblast layer development 4.840376e-3
GO:0045624 positive regulation of T-helper cell differentiation 4.845603e-3
GO:0032055 negative regulation of translation in response to stress 4.929705e-3
GO:0038007 netrin-activated signaling pathway 4.929705e-3
GO:0031584 activation of phospholipase D activity 4.929705e-3
GO:0060683 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling 5.037629e-3
GO:0021930 cerebellar granule cell precursor proliferation 5.037629e-3
GO:0032465 regulation of cytokinesis 5.063987e-3
GO:0070831 basement membrane assembly 5.257083e-3
GO:0042789 mRNA transcription from RNA polymerase II promoter 5.257083e-3
GO:0018364 peptidyl-glutamine methylation 5.257083e-3
GO:0008208 C21-steroid hormone catabolic process 5.257083e-3
GO:0007143 female meiosis 5.308484e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 5.398149e-3
GO:0033962 cytoplasmic mRNA processing body assembly 5.451493e-3
GO:0051028 mRNA transport 5.492251e-3
GO:0045652 regulation of megakaryocyte differentiation 5.515189e-3
GO:0072203 cell proliferation involved in metanephros development 5.647007e-3
GO:0032784 regulation of transcription elongation, DNA-dependent 5.822295e-3
GO:0034382 chylomicron remnant clearance 5.873988e-3
GO:0006656 phosphatidylcholine biosynthetic process 5.964666e-3
GO:0034227 tRNA thio-modification 6.254117e-3
GO:0046607 positive regulation of centrosome cycle 6.262580e-3
GO:0060217 hemangioblast cell differentiation 6.262580e-3
GO:0045799 positive regulation of chromatin assembly or disassembly 6.262580e-3
GO:0032927 positive regulation of activin receptor signaling pathway 6.262580e-3
GO:0019264 glycine biosynthetic process from serine 6.262580e-3
GO:0080164 regulation of nitric oxide metabolic process 6.304670e-3
GO:0017187 peptidyl-glutamic acid carboxylation 6.304670e-3
GO:0006683 galactosylceramide catabolic process 6.304670e-3
GO:0016482 cytoplasmic transport 6.304670e-3
GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway 6.315360e-3
GO:0070935 3'-UTR-mediated mRNA stabilization 6.315360e-3
GO:0006422 aspartyl-tRNA aminoacylation 6.315360e-3
GO:0008380 RNA splicing 6.405128e-3
GO:0016539 intein-mediated protein splicing 6.518718e-3
GO:0090307 spindle assembly involved in mitosis 6.547920e-3
GO:0006913 nucleocytoplasmic transport 6.793785e-3
GO:0009452 RNA capping 6.842387e-3
GO:0070170 regulation of tooth mineralization 6.852777e-3
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 6.852777e-3
GO:0002740 negative regulation of cytokine secretion involved in immune response 6.879308e-3
GO:0045685 regulation of glial cell differentiation 6.919592e-3
GO:2000112 regulation of cellular macromolecule biosynthetic process 7.086025e-3
GO:0043966 histone H3 acetylation 7.247743e-3
GO:0045919 positive regulation of cytolysis 7.276679e-3
GO:0010512 negative regulation of phosphatidylinositol biosynthetic process 7.308813e-3
GO:0021568 rhombomere 2 development 7.308813e-3
GO:0009113 purine base biosynthetic process 7.317829e-3
GO:0051169 nuclear transport 7.325484e-3
GO:0006611 protein export from nucleus 7.731482e-3
GO:0046836 glycolipid transport 7.905939e-3
GO:0042996 regulation of Golgi to plasma membrane protein transport 7.905939e-3
GO:0002642 positive regulation of immunoglobulin biosynthetic process 7.905939e-3
GO:0072144 glomerular mesangial cell development 7.966809e-3
GO:0045014 negative regulation of transcription by glucose 7.966809e-3
