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Novel motif:80

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name:motif80_CTCTGAGAGAA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0002684 positive regulation of immune system process 1.245783e-19
GO:0002694 regulation of leukocyte activation 8.453855e-19
GO:0051249 regulation of lymphocyte activation 2.032633e-18
GO:0050865 regulation of cell activation 2.695439e-18
GO:0006954 inflammatory response 3.447635e-17
GO:0006952 defense response 4.332402e-16
GO:0032757 positive regulation of interleukin-8 production 1.372406e-15
GO:0050896 response to stimulus 1.900053e-15
GO:0002696 positive regulation of leukocyte activation 3.317499e-15
GO:0050789 regulation of biological process 6.077914e-15
GO:0050867 positive regulation of cell activation 6.962142e-15
GO:0050863 regulation of T cell activation 7.940664e-15
GO:0032103 positive regulation of response to external stimulus 1.227455e-14
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1.236948e-14
GO:0051251 positive regulation of lymphocyte activation 6.381776e-14
GO:0051716 cellular response to stimulus 1.160174e-13
GO:0002376 immune system process 1.397223e-13
GO:0048584 positive regulation of response to stimulus 1.660470e-13
GO:0065007 biological regulation 4.388029e-13
GO:0050778 positive regulation of immune response 7.615781e-13
GO:0050794 regulation of cellular process 8.450537e-13
GO:0048583 regulation of response to stimulus 9.234657e-13
GO:0046709 IDP catabolic process 1.051943e-12
GO:0046032 ADP catabolic process 1.051943e-12
GO:0050727 regulation of inflammatory response 1.195710e-12
GO:0031349 positive regulation of defense response 1.663404e-12
GO:0031442 positive regulation of mRNA 3'-end processing 2.500376e-12
GO:0050870 positive regulation of T cell activation 3.435436e-12
GO:0050729 positive regulation of inflammatory response 4.750179e-12
GO:0002682 regulation of immune system process 8.335605e-12
GO:0031440 regulation of mRNA 3'-end processing 1.055598e-11
GO:0080134 regulation of response to stress 2.717471e-11
GO:0061014 positive regulation of mRNA catabolic process 2.781065e-11
GO:0032880 regulation of protein localization 5.126339e-11
GO:0006955 immune response 8.025659e-11
GO:0050776 regulation of immune response 8.849260e-11
GO:0007165 signal transduction 1.007319e-10
GO:0019216 regulation of lipid metabolic process 2.663451e-10
GO:0002526 acute inflammatory response 3.123034e-10
GO:0015889 cobalamin transport 3.674666e-10
GO:0009181 purine ribonucleoside diphosphate catabolic process 6.755795e-10
GO:0031347 regulation of defense response 7.277288e-10
GO:0030595 leukocyte chemotaxis 7.984017e-10
GO:0042493 response to drug 8.266300e-10
GO:0045321 leukocyte activation 9.540270e-10
GO:0032101 regulation of response to external stimulus 1.078410e-9
GO:0009595 detection of biotic stimulus 1.166180e-9
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 2.208883e-9
GO:0034114 regulation of heterotypic cell-cell adhesion 2.208883e-9
GO:0042993 positive regulation of transcription factor import into nucleus 3.491047e-9
GO:0023052 signaling 3.979466e-9
GO:0007166 cell surface receptor linked signaling pathway 4.943510e-9
GO:0007155 cell adhesion 5.045888e-9
GO:0048518 positive regulation of biological process 8.388423e-9
GO:0002253 activation of immune response 8.724397e-9
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 9.003800e-9
GO:0046649 lymphocyte activation 1.266377e-8
GO:0001910 regulation of leukocyte mediated cytotoxicity 1.491470e-8
GO:0009611 response to wounding 1.642191e-8
GO:0045834 positive regulation of lipid metabolic process 1.722367e-8
GO:0009191 ribonucleoside diphosphate catabolic process 1.848636e-8
GO:0042110 T cell activation 1.902539e-8
GO:0060326 cell chemotaxis 2.113262e-8
GO:0007154 cell communication 2.168868e-8
GO:0032874 positive regulation of stress-activated MAPK cascade 2.755607e-8
GO:0061013 regulation of mRNA catabolic process 3.360987e-8
GO:0002439 chronic inflammatory response to antigenic stimulus 3.395138e-8
GO:0016576 histone dephosphorylation 4.678645e-8
GO:0042346 positive regulation of NF-kappaB import into nucleus 4.841960e-8
GO:0034605 cellular response to heat 5.167277e-8
GO:0030324 lung development 5.282654e-8
GO:0030593 neutrophil chemotaxis 5.298323e-8
GO:0070163 regulation of adiponectin secretion 5.746278e-8
GO:0045216 cell-cell junction organization 6.118558e-8
GO:0031295 T cell costimulation 6.576850e-8
GO:0006953 acute-phase response 7.548784e-8
GO:0001660 fever generation 8.124619e-8
GO:0009607 response to biotic stimulus 8.248572e-8
GO:0014050 negative regulation of glutamate secretion 8.532794e-8
GO:0071637 regulation of monocyte chemotactic protein-1 production 8.871595e-8
GO:0032677 regulation of interleukin-8 production 9.638890e-8
GO:0034330 cell junction organization 1.013400e-7
GO:0070372 regulation of ERK1 and ERK2 cascade 1.044659e-7
GO:0048745 smooth muscle tissue development 1.055566e-7
GO:0072277 metanephric glomerular capillary formation 1.094489e-7
GO:0050685 positive regulation of mRNA processing 1.125523e-7
GO:0071726 cellular response to diacyl bacterial lipopeptide 1.329604e-7
GO:0042496 detection of diacyl bacterial lipopeptide 1.329604e-7
GO:0045086 positive regulation of interleukin-2 biosynthetic process 1.680079e-7
GO:0070164 negative regulation of adiponectin secretion 1.695607e-7
GO:0060355 positive regulation of cell adhesion molecule production 1.695607e-7
GO:0035505 positive regulation of myosin light chain kinase activity 1.695607e-7
GO:0072104 glomerular capillary formation 1.749502e-7
GO:0032728 positive regulation of interferon-beta production 1.789041e-7
GO:0030323 respiratory tube development 1.905035e-7
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1.969754e-7
GO:0009605 response to external stimulus 2.013978e-7
GO:0045089 positive regulation of innate immune response 2.247930e-7
GO:0032735 positive regulation of interleukin-12 production 2.313961e-7
GO:0051707 response to other organism 2.559294e-7
GO:0002673 regulation of acute inflammatory response 2.577677e-7
GO:0034764 positive regulation of transmembrane transport 2.588723e-7
GO:0030155 regulation of cell adhesion 3.168088e-7
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 3.174049e-7
GO:0051930 regulation of sensory perception of pain 3.451674e-7
GO:0002764 immune response-regulating signaling pathway 3.457561e-7
GO:0045076 regulation of interleukin-2 biosynthetic process 3.902189e-7
GO:0010627 regulation of intracellular protein kinase cascade 4.006444e-7
GO:0010740 positive regulation of intracellular protein kinase cascade 4.211198e-7
GO:0010470 regulation of gastrulation 4.383151e-7
GO:0007181 transforming growth factor beta receptor complex assembly 4.835411e-7
GO:0009966 regulation of signal transduction 4.849393e-7
GO:0043410 positive regulation of MAPKKK cascade 4.940662e-7
GO:0034123 positive regulation of toll-like receptor signaling pathway 5.074996e-7
GO:0007565 female pregnancy 5.814648e-7
GO:0006950 response to stress 5.857500e-7
GO:0048522 positive regulation of cellular process 6.022394e-7
GO:0009386 translational attenuation 6.724137e-7
GO:0045940 positive regulation of steroid metabolic process 7.325774e-7
GO:0031341 regulation of cell killing 7.680922e-7
GO:0032648 regulation of interferon-beta production 8.005344e-7
GO:0002544 chronic inflammatory response 8.608491e-7
GO:0051050 positive regulation of transport 8.660024e-7
