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Novel motif:79

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name:motif79_ACATCTACAA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0050896 response to stimulus 1.068932e-17
GO:0014866 skeletal myofibril assembly 4.843161e-17
GO:0048747 muscle fiber development 1.714987e-16
GO:0048856 anatomical structure development 2.665631e-16
GO:0010038 response to metal ion 2.960143e-16
GO:0055002 striated muscle cell development 4.830660e-16
GO:0030261 chromosome condensation 6.538789e-16
GO:0055001 muscle cell development 7.884028e-16
GO:0032502 developmental process 1.297763e-15
GO:0030241 skeletal muscle myosin thick filament assembly 2.467896e-15
GO:0031032 actomyosin structure organization 2.548240e-15
GO:0051592 response to calcium ion 3.631857e-15
GO:0010035 response to inorganic substance 5.083206e-15
GO:0032501 multicellular organismal process 1.708367e-14
GO:0030239 myofibril assembly 2.041734e-14
GO:0051641 cellular localization 2.964637e-14
GO:0072358 cardiovascular system development 6.936258e-14
GO:0002576 platelet degranulation 7.200670e-14
GO:0051234 establishment of localization 7.738135e-14
GO:0034621 cellular macromolecular complex subunit organization 1.057453e-13
GO:0048739 cardiac muscle fiber development 1.379095e-13
GO:0048646 anatomical structure formation involved in morphogenesis 1.666846e-13
GO:0009888 tissue development 1.723754e-13
GO:0009653 anatomical structure morphogenesis 1.819948e-13
GO:0002694 regulation of leukocyte activation 2.329990e-13
GO:0018149 peptide cross-linking 3.116179e-13
GO:0006323 DNA packaging 4.764179e-13
GO:0006928 cellular component movement 8.801718e-13
GO:0051649 establishment of localization in cell 1.015141e-12
GO:0007275 multicellular organismal development 1.023434e-12
GO:0030240 skeletal muscle thin filament assembly 1.491601e-12
GO:0051179 localization 1.601125e-12
GO:0006996 organelle organization 1.827331e-12
GO:0050865 regulation of cell activation 2.969141e-12
GO:0006810 transport 3.170049e-12
GO:0042060 wound healing 3.576186e-12
GO:0030168 platelet activation 3.930830e-12
GO:0034622 cellular macromolecular complex assembly 4.100082e-12
GO:0032764 negative regulation of mast cell cytokine production 5.312722e-12
GO:0042692 muscle cell differentiation 8.535503e-12
GO:0048731 system development 1.025693e-11
GO:0030299 intestinal cholesterol absorption 1.132302e-11
GO:0001775 cell activation 1.231241e-11
GO:0043623 cellular protein complex assembly 1.400866e-11
GO:0022600 digestive system process 1.605261e-11
GO:0048513 organ development 1.698658e-11
GO:0071103 DNA conformation change 2.045950e-11
GO:0007076 mitotic chromosome condensation 2.312205e-11
GO:0050794 regulation of cellular process 3.341002e-11
GO:0071844 cellular component assembly at cellular level 3.863521e-11
GO:0030029 actin filament-based process 4.144456e-11
GO:0032940 secretion by cell 4.213840e-11
GO:0051146 striated muscle cell differentiation 4.356343e-11
GO:0001101 response to acid 4.680650e-11
GO:0065008 regulation of biological quality 4.872402e-11
GO:0002376 immune system process 5.045312e-11
GO:0061061 muscle structure development 5.325728e-11
GO:0071842 cellular component organization at cellular level 7.000223e-11
GO:0030048 actin filament-based movement 7.612150e-11
GO:0046903 secretion 7.750301e-11
GO:0050892 intestinal absorption 9.453952e-11
GO:0070252 actin-mediated cell contraction 9.589901e-11
GO:0010927 cellular component assembly involved in morphogenesis 1.012868e-10
GO:0009611 response to wounding 1.031175e-10
GO:0003008 system process 1.093592e-10
GO:0002682 regulation of immune system process 1.300713e-10
GO:0007586 digestion 1.379713e-10
GO:0065007 biological regulation 1.573227e-10
GO:0006788 heme oxidation 2.341776e-10
GO:0071363 cellular response to growth factor stimulus 2.643287e-10
GO:0006940 regulation of smooth muscle contraction 2.972227e-10
GO:0045214 sarcomere organization 3.259448e-10
GO:0030049 muscle filament sliding 4.009494e-10
GO:0050789 regulation of biological process 4.051155e-10
GO:0071841 cellular component organization or biogenesis at cellular level 4.256155e-10
GO:0048769 sarcomerogenesis 6.076204e-10
GO:0010838 positive regulation of keratinocyte proliferation 6.319870e-10
GO:0061033 secretion by lung epithelial cell involved in lung growth 6.319870e-10
GO:0030036 actin cytoskeleton organization 6.435128e-10
GO:0071230 cellular response to amino acid stimulus 8.976172e-10
GO:0055003 cardiac myofibril assembly 9.226216e-10
GO:0014806 smooth muscle hyperplasia 1.133818e-9
GO:0050867 positive regulation of cell activation 1.354800e-9
GO:0071229 cellular response to acid 1.434663e-9
GO:0031295 T cell costimulation 1.860101e-9
GO:0002696 positive regulation of leukocyte activation 1.969521e-9
GO:0051249 regulation of lymphocyte activation 1.974129e-9
GO:0003012 muscle system process 2.315403e-9
GO:0043500 muscle adaptation 2.419035e-9
GO:0048584 positive regulation of response to stimulus 2.471892e-9
GO:0045766 positive regulation of angiogenesis 3.554228e-9
GO:0055013 cardiac muscle cell development 3.875920e-9
GO:0050776 regulation of immune response 4.691333e-9
GO:0050878 regulation of body fluid levels 7.374140e-9
GO:0071417 cellular response to organic nitrogen 8.133042e-9
GO:0071840 cellular component organization or biogenesis 9.033354e-9
GO:0007507 heart development 1.039529e-8
GO:0071418 cellular response to amine stimulus 1.069475e-8
GO:0000819 sister chromatid segregation 1.156787e-8
GO:0006950 response to stress 1.221952e-8
GO:0043200 response to amino acid stimulus 1.276830e-8
GO:0000070 mitotic sister chromatid segregation 1.287594e-8
GO:0032763 regulation of mast cell cytokine production 1.394711e-8
GO:0009605 response to external stimulus 1.897057e-8
GO:0007015 actin filament organization 1.914210e-8
GO:0051251 positive regulation of lymphocyte activation 3.331324e-8
GO:0032989 cellular component morphogenesis 3.415360e-8
GO:0048661 positive regulation of smooth muscle cell proliferation 4.114783e-8
GO:0010667 negative regulation of cardiac muscle cell apoptosis 4.294336e-8
GO:0048518 positive regulation of biological process 4.813429e-8
GO:0035051 cardiac cell differentiation 4.816724e-8
GO:0001568 blood vessel development 5.158805e-8
GO:0016043 cellular component organization 5.178376e-8
GO:0061088 regulation of sequestering of zinc ion 5.586398e-8
GO:0044241 lipid digestion 6.794853e-8
GO:0032103 positive regulation of response to external stimulus 6.876578e-8
GO:0050851 antigen receptor-mediated signaling pathway 7.023978e-8
GO:0007010 cytoskeleton organization 7.574910e-8
GO:0048583 regulation of response to stimulus 7.820219e-8
GO:0032964 collagen biosynthetic process 9.327432e-8
GO:0051272 positive regulation of cellular component movement 9.762714e-8
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 9.797032e-8
GO:0002429 immune response-activating cell surface receptor signaling pathway 9.856337e-8
GO:0001944 vasculature development 1.034119e-7
GO:0002684 positive regulation of immune system process 1.086213e-7
GO:0002768 immune response-regulating cell surface receptor signaling pathway 1.242673e-7
GO:0005983 starch catabolic process 1.258631e-7
