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Novel motif:83

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name:motif83_TTWTAAA

Association to promoter expression in human samplesSummary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon

link to source dataset
data




Association to promoter expression in mouse samples Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon

link to source dataset
data




GREAT analysis results for human Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data


GO IDGO Termp-value
GO:0009888 tissue development 3.551588e-25
GO:0050896 response to stimulus 4.653115e-24
GO:0048513 organ development 8.758533e-24
GO:0050794 regulation of cellular process 6.544777e-22
GO:0051716 cellular response to stimulus 2.006815e-21
GO:0048856 anatomical structure development 2.537354e-21
GO:0009611 response to wounding 1.228801e-20
GO:0048731 system development 4.463085e-20
GO:0032501 multicellular organismal process 1.201389e-19
GO:0032502 developmental process 1.425628e-18
GO:0042060 wound healing 7.758746e-18
GO:0042221 response to chemical stimulus 1.749544e-17
GO:0023052 signaling 5.373977e-17
GO:0065007 biological regulation 9.537781e-17
GO:0050789 regulation of biological process 3.424274e-16
GO:0007154 cell communication 3.748412e-16
GO:0006950 response to stress 5.903522e-16
GO:0072358 cardiovascular system development 1.409016e-15
GO:0007275 multicellular organismal development 1.730396e-15
GO:0030240 skeletal muscle thin filament assembly 2.551806e-15
GO:0007165 signal transduction 4.129891e-15
GO:0048468 cell development 4.304755e-15
GO:0048869 cellular developmental process 1.349486e-14
GO:0065008 regulation of biological quality 1.357532e-14
GO:0030154 cell differentiation 3.255434e-14
GO:0048769 sarcomerogenesis 5.630784e-14
GO:0051179 localization 2.346855e-13
GO:0007186 G-protein coupled receptor protein signaling pathway 2.403131e-13
GO:0055003 cardiac myofibril assembly 6.863913e-13
GO:0048646 anatomical structure formation involved in morphogenesis 6.994608e-13
GO:0007517 muscle organ development 7.088931e-13
GO:0014706 striated muscle tissue development 2.164649e-12
GO:0035051 cardiac cell differentiation 4.199618e-12
GO:0007596 blood coagulation 6.658973e-12
GO:0008152 metabolic process 6.945779e-12
GO:0019220 regulation of phosphate metabolic process 7.829675e-12
GO:0060537 muscle tissue development 9.104777e-12
GO:0007599 hemostasis 1.063189e-11
GO:0007076 mitotic chromosome condensation 1.305065e-11
GO:0002576 platelet degranulation 1.446914e-11
GO:0044237 cellular metabolic process 2.073130e-11
GO:0007166 cell surface receptor linked signaling pathway 2.107537e-11
GO:0006810 transport 2.913534e-11
GO:0001775 cell activation 3.276813e-11
GO:0003008 system process 3.661491e-11
GO:0014866 skeletal myofibril assembly 3.664658e-11
GO:0009987 cellular process 4.101427e-11
GO:0032989 cellular component morphogenesis 4.469110e-11
GO:0061061 muscle structure development 4.999407e-11
GO:0050878 regulation of body fluid levels 5.750633e-11
GO:0042325 regulation of phosphorylation 6.322178e-11
GO:0044260 cellular macromolecule metabolic process 7.035468e-11
GO:0050793 regulation of developmental process 1.004258e-10
GO:0051234 establishment of localization 1.039396e-10
GO:0018149 peptide cross-linking 1.450698e-10
GO:0048583 regulation of response to stimulus 1.604051e-10
GO:0030241 skeletal muscle myosin thick filament assembly 1.616671e-10
GO:0007507 heart development 1.619039e-10
GO:0045663 positive regulation of myoblast differentiation 1.810223e-10
GO:0048729 tissue morphogenesis 2.092042e-10
GO:0055007 cardiac muscle cell differentiation 2.443734e-10
GO:0001932 regulation of protein phosphorylation 2.917453e-10
GO:0009653 anatomical structure morphogenesis 3.352689e-10
GO:0045666 positive regulation of neuron differentiation 5.636125e-10
GO:0003007 heart morphogenesis 9.630628e-10
GO:0044238 primary metabolic process 1.225777e-9
GO:0001944 vasculature development 1.304923e-9
GO:0071559 response to transforming growth factor beta stimulus 1.327890e-9
GO:0070887 cellular response to chemical stimulus 1.467830e-9
GO:0055013 cardiac muscle cell development 1.806459e-9
GO:0010033 response to organic substance 1.847040e-9
GO:0001568 blood vessel development 3.140864e-9
GO:0007399 nervous system development 3.170511e-9
GO:0043170 macromolecule metabolic process 3.177740e-9
GO:0007417 central nervous system development 3.191571e-9
GO:0051592 response to calcium ion 3.365786e-9
GO:0043438 acetoacetic acid metabolic process 3.405098e-9
GO:0019605 butyrate metabolic process 3.421044e-9
GO:2000026 regulation of multicellular organismal development 3.494765e-9
GO:0000070 mitotic sister chromatid segregation 3.972937e-9
GO:0045137 development of primary sexual characteristics 4.046719e-9
GO:0000819 sister chromatid segregation 4.836334e-9
GO:0048608 reproductive structure development 5.766682e-9
GO:0045597 positive regulation of cell differentiation 5.932771e-9
GO:0010863 positive regulation of phospholipase C activity 7.394416e-9
GO:0016202 regulation of striated muscle tissue development 7.466101e-9
GO:0010038 response to metal ion 7.754398e-9
GO:0060736 prostate gland growth 8.375847e-9
GO:0071842 cellular component organization at cellular level 8.414952e-9
GO:0030168 platelet activation 8.628212e-9
GO:0006629 lipid metabolic process 1.210012e-8
GO:0007420 brain development 1.253262e-8
GO:2000741 positive regulation of mesenchymal stem cell differentiation 1.325264e-8
GO:0007160 cell-matrix adhesion 1.493106e-8
GO:0010517 regulation of phospholipase activity 1.670355e-8
GO:0007202 activation of phospholipase C activity 1.802726e-8
GO:0016043 cellular component organization 1.851868e-8
GO:0001655 urogenital system development 2.150698e-8
GO:0032268 regulation of cellular protein metabolic process 2.217667e-8
GO:0033036 macromolecule localization 2.287681e-8
GO:0015721 bile acid and bile salt transport 2.307198e-8
GO:0051094 positive regulation of developmental process 2.332536e-8
GO:0042438 melanin biosynthetic process 2.402922e-8
GO:0008285 negative regulation of cell proliferation 2.416423e-8
GO:0048634 regulation of muscle organ development 2.679116e-8
GO:0009719 response to endogenous stimulus 2.792187e-8
GO:0071495 cellular response to endogenous stimulus 3.629845e-8
GO:0007267 cell-cell signaling 4.048298e-8
GO:0071841 cellular component organization or biogenesis at cellular level 4.095888e-8
GO:0031399 regulation of protein modification process 4.332299e-8
GO:0030850 prostate gland development 4.732176e-8
GO:0071840 cellular component organization or biogenesis 5.191651e-8
GO:0045214 sarcomere organization 5.740038e-8
GO:0006068 ethanol catabolic process 5.872439e-8
GO:0045595 regulation of cell differentiation 6.168795e-8
GO:0030199 collagen fibril organization 7.425860e-8
GO:0046459 short-chain fatty acid metabolic process 8.564473e-8
GO:0008104 protein localization 9.205904e-8
GO:0000902 cell morphogenesis 9.546088e-8
GO:0060740 prostate gland epithelium morphogenesis 9.592316e-8
GO:0006582 melanin metabolic process 9.966122e-8
GO:0048522 positive regulation of cellular process 1.092869e-7
GO:0010518 positive regulation of phospholipase activity 1.232675e-7
GO:0008406 gonad development 1.236503e-7
GO:0048565 digestive tract development 1.295833e-7