GO:0002709 regulation of T cell mediated immunity 8.799682e-7
GO:0072224 metanephric glomerulus development 9.133495e-7
GO:0016045 detection of bacterium 9.133495e-7
GO:0070663 regulation of leukocyte proliferation 9.489103e-7
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 9.587509e-7
GO:0046889 positive regulation of lipid biosynthetic process 9.777518e-7
GO:0045088 regulation of innate immune response 9.915295e-7
GO:0035690 cellular response to drug 1.028875e-6
GO:0002757 immune response-activating signal transduction 1.064568e-6
GO:0002706 regulation of lymphocyte mediated immunity 1.191078e-6
GO:2000193 positive regulation of fatty acid transport 1.224859e-6
GO:0044060 regulation of endocrine process 1.263103e-6
GO:0071670 smooth muscle cell chemotaxis 1.319873e-6
GO:0060981 cell migration involved in coronary angiogenesis 1.319873e-6
GO:0000255 allantoin metabolic process 1.326141e-6
GO:0008037 cell recognition 1.360094e-6
GO:0008283 cell proliferation 1.441776e-6
GO:0002440 production of molecular mediator of immune response 1.455489e-6
GO:0070542 response to fatty acid 1.487595e-6
GO:0070340 detection of bacterial lipopeptide 1.567032e-6
GO:0002699 positive regulation of immune effector process 1.650822e-6
GO:0070201 regulation of establishment of protein localization 1.691344e-6
GO:0010193 response to ozone 1.803096e-6
GO:0010535 positive regulation of activation of JAK2 kinase activity 1.839524e-6
GO:0032608 interferon-beta production 1.868327e-6
GO:0030730 sequestering of triglyceride 2.002843e-6
GO:0032872 regulation of stress-activated MAPK cascade 2.214992e-6
GO:0008284 positive regulation of cell proliferation 2.227898e-6
GO:0002708 positive regulation of lymphocyte mediated immunity 2.439217e-6
GO:0071727 cellular response to triacyl bacterial lipopeptide 2.443118e-6
GO:0042495 detection of triacyl bacterial lipopeptide 2.443118e-6
GO:0021858 GABAergic neuron differentiation in basal ganglia 2.708724e-6
GO:0009988 cell-cell recognition 2.854952e-6
GO:0042063 gliogenesis 2.972535e-6
GO:0032663 regulation of interleukin-2 production 3.003270e-6
GO:0032944 regulation of mononuclear cell proliferation 3.098092e-6
GO:0070374 positive regulation of ERK1 and ERK2 cascade 3.376421e-6
GO:0042744 hydrogen peroxide catabolic process 3.386562e-6
GO:0001967 suckling behavior 3.453508e-6
GO:0032308 positive regulation of prostaglandin secretion 3.484839e-6
GO:0051272 positive regulation of cellular component movement 3.733473e-6
GO:0008306 associative learning 3.885931e-6
GO:0042990 regulation of transcription factor import into nucleus 4.170803e-6
GO:0070665 positive regulation of leukocyte proliferation 4.206985e-6
GO:0002703 regulation of leukocyte mediated immunity 4.403427e-6
GO:0050900 leukocyte migration 4.431347e-6
GO:0015893 drug transport 4.519562e-6
GO:0032879 regulation of localization 4.564620e-6
GO:0002675 positive regulation of acute inflammatory response 4.733852e-6
GO:0032675 regulation of interleukin-6 production 4.757179e-6
GO:0042178 xenobiotic catabolic process 4.975447e-6
GO:0002820 negative regulation of adaptive immune response 5.321941e-6
GO:0035295 tube development 5.523911e-6
GO:0032892 positive regulation of organic acid transport 5.725586e-6
GO:0043408 regulation of MAPKKK cascade 5.758414e-6
GO:0023051 regulation of signaling 6.058121e-6
GO:0042129 regulation of T cell proliferation 6.155668e-6
GO:0032946 positive regulation of mononuclear cell proliferation 6.517348e-6
GO:0050670 regulation of lymphocyte proliferation 6.929451e-6
GO:0040017 positive regulation of locomotion 6.958245e-6
GO:0009617 response to bacterium 7.033463e-6
GO:0042221 response to chemical stimulus 7.066738e-6
GO:0016998 cell wall macromolecule catabolic process 7.099537e-6
GO:0032760 positive regulation of tumor necrosis factor production 7.353923e-6
GO:0033523 histone H2B ubiquitination 7.498631e-6
GO:0045087 innate immune response 7.703144e-6
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 7.782506e-6
GO:0020028 hemoglobin import 7.855297e-6
GO:0002449 lymphocyte mediated immunity 7.912937e-6
GO:0032481 positive regulation of type I interferon production 8.784138e-6
GO:0016477 cell migration 8.996745e-6
GO:0010646 regulation of cell communication 9.149451e-6
GO:0051240 positive regulation of multicellular organismal process 9.177344e-6
GO:0032370 positive regulation of lipid transport 9.339357e-6
GO:0090030 regulation of steroid hormone biosynthetic process 9.790917e-6
GO:0001771 immunological synapse formation 1.009447e-5
GO:0010647 positive regulation of cell communication 1.050109e-5
GO:0014826 vein smooth muscle contraction 1.055811e-5
GO:0030091 protein repair 1.092261e-5
GO:0032733 positive regulation of interleukin-10 production 1.099745e-5
GO:0044036 cell wall macromolecule metabolic process 1.174219e-5
GO:0034116 positive regulation of heterotypic cell-cell adhesion 1.193478e-5
GO:0046890 regulation of lipid biosynthetic process 1.205293e-5
GO:0002437 inflammatory response to antigenic stimulus 1.225716e-5
GO:0023056 positive regulation of signaling 1.244378e-5
GO:0045410 positive regulation of interleukin-6 biosynthetic process 1.317095e-5
GO:2000465 regulation of glycogen (starch) synthase activity 1.326901e-5
GO:0009410 response to xenobiotic stimulus 1.326928e-5
GO:2000147 positive regulation of cell motility 1.396541e-5
GO:0032490 detection of molecule of bacterial origin 1.397118e-5
GO:0002697 regulation of immune effector process 1.402324e-5
GO:0051222 positive regulation of protein transport 1.419422e-5
GO:0006629 lipid metabolic process 1.472258e-5
GO:0050671 positive regulation of lymphocyte proliferation 1.583778e-5
GO:0050996 positive regulation of lipid catabolic process 1.589023e-5
GO:0006805 xenobiotic metabolic process 1.628540e-5
GO:0045058 T cell selection 1.645011e-5
GO:0051223 regulation of protein transport 1.651373e-5
GO:0014821 phasic smooth muscle contraction 1.689030e-5
GO:0034329 cell junction assembly 1.701203e-5
GO:0018108 peptidyl-tyrosine phosphorylation 1.744470e-5
GO:0010893 positive regulation of steroid biosynthetic process 1.760049e-5
GO:0032355 response to estradiol stimulus 1.830575e-5
GO:0042269 regulation of natural killer cell mediated cytotoxicity 1.831971e-5
GO:0030335 positive regulation of cell migration 1.905466e-5
GO:0071466 cellular response to xenobiotic stimulus 1.914193e-5
GO:0043687 post-translational protein modification 1.940660e-5
GO:0051345 positive regulation of hydrolase activity 1.987975e-5
GO:0001775 cell activation 2.074593e-5
GO:0009967 positive regulation of signal transduction 2.137001e-5
GO:0034201 response to oleic acid 2.166847e-5
GO:2000191 regulation of fatty acid transport 2.177495e-5
GO:0031343 positive regulation of cell killing 2.189452e-5
GO:0030098 lymphocyte differentiation 2.196982e-5
GO:0032741 positive regulation of interleukin-18 production 2.320965e-5
GO:0060479 lung cell differentiation 2.336600e-5
GO:0042307 positive regulation of protein import into nucleus 2.458319e-5
GO:0070301 cellular response to hydrogen peroxide 2.465186e-5
GO:0051336 regulation of hydrolase activity 2.479712e-5
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 2.535124e-5
GO:0016046 detection of fungus 2.535124e-5
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 2.535124e-5
GO:0051302 regulation of cell division 2.554400e-5
GO:0035645 enteric smooth muscle cell differentiation 2.583064e-5