GO:0046847 filopodium assembly 8.033689e-3
GO:0090042 tubulin deacetylation 8.080073e-3
GO:0072355 histone H3-T3 phosphorylation 8.080073e-3
GO:0070846 Hsp90 deacetylation 8.080073e-3
GO:0050928 negative regulation of positive chemotaxis 8.080073e-3
GO:0046784 intronless viral mRNA export from host nucleus 8.128712e-3
GO:0061046 regulation of branching involved in lung morphogenesis 8.146860e-3
GO:0007096 regulation of exit from mitosis 8.146860e-3
GO:0051590 positive regulation of neurotransmitter transport 8.146860e-3
GO:0048227 plasma membrane to endosome transport 8.156042e-3
GO:2000682 positive regulation of rubidium ion transport 8.156042e-3
GO:0035826 rubidium ion transport 8.156042e-3
GO:2000688 positive regulation of rubidium ion transmembrane transporter activity 8.156042e-3
GO:0001682 tRNA 5'-leader removal 8.156042e-3
GO:0016078 tRNA catabolic process 8.156042e-3
GO:0032065 cortical protein anchoring 8.156042e-3
GO:0044237 cellular metabolic process 8.209727e-3
GO:0009648 photoperiodism 8.264896e-3
GO:0021571 rhombomere 5 development 8.296151e-3
GO:0006413 translational initiation 8.584219e-3
GO:0009081 branched chain family amino acid metabolic process 8.808345e-3
GO:0015824 proline transport 9.105386e-3
GO:0050713 negative regulation of interleukin-1 beta secretion 9.161315e-3
GO:0060438 trachea development 9.184309e-3
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 9.288092e-3
GO:0071459 protein localization to chromosome, centromeric region 9.288092e-3
GO:0048599 oocyte development 9.374132e-3
GO:0043484 regulation of RNA splicing 9.419187e-3
GO:0021516 dorsal spinal cord development 9.422381e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 9.422381e-3
GO:0051438 regulation of ubiquitin-protein ligase activity 9.560888e-3
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 9.575657e-3
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 9.588922e-3
GO:0060659 nipple sheath formation 9.873017e-3
GO:0071877 regulation of adrenergic receptor signaling pathway 9.873017e-3
GO:0060649 mammary gland bud elongation 9.873017e-3
GO:0046952 ketone body catabolic process 9.873017e-3
GO:0010722 regulation of ferrochelatase activity 9.873017e-3
GO:0000042 protein targeting to Golgi 9.929504e-3
GO:0060439 trachea morphogenesis 9.970686e-3
GO:0045686 negative regulation of glial cell differentiation 1.003560e-2
GO:0000731 DNA synthesis involved in DNA repair 1.004092e-2
GO:0045654 positive regulation of megakaryocyte differentiation 1.004092e-2
GO:0015012 heparan sulfate proteoglycan biosynthetic process 1.013649e-2
GO:0006448 regulation of translational elongation 1.013649e-2
GO:0030219 megakaryocyte differentiation 1.041509e-2
GO:0043624 cellular protein complex disassembly 1.041509e-2
GO:0018022 peptidyl-lysine methylation 1.041509e-2
GO:0060244 negative regulation of cell proliferation involved in contact inhibition 1.049211e-2
GO:0061048 negative regulation of branching involved in lung morphogenesis 1.049211e-2
GO:0045994 positive regulation of translational initiation by iron 1.049211e-2
GO:0034116 positive regulation of heterotypic cell-cell adhesion 1.049211e-2
GO:0002037 negative regulation of L-glutamate transport 1.049211e-2
GO:0009058 biosynthetic process 1.051538e-2
GO:0030718 germ-line stem cell maintenance 1.052544e-2
GO:0060535 trachea cartilage morphogenesis 1.054731e-2
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 1.054731e-2
GO:0051225 spindle assembly 1.065934e-2