GO:0060068 vagina development 1.440072e-7
GO:0046546 development of primary male sexual characteristics 1.477159e-7
GO:0031323 regulation of cellular metabolic process 1.657193e-7
GO:0060512 prostate gland morphogenesis 1.746795e-7
GO:0060429 epithelium development 1.761862e-7
GO:0060011 Sertoli cell proliferation 1.762158e-7
GO:0044255 cellular lipid metabolic process 2.029984e-7
GO:0033382 maintenance of granzyme B location in T cell secretory granule 2.089969e-7
GO:0033373 maintenance of protease location in mast cell secretory granule 2.089969e-7
GO:0048747 muscle fiber development 2.147056e-7
GO:0051970 negative regulation of transmission of nerve impulse 2.234675e-7
GO:0072507 divalent inorganic cation homeostasis 2.372249e-7
GO:0045661 regulation of myoblast differentiation 2.502020e-7
GO:0019748 secondary metabolic process 2.506535e-7
GO:2000739 regulation of mesenchymal stem cell differentiation 2.530189e-7
GO:0060191 regulation of lipase activity 2.539008e-7
GO:0048519 negative regulation of biological process 2.663678e-7
GO:0006805 xenobiotic metabolic process 2.764375e-7
GO:0019222 regulation of metabolic process 2.824935e-7
GO:0006366 transcription from RNA polymerase II promoter 2.843130e-7
GO:0022008 neurogenesis 2.912170e-7
GO:0048699 generation of neurons 2.967507e-7
GO:0051153 regulation of striated muscle cell differentiation 2.975380e-7
GO:0050907 detection of chemical stimulus involved in sensory perception 3.017372e-7
GO:0030182 neuron differentiation 3.240960e-7
GO:0043408 regulation of MAPKKK cascade 3.486031e-7
GO:0007548 sex differentiation 3.572238e-7
GO:0045785 positive regulation of cell adhesion 3.633868e-7
GO:0048589 developmental growth 3.807540e-7
GO:0007519 skeletal muscle tissue development 3.924351e-7
GO:0032514 positive regulation of protein phosphatase type 2B activity 4.071368e-7
GO:0048742 regulation of skeletal muscle fiber development 4.327328e-7
GO:0006029 proteoglycan metabolic process 4.520583e-7
GO:0051239 regulation of multicellular organismal process 4.559020e-7
GO:0031032 actomyosin structure organization 4.622593e-7
GO:0010811 positive regulation of cell-substrate adhesion 4.632626e-7
GO:0048523 negative regulation of cellular process 4.680169e-7
GO:0009966 regulation of signal transduction 4.805516e-7
GO:0014031 mesenchymal cell development 4.811027e-7
GO:0071103 DNA conformation change 5.069608e-7
GO:0043473 pigmentation 5.656090e-7
GO:0006887 exocytosis 5.784980e-7
GO:0030098 lymphocyte differentiation 5.804211e-7
GO:0006464 protein modification process 5.957899e-7
GO:0055074 calcium ion homeostasis 6.123228e-7
GO:0060193 positive regulation of lipase activity 6.189771e-7
GO:0009410 response to xenobiotic stimulus 6.408296e-7
GO:0042692 muscle cell differentiation 6.543053e-7
GO:0048518 positive regulation of biological process 6.610914e-7
GO:0023051 regulation of signaling 6.862624e-7
GO:0050805 negative regulation of synaptic transmission 7.182017e-7
GO:0048066 developmental pigmentation 7.424854e-7
GO:0071466 cellular response to xenobiotic stimulus 7.558034e-7
GO:0048514 blood vessel morphogenesis 7.785418e-7
GO:0090286 cytoskeletal anchoring at nuclear membrane 7.943550e-7
GO:0048739 cardiac muscle fiber development 8.672025e-7
GO:0071560 cellular response to transforming growth factor beta stimulus 9.505773e-7
GO:0048641 regulation of skeletal muscle tissue development 1.151339e-6
GO:0009617 response to bacterium 1.259509e-6
GO:0031645 negative regulation of neurological system process 1.302479e-6
GO:0002520 immune system development 1.420160e-6
GO:0000186 activation of MAPKK activity 1.474268e-6
GO:0010927 cellular component assembly involved in morphogenesis 1.518261e-6
GO:0051641 cellular localization 1.564813e-6
GO:0016567 protein ubiquitination 1.575370e-6
GO:0042246 tissue regeneration 1.685325e-6
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 1.687894e-6
GO:0072503 cellular divalent inorganic cation homeostasis 1.718222e-6
GO:0042113 B cell activation 1.740664e-6
GO:0031589 cell-substrate adhesion 1.761183e-6
GO:0055002 striated muscle cell development 1.821822e-6
GO:0046826 negative regulation of protein export from nucleus 1.829829e-6
GO:0048304 positive regulation of isotype switching to IgG isotypes 1.877538e-6
GO:0007059 chromosome segregation 2.037636e-6
GO:0008584 male gonad development 2.137507e-6
GO:0030183 B cell differentiation 2.281777e-6
GO:0090270 regulation of fibroblast growth factor production 2.368011e-6
GO:0016331 morphogenesis of embryonic epithelium 2.420619e-6
GO:0001841 neural tube formation 2.487272e-6
GO:0070493 thrombin receptor signaling pathway 2.605488e-6
GO:0043412 macromolecule modification 2.633659e-6
GO:0055123 digestive system development 2.701017e-6
GO:0044267 cellular protein metabolic process 2.715892e-6
GO:0008038 neuron recognition 2.743701e-6
GO:0046661 male sex differentiation 2.765999e-6
GO:0060255 regulation of macromolecule metabolic process 2.782481e-6
GO:0032940 secretion by cell 2.894254e-6
GO:0002009 morphogenesis of an epithelium 2.944917e-6
GO:0055114 oxidation-reduction process 2.987745e-6
GO:0019932 second-messenger-mediated signaling 3.020724e-6
GO:0042127 regulation of cell proliferation 3.122131e-6
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 3.209391e-6
GO:0007368 determination of left/right symmetry 3.217967e-6
GO:0048386 positive regulation of retinoic acid receptor signaling pathway 3.522422e-6
GO:0060538 skeletal muscle organ development 3.586822e-6
GO:0008202 steroid metabolic process 3.677006e-6
GO:0060317 cardiac epithelial to mesenchymal transition 3.721343e-6
GO:0051338 regulation of transferase activity 3.970158e-6
GO:0006874 cellular calcium ion homeostasis 3.998712e-6
GO:0035115 embryonic forelimb morphogenesis 4.177442e-6
GO:0032147 activation of protein kinase activity 4.245376e-6
GO:0048762 mesenchymal cell differentiation 4.260871e-6
GO:0040011 locomotion 4.419944e-6
GO:0055008 cardiac muscle tissue morphogenesis 4.439565e-6
GO:0001654 eye development 4.503487e-6
GO:0090292 nuclear matrix anchoring at nuclear membrane 4.541866e-6
GO:0070252 actin-mediated cell contraction 4.553161e-6
GO:0032879 regulation of localization 4.648341e-6
GO:0048534 hemopoietic or lymphoid organ development 4.658971e-6
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 5.016365e-6
GO:0030097 hemopoiesis 5.138619e-6
GO:0080090 regulation of primary metabolic process 5.575887e-6
GO:0048738 cardiac muscle tissue development 5.653792e-6
GO:0000904 cell morphogenesis involved in differentiation 5.677554e-6
GO:0048385 regulation of retinoic acid receptor signaling pathway 5.879934e-6
GO:0045664 regulation of neuron differentiation 5.913462e-6
GO:0060442 branching involved in prostate gland morphogenesis 6.025975e-6
GO:0032870 cellular response to hormone stimulus 6.144985e-6
GO:0042180 cellular ketone metabolic process 6.174293e-6
GO:0045165 cell fate commitment 6.432427e-6
GO:0032990 cell part morphogenesis 6.515618e-6
GO:0060525 prostate glandular acinus development 6.516101e-6
GO:0060284 regulation of cell development 7.144269e-6
GO:0006796 phosphate-containing compound metabolic process 7.215931e-6
GO:0003401 axis elongation 7.241794e-6
GO:0007229 integrin-mediated signaling pathway 7.973585e-6
GO:0014910 regulation of smooth muscle cell migration 8.004591e-6