GO:0051602 response to electrical stimulus 2.588509e-5
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 2.603643e-5
GO:0030855 epithelial cell differentiation 2.656582e-5
GO:0060745 mammary gland branching involved in pregnancy 2.797270e-5
GO:0034115 negative regulation of heterotypic cell-cell adhesion 2.902628e-5
GO:0071221 cellular response to bacterial lipopeptide 2.976986e-5
GO:0034121 regulation of toll-like receptor signaling pathway 2.978677e-5
GO:0034767 positive regulation of ion transmembrane transport 3.008383e-5
GO:0033566 gamma-tubulin complex localization 3.011686e-5
GO:0007566 embryo implantation 3.051301e-5
GO:0051270 regulation of cellular component movement 3.077136e-5
GO:0043462 regulation of ATPase activity 3.259345e-5
GO:0048013 ephrin receptor signaling pathway 3.275601e-5
GO:0032386 regulation of intracellular transport 3.288497e-5
GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway 3.312873e-5
GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production 3.312873e-5
GO:0032738 positive regulation of interleukin-15 production 3.312873e-5
GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade 3.375708e-5
GO:0033127 regulation of histone phosphorylation 3.502513e-5
GO:0009791 post-embryonic development 3.539491e-5
GO:2000178 negative regulation of neural precursor cell proliferation 3.561441e-5
GO:0018212 peptidyl-tyrosine modification 3.643176e-5
GO:0001659 temperature homeostasis 3.730552e-5
GO:0032543 mitochondrial translation 3.762120e-5
GO:0050921 positive regulation of chemotaxis 3.774183e-5
GO:0008272 sulfate transport 3.837240e-5
GO:0043603 cellular amide metabolic process 3.930859e-5
GO:0033993 response to lipid 4.335334e-5
GO:0045879 negative regulation of smoothened signaling pathway 4.390583e-5
GO:0002819 regulation of adaptive immune response 4.403535e-5
GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response 4.509653e-5
GO:0072239 metanephric glomerulus vasculature development 4.548136e-5
GO:0043085 positive regulation of catalytic activity 4.627033e-5
GO:0032501 multicellular organismal process 4.656116e-5
GO:0009987 cellular process 4.733908e-5
GO:0019477 L-lysine catabolic process 4.812908e-5
GO:0006911 phagocytosis, engulfment 4.931008e-5
GO:2001022 positive regulation of response to DNA damage stimulus 4.981383e-5
GO:0006349 regulation of gene expression by genetic imprinting 5.055571e-5
GO:0032722 positive regulation of chemokine production 5.218824e-5
GO:0051135 positive regulation of NK T cell activation 5.230138e-5
GO:0014070 response to organic cyclic compound 5.232133e-5
GO:0009649 entrainment of circadian clock 5.369752e-5
GO:0030728 ovulation 5.443709e-5
GO:0050715 positive regulation of cytokine secretion 5.683988e-5
GO:0019218 regulation of steroid metabolic process 5.792113e-5
GO:0048520 positive regulation of behavior 5.886408e-5
GO:0060487 lung epithelial cell differentiation 5.926983e-5
GO:0033129 positive regulation of histone phosphorylation 6.335094e-5
GO:0042345 regulation of NF-kappaB import into nucleus 6.497231e-5
GO:0033077 T cell differentiation in thymus 6.539852e-5
GO:0030217 T cell differentiation 6.559183e-5
GO:0032715 negative regulation of interleukin-6 production 6.615727e-5
GO:0032496 response to lipopolysaccharide 6.814893e-5
GO:0051049 regulation of transport 6.848373e-5
GO:0060429 epithelium development 6.894215e-5
GO:0007252 I-kappaB phosphorylation 6.952726e-5
GO:0060541 respiratory system development 7.235007e-5
GO:0006083 acetate metabolic process 7.417603e-5
GO:0070309 lens fiber cell morphogenesis 7.603828e-5
GO:0032661 regulation of interleukin-18 production 7.603828e-5
GO:0014829 vascular smooth muscle contraction 7.632761e-5
GO:0061138 morphogenesis of a branching epithelium 7.703934e-5
GO:0043255 regulation of carbohydrate biosynthetic process 8.425592e-5
GO:0002377 immunoglobulin production 8.506792e-5
GO:0002521 leukocyte differentiation 8.517978e-5
GO:0051238 sequestering of metal ion 8.791129e-5
GO:0042127 regulation of cell proliferation 8.818441e-5
GO:0030201 heparan sulfate proteoglycan metabolic process 8.877020e-5
GO:0001819 positive regulation of cytokine production 9.018750e-5
GO:0032388 positive regulation of intracellular transport 9.297054e-5
GO:0071223 cellular response to lipoteichoic acid 9.499625e-5
GO:0048246 macrophage chemotaxis 9.623587e-5
GO:0048585 negative regulation of response to stimulus 9.641923e-5
GO:0050714 positive regulation of protein secretion 9.709539e-5
GO:0007095 mitotic cell cycle G2/M transition DNA damage checkpoint 9.815333e-5
GO:0002088 lens development in camera-type eye 9.835009e-5
GO:0050777 negative regulation of immune response 9.925107e-5
GO:0042743 hydrogen peroxide metabolic process 1.008475e-4
GO:0032755 positive regulation of interleukin-6 production 1.058621e-4
GO:2000736 regulation of stem cell differentiation 1.059202e-4
GO:0090398 cellular senescence 1.087284e-4
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 1.096533e-4
GO:2000756 regulation of peptidyl-lysine acetylation 1.102481e-4
GO:0048008 platelet-derived growth factor receptor signaling pathway 1.110903e-4
GO:0002711 positive regulation of T cell mediated immunity 1.123756e-4
GO:0046323 glucose import 1.163690e-4
GO:0007497 posterior midgut development 1.163690e-4
GO:2000278 regulation of DNA biosynthetic process 1.202265e-4
GO:0045619 regulation of lymphocyte differentiation 1.202909e-4
GO:0034332 adherens junction organization 1.208403e-4
GO:0046688 response to copper ion 1.216189e-4
GO:0009888 tissue development 1.241174e-4
GO:0008211 glucocorticoid metabolic process 1.269976e-4
GO:0045580 regulation of T cell differentiation 1.296187e-4
GO:0070593 dendrite self-avoidance 1.312369e-4
GO:0048870 cell motility 1.328705e-4
GO:0002639 positive regulation of immunoglobulin production 1.342477e-4
GO:0032655 regulation of interleukin-12 production 1.342689e-4
GO:0043627 response to estrogen stimulus 1.347295e-4
GO:0090316 positive regulation of intracellular protein transport 1.373346e-4
GO:0002237 response to molecule of bacterial origin 1.374390e-4
GO:0009628 response to abiotic stimulus 1.388122e-4
GO:0032680 regulation of tumor necrosis factor production 1.393742e-4
GO:0001543 ovarian follicle rupture 1.441797e-4
GO:0055080 cation homeostasis 1.488564e-4
GO:0014048 regulation of glutamate secretion 1.497207e-4
GO:0034629 cellular protein complex localization 1.529786e-4
GO:0032729 positive regulation of interferon-gamma production 1.539975e-4
GO:0032700 negative regulation of interleukin-17 production 1.540418e-4
GO:0016064 immunoglobulin mediated immune response 1.542014e-4
GO:0044093 positive regulation of molecular function 1.577782e-4
GO:0071157 negative regulation of cell cycle arrest 1.578703e-4
GO:0046330 positive regulation of JNK cascade 1.579251e-4
GO:0045726 positive regulation of integrin biosynthetic process 1.625335e-4
GO:0046824 positive regulation of nucleocytoplasmic transport 1.639821e-4
GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane 1.649819e-4
GO:0048790 maintenance of presynaptic active zone structure 1.649819e-4
GO:0002355 detection of tumor cell 1.649819e-4
GO:0019227 neuronal action potential propagation 1.651132e-4
GO:0048541 Peyer's patch development 1.652169e-4
GO:0042742 defense response to bacterium 1.655518e-4
GO:0042443 phenylethylamine metabolic process 1.703524e-4
GO:0042997 negative regulation of Golgi to plasma membrane protein transport 1.715614e-4
