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Novel motif:81

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name:motif81_NGCAGAA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0032501 multicellular organismal process 2.309648e-35
GO:0003008 system process 5.682974e-29
GO:0050896 response to stimulus 7.997309e-26
GO:0048731 system development 3.910117e-24
GO:0048856 anatomical structure development 2.210390e-23
GO:0007275 multicellular organismal development 1.416824e-21
GO:0007154 cell communication 2.137722e-21
GO:0032502 developmental process 5.603505e-21
GO:0003012 muscle system process 4.681002e-20
GO:0048513 organ development 6.756789e-20
GO:0023052 signaling 1.737550e-18
GO:0006950 response to stress 1.820951e-18
GO:0065007 biological regulation 9.178202e-18
GO:0051716 cellular response to stimulus 2.745065e-17
GO:0030730 sequestering of triglyceride 5.533141e-17
GO:0009888 tissue development 1.027961e-16
GO:0048583 regulation of response to stimulus 2.936310e-16
GO:0006936 muscle contraction 3.263141e-16
GO:0007165 signal transduction 1.149214e-15
GO:0032101 regulation of response to external stimulus 3.446555e-15
GO:0050789 regulation of biological process 6.276252e-15
GO:0031424 keratinization 8.253442e-15
GO:0034116 positive regulation of heterotypic cell-cell adhesion 2.708290e-14
GO:0080134 regulation of response to stress 4.619301e-14
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 5.404475e-14
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 9.154120e-14
GO:0051043 regulation of membrane protein ectodomain proteolysis 1.225906e-13
GO:0010466 negative regulation of peptidase activity 1.705826e-13
GO:0009611 response to wounding 2.531144e-13
GO:0065008 regulation of biological quality 2.772024e-13
GO:0002682 regulation of immune system process 2.957823e-13
GO:0002376 immune system process 3.363715e-13
GO:0043086 negative regulation of catalytic activity 3.568101e-13
GO:0007166 cell surface receptor linked signaling pathway 9.103405e-13
GO:0052547 regulation of peptidase activity 9.463359e-13
GO:0009266 response to temperature stimulus 1.045810e-12
GO:0031099 regeneration 1.068680e-12
GO:0042221 response to chemical stimulus 1.156611e-12
GO:0070164 negative regulation of adiponectin secretion 2.398281e-12
GO:0060355 positive regulation of cell adhesion molecule production 2.398281e-12
GO:0035505 positive regulation of myosin light chain kinase activity 2.398281e-12
GO:0006952 defense response 2.853220e-12
GO:0007267 cell-cell signaling 3.074372e-12
GO:0019915 lipid storage 3.658579e-12
GO:0030855 epithelial cell differentiation 3.881178e-12
GO:0051346 negative regulation of hydrolase activity 4.495485e-12
GO:0009408 response to heat 5.727763e-12
GO:0050995 negative regulation of lipid catabolic process 6.494326e-12
GO:0050877 neurological system process 6.781789e-12
GO:0070163 regulation of adiponectin secretion 8.118651e-12
GO:0050727 regulation of inflammatory response 8.301971e-12
GO:0031347 regulation of defense response 8.404318e-12
GO:0014866 skeletal myofibril assembly 8.467480e-12
GO:0030029 actin filament-based process 9.861392e-12
GO:0007155 cell adhesion 1.267266e-11
GO:0048869 cellular developmental process 1.299117e-11
GO:0006928 cellular component movement 1.546580e-11
GO:0030154 cell differentiation 1.626616e-11
GO:0051234 establishment of localization 1.918611e-11
GO:0009725 response to hormone stimulus 2.236132e-11
GO:0051179 localization 2.697097e-11
GO:0010829 negative regulation of glucose transport 3.867040e-11
GO:0009913 epidermal cell differentiation 4.859974e-11
GO:0044060 regulation of endocrine process 5.149020e-11
GO:0002684 positive regulation of immune system process 6.027171e-11
GO:0048545 response to steroid hormone stimulus 7.839838e-11
GO:0050794 regulation of cellular process 9.023188e-11
GO:0042060 wound healing 1.029920e-10
GO:0043500 muscle adaptation 1.210753e-10
GO:0051240 positive regulation of multicellular organismal process 1.219175e-10
GO:0040007 growth 1.323885e-10
GO:0048584 positive regulation of response to stimulus 1.351991e-10
GO:0007610 behavior 1.663907e-10
GO:0031915 positive regulation of synaptic plasticity 1.688393e-10
GO:0007015 actin filament organization 1.693916e-10
GO:0030216 keratinocyte differentiation 2.570333e-10
GO:0001660 fever generation 2.778394e-10
GO:0030049 muscle filament sliding 2.853470e-10
GO:0030048 actin filament-based movement 3.319338e-10
GO:0048585 negative regulation of response to stimulus 3.559627e-10
GO:0051480 cytosolic calcium ion homeostasis 3.607388e-10
GO:0070252 actin-mediated cell contraction 5.041062e-10
GO:0045785 positive regulation of cell adhesion 5.243123e-10
GO:0001775 cell activation 5.651952e-10
GO:0009605 response to external stimulus 5.814760e-10
GO:0044092 negative regulation of molecular function 6.401272e-10
GO:0008544 epidermis development 7.008886e-10
GO:0048747 muscle fiber development 7.284274e-10
GO:0048739 cardiac muscle fiber development 7.574204e-10
GO:0050778 positive regulation of immune response 8.136744e-10
GO:0042993 positive regulation of transcription factor import into nucleus 8.351982e-10
GO:0042990 regulation of transcription factor import into nucleus 8.755144e-10
GO:0031960 response to corticosteroid stimulus 9.176930e-10
GO:0002439 chronic inflammatory response to antigenic stimulus 9.866799e-10
GO:0052548 regulation of endopeptidase activity 1.007073e-9
GO:0009617 response to bacterium 1.017222e-9
GO:0034605 cellular response to heat 1.088883e-9
GO:0030036 actin cytoskeleton organization 1.257394e-9
GO:0007163 establishment or maintenance of cell polarity 1.267876e-9
GO:0006810 transport 1.282581e-9
GO:0010951 negative regulation of endopeptidase activity 1.421785e-9
GO:0045408 regulation of interleukin-6 biosynthetic process 1.617573e-9
GO:0050776 regulation of immune response 1.860141e-9
GO:0006359 regulation of transcription from RNA polymerase III promoter 1.885191e-9
GO:0065009 regulation of molecular function 1.968771e-9
GO:0002673 regulation of acute inflammatory response 2.032139e-9
GO:0048518 positive regulation of biological process 2.044923e-9
GO:0035690 cellular response to drug 2.305230e-9
GO:0051384 response to glucocorticoid stimulus 2.382133e-9
GO:0060558 regulation of calcidiol 1-monooxygenase activity 2.456836e-9
GO:0007399 nervous system development 2.793614e-9
GO:0008015 blood circulation 3.500008e-9
GO:0006955 immune response 3.501810e-9
GO:0003013 circulatory system process 3.753991e-9
GO:0007631 feeding behavior 4.079187e-9
GO:0051293 establishment of spindle localization 4.186813e-9
GO:0014050 negative regulation of glutamate secretion 4.648768e-9
GO:0007517 muscle organ development 4.840073e-9
GO:0030241 skeletal muscle myosin thick filament assembly 5.135920e-9
GO:0010035 response to inorganic substance 5.171874e-9
GO:0002576 platelet degranulation 5.633973e-9
GO:0006811 ion transport 6.839613e-9
GO:0010646 regulation of cell communication 6.996575e-9
GO:0006939 smooth muscle contraction 8.912663e-9
GO:0032846 positive regulation of homeostatic process 9.966253e-9
GO:0007204 elevation of cytosolic calcium ion concentration 1.146968e-8
GO:0031110 regulation of microtubule polymerization or depolymerization 1.158636e-8
GO:0008037 cell recognition 1.182030e-8
GO:0070887 cellular response to chemical stimulus 1.212722e-8