GO:0006928 cellular component movement 8.080288e-6
GO:0061008 hepaticobiliary system development 8.128346e-6
GO:0055080 cation homeostasis 8.462439e-6
GO:0046836 glycolipid transport 8.844050e-6
GO:0090304 nucleic acid metabolic process 8.881122e-6
GO:0065009 regulation of molecular function 8.974800e-6
GO:0009799 specification of symmetry 9.123827e-6
GO:0060737 prostate gland morphogenetic growth 9.140365e-6
GO:0032446 protein modification by small protein conjugation 9.141884e-6
GO:0048858 cell projection morphogenesis 9.226558e-6
GO:0009855 determination of bilateral symmetry 9.530115e-6
GO:0007040 lysosome organization 9.551555e-6
GO:0030261 chromosome condensation 9.793592e-6
GO:0050654 chondroitin sulfate proteoglycan metabolic process 9.847942e-6
GO:0080135 regulation of cellular response to stress 9.939643e-6
GO:0009887 organ morphogenesis 1.009613e-5
GO:0009725 response to hormone stimulus 1.041536e-5
GO:0002376 immune system process 1.048775e-5
GO:0003006 developmental process involved in reproduction 1.071390e-5
GO:0051480 cytosolic calcium ion homeostasis 1.103587e-5
GO:0061036 positive regulation of cartilage development 1.113581e-5
GO:0040012 regulation of locomotion 1.138834e-5
GO:0043549 regulation of kinase activity 1.248514e-5
GO:0007033 vacuole organization 1.262600e-5
GO:0050877 neurological system process 1.268006e-5
GO:0007204 elevation of cytosolic calcium ion concentration 1.304751e-5
GO:0030049 muscle filament sliding 1.340107e-5
GO:0009593 detection of chemical stimulus 1.431681e-5
GO:0021915 neural tube development 1.436045e-5
GO:0051146 striated muscle cell differentiation 1.437014e-5
GO:0006954 inflammatory response 1.438801e-5
GO:0008543 fibroblast growth factor receptor signaling pathway 1.510851e-5
GO:0033059 cellular pigmentation 1.521623e-5
GO:0048709 oligodendrocyte differentiation 1.546073e-5
GO:0009893 positive regulation of metabolic process 1.552840e-5
GO:0002683 negative regulation of immune system process 1.563328e-5
GO:0016198 axon choice point recognition 1.676140e-5
GO:0030239 myofibril assembly 1.693387e-5
GO:0050931 pigment cell differentiation 1.697919e-5
GO:0019752 carboxylic acid metabolic process 1.721326e-5
GO:0001889 liver development 1.745415e-5
GO:0001525 angiogenesis 1.751561e-5
GO:0060383 positive regulation of DNA strand elongation 1.810811e-5
GO:0032332 positive regulation of chondrocyte differentiation 1.906757e-5
GO:0060415 muscle tissue morphogenesis 1.945945e-5
GO:0010627 regulation of intracellular protein kinase cascade 2.003770e-5
GO:0006935 chemotaxis 2.167698e-5
GO:0060602 branch elongation of an epithelium 2.179386e-5
GO:0001838 embryonic epithelial tube formation 2.227898e-5
GO:0050790 regulation of catalytic activity 2.264303e-5
GO:0006082 organic acid metabolic process 2.298842e-5
GO:2000145 regulation of cell motility 2.314707e-5
GO:0050911 detection of chemical stimulus involved in sensory perception of smell 2.322915e-5
GO:0006323 DNA packaging 2.324792e-5
GO:0014033 neural crest cell differentiation 2.324822e-5
GO:0048584 positive regulation of response to stimulus 2.352731e-5
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 2.361000e-5
GO:0002430 complement receptor mediated signaling pathway 2.401372e-5
GO:0006952 defense response 2.462095e-5
GO:0010646 regulation of cell communication 2.463835e-5
GO:0048015 phosphatidylinositol-mediated signaling 2.487111e-5
GO:0055001 muscle cell development 2.513688e-5
GO:0070848 response to growth factor stimulus 2.546190e-5
GO:0047496 vesicle transport along microtubule 2.579558e-5
GO:0030728 ovulation 2.586747e-5
GO:0008206 bile acid metabolic process 2.671461e-5
GO:0008228 opsonization 2.696530e-5
GO:0044344 cellular response to fibroblast growth factor stimulus 2.727688e-5
GO:0060523 prostate epithelial cord elongation 2.781204e-5
GO:0090336 positive regulation of brown fat cell differentiation 2.797078e-5
GO:0090362 positive regulation of platelet-derived growth factor production 2.797078e-5
GO:0090271 positive regulation of fibroblast growth factor production 2.797078e-5
GO:0055065 metal ion homeostasis 2.802318e-5
GO:0045070 positive regulation of viral genome replication 2.859954e-5
GO:0046587 positive regulation of calcium-dependent cell-cell adhesion 2.864805e-5
GO:0007155 cell adhesion 2.870882e-5
GO:0010810 regulation of cell-substrate adhesion 2.922887e-5
GO:0006720 isoprenoid metabolic process 2.975333e-5
GO:0071671 regulation of smooth muscle cell chemotaxis 2.982121e-5
GO:0006833 water transport 3.018403e-5
GO:0032438 melanosome organization 3.131792e-5
GO:0051345 positive regulation of hydrolase activity 3.157173e-5
GO:0009072 aromatic amino acid family metabolic process 3.300016e-5
GO:0015722 canalicular bile acid transport 3.334912e-5
GO:0048812 neuron projection morphogenesis 3.373184e-5
GO:0031394 positive regulation of prostaglandin biosynthetic process 3.407772e-5
GO:0001764 neuron migration 3.423227e-5
GO:0006069 ethanol oxidation 3.608178e-5
GO:0022602 ovulation cycle process 3.622450e-5
GO:0048592 eye morphogenesis 3.662490e-5
GO:0046903 secretion 3.688261e-5
GO:0060174 limb bud formation 3.798287e-5
GO:0040017 positive regulation of locomotion 3.824584e-5
GO:0048878 chemical homeostasis 3.894917e-5
GO:0072175 epithelial tube formation 4.051711e-5
GO:0071310 cellular response to organic substance 4.080926e-5
GO:0002070 epithelial cell maturation 4.112256e-5
GO:0060485 mesenchyme development 4.216604e-5
GO:0042044 fluid transport 4.233251e-5
GO:0007525 somatic muscle development 4.446122e-5
GO:0097070 ductus arteriosus closure 4.542649e-5
GO:0051149 positive regulation of muscle cell differentiation 4.657718e-5
GO:0061033 secretion by lung epithelial cell involved in lung growth 4.700756e-5
GO:0010838 positive regulation of keratinocyte proliferation 4.700756e-5
GO:0032512 regulation of protein phosphatase type 2B activity 4.700756e-5
GO:0030155 regulation of cell adhesion 4.708154e-5
GO:0010604 positive regulation of macromolecule metabolic process 4.718211e-5
GO:0030900 forebrain development 5.029743e-5
GO:0001708 cell fate specification 5.063695e-5
GO:0035058 nonmotile primary cilium assembly 5.192886e-5
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 5.266235e-5
GO:0030204 chondroitin sulfate metabolic process 5.269023e-5
GO:0048753 pigment granule organization 5.342957e-5
GO:0045185 maintenance of protein location 5.480016e-5
GO:0009820 alkaloid metabolic process 5.563771e-5
GO:0060548 negative regulation of cell death 5.652480e-5
GO:0035556 intracellular signal transduction 5.674565e-5
GO:0006721 terpenoid metabolic process 5.774330e-5
GO:0008037 cell recognition 5.838946e-5
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation 5.841438e-5
GO:0051046 regulation of secretion 5.916874e-5
GO:0042698 ovulation cycle 5.932312e-5
GO:0050906 detection of stimulus involved in sensory perception 5.983487e-5
GO:0070168 negative regulation of biomineral tissue development 6.408830e-5
GO:0035136 forelimb morphogenesis 6.421871e-5
GO:0035148 tube formation 6.454541e-5
GO:0060638 mesenchymal-epithelial cell signaling 6.519538e-5
GO:0030003 cellular cation homeostasis 6.558063e-5
GO:0031325 positive regulation of cellular metabolic process 6.764966e-5
GO:0045923 positive regulation of fatty acid metabolic process 7.000653e-5
