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Novel motif:8

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name:motif8_CCATGN

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0031960 response to corticosteroid stimulus 2.006896e-22
GO:0051384 response to glucocorticoid stimulus 5.518635e-19
GO:0003008 system process 3.275161e-14
GO:0065008 regulation of biological quality 6.539789e-14
GO:0014050 negative regulation of glutamate secretion 7.197006e-14
GO:0000302 response to reactive oxygen species 1.229971e-13
GO:0009612 response to mechanical stimulus 4.551314e-13
GO:0016064 immunoglobulin mediated immune response 4.761941e-13
GO:2000660 negative regulation of interleukin-1-mediated signaling pathway 5.994668e-13
GO:0006956 complement activation 6.702598e-13
GO:0002455 humoral immune response mediated by circulating immunoglobulin 1.522366e-12
GO:0006629 lipid metabolic process 1.881331e-12
GO:0072376 protein activation cascade 2.031312e-12
GO:0019724 B cell mediated immunity 2.671003e-12
GO:0008203 cholesterol metabolic process 3.295822e-12
GO:0006955 immune response 3.533453e-12
GO:0051346 negative regulation of hydrolase activity 2.930543e-11
GO:0002439 chronic inflammatory response to antigenic stimulus 3.004160e-11
GO:0009628 response to abiotic stimulus 3.319353e-11
GO:0007586 digestion 3.606403e-11
GO:0050877 neurological system process 4.415767e-11
GO:0002544 chronic inflammatory response 5.448263e-11
GO:0034369 plasma lipoprotein particle remodeling 6.494248e-11
GO:0002449 lymphocyte mediated immunity 6.522467e-11
GO:0007601 visual perception 8.688325e-11
GO:0016125 sterol metabolic process 9.580293e-11
GO:0050953 sensory perception of light stimulus 1.266488e-10
GO:0006958 complement activation, classical pathway 1.415565e-10
GO:0030198 extracellular matrix organization 1.697890e-10
GO:0007506 gonadal mesoderm development 1.895377e-10
GO:0007600 sensory perception 2.005270e-10
GO:0032501 multicellular organismal process 2.386611e-10
GO:0010466 negative regulation of peptidase activity 2.499818e-10
GO:0044281 small molecule metabolic process 6.922951e-10
GO:0006707 cholesterol catabolic process 1.063924e-9
GO:0032101 regulation of response to external stimulus 1.385138e-9
GO:0002526 acute inflammatory response 1.423852e-9
GO:0042060 wound healing 1.430482e-9
GO:0051293 establishment of spindle localization 1.441653e-9
GO:0009408 response to heat 1.534943e-9
GO:0032368 regulation of lipid transport 1.605871e-9
GO:0071827 plasma lipoprotein particle organization 1.714201e-9
GO:0051234 establishment of localization 2.085862e-9
GO:0051704 multi-organism process 2.763430e-9
GO:0006953 acute-phase response 2.789514e-9
GO:0010035 response to inorganic substance 3.071195e-9
GO:0006979 response to oxidative stress 3.448321e-9
GO:0006810 transport 3.611923e-9
GO:0071732 cellular response to nitric oxide 4.252086e-9
GO:0008202 steroid metabolic process 4.304220e-9
GO:0002443 leukocyte mediated immunity 4.715288e-9
GO:0006950 response to stress 4.765181e-9
GO:0002250 adaptive immune response 4.884078e-9
GO:0042157 lipoprotein metabolic process 5.574171e-9
GO:0034374 low-density lipoprotein particle remodeling 5.623945e-9
GO:0050776 regulation of immune response 7.447676e-9
GO:0009611 response to wounding 8.408656e-9
GO:0050878 regulation of body fluid levels 9.216039e-9
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.101223e-8
GO:0052547 regulation of peptidase activity 1.128304e-8
GO:0010872 regulation of cholesterol esterification 1.270925e-8
GO:0014048 regulation of glutamate secretion 1.437936e-8
GO:0051179 localization 1.487196e-8
GO:0051271 negative regulation of cellular component movement 1.521322e-8
GO:0050994 regulation of lipid catabolic process 1.544418e-8
GO:0071702 organic substance transport 1.795711e-8
GO:0032964 collagen biosynthetic process 1.899178e-8
GO:0006959 humoral immune response 1.932149e-8
GO:0015914 phospholipid transport 2.710804e-8
GO:0002253 activation of immune response 3.286221e-8
GO:0002252 immune effector process 3.303092e-8
GO:0044236 multicellular organismal metabolic process 3.484010e-8
GO:0006952 defense response 4.002528e-8
GO:0051049 regulation of transport 4.350967e-8
GO:0017144 drug metabolic process 4.427558e-8
GO:0002432 granuloma formation 4.648397e-8
GO:0050896 response to stimulus 4.688043e-8
GO:0006982 response to lipid hydroperoxide 5.090385e-8
GO:0008078 mesodermal cell migration 5.830889e-8
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 6.074433e-8
GO:0034114 regulation of heterotypic cell-cell adhesion 6.074433e-8
GO:0031581 hemidesmosome assembly 6.090388e-8
GO:0050778 positive regulation of immune response 6.104313e-8
GO:0000132 establishment of mitotic spindle orientation 6.194340e-8
GO:0050996 positive regulation of lipid catabolic process 8.220674e-8
GO:0042592 homeostatic process 9.254471e-8
GO:0009582 detection of abiotic stimulus 9.419038e-8
GO:0009620 response to fungus 9.948149e-8
GO:0040001 establishment of mitotic spindle localization 1.022625e-7
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 1.060326e-7
GO:0044089 positive regulation of cellular component biogenesis 1.064416e-7
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 1.077650e-7
GO:0007568 aging 1.081711e-7
GO:0006766 vitamin metabolic process 1.086046e-7
GO:0015918 sterol transport 1.168917e-7
GO:0045590 negative regulation of regulatory T cell differentiation 1.186367e-7
GO:0030301 cholesterol transport 1.511494e-7
GO:0009607 response to biotic stimulus 1.533978e-7
GO:0007602 phototransduction 1.547913e-7
GO:0030168 platelet activation 1.627913e-7
GO:0006811 ion transport 1.651319e-7
GO:0030157 pancreatic juice secretion 1.698333e-7
GO:0051048 negative regulation of secretion 1.731903e-7
GO:0006702 androgen biosynthetic process 1.820852e-7
GO:0006869 lipid transport 1.846033e-7
GO:0060047 heart contraction 2.033310e-7
GO:0044057 regulation of system process 2.110622e-7
GO:0002682 regulation of immune system process 2.184886e-7
GO:0010876 lipid localization 2.205441e-7
GO:0051336 regulation of hydrolase activity 2.339986e-7
GO:0030336 negative regulation of cell migration 2.545785e-7
GO:0097006 regulation of plasma lipoprotein particle levels 2.598107e-7
GO:0006200 ATP catabolic process 2.748165e-7
GO:0022414 reproductive process 2.763643e-7
GO:0034115 negative regulation of heterotypic cell-cell adhesion 2.778917e-7
GO:0022038 corpus callosum development 2.876904e-7
GO:2000146 negative regulation of cell motility 2.999169e-7
GO:0050727 regulation of inflammatory response 3.213275e-7
GO:0000003 reproduction 3.240747e-7
GO:0051707 response to other organism 3.396511e-7
GO:0033273 response to vitamin 3.427850e-7
GO:0032374 regulation of cholesterol transport 3.514907e-7
GO:0045112 integrin biosynthetic process 3.788898e-7
GO:0042744 hydrogen peroxide catabolic process 3.814741e-7
GO:0007522 visceral muscle development 4.007766e-7
GO:0032879 regulation of localization 4.015227e-7
GO:0043086 negative regulation of catalytic activity 4.085303e-7
GO:0042730 fibrinolysis 4.444696e-7
GO:0046034 ATP metabolic process 4.555670e-7
GO:0002478 antigen processing and presentation of exogenous peptide antigen 4.996323e-7
GO:0006706 steroid catabolic process 5.322887e-7
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 5.396088e-7
