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Novel motif:85

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name:motif85_TWNNGCSNA

Association to promoter expression in human samples
Summary:Significance of the correlation with CAGE expression, human
Analyst: Michiel de Hoon



link to source dataset

data



Association to promoter expression in mouse samples

Summary:Significance of the correlation with CAGE expression, mouse
Analyst: Michiel de Hoon



link to source dataset

data



GREAT analysis results for human

Summary:Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon



link to source dataset

data

GO IDGO Termp-value
GO:0006261 DNA-dependent DNA replication 3.550965e-10
GO:0042254 ribosome biogenesis 8.552938e-10
GO:0022616 DNA strand elongation 1.296524e-9
GO:0051320 S phase 7.059854e-9
GO:0006271 DNA strand elongation involved in DNA replication 1.034905e-8
GO:0000084 S phase of mitotic cell cycle 5.734235e-8
GO:0034470 ncRNA processing 9.643640e-8
GO:0060236 regulation of mitotic spindle organization 1.039478e-7
GO:0016072 rRNA metabolic process 1.426643e-7
GO:0030488 tRNA methylation 1.628215e-7
GO:0030683 evasion by virus of host immune response 2.647720e-7
GO:0006406 mRNA export from nucleus 2.971740e-7
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 3.513720e-7
GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 3.513720e-7
GO:0006396 RNA processing 3.668932e-7
GO:0034660 ncRNA metabolic process 3.671607e-7
GO:0022613 ribonucleoprotein complex biogenesis 5.036346e-7
GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions 5.087186e-7
GO:0014005 microglia development 6.398914e-7
GO:0001510 RNA methylation 8.342221e-7
GO:0032201 telomere maintenance via semi-conservative replication 8.418763e-7
GO:0006379 mRNA cleavage 1.412704e-6
GO:0080009 mRNA methylation 1.762152e-6
GO:0042747 circadian sleep/wake cycle, REM sleep 1.762152e-6
GO:0090305 nucleic acid phosphodiester bond hydrolysis 1.763897e-6
GO:0009451 RNA modification 1.827237e-6
GO:0051083 'de novo' cotranslational protein folding 1.869873e-6
GO:0071843 cellular component biogenesis at cellular level 2.727780e-6
GO:0000730 DNA recombinase assembly 2.850110e-6
GO:0046939 nucleotide phosphorylation 2.863039e-6
GO:0006281 DNA repair 3.263741e-6
GO:0006405 RNA export from nucleus 3.559175e-6
GO:0015693 magnesium ion transport 3.647414e-6
GO:0000722 telomere maintenance via recombination 4.168695e-6
GO:0033566 gamma-tubulin complex localization 4.394076e-6
GO:0006844 acyl carnitine transport 4.546906e-6
GO:0032074 negative regulation of nuclease activity 4.724462e-6
GO:0016071 mRNA metabolic process 5.386627e-6
GO:0006297 nucleotide-excision repair, DNA gap filling 5.880219e-6
GO:0006364 rRNA processing 6.489550e-6
GO:0006370 mRNA capping 7.631368e-6
GO:0006289 nucleotide-excision repair 7.649048e-6
GO:0009386 translational attenuation 7.993346e-6
GO:0061316 canonical Wnt receptor signaling pathway involved in heart development 8.356064e-6
GO:0060816 random inactivation of X chromosome 1.115087e-5
GO:0000724 double-strand break repair via homologous recombination 1.279319e-5
GO:0008216 spermidine metabolic process 1.380568e-5
GO:0048075 positive regulation of eye pigmentation 1.380568e-5
GO:0006458 'de novo' protein folding 1.515750e-5
GO:0000076 DNA replication checkpoint 1.569126e-5
GO:0000725 recombinational repair 1.621282e-5
GO:0009452 RNA capping 1.948986e-5
GO:0051028 mRNA transport 2.046531e-5
GO:0000723 telomere maintenance 2.350429e-5
GO:0006312 mitotic recombination 2.474173e-5
GO:0000080 G1 phase of mitotic cell cycle 2.524663e-5
GO:0071156 regulation of cell cycle arrest 2.653423e-5
GO:0032312 regulation of ARF GTPase activity 2.724061e-5
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 2.789718e-5
GO:0000917 barrier septum formation 2.977390e-5
GO:0007127 meiosis I 3.029497e-5
GO:0050747 positive regulation of lipoprotein metabolic process 3.059686e-5
GO:0090162 establishment of epithelial cell polarity 3.083818e-5
GO:0043456 regulation of pentose-phosphate shunt 3.241195e-5
GO:0042270 protection from natural killer cell mediated cytotoxicity 3.399119e-5
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 3.547796e-5
GO:0000389 nuclear mRNA 3'-splice site recognition 3.686575e-5
GO:0010498 proteasomal protein catabolic process 5.435900e-5
GO:0044265 cellular macromolecule catabolic process 5.616653e-5
GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis 5.617563e-5
GO:0033342 negative regulation of collagen binding 5.639108e-5
GO:0021943 formation of radial glial scaffolds 5.899828e-5
GO:0034509 centromeric core chromatin assembly 5.910838e-5
GO:0000216 M/G1 transition of mitotic cell cycle 5.962547e-5
GO:0050658 RNA transport 5.983135e-5
GO:0048073 regulation of eye pigmentation 6.055706e-5
GO:0001830 trophectodermal cell fate commitment 6.102608e-5
GO:0030322 stabilization of membrane potential 6.102608e-5
GO:0006310 DNA recombination 6.423274e-5
GO:0006284 base-excision repair 6.659492e-5
GO:0030206 chondroitin sulfate biosynthetic process 6.759910e-5
GO:0042771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 7.183214e-5
GO:0031118 rRNA pseudouridine synthesis 7.327834e-5
GO:0060019 radial glial cell differentiation 7.679679e-5
GO:0051546 keratinocyte migration 8.053283e-5
GO:0010833 telomere maintenance via telomere lengthening 8.123722e-5
GO:0016032 viral reproduction 8.127948e-5
GO:0016180 snRNA processing 8.179355e-5
GO:0070192 chromosome organization involved in meiosis 8.426745e-5
GO:0006260 DNA replication 8.800220e-5
GO:0034241 positive regulation of macrophage fusion 8.868271e-5
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.868271e-5
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.868271e-5
GO:0006534 cysteine metabolic process 9.050574e-5
GO:0007614 short-term memory 9.399296e-5
GO:0006403 RNA localization 9.734291e-5
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.939199e-5
GO:0032790 ribosome disassembly 9.939199e-5
GO:0071816 tail-anchored membrane protein insertion into ER membrane 1.047383e-4
GO:0000075 cell cycle checkpoint 1.079993e-4