GO:0002521 leukocyte differentiation 7.156442e-5
GO:0001947 heart looping 7.181175e-5
GO:0071305 cellular response to vitamin D 7.501416e-5
GO:0051602 response to electrical stimulus 7.559681e-5
GO:0006875 cellular metal ion homeostasis 7.819105e-5
GO:0030335 positive regulation of cell migration 7.893920e-5
GO:0051649 establishment of localization in cell 8.193971e-5
GO:0032787 monocarboxylic acid metabolic process 8.383226e-5
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 8.475708e-5
GO:0051246 regulation of protein metabolic process 8.549443e-5
GO:0006775 fat-soluble vitamin metabolic process 8.608472e-5
GO:0055082 cellular chemical homeostasis 8.649194e-5
GO:0016477 cell migration 8.701670e-5
GO:0030334 regulation of cell migration 8.831311e-5
GO:0048667 cell morphogenesis involved in neuron differentiation 9.011489e-5
GO:0072383 plus-end-directed vesicle transport along microtubule 9.082390e-5
GO:0006072 glycerol-3-phosphate metabolic process 9.135022e-5
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste 9.246467e-5
GO:0045859 regulation of protein kinase activity 9.247019e-5
GO:0051336 regulation of hydrolase activity 9.363468e-5
GO:0072001 renal system development 9.440137e-5
GO:0016310 phosphorylation 9.465372e-5
GO:0010648 negative regulation of cell communication 9.778437e-5
GO:0007389 pattern specification process 1.020983e-4
GO:0060606 tube closure 1.038070e-4
GO:0070647 protein modification by small protein conjugation or removal 1.047743e-4
GO:0030522 intracellular receptor mediated signaling pathway 1.048071e-4
GO:0014032 neural crest cell development 1.080511e-4
GO:0032252 secretory granule localization 1.094796e-4
GO:0006583 melanin biosynthetic process from tyrosine 1.101486e-4
GO:0051270 regulation of cellular component movement 1.107758e-4
GO:2000027 regulation of organ morphogenesis 1.126159e-4
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching 1.149557e-4
GO:0046649 lymphocyte activation 1.176389e-4
GO:0010001 glial cell differentiation 1.176410e-4
GO:0023057 negative regulation of signaling 1.178095e-4
GO:0030048 actin filament-based movement 1.180601e-4
GO:0007618 mating 1.190859e-4
GO:0023056 positive regulation of signaling 1.230843e-4
GO:0051235 maintenance of location 1.232225e-4
GO:0030203 glycosaminoglycan metabolic process 1.239935e-4
GO:0006468 protein phosphorylation 1.243525e-4
GO:0048806 genitalia development 1.258903e-4
GO:0001843 neural tube closure 1.365500e-4
GO:2000147 positive regulation of cell motility 1.372290e-4
GO:0051272 positive regulation of cellular component movement 1.377696e-4
GO:0030502 negative regulation of bone mineralization 1.393001e-4
GO:0007567 parturition 1.406797e-4
GO:0003014 renal system process 1.412343e-4
GO:0043069 negative regulation of programmed cell death 1.422757e-4
GO:0070302 regulation of stress-activated protein kinase signaling cascade 1.430217e-4
GO:0048870 cell motility 1.432750e-4
GO:0032330 regulation of chondrocyte differentiation 1.473830e-4
GO:0021953 central nervous system neuron differentiation 1.486465e-4
GO:0060008 Sertoli cell differentiation 1.493107e-4
GO:0046292 formaldehyde metabolic process 1.500579e-4
GO:0007409 axonogenesis 1.501090e-4
GO:0046328 regulation of JNK cascade 1.531606e-4
GO:0048662 negative regulation of smooth muscle cell proliferation 1.541700e-4
GO:0021778 oligodendrocyte cell fate specification 1.550726e-4
GO:0043066 negative regulation of apoptosis 1.581863e-4
GO:0009082 branched chain family amino acid biosynthetic process 1.613776e-4
GO:0010232 vascular transport 1.644742e-4
GO:0006426 glycyl-tRNA aminoacylation 1.644742e-4
GO:0003408 optic cup formation involved in camera-type eye development 1.676050e-4
GO:0014912 negative regulation of smooth muscle cell migration 1.719169e-4
GO:0042063 gliogenesis 1.722112e-4
GO:0048683 regulation of collateral sprouting of intact axon in response to injury 1.779646e-4
GO:0032227 negative regulation of synaptic transmission, dopaminergic 1.779646e-4
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 1.781153e-4
GO:0051704 multi-organism process 1.837508e-4
GO:0052697 xenobiotic glucuronidation 1.837693e-4
GO:0070980 biphenyl catabolic process 1.837693e-4
GO:0051552 flavone metabolic process 1.837693e-4
GO:0052696 flavonoid glucuronidation 1.837693e-4
GO:0006789 bilirubin conjugation 1.837693e-4
GO:0051276 chromosome organization 1.838648e-4
GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway 1.892235e-4
GO:0050869 negative regulation of B cell activation 1.893842e-4
GO:0007600 sensory perception 1.922960e-4
GO:0010647 positive regulation of cell communication 1.950825e-4
GO:0021517 ventral spinal cord development 1.977494e-4
GO:0014020 primary neural tube formation 2.007932e-4
GO:0009083 branched chain family amino acid catabolic process 2.054851e-4
GO:0046854 phosphatidylinositol phosphorylation 2.069914e-4
GO:0015701 bicarbonate transport 2.080958e-4
GO:0051705 behavioral interaction between organisms 2.121376e-4
GO:0017144 drug metabolic process 2.177293e-4
GO:0042572 retinol metabolic process 2.226333e-4
GO:0009063 cellular amino acid catabolic process 2.248904e-4
GO:0050801 ion homeostasis 2.253785e-4
GO:0006916 anti-apoptosis 2.297629e-4
GO:0007030 Golgi organization 2.305892e-4
GO:0006807 nitrogen compound metabolic process 2.342604e-4
GO:0060900 embryonic camera-type eye formation 2.389179e-4
GO:0019359 nicotinamide nucleotide biosynthetic process 2.403357e-4
GO:0014911 positive regulation of smooth muscle cell migration 2.496165e-4
GO:0045767 regulation of anti-apoptosis 2.497129e-4
GO:0030318 melanocyte differentiation 2.557519e-4
GO:0051147 regulation of muscle cell differentiation 2.602976e-4
GO:0060562 epithelial tube morphogenesis 2.607300e-4
GO:0019441 tryptophan catabolic process to kynurenine 2.653683e-4
GO:0035588 G-protein coupled purinergic receptor signaling pathway 2.681907e-4
GO:0001822 kidney development 2.715645e-4
GO:0015031 protein transport 2.762266e-4
GO:0045884 regulation of survival gene product expression 2.858345e-4
GO:0060629 regulation of homologous chromosome segregation 2.876728e-4
GO:0051598 meiotic recombination checkpoint 2.876728e-4
GO:0006357 regulation of transcription from RNA polymerase II promoter 2.938873e-4
GO:0009081 branched chain family amino acid metabolic process 2.958390e-4
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 3.046129e-4
GO:0010834 telomere maintenance via telomere shortening 3.068912e-4
GO:0009435 NAD biosynthetic process 3.149828e-4
GO:0019538 protein metabolic process 3.175918e-4
GO:0019935 cyclic-nucleotide-mediated signaling 3.197546e-4
GO:0007157 heterophilic cell-cell adhesion 3.240413e-4
GO:0007156 homophilic cell adhesion 3.251453e-4
GO:0046329 negative regulation of JNK cascade 3.266290e-4


GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset
data

GO IDGO Termp-value
GO:0048513 organ development 1.808976e-13
GO:0048731 system development 4.299585e-10
GO:0048034 heme O biosynthetic process 4.638166e-10
GO:0002376 immune system process 1.118989e-9
GO:0048856 anatomical structure development 1.250776e-9
GO:0032817 regulation of natural killer cell proliferation 1.907130e-9
GO:0045321 leukocyte activation 2.899822e-9
GO:0006955 immune response 3.784219e-9
GO:0006014 D-ribose metabolic process 4.641627e-9