GO:0006565 L-serine catabolic process 5.690428e-7
GO:0003012 muscle system process 6.358450e-7
GO:0071482 cellular response to light stimulus 6.865175e-7
GO:0032370 positive regulation of lipid transport 7.108110e-7
GO:2000659 regulation of interleukin-1-mediated signaling pathway 7.500348e-7
GO:0019884 antigen processing and presentation of exogenous antigen 7.822045e-7
GO:0051128 regulation of cellular component organization 8.367337e-7
GO:0060048 cardiac muscle contraction 8.893343e-7
GO:0007599 hemostasis 9.141398e-7
GO:0031667 response to nutrient levels 9.263044e-7
GO:0070098 chemokine-mediated signaling pathway 9.932689e-7
GO:0008544 epidermis development 9.954938e-7
GO:0043691 reverse cholesterol transport 1.057654e-6
GO:0042866 pyruvate biosynthetic process 1.072775e-6
GO:0032094 response to food 1.076920e-6
GO:0016043 cellular component organization 1.193290e-6
GO:0033344 cholesterol efflux 1.220242e-6
GO:0007596 blood coagulation 1.248251e-6
GO:0016042 lipid catabolic process 1.250698e-6
GO:0071840 cellular component organization or biogenesis 1.253686e-6
GO:0010470 regulation of gastrulation 1.308005e-6
GO:0002237 response to molecule of bacterial origin 1.309931e-6
GO:0033189 response to vitamin A 1.331822e-6
GO:0002376 immune system process 1.394518e-6
GO:0001659 temperature homeostasis 1.430081e-6
GO:0009583 detection of light stimulus 1.450195e-6
GO:0009069 serine family amino acid metabolic process 1.459057e-6
GO:0007154 cell communication 1.471620e-6
GO:0007584 response to nutrient 1.531563e-6
GO:0040013 negative regulation of locomotion 1.657173e-6
GO:0048878 chemical homeostasis 1.712714e-6
GO:0001936 regulation of endothelial cell proliferation 1.758446e-6
GO:0032526 response to retinoic acid 1.798743e-6
GO:0015874 norepinephrine transport 1.914387e-6
GO:0034104 negative regulation of tissue remodeling 1.976651e-6
GO:0007320 insemination 1.997361e-6
GO:0080134 regulation of response to stress 2.155552e-6
GO:0033198 response to ATP 2.197311e-6
GO:0060252 positive regulation of glial cell proliferation 2.229939e-6
GO:0009991 response to extracellular stimulus 2.269081e-6
GO:0052697 xenobiotic glucuronidation 2.345216e-6
GO:0070980 biphenyl catabolic process 2.345216e-6
GO:0051552 flavone metabolic process 2.345216e-6
GO:0006789 bilirubin conjugation 2.345216e-6
GO:0052696 flavonoid glucuronidation 2.345216e-6
GO:0051965 positive regulation of synapse assembly 2.374833e-6
GO:0009259 ribonucleotide metabolic process 2.380988e-6
GO:0042542 response to hydrogen peroxide 2.420507e-6
GO:0019538 protein metabolic process 2.437169e-6
GO:0006457 protein folding 2.488891e-6
GO:0018350 protein esterification 2.767789e-6
GO:0044258 intestinal lipid catabolic process 2.767789e-6
GO:0052548 regulation of endopeptidase activity 2.865925e-6
GO:0033700 phospholipid efflux 2.944140e-6
GO:0018298 protein-chromophore linkage 2.953227e-6
GO:0002684 positive regulation of immune system process 2.991993e-6
GO:0043069 negative regulation of programmed cell death 3.017546e-6
GO:0045414 regulation of interleukin-8 biosynthetic process 3.087641e-6
GO:0006954 inflammatory response 3.103651e-6
GO:0043066 negative regulation of apoptosis 3.287870e-6
GO:0007186 G-protein coupled receptor protein signaling pathway 3.367835e-6
GO:0010873 positive regulation of cholesterol esterification 4.985529e-6
GO:0010625 positive regulation of Schwann cell proliferation 5.059838e-6
GO:0016056 rhodopsin mediated signaling pathway 5.132821e-6
GO:0001938 positive regulation of endothelial cell proliferation 5.473931e-6
GO:0090140 regulation of mitochondrial fission 5.748253e-6
GO:0070482 response to oxygen levels 5.834971e-6
GO:0009617 response to bacterium 6.004242e-6
GO:0090026 positive regulation of monocyte chemotaxis 6.005962e-6
GO:0009113 purine base biosynthetic process 6.005962e-6
GO:0050881 musculoskeletal movement 6.147682e-6
GO:0045471 response to ethanol 6.164731e-6
GO:0090181 regulation of cholesterol metabolic process 6.843653e-6
GO:0009314 response to radiation 6.860173e-6
GO:0032496 response to lipopolysaccharide 6.887549e-6
GO:0023052 signaling 7.058085e-6
GO:0050679 positive regulation of epithelial cell proliferation 7.063542e-6
GO:0032463 negative regulation of protein homooligomerization 7.151630e-6
GO:0018879 biphenyl metabolic process 7.228638e-6
GO:0009266 response to temperature stimulus 7.306843e-6
GO:0032689 negative regulation of interferon-gamma production 7.602801e-6
GO:0042256 mature ribosome assembly 7.821640e-6
GO:0014805 smooth muscle adaptation 7.975446e-6
GO:0070232 regulation of T cell apoptosis 8.046469e-6
GO:0071300 cellular response to retinoic acid 8.353461e-6
GO:0060548 negative regulation of cell death 8.788644e-6
GO:0002685 regulation of leukocyte migration 8.905372e-6
GO:0050433 regulation of catecholamine secretion 8.974628e-6
GO:0090130 tissue migration 9.370631e-6
GO:0044092 negative regulation of molecular function 9.500635e-6
GO:0002437 inflammatory response to antigenic stimulus 9.546277e-6
GO:0007162 negative regulation of cell adhesion 9.687593e-6
GO:0009150 purine ribonucleotide metabolic process 9.791899e-6
GO:0042632 cholesterol homeostasis 1.029384e-5
GO:0007509 mesoderm migration involved in gastrulation 1.064799e-5
GO:0010817 regulation of hormone levels 1.066897e-5
GO:0044259 multicellular organismal macromolecule metabolic process 1.075528e-5
GO:0032411 positive regulation of transporter activity 1.076759e-5
GO:0007267 cell-cell signaling 1.082989e-5
GO:0051716 cellular response to stimulus 1.084715e-5
GO:0009071 serine family amino acid catabolic process 1.084748e-5
GO:0009144 purine nucleoside triphosphate metabolic process 1.127077e-5
GO:0050995 negative regulation of lipid catabolic process 1.137476e-5
GO:0048583 regulation of response to stimulus 1.154401e-5
GO:0030300 regulation of intestinal cholesterol absorption 1.183911e-5
GO:0002679 respiratory burst involved in defense response 1.384061e-5
GO:0042221 response to chemical stimulus 1.404550e-5
GO:0048545 response to steroid hormone stimulus 1.414958e-5
GO:0001666 response to hypoxia 1.422914e-5
GO:0034614 cellular response to reactive oxygen species 1.518561e-5
GO:0048844 artery morphogenesis 1.550668e-5
GO:0044240 multicellular organismal lipid catabolic process 1.563177e-5
GO:0043542 endothelial cell migration 1.643215e-5
GO:0002019 regulation of renal output by angiotensin 1.651739e-5
GO:0007166 cell surface receptor linked signaling pathway 1.655951e-5
GO:0051014 actin filament severing 1.657805e-5
GO:0006916 anti-apoptosis 1.712307e-5
GO:0014070 response to organic cyclic compound 1.748811e-5
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 1.752931e-5
GO:0070228 regulation of lymphocyte apoptosis 1.822787e-5
GO:0050807 regulation of synapse organization 1.875168e-5
GO:0006897 endocytosis 1.905786e-5
GO:0043534 blood vessel endothelial cell migration 1.917866e-5
GO:2000107 negative regulation of leukocyte apoptosis 1.945415e-5
GO:0009416 response to light stimulus 1.967858e-5
GO:0050906 detection of stimulus involved in sensory perception 1.991920e-5
GO:0000088 mitotic prophase 2.020402e-5
GO:0044241 lipid digestion 2.040364e-5
GO:0045765 regulation of angiogenesis 2.077999e-5
GO:0010951 negative regulation of endopeptidase activity 2.122526e-5