GO:0035659 Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells 1.100758e-4
GO:0014719 satellite cell activation 1.100758e-4
GO:0032200 telomere organization 1.192962e-4
GO:0003016 respiratory system process 1.216013e-4
GO:0006414 translational elongation 1.265501e-4
GO:0045008 depyrimidination 1.417819e-4
GO:0006308 DNA catabolic process 1.458295e-4
GO:0042770 signal transduction in response to DNA damage 1.535954e-4
GO:0030208 dermatan sulfate biosynthetic process 1.563891e-4
GO:0065002 intracellular protein transmembrane transport 1.655549e-4
GO:0070086 ubiquitin-dependent endocytosis 1.938250e-4
GO:0016073 snRNA metabolic process 2.324050e-4
GO:0031497 chromatin assembly 2.436643e-4
GO:0060066 oviduct development 2.440898e-4
GO:0051106 positive regulation of DNA ligation 2.476979e-4
GO:0097037 heme export 2.476979e-4
GO:0019079 viral genome replication 2.508147e-4
GO:2000016 negative regulation of determination of dorsal identity 2.728703e-4
GO:0008295 spermidine biosynthetic process 2.728703e-4
GO:0030330 DNA damage response, signal transduction by p53 class mediator 2.822498e-4
GO:0032863 activation of Rac GTPase activity 2.883296e-4
GO:0016556 mRNA modification 2.975629e-4
GO:0018345 protein palmitoylation 3.015577e-4
GO:0030903 notochord development 3.128795e-4
GO:0031125 rRNA 3'-end processing 3.133214e-4
GO:0030163 protein catabolic process 3.182784e-4
GO:0071028 nuclear mRNA surveillance 3.257369e-4
GO:0030421 defecation 3.257369e-4
GO:0006777 Mo-molybdopterin cofactor biosynthetic process 3.282174e-4
GO:0021932 hindbrain radial glia guided cell migration 3.348320e-4
GO:0006283 transcription-coupled nucleotide-excision repair 3.399086e-4
GO:0051318 G1 phase 3.466651e-4
GO:0007128 meiotic prophase I 3.646257e-4
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3.817109e-4
GO:0006259 DNA metabolic process 4.051532e-4
GO:0019083 viral transcription 4.148024e-4
GO:0003308 negative regulation of Wnt receptor signaling pathway involved in heart development 4.387442e-4
GO:0060992 response to fungicide 4.487074e-4
GO:0000077 DNA damage checkpoint 4.885301e-4
GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway 5.029474e-4
GO:0060035 notochord cell development 5.092390e-4
GO:0031570 DNA integrity checkpoint 5.132522e-4
GO:0090224 regulation of spindle organization 5.153404e-4
GO:0030204 chondroitin sulfate metabolic process 5.167948e-4
GO:0000236 mitotic prometaphase 5.183946e-4
GO:0035136 forelimb morphogenesis 5.250065e-4
GO:0035115 embryonic forelimb morphogenesis 5.312530e-4
GO:0021681 cerebellar granular layer development 5.687087e-4
GO:0031848 protection from non-homologous end joining at telomere 5.697724e-4
GO:0071158 positive regulation of cell cycle arrest 5.805102e-4
GO:0006974 response to DNA damage stimulus 5.852552e-4
GO:0051531 NFAT protein import into nucleus 5.912740e-4
GO:0010933 positive regulation of macrophage tolerance induction 6.092375e-4
GO:0006051 N-acetylmannosamine metabolic process 6.092375e-4
GO:0003222 ventricular trabecular myocardium morphogenesis 6.268427e-4
GO:0045063 T-helper 1 cell differentiation 6.280544e-4
GO:0046782 regulation of viral transcription 6.342998e-4
GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 6.428957e-4
GO:0046500 S-adenosylmethionine metabolic process 6.651685e-4
GO:0019058 viral infectious cycle 6.724453e-4
GO:0043921 modulation by host of viral transcription 6.937527e-4
GO:0040032 post-embryonic body morphogenesis 7.252564e-4
GO:0051225 spindle assembly 7.386022e-4
GO:0006415 translational termination 7.472632e-4
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 7.605671e-4
GO:0009223 pyrimidine deoxyribonucleotide catabolic process 8.150495e-4
GO:0043632 modification-dependent macromolecule catabolic process 8.337181e-4
GO:0032780 negative regulation of ATPase activity 8.350504e-4
GO:0043628 ncRNA 3'-end processing 8.592153e-4
GO:0043181 vacuolar sequestering 8.856608e-4
GO:0035621 ER to Golgi ceramide transport 8.856608e-4
GO:0000023 maltose metabolic process 8.856608e-4
GO:0005985 sucrose metabolic process 8.856608e-4
GO:0061084 negative regulation of protein refolding 8.954872e-4
GO:0033590 response to cobalamin 9.242272e-4
GO:0006117 acetaldehyde metabolic process 9.242272e-4
GO:0050434 positive regulation of viral transcription 9.632254e-4
GO:0007129 synapsis 9.698713e-4
GO:0060741 prostate gland stromal morphogenesis 9.777323e-4
GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 1.002190e-3
GO:0031860 telomeric 3' overhang formation 1.081775e-3
GO:0018192 enzyme active site formation via L-cysteine persulfide 1.081775e-3
GO:0009446 putrescine biosynthetic process 1.081775e-3
GO:0015761 mannose transport 1.081775e-3
GO:0000022 mitotic spindle elongation 1.108508e-3
GO:0048102 autophagic cell death 1.139979e-3
GO:0003307 regulation of Wnt receptor signaling pathway involved in heart development 1.143493e-3
GO:0071638 negative regulation of monocyte chemotactic protein-1 production 1.239873e-3
GO:0035732 nitric oxide storage 1.239873e-3
GO:0031468 nuclear envelope reassembly 1.239873e-3
GO:0035726 common myeloid progenitor cell proliferation 1.239873e-3
GO:0035083 cilium axoneme assembly 1.274107e-3
GO:0051324 prophase 1.282647e-3
GO:0010520 regulation of reciprocal meiotic recombination 1.319674e-3
GO:0032682 negative regulation of chemokine production 1.319674e-3
GO:0071394 cellular response to testosterone stimulus 1.353381e-3
GO:0019448 L-cysteine catabolic process 1.353381e-3
GO:0006313 transposition, DNA-mediated 1.353381e-3
GO:0008334 histone mRNA metabolic process 1.362330e-3
GO:0019941 modification-dependent protein catabolic process 1.370185e-3
GO:0009057 macromolecule catabolic process 1.378073e-3
GO:0071726 cellular response to diacyl bacterial lipopeptide 1.409522e-3
GO:0042496 detection of diacyl bacterial lipopeptide 1.409522e-3
GO:0043923 positive regulation by host of viral transcription 1.454346e-3
GO:0070863 positive regulation of protein exit from endoplasmic reticulum 1.464701e-3
GO:0021861 forebrain radial glial cell differentiation 1.493498e-3
GO:0006511 ubiquitin-dependent protein catabolic process 1.503328e-3