GO:0009052 pentose-phosphate shunt, non-oxidative branch 4.877888e-9
GO:0007275 multicellular organismal development 5.639174e-9
GO:0045445 myoblast differentiation 6.396210e-9
GO:0019693 ribose phosphate metabolic process 8.007014e-9
GO:0032502 developmental process 9.833989e-9
GO:0048584 positive regulation of response to stimulus 4.486255e-8
GO:0035295 tube development 4.637171e-8
GO:0043129 surfactant homeostasis 6.277334e-8
GO:0046649 lymphocyte activation 1.241560e-7
GO:0032501 multicellular organismal process 1.597222e-7
GO:0017004 cytochrome complex assembly 1.700353e-7
GO:0001775 cell activation 2.130608e-7
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway 2.348842e-7
GO:0043620 regulation of DNA-dependent transcription in response to stress 2.707415e-7
GO:0048520 positive regulation of behavior 4.152300e-7
GO:0050793 regulation of developmental process 5.337070e-7
GO:0032814 regulation of natural killer cell activation 6.289594e-7
GO:0045671 negative regulation of osteoclast differentiation 7.261108e-7
GO:0050930 induction of positive chemotaxis 7.543516e-7
GO:0006704 glucocorticoid biosynthetic process 8.932113e-7
GO:0050801 ion homeostasis 9.430192e-7
GO:0097091 synaptic vesicle clustering 9.572910e-7
GO:0097105 presynaptic membrane assembly 9.928011e-7
GO:0048534 hemopoietic or lymphoid organ development 1.026295e-6
GO:0051648 vesicle localization 1.072293e-6
GO:0009653 anatomical structure morphogenesis 1.179444e-6
GO:0002520 immune system development 1.211131e-6
GO:0007157 heterophilic cell-cell adhesion 1.373737e-6
GO:0010960 magnesium ion homeostasis 1.592705e-6
GO:0042110 T cell activation 1.651602e-6
GO:0030097 hemopoiesis 1.740987e-6
GO:0007158 neuron cell-cell adhesion 2.186516e-6
GO:0048869 cellular developmental process 2.254392e-6
GO:0042098 T cell proliferation 2.256846e-6
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 2.352002e-6
GO:0030098 lymphocyte differentiation 2.389761e-6
GO:0060412 ventricular septum morphogenesis 2.720274e-6
GO:0097090 presynaptic membrane organization 2.728061e-6
GO:0046651 lymphocyte proliferation 3.083682e-6
GO:0070661 leukocyte proliferation 3.155823e-6
GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity 3.667395e-6
GO:0002683 negative regulation of immune system process 3.789359e-6
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 4.111429e-6
GO:0035644 phosphoanandamide dephosphorylation 4.164330e-6
GO:0061053 somite development 4.794790e-6
GO:0051239 regulation of multicellular organismal process 4.910373e-6
GO:0016339 calcium-dependent cell-cell adhesion 4.998816e-6
GO:0043482 cellular pigment accumulation 5.270366e-6
GO:0006784 heme a biosynthetic process 5.843295e-6
GO:0097120 receptor localization to synapse 6.130990e-6
GO:0072578 neurotransmitter-gated ion channel clustering 6.130990e-6
GO:0016080 synaptic vesicle targeting 6.226505e-6
GO:0048878 chemical homeostasis 6.296007e-6
GO:0032943 mononuclear cell proliferation 6.598070e-6
GO:0030154 cell differentiation 6.801223e-6
GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 8.913038e-6
GO:2001051 positive regulation of tendon cell differentiation 8.946924e-6
GO:0021509 roof plate formation 8.946924e-6
GO:0002541 activation of plasma proteins involved in acute inflammatory response 9.943506e-6
GO:0043496 regulation of protein homodimerization activity 1.084445e-5
GO:0065008 regulation of biological quality 1.115212e-5
GO:0008207 C21-steroid hormone metabolic process 1.123388e-5
GO:0055080 cation homeostasis 1.152593e-5
GO:0003091 renal water homeostasis 1.164546e-5
GO:0055065 metal ion homeostasis 1.259901e-5
GO:0030217 T cell differentiation 1.263591e-5
GO:0007417 central nervous system development 1.287648e-5
GO:0048583 regulation of response to stimulus 1.289104e-5
GO:0006873 cellular ion homeostasis 1.331209e-5
GO:0051093 negative regulation of developmental process 1.488976e-5
GO:0002521 leukocyte differentiation 1.633281e-5
GO:0046620 regulation of organ growth 1.754438e-5
GO:0043476 pigment accumulation 1.792796e-5
GO:0050852 T cell receptor signaling pathway 1.836945e-5
GO:0097104 postsynaptic membrane assembly 1.887519e-5
GO:0097119 postsynaptic density protein 95 clustering 1.887519e-5
GO:0034754 cellular hormone metabolic process 1.991338e-5
GO:0050795 regulation of behavior 2.079218e-5
GO:0097115 neurexin clustering 2.110737e-5
GO:0007062 sister chromatid cohesion 2.114975e-5
GO:0002252 immune effector process 2.304594e-5
GO:0022602 ovulation cycle process 2.459914e-5
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 2.462782e-5
GO:0030514 negative regulation of BMP signaling pathway 2.648954e-5
GO:0032879 regulation of localization 2.938275e-5
GO:0048646 anatomical structure formation involved in morphogenesis 2.977150e-5
GO:0002768 immune response-regulating cell surface receptor signaling pathway 3.001987e-5
GO:0008284 positive regulation of cell proliferation 3.029390e-5
GO:0055082 cellular chemical homeostasis 3.367194e-5
GO:0032819 positive regulation of natural killer cell proliferation 3.543670e-5
GO:0042753 positive regulation of circadian rhythm 3.712764e-5
GO:0035590 purinergic nucleotide receptor signaling pathway 3.806755e-5
GO:2000463 positive regulation of excitatory postsynaptic membrane potential 4.320464e-5
GO:0046884 follicle-stimulating hormone secretion 4.694974e-5
GO:0032275 luteinizing hormone secretion 4.694974e-5
GO:0030278 regulation of ossification 4.737531e-5
GO:0090403 oxidative stress-induced premature senescence 4.884700e-5
GO:0003281 ventricular septum development 5.042824e-5
GO:0007399 nervous system development 5.150153e-5
GO:0001756 somitogenesis 5.171188e-5
GO:0046660 female sex differentiation 5.463360e-5
GO:0046545 development of primary female sexual characteristics 5.536810e-5
GO:0051240 positive regulation of multicellular organismal process 5.593222e-5
GO:0001944 vasculature development 5.757016e-5
GO:0002429 immune response-activating cell surface receptor signaling pathway 5.806345e-5
GO:0009888 tissue development 6.026934e-5
GO:0045176 apical protein localization 6.105322e-5
GO:0072395 signal transduction involved in cell cycle checkpoint 6.271750e-5
GO:2000026 regulation of multicellular organismal development 6.324755e-5
GO:0030071 regulation of mitotic metaphase/anaphase transition 6.358748e-5
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 6.399689e-5
GO:0002366 leukocyte activation involved in immune response 6.420163e-5
GO:0030888 regulation of B cell proliferation 6.467017e-5
GO:0055081 anion homeostasis 6.686304e-5
GO:0019321 pentose metabolic process 6.953898e-5
GO:0045666 positive regulation of neuron differentiation 7.131775e-5
GO:0042698 ovulation cycle 7.154355e-5
GO:0042445 hormone metabolic process 7.224949e-5
GO:0050851 antigen receptor-mediated signaling pathway 7.250660e-5
GO:0072404 signal transduction involved in G1/S transition checkpoint 7.819565e-5
GO:0045838 positive regulation of membrane potential 7.931437e-5
GO:0002051 osteoblast fate commitment 8.112694e-5
GO:0050670 regulation of lymphocyte proliferation 8.115435e-5
GO:0035418 protein localization to synapse 8.791605e-5
GO:0032655 regulation of interleukin-12 production 8.991471e-5
GO:2000466 negative regulation of glycogen (starch) synthase activity 9.065068e-5
GO:0021891 olfactory bulb interneuron development 9.752259e-5