GO:0048468 cell development 1.265874e-7
GO:0007596 blood coagulation 1.326883e-7
GO:0007165 signal transduction 1.439244e-7
GO:0048738 cardiac muscle tissue development 1.442831e-7
GO:0030199 collagen fibril organization 1.471402e-7
GO:0043305 negative regulation of mast cell degranulation 1.487281e-7
GO:0007599 hemostasis 1.535832e-7
GO:0060537 muscle tissue development 1.622523e-7
GO:0051716 cellular response to stimulus 1.666811e-7
GO:0030335 positive regulation of cell migration 1.762764e-7
GO:0050864 regulation of B cell activation 1.791794e-7
GO:0031296 B cell costimulation 1.806782e-7
GO:0046660 female sex differentiation 1.815836e-7
GO:0040017 positive regulation of locomotion 1.902592e-7
GO:0030890 positive regulation of B cell proliferation 1.931230e-7
GO:0002548 monocyte chemotaxis 1.954016e-7
GO:0043503 skeletal muscle fiber adaptation 2.222006e-7
GO:0044036 cell wall macromolecule metabolic process 2.308870e-7
GO:0014706 striated muscle tissue development 2.324086e-7
GO:0045663 positive regulation of myoblast differentiation 2.360925e-7
GO:0030154 cell differentiation 2.511954e-7
GO:0040011 locomotion 2.526915e-7
GO:0048520 positive regulation of behavior 2.771654e-7
GO:2000147 positive regulation of cell motility 2.960542e-7
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 2.976656e-7
GO:0042167 heme catabolic process 3.100066e-7
GO:0048869 cellular developmental process 3.940219e-7
GO:0045765 regulation of angiogenesis 4.034345e-7
GO:0070848 response to growth factor stimulus 4.106111e-7
GO:0043550 regulation of lipid kinase activity 4.335143e-7
GO:0002920 regulation of humoral immune response 4.366693e-7
GO:0055007 cardiac muscle cell differentiation 4.980259e-7
GO:0046545 development of primary female sexual characteristics 5.545450e-7
GO:0022607 cellular component assembly 5.584790e-7
GO:0071157 negative regulation of cell cycle arrest 5.725089e-7
GO:0033007 negative regulation of mast cell activation involved in immune response 6.016493e-7
GO:0060437 lung growth 6.095850e-7
GO:0010664 negative regulation of striated muscle cell apoptosis 6.783067e-7
GO:0006887 exocytosis 6.837846e-7
GO:0034394 protein localization at cell surface 7.011681e-7
GO:0046824 positive regulation of nucleocytoplasmic transport 7.013030e-7
GO:0032388 positive regulation of intracellular transport 7.044394e-7
GO:0006458 'de novo' protein folding 7.160248e-7
GO:0016998 cell wall macromolecule catabolic process 7.335292e-7
GO:0006955 immune response 7.843287e-7
GO:0009306 protein secretion 9.007865e-7
GO:0044085 cellular component biogenesis 1.058549e-6
GO:0048870 cell motility 1.078366e-6
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1.084432e-6
GO:0006936 muscle contraction 1.176514e-6
GO:0032963 collagen metabolic process 1.199444e-6
GO:0014075 response to amine stimulus 1.217289e-6
GO:0090316 positive regulation of intracellular protein transport 1.342930e-6
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.441658e-6
GO:0030888 regulation of B cell proliferation 1.455236e-6
GO:0044259 multicellular organismal macromolecule metabolic process 1.468837e-6
GO:0007207 activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway 1.513149e-6
GO:0044236 multicellular organismal metabolic process 1.541578e-6
GO:0009991 response to extracellular stimulus 1.548047e-6
GO:0061153 trachea gland development 1.603046e-6
GO:0071577 zinc ion transmembrane transport 1.775511e-6
GO:0051084 'de novo' posttranslational protein folding 1.864257e-6
GO:0071294 cellular response to zinc ion 1.886058e-6
GO:0042221 response to chemical stimulus 1.909410e-6
GO:0002757 immune response-activating signal transduction 1.919437e-6
GO:0002885 positive regulation of hypersensitivity 1.963658e-6
GO:0050863 regulation of T cell activation 2.052668e-6
GO:0002764 immune response-regulating signaling pathway 2.232696e-6
GO:0001525 angiogenesis 2.374316e-6
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 2.457060e-6
GO:0006644 phospholipid metabolic process 2.532981e-6
GO:0006434 seryl-tRNA aminoacylation 2.587653e-6
GO:0035924 cellular response to vascular endothelial growth factor stimulus 2.753799e-6
GO:0048263 determination of dorsal identity 2.768552e-6
GO:0022002 negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway 2.768552e-6
GO:0006333 chromatin assembly or disassembly 2.788754e-6
GO:0048522 positive regulation of cellular process 2.917491e-6
GO:0060541 respiratory system development 3.148853e-6
GO:0006629 lipid metabolic process 3.156535e-6
GO:0007517 muscle organ development 3.208223e-6
GO:0007162 negative regulation of cell adhesion 3.283008e-6
GO:0031667 response to nutrient levels 3.510186e-6
GO:0014805 smooth muscle adaptation 3.514262e-6
GO:0001935 endothelial cell proliferation 3.534448e-6
GO:0002683 negative regulation of immune system process 3.599967e-6
GO:0055069 zinc ion homeostasis 3.769442e-6
GO:0006069 ethanol oxidation 3.839551e-6
GO:0002719 negative regulation of cytokine production involved in immune response 3.992276e-6
GO:0043392 negative regulation of DNA binding 4.195405e-6
GO:0051222 positive regulation of protein transport 4.221944e-6
GO:0006941 striated muscle contraction 4.286033e-6
GO:0065009 regulation of molecular function 4.373271e-6
GO:0051098 regulation of binding 4.699174e-6
GO:0050871 positive regulation of B cell activation 4.737261e-6
GO:0002820 negative regulation of adaptive immune response 5.031056e-6
GO:0010665 regulation of cardiac muscle cell apoptosis 5.040103e-6
GO:0051149 positive regulation of muscle cell differentiation 5.107708e-6
GO:0008610 lipid biosynthetic process 5.109664e-6
GO:0090218 positive regulation of lipid kinase activity 5.172103e-6
GO:0021881 Wnt receptor signaling pathway involved in forebrain neuron fate commitment 5.174451e-6
GO:0016192 vesicle-mediated transport 5.496976e-6
GO:0043549 regulation of kinase activity 6.039143e-6
GO:0031099 regeneration 6.092418e-6
GO:0048514 blood vessel morphogenesis 6.165900e-6
GO:0050777 negative regulation of immune response 6.499560e-6
GO:0007154 cell communication 6.547454e-6
GO:0048262 determination of dorsal/ventral asymmetry 6.636656e-6
GO:0033036 macromolecule localization 6.826568e-6
GO:0023052 signaling 7.217555e-6
GO:0045023 G0 to G1 transition 7.834508e-6
GO:0008284 positive regulation of cell proliferation 7.889669e-6
GO:0007166 cell surface receptor linked signaling pathway 8.167054e-6
GO:0000902 cell morphogenesis 8.288300e-6
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 8.914444e-6
GO:0060548 negative regulation of cell death 8.973273e-6
GO:0016477 cell migration 9.554751e-6
GO:0048872 homeostasis of number of cells 1.010873e-5
GO:0010243 response to organic nitrogen 1.017754e-5
GO:0010559 regulation of glycoprotein biosynthetic process 1.030278e-5
GO:0043933 macromolecular complex subunit organization 1.060900e-5
GO:0048762 mesenchymal cell differentiation 1.073566e-5
GO:0048878 chemical homeostasis 1.129185e-5
GO:0010656 negative regulation of muscle cell apoptosis 1.184287e-5
GO:0002883 regulation of hypersensitivity 1.258114e-5
GO:0065003 macromolecular complex assembly 1.377095e-5
GO:0051346 negative regulation of hydrolase activity 1.478004e-5
GO:0048016 inositol phosphate-mediated signaling 1.498786e-5