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 1.737836e-4
GO:0033033 negative regulation of myeloid cell apoptosis 1.822760e-4
GO:0033211 adiponectin-mediated signaling pathway 1.825736e-4
GO:0032387 negative regulation of intracellular transport 1.840955e-4
GO:0051704 multi-organism process 1.881318e-4
GO:0007174 epidermal growth factor catabolic process 1.887188e-4
GO:0008219 cell death 1.898273e-4
GO:0014066 regulation of phosphatidylinositol 3-kinase cascade 1.907689e-4
GO:0002218 activation of innate immune response 1.970794e-4
GO:0051781 positive regulation of cell division 1.985082e-4
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 1.990836e-4
GO:0035065 regulation of histone acetylation 1.998621e-4
GO:0042306 regulation of protein import into nucleus 2.025222e-4
GO:0050728 negative regulation of inflammatory response 2.084771e-4
GO:0042520 positive regulation of tyrosine phosphorylation of Stat4 protein 2.122291e-4
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 2.122291e-4
GO:0050920 regulation of chemotaxis 2.141200e-4
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 2.141565e-4
GO:0046449 creatinine metabolic process 2.142206e-4
GO:0048754 branching morphogenesis of a tube 2.200421e-4
GO:0033157 regulation of intracellular protein transport 2.208328e-4
GO:0009266 response to temperature stimulus 2.337324e-4
GO:0032368 regulation of lipid transport 2.355708e-4
GO:0019724 B cell mediated immunity 2.359161e-4
GO:0001914 regulation of T cell mediated cytotoxicity 2.453843e-4
GO:0048015 phosphatidylinositol-mediated signaling 2.458486e-4
GO:2000467 positive regulation of glycogen (starch) synthase activity 2.531542e-4
GO:0010536 positive regulation of activation of Janus kinase activity 2.537268e-4
GO:0042102 positive regulation of T cell proliferation 2.665461e-4
GO:0060341 regulation of cellular localization 2.682435e-4
GO:0002329 pre-B cell differentiation 2.791308e-4
GO:0035247 peptidyl-arginine omega-N-methylation 2.796762e-4
GO:0040012 regulation of locomotion 2.832949e-4
GO:2000758 positive regulation of peptidyl-lysine acetylation 2.860738e-4
GO:0007162 negative regulation of cell adhesion 2.882590e-4
GO:0030334 regulation of cell migration 2.890124e-4
GO:0034103 regulation of tissue remodeling 2.896966e-4
GO:0006069 ethanol oxidation 2.937015e-4
GO:0033026 negative regulation of mast cell apoptosis 2.938442e-4
GO:0016265 death 3.019212e-4
GO:0009620 response to fungus 3.041624e-4
GO:0002252 immune effector process 3.089297e-4
GO:0050829 defense response to Gram-negative bacterium 3.114942e-4
GO:0061290 canonical Wnt receptor signaling pathway involved in metanephric kidney development 3.141784e-4
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 3.166471e-4
GO:0007009 plasma membrane organization 3.183829e-4
GO:0006880 intracellular sequestering of iron ion 3.196108e-4
GO:0050790 regulation of catalytic activity 3.231002e-4
GO:0009101 glycoprotein biosynthetic process 3.280716e-4
GO:0002426 immunoglobulin production in mucosal tissue 3.281626e-4
GO:0010001 glial cell differentiation 3.299862e-4
GO:0010693 negative regulation of alkaline phosphatase activity 3.371152e-4
GO:0002282 microglial cell activation involved in immune response 3.469957e-4
GO:0051145 smooth muscle cell differentiation 3.480588e-4
GO:0080135 regulation of cellular response to stress 3.516066e-4
GO:2000036 regulation of stem cell maintenance 3.569003e-4
GO:0002839 positive regulation of immune response to tumor cell 3.597425e-4
GO:0006487 protein N-linked glycosylation 3.653224e-4
GO:0009408 response to heat 3.709692e-4
GO:2000145 regulation of cell motility 3.719127e-4
GO:0050707 regulation of cytokine secretion 3.850872e-4
GO:0007549 dosage compensation 3.892390e-4
GO:0060416 response to growth hormone stimulus 3.903569e-4
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade 3.913090e-4
GO:0030259 lipid glycosylation 3.947220e-4
GO:0015914 phospholipid transport 3.974517e-4
GO:0070207 protein homotrimerization 3.981713e-4
GO:2000171 negative regulation of dendrite development 3.985958e-4
GO:0070127 tRNA aminoacylation for mitochondrial protein translation 4.051419e-4
GO:2000836 positive regulation of androgen secretion 4.051419e-4
GO:2000500 positive regulation of induction of apoptosis in response to chemical stimulus 4.051419e-4
GO:0060236 regulation of mitotic spindle organization 4.051419e-4
GO:0001982 baroreceptor response to decreased systemic arterial blood pressure 4.051419e-4
GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis 4.051922e-4
GO:0048286 lung alveolus development 4.078302e-4
GO:0051769 regulation of nitric-oxide synthase biosynthetic process 4.084183e-4
GO:0002669 positive regulation of T cell anergy 4.086266e-4
GO:0014909 smooth muscle cell migration 4.121639e-4
GO:0022603 regulation of anatomical structure morphogenesis 4.168904e-4
GO:0033591 response to L-ascorbic acid 4.264547e-4
GO:0050708 regulation of protein secretion 4.348062e-4
GO:0048537 mucosal-associated lymphoid tissue development 4.393209e-4
GO:0002230 positive regulation of defense response to virus by host 4.405547e-4
GO:0035066 positive regulation of histone acetylation 4.428570e-4
GO:0051128 regulation of cellular component organization 4.451375e-4
GO:0008347 glial cell migration 4.476986e-4
GO:0071624 positive regulation of granulocyte chemotaxis 4.542306e-4
GO:0019428 allantoin biosynthetic process 4.542306e-4
GO:0032328 alanine transport 4.557948e-4
GO:0050926 regulation of positive chemotaxis 4.578453e-4
GO:0051047 positive regulation of secretion 4.596355e-4
GO:0030258 lipid modification 4.638816e-4
GO:0045785 positive regulation of cell adhesion 4.646858e-4
GO:0033032 regulation of myeloid cell apoptosis 4.679111e-4
GO:0012501 programmed cell death 4.863495e-4
GO:0014012 peripheral nervous system axon regeneration 4.865897e-4
GO:0060135 maternal process involved in female pregnancy 4.929479e-4
GO:0007156 homophilic cell adhesion 4.966737e-4
GO:0002710 negative regulation of T cell mediated immunity 4.992844e-4
GO:0010243 response to organic nitrogen 5.036015e-4
GO:0006855 drug transmembrane transport 5.250511e-4
GO:0034454 microtubule anchoring at centrosome 5.296666e-4
GO:0040011 locomotion 5.350376e-4
GO:0045582 positive regulation of T cell differentiation 5.385524e-4
GO:0071514 genetic imprinting 5.406631e-4
GO:0070257 positive regulation of mucus secretion 5.446127e-4
GO:0005989 lactose biosynthetic process 5.446127e-4
GO:0071780 mitotic cell cycle G2/M transition checkpoint 5.448633e-4
GO:0018279 protein N-linked glycosylation via asparagine 5.499684e-4
GO:0072102 glomerulus morphogenesis 5.502565e-4
GO:0043550 regulation of lipid kinase activity 5.632543e-4
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 5.722257e-4
GO:0031329 regulation of cellular catabolic process 5.774018e-4
GO:0072210 metanephric nephron development 5.890014e-4
GO:0051494 negative regulation of cytoskeleton organization 6.032527e-4
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 6.067778e-4
GO:0048523 negative regulation of cellular process 6.106297e-4
GO:0032781 positive regulation of ATPase activity 6.147079e-4
GO:0032367 intracellular cholesterol transport 6.148332e-4
GO:0032647 regulation of interferon-alpha production 6.209338e-4
GO:0014805 smooth muscle adaptation 6.209338e-4
GO:0045113 regulation of integrin biosynthetic process 6.210851e-4
GO:0046544 development of secondary male sexual characteristics 6.469006e-4
