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Novel motif:74

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name:motif74_TTKAAAY

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0023052 signaling 1.695961e-14
GO:0002376 immune system process 2.009654e-14
GO:0032501 multicellular organismal process 1.710495e-13
GO:0042113 B cell activation 5.550000e-13
GO:0050896 response to stimulus 6.565129e-13
GO:0007154 cell communication 2.483492e-12
GO:0001775 cell activation 3.276586e-12
GO:0007165 signal transduction 8.856576e-12
GO:0032502 developmental process 1.960367e-11
GO:0007275 multicellular organismal development 3.524612e-11
GO:0048856 anatomical structure development 5.753049e-11
GO:0042060 wound healing 7.324925e-11
GO:0072358 cardiovascular system development 8.365398e-11
GO:0048513 organ development 1.307536e-10
GO:0051716 cellular response to stimulus 1.427296e-10
GO:0009888 tissue development 7.588341e-10
GO:0048731 system development 9.848092e-10
GO:0055013 cardiac muscle cell development 1.110977e-9
GO:0015705 iodide transport 2.747903e-9
GO:0002520 immune system development 4.470285e-9
GO:2000725 regulation of cardiac muscle cell differentiation 4.971151e-9
GO:0006590 thyroid hormone generation 6.360040e-9
GO:0048468 cell development 1.020601e-8
GO:0050794 regulation of cellular process 1.112367e-8
GO:0048534 hemopoietic or lymphoid organ development 1.125154e-8
GO:0019220 regulation of phosphate metabolic process 1.177083e-8
GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification 1.600054e-8
GO:0055003 cardiac myofibril assembly 1.827023e-8
GO:0035051 cardiac cell differentiation 2.209319e-8
GO:0046649 lymphocyte activation 3.044550e-8
GO:0050867 positive regulation of cell activation 3.162577e-8
GO:0045321 leukocyte activation 3.765529e-8
GO:0007507 heart development 3.860731e-8
GO:0045056 transcytosis 3.902775e-8
GO:0050870 positive regulation of T cell activation 3.989095e-8
GO:0051246 regulation of protein metabolic process 5.627643e-8
GO:0042221 response to chemical stimulus 5.855716e-8
GO:0055007 cardiac muscle cell differentiation 6.645848e-8
GO:0050789 regulation of biological process 7.210140e-8
GO:2001016 positive regulation of skeletal muscle cell differentiation 1.156741e-7
GO:0002696 positive regulation of leukocyte activation 1.236362e-7
GO:2000987 positive regulation of behavioral fear response 1.490120e-7
GO:2000727 positive regulation of cardiac muscle cell differentiation 1.490120e-7
GO:0003138 primary heart field specification 1.490120e-7
GO:0003185 sinoatrial valve morphogenesis 1.490120e-7
GO:0035984 cellular response to trichostatin A 1.490120e-7
GO:0007166 cell surface receptor linked signaling pathway 1.718734e-7
GO:0051251 positive regulation of lymphocyte activation 1.853651e-7
GO:0048869 cellular developmental process 1.980425e-7
GO:0065007 biological regulation 2.643497e-7
GO:0040007 growth 2.882504e-7
GO:0006880 intracellular sequestering of iron ion 3.053025e-7
GO:0060420 regulation of heart growth 3.058959e-7
GO:0042325 regulation of phosphorylation 3.246179e-7
GO:0030878 thyroid gland development 3.359476e-7
GO:0030098 lymphocyte differentiation 3.614293e-7
GO:0042551 neuron maturation 3.860991e-7
GO:0060045 positive regulation of cardiac muscle cell proliferation 4.033324e-7
GO:0065008 regulation of biological quality 4.128667e-7
GO:0002244 hemopoietic progenitor cell differentiation 4.339267e-7
GO:0051592 response to calcium ion 4.538535e-7
GO:0009611 response to wounding 4.541519e-7
GO:0032268 regulation of cellular protein metabolic process 4.565571e-7
GO:0003211 cardiac ventricle formation 4.681569e-7
GO:0030183 B cell differentiation 4.776844e-7
GO:0048608 reproductive structure development 5.015830e-7
GO:0044272 sulfur compound biosynthetic process 5.094468e-7
GO:0042264 peptidyl-aspartic acid hydroxylation 5.172684e-7
GO:0055021 regulation of cardiac muscle tissue growth 5.268908e-7
GO:0002262 myeloid cell homeostasis 5.618658e-7
GO:0030097 hemopoiesis 5.645878e-7
GO:0030154 cell differentiation 5.707844e-7
GO:0015012 heparan sulfate proteoglycan biosynthetic process 6.138481e-7
GO:0050777 negative regulation of immune response 6.303049e-7
GO:0009268 response to pH 6.456550e-7
GO:0002440 production of molecular mediator of immune response 6.983233e-7
GO:0003008 system process 7.716079e-7
GO:0002683 negative regulation of immune system process 9.302698e-7
GO:0003179 heart valve morphogenesis 9.791221e-7
GO:0007076 mitotic chromosome condensation 1.137359e-6
GO:0048769 sarcomerogenesis 1.194510e-6
GO:0051249 regulation of lymphocyte activation 1.203494e-6
GO:0001568 blood vessel development 1.273754e-6
GO:0010692 regulation of alkaline phosphatase activity 1.273907e-6
GO:0048729 tissue morphogenesis 1.290293e-6
GO:0055005 ventricular cardiac myofibril development 1.333540e-6
GO:0046485 ether lipid metabolic process 1.375967e-6
GO:0006887 exocytosis 1.399314e-6
GO:0001932 regulation of protein phosphorylation 1.420974e-6
GO:0042403 thyroid hormone metabolic process 1.564290e-6
GO:0046620 regulation of organ growth 1.575996e-6
GO:2000822 regulation of behavioral fear response 1.648775e-6
GO:0001933 negative regulation of protein phosphorylation 1.699703e-6
GO:0045161 neuronal ion channel clustering 1.843010e-6
GO:0001944 vasculature development 2.148287e-6
GO:0031399 regulation of protein modification process 2.315451e-6
GO:2000111 positive regulation of macrophage apoptosis 2.508063e-6
GO:0010694 positive regulation of alkaline phosphatase activity 2.725194e-6
GO:0003170 heart valve development 2.871300e-6
GO:0010033 response to organic substance 2.992738e-6
GO:0030001 metal ion transport 3.053371e-6
GO:0030240 skeletal muscle thin filament assembly 3.290918e-6
GO:0051450 myoblast proliferation 3.348095e-6
GO:0045666 positive regulation of neuron differentiation 3.532255e-6
GO:0070447 positive regulation of oligodendrocyte progenitor proliferation 3.976521e-6
GO:0051179 localization 4.059547e-6
GO:0046883 regulation of hormone secretion 4.070907e-6
GO:0052547 regulation of peptidase activity 4.695500e-6
GO:0051155 positive regulation of striated muscle cell differentiation 4.830471e-6
GO:0009820 alkaloid metabolic process 4.841582e-6
GO:0060043 regulation of cardiac muscle cell proliferation 5.400326e-6
GO:0009790 embryo development 5.522867e-6
GO:0002320 lymphoid progenitor cell differentiation 5.586849e-6
GO:0014706 striated muscle tissue development 5.723126e-6
GO:0006955 immune response 5.752060e-6
GO:0000070 mitotic sister chromatid segregation 5.811705e-6
GO:0051238 sequestering of metal ion 7.196304e-6
GO:0060537 muscle tissue development 7.287402e-6
GO:0010646 regulation of cell communication 7.418527e-6
GO:0045727 positive regulation of translation 7.631086e-6
GO:0046427 positive regulation of JAK-STAT cascade 7.817404e-6
GO:0048066 developmental pigmentation 7.938827e-6
GO:2000109 regulation of macrophage apoptosis 7.993045e-6
GO:0002576 platelet degranulation 8.058041e-6
GO:0046635 positive regulation of alpha-beta T cell activation 8.309618e-6
GO:0006950 response to stress 9.845366e-6
GO:0050865 regulation of cell activation 9.906124e-6
GO:0007521 muscle cell fate determination 1.014181e-5