GO:0033004 negative regulation of mast cell activation 1.517739e-5
GO:0051276 chromosome organization 1.576646e-5
GO:0019637 organophosphate metabolic process 1.602568e-5
GO:0002634 regulation of germinal center formation 1.637829e-5
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 1.664864e-5
GO:0051258 protein polymerization 1.672546e-5
GO:0034764 positive regulation of transmembrane transport 1.710699e-5
GO:0044255 cellular lipid metabolic process 1.767532e-5
GO:0008283 cell proliferation 1.786645e-5
GO:0007292 female gamete generation 1.906836e-5
GO:0035295 tube development 1.928081e-5
GO:0051094 positive regulation of developmental process 1.932478e-5
GO:0006959 humoral immune response 1.949103e-5
GO:0006349 regulation of gene expression by genetic imprinting 2.026031e-5
GO:0050793 regulation of developmental process 2.032513e-5
GO:0042307 positive regulation of protein import into nucleus 2.074796e-5
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 2.082768e-5
GO:0022603 regulation of anatomical structure morphogenesis 2.119463e-5
GO:0051024 positive regulation of immunoglobulin secretion 2.124223e-5
GO:0002697 regulation of immune effector process 2.156395e-5
GO:0051338 regulation of transferase activity 2.163945e-5
GO:0060693 regulation of branching involved in salivary gland morphogenesis 2.167611e-5
GO:0050900 leukocyte migration 2.201357e-5
GO:0050870 positive regulation of T cell activation 2.319057e-5
GO:2000679 positive regulation of transcription regulatory region DNA binding 2.424505e-5
GO:0007213 muscarinic acetylcholine receptor signaling pathway 2.448625e-5
GO:0009615 response to virus 2.697043e-5
GO:0006650 glycerophospholipid metabolic process 2.705128e-5
GO:0007059 chromosome segregation 2.746557e-5
GO:0048285 organelle fission 2.843046e-5
GO:0030540 female genitalia development 2.889417e-5
GO:0010662 regulation of striated muscle cell apoptosis 2.988601e-5
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 3.070671e-5
GO:0001817 regulation of cytokine production 3.136742e-5
GO:0019538 protein metabolic process 3.256450e-5
GO:0046854 phosphatidylinositol phosphorylation 3.279110e-5
GO:0060059 embryonic retina morphogenesis in camera-type eye 3.308060e-5
GO:0061039 ovum-producing ovary development 3.353877e-5
GO:0007067 mitosis 3.368108e-5
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 3.406332e-5
GO:0014033 neural crest cell differentiation 3.536846e-5
GO:0097022 lymphocyte migration into lymph node 3.663448e-5
GO:0030301 cholesterol transport 3.771667e-5
GO:0001776 leukocyte homeostasis 3.774383e-5
GO:0014031 mesenchymal cell development 3.916514e-5
GO:0050790 regulation of catalytic activity 3.962241e-5
GO:0008104 protein localization 4.001117e-5
GO:0071514 genetic imprinting 4.144802e-5
GO:0043069 negative regulation of programmed cell death 4.171652e-5
GO:0002577 regulation of antigen processing and presentation 4.398641e-5
GO:0032848 negative regulation of cellular pH reduction 4.414564e-5
GO:0043375 CD8-positive, alpha-beta T cell lineage commitment 4.414564e-5
GO:0021747 cochlear nucleus development 4.414564e-5
GO:0014042 positive regulation of neuron maturation 4.414564e-5
GO:0034613 cellular protein localization 4.473911e-5
GO:0034720 histone H3-K4 demethylation 4.489520e-5
GO:0072610 interleukin-12 secretion 4.603528e-5
GO:0000114 regulation of transcription involved in G1 phase of mitotic cell cycle 4.603528e-5
GO:0002408 myeloid dendritic cell chemotaxis 4.603528e-5
GO:0000087 M phase of mitotic cell cycle 4.708019e-5
GO:0043129 surfactant homeostasis 4.793324e-5
GO:0002260 lymphocyte homeostasis 4.852117e-5
GO:0033561 regulation of water loss via skin 4.861356e-5
GO:2000107 negative regulation of leukocyte apoptosis 4.920543e-5
GO:0006937 regulation of muscle contraction 4.972543e-5
GO:0060897 neural plate regionalization 5.009603e-5
GO:0008206 bile acid metabolic process 5.129488e-5
GO:0034154 toll-like receptor 7 signaling pathway 5.214218e-5
GO:0031444 slow-twitch skeletal muscle fiber contraction 5.242345e-5
GO:0070727 cellular macromolecule localization 5.276947e-5
GO:0009887 organ morphogenesis 5.312807e-5
GO:0008654 phospholipid biosynthetic process 5.340334e-5
GO:0051239 regulation of multicellular organismal process 5.442332e-5
GO:0042592 homeostatic process 5.500841e-5
GO:0030449 regulation of complement activation 5.516641e-5
GO:0050921 positive regulation of chemotaxis 5.526737e-5
GO:0070271 protein complex biogenesis 5.527125e-5
GO:0043066 negative regulation of apoptosis 5.583250e-5
GO:0010837 regulation of keratinocyte proliferation 5.584913e-5
GO:0002253 activation of immune response 5.704898e-5
GO:0050853 B cell receptor signaling pathway 5.772900e-5
GO:0045738 negative regulation of DNA repair 5.810586e-5
GO:0055080 cation homeostasis 5.859533e-5
GO:0022602 ovulation cycle process 5.909441e-5
GO:0010810 regulation of cell-substrate adhesion 6.000558e-5
GO:0003007 heart morphogenesis 6.011796e-5
GO:0002703 regulation of leukocyte mediated immunity 6.188550e-5
GO:0030155 regulation of cell adhesion 6.240877e-5
GO:0048729 tissue morphogenesis 6.295556e-5
GO:2000008 regulation of protein localization at cell surface 6.543122e-5
GO:0060638 mesenchymal-epithelial cell signaling 6.569709e-5
GO:0051187 cofactor catabolic process 6.596439e-5
GO:0031497 chromatin assembly 6.715208e-5
GO:0002040 sprouting angiogenesis 6.787246e-5
GO:0006952 defense response 7.121238e-5
GO:0003219 cardiac right ventricle formation 7.483791e-5
GO:0050801 ion homeostasis 7.523955e-5
GO:0050707 regulation of cytokine secretion 7.558646e-5
GO:0006829 zinc ion transport 7.581758e-5
GO:0043501 skeletal muscle adaptation 7.594219e-5
GO:0051640 organelle localization 7.594332e-5
GO:0015918 sterol transport 7.606741e-5
GO:0010466 negative regulation of peptidase activity 7.623946e-5
GO:0006461 protein complex assembly 7.664605e-5
GO:0030324 lung development 7.706261e-5
GO:0043017 positive regulation of lymphotoxin A biosynthetic process 7.742104e-5
GO:0009893 positive regulation of metabolic process 7.782061e-5
GO:0002886 regulation of myeloid leukocyte mediated immunity 7.796258e-5
GO:0007005 mitochondrion organization 7.834377e-5
GO:0060485 mesenchyme development 7.894350e-5
GO:0002695 negative regulation of leukocyte activation 7.917765e-5
GO:0045859 regulation of protein kinase activity 8.059235e-5
GO:0001782 B cell homeostasis 8.090763e-5
GO:0034762 regulation of transmembrane transport 8.115778e-5
GO:0042596 fear response 8.165291e-5
GO:0051100 negative regulation of binding 8.228365e-5
GO:0051101 regulation of DNA binding 8.324791e-5
GO:0043301 negative regulation of leukocyte degranulation 8.459213e-5
GO:0006808 regulation of nitrogen utilization 8.570968e-5
GO:0042100 B cell proliferation 8.585125e-5
GO:0021999 neural plate anterior/posterior regionalization 9.052262e-5
GO:0032714 negative regulation of interleukin-5 production 9.052262e-5
GO:0050795 regulation of behavior 9.104399e-5
GO:2000021 regulation of ion homeostasis 9.168712e-5
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 9.411726e-5
GO:0032185 septin cytoskeleton organization 9.466949e-5
GO:0045869 negative regulation of retroviral genome replication 9.499423e-5