GO:0007601 visual perception 6.484879e-4
GO:0051016 barbed-end actin filament capping 6.548835e-4
GO:0070085 glycosylation 6.592713e-4
GO:0043242 negative regulation of protein complex disassembly 6.814868e-4
GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification 6.832262e-4
GO:0065008 regulation of biological quality 6.868920e-4


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0009605 response to external stimulus 8.248572e-15
GO:0050896 response to stimulus 1.810927e-13
GO:0002252 immune effector process 6.736472e-13
GO:0051704 multi-organism process 1.163459e-12
GO:0006955 immune response 8.960929e-12
GO:0002443 leukocyte mediated immunity 1.051069e-11
GO:0042221 response to chemical stimulus 1.176168e-11
GO:0009617 response to bacterium 2.134715e-11
GO:0051707 response to other organism 3.243943e-11
GO:0016064 immunoglobulin mediated immune response 4.147130e-11
GO:0019724 B cell mediated immunity 4.438112e-11
GO:0035645 enteric smooth muscle cell differentiation 1.183310e-10
GO:0007497 posterior midgut development 1.183310e-10
GO:0002376 immune system process 1.472516e-10
GO:0010822 positive regulation of mitochondrion organization 1.621725e-10
GO:0009607 response to biotic stimulus 4.118529e-10
GO:0050727 regulation of inflammatory response 7.685553e-10
GO:0019362 pyridine nucleotide metabolic process 9.272420e-10
GO:0031667 response to nutrient levels 1.493303e-9
GO:0046496 nicotinamide nucleotide metabolic process 1.748381e-9
GO:0007584 response to nutrient 1.827805e-9
GO:0061162 establishment of monopolar cell polarity 2.414633e-9
GO:0006959 humoral immune response 3.037588e-9
GO:0090200 positive regulation of release of cytochrome c from mitochondria 3.192750e-9
GO:0010033 response to organic substance 3.208348e-9
GO:0044130 negative regulation of growth of symbiont in host 3.707595e-9
GO:0010867 positive regulation of triglyceride biosynthetic process 7.866472e-9
GO:0032355 response to estradiol stimulus 8.944124e-9
GO:0009991 response to extracellular stimulus 1.091490e-8
GO:0050776 regulation of immune response 1.414075e-8
GO:0032846 positive regulation of homeostatic process 1.439712e-8
GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 1.593447e-8
GO:0003008 system process 2.229734e-8
GO:0048585 negative regulation of response to stimulus 2.233667e-8
GO:0002035 brain renin-angiotensin system 2.263445e-8
GO:0035419 activation of MAPK activity involved in innate immune response 2.310997e-8
GO:0014043 negative regulation of neuron maturation 2.402404e-8
GO:0032733 positive regulation of interleukin-10 production 3.229137e-8
GO:0032879 regulation of localization 3.286037e-8
GO:0002682 regulation of immune system process 3.604809e-8
GO:0022407 regulation of cell-cell adhesion 3.647712e-8
GO:0032496 response to lipopolysaccharide 3.741475e-8
GO:0031915 positive regulation of synaptic plasticity 3.844613e-8
GO:0043627 response to estrogen stimulus 3.928827e-8
GO:0030183 B cell differentiation 4.106595e-8
GO:0006733 oxidoreduction coenzyme metabolic process 4.201747e-8
GO:0051915 induction of synaptic plasticity by chemical substance 5.197410e-8
GO:0048545 response to steroid hormone stimulus 6.542781e-8
GO:0002830 positive regulation of type 2 immune response 8.447470e-8
GO:0019441 tryptophan catabolic process to kynurenine 9.177304e-8
GO:0002377 immunoglobulin production 1.018850e-7
GO:0002237 response to molecule of bacterial origin 1.046006e-7
GO:0002449 lymphocyte mediated immunity 1.081963e-7
GO:0030595 leukocyte chemotaxis 1.145499e-7
GO:0002016 regulation of blood volume by renin-angiotensin 1.159111e-7
GO:0048676 axon extension involved in development 1.548407e-7
GO:0051901 positive regulation of mitochondrial depolarization 1.711241e-7
GO:0050778 positive regulation of immune response 1.947047e-7
GO:0046483 heterocycle metabolic process 1.984147e-7
GO:0042113 B cell activation 2.104421e-7
GO:0006952 defense response 2.705114e-7
GO:0006568 tryptophan metabolic process 2.793792e-7
GO:0002440 production of molecular mediator of immune response 3.067865e-7
GO:0032653 regulation of interleukin-10 production 3.105822e-7
GO:0002253 activation of immune response 3.209156e-7
GO:0017085 response to insecticide 3.419334e-7
GO:0051384 response to glucocorticoid stimulus 3.561446e-7
GO:0042742 defense response to bacterium 3.860728e-7
GO:0003013 circulatory system process 4.088590e-7
GO:0019674 NAD metabolic process 4.207237e-7
GO:0043901 negative regulation of multi-organism process 4.519053e-7
GO:0051049 regulation of transport 5.277398e-7
GO:0048662 negative regulation of smooth muscle cell proliferation 5.365667e-7
GO:0032501 multicellular organismal process 6.356580e-7
GO:0009750 response to fructose stimulus 6.488931e-7
GO:0008217 regulation of blood pressure 6.666095e-7
GO:0009743 response to carbohydrate stimulus 6.667296e-7
GO:0000238 zygotene 7.083831e-7
GO:0003051 angiotensin-mediated drinking behavior 7.116906e-7
GO:0006732 coenzyme metabolic process 1.114015e-6
GO:0002684 positive regulation of immune system process 1.136770e-6
GO:0010866 regulation of triglyceride biosynthetic process 1.142974e-6
GO:0001878 response to yeast 1.151058e-6
GO:0009725 response to hormone stimulus 1.180907e-6
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.237998e-6
GO:0009306 protein secretion 1.290169e-6
GO:0008015 blood circulation 1.304911e-6
GO:0030010 establishment of cell polarity 1.311768e-6
GO:0010043 response to zinc ion 1.387097e-6
GO:0003018 vascular process in circulatory system 1.552956e-6
GO:0002700 regulation of production of molecular mediator of immune response 1.565754e-6
GO:0047497 mitochondrion transport along microtubule 1.777160e-6
GO:0031960 response to corticosteroid stimulus 1.779812e-6
GO:0017144 drug metabolic process 1.860260e-6
GO:0045807 positive regulation of endocytosis 1.869132e-6
GO:0048588 developmental cell growth 1.950714e-6
GO:0002819 regulation of adaptive immune response 2.143558e-6
GO:2000110 negative regulation of macrophage apoptosis 2.156663e-6
GO:0007154 cell communication 2.253823e-6
GO:0007166 cell surface receptor linked signaling pathway 2.299613e-6
GO:0001775 cell activation 2.401246e-6
GO:0055091 phospholipid homeostasis 2.403282e-6
GO:0033189 response to vitamin A 2.418837e-6
GO:0002250 adaptive immune response 3.548780e-6
GO:0051900 regulation of mitochondrial depolarization 3.667190e-6
GO:0006950 response to stress 3.841913e-6
GO:0009719 response to endogenous stimulus 4.249450e-6
GO:0050865 regulation of cell activation 4.506207e-6
GO:0070189 kynurenine metabolic process 4.745595e-6
GO:0051716 cellular response to stimulus 5.135694e-6
GO:0051654 establishment of mitochondrion localization 5.221105e-6
GO:0032101 regulation of response to external stimulus 5.294641e-6
GO:0009117 nucleotide metabolic process 5.351000e-6
GO:0060326 cell chemotaxis 5.360052e-6
GO:0045416 positive regulation of interleukin-8 biosynthetic process 5.404610e-6
GO:0031347 regulation of defense response 5.697576e-6
GO:0010942 positive regulation of cell death 5.781512e-6
GO:0002694 regulation of leukocyte activation 5.888669e-6
GO:0007586 digestion 6.265432e-6
GO:0055086 nucleobase-containing small molecule metabolic process 6.487295e-6
GO:0019731 antibacterial humoral response 6.528894e-6
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 6.646852e-6
GO:0045321 leukocyte activation 6.692753e-6
GO:0035644 phosphoanandamide dephosphorylation 6.936976e-6