GO:0034762 regulation of transmembrane transport 2.175772e-5
GO:0033129 positive regulation of histone phosphorylation 2.185722e-5
GO:0043113 receptor clustering 2.190742e-5
GO:0003084 positive regulation of systemic arterial blood pressure 2.216386e-5
GO:0002697 regulation of immune effector process 2.230592e-5
GO:0003009 skeletal muscle contraction 2.237056e-5
GO:0072522 purine-containing compound biosynthetic process 2.250440e-5
GO:0070243 regulation of thymocyte apoptosis 2.288890e-5
GO:0051051 negative regulation of transport 2.297089e-5
GO:0050848 regulation of calcium-mediated signaling 2.379643e-5
GO:0048243 norepinephrine secretion 2.396573e-5
GO:0006163 purine nucleotide metabolic process 2.469945e-5
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process 2.488789e-5
GO:0019226 transmission of nerve impulse 2.518272e-5
GO:0043269 regulation of ion transport 2.565612e-5
GO:0009605 response to external stimulus 2.616350e-5
GO:0032103 positive regulation of response to external stimulus 2.836102e-5
GO:0043243 positive regulation of protein complex disassembly 2.844315e-5
GO:0010243 response to organic nitrogen 2.873695e-5
GO:0006164 purine nucleotide biosynthetic process 2.888423e-5
GO:0006066 alcohol metabolic process 2.909606e-5
GO:0051606 detection of stimulus 3.007709e-5
GO:2000649 regulation of sodium ion transmembrane transporter activity 3.055218e-5
GO:0032963 collagen metabolic process 3.064420e-5
GO:0009141 nucleoside triphosphate metabolic process 3.081318e-5
GO:0070229 negative regulation of lymphocyte apoptosis 3.101642e-5
GO:0001508 regulation of action potential 3.203474e-5
GO:0043270 positive regulation of ion transport 3.278774e-5
GO:0006775 fat-soluble vitamin metabolic process 3.294406e-5
GO:0060014 granulosa cell differentiation 3.316453e-5
GO:0010812 negative regulation of cell-substrate adhesion 3.358578e-5
GO:0045540 regulation of cholesterol biosynthetic process 3.364986e-5
GO:0010193 response to ozone 3.814402e-5
GO:0002238 response to molecule of fungal origin 3.856002e-5
GO:0071299 cellular response to vitamin A 3.869455e-5
GO:0046390 ribose phosphate biosynthetic process 3.894826e-5
GO:0009260 ribonucleotide biosynthetic process 3.920229e-5
GO:0018904 organic ether metabolic process 3.957011e-5
GO:0070301 cellular response to hydrogen peroxide 4.129291e-5
GO:0019221 cytokine-mediated signaling pathway 4.175253e-5
GO:0000413 protein peptidyl-prolyl isomerization 4.225821e-5
GO:0051580 regulation of neurotransmitter uptake 4.283026e-5
GO:0071496 cellular response to external stimulus 4.352454e-5
GO:0001775 cell activation 4.469798e-5
GO:0032972 regulation of muscle filament sliding speed 4.543069e-5
GO:0002149 hypochlorous acid biosynthetic process 4.562813e-5
GO:0009205 purine ribonucleoside triphosphate metabolic process 4.723552e-5
GO:0032959 inositol trisphosphate biosynthetic process 4.734316e-5
GO:0060167 regulation of adenosine receptor signaling pathway 4.795853e-5
GO:0002315 marginal zone B cell differentiation 4.795853e-5
GO:0045064 T-helper 2 cell differentiation 4.795853e-5
GO:0090205 positive regulation of cholesterol metabolic process 4.866236e-5
GO:0051963 regulation of synapse assembly 4.920465e-5
GO:0072593 reactive oxygen species metabolic process 4.987991e-5
GO:0009146 purine nucleoside triphosphate catabolic process 4.990340e-5
GO:0071385 cellular response to glucocorticoid stimulus 5.011853e-5
GO:0007398 ectoderm development 5.070136e-5
GO:0043983 histone H4-K12 acetylation 5.264035e-5
GO:0002673 regulation of acute inflammatory response 5.326079e-5
GO:0045589 regulation of regulatory T cell differentiation 5.347823e-5
GO:0002028 regulation of sodium ion transport 5.350056e-5
GO:0010874 regulation of cholesterol efflux 5.353400e-5
GO:0016192 vesicle-mediated transport 5.390214e-5
GO:0009165 nucleotide biosynthetic process 5.482144e-5
GO:0071260 cellular response to mechanical stimulus 5.544182e-5
GO:0032456 endocytic recycling 5.632801e-5
GO:2000106 regulation of leukocyte apoptosis 5.696160e-5
GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway 5.894493e-5
GO:0009199 ribonucleoside triphosphate metabolic process 5.903797e-5
GO:0009895 negative regulation of catabolic process 5.910675e-5
GO:0010933 positive regulation of macrophage tolerance induction 6.037863e-5
GO:0009143 nucleoside triphosphate catabolic process 6.237799e-5
GO:0046070 dGTP metabolic process 6.264109e-5
GO:0031444 slow-twitch skeletal muscle fiber contraction 6.264109e-5
GO:0055086 nucleobase-containing small molecule metabolic process 6.284177e-5
GO:0022617 extracellular matrix disassembly 6.322710e-5
GO:0060840 artery development 6.378807e-5
GO:0002906 negative regulation of mature B cell apoptosis 6.491762e-5
GO:0051967 negative regulation of synaptic transmission, glutamatergic 6.511815e-5
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.700364e-5
GO:0046122 purine deoxyribonucleoside metabolic process 7.122746e-5
GO:0009207 purine ribonucleoside triphosphate catabolic process 7.134417e-5
GO:0002891 positive regulation of immunoglobulin mediated immune response 7.212561e-5
GO:0032649 regulation of interferon-gamma production 7.268894e-5
GO:0006703 estrogen biosynthetic process 7.296779e-5
GO:0010896 regulation of triglyceride catabolic process 7.394966e-5
GO:0043206 fibril organization 7.439438e-5
GO:0001867 complement activation, lectin pathway 7.752069e-5
GO:2000651 positive regulation of sodium ion transmembrane transporter activity 8.381735e-5
GO:0006812 cation transport 8.747433e-5
GO:0046903 secretion 8.904414e-5
GO:0055114 oxidation-reduction process 9.097590e-5
GO:0009261 ribonucleotide catabolic process 9.136274e-5
GO:0061024 membrane organization 9.372393e-5
GO:0008015 blood circulation 9.766795e-5
GO:0009154 purine ribonucleotide catabolic process 9.781174e-5
GO:0051241 negative regulation of multicellular organismal process 9.915062e-5
GO:0031347 regulation of defense response 9.951505e-5
GO:0060333 interferon-gamma-mediated signaling pathway 1.000975e-4
GO:2000193 positive regulation of fatty acid transport 1.013169e-4
GO:0051092 positive regulation of NF-kappaB transcription factor activity 1.023933e-4
GO:0001101 response to acid 1.024372e-4
GO:0006544 glycine metabolic process 1.046362e-4
GO:0032414 positive regulation of ion transmembrane transporter activity 1.062571e-4
GO:0070884 regulation of calcineurin-NFAT signaling pathway 1.081724e-4
GO:0046100 hypoxanthine metabolic process 1.081724e-4
GO:0009117 nucleotide metabolic process 1.109766e-4
GO:0002712 regulation of B cell mediated immunity 1.128702e-4
GO:0060319 primitive erythrocyte differentiation 1.159494e-4
GO:0002575 basophil chemotaxis 1.159494e-4
GO:0034378 chylomicron assembly 1.208481e-4
GO:0061049 cell growth involved in cardiac muscle cell development 1.208481e-4
GO:0046491 L-methylmalonyl-CoA metabolic process 1.208481e-4
GO:0014873 response to muscle activity involved in regulation of muscle adaptation 1.208481e-4
GO:0003331 positive regulation of extracellular matrix constituent secretion 1.208481e-4
GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure 1.208481e-4
GO:0032308 positive regulation of prostaglandin secretion 1.220276e-4
GO:0010885 regulation of cholesterol storage 1.224993e-4
GO:0006936 muscle contraction 1.226771e-4