GO:0060025 regulation of synaptic activity 1.015338e-5
GO:0048738 cardiac muscle tissue development 1.016863e-5
GO:0002369 T cell cytokine production 1.150113e-5
GO:0007599 hemostasis 1.203233e-5
GO:0048585 negative regulation of response to stimulus 1.213681e-5
GO:0045769 negative regulation of asymmetric cell division 1.219663e-5
GO:2000409 positive regulation of T cell extravasation 1.219663e-5
GO:0043310 negative regulation of eosinophil degranulation 1.219663e-5
GO:0035705 T-helper 17 cell chemotaxis 1.219663e-5
GO:0035696 monocyte extravasation 1.219663e-5
GO:0050931 pigment cell differentiation 1.248660e-5
GO:0008406 gonad development 1.334921e-5
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 1.349644e-5
GO:0010737 protein kinase A signaling cascade 1.364027e-5
GO:0000819 sister chromatid segregation 1.405295e-5
GO:0050878 regulation of body fluid levels 1.443500e-5
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 1.450100e-5
GO:0002694 regulation of leukocyte activation 1.499645e-5
GO:0050853 B cell receptor signaling pathway 1.514802e-5
GO:0007596 blood coagulation 1.663060e-5
GO:0055082 cellular chemical homeostasis 1.669091e-5
GO:0046638 positive regulation of alpha-beta T cell differentiation 1.774090e-5
GO:0046888 negative regulation of hormone secretion 1.776475e-5
GO:0031641 regulation of myelination 1.859255e-5
GO:0048863 stem cell differentiation 1.930480e-5
GO:0052548 regulation of endopeptidase activity 1.995664e-5
GO:0007517 muscle organ development 2.008018e-5
GO:0002820 negative regulation of adaptive immune response 2.026956e-5
GO:0055001 muscle cell development 2.027737e-5
GO:0003006 developmental process involved in reproduction 2.063343e-5
GO:0055024 regulation of cardiac muscle tissue development 2.150056e-5
GO:0048646 anatomical structure formation involved in morphogenesis 2.155605e-5
GO:0048536 spleen development 2.212326e-5
GO:0032940 secretion by cell 2.235820e-5
GO:0009893 positive regulation of metabolic process 2.381877e-5
GO:0051094 positive regulation of developmental process 2.836963e-5
GO:0002328 pro-B cell differentiation 2.860301e-5
GO:0016477 cell migration 2.870110e-5
GO:0007040 lysosome organization 3.036207e-5
GO:0048514 blood vessel morphogenesis 3.049953e-5
GO:0042327 positive regulation of phosphorylation 3.170878e-5
GO:0006556 S-adenosylmethionine biosynthetic process 3.176890e-5
GO:0007229 integrin-mediated signaling pathway 3.284713e-5
GO:0045937 positive regulation of phosphate metabolic process 3.314120e-5
GO:0060442 branching involved in prostate gland morphogenesis 3.353480e-5
GO:0030318 melanocyte differentiation 3.398563e-5
GO:0018126 protein hydroxylation 3.457028e-5
GO:0007417 central nervous system development 3.485080e-5
GO:0032095 regulation of response to food 3.666491e-5
GO:0030168 platelet activation 3.676501e-5
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.876885e-5
GO:0007059 chromosome segregation 3.917355e-5
GO:2000116 regulation of cysteine-type endopeptidase activity 4.061277e-5
GO:0009786 regulation of asymmetric cell division 4.611713e-5
GO:0009100 glycoprotein metabolic process 4.877375e-5
GO:0008343 adult feeding behavior 4.899129e-5
GO:0050863 regulation of T cell activation 4.962076e-5
GO:0030003 cellular cation homeostasis 4.997202e-5
GO:0071374 cellular response to parathyroid hormone stimulus 5.104313e-5
GO:0061061 muscle structure development 5.195242e-5
GO:0008584 male gonad development 5.301135e-5
GO:0050793 regulation of developmental process 5.305215e-5
GO:0016192 vesicle-mediated transport 5.501422e-5
GO:0006875 cellular metal ion homeostasis 5.585432e-5
GO:0002467 germinal center formation 5.587566e-5
GO:0045621 positive regulation of lymphocyte differentiation 5.629826e-5
GO:0045927 positive regulation of growth 5.645196e-5
GO:0030166 proteoglycan biosynthetic process 5.668223e-5
GO:0001821 histamine secretion 5.675358e-5
GO:0048598 embryonic morphogenesis 5.730100e-5
GO:0055080 cation homeostasis 5.901977e-5
GO:0051240 positive regulation of multicellular organismal process 5.989145e-5
GO:0019725 cellular homeostasis 6.313691e-5
GO:0006936 muscle contraction 6.342420e-5
GO:0040008 regulation of growth 6.354211e-5
GO:0045582 positive regulation of T cell differentiation 6.363779e-5
GO:0031032 actomyosin structure organization 6.542491e-5
GO:0042246 tissue regeneration 6.569913e-5
GO:0050900 leukocyte migration 6.570110e-5
GO:0019226 transmission of nerve impulse 6.756302e-5
GO:0045663 positive regulation of myoblast differentiation 6.826519e-5
GO:0007155 cell adhesion 6.902149e-5
GO:0006811 ion transport 7.161640e-5
GO:0090073 positive regulation of protein homodimerization activity 7.490889e-5
GO:0002250 adaptive immune response 7.501790e-5
GO:0030182 neuron differentiation 7.717288e-5
GO:0061337 cardiac conduction 7.763301e-5
GO:0032989 cellular component morphogenesis 7.871043e-5
GO:0060711 labyrinthine layer development 7.890323e-5
GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development 8.109170e-5
GO:0045137 development of primary sexual characteristics 8.215821e-5
GO:0045597 positive regulation of cell differentiation 8.521294e-5
GO:0050877 neurological system process 8.671642e-5
GO:0030241 skeletal muscle myosin thick filament assembly 8.744418e-5
GO:0007219 Notch signaling pathway 8.780763e-5
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 9.003927e-5
GO:0006873 cellular ion homeostasis 9.096763e-5
GO:0030239 myofibril assembly 9.100488e-5
GO:0048762 mesenchymal cell differentiation 9.247451e-5
GO:0006928 cellular component movement 9.490054e-5
GO:0002521 leukocyte differentiation 9.885578e-5
GO:0042063 gliogenesis 9.902415e-5
GO:0019674 NAD metabolic process 9.981395e-5
GO:0046546 development of primary male sexual characteristics 1.018712e-4
GO:0031325 positive regulation of cellular metabolic process 1.037935e-4
GO:0042127 regulation of cell proliferation 1.075542e-4
GO:0006790 sulfur compound metabolic process 1.076236e-4
GO:2001013 epithelial cell proliferation involve in renal tubule morphogenesis 1.080490e-4
GO:0071498 cellular response to fluid shear stress 1.080490e-4
GO:0051608 histamine transport 1.081822e-4
GO:0055065 metal ion homeostasis 1.092592e-4
GO:0032879 regulation of localization 1.095512e-4
GO:0048589 developmental growth 1.104388e-4
GO:0006417 regulation of translation 1.115547e-4
GO:0055015 ventricular cardiac muscle cell development 1.119038e-4
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 1.159486e-4
GO:0006940 regulation of smooth muscle contraction 1.162389e-4
GO:0071840 cellular component organization or biogenesis 1.169346e-4
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 1.183036e-4
GO:0019227 neuronal action potential propagation 1.187181e-4
GO:0002819 regulation of adaptive immune response 1.190722e-4
GO:0051797 regulation of hair follicle development 1.237399e-4
GO:0051641 cellular localization 1.277768e-4
GO:0010092 specification of organ identity 1.316691e-4
GO:0045667 regulation of osteoblast differentiation 1.330165e-4
GO:0045055 regulated secretory pathway 1.333403e-4
GO:0035690 cellular response to drug 1.338982e-4
GO:0042534 regulation of tumor necrosis factor biosynthetic process 1.344752e-4
GO:0030521 androgen receptor signaling pathway 1.348480e-4