GO:0060662 salivary gland cavitation 9.602506e-5
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 9.650980e-5
GO:0051303 establishment of chromosome localization 9.675808e-5
GO:0048644 muscle organ morphogenesis 9.740993e-5
GO:0030091 protein repair 1.002170e-4
GO:0009584 detection of visible light 1.012502e-4
GO:0001654 eye development 1.014360e-4
GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly 1.018652e-4
GO:0045073 regulation of chemokine biosynthetic process 1.023947e-4
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1.048113e-4
GO:0071822 protein complex subunit organization 1.051793e-4
GO:0045080 positive regulation of chemokine biosynthetic process 1.078199e-4
GO:0042698 ovulation cycle 1.102338e-4
GO:0032696 negative regulation of interleukin-13 production 1.123489e-4
GO:0002699 positive regulation of immune effector process 1.146319e-4
GO:0048010 vascular endothelial growth factor receptor signaling pathway 1.149044e-4
GO:0050891 multicellular organismal water homeostasis 1.162530e-4
GO:0030003 cellular cation homeostasis 1.175068e-4
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 1.204369e-4
GO:0048742 regulation of skeletal muscle fiber development 1.224811e-4
GO:0010746 regulation of plasma membrane long-chain fatty acid transport 1.225498e-4
GO:0051656 establishment of organelle localization 1.235272e-4
GO:0071453 cellular response to oxygen levels 1.240478e-4
GO:0006325 chromatin organization 1.251244e-4
GO:0050778 positive regulation of immune response 1.268436e-4
GO:0021680 cerebellar Purkinje cell layer development 1.270564e-4
GO:0042157 lipoprotein metabolic process 1.275731e-4
GO:0051961 negative regulation of nervous system development 1.281824e-4
GO:0031669 cellular response to nutrient levels 1.296220e-4
GO:0048634 regulation of muscle organ development 1.328923e-4
GO:0002675 positive regulation of acute inflammatory response 1.332389e-4
GO:0009583 detection of light stimulus 1.354037e-4
GO:0034633 retinol transport 1.357787e-4
GO:0070613 regulation of protein processing 1.372977e-4
GO:0042127 regulation of cell proliferation 1.380124e-4
GO:0001970 positive regulation of activation of membrane attack complex 1.415311e-4
GO:0048592 eye morphogenesis 1.419808e-4
GO:0007584 response to nutrient 1.421837e-4
GO:0032642 regulation of chemokine production 1.438515e-4
GO:0008585 female gonad development 1.469521e-4
GO:0030323 respiratory tube development 1.473461e-4
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 1.507182e-4
GO:0010043 response to zinc ion 1.511162e-4
GO:0090257 regulation of muscle system process 1.535191e-4
GO:0071276 cellular response to cadmium ion 1.535641e-4
GO:0030854 positive regulation of granulocyte differentiation 1.542790e-4
GO:0060415 muscle tissue morphogenesis 1.557416e-4
GO:0021678 third ventricle development 1.558026e-4
GO:0008588 release of cytoplasmic sequestered NF-kappaB 1.599081e-4
GO:0051549 positive regulation of keratinocyte migration 1.599081e-4
GO:0032990 cell part morphogenesis 1.602627e-4
GO:0034728 nucleosome organization 1.610497e-4
GO:0007186 G-protein coupled receptor protein signaling pathway 1.615861e-4
GO:0009855 determination of bilateral symmetry 1.668530e-4
GO:0008543 fibroblast growth factor receptor signaling pathway 1.682589e-4
GO:0043589 skin morphogenesis 1.693557e-4
GO:0001542 ovulation from ovarian follicle 1.733705e-4
GO:0006656 phosphatidylcholine biosynthetic process 1.736386e-4
GO:0002819 regulation of adaptive immune response 1.795170e-4
GO:0032847 regulation of cellular pH reduction 1.799039e-4
GO:0085029 extracellular matrix assembly 1.818151e-4
GO:0002698 negative regulation of immune effector process 1.856405e-4
GO:0040030 regulation of molecular function, epigenetic 1.867969e-4
GO:0045575 basophil activation 1.867969e-4
GO:0001694 histamine biosynthetic process 1.867969e-4
GO:0050670 regulation of lymphocyte proliferation 1.873270e-4
GO:0003266 regulation of secondary heart field cardioblast proliferation 1.885440e-4
GO:0019933 cAMP-mediated signaling 1.910827e-4
GO:0031060 regulation of histone methylation 1.917495e-4
GO:0032101 regulation of response to external stimulus 1.934679e-4
GO:0007399 nervous system development 1.938032e-4
GO:0042993 positive regulation of transcription factor import into nucleus 1.961573e-4
GO:0009987 cellular process 2.017989e-4
GO:0009799 specification of symmetry 2.019931e-4
GO:0044092 negative regulation of molecular function 2.030227e-4
GO:0050920 regulation of chemotaxis 2.032536e-4
GO:0014888 striated muscle adaptation 2.038834e-4
GO:0001503 ossification 2.081926e-4
GO:0048660 regulation of smooth muscle cell proliferation 2.087551e-4
GO:0048251 elastic fiber assembly 2.123650e-4
GO:0050663 cytokine secretion 2.128514e-4
GO:0043206 fibril organization 2.144739e-4
GO:0045909 positive regulation of vasodilation 2.249007e-4
GO:0048858 cell projection morphogenesis 2.261006e-4
GO:0003211 cardiac ventricle formation 2.262907e-4
GO:0046668 regulation of retinal cell programmed cell death 2.302161e-4
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.366409e-4
GO:0051336 regulation of hydrolase activity 2.408466e-4
GO:0035094 response to nicotine 2.441934e-4
GO:0061307 cardiac neural crest cell differentiation involved in heart development 2.499436e-4
GO:0022408 negative regulation of cell-cell adhesion 2.537535e-4
GO:0006911 phagocytosis, engulfment 2.544437e-4
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 2.635921e-4
GO:0007094 mitotic cell cycle spindle assembly checkpoint 2.647265e-4
GO:0009060 aerobic respiration 2.662762e-4
GO:0048741 skeletal muscle fiber development 2.683984e-4
GO:0000056 ribosomal small subunit export from nucleus 2.747683e-4
GO:0001957 intramembranous ossification 2.771693e-4
GO:0030279 negative regulation of ossification 2.784465e-4
GO:0010574 regulation of vascular endothelial growth factor production 2.823546e-4
GO:2000191 regulation of fatty acid transport 2.857311e-4
GO:0055008 cardiac muscle tissue morphogenesis 2.876231e-4
GO:0043030 regulation of macrophage activation 2.884463e-4
GO:0002604 regulation of dendritic cell antigen processing and presentation 2.916828e-4
GO:0035265 organ growth 3.094212e-4
GO:0030334 regulation of cell migration 3.178096e-4
GO:0010604 positive regulation of macromolecule metabolic process 3.178941e-4
GO:0051569 regulation of histone H3-K4 methylation 3.262317e-4
GO:0002673 regulation of acute inflammatory response 3.264046e-4
GO:0071173 spindle assembly checkpoint 3.276429e-4
GO:0032944 regulation of mononuclear cell proliferation 3.314429e-4
GO:0006873 cellular ion homeostasis 3.334416e-4
GO:0033689 negative regulation of osteoblast proliferation 3.413453e-4
GO:0071174 mitotic cell cycle spindle checkpoint 3.417210e-4
GO:0019079 viral genome replication 3.436185e-4
GO:0002921 negative regulation of humoral immune response 3.484509e-4
GO:0043461 proton-transporting ATP synthase complex assembly 3.524589e-4
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 3.528784e-4
GO:0060343 trabecula formation 3.555024e-4


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0032849 positive regulation of cellular pH reduction 1.482120e-13
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 2.385015e-12