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1.509183e-3
GO:0043105 negative regulation of GTP cyclohydrolase I activity 1.517601e-3
GO:0007007 inner mitochondrial membrane organization 1.534539e-3
GO:0046590 embryonic leg morphogenesis 1.543650e-3
GO:0072404 signal transduction involved in G1/S transition checkpoint 1.557261e-3
GO:0071025 RNA surveillance 1.560200e-3
GO:0014028 notochord formation 1.560200e-3
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1.682418e-3
GO:0070060 'de novo' actin filament nucleation 1.682418e-3
GO:0006400 tRNA modification 1.763553e-3
GO:0051084 'de novo' posttranslational protein folding 1.799520e-3
GO:0072422 signal transduction involved in DNA damage checkpoint 1.820656e-3
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 1.828839e-3
GO:0014908 myotube differentiation involved in skeletal muscle regeneration 1.838147e-3
GO:0072395 signal transduction involved in cell cycle checkpoint 1.873147e-3
GO:0006333 chromatin assembly or disassembly 1.879632e-3
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 1.891172e-3
GO:0000244 assembly of spliceosomal tri-snRNP 1.903628e-3
GO:0001696 gastric acid secretion 1.907603e-3
GO:0000718 nucleotide-excision repair, DNA damage removal 1.926427e-3
GO:0034976 response to endoplasmic reticulum stress 1.970556e-3
GO:0060381 positive regulation of single-stranded telomeric DNA binding 2.047381e-3
GO:0006244 pyrimidine nucleotide catabolic process 2.101729e-3
GO:0065004 protein-DNA complex assembly 2.124569e-3
GO:0051603 proteolysis involved in cellular protein catabolic process 2.135996e-3
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 2.139618e-3
GO:0050654 chondroitin sulfate proteoglycan metabolic process 2.169881e-3
GO:0007212 dopamine receptor signaling pathway 2.206506e-3
GO:0090244 Wnt receptor signaling pathway involved in somitogenesis 2.219567e-3
GO:0015931 nucleobase-containing compound transport 2.229523e-3
GO:0071727 cellular response to triacyl bacterial lipopeptide 2.311261e-3
GO:0042495 detection of triacyl bacterial lipopeptide 2.311261e-3
GO:0006482 protein demethylation 2.468957e-3
GO:0046967 cytosol to ER transport 2.477792e-3
GO:0070307 lens fiber cell development 2.501693e-3
GO:0019532 oxalate transport 2.537046e-3
GO:0071895 odontoblast differentiation 2.537046e-3
GO:0044257 cellular protein catabolic process 2.667194e-3
GO:0006285 base-excision repair, AP site formation 2.779952e-3
GO:0035986 senescence-associated heterochromatin focus formation 2.789342e-3
GO:2000774 positive regulation of cellular senescence 2.789342e-3
GO:0006393 termination of mitochondrial transcription 2.855830e-3
GO:0048291 isotype switching to IgG isotypes 2.855830e-3
GO:0002842 positive regulation of T cell mediated immune response to tumor cell 2.855830e-3
GO:0002368 B cell cytokine production 2.855830e-3
GO:0019346 transsulfuration 2.874010e-3
GO:0043418 homocysteine catabolic process 2.874010e-3
GO:0006535 cysteine biosynthetic process from serine 2.874010e-3
GO:0019343 cysteine biosynthetic process via cystathionine 2.874010e-3
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 2.986000e-3
GO:0002031 G-protein coupled receptor internalization 2.986000e-3
GO:0070340 detection of bacterial lipopeptide 3.040867e-3
GO:0045005 maintenance of fidelity involved in DNA-dependent DNA replication 3.115781e-3
GO:0061324 canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation 3.117391e-3
GO:0034629 cellular protein complex localization 3.143342e-3
GO:0071824 protein-DNA complex subunit organization 3.179491e-3
GO:0006353 transcription termination, DNA-dependent 3.184742e-3
GO:0051256 spindle midzone assembly involved in mitosis 3.294844e-3
GO:0003306 Wnt receptor signaling pathway involved in heart development 3.302702e-3
GO:0032741 positive regulation of interleukin-18 production 3.320699e-3
GO:0046931 pore complex assembly 3.348535e-3
GO:0072331 signal transduction by p53 class mediator 3.413726e-3
GO:0034728 nucleosome organization 3.468582e-3
GO:0046323 glucose import 3.493624e-3
GO:0032049 cardiolipin biosynthetic process 3.529553e-3
GO:0051414 response to cortisol stimulus 3.549117e-3
GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration 3.620374e-3
GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis 3.643195e-3
GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 3.643195e-3
GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure 3.643195e-3
GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis 3.643195e-3
GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis 3.643195e-3
GO:0009231 riboflavin biosynthetic process 3.643195e-3
GO:0061310 canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development 3.643195e-3
GO:2000055 positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 3.643195e-3
GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis 3.643195e-3
GO:0045655 regulation of monocyte differentiation 3.644229e-3
GO:0015868 purine ribonucleotide transport 3.690269e-3
GO:0070059 apoptosis in response to endoplasmic reticulum stress 3.730196e-3
GO:0051168 nuclear export 3.769048e-3
GO:0034623 cellular macromolecular complex disassembly 3.889931e-3
GO:0000966 RNA 5'-end processing 3.903420e-3
GO:0016233 telomere capping 3.940835e-3
GO:2000015 regulation of determination of dorsal identity 4.058339e-3
GO:0031133 regulation of axon diameter 4.058339e-3
GO:0031297 replication fork processing 4.065107e-3
GO:0006334 nucleosome assembly 4.134622e-3
GO:0018184 protein polyamination 4.159896e-3
GO:0002033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure 4.159896e-3
GO:0048715 negative regulation of oligodendrocyte differentiation 4.272029e-3
GO:0030223 neutrophil differentiation 4.283043e-3
GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 4.355614e-3
GO:0009219 pyrimidine deoxyribonucleotide metabolic process 4.379655e-3
GO:0008033 tRNA processing 4.419421e-3
GO:0031629 synaptic vesicle fusion to presynaptic membrane 4.434585e-3
GO:0031397 negative regulation of protein ubiquitination 4.503439e-3
GO:0070537 histone H2A K63-linked deubiquitination 4.540833e-3