GO:0006874 cellular calcium ion homeostasis 1.348563e-8
GO:0030593 neutrophil chemotaxis 1.355451e-8
GO:0032940 secretion by cell 1.381496e-8
GO:0032879 regulation of localization 1.395158e-8
GO:0045410 positive regulation of interleukin-6 biosynthetic process 1.406074e-8
GO:0042346 positive regulation of NF-kappaB import into nucleus 1.626956e-8
GO:0055074 calcium ion homeostasis 1.723251e-8
GO:0072503 cellular divalent inorganic cation homeostasis 1.737604e-8
GO:0012501 programmed cell death 1.879103e-8
GO:0006915 apoptosis 1.931555e-8
GO:0001659 temperature homeostasis 1.955823e-8
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1.986017e-8
GO:0043627 response to estrogen stimulus 2.178075e-8
GO:0030239 myofibril assembly 2.194731e-8
GO:0032103 positive regulation of response to external stimulus 2.224485e-8
GO:0032757 positive regulation of interleukin-8 production 2.452870e-8
GO:0051606 detection of stimulus 2.588247e-8
GO:0032892 positive regulation of organic acid transport 2.896755e-8
GO:0033129 positive regulation of histone phosphorylation 2.991101e-8
GO:0015698 inorganic anion transport 3.011401e-8
GO:0030010 establishment of cell polarity 3.100482e-8
GO:0043278 response to morphine 3.156225e-8
GO:0071310 cellular response to organic substance 4.072211e-8
GO:0007548 sex differentiation 4.084025e-8
GO:0055002 striated muscle cell development 4.286016e-8
GO:0055001 muscle cell development 4.510409e-8
GO:0031652 positive regulation of heat generation 4.548340e-8
GO:0051592 response to calcium ion 5.424750e-8
GO:0031622 positive regulation of fever generation 5.589410e-8
GO:0032886 regulation of microtubule-based process 5.790499e-8
GO:0009653 anatomical structure morphogenesis 5.910754e-8
GO:0002544 chronic inflammatory response 6.510857e-8
GO:0050729 positive regulation of inflammatory response 6.667646e-8
GO:0007268 synaptic transmission 6.672475e-8
GO:0009719 response to endogenous stimulus 6.765443e-8
GO:0070507 regulation of microtubule cytoskeleton organization 7.294203e-8
GO:0051707 response to other organism 7.512055e-8
GO:0019805 quinolinate biosynthetic process 7.596705e-8
GO:0009987 cellular process 7.639517e-8
GO:0072507 divalent inorganic cation homeostasis 8.292204e-8
GO:0010033 response to organic substance 8.330416e-8
GO:0034762 regulation of transmembrane transport 8.993245e-8
GO:0007417 central nervous system development 9.408599e-8
GO:0051094 positive regulation of developmental process 9.673896e-8
GO:0048871 multicellular organismal homeostasis 1.001709e-7
GO:0042745 circadian sleep/wake cycle 1.006346e-7
GO:0040001 establishment of mitotic spindle localization 1.017893e-7
GO:0016049 cell growth 1.066976e-7
GO:0016265 death 1.223980e-7
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1.234511e-7
GO:0048251 elastic fiber assembly 1.256637e-7
GO:0007156 homophilic cell adhesion 1.279810e-7
GO:0007611 learning or memory 1.360937e-7
GO:0030505 inorganic diphosphate transport 1.426771e-7
GO:0051239 regulation of multicellular organismal process 1.430488e-7
GO:0023051 regulation of signaling 1.511221e-7
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 1.538613e-7
GO:0000132 establishment of mitotic spindle orientation 1.544565e-7
GO:0051050 positive regulation of transport 1.624780e-7
GO:0050870 positive regulation of T cell activation 1.661158e-7
GO:0090287 regulation of cellular response to growth factor stimulus 1.794592e-7
GO:0008219 cell death 1.864674e-7
GO:0048771 tissue remodeling 1.910151e-7
GO:0090316 positive regulation of intracellular protein transport 1.938158e-7
GO:0033157 regulation of intracellular protein transport 1.972794e-7
GO:0048522 positive regulation of cellular process 2.427574e-7
GO:0042246 tissue regeneration 2.452752e-7
GO:0050867 positive regulation of cell activation 2.479077e-7
GO:0002675 positive regulation of acute inflammatory response 2.553056e-7
GO:0031349 positive regulation of defense response 2.623160e-7
GO:0043501 skeletal muscle adaptation 2.669182e-7
GO:0051235 maintenance of location 2.814033e-7
GO:0040011 locomotion 3.111807e-7
GO:0006821 chloride transport 3.238129e-7
GO:0051251 positive regulation of lymphocyte activation 3.358497e-7
GO:0061061 muscle structure development 3.415924e-7
GO:0042306 regulation of protein import into nucleus 3.443312e-7
GO:0051298 centrosome duplication 3.480792e-7
GO:0044057 regulation of system process 3.666464e-7
GO:0010927 cellular component assembly involved in morphogenesis 3.703246e-7
GO:0014048 regulation of glutamate secretion 3.709489e-7
GO:0050890 cognition 3.790033e-7
GO:0035330 regulation of hippo signaling cascade 3.862439e-7
GO:0042592 homeostatic process 3.924763e-7
GO:0055065 metal ion homeostasis 3.951845e-7
GO:0071639 positive regulation of monocyte chemotactic protein-1 production 4.027107e-7
GO:0009991 response to extracellular stimulus 4.114456e-7
GO:0034114 regulation of heterotypic cell-cell adhesion 4.217019e-7
GO:0070587 regulation of cell-cell adhesion involved in gastrulation 4.217019e-7
GO:0007010 cytoskeleton organization 4.715407e-7
GO:0031032 actomyosin structure organization 4.738628e-7
GO:0006875 cellular metal ion homeostasis 5.048764e-7
GO:0032092 positive regulation of protein binding 5.117922e-7
GO:0048512 circadian behavior 5.363354e-7
GO:0022410 circadian sleep/wake cycle process 5.428861e-7
GO:0032989 cellular component morphogenesis 5.593913e-7
GO:0009607 response to biotic stimulus 5.913831e-7
GO:0030168 platelet activation 5.995631e-7
GO:0042307 positive regulation of protein import into nucleus 6.014452e-7
GO:0014805 smooth muscle adaptation 6.160144e-7
GO:0022008 neurogenesis 6.489937e-7
GO:0018149 peptide cross-linking 6.648326e-7
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 6.678829e-7
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 6.679157e-7
GO:0009968 negative regulation of signal transduction 6.936239e-7
GO:0031112 positive regulation of microtubule polymerization or depolymerization 6.975643e-7
GO:0033591 response to L-ascorbic acid 7.008074e-7
GO:0060429 epithelium development 7.268179e-7
GO:0007622 rhythmic behavior 7.360496e-7
GO:0045137 development of primary sexual characteristics 7.495270e-7
GO:0002697 regulation of immune effector process 7.860687e-7
GO:0085029 extracellular matrix assembly 7.918026e-7
GO:0051249 regulation of lymphocyte activation 7.941730e-7
GO:0055082 cellular chemical homeostasis 8.046805e-7
GO:0019226 transmission of nerve impulse 8.101562e-7
GO:0032388 positive regulation of intracellular transport 8.112166e-7
GO:0071495 cellular response to endogenous stimulus 8.306646e-7
GO:0045945 positive regulation of transcription from RNA polymerase III promoter 8.327215e-7
GO:0051336 regulation of hydrolase activity 8.923312e-7
GO:0071402 cellular response to lipoprotein particle stimulus 8.987074e-7
GO:0006941 striated muscle contraction 8.992370e-7
GO:0046627 negative regulation of insulin receptor signaling pathway 9.344944e-7
GO:0045214 sarcomere organization 9.853156e-7
GO:2000193 positive regulation of fatty acid transport 9.854214e-7
GO:0050790 regulation of catalytic activity 1.006053e-6
GO:0042310 vasoconstriction 1.017733e-6
GO:0008038 neuron recognition 1.059411e-6
GO:0006873 cellular ion homeostasis 1.069913e-6
GO:0002237 response to molecule of bacterial origin 1.083629e-6