GO:0030201 heparan sulfate proteoglycan metabolic process 1.428128e-4
GO:0002443 leukocyte mediated immunity 1.433766e-4
GO:0080090 regulation of primary metabolic process 1.442476e-4
GO:0001816 cytokine production 1.448092e-4
GO:0048634 regulation of muscle organ development 1.481128e-4
GO:0046496 nicotinamide nucleotide metabolic process 1.522339e-4
GO:0050801 ion homeostasis 1.537925e-4
GO:0010820 positive regulation of T cell chemotaxis 1.597147e-4
GO:0046637 regulation of alpha-beta T cell differentiation 1.619908e-4
GO:0046661 male sex differentiation 1.631551e-4
GO:0051661 maintenance of centrosome location 1.632983e-4
GO:0051146 striated muscle cell differentiation 1.661147e-4
GO:0045844 positive regulation of striated muscle tissue development 1.663329e-4
GO:0070253 somatostatin secretion 1.676527e-4
GO:0032812 positive regulation of epinephrine secretion 1.676527e-4
GO:0010604 positive regulation of macromolecule metabolic process 1.692841e-4
GO:0021872 forebrain generation of neurons 1.731754e-4
GO:0060255 regulation of macromolecule metabolic process 1.732796e-4
GO:0006959 humoral immune response 1.755610e-4
GO:0002367 cytokine production involved in immune response 1.756488e-4
GO:0042326 negative regulation of phosphorylation 1.778052e-4
GO:0009617 response to bacterium 1.792788e-4
GO:0048643 positive regulation of skeletal muscle tissue development 1.798835e-4
GO:0046903 secretion 1.805442e-4
GO:0019222 regulation of metabolic process 1.810785e-4
GO:0048878 chemical homeostasis 1.815009e-4
GO:0001890 placenta development 1.817297e-4
GO:0042100 B cell proliferation 1.872268e-4
GO:0003007 heart morphogenesis 1.876957e-4
GO:0010666 positive regulation of cardiac muscle cell apoptosis 1.886243e-4
GO:0001655 urogenital system development 1.924653e-4
GO:0014866 skeletal myofibril assembly 1.961756e-4
GO:0002377 immunoglobulin production 1.963600e-4
GO:0072160 nephron tubule epithelial cell differentiation 1.974096e-4
GO:0031295 T cell costimulation 1.985131e-4
GO:0010038 response to metal ion 2.048904e-4
GO:0006029 proteoglycan metabolic process 2.054100e-4
GO:0009791 post-embryonic development 2.064957e-4
GO:0001543 ovarian follicle rupture 2.080892e-4
GO:0051495 positive regulation of cytoskeleton organization 2.133574e-4
GO:0071107 response to parathyroid hormone stimulus 2.143568e-4
GO:0010613 positive regulation of cardiac muscle hypertrophy 2.144971e-4
GO:0042634 regulation of hair cycle 2.207053e-4
GO:0051234 establishment of localization 2.222446e-4
GO:0010647 positive regulation of cell communication 2.226046e-4
GO:0001967 suckling behavior 2.261730e-4
GO:0050790 regulation of catalytic activity 2.263702e-4
GO:0021629 olfactory nerve structural organization 2.277585e-4
GO:0072503 cellular divalent inorganic cation homeostasis 2.312881e-4
GO:0003139 secondary heart field specification 2.325512e-4
GO:0045787 positive regulation of cell cycle 2.384133e-4
GO:0051093 negative regulation of developmental process 2.399612e-4
GO:0009967 positive regulation of signal transduction 2.435196e-4
GO:0048864 stem cell development 2.442175e-4
GO:0030534 adult behavior 2.447856e-4
GO:0050435 beta-amyloid metabolic process 2.489169e-4
GO:2000534 positive regulation of renal albumin absorption 2.514746e-4
GO:2000481 positive regulation of cAMP-dependent protein kinase activity 2.514746e-4
GO:0070994 detection of oxidative stress 2.514746e-4
GO:2000461 negative regulation of eukaryotic cell surface binding 2.514746e-4
GO:2000478 positive regulation of metanephric glomerular visceral epithelial cell development 2.514746e-4
GO:0035108 limb morphogenesis 2.519084e-4
GO:0065009 regulation of molecular function 2.519669e-4
GO:0000962 positive regulation of mitochondrial RNA catabolic process 2.545470e-4
GO:0000965 mitochondrial RNA 3'-end processing 2.545470e-4
GO:0000958 mitochondrial mRNA catabolic process 2.545470e-4
GO:0008283 cell proliferation 2.549634e-4
GO:0006911 phagocytosis, engulfment 2.549960e-4
GO:0014853 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction 2.607102e-4
GO:0010557 positive regulation of macromolecule biosynthetic process 2.620247e-4
GO:0030199 collagen fibril organization 2.632822e-4
GO:0032269 negative regulation of cellular protein metabolic process 2.676761e-4
GO:2000026 regulation of multicellular organismal development 2.731212e-4
GO:0001960 negative regulation of cytokine-mediated signaling pathway 2.754537e-4
GO:0015820 leucine transport 2.836037e-4
GO:0007389 pattern specification process 2.938886e-4
GO:0034765 regulation of ion transmembrane transport 2.958098e-4
GO:0006874 cellular calcium ion homeostasis 2.968806e-4
GO:0010952 positive regulation of peptidase activity 2.972895e-4
GO:0055002 striated muscle cell development 2.990749e-4
GO:0007033 vacuole organization 3.009632e-4
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 3.009684e-4
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 3.017435e-4
GO:0035910 ascending aorta morphogenesis 3.017435e-4
GO:0051798 positive regulation of hair follicle development 3.079250e-4
GO:0023056 positive regulation of signaling 3.089308e-4
GO:0006518 peptide metabolic process 3.107151e-4
GO:0048666 neuron development 3.207009e-4
GO:0002009 morphogenesis of an epithelium 3.304229e-4
GO:0051893 regulation of focal adhesion assembly 3.409415e-4
GO:0016198 axon choice point recognition 3.462902e-4
GO:0006878 cellular copper ion homeostasis 3.477869e-4
GO:0032098 regulation of appetite 3.483343e-4
GO:0045214 sarcomere organization 3.518972e-4
GO:0000296 spermine transport 3.555896e-4
GO:0001889 liver development 3.642446e-4
GO:0010740 positive regulation of intracellular protein kinase cascade 3.682021e-4
GO:0007548 sex differentiation 3.698233e-4
GO:0061008 hepaticobiliary system development 3.705390e-4
GO:0042180 cellular ketone metabolic process 3.708115e-4
GO:0055108 Golgi to transport vesicle transport 3.743006e-4
GO:0001822 kidney development 3.795217e-4
GO:0000002 mitochondrial genome maintenance 3.801037e-4
GO:0060173 limb development 3.815541e-4
GO:0048732 gland development 3.830588e-4
GO:0016049 cell growth 3.830751e-4
GO:0009653 anatomical structure morphogenesis 3.866856e-4
GO:0030278 regulation of ossification 3.878158e-4
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3.984842e-4
GO:0055074 calcium ion homeostasis 4.000454e-4
GO:0006633 fatty acid biosynthetic process 4.023715e-4
GO:0006769 nicotinamide metabolic process 4.052626e-4
GO:0019752 carboxylic acid metabolic process 4.086171e-4
GO:0072507 divalent inorganic cation homeostasis 4.151885e-4
GO:0002456 T cell mediated immunity 4.229781e-4
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 4.299310e-4
GO:0030261 chromosome condensation 4.346052e-4
GO:0046425 regulation of JAK-STAT cascade 4.383251e-4
GO:0033032 regulation of myeloid cell apoptosis 4.450363e-4
GO:0060548 negative regulation of cell death 4.572756e-4
GO:0060538 skeletal muscle organ development 4.591787e-4
GO:0008585 female gonad development 4.591956e-4
GO:0010922 positive regulation of phosphatase activity 4.628651e-4
GO:0021953 central nervous system neuron differentiation 4.675881e-4
GO:0006812 cation transport 4.723393e-4
GO:0060485 mesenchyme development 4.756801e-4