GO:2000107 negative regulation of leukocyte apoptosis 7.174212e-6
GO:0032844 regulation of homeostatic process 7.700974e-6
GO:0001990 regulation of systemic arterial blood pressure by hormone 7.964961e-6
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 8.546307e-6
GO:0071496 cellular response to external stimulus 9.675846e-6
GO:0042493 response to drug 9.709911e-6
GO:0050880 regulation of blood vessel size 9.957473e-6
GO:0043549 regulation of kinase activity 1.035934e-5
GO:0001867 complement activation, lectin pathway 1.071309e-5
GO:0035150 regulation of tube size 1.075992e-5
GO:0050764 regulation of phagocytosis 1.218635e-5
GO:0070542 response to fatty acid 1.244087e-5
GO:0048675 axon extension 1.306573e-5
GO:0002702 positive regulation of production of molecular mediator of immune response 1.308216e-5
GO:0009968 negative regulation of signal transduction 1.312102e-5
GO:0051649 establishment of localization in cell 1.331766e-5
GO:0065008 regulation of biological quality 1.432107e-5
GO:0031334 positive regulation of protein complex assembly 1.447977e-5
GO:0031000 response to caffeine 1.516525e-5
GO:0009074 aromatic amino acid family catabolic process 1.535592e-5
GO:0051338 regulation of transferase activity 1.602580e-5
GO:0051186 cofactor metabolic process 1.636413e-5
GO:0023052 signaling 1.666377e-5
GO:0042325 regulation of phosphorylation 1.679352e-5
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1.697151e-5
GO:0032722 positive regulation of chemokine production 1.737466e-5
GO:0051234 establishment of localization 1.739703e-5
GO:0006812 cation transport 1.843362e-5
GO:0009651 response to salt stress 1.945048e-5
GO:0014041 regulation of neuron maturation 1.977120e-5
GO:0034762 regulation of transmembrane transport 2.048181e-5
GO:0030001 metal ion transport 2.057152e-5
GO:0050900 leukocyte migration 2.179440e-5
GO:0061084 negative regulation of protein refolding 2.216602e-5
GO:0060555 induction of necroptosis by extracellular signals 2.233308e-5
GO:0055085 transmembrane transport 2.233492e-5
GO:0008366 axon ensheathment 2.304355e-5
GO:0014826 vein smooth muscle contraction 2.342616e-5
GO:0014829 vascular smooth muscle contraction 2.357034e-5
GO:0051103 DNA ligation involved in DNA repair 2.409634e-5
GO:0019228 regulation of action potential in neuron 2.462022e-5
GO:0032868 response to insulin stimulus 2.548859e-5
GO:0045333 cellular respiration 2.758884e-5
GO:0045576 mast cell activation 2.823638e-5
GO:0006970 response to osmotic stress 2.835340e-5
GO:0051249 regulation of lymphocyte activation 2.869809e-5
GO:0048305 immunoglobulin secretion 2.901853e-5
GO:0010821 regulation of mitochondrion organization 2.930210e-5
GO:0007229 integrin-mediated signaling pathway 2.979833e-5
GO:0002034 regulation of blood vessel size by renin-angiotensin 3.055992e-5
GO:0001932 regulation of protein phosphorylation 3.163310e-5
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 3.165330e-5
GO:0002149 hypochlorous acid biosynthetic process 3.249904e-5
GO:0032273 positive regulation of protein polymerization 3.249910e-5
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 3.283841e-5
GO:0002637 regulation of immunoglobulin production 3.334686e-5
GO:0071594 thymocyte aggregation 3.492856e-5
GO:0043434 response to peptide hormone stimulus 3.531233e-5
GO:0051179 localization 3.685465e-5
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway 3.851599e-5
GO:0042552 myelination 3.860422e-5
GO:0000902 cell morphogenesis 3.937973e-5
GO:0030890 positive regulation of B cell proliferation 4.060395e-5
GO:0072376 protein activation cascade 4.115313e-5
GO:0051646 mitochondrion localization 4.150065e-5
GO:0050729 positive regulation of inflammatory response 4.383162e-5
GO:0070374 positive regulation of ERK1 and ERK2 cascade 4.764963e-5
GO:0006810 transport 4.914329e-5
GO:0001934 positive regulation of protein phosphorylation 5.035432e-5
GO:0022010 central nervous system myelination 5.117456e-5
GO:0019363 pyridine nucleotide biosynthetic process 5.155740e-5
GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport 5.234759e-5
GO:0070887 cellular response to chemical stimulus 5.251892e-5
GO:0009636 response to toxin 5.309484e-5
GO:0006207 'de novo' pyrimidine base biosynthetic process 5.386736e-5
GO:0071375 cellular response to peptide hormone stimulus 5.398696e-5
GO:0032675 regulation of interleukin-6 production 5.608320e-5
GO:0032765 positive regulation of mast cell cytokine production 5.734913e-5
GO:0002431 Fc receptor mediated stimulatory signaling pathway 5.734913e-5
GO:0002444 myeloid leukocyte mediated immunity 5.794552e-5
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 5.873007e-5
GO:0034220 ion transmembrane transport 6.038458e-5
GO:0001817 regulation of cytokine production 6.065552e-5
GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 6.142016e-5
GO:0070430 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 6.142016e-5
GO:0032707 negative regulation of interleukin-23 production 6.142016e-5
GO:0045362 positive regulation of interleukin-1 biosynthetic process 6.142016e-5
GO:0043388 positive regulation of DNA binding 6.162646e-5
GO:0006811 ion transport 6.272693e-5
GO:0043068 positive regulation of programmed cell death 6.286647e-5
GO:0042127 regulation of cell proliferation 6.325306e-5
GO:0051531 NFAT protein import into nucleus 6.426921e-5
GO:0010940 positive regulation of necrotic cell death 6.426921e-5
GO:0006956 complement activation 6.564535e-5
GO:0035458 cellular response to interferon-beta 6.749313e-5
GO:0010648 negative regulation of cell communication 6.971907e-5
GO:0046684 response to pyrethroid 7.106934e-5
GO:0006586 indolalkylamine metabolic process 7.135091e-5
GO:0007165 signal transduction 7.347112e-5
GO:0043550 regulation of lipid kinase activity 7.477513e-5
GO:0048519 negative regulation of biological process 7.555838e-5
GO:0009125 nucleoside monophosphate catabolic process 7.642182e-5
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7.756863e-5
GO:0050877 neurological system process 8.196051e-5
GO:0050830 defense response to Gram-positive bacterium 8.303324e-5
GO:0030002 cellular anion homeostasis 8.417823e-5
GO:0050766 positive regulation of phagocytosis 8.537568e-5
GO:0023051 regulation of signaling 8.750262e-5
GO:0033273 response to vitamin 8.843356e-5
GO:0014074 response to purine-containing compound 8.957425e-5
GO:0002761 regulation of myeloid leukocyte differentiation 9.017208e-5
GO:0002381 immunoglobulin production involved in immunoglobulin mediated immune response 9.193129e-5
GO:0055081 anion homeostasis 9.287188e-5
GO:0048246 macrophage chemotaxis 9.298536e-5
GO:0033152 immunoglobulin V(D)J recombination 9.339413e-5
GO:0006631 fatty acid metabolic process 9.541007e-5
GO:0023057 negative regulation of signaling 9.597829e-5
GO:0010623 developmental programmed cell death 9.642660e-5
GO:0009620 response to fungus 9.676352e-5
GO:0014012 peripheral nervous system axon regeneration 9.895544e-5
GO:0046092 deoxycytidine metabolic process 9.942093e-5
GO:0043065 positive regulation of apoptosis 9.993189e-5
GO:0007026 negative regulation of microtubule depolymerization 1.002770e-4
GO:0006266 DNA ligation 1.032800e-4
GO:0043558 regulation of translational initiation in response to stress 1.038847e-4
GO:0032989 cellular component morphogenesis 1.043380e-4
GO:0019220 regulation of phosphate metabolic process 1.076932e-4
GO:0070265 necrotic cell death 1.109463e-4
GO:0042311 vasodilation 1.121815e-4
GO:0070229 negative regulation of lymphocyte apoptosis 1.134963e-4