GO:0010332 response to gamma radiation 1.114872e-6
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 1.150862e-6
GO:0002696 positive regulation of leukocyte activation 1.207284e-6
GO:0050865 regulation of cell activation 1.226061e-6
GO:0046827 positive regulation of protein export from nucleus 1.240386e-6
GO:0046874 quinolinate metabolic process 1.262654e-6
GO:0019725 cellular homeostasis 1.278667e-6
GO:0021987 cerebral cortex development 1.302658e-6
GO:0034764 positive regulation of transmembrane transport 1.356091e-6
GO:0031109 microtubule polymerization or depolymerization 1.363913e-6
GO:0050863 regulation of T cell activation 1.400824e-6
GO:0030240 skeletal muscle thin filament assembly 1.404693e-6
GO:0045076 regulation of interleukin-2 biosynthetic process 1.417115e-6
GO:0050906 detection of stimulus involved in sensory perception 1.453669e-6
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1.524510e-6
GO:0030003 cellular cation homeostasis 1.527393e-6
GO:0071840 cellular component organization or biogenesis 1.557323e-6
GO:0051047 positive regulation of secretion 1.567347e-6
GO:0051704 multi-organism process 1.572319e-6
GO:0022409 positive regulation of cell-cell adhesion 1.584098e-6
GO:0010631 epithelial cell migration 1.594261e-6
GO:0033198 response to ATP 1.637541e-6
GO:0002708 positive regulation of lymphocyte mediated immunity 1.645955e-6
GO:0030595 leukocyte chemotaxis 1.741861e-6
GO:0033127 regulation of histone phosphorylation 1.862830e-6
GO:0002253 activation of immune response 1.864642e-6
GO:0032755 positive regulation of interleukin-6 production 1.895262e-6
GO:0010648 negative regulation of cell communication 1.953101e-6
GO:0030198 extracellular matrix organization 1.969721e-6
GO:0003018 vascular process in circulatory system 2.043115e-6
GO:0030182 neuron differentiation 2.232686e-6
GO:0010193 response to ozone 2.234571e-6
GO:0007186 G-protein coupled receptor protein signaling pathway 2.320903e-6
GO:0071404 cellular response to low-density lipoprotein particle stimulus 2.321505e-6
GO:0006935 chemotaxis 2.334031e-6
GO:0007613 memory 2.337036e-6
GO:0050801 ion homeostasis 2.356079e-6
GO:0002694 regulation of leukocyte activation 2.393308e-6
GO:0043503 skeletal muscle fiber adaptation 2.427914e-6
GO:0008406 gonad development 2.516816e-6
GO:0023057 negative regulation of signaling 2.525035e-6
GO:0051725 protein de-ADP-ribosylation 2.552800e-6
GO:0006968 cellular defense response 2.581631e-6
GO:0031667 response to nutrient levels 2.628556e-6
GO:0010470 regulation of gastrulation 2.701225e-6
GO:0048608 reproductive structure development 2.863943e-6
GO:0031113 regulation of microtubule polymerization 3.079708e-6
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 3.202834e-6
GO:0009628 response to abiotic stimulus 3.242734e-6
GO:0000302 response to reactive oxygen species 3.322124e-6
GO:0046903 secretion 3.336658e-6
GO:0051348 negative regulation of transferase activity 3.363803e-6
GO:0009409 response to cold 3.388637e-6
GO:0034516 response to vitamin B6 3.742811e-6
GO:0043420 anthranilate metabolic process 3.742811e-6
GO:0051649 establishment of localization in cell 3.893994e-6
GO:0042345 regulation of NF-kappaB import into nucleus 3.913242e-6
GO:0045765 regulation of angiogenesis 3.935520e-6
GO:0045086 positive regulation of interleukin-2 biosynthetic process 3.951041e-6
GO:0051049 regulation of transport 3.973527e-6
GO:0007612 learning 3.976693e-6
GO:0043526 neuroprotection 4.001899e-6
GO:0060401 cytosolic calcium ion transport 4.050573e-6
GO:0032308 positive regulation of prostaglandin secretion 4.243152e-6
GO:0051017 actin filament bundle assembly 4.305457e-6
GO:0051641 cellular localization 4.673824e-6
GO:0050994 regulation of lipid catabolic process 4.836438e-6
GO:0033673 negative regulation of kinase activity 4.892141e-6
GO:0045187 regulation of circadian sleep/wake cycle, sleep 4.923954e-6
GO:0007600 sensory perception 4.982258e-6
GO:0007584 response to nutrient 4.991236e-6
GO:0018874 benzoate metabolic process 5.173779e-6
GO:0040014 regulation of multicellular organism growth 5.445251e-6
GO:0007596 blood coagulation 5.519698e-6
GO:0048878 chemical homeostasis 5.565709e-6
GO:0006816 calcium ion transport 5.571714e-6
GO:0050795 regulation of behavior 5.668975e-6
GO:0032878 regulation of establishment or maintenance of cell polarity 6.178407e-6
GO:0007599 hemostasis 6.461408e-6
GO:0019442 tryptophan catabolic process to acetyl-CoA 6.643679e-6
GO:0016199 axon midline choice point recognition 6.986936e-6
GO:0045080 positive regulation of chemokine biosynthetic process 7.150959e-6
GO:0001573 ganglioside metabolic process 7.165332e-6
GO:0042035 regulation of cytokine biosynthetic process 7.222373e-6
GO:0007420 brain development 7.658281e-6
GO:0014706 striated muscle tissue development 7.830162e-6
GO:0046824 positive regulation of nucleocytoplasmic transport 7.929497e-6
GO:0016043 cellular component organization 8.064860e-6
GO:0071637 regulation of monocyte chemotactic protein-1 production 8.111499e-6
GO:0032677 regulation of interleukin-8 production 8.462212e-6
GO:0007016 cytoskeletal anchoring at plasma membrane 8.549624e-6
GO:0010574 regulation of vascular endothelial growth factor production 9.358072e-6
GO:0045073 regulation of chemokine biosynthetic process 1.015789e-5
GO:0042542 response to hydrogen peroxide 1.035795e-5
GO:0031668 cellular response to extracellular stimulus 1.064321e-5
GO:0031100 organ regeneration 1.080137e-5
GO:0032496 response to lipopolysaccharide 1.143146e-5
GO:0032386 regulation of intracellular transport 1.256263e-5
GO:0042063 gliogenesis 1.322891e-5
GO:0032770 positive regulation of monooxygenase activity 1.324185e-5
GO:0042742 defense response to bacterium 1.377570e-5
GO:0009593 detection of chemical stimulus 1.413249e-5
GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages 1.414395e-5
GO:0016198 axon choice point recognition 1.419910e-5
GO:0045409 negative regulation of interleukin-6 biosynthetic process 1.449741e-5
GO:0042753 positive regulation of circadian rhythm 1.458716e-5
GO:0000902 cell morphogenesis 1.549544e-5
GO:0010941 regulation of cell death 1.590955e-5
GO:0048699 generation of neurons 1.653909e-5
GO:0019216 regulation of lipid metabolic process 1.686836e-5
GO:0048520 positive regulation of behavior 1.691704e-5
GO:0007098 centrosome cycle 1.782385e-5
GO:0046785 microtubule polymerization 1.803528e-5
GO:0048631 regulation of skeletal muscle tissue growth 1.807371e-5
GO:0015671 oxygen transport 1.859781e-5
GO:0031929 TOR signaling cascade 1.886043e-5
GO:0002520 immune system development 1.910525e-5
GO:0006469 negative regulation of protein kinase activity 1.932693e-5
GO:0060452 positive regulation of cardiac muscle contraction 1.934262e-5
GO:0045216 cell-cell junction organization 1.944635e-5
GO:0046546 development of primary male sexual characteristics 1.944728e-5
GO:0046322 negative regulation of fatty acid oxidation 1.990534e-5
GO:0002687 positive regulation of leukocyte migration 2.019050e-5
GO:0007601 visual perception 2.061437e-5
GO:0034330 cell junction organization 2.116856e-5
GO:0007616 long-term memory 2.121621e-5
GO:0009966 regulation of signal transduction 2.146587e-5
GO:0055080 cation homeostasis 2.187399e-5
GO:0033523 histone H2B ubiquitination 2.252694e-5
GO:0031669 cellular response to nutrient levels 2.271792e-5