GO:0040011 locomotion 4.931885e-4
GO:0003012 muscle system process 4.939254e-4
GO:0048870 cell motility 4.944650e-4
GO:0046880 regulation of follicle-stimulating hormone secretion 4.947651e-4
GO:0008038 neuron recognition 5.004455e-4
GO:0031323 regulation of cellular metabolic process 5.025862e-4
GO:0009891 positive regulation of biosynthetic process 5.092413e-4
GO:0008284 positive regulation of cell proliferation 5.146286e-4
GO:0042692 muscle cell differentiation 5.165499e-4
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 5.261220e-4
GO:0051707 response to other organism 5.302730e-4
GO:0032733 positive regulation of interleukin-10 production 5.312415e-4
GO:0071236 cellular response to antibiotic 5.438222e-4
GO:0016202 regulation of striated muscle tissue development 5.445376e-4
GO:0016446 somatic hypermutation of immunoglobulin genes 5.477024e-4
GO:0001101 response to acid 5.519355e-4
GO:0070887 cellular response to chemical stimulus 5.704325e-4
GO:0007186 G-protein coupled receptor protein signaling pathway 5.718837e-4
GO:0055008 cardiac muscle tissue morphogenesis 5.721765e-4
GO:0071345 cellular response to cytokine stimulus 5.733898e-4
GO:0001657 ureteric bud development 5.750530e-4
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 5.771428e-4
GO:0016447 somatic recombination of immunoglobulin gene segments 5.820851e-4
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 5.847641e-4
GO:0044036 cell wall macromolecule metabolic process 5.945487e-4
GO:0016043 cellular component organization 6.049178e-4
GO:0014033 neural crest cell differentiation 6.056405e-4
GO:0070093 negative regulation of glucagon secretion 6.098228e-4
GO:0032835 glomerulus development 6.128779e-4
GO:0007292 female gamete generation 6.218317e-4
GO:0061005 cell differentiation involved in kidney development 6.296232e-4
GO:0045358 negative regulation of interferon-beta biosynthetic process 6.319456e-4
GO:0016358 dendrite development 6.406481e-4
GO:0007631 feeding behavior 6.419542e-4
GO:0050774 negative regulation of dendrite morphogenesis 6.438784e-4
GO:0033034 positive regulation of myeloid cell apoptosis 6.438784e-4
GO:0050776 regulation of immune response 6.527996e-4
GO:0006810 transport 6.608080e-4
GO:0002366 leukocyte activation involved in immune response 6.616299e-4
GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway 6.639978e-4
GO:0048520 positive regulation of behavior 6.735987e-4
GO:0010939 regulation of necrotic cell death 6.819290e-4
GO:0042537 benzene-containing compound metabolic process 6.830481e-4
GO:0008611 ether lipid biosynthetic process 6.835320e-4
GO:0032270 positive regulation of cellular protein metabolic process 6.840675e-4
GO:0060412 ventricular septum morphogenesis 6.926296e-4
GO:0007610 behavior 6.931889e-4
GO:0002553 histamine secretion by mast cell 7.087330e-4
GO:0009435 NAD biosynthetic process 7.180531e-4
GO:0051649 establishment of localization in cell 7.307314e-4
GO:0006627 protein processing involved in protein targeting to mitochondrion 7.337192e-4
GO:0060761 negative regulation of response to cytokine stimulus 7.351353e-4
GO:0050671 positive regulation of lymphocyte proliferation 7.412718e-4
GO:0010921 regulation of phosphatase activity 7.445985e-4
GO:0001525 angiogenesis 7.470526e-4
GO:0055070 copper ion homeostasis 7.504394e-4
GO:0090257 regulation of muscle system process 7.524537e-4
GO:0030901 midbrain development 7.607722e-4
GO:0045936 negative regulation of phosphate metabolic process 7.620279e-4
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 7.655634e-4
GO:0035850 epithelial cell differentiation involved in kidney development 7.655634e-4
GO:0030334 regulation of cell migration 7.696007e-4
GO:0032276 regulation of gonadotropin secretion 7.722519e-4
GO:0002682 regulation of immune system process 7.727431e-4
GO:0010466 negative regulation of peptidase activity 7.745971e-4
GO:0048638 regulation of developmental growth 7.851741e-4
GO:0010660 regulation of muscle cell apoptosis 7.856024e-4
GO:0043200 response to amino acid stimulus 8.032718e-4
GO:0007399 nervous system development 8.091502e-4
GO:0060547 negative regulation of necrotic cell death 8.094094e-4
GO:0007267 cell-cell signaling 8.184435e-4
GO:0048285 organelle fission 8.415024e-4
GO:2000021 regulation of ion homeostasis 8.601555e-4
GO:0007176 regulation of epidermal growth factor-activated receptor activity 8.656869e-4
GO:0048644 muscle organ morphogenesis 8.658432e-4
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 8.704342e-4
GO:0045162 clustering of voltage-gated sodium channels 8.914550e-4
GO:0060638 mesenchymal-epithelial cell signaling 9.092296e-4
GO:0007519 skeletal muscle tissue development 9.123526e-4
GO:0045190 isotype switching 9.221837e-4
GO:0051248 negative regulation of protein metabolic process 9.243032e-4
GO:0003183 mitral valve morphogenesis 9.268703e-4
GO:0072111 cell proliferation involved in kidney development 9.290486e-4
GO:0035295 tube development 9.316409e-4
GO:0050864 regulation of B cell activation 9.376491e-4
GO:0003289 atrial septum primum morphogenesis 9.380460e-4
GO:0046634 regulation of alpha-beta T cell activation 9.498865e-4
GO:0000087 M phase of mitotic cell cycle 9.587199e-4
GO:0051247 positive regulation of protein metabolic process 9.664376e-4
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 9.784954e-4
GO:0051795 positive regulation of catagen 9.811940e-4
GO:0043031 negative regulation of macrophage activation 9.928552e-4
GO:0046394 carboxylic acid biosynthetic process 9.940303e-4
GO:0048522 positive regulation of cellular process 9.962207e-4
GO:0007160 cell-matrix adhesion 9.986946e-4
GO:0021860 pyramidal neuron development 1.000428e-3
GO:0051480 cytosolic calcium ion homeostasis 1.001547e-3
GO:0043066 negative regulation of apoptosis 1.009337e-3
GO:0019221 cytokine-mediated signaling pathway 1.020748e-3
GO:0008152 metabolic process 1.039698e-3
GO:0045189 connective tissue growth factor biosynthetic process 1.039795e-3
GO:0043069 negative regulation of programmed cell death 1.044184e-3
GO:0050880 regulation of blood vessel size 1.047492e-3
GO:0072659 protein localization in plasma membrane 1.054900e-3
GO:0045132 meiotic chromosome segregation 1.054900e-3
GO:0042693 muscle cell fate commitment 1.054900e-3
GO:0030279 negative regulation of ossification 1.058281e-3
GO:0010628 positive regulation of gene expression 1.064008e-3
GO:0045665 negative regulation of neuron differentiation 1.071019e-3
GO:0031401 positive regulation of protein modification process 1.084348e-3
GO:0070665 positive regulation of leukocyte proliferation 1.085347e-3
GO:0009607 response to biotic stimulus 1.085530e-3
GO:0008037 cell recognition 1.103706e-3
GO:0070340 detection of bacterial lipopeptide 1.118048e-3
GO:0021700 developmental maturation 1.118256e-3
GO:0021680 cerebellar Purkinje cell layer development 1.129062e-3
GO:0001658 branching involved in ureteric bud morphogenesis 1.134491e-3


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0032501 multicellular organismal process 9.351642e-11
GO:0048856 anatomical structure development 1.037442e-8
GO:0021700 developmental maturation 3.723336e-8
GO:0042759 long-chain fatty acid biosynthetic process 4.418141e-8