GO:0010038 response to metal ion 1.262185e-4
GO:0048167 regulation of synaptic plasticity 1.292940e-4
GO:0071206 establishment of protein localization to juxtaparanode region of axon 1.315562e-4
GO:0060168 positive regulation of adenosine receptor signaling pathway 1.315562e-4
GO:0009581 detection of external stimulus 1.326584e-4
GO:0001660 fever generation 1.330750e-4
GO:0032958 inositol phosphate biosynthetic process 1.360014e-4
GO:0040012 regulation of locomotion 1.370684e-4
GO:0035176 social behavior 1.380200e-4
GO:0006348 chromatin silencing at telomere 1.382637e-4
GO:0000917 barrier septum formation 1.382637e-4
GO:0045087 innate immune response 1.385683e-4
GO:0072521 purine-containing compound metabolic process 1.433251e-4
GO:0060346 bone trabecula formation 1.453327e-4
GO:0002686 negative regulation of leukocyte migration 1.466159e-4
GO:0003051 angiotensin-mediated drinking behavior 1.467200e-4
GO:0003015 heart process 1.492441e-4
GO:2000191 regulation of fatty acid transport 1.494391e-4
GO:0034654 nucleobase-containing compound biosynthetic process 1.521920e-4
GO:0010959 regulation of metal ion transport 1.562550e-4
GO:0060992 response to fungicide 1.569889e-4
GO:0006638 neutral lipid metabolic process 1.586552e-4
GO:0043933 macromolecular complex subunit organization 1.626634e-4
GO:0007165 signal transduction 1.631662e-4
GO:0018026 peptidyl-lysine monomethylation 1.639184e-4
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion 1.642038e-4
GO:0055009 atrial cardiac muscle tissue morphogenesis 1.645768e-4
GO:0016044 cellular membrane organization 1.661127e-4
GO:0046851 negative regulation of bone remodeling 1.666146e-4
GO:0046165 alcohol biosynthetic process 1.701772e-4
GO:0009151 purine deoxyribonucleotide metabolic process 1.725646e-4
GO:0007618 mating 1.731162e-4
GO:0051928 positive regulation of calcium ion transport 1.731650e-4
GO:0060744 mammary gland branching involved in thelarche 1.768867e-4
GO:0008210 estrogen metabolic process 1.783015e-4
GO:0051270 regulation of cellular component movement 1.783062e-4
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 1.805859e-4
GO:0046101 hypoxanthine biosynthetic process 1.805996e-4
GO:0050832 defense response to fungus 1.835775e-4
GO:0009264 deoxyribonucleotide catabolic process 1.854617e-4
GO:0045542 positive regulation of cholesterol biosynthetic process 1.859326e-4
GO:0035814 negative regulation of renal sodium excretion 1.859326e-4
GO:0014059 regulation of dopamine secretion 1.890235e-4
GO:0051952 regulation of amine transport 1.894766e-4
GO:0006898 receptor-mediated endocytosis 1.902631e-4
GO:0006941 striated muscle contraction 1.905014e-4
GO:0007268 synaptic transmission 1.927967e-4
GO:0045779 negative regulation of bone resorption 1.950787e-4
GO:0019725 cellular homeostasis 1.955220e-4
GO:0033194 response to hydroperoxide 1.967355e-4
GO:0002889 regulation of immunoglobulin mediated immune response 2.015990e-4
GO:0001568 blood vessel development 2.022205e-4
GO:0019233 sensory perception of pain 2.030614e-4
GO:0009394 2'-deoxyribonucleotide metabolic process 2.055725e-4
GO:0048609 multicellular organismal reproductive process 2.066230e-4
GO:0032729 positive regulation of interferon-gamma production 2.078942e-4
GO:0046483 heterocycle metabolic process 2.100183e-4
GO:0015992 proton transport 2.101177e-4
GO:0070327 thyroid hormone transport 2.118545e-4
GO:0002675 positive regulation of acute inflammatory response 2.131451e-4
GO:0006879 cellular iron ion homeostasis 2.235272e-4
GO:0001922 B-1 B cell homeostasis 2.263099e-4
GO:0006725 cellular aromatic compound metabolic process 2.268774e-4
GO:0044243 multicellular organismal catabolic process 2.322028e-4
GO:0018022 peptidyl-lysine methylation 2.345617e-4
GO:0071214 cellular response to abiotic stimulus 2.367630e-4
GO:0006749 glutathione metabolic process 2.448864e-4
GO:0090141 positive regulation of mitochondrial fission 2.482835e-4
GO:0042756 drinking behavior 2.508613e-4
GO:0051259 protein oligomerization 2.513747e-4
GO:0035313 wound healing, spreading of epidermal cells 2.519616e-4
GO:0050851 antigen receptor-mediated signaling pathway 2.524998e-4
GO:0003013 circulatory system process 2.529401e-4
GO:0007155 cell adhesion 2.533255e-4
GO:0006641 triglyceride metabolic process 2.543569e-4
GO:0070244 negative regulation of thymocyte apoptosis 2.544757e-4
GO:0019228 regulation of action potential in neuron 2.572368e-4
GO:0007492 endoderm development 2.584339e-4
GO:0051323 metaphase 2.594586e-4
GO:0009215 purine deoxyribonucleoside triphosphate metabolic process 2.602412e-4
GO:0002768 immune response-regulating cell surface receptor signaling pathway 2.685851e-4
GO:2000145 regulation of cell motility 2.761273e-4
GO:0002429 immune response-activating cell surface receptor signaling pathway 2.787818e-4
GO:0009262 deoxyribonucleotide metabolic process 2.796576e-4
GO:0009152 purine ribonucleotide biosynthetic process 2.811147e-4
GO:0042445 hormone metabolic process 2.886191e-4
GO:0072334 UDP-galactose transmembrane transport 2.888654e-4
GO:0034599 cellular response to oxidative stress 2.918802e-4
GO:0048584 positive regulation of response to stimulus 2.941605e-4
GO:0015670 carbon dioxide transport 2.949050e-4
GO:0070508 cholesterol import 2.978172e-4
GO:0070164 negative regulation of adiponectin secretion 3.003538e-4
GO:0035505 positive regulation of myosin light chain kinase activity 3.003538e-4
GO:0060355 positive regulation of cell adhesion molecule production 3.003538e-4
GO:0002268 follicular dendritic cell differentiation 3.021938e-4
GO:0042116 macrophage activation 3.074611e-4
GO:0033504 floor plate development 3.079403e-4
GO:0051656 establishment of organelle localization 3.108160e-4
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 3.169066e-4
GO:0060020 Bergmann glial cell differentiation 3.182214e-4
GO:0007589 body fluid secretion 3.187952e-4
GO:0048514 blood vessel morphogenesis 3.219535e-4
GO:0006821 chloride transport 3.265944e-4
GO:0006639 acylglycerol metabolic process 3.319566e-4
GO:0007566 embryo implantation 3.357020e-4
GO:0032892 positive regulation of organic acid transport 3.412210e-4
GO:0033127 regulation of histone phosphorylation 3.416627e-4
GO:0072205 metanephric collecting duct development 3.430646e-4
GO:0085018 maintenance of symbiont-containing vacuole via substance secreted by host 3.471004e-4
GO:0035378 carbon dioxide transmembrane transport 3.471004e-4
GO:0030950 establishment or maintenance of actin cytoskeleton polarity 3.471004e-4
GO:0035377 transepithelial water transport 3.471004e-4
GO:0070234 positive regulation of T cell apoptosis 3.495517e-4
GO:0031133 regulation of axon diameter 3.536573e-4
GO:0071472 cellular response to salt stress 3.546328e-4
GO:0072488 ammonium transmembrane transport 3.546328e-4
GO:0034097 response to cytokine stimulus 3.569554e-4
GO:0018027 peptidyl-lysine dimethylation 3.587989e-4
GO:0048610 cellular process involved in reproduction 3.606112e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0008202 steroid metabolic process 1.294353e-21
GO:0055114 oxidation-reduction process 4.105637e-16
GO:0006629 lipid metabolic process 1.139984e-15
GO:0033344 cholesterol efflux 4.252235e-15
GO:0008203 cholesterol metabolic process 4.324978e-15
GO:0034369 plasma lipoprotein particle remodeling 7.843236e-15