GO:2000786 positive regulation of autophagic vacuole assembly 4.540833e-3
GO:0090245 axis elongation involved in somitogenesis 4.540833e-3
GO:0021874 Wnt receptor signaling pathway involved in forebrain neuroblast division 4.540833e-3
GO:0070358 actin polymerization-dependent cell motility 4.540833e-3
GO:0010891 negative regulation of sequestering of triglyceride 4.605736e-3
GO:0032392 DNA geometric change 4.624694e-3
GO:0060282 positive regulation of oocyte development 4.647972e-3
GO:0090304 nucleic acid metabolic process 4.677712e-3
GO:0048320 axial mesoderm formation 4.831137e-3
GO:0050746 regulation of lipoprotein metabolic process 4.843696e-3
GO:0046755 non-lytic virus budding 4.868105e-3
GO:0016577 histone demethylation 5.160751e-3
GO:0006983 ER overload response 5.432164e-3
GO:0048524 positive regulation of viral reproduction 5.557638e-3
GO:0044335 canonical Wnt receptor signaling pathway involved in neural crest cell differentiation 5.576053e-3
GO:0051292 nuclear pore complex assembly 5.576053e-3
GO:0046341 CDP-diacylglycerol metabolic process 5.576053e-3
GO:0043316 cytotoxic T cell degranulation 5.576053e-3
GO:0034314 Arp2/3 complex-mediated actin nucleation 5.576053e-3
GO:0042727 flavin-containing compound biosynthetic process 5.576053e-3
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 5.638376e-3
GO:0021893 cerebral cortex GABAergic interneuron fate commitment 5.656881e-3
GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 5.656881e-3
GO:0070602 regulation of centromeric sister chromatid cohesion 5.711232e-3
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 5.736448e-3
GO:0046604 positive regulation of mitotic centrosome separation 5.771255e-3
GO:0046501 protoporphyrinogen IX metabolic process 6.169219e-3
GO:0051851 modification by host of symbiont morphology or physiology 6.198928e-3
GO:0051890 regulation of cardioblast differentiation 6.304442e-3
GO:2000772 regulation of cellular senescence 6.323652e-3
GO:0000387 spliceosomal snRNP assembly 6.324005e-3
GO:2000053 regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification 6.339987e-3
GO:0032930 positive regulation of superoxide anion generation 6.339987e-3
GO:0021794 thalamus development 6.343772e-3
GO:0060743 epithelial cell maturation involved in prostate gland development 6.343772e-3
GO:0090343 positive regulation of cell aging 6.347755e-3
GO:0006488 dolichol-linked oligosaccharide biosynthetic process 6.492932e-3
GO:0032988 ribonucleoprotein complex disassembly 6.521343e-3
GO:0097029 mature dendritic cell differentiation 6.531568e-3
GO:0071872 cellular response to epinephrine stimulus 6.531568e-3
GO:0009394 2'-deoxyribonucleotide metabolic process 6.572708e-3
GO:0021879 forebrain neuron differentiation 6.605352e-3
GO:0031442 positive regulation of mRNA 3'-end processing 6.721665e-3
GO:0002678 positive regulation of chronic inflammatory response 6.721665e-3
GO:0044342 type B pancreatic cell proliferation 6.757506e-3
GO:0015789 UDP-N-acetylgalactosamine transport 6.757506e-3
GO:0010918 positive regulation of mitochondrial membrane potential 6.757506e-3
GO:0015787 UDP-glucuronic acid transport 6.757506e-3
GO:0010889 regulation of sequestering of triglyceride 6.758532e-3
GO:0097039 protein linear polyubiquitination 6.912038e-3
GO:0072332 signal transduction by p53 class mediator resulting in induction of apoptosis 6.920213e-3
GO:0046498 S-adenosylhomocysteine metabolic process 6.944214e-3
GO:0033148 positive regulation of estrogen receptor signaling pathway 6.944214e-3
GO:0016137 glycoside metabolic process 7.013423e-3
GO:0000380 alternative nuclear mRNA splicing, via spliceosome 7.013423e-3
GO:0022415 viral reproductive process 7.043218e-3
GO:0035137 hindlimb morphogenesis 7.085521e-3
GO:0032984 macromolecular complex disassembly 7.118100e-3
GO:0044340 canonical Wnt receptor signaling pathway involved in regulation of cell proliferation 7.172007e-3
GO:0006369 termination of RNA polymerase II transcription 7.210191e-3
GO:0051444 negative regulation of ubiquitin-protein ligase activity 7.381837e-3
GO:0034445 negative regulation of plasma lipoprotein particle oxidation 7.496734e-3
GO:0070159 mitochondrial threonyl-tRNA aminoacylation 7.707012e-3
GO:2000251 positive regulation of actin cytoskeleton reorganization 7.717459e-3
GO:0045065 cytotoxic T cell differentiation 7.717459e-3
GO:0006734 NADH metabolic process 7.841579e-3
GO:0021773 striatal medium spiny neuron differentiation 7.869493e-3
GO:0019060 intracellular transport of viral proteins in host cell 7.869493e-3
GO:0070193 synaptonemal complex organization 7.918339e-3
GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development 8.110838e-3
GO:0051712 positive regulation of killing of cells of other organism 8.110838e-3
GO:0090342 regulation of cell aging 8.151170e-3
GO:0021872 forebrain generation of neurons 8.171087e-3
GO:0090307 spindle assembly involved in mitosis 8.534136e-3
GO:0001514 selenocysteine incorporation 8.534136e-3
GO:0043922 negative regulation by host of viral transcription 8.547295e-3
GO:0016241 regulation of macroautophagy 8.556829e-3
GO:0010266 response to vitamin B1 8.639642e-3
GO:0031123 RNA 3'-end processing 8.639845e-3
GO:0014038 regulation of Schwann cell differentiation 8.776365e-3
GO:0070389 chaperone cofactor-dependent protein refolding 8.884673e-3
GO:0006613 cotranslational protein targeting to membrane 8.976325e-3
GO:0042093 T-helper cell differentiation 9.229442e-3
GO:0046069 cGMP catabolic process 9.353486e-3
GO:0045039 protein import into mitochondrial inner membrane 9.481826e-3
GO:0044088 regulation of vacuole organization 9.591088e-3
GO:0043624 cellular protein complex disassembly 9.740555e-3
GO:0060281 regulation of oocyte development 9.769915e-3
GO:0006311 meiotic gene conversion 9.980796e-3
GO:0010999 regulation of eIF2 alpha phosphorylation by heme 9.980796e-3
GO:0045128 negative regulation of reciprocal meiotic recombination 9.980796e-3
GO:0009589 detection of UV 9.980796e-3
GO:0046329 negative regulation of JNK cascade 1.009120e-2
GO:0021707 cerebellar granule cell differentiation 1.029569e-2