GO:0001676 long-chain fatty acid metabolic process 8.955716e-8
GO:0048731 system development 1.405424e-7
GO:0060537 muscle tissue development 1.805210e-7
GO:0032502 developmental process 4.049303e-7
GO:0048469 cell maturation 5.432597e-7
GO:0030203 glycosaminoglycan metabolic process 7.753606e-7
GO:0007275 multicellular organismal development 9.449304e-7
GO:0048240 sperm capacitation 1.010439e-6
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 1.399546e-6
GO:0035051 cardiac cell differentiation 1.722638e-6
GO:0048738 cardiac muscle tissue development 1.947586e-6
GO:0035458 cellular response to interferon-beta 1.979054e-6
GO:0050654 chondroitin sulfate proteoglycan metabolic process 2.334190e-6
GO:0014706 striated muscle tissue development 2.564049e-6
GO:0018149 peptide cross-linking 3.562278e-6
GO:0001568 blood vessel development 4.181830e-6
GO:0022010 central nervous system myelination 4.202100e-6
GO:0032929 negative regulation of superoxide anion generation 4.433240e-6
GO:0006022 aminoglycan metabolic process 5.098925e-6
GO:0030204 chondroitin sulfate metabolic process 5.211195e-6
GO:0045605 negative regulation of epidermal cell differentiation 1.056174e-5
GO:0045844 positive regulation of striated muscle tissue development 1.090058e-5
GO:0055007 cardiac muscle cell differentiation 1.173373e-5
GO:0042060 wound healing 1.212643e-5
GO:0001944 vasculature development 1.391321e-5
GO:0043519 regulation of myosin II filament organization 1.406579e-5
GO:0048013 ephrin receptor signaling pathway 1.627997e-5
GO:0072358 cardiovascular system development 1.644862e-5
GO:0048514 blood vessel morphogenesis 1.739894e-5
GO:0043496 regulation of protein homodimerization activity 1.784116e-5
GO:0030574 collagen catabolic process 1.813923e-5
GO:0042100 B cell proliferation 1.899005e-5
GO:0014003 oligodendrocyte development 1.942088e-5
GO:0008038 neuron recognition 1.995514e-5
GO:0048468 cell development 2.101632e-5
GO:0070167 regulation of biomineral tissue development 2.793576e-5
GO:0002062 chondrocyte differentiation 3.136674e-5
GO:0009611 response to wounding 3.174737e-5
GO:0030500 regulation of bone mineralization 3.235202e-5
GO:2000111 positive regulation of macrophage apoptosis 3.308231e-5
GO:0048643 positive regulation of skeletal muscle tissue development 3.516992e-5
GO:0043473 pigmentation 4.300525e-5
GO:0031424 keratinization 4.387039e-5
GO:0045617 negative regulation of keratinocyte differentiation 5.191858e-5
GO:0050896 response to stimulus 5.355947e-5
GO:0050803 regulation of synapse structure and activity 5.456986e-5
GO:0006029 proteoglycan metabolic process 5.803350e-5
GO:0016198 axon choice point recognition 6.048850e-5
GO:0030318 melanocyte differentiation 7.386169e-5
GO:0048513 organ development 7.421106e-5
GO:0006952 defense response 7.767435e-5
GO:0060025 regulation of synaptic activity 8.039457e-5
GO:2000987 positive regulation of behavioral fear response 8.039457e-5
GO:0003185 sinoatrial valve morphogenesis 8.039457e-5
GO:0035984 cellular response to trichostatin A 8.039457e-5
GO:0003138 primary heart field specification 8.039457e-5
GO:0003006 developmental process involved in reproduction 8.547604e-5
GO:0016553 base conversion or substitution editing 8.716674e-5
GO:0061061 muscle structure development 9.162736e-5
GO:0045683 negative regulation of epidermis development 9.583923e-5
GO:0016554 cytidine to uridine editing 1.021540e-4
GO:0050931 pigment cell differentiation 1.029213e-4
GO:0045666 positive regulation of neuron differentiation 1.046615e-4
GO:0007281 germ cell development 1.069055e-4
GO:0010694 positive regulation of alkaline phosphatase activity 1.081624e-4
GO:0001542 ovulation from ovarian follicle 1.129755e-4
GO:0016043 cellular component organization 1.272422e-4
GO:0051149 positive regulation of muscle cell differentiation 1.277439e-4
GO:0050878 regulation of body fluid levels 1.464534e-4
GO:0048703 embryonic viscerocranium morphogenesis 1.471915e-4
GO:0014898 cardiac muscle hypertrophy in response to stress 1.568653e-4
GO:0030279 negative regulation of ossification 1.721949e-4
GO:0035112 genitalia morphogenesis 1.783798e-4
GO:0001525 angiogenesis 1.793158e-4
GO:0031214 biomineral tissue development 1.804486e-4
GO:0045652 regulation of megakaryocyte differentiation 1.930743e-4
GO:0009888 tissue development 1.943209e-4
GO:2000109 regulation of macrophage apoptosis 1.944547e-4
GO:0045604 regulation of epidermal cell differentiation 1.996314e-4
GO:0031341 regulation of cell killing 2.076198e-4
GO:0001910 regulation of leukocyte mediated cytotoxicity 2.126782e-4
GO:0000245 spliceosome assembly 2.161116e-4
GO:0030278 regulation of ossification 2.170920e-4
GO:0014896 muscle hypertrophy 2.222110e-4
GO:0071840 cellular component organization or biogenesis 2.274789e-4
GO:0051155 positive regulation of striated muscle cell differentiation 2.489418e-4
GO:0010592 positive regulation of lamellipodium assembly 2.560658e-4
GO:0042640 anagen 2.587078e-4
GO:0060035 notochord cell development 2.634635e-4
GO:0042475 odontogenesis of dentine-containing tooth 2.683017e-4
GO:0033364 mast cell secretory granule organization 2.711687e-4
GO:0070189 kynurenine metabolic process 2.878187e-4
GO:0019441 tryptophan catabolic process to kynurenine 2.912703e-4
GO:0008037 cell recognition 3.033666e-4
GO:0071277 cellular response to calcium ion 3.036705e-4
GO:0051146 striated muscle cell differentiation 3.039350e-4
GO:2000727 positive regulation of cardiac muscle cell differentiation 3.166102e-4
GO:2000278 regulation of DNA biosynthetic process 3.199380e-4
GO:0001974 blood vessel remodeling 3.382230e-4
GO:0097117 guanylate kinase-associated protein clustering 3.637698e-4
GO:0097114 N-methyl-D-aspartate receptor clustering 3.637698e-4
GO:0097112 gamma-aminobutyric acid receptor clustering 3.637698e-4
GO:0003151 outflow tract morphogenesis 3.838467e-4
GO:0065008 regulation of biological quality 3.864824e-4
GO:0009653 anatomical structure morphogenesis 3.894692e-4
GO:0021782 glial cell development 3.959702e-4
GO:0010811 positive regulation of cell-substrate adhesion 4.164282e-4
GO:0030719 P granule organization 4.172025e-4
GO:0070166 enamel mineralization 4.172025e-4
GO:0016199 axon midline choice point recognition 4.227123e-4
GO:0010591 regulation of lamellipodium assembly 4.321702e-4
GO:0048066 developmental pigmentation 4.397246e-4
GO:0035058 nonmotile primary cilium assembly 4.499958e-4
GO:0050890 cognition 4.515476e-4
GO:0006968 cellular defense response 4.561140e-4
GO:0046620 regulation of organ growth 4.755763e-4
GO:0014028 notochord formation 4.773045e-4
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 4.773045e-4
GO:0016082 synaptic vesicle priming 4.981750e-4
GO:2000822 regulation of behavioral fear response 5.007704e-4
GO:0033373 maintenance of protease location in mast cell secretory granule 5.521048e-4
GO:0033382 maintenance of granzyme B location in T cell secretory granule 5.521048e-4
GO:0048771 tissue remodeling 5.549643e-4
GO:0048589 developmental growth 5.769608e-4
GO:0006508 proteolysis 6.028225e-4
GO:0048762 mesenchymal cell differentiation 6.079616e-4
GO:0060914 heart formation 6.103947e-4
GO:0007586 digestion 6.114863e-4
GO:0071374 cellular response to parathyroid hormone stimulus 6.166870e-4