GO:0006475 internal protein amino acid acetylation 1.066189e-2
GO:0032924 activin receptor signaling pathway 1.079505e-2
GO:0045627 positive regulation of T-helper 1 cell differentiation 1.091066e-2
GO:0051313 attachment of spindle microtubules to chromosome 1.091066e-2
GO:0006482 protein demethylation 1.117066e-2
GO:0072092 ureteric bud invasion 1.165146e-2
GO:0046323 glucose import 1.165146e-2
GO:0035507 regulation of myosin-light-chain-phosphatase activity 1.165146e-2
GO:0045218 zonula adherens maintenance 1.182408e-2
GO:0042254 ribosome biogenesis 1.184418e-2
GO:0040015 negative regulation of multicellular organism growth 1.191150e-2
GO:0034661 ncRNA catabolic process 1.211869e-2
GO:0048710 regulation of astrocyte differentiation 1.219481e-2
GO:0034553 mitochondrial respiratory chain complex II assembly 1.227821e-2
GO:0018095 protein polyglutamylation 1.227821e-2
GO:0009994 oocyte differentiation 1.229084e-2
GO:0007126 meiosis 1.242926e-2
GO:0034067 protein localization in Golgi apparatus 1.251792e-2
GO:0006544 glycine metabolic process 1.256839e-2
GO:0006182 cGMP biosynthetic process 1.256839e-2
GO:0010985 negative regulation of lipoprotein particle clearance 1.258213e-2
GO:0060167 regulation of adenosine receptor signaling pathway 1.290091e-2
GO:0007509 mesoderm migration involved in gastrulation 1.307981e-2
GO:0035195 gene silencing by miRNA 1.328505e-2
GO:0034959 endothelin maturation 1.333733e-2
GO:0010814 substance P catabolic process 1.333733e-2
GO:0033278 cell proliferation in midbrain 1.333733e-2
GO:0030950 establishment or maintenance of actin cytoskeleton polarity 1.333733e-2
GO:0010816 calcitonin catabolic process 1.333733e-2
GO:0045653 negative regulation of megakaryocyte differentiation 1.348858e-2
GO:0006364 rRNA processing 1.358876e-2
GO:0046639 negative regulation of alpha-beta T cell differentiation 1.393984e-2
GO:0070936 protein K48-linked ubiquitination 1.418420e-2
GO:0071711 basement membrane organization 1.437041e-2
GO:0010468 regulation of gene expression 1.457683e-2
GO:0042297 vocal learning 1.476117e-2
GO:0042268 regulation of cytolysis 1.476117e-2
GO:0032981 mitochondrial respiratory chain complex I assembly 1.491054e-2
GO:0006396 RNA processing 1.507589e-2
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1.508255e-2
GO:0019230 proprioception 1.508255e-2
GO:0046532 regulation of photoreceptor cell differentiation 1.511340e-2
GO:0032218 riboflavin transport 1.515844e-2
GO:0050861 positive regulation of B cell receptor signaling pathway 1.515844e-2
GO:0006235 dTTP biosynthetic process 1.515844e-2
GO:0060192 negative regulation of lipase activity 1.560380e-2
GO:0001573 ganglioside metabolic process 1.585938e-2
GO:0034720 histone H3-K4 demethylation 1.598947e-2
GO:0007062 sister chromatid cohesion 1.615381e-2
GO:0032006 regulation of TOR signaling cascade 1.649064e-2
GO:0043153 entrainment of circadian clock by photoperiod 1.649203e-2
GO:0060677 ureteric bud elongation 1.666741e-2
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development 1.697742e-2
GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter 1.697742e-2
GO:0010312 detoxification of zinc ion 1.697742e-2
GO:0051030 snRNA transport 1.697742e-2
GO:0034660 ncRNA metabolic process 1.698684e-2
GO:0021871 forebrain regionalization 1.734377e-2
GO:0033131 regulation of glucokinase activity 1.736874e-2
GO:0072033 renal vesicle formation 1.736874e-2