GO:0022417 protein maturation by protein folding 2.385015e-12
GO:0015670 carbon dioxide transport 3.374646e-12
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 1.714133e-11
GO:0009268 response to pH 2.117889e-10
GO:0032847 regulation of cellular pH reduction 3.489943e-10
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 4.331429e-10
GO:0006022 aminoglycan metabolic process 2.891326e-9
GO:0048844 artery morphogenesis 8.056061e-9
GO:0032501 multicellular organismal process 8.586549e-9
GO:0030157 pancreatic juice secretion 1.003288e-8
GO:0045844 positive regulation of striated muscle tissue development 1.113738e-8
GO:0048743 positive regulation of skeletal muscle fiber development 1.338205e-8
GO:0010957 negative regulation of vitamin D biosynthetic process 2.597905e-8
GO:0007586 digestion 3.411696e-8
GO:0048643 positive regulation of skeletal muscle tissue development 4.211556e-8
GO:0034337 RNA folding 4.766216e-8
GO:0006707 cholesterol catabolic process 4.766216e-8
GO:0030203 glycosaminoglycan metabolic process 4.857900e-8
GO:0060840 artery development 5.276916e-8
GO:0050654 chondroitin sulfate proteoglycan metabolic process 1.005273e-7
GO:0007517 muscle organ development 1.050950e-7
GO:0035909 aorta morphogenesis 1.131977e-7
GO:0044029 hypomethylation of CpG island 1.260105e-7
GO:0030204 chondroitin sulfate metabolic process 1.271321e-7
GO:0050896 response to stimulus 1.829521e-7
GO:0042036 negative regulation of cytokine biosynthetic process 2.124300e-7
GO:0035904 aorta development 2.829222e-7
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 3.627276e-7
GO:0009201 ribonucleoside triphosphate biosynthetic process 4.628654e-7
GO:0001974 blood vessel remodeling 5.016538e-7
GO:2000279 negative regulation of DNA biosynthetic process 5.450959e-7
GO:0006754 ATP biosynthetic process 6.087043e-7
GO:0010894 negative regulation of steroid biosynthetic process 7.658390e-7
GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport 9.069400e-7
GO:0034103 regulation of tissue remodeling 9.486580e-7
GO:0009145 purine nucleoside triphosphate biosynthetic process 9.869916e-7
GO:0006631 fatty acid metabolic process 9.952494e-7
GO:0009142 nucleoside triphosphate biosynthetic process 1.004090e-6
GO:0045780 positive regulation of bone resorption 1.034957e-6
GO:0032787 monocarboxylic acid metabolic process 1.169238e-6
GO:0034105 positive regulation of tissue remodeling 1.325603e-6
GO:0006029 proteoglycan metabolic process 1.414265e-6
GO:0009887 organ morphogenesis 1.456268e-6
GO:0018149 peptide cross-linking 1.618931e-6
GO:0051234 establishment of localization 1.894803e-6
GO:0006633 fatty acid biosynthetic process 1.999727e-6
GO:0022600 digestive system process 2.266861e-6
GO:0006810 transport 3.113588e-6
GO:0048513 organ development 3.447169e-6
GO:0048856 anatomical structure development 3.554757e-6
GO:0019408 dolichol biosynthetic process 3.862695e-6
GO:0008152 metabolic process 4.267742e-6
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 4.739735e-6
GO:0003008 system process 4.926648e-6
GO:0006706 steroid catabolic process 5.145582e-6
GO:0015860 purine nucleoside transport 5.413637e-6
GO:0045124 regulation of bone resorption 6.589648e-6
GO:0060986 endocrine hormone secretion 6.801982e-6
GO:0044255 cellular lipid metabolic process 8.145596e-6
GO:0002328 pro-B cell differentiation 8.241680e-6
GO:0042221 response to chemical stimulus 8.797218e-6
GO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation 9.405158e-6
GO:0035910 ascending aorta morphogenesis 9.405158e-6
GO:0072530 purine-containing compound transmembrane transport 9.755206e-6
GO:0045751 negative regulation of Toll signaling pathway 9.909561e-6
GO:0090288 negative regulation of cellular response to growth factor stimulus 1.262215e-5
GO:0040019 positive regulation of embryonic development 1.442549e-5
GO:0032274 gonadotropin secretion 1.446212e-5
GO:0009152 purine ribonucleotide biosynthetic process 1.463609e-5
GO:0045746 negative regulation of Notch signaling pathway 1.822435e-5
GO:0019348 dolichol metabolic process 1.918009e-5
GO:0015669 gas transport 1.948680e-5
GO:0046850 regulation of bone remodeling 2.003946e-5
GO:0009653 anatomical structure morphogenesis 2.020615e-5
GO:0070563 negative regulation of vitamin D receptor signaling pathway 2.145121e-5
GO:2000647 negative regulation of stem cell proliferation 2.145121e-5
GO:0042851 L-alanine metabolic process 2.145121e-5
GO:0035921 desmosome disassembly 2.145121e-5
GO:0010839 negative regulation of keratinocyte proliferation 2.145121e-5
GO:0042180 cellular ketone metabolic process 2.404872e-5
GO:0006082 organic acid metabolic process 2.613981e-5
GO:0019752 carboxylic acid metabolic process 2.723696e-5
GO:0005976 polysaccharide metabolic process 2.943916e-5
GO:0046314 phosphocreatine biosynthetic process 3.174969e-5
GO:2000758 positive regulation of peptidyl-lysine acetylation 3.339962e-5
GO:0045670 regulation of osteoclast differentiation 4.250582e-5
GO:0048641 regulation of skeletal muscle tissue development 4.661769e-5
GO:0045672 positive regulation of osteoclast differentiation 5.387608e-5
GO:2000278 regulation of DNA biosynthetic process 5.578184e-5
GO:0045081 negative regulation of interleukin-10 biosynthetic process 5.786398e-5
GO:0046514 ceramide catabolic process 5.804136e-5
GO:0021522 spinal cord motor neuron differentiation 5.845564e-5
GO:0048742 regulation of skeletal muscle fiber development 5.924505e-5
GO:0048731 system development 6.362497e-5
GO:0042759 long-chain fatty acid biosynthetic process 6.415637e-5
GO:0045409 negative regulation of interleukin-6 biosynthetic process 6.570298e-5
GO:0042752 regulation of circadian rhythm 6.850607e-5
GO:0035108 limb morphogenesis 7.113755e-5
GO:0044030 regulation of DNA methylation 7.149463e-5
GO:0045128 negative regulation of reciprocal meiotic recombination 7.197055e-5
GO:0006311 meiotic gene conversion 7.197055e-5
GO:0006467 protein thiol-disulfide exchange 7.406349e-5
GO:0003209 cardiac atrium morphogenesis 8.002573e-5
GO:0006198 cAMP catabolic process 8.175749e-5
GO:0060556 regulation of vitamin D biosynthetic process 8.975403e-5
GO:0043048 dolichyl monophosphate biosynthetic process 9.533180e-5
GO:0070562 regulation of vitamin D receptor signaling pathway 9.601479e-5
GO:0016525 negative regulation of angiogenesis 9.656429e-5
GO:0051561 elevation of mitochondrial calcium ion concentration 9.811207e-5
GO:0007275 multicellular organismal development 9.886445e-5
GO:0048771 tissue remodeling 9.930685e-5
GO:0048729 tissue morphogenesis 9.956435e-5
GO:0060173 limb development 1.007029e-4
GO:0006629 lipid metabolic process 1.017470e-4
GO:0009260 ribonucleotide biosynthetic process 1.047916e-4
GO:0045835 negative regulation of meiosis 1.065922e-4
GO:0009888 tissue development 1.168034e-4
GO:0002344 B cell affinity maturation 1.181853e-4
GO:0032502 developmental process 1.240651e-4
GO:0035964 COPI-coated vesicle budding 1.262080e-4
GO:0060972 left/right pattern formation 1.415391e-4
GO:0002339 B cell selection 1.415391e-4
GO:0046826 negative regulation of protein export from nucleus 1.489618e-4
GO:0044238 primary metabolic process 1.579090e-4
GO:0032846 positive regulation of homeostatic process 1.652960e-4
GO:0009308 amine metabolic process 1.676953e-4