GO:0048869 cellular developmental process 6.219284e-4
GO:0060840 artery development 6.346059e-4
GO:0007166 cell surface receptor linked signaling pathway 6.364707e-4
GO:0042692 muscle cell differentiation 6.573022e-4
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 6.719571e-4
GO:0006955 immune response 6.814286e-4
GO:0090073 positive regulation of protein homodimerization activity 6.825333e-4
GO:0007341 penetration of zona pellucida 6.825333e-4
GO:0042476 odontogenesis 6.948505e-4
GO:0035690 cellular response to drug 7.033173e-4
GO:0007269 neurotransmitter secretion 7.358782e-4
GO:0045667 regulation of osteoblast differentiation 8.108142e-4
GO:2001013 epithelial cell proliferation involve in renal tubule morphogenesis 8.318212e-4
GO:0072160 nephron tubule epithelial cell differentiation 8.318212e-4
GO:0050778 positive regulation of immune response 8.643976e-4
GO:0007286 spermatid development 8.853314e-4
GO:0043486 histone exchange 8.871229e-4
GO:0042113 B cell activation 8.890389e-4
GO:0070168 negative regulation of biomineral tissue development 8.897537e-4
GO:0032816 positive regulation of natural killer cell activation 9.646858e-4
GO:0030154 cell differentiation 9.667038e-4
GO:0007499 ectoderm and mesoderm interaction 9.729378e-4
GO:0030220 platelet formation 9.821527e-4
GO:0051239 regulation of multicellular organismal process 9.908448e-4
GO:0006659 phosphatidylserine biosynthetic process 1.004810e-3
GO:0003300 cardiac muscle hypertrophy 1.007180e-3
GO:0060271 cilium morphogenesis 1.020041e-3
GO:0006568 tryptophan metabolic process 1.035199e-3
GO:0035880 embryonic nail plate morphogenesis 1.047261e-3
GO:0044259 multicellular organismal macromolecule metabolic process 1.068018e-3
GO:0008285 negative regulation of cell proliferation 1.082568e-3
GO:0046651 lymphocyte proliferation 1.097135e-3
GO:0034337 RNA folding 1.121115e-3
GO:0032989 cellular component morphogenesis 1.138673e-3
GO:0000902 cell morphogenesis 1.154946e-3
GO:0007616 long-term memory 1.155443e-3
GO:0048610 cellular process involved in reproduction 1.198697e-3
GO:0045597 positive regulation of cell differentiation 1.234775e-3
GO:0001879 detection of yeast 1.238199e-3
GO:0061312 BMP signaling pathway involved in heart development 1.244593e-3
GO:0051795 positive regulation of catagen 1.244593e-3
GO:0048820 hair follicle maturation 1.251375e-3
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1.251375e-3
GO:2000279 negative regulation of DNA biosynthetic process 1.281909e-3
GO:0035050 embryonic heart tube development 1.312174e-3
GO:0031342 negative regulation of cell killing 1.318924e-3
GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 1.328562e-3
GO:0017121 phospholipid scrambling 1.328562e-3
GO:0009913 epidermal cell differentiation 1.342656e-3
GO:0065007 biological regulation 1.352015e-3
GO:0007276 gamete generation 1.352566e-3
GO:0002684 positive regulation of immune system process 1.390113e-3
GO:0033363 secretory granule organization 1.437606e-3
GO:0030510 regulation of BMP signaling pathway 1.437800e-3
GO:0051216 cartilage development 1.439065e-3
GO:0048818 positive regulation of hair follicle maturation 1.441420e-3
GO:0042742 defense response to bacterium 1.447772e-3
GO:0034509 centromeric core chromatin assembly 1.472675e-3
GO:0034080 CenH3-containing nucleosome assembly at centromere 1.472675e-3
GO:0048515 spermatid differentiation 1.474200e-3
GO:0048585 negative regulation of response to stimulus 1.490318e-3
GO:0045682 regulation of epidermis development 1.508198e-3
GO:0019953 sexual reproduction 1.536202e-3
GO:0032943 mononuclear cell proliferation 1.575751e-3
GO:0033762 response to glucagon stimulus 1.576089e-3
GO:0071498 cellular response to fluid shear stress 1.582296e-3
GO:0014888 striated muscle adaptation 1.627155e-3
GO:0048609 multicellular organismal reproductive process 1.654730e-3
GO:2000026 regulation of multicellular organismal development 1.663153e-3
GO:0010106 cellular response to iron ion starvation 1.665420e-3
GO:0006393 termination of mitochondrial transcription 1.665420e-3
GO:0032655 regulation of interleukin-12 production 1.695136e-3
GO:2000725 regulation of cardiac muscle cell differentiation 1.723991e-3
GO:0097118 neuroligin clustering 1.743971e-3
GO:0001501 skeletal system development 1.746861e-3
GO:0032963 collagen metabolic process 1.767380e-3
GO:0048619 embryonic hindgut morphogenesis 1.792611e-3
GO:0030502 negative regulation of bone mineralization 1.793004e-3
GO:0044029 hypomethylation of CpG island 1.824377e-3
GO:0045453 bone resorption 1.824535e-3
GO:0071107 response to parathyroid hormone stimulus 1.877021e-3
GO:0007611 learning or memory 1.899457e-3
GO:0048858 cell projection morphogenesis 1.900614e-3
GO:0046835 carbohydrate phosphorylation 1.933976e-3
GO:0071844 cellular component assembly at cellular level 1.937016e-3
GO:0032252 secretory granule localization 1.970826e-3
GO:0003139 secondary heart field specification 1.970826e-3
GO:0048844 artery morphogenesis 2.003527e-3
GO:0031000 response to caffeine 2.003797e-3
GO:0007521 muscle cell fate determination 2.040306e-3
GO:0090074 negative regulation of protein homodimerization activity 2.052659e-3
GO:0007167 enzyme linked receptor protein signaling pathway 2.073059e-3
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 2.097730e-3
GO:0006666 3-keto-sphinganine metabolic process 2.100980e-3
GO:0060197 cloacal septation 2.122247e-3
GO:0050793 regulation of developmental process 2.124738e-3
GO:0042384 cilium assembly 2.141183e-3
GO:0070373 negative regulation of ERK1 and ERK2 cascade 2.163089e-3
GO:0042634 regulation of hair cycle 2.163485e-3
GO:0022607 cellular component assembly 2.168755e-3
GO:0010886 positive regulation of cholesterol storage 2.178915e-3
GO:0070661 leukocyte proliferation 2.179291e-3
GO:0061039 ovum-producing ovary development 2.179291e-3
GO:0044087 regulation of cellular component biogenesis 2.189013e-3
GO:0046649 lymphocyte activation 2.226102e-3
GO:0003008 system process 2.264677e-3
GO:0001782 B cell homeostasis 2.320947e-3
GO:0030216 keratinocyte differentiation 2.403117e-3
GO:0048709 oligodendrocyte differentiation 2.436234e-3
GO:0006658 phosphatidylserine metabolic process 2.438899e-3
GO:0050789 regulation of biological process 2.446668e-3
GO:0070098 chemokine-mediated signaling pathway 2.506416e-3
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 2.595899e-3
GO:0071842 cellular component organization at cellular level 2.617121e-3
GO:0032814 regulation of natural killer cell activation 2.643277e-3
GO:0048806 genitalia development 2.706123e-3
GO:0043065 positive regulation of apoptosis 2.721139e-3
GO:0046545 development of primary female sexual characteristics 2.764127e-3
GO:0032990 cell part morphogenesis 2.770454e-3
GO:0048485 sympathetic nervous system development 2.806372e-3
GO:0016525 negative regulation of angiogenesis 2.843635e-3
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2.881953e-3
GO:0010033 response to organic substance 2.900442e-3
GO:0051240 positive regulation of multicellular organismal process 2.902522e-3
GO:0043500 muscle adaptation 2.909820e-3
GO:0090287 regulation of cellular response to growth factor stimulus 2.951581e-3
GO:0060536 cartilage morphogenesis 2.988112e-3