GO:0071827 plasma lipoprotein particle organization 1.337642e-14
GO:0016125 sterol metabolic process 1.662210e-14
GO:0044281 small molecule metabolic process 3.095416e-14
GO:0097006 regulation of plasma lipoprotein particle levels 4.203478e-12
GO:0030301 cholesterol transport 4.450404e-12
GO:0008610 lipid biosynthetic process 1.235996e-11
GO:0044255 cellular lipid metabolic process 1.254223e-11
GO:0006082 organic acid metabolic process 1.588314e-11
GO:0019752 carboxylic acid metabolic process 1.987761e-11
GO:0042632 cholesterol homeostasis 2.662451e-11
GO:0042180 cellular ketone metabolic process 3.373265e-11
GO:0032374 regulation of cholesterol transport 1.416482e-10
GO:0044242 cellular lipid catabolic process 2.499421e-10
GO:0015914 phospholipid transport 7.306334e-10
GO:0042446 hormone biosynthetic process 7.837817e-10
GO:0043691 reverse cholesterol transport 7.959664e-10
GO:0006066 alcohol metabolic process 1.761658e-9
GO:0018904 organic ether metabolic process 3.002830e-9
GO:0030300 regulation of intestinal cholesterol absorption 4.080547e-9
GO:0006869 lipid transport 5.028507e-9
GO:0009308 amine metabolic process 5.749884e-9
GO:0006639 acylglycerol metabolic process 6.932190e-9
GO:0033700 phospholipid efflux 9.099804e-9
GO:0070328 triglyceride homeostasis 1.198577e-8
GO:0006694 steroid biosynthetic process 1.423470e-8
GO:0046464 acylglycerol catabolic process 1.760722e-8
GO:0032368 regulation of lipid transport 1.837469e-8
GO:0042157 lipoprotein metabolic process 2.086063e-8
GO:0000305 response to oxygen radical 2.360465e-8
GO:0055088 lipid homeostasis 3.231675e-8
GO:0006641 triglyceride metabolic process 3.354205e-8
GO:0046474 glycerophospholipid biosynthetic process 3.375261e-8
GO:0006662 glycerol ether metabolic process 4.674081e-8
GO:0006638 neutral lipid metabolic process 4.959808e-8
GO:0006952 defense response 5.079276e-8
GO:0006642 triglyceride mobilization 5.095177e-8
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 6.721052e-8
GO:0022410 circadian sleep/wake cycle process 7.741872e-8
GO:0046503 glycerolipid catabolic process 8.525548e-8
GO:0019433 triglyceride catabolic process 9.291667e-8
GO:0008207 C21-steroid hormone metabolic process 9.807232e-8
GO:0010876 lipid localization 1.000714e-7
GO:0042745 circadian sleep/wake cycle 1.136500e-7
GO:0042744 hydrogen peroxide catabolic process 1.278439e-7
GO:0031424 keratinization 1.389726e-7
GO:0051659 maintenance of mitochondrion location 1.513076e-7
GO:0045589 regulation of regulatory T cell differentiation 1.812611e-7
GO:0046486 glycerolipid metabolic process 1.895337e-7
GO:0044106 cellular amine metabolic process 1.971370e-7
GO:0045017 glycerolipid biosynthetic process 2.445592e-7
GO:0010038 response to metal ion 2.540358e-7
GO:0042304 regulation of fatty acid biosynthetic process 2.548008e-7
GO:0010872 regulation of cholesterol esterification 2.792581e-7
GO:0044283 small molecule biosynthetic process 3.012605e-7
GO:0034375 high-density lipoprotein particle remodeling 3.572476e-7
GO:0016042 lipid catabolic process 3.655911e-7
GO:0006690 icosanoid metabolic process 3.715156e-7
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 3.775752e-7
GO:0044058 regulation of digestive system process 4.009780e-7
GO:0032375 negative regulation of cholesterol transport 5.988593e-7
GO:0009310 amine catabolic process 6.183682e-7
GO:0034381 plasma lipoprotein particle clearance 7.831652e-7
GO:0006636 unsaturated fatty acid biosynthetic process 8.773225e-7
GO:0006603 phosphocreatine metabolic process 8.979668e-7
GO:0034442 regulation of lipoprotein oxidation 9.458595e-7
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance 1.123711e-6
GO:0002227 innate immune response in mucosa 1.179772e-6
GO:0046394 carboxylic acid biosynthetic process 1.250921e-6
GO:0000303 response to superoxide 1.665783e-6
GO:0006954 inflammatory response 1.677857e-6
GO:0019370 leukotriene biosynthetic process 1.689904e-6
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 1.952489e-6
GO:0070508 cholesterol import 2.100792e-6
GO:0046456 icosanoid biosynthetic process 2.208021e-6
GO:0042445 hormone metabolic process 2.235043e-6
GO:0045717 negative regulation of fatty acid biosynthetic process 2.281642e-6
GO:0008654 phospholipid biosynthetic process 2.293141e-6
GO:0022900 electron transport chain 2.446661e-6
GO:0010873 positive regulation of cholesterol esterification 2.722017e-6
GO:0010984 regulation of lipoprotein particle clearance 2.828923e-6
GO:0051657 maintenance of organelle location 3.403281e-6
GO:0010982 regulation of high-density lipoprotein particle clearance 3.588723e-6
GO:0042178 xenobiotic catabolic process 3.697875e-6
GO:0032490 detection of molecule of bacterial origin 3.973519e-6
GO:0051234 establishment of localization 4.387200e-6
GO:0010035 response to inorganic substance 4.994391e-6
GO:0071870 cellular response to catecholamine stimulus 5.559875e-6
GO:0006420 arginyl-tRNA aminoacylation 5.825092e-6
GO:0009063 cellular amino acid catabolic process 6.484243e-6
GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter 7.195168e-6
GO:0006810 transport 7.210696e-6
GO:0032237 activation of store-operated calcium channel activity 7.706025e-6
GO:0010985 negative regulation of lipoprotein particle clearance 7.863684e-6
GO:0006661 phosphatidylinositol biosynthetic process 8.368478e-6
GO:0032787 monocarboxylic acid metabolic process 8.563253e-6
GO:0006700 C21-steroid hormone biosynthetic process 1.039301e-5
GO:0050704 regulation of interleukin-1 secretion 1.063541e-5
GO:0065005 protein-lipid complex assembly 1.149700e-5
GO:0045590 negative regulation of regulatory T cell differentiation 1.218857e-5
GO:0042448 progesterone metabolic process 1.267854e-5
GO:0018924 mandelate metabolic process 1.418919e-5
GO:0006691 leukotriene metabolic process 1.458996e-5
GO:0046689 response to mercury ion 1.495814e-5
GO:0044282 small molecule catabolic process 1.574343e-5
GO:0051005 negative regulation of lipoprotein lipase activity 1.711944e-5
GO:0042742 defense response to bacterium 1.755210e-5
GO:0006707 cholesterol catabolic process 1.914712e-5
GO:0045940 positive regulation of steroid metabolic process 2.017735e-5
GO:0043476 pigment accumulation 2.041256e-5
GO:0006941 striated muscle contraction 2.243869e-5
GO:0032236 positive regulation of calcium ion transport via store-operated calcium channel activity 2.403596e-5
GO:0019884 antigen processing and presentation of exogenous antigen 2.448704e-5
GO:0042747 circadian sleep/wake cycle, REM sleep 2.473245e-5
GO:0045187 regulation of circadian sleep/wake cycle, sleep 2.519386e-5
GO:0006520 cellular amino acid metabolic process 2.525748e-5
GO:0050748 negative regulation of lipoprotein metabolic process 2.693700e-5
GO:0006805 xenobiotic metabolic process 2.874285e-5
GO:0051346 negative regulation of hydrolase activity 2.994074e-5
GO:0006399 tRNA metabolic process 3.044832e-5
GO:0006957 complement activation, alternative pathway 3.131536e-5
GO:0046034 ATP metabolic process 3.398357e-5
GO:0010987 negative regulation of high-density lipoprotein particle clearance 3.452607e-5
GO:0010897 negative regulation of triglyceride catabolic process 3.452607e-5
GO:0050706 regulation of interleukin-1 beta secretion 3.636832e-5
GO:0006982 response to lipid hydroperoxide 3.874052e-5
GO:0042158 lipoprotein biosynthetic process 4.003333e-5