GO:0001953 negative regulation of cell-matrix adhesion 9.845029e-5
GO:0034261 negative regulation of Ras GTPase activity 1.035201e-4
GO:0032944 regulation of mononuclear cell proliferation 1.054879e-4
GO:0002285 lymphocyte activation involved in immune response 1.060277e-4
GO:0045165 cell fate commitment 1.091890e-4
GO:0048598 embryonic morphogenesis 1.129284e-4
GO:0035588 G-protein coupled purinergic receptor signaling pathway 1.155611e-4
GO:0061302 smooth muscle cell-matrix adhesion 1.178672e-4
GO:0035623 renal glucose absorption 1.178672e-4
GO:0045668 negative regulation of osteoblast differentiation 1.194605e-4
GO:0032695 negative regulation of interleukin-12 production 1.210902e-4
GO:0048304 positive regulation of isotype switching to IgG isotypes 1.210902e-4
GO:0030003 cellular cation homeostasis 1.228709e-4
GO:0048625 myoblast cell fate commitment 1.231369e-4
GO:0042127 regulation of cell proliferation 1.260400e-4
GO:0050926 regulation of positive chemotaxis 1.268401e-4
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 1.280526e-4
GO:0006875 cellular metal ion homeostasis 1.284996e-4
GO:0048762 mesenchymal cell differentiation 1.341646e-4
GO:0051640 organelle localization 1.349787e-4
GO:0050927 positive regulation of positive chemotaxis 1.353471e-4
GO:0072358 cardiovascular system development 1.365287e-4
GO:0050871 positive regulation of B cell activation 1.388284e-4
GO:0035690 cellular response to drug 1.427377e-4
GO:0018298 protein-chromophore linkage 1.440842e-4
GO:0070663 regulation of leukocyte proliferation 1.527269e-4
GO:0043374 CD8-positive, alpha-beta T cell differentiation 1.532825e-4
GO:0001568 blood vessel development 1.586211e-4
GO:0002684 positive regulation of immune system process 1.595348e-4
GO:0001887 selenium compound metabolic process 1.599643e-4
GO:0050776 regulation of immune response 1.630043e-4
GO:0055078 sodium ion homeostasis 1.645308e-4
GO:0045596 negative regulation of cell differentiation 1.671848e-4
GO:0006098 pentose-phosphate shunt 1.704897e-4
GO:0060411 cardiac septum morphogenesis 1.721596e-4
GO:0014033 neural crest cell differentiation 1.735260e-4
GO:0001501 skeletal system development 1.770684e-4
GO:0008057 eye pigment granule organization 1.807403e-4
GO:0021889 olfactory bulb interneuron differentiation 1.850067e-4
GO:0006739 NADP metabolic process 1.866412e-4
GO:0030510 regulation of BMP signaling pathway 1.868152e-4
GO:0008354 germ cell migration 1.873779e-4
GO:0051250 negative regulation of lymphocyte activation 1.877530e-4
GO:0008585 female gonad development 1.877530e-4
GO:0048857 neural nucleus development 1.895497e-4
GO:0007420 brain development 1.931026e-4
GO:0042448 progesterone metabolic process 1.952847e-4
GO:0051586 positive regulation of dopamine uptake 1.975236e-4
GO:0060173 limb development 2.001985e-4
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 2.056558e-4
GO:0051971 positive regulation of transmission of nerve impulse 2.069943e-4
GO:0001525 angiogenesis 2.127792e-4
GO:0014031 mesenchymal cell development 2.225906e-4
GO:0045667 regulation of osteoblast differentiation 2.255247e-4
GO:0035810 positive regulation of urine volume 2.276007e-4
GO:0046851 negative regulation of bone remodeling 2.292332e-4
GO:0051650 establishment of vesicle localization 2.340834e-4
GO:0035108 limb morphogenesis 2.374935e-4
GO:0002682 regulation of immune system process 2.459638e-4
GO:0048854 brain morphogenesis 2.505573e-4
GO:0031290 retinal ganglion cell axon guidance 2.535815e-4
GO:0097070 ductus arteriosus closure 2.541260e-4
GO:0045842 positive regulation of mitotic metaphase/anaphase transition 2.541260e-4
GO:0061039 ovum-producing ovary development 2.570691e-4
GO:0051898 negative regulation of protein kinase B signaling cascade 2.586209e-4
GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis 2.666105e-4
GO:0019725 cellular homeostasis 2.677635e-4
GO:0055013 cardiac muscle cell development 2.715112e-4
GO:0071380 cellular response to prostaglandin E stimulus 2.847468e-4
GO:0045595 regulation of cell differentiation 2.867849e-4
GO:0010754 negative regulation of cGMP-mediated signaling 2.888061e-4
GO:0010751 negative regulation of nitric oxide mediated signal transduction 2.888061e-4
GO:0002605 negative regulation of dendritic cell antigen processing and presentation 2.888061e-4
GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.888061e-4
GO:0018149 peptide cross-linking 3.034246e-4
GO:0001941 postsynaptic membrane organization 3.079572e-4
GO:0001763 morphogenesis of a branching structure 3.083192e-4
GO:0003151 outflow tract morphogenesis 3.135145e-4
GO:0001952 regulation of cell-matrix adhesion 3.204247e-4
GO:0050921 positive regulation of chemotaxis 3.230277e-4
GO:0048514 blood vessel morphogenesis 3.248696e-4
GO:0003006 developmental process involved in reproduction 3.251114e-4
GO:0060134 prepulse inhibition 3.312365e-4
GO:0042113 B cell activation 3.376597e-4
GO:0051966 regulation of synaptic transmission, glutamatergic 3.565837e-4
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 3.763753e-4
GO:0071560 cellular response to transforming growth factor beta stimulus 3.772010e-4
GO:0000245 spliceosome assembly 3.795057e-4
GO:0000733 DNA strand renaturation 3.824231e-4
GO:0009162 deoxyribonucleoside monophosphate metabolic process 4.079185e-4
GO:0090074 negative regulation of protein homodimerization activity 4.079185e-4
GO:0033688 regulation of osteoblast proliferation 4.130509e-4
GO:0050778 positive regulation of immune response 4.132490e-4
GO:0010817 regulation of hormone levels 4.287881e-4
GO:0002764 immune response-regulating signaling pathway 4.542777e-4
GO:0097113 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering 4.564869e-4
GO:0009219 pyrimidine deoxyribonucleotide metabolic process 4.564869e-4
GO:0034104 negative regulation of tissue remodeling 4.577120e-4
GO:0006952 defense response 4.622698e-4
GO:0010749 regulation of nitric oxide mediated signal transduction 4.646540e-4
GO:0050806 positive regulation of synaptic transmission 4.658072e-4
GO:0030323 respiratory tube development 4.813491e-4
GO:0051607 defense response to virus 4.850990e-4
GO:0050891 multicellular organismal water homeostasis 4.884936e-4
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 5.030486e-4
GO:0019320 hexose catabolic process 5.098351e-4
GO:0043032 positive regulation of macrophage activation 5.141473e-4
GO:0071305 cellular response to vitamin D 5.195060e-4
GO:0030324 lung development 5.201405e-4
GO:0042592 homeostatic process 5.307625e-4
GO:0031646 positive regulation of neurological system process 5.444800e-4
GO:0031342 negative regulation of cell killing 5.456346e-4
GO:0071559 response to transforming growth factor beta stimulus 5.461433e-4
GO:0043009 chordate embryonic development 5.507898e-4
GO:0002757 immune response-activating signal transduction 5.528570e-4
GO:0040017 positive regulation of locomotion 5.572941e-4
GO:0045659 negative regulation of neutrophil differentiation 5.665523e-4
GO:0006925 inflammatory cell apoptosis 5.665523e-4
GO:0046621 negative regulation of organ growth 5.668766e-4
GO:0009264 deoxyribonucleotide catabolic process 5.816484e-4
GO:0002009 morphogenesis of an epithelium 5.816940e-4
GO:0030183 B cell differentiation 5.835488e-4
GO:0060174 limb bud formation 5.854825e-4