GO:0071864 positive regulation of cell proliferation in bone marrow 3.085379e-3
GO:0045019 negative regulation of nitric oxide biosynthetic process 3.180977e-3
GO:0009074 aromatic amino acid family catabolic process 3.287661e-3
GO:0048518 positive regulation of biological process 3.322496e-3
GO:0060986 endocrine hormone secretion 3.354985e-3
GO:0030224 monocyte differentiation 3.413256e-3
GO:0048646 anatomical structure formation involved in morphogenesis 3.431512e-3
GO:0070848 response to growth factor stimulus 3.515228e-3
GO:0031349 positive regulation of defense response 3.569642e-3
GO:0002429 immune response-activating cell surface receptor signaling pathway 3.586047e-3
GO:0071603 endothelial cell-cell adhesion 3.625153e-3
GO:0010232 vascular transport 3.625153e-3
GO:0043049 otic placode formation 3.625153e-3
GO:0006950 response to stress 3.626385e-3
GO:0014033 neural crest cell differentiation 3.640486e-3
GO:0060415 muscle tissue morphogenesis 3.657648e-3
GO:0010634 positive regulation of epithelial cell migration 3.675776e-3
GO:0071695 anatomical structure maturation 3.696728e-3
GO:0050775 positive regulation of dendrite morphogenesis 3.699534e-3
GO:0097116 gephyrin clustering 3.771741e-3
GO:2000821 regulation of grooming behavior 3.771741e-3
GO:2000677 regulation of transcription regulatory region DNA binding 3.798451e-3
GO:0048251 elastic fiber assembly 3.804876e-3
GO:0055012 ventricular cardiac muscle cell differentiation 3.824370e-3
GO:0030282 bone mineralization 3.833286e-3
GO:0042147 retrograde transport, endosome to Golgi 3.863605e-3
GO:0048743 positive regulation of skeletal muscle fiber development 3.894143e-3
GO:0003416 endochondral bone growth 3.894143e-3
GO:0051053 negative regulation of DNA metabolic process 3.908489e-3
GO:0042063 gliogenesis 3.914780e-3
GO:0007599 hemostasis 3.945893e-3
GO:0050795 regulation of behavior 4.019645e-3
GO:0043068 positive regulation of programmed cell death 4.100925e-3
GO:0071841 cellular component organization or biogenesis at cellular level 4.217552e-3
GO:0007062 sister chromatid cohesion 4.268711e-3
GO:0050830 defense response to Gram-positive bacterium 4.292744e-3
GO:0010912 positive regulation of isomerase activity 4.301284e-3
GO:0070349 positive regulation of brown fat cell proliferation 4.301780e-3
GO:0010810 regulation of cell-substrate adhesion 4.307812e-3
GO:0001915 negative regulation of T cell mediated cytotoxicity 4.312838e-3
GO:0035411 catenin import into nucleus 4.351045e-3
GO:0014031 mesenchymal cell development 4.405699e-3
GO:0006953 acute-phase response 4.436357e-3
GO:0010921 regulation of phosphatase activity 4.463758e-3
GO:0090288 negative regulation of cellular response to growth factor stimulus 4.581554e-3
GO:0042269 regulation of natural killer cell mediated cytotoxicity 4.651578e-3
GO:0042221 response to chemical stimulus 4.692868e-3
GO:0060043 regulation of cardiac muscle cell proliferation 4.764747e-3
GO:0007517 muscle organ development 4.770077e-3
GO:0070407 oxidation-dependent protein catabolic process 4.860371e-3
GO:0061042 vascular wound healing 4.860371e-3
GO:0051798 positive regulation of hair follicle development 4.888582e-3
GO:0090322 regulation of superoxide metabolic process 4.913644e-3
GO:0002833 positive regulation of response to biotic stimulus 4.919449e-3
GO:0002757 immune response-activating signal transduction 4.976621e-3
GO:0006954 inflammatory response 5.009901e-3
GO:0043476 pigment accumulation 5.019342e-3
GO:0008585 female gonad development 5.042054e-3
GO:0007507 heart development 5.091858e-3
GO:0044085 cellular component biogenesis 5.096161e-3
GO:0051493 regulation of cytoskeleton organization 5.118591e-3
GO:0070206 protein trimerization 5.121934e-3
GO:0051491 positive regulation of filopodium assembly 5.182292e-3
GO:0010942 positive regulation of cell death 5.324937e-3
GO:0032928 regulation of superoxide anion generation 5.344350e-3
GO:0000003 reproduction 5.354455e-3
GO:0030838 positive regulation of actin filament polymerization 5.371265e-3
GO:0007596 blood coagulation 5.373613e-3
GO:0060297 regulation of sarcomere organization 5.417569e-3
GO:0010922 positive regulation of phosphatase activity 5.437238e-3
GO:0001952 regulation of cell-matrix adhesion 5.495564e-3
GO:0016202 regulation of striated muscle tissue development 5.525878e-3
GO:0016197 endosome transport 5.552261e-3
GO:0003206 cardiac chamber morphogenesis 5.563526e-3
GO:2000831 regulation of steroid hormone secretion 5.583131e-3
GO:0010885 regulation of cholesterol storage 5.626038e-3
GO:0008354 germ cell migration 5.626038e-3
GO:0048644 muscle organ morphogenesis 5.658761e-3
GO:0045746 negative regulation of Notch signaling pathway 5.660771e-3
GO:0051094 positive regulation of developmental process 5.720014e-3
GO:0030514 negative regulation of BMP signaling pathway 5.745884e-3
GO:0003205 cardiac chamber development 5.754330e-3
GO:0030011 maintenance of cell polarity 5.765054e-3
GO:0051172 negative regulation of nitrogen compound metabolic process 5.772253e-3
GO:0002768 immune response-regulating cell surface receptor signaling pathway 5.841580e-3
GO:0048846 axon extension involved in axon guidance 5.856236e-3
GO:0045089 positive regulation of innate immune response 5.885787e-3
GO:0045445 myoblast differentiation 5.894614e-3
GO:0008544 epidermis development 6.011202e-3
GO:0043589 skin morphogenesis 6.081306e-3
GO:0042402 cellular biogenic amine catabolic process 6.160537e-3
GO:0032274 gonadotropin secretion 6.160537e-3
GO:0007413 axonal fasciculation 6.160537e-3
GO:0045321 leukocyte activation 6.180573e-3
GO:0050680 negative regulation of epithelial cell proliferation 6.183838e-3
GO:0030252 growth hormone secretion 6.192972e-3
GO:0006691 leukotriene metabolic process 6.249870e-3
GO:0046660 female sex differentiation 6.276271e-3
GO:0051093 negative regulation of developmental process 6.383011e-3
GO:0009124 nucleoside monophosphate biosynthetic process 6.398647e-3
GO:0060600 dichotomous subdivision of an epithelial terminal unit 6.500026e-3
GO:0030104 water homeostasis 6.500026e-3
GO:0002710 negative regulation of T cell mediated immunity 6.500026e-3
GO:0007267 cell-cell signaling 6.525630e-3
GO:0043480 pigment accumulation in tissues 6.568899e-3
GO:0032023 trypsinogen activation 6.568899e-3
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 6.597661e-3
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 6.656638e-3
GO:0048634 regulation of muscle organ development 6.768255e-3
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 6.851070e-3
GO:0070943 neutrophil mediated killing of symbiont cell 6.862694e-3
GO:0030501 positive regulation of bone mineralization 6.894201e-3
GO:0035295 tube development 6.910746e-3
GO:0007399 nervous system development 6.918493e-3
GO:0046621 negative regulation of organ growth 6.926921e-3
GO:0060395 SMAD protein signal transduction 7.002548e-3
GO:0045663 positive regulation of myoblast differentiation 7.009321e-3
GO:0045892 negative regulation of transcription, DNA-dependent 7.055339e-3
GO:0045668 negative regulation of osteoblast differentiation 7.111356e-3
GO:0044243 multicellular organismal catabolic process 7.133285e-3
GO:0014074 response to purine-containing compound 7.138211e-3
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 7.223760e-3