GO:0030193 regulation of blood coagulation 2.279198e-5
GO:0045807 positive regulation of endocytosis 2.390276e-5
GO:0002764 immune response-regulating signaling pathway 2.456335e-5
GO:0021543 pallium development 2.460562e-5
GO:0050953 sensory perception of light stimulus 2.463746e-5
GO:0046622 positive regulation of organ growth 2.536075e-5
GO:0031640 killing of cells of other organism 2.648444e-5
GO:0042036 negative regulation of cytokine biosynthetic process 2.648449e-5
GO:0008207 C21-steroid hormone metabolic process 2.648449e-5
GO:0061041 regulation of wound healing 2.761082e-5
GO:0043549 regulation of kinase activity 2.825549e-5
GO:0045104 intermediate filament cytoskeleton organization 2.865426e-5
GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity 2.896648e-5
GO:2000191 regulation of fatty acid transport 2.941440e-5
GO:0030162 regulation of proteolysis 2.976024e-5
GO:0040008 regulation of growth 3.083655e-5
GO:0035150 regulation of tube size 3.127249e-5
GO:0002706 regulation of lymphocyte mediated immunity 3.157785e-5
GO:0007567 parturition 3.248911e-5
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 3.273232e-5
GO:0009755 hormone-mediated signaling pathway 3.284640e-5
GO:0030155 regulation of cell adhesion 3.299732e-5
GO:0009267 cellular response to starvation 3.306909e-5
GO:0002437 inflammatory response to antigenic stimulus 3.382470e-5
GO:0045762 positive regulation of adenylate cyclase activity 3.489567e-5
GO:0043407 negative regulation of MAP kinase activity 3.505146e-5
GO:0009581 detection of external stimulus 3.583128e-5
GO:0046849 bone remodeling 3.658653e-5
GO:0002757 immune response-activating signal transduction 3.674976e-5
GO:0031111 negative regulation of microtubule polymerization or depolymerization 3.743376e-5
GO:0048534 hemopoietic or lymphoid organ development 3.771153e-5
GO:0002688 regulation of leukocyte chemotaxis 3.834700e-5
GO:0045597 positive regulation of cell differentiation 3.835703e-5
GO:0007219 Notch signaling pathway 3.904492e-5
GO:0009895 negative regulation of catabolic process 3.951702e-5
GO:0070482 response to oxygen levels 3.988521e-5
GO:0031116 positive regulation of microtubule polymerization 3.995981e-5
GO:0009612 response to mechanical stimulus 4.235438e-5
GO:0045621 positive regulation of lymphocyte differentiation 4.242326e-5
GO:0042981 regulation of apoptosis 4.289866e-5
GO:0046822 regulation of nucleocytoplasmic transport 4.360303e-5
GO:2000097 regulation of smooth muscle cell-matrix adhesion 4.444303e-5
GO:0055009 atrial cardiac muscle tissue morphogenesis 4.454871e-5
GO:0043409 negative regulation of MAPKKK cascade 4.546593e-5
GO:0050880 regulation of blood vessel size 4.603164e-5
GO:0060402 calcium ion transport into cytosol 4.651242e-5
GO:0001101 response to acid 4.681146e-5
GO:0002685 regulation of leukocyte migration 4.711795e-5
GO:2000286 receptor internalization involved in canonical Wnt receptor signaling pathway 4.766313e-5
GO:0016056 rhodopsin mediated signaling pathway 4.766313e-5
GO:0030224 monocyte differentiation 4.911366e-5
GO:0050954 sensory perception of mechanical stimulus 5.056241e-5
GO:0031114 regulation of microtubule depolymerization 5.060271e-5
GO:0042127 regulation of cell proliferation 5.258960e-5
GO:0048858 cell projection morphogenesis 5.341937e-5
GO:0043615 astrocyte cell migration 5.386688e-5
GO:0005513 detection of calcium ion 5.399869e-5
GO:0031581 hemidesmosome assembly 5.417045e-5
GO:0034599 cellular response to oxidative stress 5.479227e-5
GO:0030225 macrophage differentiation 5.517663e-5
GO:0021537 telencephalon development 5.684879e-5
GO:0043200 response to amino acid stimulus 5.726173e-5
GO:0010212 response to ionizing radiation 5.746001e-5
GO:0002690 positive regulation of leukocyte chemotaxis 5.751333e-5
GO:0045859 regulation of protein kinase activity 5.757747e-5
GO:0006820 anion transport 5.776875e-5
GO:0001963 synaptic transmission, dopaminergic 5.794863e-5
GO:0051353 positive regulation of oxidoreductase activity 5.820953e-5
GO:0042325 regulation of phosphorylation 5.949792e-5
GO:0008090 retrograde axon cargo transport 6.142922e-5
GO:0051223 regulation of protein transport 6.149688e-5
GO:0031281 positive regulation of cyclase activity 6.176309e-5
GO:0070838 divalent metal ion transport 6.292951e-5
GO:0051349 positive regulation of lyase activity 6.437737e-5
GO:0050818 regulation of coagulation 6.476925e-5
GO:0048669 collateral sprouting in absence of injury 6.498831e-5
GO:0045730 respiratory burst 6.626684e-5
GO:0032768 regulation of monooxygenase activity 6.755023e-5
GO:0010038 response to metal ion 6.988389e-5
GO:0008217 regulation of blood pressure 7.029630e-5
GO:0045428 regulation of nitric oxide biosynthetic process 7.127303e-5
GO:0006817 phosphate ion transport 7.141431e-5
GO:0050878 regulation of body fluid levels 7.207541e-5
GO:0090026 positive regulation of monocyte chemotaxis 7.230969e-5
GO:0021794 thalamus development 7.230969e-5
GO:0021670 lateral ventricle development 7.324538e-5
GO:0032990 cell part morphogenesis 7.454210e-5
GO:0051146 striated muscle cell differentiation 7.512834e-5
GO:0035588 G-protein coupled purinergic receptor signaling pathway 7.559672e-5
GO:0009582 detection of abiotic stimulus 7.621001e-5
GO:0019836 hemolysis by symbiont of host erythrocytes 7.680378e-5
GO:0055098 response to low-density lipoprotein particle stimulus 7.731200e-5
GO:0032790 ribosome disassembly 7.822343e-5
GO:0035684 helper T cell extravasation 7.838547e-5
GO:0031295 T cell costimulation 7.948405e-5
GO:0007409 axonogenesis 8.018738e-5
GO:0051532 regulation of NFAT protein import into nucleus 8.174455e-5
GO:0006586 indolalkylamine metabolic process 8.207005e-5
GO:0071896 protein localization to adherens junction 8.236666e-5
GO:0046661 male sex differentiation 8.483183e-5
GO:0014888 striated muscle adaptation 8.562038e-5
GO:2000098 negative regulation of smooth muscle cell-matrix adhesion 9.040096e-5
GO:0071258 cellular response to gravity 9.040096e-5
GO:0035491 positive regulation of leukotriene production involved in inflammatory response 9.040096e-5
GO:0061044 negative regulation of vascular wound healing 9.040096e-5
GO:0022602 ovulation cycle process 9.071557e-5
GO:2000114 regulation of establishment of cell polarity 9.074901e-5
GO:0048260 positive regulation of receptor-mediated endocytosis 9.208908e-5
GO:0032890 regulation of organic acid transport 9.270332e-5
GO:0060326 cell chemotaxis 9.311088e-5
GO:0007026 negative regulation of microtubule depolymerization 9.379063e-5
GO:0043067 regulation of programmed cell death 9.463734e-5


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling 6.993657e-21
GO:0055090 acylglycerol homeostasis 4.444869e-19
GO:0002227 innate immune response in mucosa 1.893747e-18
GO:0050896 response to stimulus 3.347527e-18
GO:0006952 defense response 8.900548e-17
GO:0006955 immune response 1.174981e-16
GO:0006982 response to lipid hydroperoxide 3.837682e-16
GO:0006810 transport 2.072272e-14
GO:0002684 positive regulation of immune system process 3.359528e-14
GO:0051234 establishment of localization 7.572162e-14
GO:0002251 organ or tissue specific immune response 2.312049e-13
GO:0006950 response to stress 2.533881e-13
GO:0002385 mucosal immune response 3.884021e-13
GO:0002376 immune system process 9.651746e-13
GO:0050748 negative regulation of lipoprotein metabolic process 1.194090e-11