GO:0010172 embryonic body morphogenesis 1.029569e-2
GO:0090381 regulation of heart induction 1.047987e-2
GO:0006670 sphingosine metabolic process 1.097654e-2
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 1.097893e-2
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.116569e-2
GO:0051301 cell division 1.120277e-2
GO:0042726 flavin-containing compound metabolic process 1.125781e-2
GO:0034048 negative regulation of protein phosphatase type 2A activity 1.125781e-2
GO:0000375 RNA splicing, via transesterification reactions 1.145348e-2
GO:0043171 peptide catabolic process 1.161502e-2
GO:0072361 regulation of glycolysis by regulation of transcription from RNA polymerase II promoter 1.162048e-2
GO:0060431 primary lung bud formation 1.162048e-2
GO:0014040 positive regulation of Schwann cell differentiation 1.162048e-2
GO:0031440 regulation of mRNA 3'-end processing 1.182978e-2
GO:0032536 regulation of cell projection size 1.185162e-2
GO:0061153 trachea gland development 1.192349e-2
GO:0048103 somatic stem cell division 1.225592e-2
GO:0007051 spindle organization 1.230287e-2
GO:0048280 vesicle fusion with Golgi apparatus 1.234911e-2
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 1.251475e-2
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1.259939e-2
GO:0031627 telomeric loop formation 1.260307e-2
GO:0071279 cellular response to cobalt ion 1.260307e-2
GO:0010637 negative regulation of mitochondrial fusion 1.260307e-2
GO:0006397 mRNA processing 1.263037e-2
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.271607e-2
GO:0060631 regulation of meiosis I 1.277999e-2
GO:0060301 positive regulation of cytokine activity 1.277999e-2
GO:0007130 synaptonemal complex assembly 1.305815e-2
GO:0045656 negative regulation of monocyte differentiation 1.309989e-2
GO:0008612 peptidyl-lysine modification to hypusine 1.314376e-2
GO:0000096 sulfur amino acid metabolic process 1.327624e-2
GO:0002293 alpha-beta T cell differentiation involved in immune response 1.330657e-2
GO:0046434 organophosphate catabolic process 1.342886e-2
GO:0008053 mitochondrial fusion 1.365636e-2
GO:0032928 regulation of superoxide anion generation 1.382823e-2
GO:0015910 peroxisomal long-chain fatty acid import 1.383054e-2
GO:0000492 box C/D snoRNP assembly 1.383054e-2
GO:0042274 ribosomal small subunit biogenesis 1.386608e-2
GO:0001732 formation of translation initiation complex 1.401817e-2
GO:0006302 double-strand break repair 1.416252e-2
GO:0071103 DNA conformation change 1.443791e-2
GO:0032543 mitochondrial translation 1.448763e-2
GO:0030262 apoptotic nuclear change 1.453405e-2
GO:0021542 dentate gyrus development 1.455672e-2
GO:2000077 negative regulation of type B pancreatic cell development 1.512315e-2
GO:0060070 canonical Wnt receptor signaling pathway 1.515719e-2
GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter 1.542686e-2
GO:0072363 regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter 1.542686e-2
GO:0060385 axonogenesis involved in innervation 1.558143e-2
GO:0046607 positive regulation of centrosome cycle 1.558143e-2
GO:0032042 mitochondrial DNA metabolic process 1.656416e-2
GO:0048262 determination of dorsal/ventral asymmetry 1.672762e-2
GO:0043457 regulation of cellular respiration 1.672762e-2
GO:0021535 cell migration in hindbrain 1.697233e-2
GO:0008634 negative regulation of survival gene product expression 1.697233e-2
GO:0033136 serine phosphorylation of STAT3 protein 1.714150e-2
GO:0006598 polyamine catabolic process 1.714150e-2
GO:0032613 interleukin-10 production 1.714150e-2
GO:2000602 regulation of interphase of mitotic cell cycle 1.716858e-2
GO:0016081 synaptic vesicle docking involved in exocytosis 1.725143e-2
GO:0070814 hydrogen sulfide biosynthetic process 1.733277e-2
GO:0046853 inositol or phosphatidylinositol phosphorylation 1.733277e-2
GO:0035110 leg morphogenesis 1.773802e-2
GO:0043241 protein complex disassembly 1.780815e-2
GO:0020028 hemoglobin import 1.783211e-2
GO:0070972 protein localization in endoplasmic reticulum 1.790089e-2
GO:0000279 M phase 1.797489e-2
GO:0045931 positive regulation of mitotic cell cycle 1.805295e-2
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process 1.822897e-2
GO:0070979 protein K11-linked ubiquitination 1.841574e-2
GO:0032897 negative regulation of viral transcription 1.887209e-2
GO:0097107 postsynaptic density assembly 1.892086e-2
GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 1.892086e-2
GO:0043990 histone H2A-S1 phosphorylation 1.892086e-2
GO:0034725 DNA replication-dependent nucleosome disassembly 1.892086e-2
GO:0033314 mitotic cell cycle DNA replication checkpoint 1.892086e-2
GO:0006862 nucleotide transport 1.903308e-2
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.920869e-2
GO:0043403 skeletal muscle tissue regeneration 1.946365e-2
GO:0021877 forebrain neuron fate commitment 1.964237e-2
GO:0043508 negative regulation of JUN kinase activity 1.970286e-2
GO:0060479 lung cell differentiation 1.974713e-2
GO:0071168 protein localization to chromatin 1.980564e-2
GO:0000398 nuclear mRNA splicing, via spliceosome 2.006208e-2
GO:0044272 sulfur compound biosynthetic process 2.018425e-2
GO:0050983 deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase 2.050112e-2
GO:0070309 lens fiber cell morphogenesis 2.050806e-2
GO:0006108 malate metabolic process 2.050806e-2
GO:0032661 regulation of interleukin-18 production 2.050806e-2
GO:0033145 positive regulation of steroid hormone receptor signaling pathway 2.051031e-2
GO:0051297 centrosome organization 2.059149e-2
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2.073494e-2
GO:0016476 regulation of embryonic cell shape 2.093849e-2
GO:0003218 cardiac left ventricle formation 2.093849e-2
GO:0001842 neural fold formation 2.093849e-2
GO:0032481 positive regulation of type I interferon production 2.133639e-2
GO:0031507 heterochromatin formation 2.137616e-2
GO:0009886 post-embryonic morphogenesis 2.209577e-2
GO:0050684 regulation of mRNA processing 2.214500e-2
GO:0002200 somatic diversification of immune receptors 2.222298e-2
GO:0071864 positive regulation of cell proliferation in bone marrow 2.290031e-2