GO:0031114 regulation of microtubule depolymerization 1.153771e-4
GO:0048484 enteric nervous system development 1.157280e-4
GO:0032870 cellular response to hormone stimulus 1.174609e-4
GO:0042360 vitamin E metabolic process 1.188471e-4
GO:0002508 central tolerance induction 1.188471e-4
GO:0002897 positive regulation of central B cell tolerance induction 1.188471e-4
GO:0034765 regulation of ion transmembrane transport 1.222168e-4
GO:0009746 response to hexose stimulus 1.223574e-4
GO:0009612 response to mechanical stimulus 1.230084e-4
GO:0050863 regulation of T cell activation 1.241290e-4
GO:0002697 regulation of immune effector process 1.301271e-4
GO:0002455 humoral immune response mediated by circulating immunoglobulin 1.325482e-4
GO:0070432 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1.336809e-4
GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1.336809e-4
GO:0060044 negative regulation of cardiac muscle cell proliferation 1.340726e-4
GO:0050832 defense response to fungus 1.340726e-4
GO:0046889 positive regulation of lipid biosynthetic process 1.341827e-4
GO:0032869 cellular response to insulin stimulus 1.459541e-4
GO:0007631 feeding behavior 1.462523e-4
GO:0032387 negative regulation of intracellular transport 1.465902e-4
GO:0048013 ephrin receptor signaling pathway 1.520130e-4
GO:0048583 regulation of response to stimulus 1.569361e-4
GO:0046112 nucleobase biosynthetic process 1.572983e-4
GO:0016074 snoRNA metabolic process 1.576973e-4
GO:0031223 auditory behavior 1.594261e-4
GO:2000036 regulation of stem cell maintenance 1.621833e-4
GO:0050663 cytokine secretion 1.621833e-4
GO:0002446 neutrophil mediated immunity 1.621833e-4
GO:0010716 negative regulation of extracellular matrix disassembly 1.625446e-4
GO:0031111 negative regulation of microtubule polymerization or depolymerization 1.653240e-4
GO:0043269 regulation of ion transport 1.655202e-4
GO:0046907 intracellular transport 1.701366e-4
GO:0032661 regulation of interleukin-18 production 1.731806e-4
GO:0030643 cellular phosphate ion homeostasis 1.735877e-4
GO:0048518 positive regulation of biological process 1.761912e-4
GO:0043543 protein acylation 1.776067e-4
GO:0090199 regulation of release of cytochrome c from mitochondria 1.800879e-4
GO:0007163 establishment or maintenance of cell polarity 1.819318e-4
GO:0051641 cellular localization 1.841857e-4
GO:0015837 amine transport 1.859921e-4
GO:0048523 negative regulation of cellular process 1.870142e-4
GO:0002274 myeloid leukocyte activation 1.873122e-4
GO:0034284 response to monosaccharide stimulus 1.888068e-4
GO:0048790 maintenance of presynaptic active zone structure 1.901250e-4
GO:0001818 negative regulation of cytokine production 1.932593e-4
GO:0090066 regulation of anatomical structure size 1.949855e-4
GO:0070372 regulation of ERK1 and ERK2 cascade 2.066530e-4
GO:0046813 virion attachment, binding of host cell surface receptor 2.118017e-4
GO:2000309 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production 2.118017e-4
GO:0002635 negative regulation of germinal center formation 2.118017e-4
GO:0072384 organelle transport along microtubule 2.125983e-4
GO:0050866 negative regulation of cell activation 2.135294e-4
GO:0044419 interspecies interaction between organisms 2.165869e-4
GO:0007010 cytoskeleton organization 2.173057e-4
GO:0048660 regulation of smooth muscle cell proliferation 2.189689e-4
GO:0003254 regulation of membrane depolarization 2.210363e-4
GO:0000186 activation of MAPKK activity 2.252834e-4
GO:0045834 positive regulation of lipid metabolic process 2.292206e-4
GO:0010646 regulation of cell communication 2.346269e-4
GO:0045346 regulation of MHC class II biosynthetic process 2.362429e-4
GO:0046627 negative regulation of insulin receptor signaling pathway 2.367726e-4
GO:0006766 vitamin metabolic process 2.381019e-4
GO:0032185 septin cytoskeleton organization 2.451169e-4
GO:2000189 positive regulation of cholesterol homeostasis 2.451169e-4
GO:0045414 regulation of interleukin-8 biosynthetic process 2.499380e-4
GO:0050801 ion homeostasis 2.506968e-4
GO:0032787 monocarboxylic acid metabolic process 2.510390e-4
GO:0032944 regulation of mononuclear cell proliferation 2.531321e-4
GO:0002764 immune response-regulating signaling pathway 2.577034e-4
GO:0002606 positive regulation of dendritic cell antigen processing and presentation 2.598714e-4
GO:0031650 regulation of heat generation 2.605781e-4
GO:0051246 regulation of protein metabolic process 2.619349e-4
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 2.639037e-4
GO:0002695 negative regulation of leukocyte activation 2.641729e-4
GO:0048856 anatomical structure development 2.702813e-4
GO:0030574 collagen catabolic process 2.711706e-4
GO:0009072 aromatic amino acid family metabolic process 2.711706e-4
GO:0030162 regulation of proteolysis 2.771797e-4
GO:0019216 regulation of lipid metabolic process 2.790381e-4
GO:0055024 regulation of cardiac muscle tissue development 2.812276e-4
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 2.812865e-4
GO:0050670 regulation of lymphocyte proliferation 2.896921e-4
GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction 2.926088e-4
GO:0031113 regulation of microtubule polymerization 2.942378e-4
GO:0019730 antimicrobial humoral response 3.043856e-4
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 3.084026e-4
GO:0030888 regulation of B cell proliferation 3.106324e-4
GO:0042327 positive regulation of phosphorylation 3.175843e-4
GO:0051851 modification by host of symbiont morphology or physiology 3.178515e-4
GO:0034725 DNA replication-dependent nucleosome disassembly 3.243765e-4
GO:0034136 negative regulation of toll-like receptor 2 signaling pathway 3.243765e-4
GO:2000363 positive regulation of prostaglandin-E synthase activity 3.243765e-4
GO:0071608 macrophage inflammatory protein-1 alpha production 3.243765e-4
GO:0006965 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 3.243765e-4
GO:0032498 detection of muramyl dipeptide 3.243765e-4
GO:0032701 negative regulation of interleukin-18 production 3.243765e-4
GO:0014056 regulation of acetylcholine secretion 3.301628e-4
GO:0016197 endosome transport 3.474699e-4
GO:0002720 positive regulation of cytokine production involved in immune response 3.484398e-4
GO:0002673 regulation of acute inflammatory response 3.562293e-4
GO:0010939 regulation of necrotic cell death 3.570694e-4
GO:0007638 mechanosensory behavior 3.678935e-4
GO:0008286 insulin receptor signaling pathway 3.745054e-4
GO:0032570 response to progesterone stimulus 3.747638e-4
GO:0000072 M phase specific microtubule process 3.749315e-4
GO:0002903 negative regulation of B cell apoptosis 3.791296e-4
GO:0002757 immune response-activating signal transduction 3.834525e-4
GO:0031112 positive regulation of microtubule polymerization or depolymerization 3.879503e-4
GO:0043966 histone H3 acetylation 3.905328e-4
GO:0006576 cellular biogenic amine metabolic process 3.906325e-4
GO:0090193 positive regulation of glomerulus development 3.998457e-4
GO:0070663 regulation of leukocyte proliferation 4.025315e-4
GO:0050790 regulation of catalytic activity 4.032979e-4
GO:0032147 activation of protein kinase activity 4.111986e-4
GO:0032763 regulation of mast cell cytokine production 4.114051e-4
GO:0035023 regulation of Rho protein signal transduction 4.134437e-4
GO:0032502 developmental process 4.231663e-4
GO:0072274 metanephric glomerular basement membrane development 4.272611e-4