GO:0034605 cellular response to heat 3.920462e-11
GO:0009611 response to wounding 5.319509e-11
GO:0034372 very-low-density lipoprotein particle remodeling 7.554528e-11
GO:0034370 triglyceride-rich lipoprotein particle remodeling 8.470984e-11
GO:0010627 regulation of intracellular protein kinase cascade 8.636659e-11
GO:0051179 localization 1.002760e-10
GO:0010898 positive regulation of triglyceride catabolic process 1.371532e-10
GO:0051716 cellular response to stimulus 1.570731e-10
GO:0002697 regulation of immune effector process 2.137676e-10
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 2.177859e-10
GO:0046903 secretion 2.562139e-10
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 2.852011e-10
GO:0050865 regulation of cell activation 9.749256e-10
GO:0050778 positive regulation of immune response 1.194281e-9
GO:0032946 positive regulation of mononuclear cell proliferation 1.284372e-9
GO:0070665 positive regulation of leukocyte proliferation 1.297959e-9
GO:0050776 regulation of immune response 1.529158e-9
GO:0034442 regulation of lipoprotein oxidation 1.585588e-9
GO:0031017 exocrine pancreas development 1.934808e-9
GO:0050671 positive regulation of lymphocyte proliferation 2.108168e-9
GO:0010817 regulation of hormone levels 2.492467e-9
GO:0007154 cell communication 2.746113e-9
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 3.347693e-9
GO:0006629 lipid metabolic process 3.551200e-9
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 3.630420e-9
GO:0023052 signaling 3.894214e-9
GO:0050864 regulation of B cell activation 4.554582e-9
GO:0007254 JNK cascade 5.286482e-9
GO:0043408 regulation of MAPKKK cascade 5.601100e-9
GO:0002694 regulation of leukocyte activation 5.635043e-9
GO:0042060 wound healing 5.839353e-9
GO:0033194 response to hydroperoxide 6.176419e-9
GO:0080134 regulation of response to stress 6.622029e-9
GO:0032940 secretion by cell 7.454261e-9
GO:0002703 regulation of leukocyte mediated immunity 8.354227e-9
GO:0009914 hormone transport 8.521449e-9
GO:0006691 leukotriene metabolic process 1.021090e-8
GO:0048584 positive regulation of response to stimulus 1.092172e-8
GO:0035458 cellular response to interferon-beta 1.280747e-8
GO:0042102 positive regulation of T cell proliferation 1.436716e-8
GO:0031098 stress-activated protein kinase signaling cascade 1.556346e-8
GO:0010832 negative regulation of myotube differentiation 1.582030e-8
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 1.905878e-8
GO:0002682 regulation of immune system process 2.066047e-8
GO:0007165 signal transduction 2.305257e-8
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2.389384e-8
GO:0002706 regulation of lymphocyte mediated immunity 2.982071e-8
GO:0065008 regulation of biological quality 3.002636e-8
GO:0070663 regulation of leukocyte proliferation 3.623362e-8
GO:0001817 regulation of cytokine production 4.946847e-8
GO:0002820 negative regulation of adaptive immune response 5.234331e-8
GO:0042832 defense response to protozoan 5.542866e-8
GO:0032944 regulation of mononuclear cell proliferation 6.918467e-8
GO:0042246 tissue regeneration 7.148301e-8
GO:0050746 regulation of lipoprotein metabolic process 8.197605e-8
GO:0008624 induction of apoptosis by extracellular signals 8.286250e-8
GO:0090208 positive regulation of triglyceride metabolic process 8.291768e-8
GO:0042035 regulation of cytokine biosynthetic process 8.515629e-8
GO:0048583 regulation of response to stimulus 8.856834e-8
GO:0050670 regulation of lymphocyte proliferation 1.032811e-7
GO:0051704 multi-organism process 1.035889e-7
GO:0032814 regulation of natural killer cell activation 1.071680e-7
GO:0050854 regulation of antigen receptor-mediated signaling pathway 1.141537e-7
GO:0061113 pancreas morphogenesis 1.182274e-7
GO:0023061 signal release 1.322710e-7
GO:0002707 negative regulation of lymphocyte mediated immunity 1.704912e-7
GO:0051006 positive regulation of lipoprotein lipase activity 1.985763e-7
GO:0032101 regulation of response to external stimulus 2.203890e-7
GO:0000018 regulation of DNA recombination 2.891450e-7
GO:0042744 hydrogen peroxide catabolic process 2.901882e-7
GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 3.009840e-7
GO:0002268 follicular dendritic cell differentiation 3.756944e-7
GO:0001562 response to protozoan 4.228947e-7
GO:0030300 regulation of intestinal cholesterol absorption 4.778107e-7
GO:0031100 organ regeneration 4.807077e-7
GO:0071702 organic substance transport 5.661195e-7
GO:0051049 regulation of transport 5.962833e-7
GO:0002521 leukocyte differentiation 6.522287e-7
GO:0019370 leukotriene biosynthetic process 6.680327e-7
GO:0001775 cell activation 6.736447e-7
GO:0031099 regeneration 6.776625e-7
GO:0008616 queuosine biosynthetic process 7.824558e-7
GO:0046456 icosanoid biosynthetic process 8.182041e-7
GO:0007159 leukocyte cell-cell adhesion 8.343261e-7
GO:0010740 positive regulation of intracellular protein kinase cascade 8.863639e-7
GO:0007257 activation of JUN kinase activity 9.796197e-7
GO:0000165 MAPKKK cascade 1.172776e-6
GO:0009896 positive regulation of catabolic process 1.225530e-6
GO:0042448 progesterone metabolic process 1.275755e-6
GO:0009266 response to temperature stimulus 1.280674e-6
GO:0043069 negative regulation of programmed cell death 1.340969e-6
GO:0060548 negative regulation of cell death 1.373251e-6
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 1.433897e-6
GO:0042108 positive regulation of cytokine biosynthetic process 1.497303e-6
GO:0042327 positive regulation of phosphorylation 1.575006e-6
GO:0007166 cell surface receptor linked signaling pathway 1.659114e-6
GO:0051249 regulation of lymphocyte activation 1.707944e-6
GO:0002698 negative regulation of immune effector process 1.754427e-6
GO:0030431 sleep 1.784960e-6
GO:0035634 response to stilbenoid 1.845537e-6
GO:0009408 response to heat 1.989290e-6
GO:0031347 regulation of defense response 2.015490e-6
GO:0043066 negative regulation of apoptosis 2.228166e-6
GO:0032879 regulation of localization 2.312888e-6
GO:0051707 response to other organism 2.367115e-6
GO:0006954 inflammatory response 2.392939e-6
GO:0010941 regulation of cell death 2.594613e-6
GO:0046879 hormone secretion 2.680798e-6
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 2.910280e-6
GO:0051251 positive regulation of lymphocyte activation 2.949073e-6
GO:0050860 negative regulation of T cell receptor signaling pathway 3.022529e-6
GO:0002921 negative regulation of humoral immune response 3.040096e-6
GO:0002687 positive regulation of leukocyte migration 3.190788e-6
GO:0009607 response to biotic stimulus 3.348820e-6
GO:0043067 regulation of programmed cell death 3.548201e-6
GO:0060157 urinary bladder development 3.566826e-6
GO:0002920 regulation of humoral immune response 3.584193e-6
GO:0032878 regulation of establishment or maintenance of cell polarity 3.647187e-6
GO:0050996 positive regulation of lipid catabolic process 3.713039e-6
GO:0060346 bone trabecula formation 3.756118e-6
GO:0010656 negative regulation of muscle cell apoptosis 3.977070e-6
GO:0006690 icosanoid metabolic process 3.980421e-6
GO:0050867 positive regulation of cell activation 3.994709e-6
GO:0010646 regulation of cell communication 5.074769e-6
GO:0002637 regulation of immunoglobulin production 5.130881e-6
GO:0006636 unsaturated fatty acid biosynthetic process 5.194480e-6