GREAT analysis results for mouse
Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.
Analyst: Michiel de Hoon

link to source dataset

data

GO IDGO Termp-value
GO:0006396 RNA processing 4.180959e-15
GO:0016071 mRNA metabolic process 1.728639e-13
GO:0060837 blood vessel endothelial cell differentiation 4.079679e-10
GO:0046069 cGMP catabolic process 4.124586e-10
GO:0006397 mRNA processing 6.920127e-10
GO:0021528 commissural neuron differentiation in spinal cord 9.343775e-9
GO:0008616 queuosine biosynthetic process 2.054624e-8
GO:0071157 negative regulation of cell cycle arrest 2.270189e-8
GO:0010467 gene expression 4.163725e-8
GO:0046666 retinal cell programmed cell death 7.142366e-8
GO:0055119 relaxation of cardiac muscle 1.060738e-7
GO:0008380 RNA splicing 1.095034e-7
GO:0030644 cellular chloride ion homeostasis 1.095986e-7
GO:0090304 nucleic acid metabolic process 1.252862e-7
GO:0018293 protein-FAD linkage 2.414679e-7
GO:0006121 mitochondrial electron transport, succinate to ubiquinone 2.414679e-7
GO:0030320 cellular monovalent inorganic anion homeostasis 3.602553e-7
GO:0048050 post-embryonic eye morphogenesis 4.617090e-7
GO:0060236 regulation of mitotic spindle organization 6.274448e-7
GO:0016070 RNA metabolic process 6.582558e-7
GO:0060282 positive regulation of oocyte development 7.819163e-7
GO:0060281 regulation of oocyte development 7.819163e-7
GO:0008617 guanosine metabolic process 9.410148e-7
GO:0035234 germ cell programmed cell death 1.006019e-6
GO:0055118 negative regulation of cardiac muscle contraction 1.285188e-6
GO:0010564 regulation of cell cycle process 1.394409e-6
GO:0044260 cellular macromolecule metabolic process 1.461096e-6
GO:0010623 developmental programmed cell death 1.547616e-6
GO:0007049 cell cycle 1.636352e-6
GO:0046839 phospholipid dephosphorylation 2.632444e-6
GO:0009299 mRNA transcription 3.516953e-6
GO:0010948 negative regulation of cell cycle process 3.580166e-6
GO:0033088 negative regulation of immature T cell proliferation in thymus 3.899519e-6
GO:0015986 ATP synthesis coupled proton transport 4.065753e-6
GO:0010735 positive regulation of transcription via serum response element binding 5.174571e-6
GO:0048627 myoblast development 5.540810e-6
GO:2000016 negative regulation of determination of dorsal identity 6.790688e-6
GO:0010891 negative regulation of sequestering of triglyceride 7.229182e-6
GO:0046856 phosphatidylinositol dephosphorylation 7.229182e-6
GO:0060928 atrioventricular node cell development 1.014908e-5
GO:0060929 atrioventricular node cell fate commitment 1.014908e-5
GO:0003342 proepicardium development 1.014908e-5
GO:0003168 cardiac Purkinje fiber cell differentiation 1.014908e-5
GO:0006780 uroporphyrinogen III biosynthetic process 1.014908e-5
GO:0035584 calcium-mediated signaling using intracellular calcium source 1.051069e-5
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway 1.053527e-5
GO:0007088 regulation of mitosis 1.086273e-5
GO:0006983 ER overload response 1.297211e-5
GO:0018195 peptidyl-arginine modification 1.304953e-5
GO:0007031 peroxisome organization 1.316285e-5
GO:0016557 peroxisome membrane biogenesis 1.323469e-5
GO:0018216 peptidyl-arginine methylation 1.369305e-5
GO:0034470 ncRNA processing 1.449589e-5
GO:0010765 positive regulation of sodium ion transport 1.686342e-5
GO:0007032 endosome organization 1.704315e-5
GO:0000083 regulation of transcription involved in G1/S phase of mitotic cell cycle 1.961163e-5
GO:0042789 mRNA transcription from RNA polymerase II promoter 2.037795e-5
GO:0002368 B cell cytokine production 2.138235e-5
GO:0048291 isotype switching to IgG isotypes 2.138235e-5
GO:0002678 positive regulation of chronic inflammatory response 2.192623e-5
GO:0071340 skeletal muscle nicotinic acetylcholine receptor clustering 2.196546e-5
GO:0045841 negative regulation of mitotic metaphase/anaphase transition 2.209276e-5
GO:0046068 cGMP metabolic process 2.728823e-5
GO:0051586 positive regulation of dopamine uptake 2.815995e-5
GO:0042178 xenobiotic catabolic process 3.061594e-5
GO:0010889 regulation of sequestering of triglyceride 3.104297e-5
GO:0034660 ncRNA metabolic process 3.360247e-5
GO:0048668 collateral sprouting 3.470798e-5
GO:0035993 deltoid tuberosity development 3.470798e-5
GO:0006625 protein targeting to peroxisome 3.657391e-5
GO:0016082 synaptic vesicle priming 3.676174e-5
GO:0042773 ATP synthesis coupled electron transport 4.622957e-5
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 4.629919e-5
GO:0035246 peptidyl-arginine N-methylation 4.920979e-5
GO:0060440 trachea formation 4.923855e-5
GO:0051030 snRNA transport 5.018291e-5
GO:0045046 protein import into peroxisome membrane 5.474739e-5
GO:0010464 regulation of mesenchymal cell proliferation 5.706249e-5
GO:0002053 positive regulation of mesenchymal cell proliferation 6.119996e-5
GO:0032225 regulation of synaptic transmission, dopaminergic 6.122694e-5
GO:0032474 otolith morphogenesis 6.179623e-5
GO:0045143 homologous chromosome segregation 6.864038e-5
GO:0071539 protein localization to centrosome 7.453050e-5
GO:0033566 gamma-tubulin complex localization 7.453050e-5
GO:0072198 mesenchymal cell proliferation involved in ureter development 7.453315e-5
GO:0072192 ureter epithelial cell differentiation 7.453315e-5
GO:0072138 mesenchymal cell proliferation involved in ureteric bud development 7.453315e-5
GO:0072101 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway 7.453315e-5
GO:2000005 negative regulation of metanephric S-shaped body morphogenesis 7.453315e-5
GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis 7.453315e-5
GO:2000007 negative regulation of metanephric comma-shaped body morphogenesis 7.453315e-5
GO:0090194 negative regulation of glomerulus development 7.453315e-5
GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis 7.453315e-5
GO:0072200 negative regulation of mesenchymal cell proliferation involved in ureter development 7.453315e-5
GO:0060502 epithelial cell proliferation involved in lung morphogenesis 7.453315e-5
GO:0055020 positive regulation of cardiac muscle fiber development 7.453315e-5
GO:0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway 7.453315e-5
GO:0007500 mesodermal cell fate determination 7.453315e-5
GO:0060503 bud dilation involved in lung branching 7.453315e-5
GO:0048392 intermediate mesodermal cell differentiation 7.453315e-5
GO:0071893 BMP signaling pathway involved in nephric duct formation 7.453315e-5
GO:0061149 BMP signaling pathway involved in ureter morphogenesis 7.453315e-5
GO:0061155 pulmonary artery endothelial tube morphogenesis 7.453315e-5
GO:0061151 BMP signaling pathway involved in renal system segmentation 7.453315e-5
GO:0071044 histone mRNA catabolic process 7.685653e-5