GO:0046395 carboxylic acid catabolic process 4.057375e-5
GO:0034382 chylomicron remnant clearance 4.062070e-5
GO:0050746 regulation of lipoprotein metabolic process 4.431031e-5
GO:0006631 fatty acid metabolic process 4.689070e-5
GO:0006725 cellular aromatic compound metabolic process 4.697673e-5
GO:0010466 negative regulation of peptidase activity 5.442430e-5
GO:0032497 detection of lipopolysaccharide 5.806833e-5
GO:0006506 GPI anchor biosynthetic process 6.151858e-5
GO:0044271 cellular nitrogen compound biosynthetic process 6.441285e-5
GO:0060620 regulation of cholesterol import 6.579608e-5
GO:0008033 tRNA processing 6.892379e-5
GO:0046755 non-lytic virus budding 6.930830e-5
GO:0042938 dipeptide transport 6.930830e-5
GO:0010269 response to selenium ion 7.258316e-5
GO:0019430 removal of superoxide radicals 7.739989e-5
GO:0055090 acylglycerol homeostasis 7.784156e-5
GO:0033198 response to ATP 7.992918e-5
GO:0010193 response to ozone 8.793224e-5
GO:0034754 cellular hormone metabolic process 1.008377e-4
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1.009221e-4
GO:0043482 cellular pigment accumulation 1.048311e-4
GO:0007159 leukocyte cell-cell adhesion 1.065051e-4
GO:0007586 digestion 1.134046e-4
GO:0051336 regulation of hydrolase activity 1.142335e-4
GO:0051707 response to other organism 1.192749e-4
GO:0060988 lipid tube assembly 1.201612e-4
GO:0009617 response to bacterium 1.221213e-4
GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.221765e-4
GO:0046130 purine ribonucleoside catabolic process 1.225618e-4
GO:0002407 dendritic cell chemotaxis 1.225618e-4
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.261809e-4
GO:0006633 fatty acid biosynthetic process 1.297523e-4
GO:0051704 multi-organism process 1.417816e-4
GO:0019836 hemolysis by symbiont of host erythrocytes 1.524101e-4
GO:0032418 lysosome localization 1.528306e-4
GO:0050873 brown fat cell differentiation 1.552755e-4
GO:0090207 regulation of triglyceride metabolic process 1.553318e-4
GO:0006547 histidine metabolic process 1.684621e-4
GO:0002253 activation of immune response 1.703883e-4
GO:0032369 negative regulation of lipid transport 1.765570e-4
GO:0010896 regulation of triglyceride catabolic process 1.779992e-4
GO:0000266 mitochondrial fission 1.781829e-4
GO:0060192 negative regulation of lipase activity 1.796836e-4
GO:0006515 misfolded or incompletely synthesized protein catabolic process 1.824455e-4
GO:0006811 ion transport 1.902607e-4
GO:0006754 ATP biosynthetic process 1.982423e-4
GO:0046470 phosphatidylcholine metabolic process 2.076800e-4
GO:0050863 regulation of T cell activation 2.154437e-4
GO:0090076 relaxation of skeletal muscle 2.158272e-4
GO:0032470 elevation of endoplasmic reticulum calcium ion concentration 2.158272e-4
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 2.175763e-4
GO:0046483 heterocycle metabolic process 2.195170e-4
GO:0015920 lipopolysaccharide transport 2.195537e-4
GO:0030889 negative regulation of B cell proliferation 2.219629e-4
GO:0070541 response to platinum ion 2.364226e-4
GO:0046314 phosphocreatine biosynthetic process 2.421007e-4
GO:0010949 negative regulation of intestinal phytosterol absorption 2.421007e-4
GO:0045796 negative regulation of intestinal cholesterol absorption 2.421007e-4
GO:0050711 negative regulation of interleukin-1 secretion 2.440670e-4
GO:0009607 response to biotic stimulus 2.502156e-4
GO:0042743 hydrogen peroxide metabolic process 2.535561e-4
GO:0046013 regulation of T cell homeostatic proliferation 2.591674e-4
GO:0002385 mucosal immune response 2.623528e-4
GO:0050872 white fat cell differentiation 2.701654e-4
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 2.726945e-4
GO:0006546 glycine catabolic process 2.754727e-4
GO:0050778 positive regulation of immune response 2.814048e-4
GO:0019637 organophosphate metabolic process 2.826109e-4
GO:0045651 positive regulation of macrophage differentiation 2.875112e-4
GO:0051875 pigment granule localization 2.877454e-4
GO:0002335 mature B cell differentiation 2.924079e-4
GO:0045922 negative regulation of fatty acid metabolic process 3.039207e-4
GO:0042439 ethanolamine-containing compound metabolic process 3.049248e-4
GO:0046466 membrane lipid catabolic process 3.146961e-4
GO:0006172 ADP biosynthetic process 3.286058e-4
GO:0033239 negative regulation of cellular amine metabolic process 3.291283e-4
GO:0051788 response to misfolded protein 3.311353e-4
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 3.336684e-4
GO:0071712 ER-associated misfolded protein catabolic process 3.348825e-4
GO:0006702 androgen biosynthetic process 3.428534e-4
GO:0002251 organ or tissue specific immune response 3.972014e-4
GO:0032853 positive regulation of Ran GTPase activity 4.109135e-4
GO:0009201 ribonucleoside triphosphate biosynthetic process 4.178835e-4
GO:0006705 mineralocorticoid biosynthetic process 4.180787e-4
GO:0010951 negative regulation of endopeptidase activity 4.181288e-4
GO:0045066 regulatory T cell differentiation 4.236020e-4
GO:0050953 sensory perception of light stimulus 4.237038e-4
GO:0009415 response to water 4.312590e-4
GO:0014819 regulation of skeletal muscle contraction 4.413797e-4
GO:0002764 immune response-regulating signaling pathway 4.431885e-4
GO:0019307 mannose biosynthetic process 4.728871e-4
GO:0032321 positive regulation of Rho GTPase activity 4.785775e-4
GO:0009260 ribonucleotide biosynthetic process 4.825521e-4
GO:0010900 negative regulation of phosphatidylcholine catabolic process 5.007891e-4
GO:0009145 purine nucleoside triphosphate biosynthetic process 5.100609e-4
GO:0010565 regulation of cellular ketone metabolic process 5.183277e-4
GO:0042752 regulation of circadian rhythm 5.195209e-4
GO:0006953 acute-phase response 5.224801e-4
GO:0031295 T cell costimulation 5.232077e-4
GO:0010817 regulation of hormone levels 5.247541e-4
GO:0007341 penetration of zona pellucida 5.250300e-4
GO:0034374 low-density lipoprotein particle remodeling 5.489512e-4
GO:0015824 proline transport 5.532391e-4
GO:0002238 response to molecule of fungal origin 5.690446e-4
GO:0006164 purine nucleotide biosynthetic process 5.775266e-4
GO:0006544 glycine metabolic process 5.780608e-4
GO:0007601 visual perception 5.791314e-4
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 5.864786e-4
GO:0035315 hair cell differentiation 5.957188e-4
GO:0034435 cholesterol esterification 6.014715e-4
GO:0010989 negative regulation of low-density lipoprotein particle clearance 6.294292e-4
GO:0009152 purine ribonucleotide biosynthetic process 6.376780e-4
GO:0016098 monoterpenoid metabolic process 6.377980e-4
GO:0006663 platelet activating factor biosynthetic process 6.377980e-4
GO:0009595 detection of biotic stimulus 6.490292e-4
GO:0043249 erythrocyte maturation 6.518391e-4
GO:0006704 glucocorticoid biosynthetic process 6.518391e-4
GO:0072362 regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter 6.773815e-4
GO:0070627 ferrous iron import 6.773815e-4
GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter 6.773815e-4
GO:0015676 vanadium ion transport 6.773815e-4
GO:0008057 eye pigment granule organization 6.773815e-4
GO:0015692 lead ion transport 6.773815e-4
GO:0035964 COPI-coated vesicle budding 6.774925e-4
GO:0006650 glycerophospholipid metabolic process 6.962168e-4
GO:0060621 negative regulation of cholesterol import 7.012920e-4