GO:0072102 glomerulus morphogenesis 7.223760e-3
GO:0048583 regulation of response to stimulus 7.238894e-3
GO:0022414 reproductive process 7.261047e-3
GO:0045616 regulation of keratinocyte differentiation 7.288520e-3
GO:0060485 mesenchyme development 7.387747e-3
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 7.391455e-3
GO:2001054 negative regulation of mesenchymal cell apoptosis 7.559633e-3
GO:0048625 myoblast cell fate commitment 7.608893e-3
GO:0009072 aromatic amino acid family metabolic process 7.654976e-3
GO:0033133 positive regulation of glucokinase activity 7.683505e-3
GO:0030728 ovulation 7.695865e-3
GO:0003007 heart morphogenesis 7.730695e-3
GO:0050851 antigen receptor-mediated signaling pathway 7.766317e-3
GO:0006367 transcription initiation from RNA polymerase II promoter 7.793240e-3
GO:0048745 smooth muscle tissue development 7.819671e-3
GO:0032695 negative regulation of interleukin-12 production 7.862306e-3
GO:0001967 suckling behavior 7.862306e-3
GO:0001887 selenium compound metabolic process 7.911974e-3
GO:0070169 positive regulation of biomineral tissue development 7.913110e-3
GO:0060244 negative regulation of cell proliferation involved in contact inhibition 7.944216e-3
GO:0032231 regulation of actin filament bundle assembly 7.983012e-3
GO:0035850 epithelial cell differentiation involved in kidney development 8.010138e-3
GO:0042127 regulation of cell proliferation 8.013112e-3
GO:0002839 positive regulation of immune response to tumor cell 8.035969e-3
GO:0009914 hormone transport 8.209169e-3
GO:0008593 regulation of Notch signaling pathway 8.217861e-3
GO:0002820 negative regulation of adaptive immune response 8.303827e-3
GO:0003208 cardiac ventricle morphogenesis 8.325916e-3
GO:0030538 embryonic genitalia morphogenesis 8.427950e-3
GO:0060134 prepulse inhibition 8.489695e-3
GO:0051883 killing of cells in other organism involved in symbiotic interaction 8.489695e-3
GO:0050776 regulation of immune response 8.497807e-3
GO:0007268 synaptic transmission 8.648215e-3
GO:0001964 startle response 8.655760e-3
GO:0045669 positive regulation of osteoblast differentiation 8.705108e-3
GO:0006376 mRNA splice site selection 8.728287e-3
GO:0048584 positive regulation of response to stimulus 8.738507e-3
GO:0048320 axial mesoderm formation 8.760065e-3
GO:0002837 regulation of immune response to tumor cell 8.843145e-3
GO:0031640 killing of cells of other organism 8.987460e-3
GO:0051253 negative regulation of RNA metabolic process 9.060602e-3
GO:0085029 extracellular matrix assembly 9.068357e-3
GO:0000301 retrograde transport, vesicle recycling within Golgi 9.068357e-3
GO:0048333 mesodermal cell differentiation 9.129703e-3
GO:0010884 positive regulation of lipid storage 9.129703e-3
GO:0030857 negative regulation of epithelial cell differentiation 9.395505e-3
GO:0007442 hindgut morphogenesis 9.395505e-3
GO:0002764 immune response-regulating signaling pathway 9.415041e-3
GO:0002707 negative regulation of lymphocyte mediated immunity 9.449088e-3
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway 9.500840e-3
GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching 9.500840e-3
GO:0071236 cellular response to antibiotic 9.507638e-3
GO:0042984 regulation of amyloid precursor protein biosynthetic process 9.582559e-3
GO:0001954 positive regulation of cell-matrix adhesion 9.783873e-3
GO:0010629 negative regulation of gene expression 9.954427e-3
GO:0042832 defense response to protozoan 1.005088e-2
GO:0007519 skeletal muscle tissue development 1.010812e-2
GO:0042554 superoxide anion generation 1.017845e-2
GO:0055021 regulation of cardiac muscle tissue growth 1.030920e-2
GO:0034755 iron ion transmembrane transport 1.054823e-2
GO:0019370 leukotriene biosynthetic process 1.064951e-2
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 1.071972e-2
GO:0010744 positive regulation of macrophage derived foam cell differentiation 1.078552e-2
GO:0002200 somatic diversification of immune receptors 1.078774e-2
GO:0050807 regulation of synapse organization 1.093105e-2
GO:0009968 negative regulation of signal transduction 1.120957e-2
GO:0070869 heterochromatin formation involved in chromatin silencing 1.124283e-2
GO:0009992 cellular water homeostasis 1.124283e-2
GO:0071559 response to transforming growth factor beta stimulus 1.125587e-2
GO:0071625 vocalization behavior 1.128874e-2
GO:0051937 catecholamine transport 1.130874e-2
GO:0048633 positive regulation of skeletal muscle tissue growth 1.132891e-2
GO:0035129 post-embryonic hindlimb morphogenesis 1.132891e-2
GO:0006426 glycyl-tRNA aminoacylation 1.132891e-2
GO:0010743 regulation of macrophage derived foam cell differentiation 1.136189e-2
GO:0030865 cortical cytoskeleton organization 1.146893e-2
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 1.169598e-2
GO:0006072 glycerol-3-phosphate metabolic process 1.179394e-2
GO:0015867 ATP transport 1.179394e-2
GO:0030888 regulation of B cell proliferation 1.211047e-2
GO:0040011 locomotion 1.221811e-2
GO:0048729 tissue morphogenesis 1.227598e-2
GO:0006003 fructose 2,6-bisphosphate metabolic process 1.229303e-2
GO:0032956 regulation of actin cytoskeleton organization 1.235953e-2
GO:0055008 cardiac muscle tissue morphogenesis 1.242418e-2
GO:0006357 regulation of transcription from RNA polymerase II promoter 1.254562e-2
GO:0002456 T cell mediated immunity 1.273372e-2
GO:0043620 regulation of DNA-dependent transcription in response to stress 1.273372e-2
GO:0031343 positive regulation of cell killing 1.285359e-2
GO:0015986 ATP synthesis coupled proton transport 1.287301e-2
GO:0071320 cellular response to cAMP 1.287419e-2
GO:0032825 positive regulation of natural killer cell differentiation 1.292504e-2
GO:0022618 ribonucleoprotein complex assembly 1.306800e-2
GO:0001505 regulation of neurotransmitter levels 1.315307e-2
GO:0006419 alanyl-tRNA aminoacylation 1.317760e-2
GO:0016560 protein import into peroxisome matrix, docking 1.317760e-2
GO:0048343 paraxial mesodermal cell fate commitment 1.317760e-2
GO:0009051 pentose-phosphate shunt, oxidative branch 1.317760e-2
GO:0044236 multicellular organismal metabolic process 1.320860e-2
GO:0032861 activation of Rap GTPase activity 1.322039e-2
GO:0034109 homotypic cell-cell adhesion 1.330131e-2
GO:0007059 chromosome segregation 1.335555e-2
GO:0001937 negative regulation of endothelial cell proliferation 1.337224e-2
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 1.343949e-2
GO:0040019 positive regulation of embryonic development 1.343949e-2
GO:0044344 cellular response to fibroblast growth factor stimulus 1.370358e-2
GO:0048608 reproductive structure development 1.382811e-2
GO:0046879 hormone secretion 1.405042e-2
GO:0008090 retrograde axon cargo transport 1.424069e-2
GO:0015938 coenzyme A catabolic process 1.428578e-2
GO:0022008 neurogenesis 1.428675e-2
GO:0045778 positive regulation of ossification 1.432857e-2
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 1.432963e-2
GO:2000833 positive regulation of steroid hormone secretion 1.434185e-2
GO:0060513 prostatic bud formation 1.434185e-2
GO:0001755 neural crest cell migration 1.450586e-2
GO:0001736 establishment of planar polarity 1.455441e-2
GO:0048520 positive regulation of behavior 1.461272e-2