GO:0060319 primitive erythrocyte differentiation 7.834053e-5
GO:0051645 Golgi localization 1.019557e-4
GO:0042026 protein refolding 1.167869e-4
GO:0071777 positive regulation of cell cycle cytokinesis 1.169463e-4
GO:0055005 ventricular cardiac myofibril development 1.226424e-4
GO:0060554 induction of necroptosis of activated-T cells 1.229161e-4
GO:0006713 glucocorticoid catabolic process 1.229161e-4
GO:0010224 response to UV-B 1.262877e-4
GO:0016081 synaptic vesicle docking involved in exocytosis 1.301071e-4
GO:0015969 guanosine tetraphosphate metabolic process 1.389154e-4
GO:0035990 tendon cell differentiation 1.509296e-4
GO:0060390 regulation of SMAD protein import into nucleus 1.578426e-4
GO:0006139 nucleobase-containing compound metabolic process 1.587852e-4
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 1.608843e-4
GO:0045839 negative regulation of mitosis 1.634552e-4
GO:0048597 post-embryonic camera-type eye morphogenesis 1.686908e-4
GO:0018022 peptidyl-lysine methylation 1.748308e-4
GO:0007052 mitotic spindle organization 1.748565e-4
GO:0001777 T cell homeostatic proliferation 1.921648e-4
GO:0032057 negative regulation of translational initiation in response to stress 1.921648e-4
GO:0072594 establishment of protein localization to organelle 2.062866e-4
GO:0018065 protein-cofactor linkage 2.072348e-4
GO:0002028 regulation of sodium ion transport 2.153817e-4
GO:0006412 translation 2.162856e-4
GO:0032353 negative regulation of hormone biosynthetic process 2.235230e-4
GO:0042775 mitochondrial ATP synthesis coupled electron transport 2.250007e-4
GO:0007292 female gamete generation 2.378334e-4
GO:0034776 response to histamine 2.676818e-4
GO:0019858 cytosine metabolic process 2.676818e-4
GO:0048388 endosomal lumen acidification 2.735011e-4
GO:0044091 membrane biogenesis 2.786928e-4
GO:0001880 Mullerian duct regression 2.786928e-4
GO:0009586 rhodopsin mediated phototransduction 2.786928e-4
GO:0030263 apoptotic chromosome condensation 2.788648e-4
GO:0060058 positive regulation of apoptosis involved in mammary gland involution 2.848545e-4
GO:0090271 positive regulation of fibroblast growth factor production 2.876020e-4
GO:0090336 positive regulation of brown fat cell differentiation 2.876020e-4
GO:0090362 positive regulation of platelet-derived growth factor production 2.876020e-4
GO:0070831 basement membrane assembly 2.876020e-4
GO:0008208 C21-steroid hormone catabolic process 2.876020e-4
GO:0016191 synaptic vesicle uncoating 2.876020e-4
GO:0060377 negative regulation of mast cell differentiation 2.876020e-4
GO:0060971 embryonic heart tube left/right pattern formation 2.876020e-4
GO:0006401 RNA catabolic process 3.076008e-4
GO:0048563 post-embryonic organ morphogenesis 3.138851e-4
GO:0009214 cyclic nucleotide catabolic process 3.247903e-4
GO:0001840 neural plate development 3.302381e-4
GO:0001839 neural plate morphogenesis 3.339864e-4
GO:0090224 regulation of spindle organization 3.485780e-4
GO:2000078 positive regulation of type B pancreatic cell development 3.685666e-4
GO:0015886 heme transport 3.685666e-4
GO:0061015 snRNA import into nucleus 3.736464e-4
GO:0017187 peptidyl-glutamic acid carboxylation 3.736464e-4
GO:0048213 Golgi vesicle prefusion complex stabilization 3.736464e-4
GO:0048813 dendrite morphogenesis 3.738672e-4
GO:0006471 protein ADP-ribosylation 3.834258e-4
GO:0060391 positive regulation of SMAD protein import into nucleus 4.078314e-4
GO:0060449 bud elongation involved in lung branching 4.078984e-4
GO:0010613 positive regulation of cardiac muscle hypertrophy 4.135015e-4
GO:0003278 apoptosis involved in heart morphogenesis 4.150843e-4
GO:0031047 gene silencing by RNA 4.200465e-4
GO:0001887 selenium compound metabolic process 4.251206e-4
GO:0060084 synaptic transmission involved in micturition 4.642549e-4
GO:0010933 positive regulation of macrophage tolerance induction 4.642549e-4
GO:0003130 BMP signaling pathway involved in heart induction 4.793263e-4
GO:0060413 atrial septum morphogenesis 4.831169e-4
GO:0006117 acetaldehyde metabolic process 5.226943e-4
GO:0051302 regulation of cell division 5.269963e-4
GO:0009886 post-embryonic morphogenesis 5.284116e-4
GO:0007090 regulation of S phase of mitotic cell cycle 5.284116e-4
GO:0050908 detection of light stimulus involved in visual perception 5.665199e-4
GO:0030219 megakaryocyte differentiation 5.795027e-4
GO:0019509 L-methionine salvage from methylthioadenosine 5.809486e-4
GO:0030002 cellular anion homeostasis 5.811892e-4
GO:0018023 peptidyl-lysine trimethylation 6.143605e-4
GO:0007614 short-term memory 6.241225e-4
GO:0009103 lipopolysaccharide biosynthetic process 6.738303e-4
GO:0006364 rRNA processing 6.934847e-4
GO:0003283 atrial septum development 7.204186e-4
GO:0051588 regulation of neurotransmitter transport 7.461649e-4
GO:0002331 pre-B cell allelic exclusion 7.708987e-4
GO:0070562 regulation of vitamin D receptor signaling pathway 7.771057e-4
GO:0033590 response to cobalamin 7.919550e-4
GO:0046502 uroporphyrinogen III metabolic process 7.919550e-4
GO:0016139 glycoside catabolic process 7.919550e-4
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 7.919550e-4
GO:0010216 maintenance of DNA methylation 8.423709e-4
GO:0051781 positive regulation of cell division 8.699580e-4
GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation 9.020424e-4
GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway 9.020424e-4
GO:0007371 ventral midline determination 9.020424e-4
GO:0060248 detection of cell density by contact stimulus involved in contact inhibition 9.020424e-4
GO:0018125 peptidyl-cysteine methylation 9.020424e-4
GO:0031947 negative regulation of glucocorticoid biosynthetic process 9.257115e-4
GO:0060433 bronchus development 9.380033e-4
GO:0006402 mRNA catabolic process 9.598737e-4
GO:0060046 regulation of acrosome reaction 1.047039e-3
GO:0071034 CUT catabolic process 1.055227e-3
GO:0030174 regulation of DNA-dependent DNA replication initiation 1.055227e-3
GO:0060684 epithelial-mesenchymal cell signaling 1.063599e-3
GO:0061046 regulation of branching involved in lung morphogenesis 1.097732e-3
GO:0051590 positive regulation of neurotransmitter transport 1.097732e-3
GO:0002320 lymphoid progenitor cell differentiation 1.125198e-3
GO:0000087 M phase of mitotic cell cycle 1.132009e-3
GO:0033692 cellular polysaccharide biosynthetic process 1.135704e-3
GO:0030071 regulation of mitotic metaphase/anaphase transition 1.159370e-3
GO:0072098 anterior/posterior pattern specification involved in kidney development 1.200495e-3
GO:0035441 cell migration involved in vasculogenesis 1.200495e-3
GO:0048389 intermediate mesoderm development 1.200495e-3
GO:0090307 spindle assembly involved in mitosis 1.308100e-3
GO:0008033 tRNA processing 1.328487e-3