GO:0071872 cellular response to epinephrine stimulus 7.103558e-4
GO:0009235 cobalamin metabolic process 7.103558e-4
GO:0000715 nucleotide-excision repair, DNA damage recognition 7.324136e-4
GO:0071702 organic substance transport 7.328378e-4
GO:0006505 GPI anchor metabolic process 7.672258e-4
GO:0050900 leukocyte migration 7.807578e-4
GO:0002316 follicular B cell differentiation 7.841748e-4
GO:0018130 heterocycle biosynthetic process 8.013252e-4
GO:0009142 nucleoside triphosphate biosynthetic process 8.053857e-4
GO:0009117 nucleotide metabolic process 8.166182e-4
GO:0031640 killing of cells of other organism 8.230732e-4
GO:0006548 histidine catabolic process 8.261131e-4
GO:0015876 acetyl-CoA transport 8.597636e-4
GO:0051092 positive regulation of NF-kappaB transcription factor activity 8.693013e-4
GO:0046164 alcohol catabolic process 8.774792e-4
GO:0008206 bile acid metabolic process 8.788717e-4
GO:0014894 response to denervation involved in regulation of muscle adaptation 8.974297e-4
GO:0042730 fibrinolysis 9.054931e-4
GO:0002313 mature B cell differentiation involved in immune response 9.367391e-4
GO:0090026 positive regulation of monocyte chemotaxis 9.452007e-4
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 9.649977e-4
GO:0032526 response to retinoic acid 9.708248e-4
GO:0019882 antigen processing and presentation 9.724510e-4
GO:0090209 negative regulation of triglyceride metabolic process 9.735305e-4
GO:0071421 manganese ion transmembrane transport 1.013585e-3
GO:0006644 phospholipid metabolic process 1.022415e-3
GO:0045988 negative regulation of striated muscle contraction 1.038834e-3
GO:0009620 response to fungus 1.041291e-3
GO:0032652 regulation of interleukin-1 production 1.053130e-3
GO:0050713 negative regulation of interleukin-1 beta secretion 1.076129e-3
GO:0015840 urea transport 1.076129e-3
GO:0006412 translation 1.090064e-3
GO:0000038 very long-chain fatty acid metabolic process 1.125151e-3
GO:0000302 response to reactive oxygen species 1.128383e-3
GO:0019218 regulation of steroid metabolic process 1.139350e-3
GO:0006654 phosphatidic acid biosynthetic process 1.144977e-3
GO:0042404 thyroid hormone catabolic process 1.153581e-3
GO:0050729 positive regulation of inflammatory response 1.158247e-3
GO:0070059 apoptosis in response to endoplasmic reticulum stress 1.169915e-3
GO:0051883 killing of cells in other organism involved in symbiotic interaction 1.181262e-3
GO:0006497 protein lipidation 1.187346e-3
GO:0032367 intracellular cholesterol transport 1.194529e-3
GO:0030216 keratinocyte differentiation 1.203309e-3
GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1.211068e-3
GO:0046949 fatty-acyl-CoA biosynthetic process 1.211068e-3
GO:0061302 smooth muscle cell-matrix adhesion 1.211068e-3
GO:0043163 cell envelope organization 1.211068e-3
GO:0002221 pattern recognition receptor signaling pathway 1.213311e-3
GO:0002684 positive regulation of immune system process 1.215583e-3
GO:0071874 cellular response to norepinephrine stimulus 1.234022e-3
GO:0031349 positive regulation of defense response 1.242103e-3
GO:0008211 glucocorticoid metabolic process 1.244398e-3
GO:0071608 macrophage inflammatory protein-1 alpha production 1.251767e-3
GO:2000363 positive regulation of prostaglandin-E synthase activity 1.251767e-3
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 1.251767e-3
GO:0032701 negative regulation of interleukin-18 production 1.251767e-3
GO:0006965 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 1.251767e-3
GO:0032498 detection of muramyl dipeptide 1.251767e-3
GO:0052547 regulation of peptidase activity 1.252438e-3
GO:0042346 positive regulation of NF-kappaB import into nucleus 1.258187e-3
GO:0048711 positive regulation of astrocyte differentiation 1.268795e-3
GO:0051561 elevation of mitochondrial calcium ion concentration 1.279273e-3
GO:0032488 Cdc42 protein signal transduction 1.279273e-3
GO:0048535 lymph node development 1.279700e-3
GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction 1.289899e-3
GO:0046434 organophosphate catabolic process 1.307729e-3
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 1.318712e-3
GO:0032094 response to food 1.343544e-3
GO:0001845 phagolysosome assembly 1.372472e-3
GO:0042219 cellular modified amino acid catabolic process 1.380842e-3
GO:0009165 nucleotide biosynthetic process 1.382342e-3
GO:0015938 coenzyme A catabolic process 1.442142e-3
GO:0031081 nuclear pore distribution 1.442142e-3
GO:0097026 dendritic cell dendrite assembly 1.466795e-3
GO:0016559 peroxisome fission 1.466795e-3
GO:0009414 response to water deprivation 1.479651e-3
GO:0002579 positive regulation of antigen processing and presentation 1.480570e-3
GO:0002757 immune response-activating signal transduction 1.506474e-3
GO:0050869 negative regulation of B cell activation 1.511816e-3
GO:0019371 cyclooxygenase pathway 1.545980e-3
GO:0006435 threonyl-tRNA aminoacylation 1.568169e-3
GO:0035104 positive regulation of transcription via sterol regulatory element binding 1.584056e-3
GO:0060457 negative regulation of digestive system process 1.599489e-3
GO:0045415 negative regulation of interleukin-8 biosynthetic process 1.613070e-3
GO:0043550 regulation of lipid kinase activity 1.631941e-3
GO:0019369 arachidonic acid metabolic process 1.634877e-3
GO:0055085 transmembrane transport 1.640614e-3
GO:0002682 regulation of immune system process 1.650115e-3
GO:0071356 cellular response to tumor necrosis factor 1.650285e-3
GO:0015936 coenzyme A metabolic process 1.732109e-3
GO:0051222 positive regulation of protein transport 1.735138e-3
GO:0006812 cation transport 1.744550e-3
GO:0002861 regulation of inflammatory response to antigenic stimulus 1.763910e-3
GO:0048512 circadian behavior 1.790763e-3
GO:0003032 detection of oxygen 1.799852e-3
GO:0042396 phosphagen biosynthetic process 1.816026e-3
GO:0043901 negative regulation of multi-organism process 1.835169e-3
GO:0030149 sphingolipid catabolic process 1.844703e-3
GO:0042345 regulation of NF-kappaB import into nucleus 1.857002e-3
GO:0032471 reduction of endoplasmic reticulum calcium ion concentration 1.876575e-3
GO:0042537 benzene-containing compound metabolic process 1.876828e-3
GO:0034380 high-density lipoprotein particle assembly 1.918763e-3
GO:0032959 inositol trisphosphate biosynthetic process 1.948633e-3
GO:0010830 regulation of myotube differentiation 1.957239e-3
GO:0009437 carnitine metabolic process 1.964653e-3
GO:0070509 calcium ion import 1.981181e-3
GO:0016074 snoRNA metabolic process 1.981181e-3
GO:0043547 positive regulation of GTPase activity 2.018215e-3
GO:0045591 positive regulation of regulatory T cell differentiation 2.024840e-3
GO:0002376 immune system process 2.073227e-3
GO:0050870 positive regulation of T cell activation 2.092979e-3
GO:0050862 positive regulation of T cell receptor signaling pathway 2.106957e-3
GO:0006098 pentose-phosphate shunt 2.131267e-3
GO:0006720 isoprenoid metabolic process 2.142589e-3
GO:0002758 innate immune response-activating signal transduction 2.194632e-3
GO:0051249 regulation of lymphocyte activation 2.210199e-3
GO:0042993 positive regulation of transcription factor import into nucleus 2.221364e-3
GO:0097039 protein linear polyubiquitination 2.248567e-3
GO:0009913 epidermal cell differentiation 2.290348e-3