GO:0021515 cell differentiation in spinal cord 1.678769e-4
GO:0050906 detection of stimulus involved in sensory perception 1.726473e-4
GO:0008593 regulation of Notch signaling pathway 1.746061e-4
GO:0007155 cell adhesion 1.813545e-4
GO:0045814 negative regulation of gene expression, epigenetic 1.944798e-4
GO:0022610 biological adhesion 1.987933e-4
GO:0051640 organelle localization 2.027280e-4
GO:0031953 negative regulation of protein autophosphorylation 2.111728e-4
GO:0051093 negative regulation of developmental process 2.155390e-4
GO:0010288 response to lead ion 2.164167e-4
GO:0046394 carboxylic acid biosynthetic process 2.233750e-4
GO:0070585 protein localization in mitochondrion 2.285545e-4
GO:0045595 regulation of cell differentiation 2.672655e-4
GO:0015858 nucleoside transport 2.725411e-4
GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process 2.811375e-4
GO:0060806 negative regulation of cell differentiation involved in embryonic placenta development 2.811375e-4
GO:2000756 regulation of peptidyl-lysine acetylation 3.067674e-4
GO:0007608 sensory perception of smell 3.072045e-4
GO:0003289 atrial septum primum morphogenesis 3.110119e-4
GO:0072001 renal system development 3.196261e-4
GO:0003230 cardiac atrium development 3.238859e-4
GO:0051659 maintenance of mitochondrion location 3.333915e-4
GO:0007519 skeletal muscle tissue development 3.374743e-4
GO:0001655 urogenital system development 3.416232e-4
GO:0048704 embryonic skeletal system morphogenesis 3.554586e-4
GO:0070869 heterochromatin formation involved in chromatin silencing 3.590334e-4
GO:0072274 metanephric glomerular basement membrane development 3.682670e-4
GO:0072249 metanephric glomerular visceral epithelial cell development 3.682670e-4
GO:0048677 axon extension involved in regeneration 3.682670e-4
GO:0051646 mitochondrion localization 3.737823e-4
GO:0021510 spinal cord development 3.764555e-4
GO:0034374 low-density lipoprotein particle remodeling 3.846459e-4
GO:0044242 cellular lipid catabolic process 4.050385e-4
GO:0007165 signal transduction 4.055100e-4
GO:0030330 DNA damage response, signal transduction by p53 class mediator 4.112304e-4
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 4.127881e-4
GO:0048644 muscle organ morphogenesis 4.309469e-4
GO:0010817 regulation of hormone levels 4.463810e-4
GO:0001501 skeletal system development 4.569191e-4
GO:0016576 histone dephosphorylation 4.663460e-4
GO:0048343 paraxial mesodermal cell fate commitment 4.670187e-4
GO:0014049 positive regulation of glutamate secretion 4.696465e-4
GO:0032728 positive regulation of interferon-beta production 4.779499e-4
GO:0060538 skeletal muscle organ development 4.798575e-4
GO:0051155 positive regulation of striated muscle cell differentiation 4.894357e-4
GO:0051657 maintenance of organelle location 4.944602e-4
GO:0044283 small molecule biosynthetic process 5.269441e-4
GO:0051149 positive regulation of muscle cell differentiation 5.280000e-4
GO:0016042 lipid catabolic process 5.320631e-4
GO:0044281 small molecule metabolic process 5.402147e-4
GO:0007589 body fluid secretion 5.452889e-4
GO:0060631 regulation of meiosis I 5.531604e-4
GO:0010033 response to organic substance 5.584922e-4
GO:0060563 neuroepithelial cell differentiation 5.587896e-4
GO:0050886 endocrine process 5.814647e-4
GO:0009395 phospholipid catabolic process 5.816108e-4
GO:0009914 hormone transport 6.151462e-4
GO:0048311 mitochondrion distribution 6.202203e-4
GO:0001822 kidney development 6.246987e-4
GO:0007606 sensory perception of chemical stimulus 6.349849e-4
GO:0046879 hormone secretion 6.452172e-4
GO:0060537 muscle tissue development 6.725867e-4
GO:0046466 membrane lipid catabolic process 6.798241e-4
GO:0021516 dorsal spinal cord development 6.798241e-4
GO:0007229 integrin-mediated signaling pathway 6.938463e-4
GO:0044237 cellular metabolic process 6.980904e-4
GO:0032321 positive regulation of Rho GTPase activity 7.091326e-4
GO:0046689 response to mercury ion 7.149310e-4
GO:0002064 epithelial cell development 7.187418e-4
GO:0006643 membrane lipid metabolic process 7.217259e-4
GO:0009214 cyclic nucleotide catabolic process 7.222931e-4
GO:0010042 response to manganese ion 7.302208e-4
GO:0048199 vesicle targeting, to, from or within Golgi 7.659187e-4
GO:0035786 protein complex oligomerization 7.745937e-4
GO:0002009 morphogenesis of an epithelium 8.196456e-4
GO:0001736 establishment of planar polarity 8.818097e-4
GO:0044241 lipid digestion 8.860336e-4
GO:0042249 establishment of planar polarity of embryonic epithelium 8.995623e-4
GO:0010232 vascular transport 9.468155e-4
GO:0021782 glial cell development 1.006830e-3
GO:0045187 regulation of circadian sleep/wake cycle, sleep 1.027409e-3
GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration 1.032289e-3
GO:0080134 regulation of response to stress 1.042806e-3
GO:0048512 circadian behavior 1.056145e-3
GO:0050711 negative regulation of interleukin-1 secretion 1.060819e-3
GO:0035295 tube development 1.069613e-3
GO:0042769 DNA damage response, detection of DNA damage 1.073724e-3
GO:0010043 response to zinc ion 1.101244e-3
GO:0001516 prostaglandin biosynthetic process 1.108459e-3
GO:0051239 regulation of multicellular organismal process 1.144025e-3
GO:0006665 sphingolipid metabolic process 1.150608e-3
GO:0003357 noradrenergic neuron differentiation 1.159892e-3
GO:0032692 negative regulation of interleukin-1 production 1.187431e-3
GO:0051179 localization 1.193466e-3
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing 1.203548e-3
GO:0015867 ATP transport 1.203548e-3
GO:0015868 purine ribonucleotide transport 1.205342e-3
GO:0018209 peptidyl-serine modification 1.209780e-3
GO:0048539 bone marrow development 1.271645e-3
GO:0060312 regulation of blood vessel remodeling 1.271645e-3
GO:0010520 regulation of reciprocal meiotic recombination 1.271645e-3
GO:0060413 atrial septum morphogenesis 1.273089e-3
GO:0001967 suckling behavior 1.273089e-3
GO:0060426 lung vasculature development 1.302537e-3
GO:0023052 signaling 1.314747e-3
GO:0042060 wound healing 1.339624e-3
GO:0030149 sphingolipid catabolic process 1.349757e-3
GO:0016090 prenol metabolic process 1.365338e-3
GO:0010038 response to metal ion 1.366766e-3
GO:0000710 meiotic mismatch repair 1.387044e-3
GO:0061061 muscle structure development 1.420273e-3
GO:0006603 phosphocreatine metabolic process 1.432646e-3
GO:0046903 secretion 1.466502e-3
GO:0040020 regulation of meiosis 1.490250e-3
GO:0006705 mineralocorticoid biosynthetic process 1.497904e-3
GO:2000026 regulation of multicellular organismal development 1.517374e-3
GO:0044243 multicellular organismal catabolic process 1.544836e-3
GO:0007164 establishment of tissue polarity 1.571575e-3
GO:0046549 retinal cone cell development 1.577874e-3
GO:0051147 regulation of muscle cell differentiation 1.678552e-3
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1.682986e-3
GO:0003183 mitral valve morphogenesis 1.682986e-3
GO:0045989 positive regulation of striated muscle contraction 1.707647e-3
GO:0010519 negative regulation of phospholipase activity 1.730715e-3
GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry 1.737129e-3
GO:0046034 ATP metabolic process 1.775305e-3
GO:0001710 mesodermal cell fate commitment 1.780136e-3