GO:0072249 metanephric glomerular visceral epithelial cell development 4.272611e-4
GO:0061015 snRNA import into nucleus 4.272611e-4
GO:0048677 axon extension involved in regeneration 4.272611e-4
GO:0065009 regulation of molecular function 4.291864e-4
GO:0051023 regulation of immunoglobulin secretion 4.362927e-4
GO:2000736 regulation of stem cell differentiation 4.462827e-4
GO:0006935 chemotaxis 4.467262e-4
GO:0070278 extracellular matrix constituent secretion 4.535020e-4
GO:0002693 positive regulation of cellular extravasation 4.535020e-4
GO:0010260 organ senescence 4.535020e-4
GO:0045348 positive regulation of MHC class II biosynthetic process 4.567382e-4
GO:0010970 microtubule-based transport 4.576675e-4
GO:0071593 lymphocyte aggregation 4.600922e-4
GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide 4.600922e-4
GO:0016573 histone acetylation 4.613453e-4
GO:0007167 enzyme linked receptor protein signaling pathway 4.641455e-4
GO:0002426 immunoglobulin production in mucosal tissue 4.641676e-4
GO:0051702 interaction with symbiont 4.653191e-4
GO:0033151 V(D)J recombination 4.668316e-4
GO:0031399 regulation of protein modification process 4.678621e-4
GO:0006775 fat-soluble vitamin metabolic process 4.736557e-4
GO:0002064 epithelial cell development 4.757366e-4
GO:0009214 cyclic nucleotide catabolic process 4.808586e-4
GO:0006633 fatty acid biosynthetic process 4.971367e-4
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 4.987189e-4
GO:0043900 regulation of multi-organism process 5.025496e-4
GO:0060043 regulation of cardiac muscle cell proliferation 5.034173e-4
GO:0070602 regulation of centromeric sister chromatid cohesion 5.069081e-4
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 5.069081e-4
GO:0061181 regulation of chondrocyte development 5.120381e-4
GO:0002906 negative regulation of mature B cell apoptosis 5.151708e-4
GO:0010638 positive regulation of organelle organization 5.167933e-4
GO:0030098 lymphocyte differentiation 5.177208e-4
GO:0045368 positive regulation of interleukin-13 biosynthetic process 5.200556e-4
GO:0050868 negative regulation of T cell activation 5.232811e-4
GO:0046125 pyrimidine deoxyribonucleoside metabolic process 5.275500e-4
GO:0042297 vocal learning 5.275500e-4
GO:0007034 vacuolar transport 5.391461e-4
GO:0014823 response to activity 5.465192e-4
GO:0042330 taxis 5.477664e-4
GO:0002889 regulation of immunoglobulin mediated immune response 5.600191e-4
GO:0071260 cellular response to mechanical stimulus 5.716492e-4
GO:0042756 drinking behavior 5.756655e-4
GO:0045087 innate immune response 5.783563e-4
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity 5.826136e-4
GO:0044270 cellular nitrogen compound catabolic process 5.841926e-4
GO:0002828 regulation of type 2 immune response 5.851959e-4
GO:0006882 cellular zinc ion homeostasis 5.902700e-4
GO:0002521 leukocyte differentiation 5.952280e-4
GO:0055021 regulation of cardiac muscle tissue growth 6.076461e-4
GO:0045670 regulation of osteoclast differentiation 6.078556e-4
GO:0007186 G-protein coupled receptor protein signaling pathway 6.106816e-4
GO:0031103 axon regeneration 6.277145e-4
GO:0015813 L-glutamate transport 6.297484e-4
GO:0030100 regulation of endocytosis 6.383555e-4
GO:0051250 negative regulation of lymphocyte activation 6.405173e-4
GO:0007032 endosome organization 6.564165e-4
GO:0051873 killing by host of symbiont cells 6.564303e-4
GO:0006739 NADP metabolic process 6.566426e-4
GO:0045859 regulation of protein kinase activity 6.580029e-4
GO:0032462 regulation of protein homooligomerization 6.636560e-4
GO:0046942 carboxylic acid transport 6.664329e-4
GO:0009628 response to abiotic stimulus 6.712465e-4
GO:0051101 regulation of DNA binding 6.729488e-4
GO:0010661 positive regulation of muscle cell apoptosis 6.741529e-4
GO:0007141 male meiosis I 6.741529e-4
GO:0006098 pentose-phosphate shunt 6.829849e-4
GO:0042119 neutrophil activation 6.940095e-4
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 7.075984e-4
GO:0034114 regulation of heterotypic cell-cell adhesion 7.075984e-4
GO:0006824 cobalt ion transport 7.075984e-4
GO:0032202 telomere assembly 7.094467e-4
GO:0046890 regulation of lipid biosynthetic process 7.183914e-4
GO:0042384 cilium assembly 7.187940e-4
GO:0031349 positive regulation of defense response 7.337543e-4
GO:0016049 cell growth 7.372624e-4
GO:0018393 internal peptidyl-lysine acetylation 7.385238e-4
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 7.517550e-4
GO:0032755 positive regulation of interleukin-6 production 7.525436e-4
GO:0010040 response to iron(II) ion 7.541380e-4
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 7.541380e-4
GO:0048630 skeletal muscle tissue growth 7.541380e-4
GO:0046649 lymphocyte activation 7.721106e-4
GO:0033993 response to lipid 7.840914e-4
GO:0070309 lens fiber cell morphogenesis 7.888174e-4
GO:0070970 interleukin-2 secretion 7.927149e-4
GO:0070236 negative regulation of activation-induced cell death of T cells 7.927149e-4
GO:0002366 leukocyte activation involved in immune response 8.101232e-4
GO:0043171 peptide catabolic process 8.202004e-4
GO:0032102 negative regulation of response to external stimulus 8.266734e-4
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 8.276361e-4
GO:0052548 regulation of endopeptidase activity 8.322279e-4
GO:0002439 chronic inflammatory response to antigenic stimulus 8.356986e-4
GO:0046058 cAMP metabolic process 8.392692e-4
GO:0071214 cellular response to abiotic stimulus 8.483705e-4
GO:0071705 nitrogen compound transport 8.493574e-4
GO:0035249 synaptic transmission, glutamatergic 8.515657e-4
GO:0044243 multicellular organismal catabolic process 8.521945e-4
GO:0040008 regulation of growth 8.692539e-4
GO:0034121 regulation of toll-like receptor signaling pathway 8.746037e-4
GO:0034143 regulation of toll-like receptor 4 signaling pathway 9.079995e-4
GO:0018394 peptidyl-lysine acetylation 9.125372e-4
GO:0015849 organic acid transport 9.154122e-4
GO:0006288 base-excision repair, DNA ligation 9.180201e-4
GO:0048678 response to axon injury 9.582669e-4
GO:0070838 divalent metal ion transport 9.649390e-4
GO:0060452 positive regulation of cardiac muscle contraction 9.721387e-4
GO:2000188 regulation of cholesterol homeostasis 9.771650e-4
GO:0051239 regulation of multicellular organismal process 9.821828e-4
GO:0031620 regulation of fever generation 9.865545e-4
GO:0050808 synapse organization 9.895893e-4
GO:0022408 negative regulation of cell-cell adhesion 9.936514e-4
GO:0032459 regulation of protein oligomerization 1.008430e-3
GO:0051128 regulation of cellular component organization 1.009326e-3
GO:0060341 regulation of cellular localization 1.011169e-3
GO:0000041 transition metal ion transport 1.020285e-3
GO:0050864 regulation of B cell activation 1.046674e-3
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 1.076896e-3
GO:0044205 'de novo' UMP biosynthetic process 1.079084e-3
GO:0010536 positive regulation of activation of Janus kinase activity 1.079084e-3
GO:0050728 negative regulation of inflammatory response 1.082835e-3
GO:2000425 regulation of apoptotic cell clearance 1.088467e-3
GO:0050771 negative regulation of axonogenesis 1.095731e-3
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly 1.098514e-3
GO:0001889 liver development 1.109802e-3
GO:0002676 regulation of chronic inflammatory response 1.121128e-3
GO:0033674 positive regulation of kinase activity 1.125652e-3
GO:0006650 glycerophospholipid metabolic process 1.140130e-3