GO:0010572 positive regulation of platelet activation 2.317823e-3
GO:0019217 regulation of fatty acid metabolic process 2.328954e-3
GO:0046890 regulation of lipid biosynthetic process 2.397474e-3
GO:0006959 humoral immune response 2.402126e-3
GO:0019319 hexose biosynthetic process 2.416713e-3
GO:0010288 response to lead ion 2.460514e-3
GO:0032320 positive regulation of Ras GTPase activity 2.467080e-3
GO:0042990 regulation of transcription factor import into nucleus 2.489265e-3
GO:0002740 negative regulation of cytokine secretion involved in immune response 2.599270e-3
GO:0070574 cadmium ion transmembrane transport 2.626014e-3
GO:0034694 response to prostaglandin stimulus 2.627089e-3
GO:0001817 regulation of cytokine production 2.664887e-3
GO:0045933 positive regulation of muscle contraction 2.723436e-3
GO:0042891 antibiotic transport 2.727526e-3
GO:0051668 localization within membrane 2.746345e-3
GO:0072522 purine-containing compound biosynthetic process 2.807326e-3
GO:0060992 response to fungicide 2.844537e-3
GO:0045580 regulation of T cell differentiation 2.929930e-3
GO:0042403 thyroid hormone metabolic process 2.940048e-3
GO:0033037 polysaccharide localization 2.951813e-3
GO:0097022 lymphocyte migration into lymph node 2.969721e-3
GO:0034441 plasma lipoprotein particle oxidation 2.969721e-3
GO:0072610 interleukin-12 secretion 2.969721e-3
GO:0071218 cellular response to misfolded protein 2.970994e-3
GO:0017004 cytochrome complex assembly 2.970994e-3
GO:0071322 cellular response to carbohydrate stimulus 3.016101e-3
GO:0032319 regulation of Rho GTPase activity 3.016375e-3
GO:0006801 superoxide metabolic process 3.032622e-3
GO:0033085 negative regulation of T cell differentiation in thymus 3.093307e-3
GO:0032088 negative regulation of NF-kappaB transcription factor activity 3.118764e-3
GO:0048002 antigen processing and presentation of peptide antigen 3.142912e-3
GO:0042697 menopause 3.198316e-3
GO:0072530 purine-containing compound transmembrane transport 3.206062e-3
GO:0006818 hydrogen transport 3.262720e-3
GO:0032651 regulation of interleukin-1 beta production 3.322164e-3
GO:0023035 CD40 signaling pathway 3.425611e-3
GO:0090257 regulation of muscle system process 3.479230e-3
GO:0009583 detection of light stimulus 3.491941e-3
GO:0009593 detection of chemical stimulus 3.503087e-3
GO:2000110 negative regulation of macrophage apoptosis 3.558201e-3
GO:0050776 regulation of immune response 3.559844e-3
GO:0042984 regulation of amyloid precursor protein biosynthetic process 3.567753e-3
GO:0090218 positive regulation of lipid kinase activity 3.612709e-3
GO:0015931 nucleobase-containing compound transport 3.626300e-3
GO:0050994 regulation of lipid catabolic process 3.667577e-3
GO:0070301 cellular response to hydrogen peroxide 3.670224e-3
GO:0006955 immune response 3.717421e-3
GO:0006937 regulation of muscle contraction 3.744575e-3
GO:2000412 positive regulation of thymocyte migration 3.781484e-3
GO:0032400 melanosome localization 3.800780e-3
GO:0006599 phosphagen metabolic process 3.800780e-3
GO:0051882 mitochondrial depolarization 3.813191e-3
GO:0017126 nucleologenesis 3.813191e-3
GO:0033342 negative regulation of collagen binding 3.813191e-3
GO:0045214 sarcomere organization 3.824004e-3
GO:0046824 positive regulation of nucleocytoplasmic transport 3.824714e-3
GO:0002709 regulation of T cell mediated immunity 3.824899e-3
GO:0001935 endothelial cell proliferation 3.861995e-3
GO:0035524 proline transmembrane transport 3.900166e-3
GO:0009071 serine family amino acid catabolic process 3.907273e-3
GO:0044003 modification by symbiont of host morphology or physiology 3.934108e-3
GO:0051186 cofactor metabolic process 3.976751e-3
GO:0015842 synaptic vesicle amine transport 4.094381e-3
GO:0042761 very long-chain fatty acid biosynthetic process 4.097545e-3
GO:0003229 ventricular cardiac muscle tissue development 4.300116e-3
GO:0007602 phototransduction 4.300442e-3
GO:0003062 regulation of heart rate by chemical signal 4.322826e-3
GO:0051701 interaction with host 4.415149e-3
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling 4.433420e-3
GO:0009133 nucleoside diphosphate biosynthetic process 4.477786e-3
GO:0048247 lymphocyte chemotaxis 4.477786e-3
GO:0007584 response to nutrient 4.482534e-3
GO:0050718 positive regulation of interleukin-1 beta secretion 4.572974e-3
GO:0055010 ventricular cardiac muscle tissue morphogenesis 4.577825e-3
GO:0034614 cellular response to reactive oxygen species 4.614819e-3
GO:0010886 positive regulation of cholesterol storage 4.656934e-3
GO:0008016 regulation of heart contraction 4.671635e-3
GO:0008612 peptidyl-lysine modification to hypusine 4.677911e-3
GO:0006576 cellular biogenic amine metabolic process 4.756013e-3
GO:0035444 nickel ion transmembrane transport 4.760107e-3
GO:0070932 histone H3 deacetylation 4.760107e-3
GO:0009313 oligosaccharide catabolic process 4.760107e-3
GO:0002697 regulation of immune effector process 4.786010e-3
GO:0072376 protein activation cascade 4.830383e-3
GO:2000107 negative regulation of leukocyte apoptosis 4.841981e-3
GO:0045619 regulation of lymphocyte differentiation 5.016872e-3
GO:0045087 innate immune response 5.047691e-3
GO:0009649 entrainment of circadian clock 5.098721e-3
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 5.161543e-3
GO:0034654 nucleobase-containing compound biosynthetic process 5.175232e-3
GO:0006689 ganglioside catabolic process 5.307607e-3
GO:0006695 cholesterol biosynthetic process 5.361145e-3
GO:0010226 response to lithium ion 5.404167e-3
GO:0071577 zinc ion transmembrane transport 5.444616e-3
GO:0032732 positive regulation of interleukin-1 production 5.528886e-3
GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade 5.579745e-3
GO:0015991 ATP hydrolysis coupled proton transport 5.597423e-3
GO:0010884 positive regulation of lipid storage 5.597423e-3
GO:0051928 positive regulation of calcium ion transport 5.636520e-3
GO:0044130 negative regulation of growth of symbiont in host 5.653911e-3
GO:0002540 leukotriene production involved in inflammatory response 5.798455e-3
GO:0006739 NADP metabolic process 5.807903e-3
GO:0034377 plasma lipoprotein particle assembly 5.848414e-3
GO:0030157 pancreatic juice secretion 5.866328e-3
GO:0046684 response to pyrethroid 5.866328e-3
GO:0002768 immune response-regulating cell surface receptor signaling pathway 5.879610e-3
GO:0071394 cellular response to testosterone stimulus 5.883362e-3
GO:0008535 respiratory chain complex IV assembly 5.929843e-3
GO:0034372 very-low-density lipoprotein particle remodeling 5.993744e-3
GO:0030497 fatty acid elongation 6.045463e-3
GO:0015684 ferrous iron transport 6.078634e-3
GO:0001765 membrane raft assembly 6.078634e-3
GO:0045332 phospholipid translocation 6.195184e-3
GO:0051606 detection of stimulus 6.284539e-3
GO:0009236 cobalamin biosynthetic process 6.296885e-3
GO:0015939 pantothenate metabolic process 6.296885e-3
GO:0001309 age-dependent telomere shortening 6.296885e-3
GO:0006409 tRNA export from nucleus 6.296885e-3
GO:0000115 regulation of transcription involved in S phase of mitotic cell cycle 6.296885e-3
GO:0009581 detection of external stimulus 6.356952e-3
GO:0042866 pyruvate biosynthetic process 6.470220e-3
GO:0033121 regulation of purine nucleotide catabolic process 6.479302e-3
GO:0007522 visceral muscle development 6.489641e-3