GO:0001676 long-chain fatty acid metabolic process 1.795406e-3
GO:0022010 central nervous system myelination 1.808275e-3
GO:0032808 lacrimal gland development 1.860595e-3
GO:0060415 muscle tissue morphogenesis 1.898238e-3
GO:0000132 establishment of mitotic spindle orientation 1.926703e-3
GO:0045596 negative regulation of cell differentiation 1.927064e-3
GO:0002763 positive regulation of myeloid leukocyte differentiation 1.942882e-3
GO:0032025 response to cobalt ion 1.950171e-3
GO:0045637 regulation of myeloid cell differentiation 2.033056e-3
GO:0060338 regulation of type I interferon-mediated signaling pathway 2.043356e-3
GO:0051096 positive regulation of helicase activity 2.043533e-3
GO:0015893 drug transport 2.082243e-3
GO:0010350 cellular response to magnesium starvation 2.088251e-3
GO:0001503 ossification 2.112694e-3
GO:0006626 protein targeting to mitochondrion 2.134841e-3
GO:0031016 pancreas development 2.150351e-3
GO:0030263 apoptotic chromosome condensation 2.186688e-3
GO:0001913 T cell mediated cytotoxicity 2.186688e-3
GO:0072560 type B pancreatic cell maturation 2.231738e-3
GO:0009987 cellular process 2.243497e-3
GO:0051173 positive regulation of nitrogen compound metabolic process 2.289334e-3
GO:0042632 cholesterol homeostasis 2.329870e-3
GO:0042745 circadian sleep/wake cycle 2.330499e-3
GO:0006693 prostaglandin metabolic process 2.330499e-3
GO:0046541 saliva secretion 2.382417e-3
GO:0002761 regulation of myeloid leukocyte differentiation 2.409078e-3
GO:0007166 cell surface receptor linked signaling pathway 2.436736e-3
GO:0043570 maintenance of DNA repeat elements 2.440235e-3
GO:0072655 establishment of protein localization in mitochondrion 2.443531e-3
GO:0048333 mesodermal cell differentiation 2.464477e-3
GO:0007154 cell communication 2.468136e-3
GO:0060021 palate development 2.523864e-3
GO:0051445 regulation of meiotic cell cycle 2.539154e-3
GO:0031529 ruffle organization 2.573077e-3
GO:0030900 forebrain development 2.603899e-3
GO:0043009 chordate embryonic development 2.614174e-3
GO:0051224 negative regulation of protein transport 2.626780e-3
GO:0009790 embryo development 2.650069e-3
GO:0040001 establishment of mitotic spindle localization 2.666597e-3
GO:0060429 epithelium development 2.705804e-3
GO:0006851 mitochondrial calcium ion transport 2.724234e-3
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2.734102e-3
GO:0050793 regulation of developmental process 2.771234e-3
GO:0071383 cellular response to steroid hormone stimulus 2.789924e-3
GO:0010720 positive regulation of cell development 2.884110e-3
GO:0015939 pantothenate metabolic process 2.903923e-3
GO:0009125 nucleoside monophosphate catabolic process 2.913926e-3
GO:0042396 phosphagen biosynthetic process 2.947915e-3
GO:0021520 spinal cord motor neuron cell fate specification 2.949028e-3
GO:0051153 regulation of striated muscle cell differentiation 2.952617e-3
GO:0042938 dipeptide transport 3.011978e-3
GO:0007622 rhythmic behavior 3.069576e-3
GO:2001021 negative regulation of response to DNA damage stimulus 3.074464e-3
GO:0072331 signal transduction by p53 class mediator 3.115773e-3
GO:0032648 regulation of interferon-beta production 3.118279e-3
GO:0045639 positive regulation of myeloid cell differentiation 3.120352e-3
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 3.180424e-3
GO:0050974 detection of mechanical stimulus involved in sensory perception 3.204871e-3
GO:0014706 striated muscle tissue development 3.234480e-3
GO:0009225 nucleotide-sugar metabolic process 3.259367e-3
GO:0051606 detection of stimulus 3.317693e-3
GO:0060632 regulation of microtubule-based movement 3.353123e-3
GO:0060414 aorta smooth muscle tissue morphogenesis 3.353123e-3
GO:0042770 signal transduction in response to DNA damage 3.362689e-3
GO:0016925 protein sumoylation 3.398851e-3
GO:0051094 positive regulation of developmental process 3.404077e-3
GO:0048935 peripheral nervous system neuron development 3.414662e-3
GO:0014045 establishment of endothelial blood-brain barrier 3.486921e-3
GO:0061028 establishment of endothelial barrier 3.545744e-3
GO:0031018 endocrine pancreas development 3.561780e-3
GO:0051095 regulation of helicase activity 3.583744e-3
GO:0009611 response to wounding 3.586714e-3
GO:0046825 regulation of protein export from nucleus 3.594992e-3
GO:0070206 protein trimerization 3.613790e-3
GO:0021517 ventral spinal cord development 3.662948e-3
GO:0007156 homophilic cell adhesion 3.782530e-3
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 3.782746e-3
GO:0022410 circadian sleep/wake cycle process 3.845702e-3
GO:0014009 glial cell proliferation 3.850710e-3
GO:0072422 signal transduction involved in DNA damage checkpoint 4.020032e-3
GO:0021796 cerebral cortex regionalization 4.047544e-3
GO:0042891 antibiotic transport 4.075590e-3
GO:0032231 regulation of actin filament bundle assembly 4.084111e-3
GO:0045932 negative regulation of muscle contraction 4.376765e-3
GO:0051036 regulation of endosome size 4.488663e-3
GO:0035582 negative regulation of BMP signaling pathway by extracellular sequestering of BMP 4.488663e-3
GO:0019428 allantoin biosynthetic process 4.488663e-3
GO:0006790 sulfur compound metabolic process 4.553799e-3
GO:0045597 positive regulation of cell differentiation 4.619381e-3
GO:0048665 neuron fate specification 4.771642e-3
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 4.791721e-3
GO:0009792 embryo development ending in birth or egg hatching 4.896956e-3
GO:0051053 negative regulation of DNA metabolic process 4.929717e-3
GO:0006164 purine nucleotide biosynthetic process 4.939361e-3
GO:0001937 negative regulation of endothelial cell proliferation 4.998687e-3
GO:0007417 central nervous system development 5.009419e-3
GO:0048514 blood vessel morphogenesis 5.149140e-3
GO:0023061 signal release 5.185213e-3
GO:0090317 negative regulation of intracellular protein transport 5.234476e-3
GO:0090076 relaxation of skeletal muscle 5.235382e-3
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 5.235382e-3
GO:0043313 regulation of neutrophil degranulation 5.235382e-3
GO:0006301 postreplication repair 5.356838e-3
GO:0051293 establishment of spindle localization 5.374701e-3
GO:0070541 response to platinum ion 5.399536e-3
GO:0045039 protein import into mitochondrial inner membrane 5.424019e-3
GO:0010001 glial cell differentiation 5.448531e-3
GO:0002827 positive regulation of T-helper 1 type immune response 5.448650e-3
GO:0009628 response to abiotic stimulus 5.500346e-3
GO:0009267 cellular response to starvation 5.513013e-3
GO:0042448 progesterone metabolic process 5.650390e-3
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 5.650390e-3
GO:0009100 glycoprotein metabolic process 5.673216e-3
GO:0060795 cell fate commitment involved in formation of primary germ layers 5.704240e-3
GO:0046381 CMP-N-acetylneuraminate metabolic process 5.803598e-3
GO:0060577 pulmonary vein morphogenesis 5.847581e-3
GO:0006030 chitin metabolic process 5.878281e-3
GO:0001561 fatty acid alpha-oxidation 5.878281e-3
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 5.890897e-3
GO:0032481 positive regulation of type I interferon production 5.908485e-3
GO:0007076 mitotic chromosome condensation 6.038212e-3
GO:0002577 regulation of antigen processing and presentation 6.068044e-3