GO:0006368 transcription elongation from RNA polymerase II promoter 1.736874e-2
GO:0046112 nucleobase biosynthetic process 1.737705e-2
GO:0009083 branched chain family amino acid catabolic process 1.782003e-2
GO:0034393 positive regulation of smooth muscle cell apoptosis 1.783812e-2
GO:0033133 positive regulation of glucokinase activity 1.800554e-2
GO:0072205 metanephric collecting duct development 1.811688e-2
GO:0009086 methionine biosynthetic process 1.823605e-2
GO:0031497 chromatin assembly 1.824687e-2
GO:0031576 G2/M transition checkpoint 1.828829e-2
GO:0021884 forebrain neuron development 1.837843e-2
GO:0034134 toll-like receptor 2 signaling pathway 1.846579e-2
GO:0003418 growth plate cartilage chondrocyte differentiation 1.846579e-2
GO:0060484 lung-associated mesenchyme development 1.857300e-2
GO:0040034 regulation of development, heterochronic 1.870894e-2
GO:0048733 sebaceous gland development 1.872578e-2
GO:0007529 establishment of synaptic specificity at neuromuscular junction 1.872578e-2
GO:0006473 protein acetylation 1.915128e-2
GO:0018283 iron incorporation into metallo-sulfur cluster 1.928311e-2
GO:0071930 negative regulation of transcription involved in G1/S phase of mitotic cell cycle 1.928311e-2
GO:0048505 regulation of timing of cell differentiation 1.937818e-2
GO:0006511 ubiquitin-dependent protein catabolic process 1.944060e-2
GO:0045792 negative regulation of cell size 1.950758e-2
GO:0008078 mesodermal cell migration 1.950758e-2
GO:0006259 DNA metabolic process 1.969007e-2
GO:0051188 cofactor biosynthetic process 1.969792e-2
GO:0035066 positive regulation of histone acetylation 1.989002e-2
GO:0090303 positive regulation of wound healing 2.020539e-2
GO:0010511 regulation of phosphatidylinositol biosynthetic process 2.020539e-2
GO:0043632 modification-dependent macromolecule catabolic process 2.045489e-2
GO:0022613 ribonucleoprotein complex biogenesis 2.052616e-2
GO:0071557 histone H3-K27 demethylation 2.113952e-2
GO:0010501 RNA secondary structure unwinding 2.113952e-2
GO:0035574 histone H4-K20 demethylation 2.113952e-2
GO:0032693 negative regulation of interleukin-10 production 2.147927e-2
GO:0051151 negative regulation of smooth muscle cell differentiation 2.147927e-2
GO:0006287 base-excision repair, gap-filling 2.147927e-2
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 2.163969e-2
GO:0046103 inosine biosynthetic process 2.163971e-2
GO:0006154 adenosine catabolic process 2.163971e-2
GO:0072003 kidney rudiment formation 2.170872e-2
GO:0032288 myelin assembly 2.177106e-2
GO:0060816 random inactivation of X chromosome 2.190218e-2
GO:2000706 negative regulation of dense core granule biogenesis 2.190218e-2
GO:0003430 growth plate cartilage chondrocyte growth 2.190218e-2
GO:0060385 axonogenesis involved in innervation 2.190218e-2
GO:2000798 negative regulation of amniotic stem cell differentiation 2.190218e-2
GO:0006256 UDP catabolic process 2.190218e-2
GO:0031468 nuclear envelope reassembly 2.190218e-2
GO:0045004 DNA replication proofreading 2.190218e-2
GO:0048632 negative regulation of skeletal muscle tissue growth 2.190218e-2
GO:0045669 positive regulation of osteoblast differentiation 2.207264e-2
GO:0043990 histone H2A-S1 phosphorylation 2.237490e-2
GO:0043048 dolichyl monophosphate biosynthetic process 2.237490e-2
GO:0042335 cuticle development 2.237490e-2
GO:0043000 Golgi to plasma membrane CFTR protein transport 2.237490e-2
GO:0070370 cellular heat acclimation 2.237490e-2