GO:0033373 maintenance of protease location in mast cell secretory granule 6.186984e-4
GO:0033382 maintenance of granzyme B location in T cell secretory granule 6.186984e-4
GO:0033363 secretory granule organization 6.284954e-4
GO:0000375 RNA splicing, via transesterification reactions 6.362825e-4
GO:0055006 cardiac cell development 6.481305e-4
GO:0007548 sex differentiation 6.483190e-4
GO:0032825 positive regulation of natural killer cell differentiation 6.562360e-4
GO:0051968 positive regulation of synaptic transmission, glutamatergic 6.619196e-4
GO:0072507 divalent inorganic cation homeostasis 6.678083e-4
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 6.703183e-4
GO:0046601 positive regulation of centriole replication 6.740060e-4
GO:0000398 nuclear mRNA splicing, via spliceosome 6.757374e-4
GO:0045638 negative regulation of myeloid cell differentiation 6.784058e-4
GO:0065007 biological regulation 6.903524e-4
GO:0035909 aorta morphogenesis 6.931260e-4
GO:0050864 regulation of B cell activation 6.964585e-4
GO:0043603 cellular amide metabolic process 7.016262e-4
GO:0006007 glucose catabolic process 7.065815e-4
GO:0055074 calcium ion homeostasis 7.121679e-4
GO:0010627 regulation of intracellular protein kinase cascade 7.138931e-4
GO:0051272 positive regulation of cellular component movement 7.208491e-4
GO:0060563 neuroepithelial cell differentiation 7.268526e-4
GO:0001841 neural tube formation 7.312399e-4
GO:0002011 morphogenesis of an epithelial sheet 7.355984e-4
GO:0032816 positive regulation of natural killer cell activation 7.593452e-4
GO:0002253 activation of immune response 7.938749e-4
GO:0071377 cellular response to glucagon stimulus 8.058168e-4
GO:0045348 positive regulation of MHC class II biosynthetic process 8.058168e-4
GO:0002066 columnar/cuboidal epithelial cell development 8.099970e-4
GO:0060485 mesenchyme development 8.113649e-4
GO:0031424 keratinization 8.428539e-4
GO:0009792 embryo development ending in birth or egg hatching 8.476739e-4
GO:0050679 positive regulation of epithelial cell proliferation 8.628320e-4
GO:0006953 acute-phase response 8.631239e-4
GO:0050678 regulation of epithelial cell proliferation 8.721166e-4
GO:0046365 monosaccharide catabolic process 8.882295e-4
GO:0043652 engulfment of apoptotic cell 8.898030e-4
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 9.037366e-4
GO:0019836 hemolysis by symbiont of host erythrocytes 9.135911e-4
GO:0035809 regulation of urine volume 9.281942e-4
GO:0015871 choline transport 9.454983e-4
GO:0044275 cellular carbohydrate catabolic process 9.458535e-4
GO:0072422 signal transduction involved in DNA damage checkpoint 9.460145e-4
GO:0023056 positive regulation of signaling 9.548398e-4
GO:0030335 positive regulation of cell migration 9.864941e-4
GO:0002637 regulation of immunoglobulin production 9.929170e-4
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 9.981988e-4
GO:0032252 secretory granule localization 1.014921e-3
GO:0001822 kidney development 1.066484e-3
GO:0050701 interleukin-1 secretion 1.088331e-3
GO:0045062 extrathymic T cell selection 1.088331e-3
GO:0071675 regulation of mononuclear cell migration 1.102414e-3
GO:0009265 2'-deoxyribonucleotide biosynthetic process 1.103331e-3
GO:0051387 negative regulation of nerve growth factor receptor signaling pathway 1.110229e-3
GO:0008535 respiratory chain complex IV assembly 1.110229e-3
GO:0051918 negative regulation of fibrinolysis 1.123381e-3
GO:0071773 cellular response to BMP stimulus 1.135334e-3
GO:0060429 epithelium development 1.150316e-3
GO:0002312 B cell activation involved in immune response 1.158477e-3
GO:0045663 positive regulation of myoblast differentiation 1.171131e-3
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1.186152e-3
GO:0003300 cardiac muscle hypertrophy 1.209050e-3
GO:0045058 T cell selection 1.250901e-3
GO:0044344 cellular response to fibroblast growth factor stimulus 1.267248e-3
GO:0010955 negative regulation of protein processing 1.269766e-3
GO:0035904 aorta development 1.273228e-3
GO:0060079 regulation of excitatory postsynaptic membrane potential 1.277084e-3
GO:0002762 negative regulation of myeloid leukocyte differentiation 1.317551e-3
GO:0003207 cardiac chamber formation 1.317551e-3
GO:0032612 interleukin-1 production 1.321950e-3
GO:0003279 cardiac septum development 1.326543e-3
GO:2000147 positive regulation of cell motility 1.326563e-3
GO:0003014 renal system process 1.334301e-3
GO:0035282 segmentation 1.341574e-3
GO:0032755 positive regulation of interleukin-6 production 1.355842e-3
GO:0070848 response to growth factor stimulus 1.358775e-3
GO:0006367 transcription initiation from RNA polymerase II promoter 1.360244e-3
GO:0050767 regulation of neurogenesis 1.366831e-3
GO:0006779 porphyrin-containing compound biosynthetic process 1.369102e-3
GO:0045577 regulation of B cell differentiation 1.398643e-3
GO:0006879 cellular iron ion homeostasis 1.398643e-3
GO:2000270 negative regulation of fibroblast apoptosis 1.407714e-3
GO:2000271 positive regulation of fibroblast apoptosis 1.407714e-3
GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 1.407714e-3
GO:0044345 stromal-epithelial cell signaling involved in prostate gland development 1.407714e-3
GO:0021570 rhombomere 4 development 1.407714e-3
GO:0006915 apoptosis 1.410997e-3
GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process 1.415827e-3
GO:0015939 pantothenate metabolic process 1.466671e-3
GO:0006911 phagocytosis, engulfment 1.509500e-3
GO:0051094 positive regulation of developmental process 1.525601e-3
GO:0016052 carbohydrate catabolic process 1.544205e-3
GO:0060044 negative regulation of cardiac muscle cell proliferation 1.589184e-3
GO:0015867 ATP transport 1.595165e-3
GO:0060043 regulation of cardiac muscle cell proliferation 1.596681e-3
GO:0015721 bile acid and bile salt transport 1.627653e-3
GO:0001932 regulation of protein phosphorylation 1.634259e-3
GO:0032103 positive regulation of response to external stimulus 1.639128e-3
GO:0010810 regulation of cell-substrate adhesion 1.656093e-3
GO:0043030 regulation of macrophage activation 1.673625e-3
GO:0048699 generation of neurons 1.678368e-3
GO:0046078 dUMP metabolic process 1.709829e-3
GO:0009223 pyrimidine deoxyribonucleotide catabolic process 1.709829e-3
GO:0051960 regulation of nervous system development 1.721818e-3
GO:0040011 locomotion 1.730089e-3
GO:0001757 somite specification 1.761615e-3
GO:0042147 retrograde transport, endosome to Golgi 1.764099e-3
GO:0009605 response to external stimulus 1.783331e-3
GO:0055024 regulation of cardiac muscle tissue development 1.813115e-3
GO:0021915 neural tube development 1.817821e-3
GO:0070293 renal absorption 1.839915e-3
GO:0002695 negative regulation of leukocyte activation 1.842778e-3
GO:0051883 killing of cells in other organism involved in symbiotic interaction 1.868783e-3
GO:0003357 noradrenergic neuron differentiation 1.868783e-3
GO:0030901 midbrain development 1.873212e-3
GO:0046640 regulation of alpha-beta T cell proliferation 1.880528e-3
GO:0046631 alpha-beta T cell activation 1.886801e-3
GO:0042136 neurotransmitter biosynthetic process 1.902748e-3
GO:2000648 positive regulation of stem cell proliferation 1.923738e-3
GO:0016202 regulation of striated muscle tissue development 1.927005e-3
GO:0030001 metal ion transport 1.941903e-3
GO:0046164 alcohol catabolic process 1.945060e-3