GO:0032319 regulation of Rho GTPase activity 6.126577e-3
GO:0032094 response to food 6.258173e-3
GO:0046415 urate metabolic process 6.302262e-3
GO:0045408 regulation of interleukin-6 biosynthetic process 6.302262e-3
GO:0046456 icosanoid biosynthetic process 6.323107e-3
GO:0045214 sarcomere organization 6.330377e-3
GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine 6.418064e-3
GO:0001542 ovulation from ovarian follicle 6.435247e-3
GO:0031573 intra-S DNA damage checkpoint 6.592650e-3
GO:0005975 carbohydrate metabolic process 6.700819e-3
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 6.745700e-3
GO:0048518 positive regulation of biological process 6.759314e-3
GO:0045671 negative regulation of osteoclast differentiation 6.831060e-3
GO:0045074 regulation of interleukin-10 biosynthetic process 6.889874e-3
GO:0048386 positive regulation of retinoic acid receptor signaling pathway 6.910537e-3
GO:0060174 limb bud formation 6.922655e-3
GO:0035023 regulation of Rho protein signal transduction 6.956953e-3
GO:0006839 mitochondrial transport 6.963175e-3
GO:0034113 heterotypic cell-cell adhesion 6.994973e-3
GO:0003323 type B pancreatic cell development 7.079324e-3
GO:0014034 neural crest cell fate commitment 7.114542e-3
GO:0050982 detection of mechanical stimulus 7.189862e-3
GO:0034605 cellular response to heat 7.228152e-3
GO:0001837 epithelial to mesenchymal transition 7.312670e-3
GO:0034097 response to cytokine stimulus 7.356069e-3
GO:0010447 response to acidity 7.369539e-3
GO:0035239 tube morphogenesis 7.541286e-3
GO:0007512 adult heart development 7.552775e-3
GO:0001708 cell fate specification 7.576100e-3
GO:0031328 positive regulation of cellular biosynthetic process 7.611683e-3
GO:0003170 heart valve development 7.788008e-3
GO:0006357 regulation of transcription from RNA polymerase II promoter 7.811897e-3
GO:0003007 heart morphogenesis 7.867625e-3
GO:0030177 positive regulation of Wnt receptor signaling pathway 7.890945e-3
GO:0055114 oxidation-reduction process 7.947333e-3
GO:0048710 regulation of astrocyte differentiation 7.953871e-3
GO:0090141 positive regulation of mitochondrial fission 7.956857e-3
GO:0000114 regulation of transcription involved in G1 phase of mitotic cell cycle 7.956857e-3
GO:0060578 superior vena cava morphogenesis 7.956857e-3
GO:0001738 morphogenesis of a polarized epithelium 8.088642e-3
GO:0010628 positive regulation of gene expression 8.185511e-3
GO:0016446 somatic hypermutation of immunoglobulin genes 8.436103e-3
GO:0071333 cellular response to glucose stimulus 8.580163e-3
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 8.580857e-3
GO:0060284 regulation of cell development 8.730891e-3
GO:0006457 protein folding 8.772848e-3
GO:0060525 prostate glandular acinus development 8.978426e-3
GO:0014063 negative regulation of serotonin secretion 8.979387e-3
GO:0048642 negative regulation of skeletal muscle tissue development 8.985874e-3
GO:0045988 negative regulation of striated muscle contraction 9.122935e-3
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 9.123339e-3
GO:0045722 positive regulation of gluconeogenesis 9.123339e-3
GO:0003341 cilium movement 9.155997e-3
GO:0030299 intestinal cholesterol absorption 9.159136e-3
GO:0003283 atrial septum development 9.218643e-3
GO:0006636 unsaturated fatty acid biosynthetic process 9.325205e-3
GO:0010524 positive regulation of calcium ion transport into cytosol 9.353000e-3
GO:0090140 regulation of mitochondrial fission 9.719090e-3
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 9.719090e-3
GO:0007399 nervous system development 9.732018e-3
GO:0051051 negative regulation of transport 9.754443e-3
GO:0035270 endocrine system development 9.756721e-3
GO:0051656 establishment of organelle localization 9.851457e-3
GO:0001946 lymphangiogenesis 9.928029e-3
GO:0048598 embryonic morphogenesis 1.013542e-2
GO:0030001 metal ion transport 1.015561e-2
GO:0008207 C21-steroid hormone metabolic process 1.024564e-2
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 1.025101e-2
GO:0007501 mesodermal cell fate specification 1.025101e-2
GO:0060296 regulation of cilium beat frequency involved in ciliary motility 1.031961e-2
GO:0010815 bradykinin catabolic process 1.031961e-2
GO:0001678 cellular glucose homeostasis 1.035789e-2
GO:0030031 cell projection assembly 1.039724e-2
GO:0060562 epithelial tube morphogenesis 1.050755e-2
GO:0032107 regulation of response to nutrient levels 1.073665e-2
GO:0001778 plasma membrane repair 1.074451e-2
GO:0046069 cGMP catabolic process 1.074451e-2
GO:0055085 transmembrane transport 1.081706e-2
GO:0060285 ciliary cell motility 1.089507e-2
GO:0010963 regulation of L-arginine import 1.089507e-2
GO:0008610 lipid biosynthetic process 1.090150e-2
GO:0051716 cellular response to stimulus 1.093183e-2
GO:0009056 catabolic process 1.106262e-2
GO:0030252 growth hormone secretion 1.116445e-2
GO:0016337 cell-cell adhesion 1.126979e-2
GO:0051602 response to electrical stimulus 1.149942e-2
GO:0032479 regulation of type I interferon production 1.161978e-2
GO:0032026 response to magnesium ion 1.174879e-2
GO:0043403 skeletal muscle tissue regeneration 1.177010e-2
GO:0034474 U2 snRNA 3'-end processing 1.177378e-2
GO:0090241 negative regulation of histone H4 acetylation 1.177378e-2
GO:0034401 regulation of transcription by chromatin organization 1.177378e-2
GO:0060809 mesodermal to mesenchymal transition involved in gastrulation 1.193093e-2
GO:0043420 anthranilate metabolic process 1.193093e-2
GO:0034516 response to vitamin B6 1.193093e-2
GO:0030522 intracellular receptor mediated signaling pathway 1.202900e-2
GO:0035264 multicellular organism growth 1.206926e-2
GO:0051567 histone H3-K9 methylation 1.218307e-2
GO:0001547 antral ovarian follicle growth 1.218307e-2
GO:0010738 regulation of protein kinase A signaling cascade 1.221342e-2
GO:0046847 filopodium assembly 1.238885e-2
GO:0045541 negative regulation of cholesterol biosynthetic process 1.251136e-2
GO:0006787 porphyrin-containing compound catabolic process 1.251136e-2
GO:0006690 icosanoid metabolic process 1.276301e-2
GO:0032108 negative regulation of response to nutrient levels 1.284225e-2
GO:0046823 negative regulation of nucleocytoplasmic transport 1.286406e-2
GO:0032856 activation of Ras GTPase activity 1.289138e-2
GO:0030728 ovulation 1.318511e-2
GO:0022009 central nervous system vasculogenesis 1.324348e-2
GO:0032488 Cdc42 protein signal transduction 1.349668e-2
GO:0003347 epicardial cell to mesenchymal cell transition 1.351717e-2
GO:0045765 regulation of angiogenesis 1.357652e-2
GO:0045995 regulation of embryonic development 1.389523e-2
GO:0051089 constitutive protein ectodomain proteolysis 1.395842e-2
GO:0070836 caveola assembly 1.395842e-2
GO:0035583 negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta 1.395842e-2
GO:0019240 citrulline biosynthetic process 1.395842e-2
GO:0048583 regulation of response to stimulus 1.399750e-2
GO:0050907 detection of chemical stimulus involved in sensory perception 1.429607e-2
GO:0051705 behavioral interaction between organisms 1.442662e-2
GO:0072513 positive regulation of secondary heart field cardioblast proliferation 1.443401e-2
GO:0003272 endocardial cushion formation 1.452069e-2
GO:0043501 skeletal muscle adaptation 1.453701e-2