GO:0050856 regulation of T cell receptor signaling pathway 5.288492e-6
GO:0030183 B cell differentiation 5.323656e-6
GO:0032693 negative regulation of interleukin-10 production 5.630243e-6
GO:0040007 growth 6.059320e-6
GO:0019882 antigen processing and presentation 6.087424e-6
GO:0031331 positive regulation of cellular catabolic process 6.093699e-6
GO:0044255 cellular lipid metabolic process 6.111513e-6
GO:0046599 regulation of centriole replication 6.146465e-6
GO:0042981 regulation of apoptosis 6.207318e-6
GO:0042104 positive regulation of activated T cell proliferation 6.399258e-6
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.565306e-6
GO:0051239 regulation of multicellular organismal process 6.658481e-6
GO:0002819 regulation of adaptive immune response 6.680023e-6
GO:0010901 regulation of very-low-density lipoprotein particle remodeling 7.087236e-6
GO:0032102 negative regulation of response to external stimulus 7.220447e-6
GO:0010660 regulation of muscle cell apoptosis 8.283834e-6
GO:0001934 positive regulation of protein phosphorylation 8.694537e-6
GO:0009653 anatomical structure morphogenesis 8.789759e-6
GO:0070327 thyroid hormone transport 8.866028e-6
GO:0002696 positive regulation of leukocyte activation 9.426745e-6
GO:0001944 vasculature development 1.021207e-5
GO:0045910 negative regulation of DNA recombination 1.115142e-5
GO:0046660 female sex differentiation 1.130649e-5
GO:0043269 regulation of ion transport 1.239376e-5
GO:0007612 learning 1.284360e-5
GO:0002709 regulation of T cell mediated immunity 1.308281e-5
GO:0032732 positive regulation of interleukin-1 production 1.362164e-5
GO:0042129 regulation of T cell proliferation 1.399825e-5
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 1.412355e-5
GO:0010896 regulation of triglyceride catabolic process 1.417761e-5
GO:0051050 positive regulation of transport 1.434876e-5
GO:0046006 regulation of activated T cell proliferation 1.481480e-5
GO:0016579 protein deubiquitination 1.486259e-5
GO:0008617 guanosine metabolic process 1.539863e-5
GO:0009628 response to abiotic stimulus 1.592227e-5
GO:0045796 negative regulation of intestinal cholesterol absorption 1.600579e-5
GO:0010949 negative regulation of intestinal phytosterol absorption 1.600579e-5
GO:0032817 regulation of natural killer cell proliferation 1.610403e-5
GO:0002699 positive regulation of immune effector process 1.651576e-5
GO:0048513 organ development 1.732607e-5
GO:0070328 triglyceride homeostasis 1.735819e-5
GO:0035121 tail morphogenesis 1.735819e-5
GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway 1.742401e-5
GO:0032731 positive regulation of interleukin-1 beta production 1.768588e-5
GO:0045087 innate immune response 1.791635e-5
GO:0060299 negative regulation of sarcomere organization 1.838728e-5
GO:0060307 regulation of ventricular cardiomyocyte membrane repolarization 1.838728e-5
GO:0045937 positive regulation of phosphate metabolic process 1.886831e-5
GO:0000187 activation of MAPK activity 1.892333e-5
GO:0009101 glycoprotein biosynthetic process 1.902083e-5
GO:0015833 peptide transport 1.903395e-5
GO:0043270 positive regulation of ion transport 1.958471e-5
GO:0023051 regulation of signaling 2.078602e-5
GO:0050718 positive regulation of interleukin-1 beta secretion 2.116534e-5
GO:0010824 regulation of centrosome duplication 2.117814e-5
GO:0050830 defense response to Gram-positive bacterium 2.190025e-5
GO:0035964 COPI-coated vesicle budding 2.266584e-5
GO:0015914 phospholipid transport 2.343958e-5
GO:0045191 regulation of isotype switching 2.365552e-5
GO:0044058 regulation of digestive system process 2.400340e-5
GO:0007258 JUN phosphorylation 2.411211e-5
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 2.457689e-5
GO:0051928 positive regulation of calcium ion transport 2.504826e-5
GO:0046425 regulation of JAK-STAT cascade 2.590304e-5
GO:0042325 regulation of phosphorylation 2.593710e-5
GO:0002757 immune response-activating signal transduction 2.662362e-5
GO:0023056 positive regulation of signaling 2.665852e-5
GO:0042221 response to chemical stimulus 2.704575e-5
GO:0042743 hydrogen peroxide metabolic process 2.709036e-5
GO:0001560 regulation of cell growth by extracellular stimulus 2.876268e-5
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 2.890814e-5
GO:0045940 positive regulation of steroid metabolic process 2.981948e-5
GO:0031401 positive regulation of protein modification process 3.042022e-5
GO:0046427 positive regulation of JAK-STAT cascade 3.052523e-5
GO:0060026 convergent extension 3.052879e-5
GO:0046545 development of primary female sexual characteristics 3.140683e-5
GO:0045085 negative regulation of interleukin-2 biosynthetic process 3.169174e-5
GO:0002690 positive regulation of leukocyte chemotaxis 3.174516e-5
GO:0035567 non-canonical Wnt receptor signaling pathway 3.253923e-5
GO:0006631 fatty acid metabolic process 3.456721e-5
GO:0046328 regulation of JNK cascade 3.461373e-5
GO:0043471 regulation of cellular carbohydrate catabolic process 3.517965e-5
GO:0031343 positive regulation of cell killing 3.531776e-5
GO:0010647 positive regulation of cell communication 3.587680e-5
GO:0044240 multicellular organismal lipid catabolic process 3.748937e-5
GO:0051480 cytosolic calcium ion homeostasis 3.767484e-5
GO:0046889 positive regulation of lipid biosynthetic process 3.777030e-5
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein 4.000766e-5
GO:0035556 intracellular signal transduction 4.248071e-5
GO:0006916 anti-apoptosis 4.273832e-5
GO:0045577 regulation of B cell differentiation 4.311814e-5
GO:0009956 radial pattern formation 4.367654e-5
GO:0006869 lipid transport 4.464668e-5
GO:0030166 proteoglycan biosynthetic process 4.538615e-5
GO:0042446 hormone biosynthetic process 4.547889e-5
GO:0050851 antigen receptor-mediated signaling pathway 4.675746e-5
GO:0010876 lipid localization 4.913863e-5
GO:0042730 fibrinolysis 4.938322e-5
GO:0006029 proteoglycan metabolic process 5.019429e-5
GO:0060395 SMAD protein signal transduction 5.093801e-5
GO:0043410 positive regulation of MAPKKK cascade 5.241479e-5
GO:0043507 positive regulation of JUN kinase activity 5.286274e-5
GO:0060631 regulation of meiosis I 5.356952e-5
GO:0014904 myotube cell development 5.378791e-5
GO:0071560 cellular response to transforming growth factor beta stimulus 5.521429e-5
GO:0060837 blood vessel endothelial cell differentiation 5.560777e-5
GO:0007204 elevation of cytosolic calcium ion concentration 5.567848e-5
GO:0032816 positive regulation of natural killer cell activation 5.568971e-5
GO:0009966 regulation of signal transduction 5.629230e-5
GO:0002889 regulation of immunoglobulin mediated immune response 5.660717e-5
GO:0002710 negative regulation of T cell mediated immunity 5.705338e-5
GO:0010838 positive regulation of keratinocyte proliferation 5.719697e-5
GO:0002688 regulation of leukocyte chemotaxis 6.046930e-5
GO:0048302 regulation of isotype switching to IgG isotypes 6.061831e-5
GO:0046549 retinal cone cell development 6.148286e-5
GO:0006110 regulation of glycolysis 6.241604e-5
GO:0001909 leukocyte mediated cytotoxicity 6.380978e-5
GO:0002700 regulation of production of molecular mediator of immune response 6.416957e-5
GO:0008643 carbohydrate transport 6.418451e-5
GO:0010676 positive regulation of cellular carbohydrate metabolic process 6.679421e-5