GO:0034695 response to prostaglandin E stimulus 1.945430e-3
GO:0090287 regulation of cellular response to growth factor stimulus 1.955496e-3
GO:0048608 reproductive structure development 1.979691e-3
GO:0015908 fatty acid transport 1.983391e-3
GO:0030889 negative regulation of B cell proliferation 1.986910e-3
GO:0070365 hepatocyte differentiation 1.989952e-3
GO:2000079 regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation 2.020242e-3
GO:0048634 regulation of muscle organ development 2.051460e-3
GO:0031640 killing of cells of other organism 2.059864e-3
GO:0060554 induction of necroptosis of activated-T cells 2.085925e-3
GO:0071842 cellular component organization at cellular level 2.088302e-3
GO:0050854 regulation of antigen receptor-mediated signaling pathway 2.110539e-3
GO:0006700 C21-steroid hormone biosynthetic process 2.127170e-3
GO:0044271 cellular nitrogen compound biosynthetic process 2.146925e-3
GO:0051186 cofactor metabolic process 2.153838e-3
GO:0002326 B cell lineage commitment 2.204957e-3
GO:0050777 negative regulation of immune response 2.215215e-3
GO:0031399 regulation of protein modification process 2.219095e-3
GO:0051893 regulation of focal adhesion assembly 2.238041e-3
GO:0072001 renal system development 2.239810e-3
GO:0048518 positive regulation of biological process 2.242759e-3
GO:0012501 programmed cell death 2.258539e-3
GO:0010758 regulation of macrophage chemotaxis 2.267261e-3
GO:0051584 regulation of dopamine uptake 2.280044e-3
GO:0002309 T cell proliferation involved in immune response 2.280044e-3
GO:0006302 double-strand break repair 2.365783e-3
GO:0060078 regulation of postsynaptic membrane potential 2.382920e-3
GO:0051917 regulation of fibrinolysis 2.387917e-3
GO:0001542 ovulation from ovarian follicle 2.395290e-3
GO:0070373 negative regulation of ERK1 and ERK2 cascade 2.413233e-3
GO:0061337 cardiac conduction 2.418585e-3
GO:0048468 cell development 2.426998e-3
GO:0006477 protein sulfation 2.427724e-3
GO:0034453 microtubule anchoring 2.433525e-3
GO:0010812 negative regulation of cell-substrate adhesion 2.451788e-3
GO:0003211 cardiac ventricle formation 2.466352e-3
GO:0051656 establishment of organelle localization 2.499111e-3
GO:0055062 phosphate ion homeostasis 2.508166e-3
GO:0045670 regulation of osteoclast differentiation 2.509975e-3
GO:0030890 positive regulation of B cell proliferation 2.526291e-3
GO:0001890 placenta development 2.534698e-3
GO:0060402 calcium ion transport into cytosol 2.553494e-3
GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2.562526e-3
GO:0035239 tube morphogenesis 2.564625e-3
GO:0022008 neurogenesis 2.597732e-3
GO:0044087 regulation of cellular component biogenesis 2.617390e-3
GO:2000791 negative regulation of mesenchymal cell proliferation involved in lung development 2.618628e-3
GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis 2.618628e-3
GO:0061141 lung ciliated cell differentiation 2.618628e-3
GO:0021740 principal sensory nucleus of trigeminal nerve development 2.618628e-3
GO:0010757 negative regulation of plasminogen activation 2.618628e-3
GO:0001910 regulation of leukocyte mediated cytotoxicity 2.657561e-3
GO:0043113 receptor clustering 2.695434e-3
GO:0048302 regulation of isotype switching to IgG isotypes 2.695736e-3
GO:0055075 potassium ion homeostasis 2.702338e-3
GO:0045992 negative regulation of embryonic development 2.736236e-3
GO:0035587 purinergic receptor signaling pathway 2.739945e-3
GO:0002360 T cell lineage commitment 2.746180e-3
GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 2.800484e-3
GO:0045329 carnitine biosynthetic process 2.814433e-3
GO:0055117 regulation of cardiac muscle contraction 2.830544e-3
GO:0008105 asymmetric protein localization 2.858939e-3
GO:0010755 regulation of plasminogen activation 2.864601e-3
GO:0034260 negative regulation of GTPase activity 2.864601e-3
GO:0006529 asparagine biosynthetic process 2.984711e-3
GO:0010647 positive regulation of cell communication 2.996751e-3
GO:0048385 regulation of retinoic acid receptor signaling pathway 2.998407e-3
GO:0015868 purine ribonucleotide transport 3.050952e-3
GO:0071363 cellular response to growth factor stimulus 3.076644e-3
GO:0051149 positive regulation of muscle cell differentiation 3.121174e-3
GO:0035136 forelimb morphogenesis 3.129750e-3
GO:0050860 negative regulation of T cell receptor signaling pathway 3.153913e-3
GO:0070861 regulation of protein exit from endoplasmic reticulum 3.153981e-3
GO:0071955 recycling endosome to Golgi transport 3.153981e-3
GO:0045356 positive regulation of interferon-alpha biosynthetic process 3.153981e-3
GO:0034499 late endosome to Golgi transport 3.153981e-3
GO:0007208 activation of phospholipase C activity by serotonin receptor signaling pathway 3.153981e-3
GO:0001964 startle response 3.169556e-3
GO:0015718 monocarboxylic acid transport 3.176448e-3
GO:0042573 retinoic acid metabolic process 3.223381e-3
GO:0097114 N-methyl-D-aspartate receptor clustering 3.232242e-3
GO:0097117 guanylate kinase-associated protein clustering 3.232242e-3
GO:0097112 gamma-aminobutyric acid receptor clustering 3.232242e-3
GO:0001915 negative regulation of T cell mediated cytotoxicity 3.256882e-3
GO:0031065 positive regulation of histone deacetylation 3.282362e-3
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 3.294919e-3
GO:0014009 glial cell proliferation 3.303199e-3
GO:0050671 positive regulation of lymphocyte proliferation 3.312176e-3
GO:0008340 determination of adult lifespan 3.363691e-3
GO:0006903 vesicle targeting 3.406681e-3
GO:0002526 acute inflammatory response 3.407095e-3
GO:0006376 mRNA splice site selection 3.447094e-3
GO:0008211 glucocorticoid metabolic process 3.447094e-3
GO:0035117 embryonic arm morphogenesis 3.457993e-3
GO:0051896 regulation of protein kinase B signaling cascade 3.475309e-3
GO:0001654 eye development 3.486956e-3
GO:0001655 urogenital system development 3.516776e-3
GO:0046826 negative regulation of protein export from nucleus 3.521320e-3
GO:0055021 regulation of cardiac muscle tissue growth 3.522777e-3
GO:0043576 regulation of respiratory gaseous exchange 3.527430e-3
GO:0060040 retinal bipolar neuron differentiation 3.555943e-3
GO:0070409 carbamoyl phosphate biosynthetic process 3.555943e-3
GO:0033625 positive regulation of integrin activation 3.555943e-3
GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway 3.555943e-3
GO:0060420 regulation of heart growth 3.682873e-3
GO:0071481 cellular response to X-ray 3.735505e-3
GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response 3.820867e-3
GO:0008406 gonad development 3.830394e-3
GO:0045590 negative regulation of regulatory T cell differentiation 3.845394e-3
GO:0044065 regulation of respiratory system process 3.942572e-3
GO:0014888 striated muscle adaptation 3.963798e-3
GO:0007220 Notch receptor processing 3.975524e-3
GO:0060706 cell differentiation involved in embryonic placenta development 3.979703e-3
GO:0002087 regulation of respiratory gaseous exchange by neurological system process 3.979703e-3
GO:0050866 negative regulation of cell activation 4.026450e-3
GO:0048806 genitalia development 4.035879e-3
GO:2000045 regulation of G1/S transition of mitotic cell cycle 4.037009e-3
GO:0045137 development of primary sexual characteristics 4.100514e-3
GO:0032946 positive regulation of mononuclear cell proliferation 4.167281e-3