GO:0090179 planar cell polarity pathway involved in neural tube closure 6.921878e-5
GO:0045821 positive regulation of glycolysis 6.921878e-5
GO:0002520 immune system development 6.947835e-5
GO:0050819 negative regulation of coagulation 6.962095e-5
GO:0045591 positive regulation of regulatory T cell differentiation 6.978349e-5
GO:0032621 interleukin-18 production 7.186062e-5
GO:0015939 pantothenate metabolic process 7.186062e-5
GO:0030540 female genitalia development 7.457029e-5
GO:0019220 regulation of phosphate metabolic process 7.483866e-5
GO:0032501 multicellular organismal process 7.496059e-5
GO:0045088 regulation of innate immune response 7.629539e-5
GO:0003008 system process 7.694923e-5
GO:0070302 regulation of stress-activated protein kinase signaling cascade 8.136226e-5
GO:0030098 lymphocyte differentiation 8.248247e-5
GO:0071305 cellular response to vitamin D 8.630607e-5
GO:0010765 positive regulation of sodium ion transport 8.700828e-5
GO:0071391 cellular response to estrogen stimulus 9.224719e-5
GO:0001932 regulation of protein phosphorylation 9.283436e-5
GO:0070875 positive regulation of glycogen metabolic process 9.492855e-5
GO:0032787 monocarboxylic acid metabolic process 9.701156e-5
GO:0042742 defense response to bacterium 9.737018e-5
GO:0002764 immune response-regulating signaling pathway 9.814846e-5
GO:0030097 hemopoiesis 9.929467e-5
GO:0043506 regulation of JUN kinase activity 9.935821e-5
GO:0007267 cell-cell signaling 1.008537e-4
GO:0048608 reproductive structure development 1.098383e-4
GO:0002467 germinal center formation 1.103977e-4
GO:0030104 water homeostasis 1.112105e-4
GO:0042036 negative regulation of cytokine biosynthetic process 1.119773e-4
GO:0006811 ion transport 1.120827e-4
GO:0009100 glycoprotein metabolic process 1.209403e-4
GO:0071559 response to transforming growth factor beta stimulus 1.213704e-4
GO:0055065 metal ion homeostasis 1.224281e-4
GO:0048534 hemopoietic or lymphoid organ development 1.234731e-4
GO:0046885 regulation of hormone biosynthetic process 1.247380e-4
GO:0046967 cytosol to ER transport 1.278478e-4
GO:0019060 intracellular transport of viral proteins in host cell 1.278478e-4
GO:0048293 regulation of isotype switching to IgE isotypes 1.359918e-4
GO:0050777 negative regulation of immune response 1.363204e-4
GO:0034599 cellular response to oxidative stress 1.365384e-4
GO:0031399 regulation of protein modification process 1.393454e-4
GO:0002708 positive regulation of lymphocyte mediated immunity 1.424487e-4
GO:0010738 regulation of protein kinase A signaling cascade 1.428819e-4
GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 1.469022e-4
GO:0045321 leukocyte activation 1.469307e-4
GO:0050847 progesterone receptor signaling pathway 1.475567e-4
GO:0002253 activation of immune response 1.508202e-4
GO:2000107 negative regulation of leukocyte apoptosis 1.538203e-4
GO:2000249 regulation of actin cytoskeleton reorganization 1.552009e-4
GO:0018993 somatic sex determination 1.559497e-4
GO:0032648 regulation of interferon-beta production 1.563550e-4
GO:0030262 apoptotic nuclear change 1.565151e-4
GO:0006826 iron ion transport 1.605232e-4
GO:0002429 immune response-activating cell surface receptor signaling pathway 1.616891e-4
GO:0044241 lipid digestion 1.619458e-4
GO:0044403 symbiosis, encompassing mutualism through parasitism 1.641454e-4
GO:0070848 response to growth factor stimulus 1.801064e-4
GO:0050818 regulation of coagulation 1.818502e-4
GO:0010893 positive regulation of steroid biosynthetic process 1.822914e-4
GO:0071392 cellular response to estradiol stimulus 1.834946e-4
GO:0010907 positive regulation of glucose metabolic process 1.854318e-4
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.881928e-4
GO:0046600 negative regulation of centriole replication 1.883976e-4
GO:0050871 positive regulation of B cell activation 1.908388e-4
GO:0014850 response to muscle activity 1.986248e-4
GO:0001819 positive regulation of cytokine production 1.988787e-4
GO:0010520 regulation of reciprocal meiotic recombination 2.070236e-4
GO:0009617 response to bacterium 2.109102e-4
GO:0046928 regulation of neurotransmitter secretion 2.119572e-4
GO:0032680 regulation of tumor necrosis factor production 2.156893e-4
GO:2000117 negative regulation of cysteine-type endopeptidase activity 2.171503e-4
GO:0060992 response to fungicide 2.181615e-4
GO:0006921 cellular component disassembly involved in apoptosis 2.226971e-4
GO:0009967 positive regulation of signal transduction 2.304115e-4
GO:0071363 cellular response to growth factor stimulus 2.332175e-4
GO:0050870 positive regulation of T cell activation 2.372909e-4
GO:0001910 regulation of leukocyte mediated cytotoxicity 2.393896e-4
GO:0060547 negative regulation of necrotic cell death 2.439690e-4
GO:0060741 prostate gland stromal morphogenesis 2.481605e-4
GO:0051096 positive regulation of helicase activity 2.481605e-4
GO:0010524 positive regulation of calcium ion transport into cytosol 2.499108e-4
GO:0031341 regulation of cell killing 2.502188e-4
GO:0009129 pyrimidine nucleoside monophosphate metabolic process 2.526204e-4
GO:0044057 regulation of system process 2.544478e-4
GO:0008210 estrogen metabolic process 2.718271e-4
GO:0001568 blood vessel development 2.728472e-4
GO:0032354 response to follicle-stimulating hormone stimulus 2.817728e-4
GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein 2.837716e-4
GO:0010033 response to organic substance 2.870800e-4
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 2.883517e-4
GO:0034754 cellular hormone metabolic process 2.928195e-4
GO:0009887 organ morphogenesis 2.930286e-4
GO:0007565 female pregnancy 2.943000e-4
GO:0071900 regulation of protein serine/threonine kinase activity 2.962305e-4
GO:0001906 cell killing 2.988594e-4
GO:0001837 epithelial to mesenchymal transition 2.994105e-4
GO:0002250 adaptive immune response 3.007758e-4
GO:0045073 regulation of chemokine biosynthetic process 3.025204e-4
GO:0042574 retinal metabolic process 3.027951e-4
GO:0001676 long-chain fatty acid metabolic process 3.035149e-4
GO:0009123 nucleoside monophosphate metabolic process 3.056824e-4
GO:0022602 ovulation cycle process 3.105960e-4
GO:0051385 response to mineralocorticoid stimulus 3.189296e-4
GO:0060343 trabecula formation 3.218467e-4
GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 3.267431e-4
GO:0032740 positive regulation of interleukin-17 production 3.287989e-4
GO:0009615 response to virus 3.304859e-4
GO:0042698 ovulation cycle 3.357391e-4
GO:2000505 regulation of energy homeostasis 3.399264e-4
GO:0080135 regulation of cellular response to stress 3.449597e-4
GO:0006812 cation transport 3.479252e-4
GO:0001922 B-1 B cell homeostasis 3.550896e-4
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 3.575553e-4
GO:0050727 regulation of inflammatory response 3.585212e-4
GO:0048856 anatomical structure development 3.592332e-4
GO:0006813 potassium ion transport 3.633562e-4
GO:0042759 long-chain fatty acid biosynthetic process 3.636549e-4
GO:0043405 regulation of MAP kinase activity 3.653412e-4
GO:0046341 CDP-diacylglycerol metabolic process 3.679447e-4
GO:0002677 negative regulation of chronic inflammatory response 3.679447e-4
GO:0042113 B cell activation 3.853160e-4
GO:0050869 negative regulation of B cell activation 3.866618e-4
GO:0032793 positive regulation of CREB transcription factor activity 3.880082e-4
GO:0002238 response to molecule of fungal origin 4.161764e-4
GO:0060444 branching involved in mammary gland duct morphogenesis 4.224509e-4
GO:0002768 immune response-regulating cell surface receptor signaling pathway 4.229069e-4
GO:0009306 protein secretion 4.349300e-4
GO:0051095 regulation of helicase activity 4.379547e-4
GO:0014894 response to denervation involved in regulation of muscle adaptation 4.379547e-4
GO:0042703 menstruation 4.461740e-4
GO:0019101 female somatic sex determination 4.461740e-4
GO:0070933 histone H4 deacetylation 4.525096e-4
GO:0035272 exocrine system development 4.551118e-4
GO:0051247 positive regulation of protein metabolic process 4.554753e-4
GO:0032729 positive regulation of interferon-gamma production 4.575468e-4
GO:0051412 response to corticosterone stimulus 4.622841e-4
GO:0072337 modified amino acid transport 4.635869e-4
GO:0046886 positive regulation of hormone biosynthetic process 4.731335e-4
GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity 4.733179e-4
GO:0022417 protein maturation by protein folding 4.733179e-4
GO:0048731 system development 4.773959e-4
GO:0045089 positive regulation of innate immune response 4.835359e-4
GO:0035644 phosphoanandamide dephosphorylation 4.924017e-4
GO:0072259 metanephric interstitial cell development 4.943858e-4
GO:0090094 metanephric cap mesenchymal cell proliferation involved in metanephros development 4.943858e-4
GO:0072184 renal vesicle progenitor cell differentiation 4.943858e-4
GO:0072208 metanephric smooth muscle tissue development 4.943858e-4
GO:0006550 isoleucine catabolic process 4.943858e-4
GO:0009098 leucine biosynthetic process 4.943858e-4
GO:0072168 specification of anterior mesonephric tubule identity 4.943858e-4
GO:0072169 specification of posterior mesonephric tubule identity 4.943858e-4
GO:0010959 regulation of metal ion transport 4.983172e-4
GO:0030001 metal ion transport 5.013239e-4
GO:0007167 enzyme linked receptor protein signaling pathway 5.042152e-4
GO:0033003 regulation of mast cell activation 5.096339e-4
GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 5.111812e-4
GO:0048294 negative regulation of isotype switching to IgE isotypes 5.130383e-4
GO:0002711 positive regulation of T cell mediated immunity 5.148337e-4
GO:0001839 neural plate morphogenesis 5.269854e-4
GO:0046590 embryonic leg morphogenesis 5.292392e-4
GO:0008635 activation of caspase activity by cytochrome c 5.333456e-4
GO:0045080 positive regulation of chemokine biosynthetic process 5.516283e-4
GO:0065005 protein-lipid complex assembly 5.567085e-4
GO:0001542 ovulation from ovarian follicle 5.567085e-4
GO:0048010 vascular endothelial growth factor receptor signaling pathway 5.685336e-4
GO:0050728 negative regulation of inflammatory response 5.764187e-4
GO:0071346 cellular response to interferon-gamma 5.825804e-4
GO:0051917 regulation of fibrinolysis 5.859150e-4
GO:0009409 response to cold 5.992251e-4
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 6.056572e-4
GO:0060457 negative regulation of digestive system process 6.100178e-4
GO:0036006 cellular response to macrophage colony-stimulating factor stimulus 6.100178e-4
GO:0019934 cGMP-mediated signaling 6.311238e-4
GO:0034392 negative regulation of smooth muscle cell apoptosis 6.574894e-4
GO:0015864 pyrimidine nucleoside transport 6.577059e-4
GO:0006198 cAMP catabolic process 6.626139e-4
GO:0043388 positive regulation of DNA binding 6.803465e-4
GO:0048518 positive regulation of biological process 6.850724e-4
GO:0071805 potassium ion transmembrane transport 6.859005e-4
GO:0048519 negative regulation of biological process 6.937999e-4
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.954711e-4
GO:0002685 regulation of leukocyte migration 7.064619e-4
GO:0060164 regulation of timing of neuron differentiation 7.068131e-4
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 7.300852e-4
GO:0007007 inner mitochondrial membrane organization 7.300852e-4
GO:0017156 calcium ion-dependent exocytosis 7.302833e-4
GO:0048514 blood vessel morphogenesis 7.353321e-4
GO:0045911 positive regulation of DNA recombination 7.431418e-4
GO:0030072 peptide hormone secretion 7.793972e-4
GO:0050878 regulation of body fluid levels 7.842373e-4
GO:0055074 calcium ion homeostasis 7.842525e-4
GO:0060926 pacemaker cell development 8.027507e-4
GO:0060932 His-Purkinje system cell differentiation 8.027507e-4
GO:0006875 cellular metal ion homeostasis 8.103208e-4
GO:0070646 protein modification by small protein removal 8.120982e-4
GO:0007596 blood coagulation 8.205881e-4
GO:0019433 triglyceride catabolic process 8.285392e-4
GO:0030850 prostate gland development 8.405702e-4
GO:0090030 regulation of steroid hormone biosynthetic process 8.411808e-4
GO:0045723 positive regulation of fatty acid biosynthetic process 8.497652e-4
GO:0090031 positive regulation of steroid hormone biosynthetic process 8.635915e-4
GO:2000507 positive regulation of energy homeostasis 8.731199e-4
GO:2000253 positive regulation of feeding behavior 8.731199e-4
GO:0051289 protein homotetramerization 8.775899e-4
GO:0018904 organic ether metabolic process 8.802991e-4
GO:0060029 convergent extension involved in organogenesis 8.839993e-4
GO:0042747 circadian sleep/wake cycle, REM sleep 8.901491e-4
GO:0032660 regulation of interleukin-17 production 8.935348e-4
GO:0048002 antigen processing and presentation of peptide antigen 9.224688e-4
GO:0048520 positive regulation of behavior 9.232429e-4
GO:0051240 positive regulation of multicellular organismal process 9.286662e-4
GO:0030321 transepithelial chloride transport 9.481108e-4
GO:2000691 negative regulation of cardiac muscle cell myoblast differentiation 9.697579e-4
GO:0007599 hemostasis 9.712993e-4
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 9.740855e-4
GO:0048585 negative regulation of response to stimulus 9.788065e-4
GO:0002790 peptide secretion 1.009296e-3
GO:0034391 regulation of smooth muscle cell apoptosis 1.028311e-3
GO:0014070 response to organic cyclic compound 1.047442e-3
GO:0050714 positive regulation of protein secretion 1.054688e-3
GO:0051047 positive regulation of secretion 1.057081e-3
GO:0006801 superoxide metabolic process 1.089200e-3
GO:2000119 negative regulation of sodium-dependent phosphate transport 1.097501e-3
GO:0008626 induction of apoptosis by granzyme 1.097501e-3
GO:0042535 positive regulation of tumor necrosis factor biosynthetic process 1.100123e-3
GO:0046649 lymphocyte activation 1.108448e-3
GO:0045589 regulation of regulatory T cell differentiation 1.116880e-3
GO:0030193 regulation of blood coagulation 1.143059e-3
GO:0045725 positive regulation of glycogen biosynthetic process 1.143759e-3
GO:0048008 platelet-derived growth factor receptor signaling pathway 1.155142e-3
GO:0030518 steroid hormone receptor signaling pathway 1.155175e-3
GO:0043409 negative regulation of MAPKKK cascade 1.167770e-3
GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis 1.172245e-3
GO:0035630 bone mineralization involved in bone maturation 1.172245e-3
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 1.174184e-3
GO:0070562 regulation of vitamin D receptor signaling pathway 1.174184e-3
GO:0070932 histone H3 deacetylation 1.174184e-3
GO:0035584 calcium-mediated signaling using intracellular calcium source 1.174184e-3
GO:0042445 hormone metabolic process 1.177667e-3