GO:0042447 hormone catabolic process 1.339144e-3
GO:0051726 regulation of cell cycle 1.406624e-3
GO:0007603 phototransduction, visible light 1.430791e-3
GO:0022403 cell cycle phase 1.453929e-3
GO:0009125 nucleoside monophosphate catabolic process 1.457167e-3
GO:0006086 acetyl-CoA biosynthetic process from pyruvate 1.540546e-3
GO:0016072 rRNA metabolic process 1.564490e-3
GO:0070389 chaperone cofactor-dependent protein refolding 1.594690e-3
GO:0043248 proteasome assembly 1.594690e-3
GO:0071156 regulation of cell cycle arrest 1.617575e-3
GO:0006710 androgen catabolic process 1.632110e-3
GO:0060712 spongiotrophoblast layer development 1.635938e-3
GO:0051584 regulation of dopamine uptake 1.641955e-3
GO:0008334 histone mRNA metabolic process 1.646802e-3
GO:0022410 circadian sleep/wake cycle process 1.741912e-3
GO:0032298 positive regulation of DNA-dependent DNA replication initiation 1.742288e-3
GO:0002502 peptide antigen assembly with MHC class I protein complex 1.742288e-3
GO:0022904 respiratory electron transport chain 1.764147e-3
GO:0031570 DNA integrity checkpoint 1.780646e-3
GO:0061047 positive regulation of branching involved in lung morphogenesis 1.780854e-3
GO:0061154 endothelial tube morphogenesis 1.780854e-3
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1.780854e-3
GO:0010950 positive regulation of endopeptidase activity 1.803916e-3
GO:0000278 mitotic cell cycle 1.813611e-3
GO:0007094 mitotic cell cycle spindle assembly checkpoint 1.877013e-3
GO:0043170 macromolecule metabolic process 1.899927e-3
GO:0019369 arachidonic acid metabolic process 2.017693e-3
GO:0003158 endothelium development 2.080840e-3
GO:0070827 chromatin maintenance 2.107748e-3
GO:0035946 mitochondrial mRNA surveillance 2.107748e-3
GO:0035945 mitochondrial ncRNA surveillance 2.107748e-3
GO:0071174 mitotic cell cycle spindle checkpoint 2.137801e-3
GO:0043314 negative regulation of neutrophil degranulation 2.137801e-3
GO:0043461 proton-transporting ATP synthase complex assembly 2.140405e-3
GO:0042770 signal transduction in response to DNA damage 2.162493e-3
GO:0048070 regulation of developmental pigmentation 2.169099e-3
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade 2.181720e-3
GO:0043060 meiotic metaphase I plate congression 2.234023e-3
GO:0002352 B cell negative selection 2.234023e-3
GO:0019371 cyclooxygenase pathway 2.234023e-3
GO:0071173 spindle assembly checkpoint 2.257616e-3
GO:0072560 type B pancreatic cell maturation 2.272085e-3
GO:0007023 post-chaperonin tubulin folding pathway 2.272085e-3
GO:0045947 negative regulation of translational initiation 2.327965e-3
GO:0035855 megakaryocyte development 2.426213e-3
GO:0060555 induction of necroptosis by extracellular signals 2.434252e-3
GO:0042130 negative regulation of T cell proliferation 2.438556e-3
GO:0042745 circadian sleep/wake cycle 2.459474e-3
GO:0043149 stress fiber assembly 2.462581e-3
GO:0045987 positive regulation of smooth muscle contraction 2.502985e-3
GO:0010888 negative regulation of lipid storage 2.503082e-3
GO:0060040 retinal bipolar neuron differentiation 2.552073e-3
GO:0007067 mitosis 2.572593e-3
GO:0045187 regulation of circadian sleep/wake cycle, sleep 2.702634e-3
GO:0043586 tongue development 2.741335e-3
GO:0071733 transcriptional activation by promoter-enhancer looping 2.782687e-3
GO:0000715 nucleotide-excision repair, DNA damage recognition 2.782687e-3
GO:0014040 positive regulation of Schwann cell differentiation 2.782687e-3
GO:0043525 positive regulation of neuron apoptosis 2.943294e-3
GO:0006298 mismatch repair 2.977634e-3
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 3.020391e-3
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 3.029700e-3
GO:0022900 electron transport chain 3.048162e-3
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.065879e-3
GO:0043137 DNA replication, removal of RNA primer 3.065879e-3
GO:0006119 oxidative phosphorylation 3.074239e-3
GO:0070244 negative regulation of thymocyte apoptosis 3.093780e-3
GO:0010608 posttranscriptional regulation of gene expression 3.097460e-3
GO:0032446 protein modification by small protein conjugation 3.123119e-3
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 3.224050e-3
GO:0000077 DNA damage checkpoint 3.264940e-3
GO:0042053 regulation of dopamine metabolic process 3.291264e-3
GO:0005978 glycogen biosynthetic process 3.315417e-3
GO:0050672 negative regulation of lymphocyte proliferation 3.346765e-3
GO:0033261 regulation of S phase 3.392008e-3
GO:0021904 dorsal/ventral neural tube patterning 3.409965e-3
GO:0003221 right ventricular cardiac muscle tissue morphogenesis 3.422510e-3
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 3.422510e-3
GO:0045933 positive regulation of muscle contraction 3.513223e-3
GO:0055025 positive regulation of cardiac muscle tissue development 3.549972e-3
GO:0051310 metaphase plate congression 3.599809e-3
GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 3.609502e-3
GO:0048102 autophagic cell death 3.681499e-3
GO:0016567 protein ubiquitination 3.736362e-3
GO:0060215 primitive hemopoiesis 3.766283e-3
GO:0045988 negative regulation of striated muscle contraction 3.795771e-3
GO:2000112 regulation of cellular macromolecule biosynthetic process 3.964046e-3
GO:0070664 negative regulation of leukocyte proliferation 3.995634e-3
GO:0006435 threonyl-tRNA aminoacylation 4.029804e-3
GO:0008354 germ cell migration 4.104902e-3
GO:0046931 pore complex assembly 4.145487e-3
GO:0051204 protein insertion into mitochondrial membrane 4.145487e-3
GO:0022007 convergent extension involved in neural plate elongation 4.145487e-3
GO:0071267 L-methionine salvage 4.161496e-3
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 4.161496e-3
GO:0006925 inflammatory cell apoptosis 4.161496e-3
GO:2000344 positive regulation of acrosome reaction 4.189587e-3
GO:0014056 regulation of acetylcholine secretion 4.189587e-3
GO:0031577 spindle checkpoint 4.229995e-3
GO:0051580 regulation of neurotransmitter uptake 4.318884e-3
GO:0031062 positive regulation of histone methylation 4.318884e-3
GO:0048701 embryonic cranial skeleton morphogenesis 4.347524e-3
GO:0035582 negative regulation of BMP signaling pathway by extracellular sequestering of BMP 4.551100e-3
GO:0006285 base-excision repair, AP site formation 4.551100e-3
GO:0033084 regulation of immature T cell proliferation in thymus 4.660096e-3
GO:0090185 negative regulation of kidney development 4.811648e-3
GO:0045079 negative regulation of chemokine biosynthetic process 5.007594e-3
GO:0090072 positive regulation of sodium ion transport via voltage-gated sodium channel activity 5.007594e-3
GO:0006975 DNA damage induced protein phosphorylation 5.007594e-3
GO:0002358 B cell homeostatic proliferation 5.007594e-3
GO:0070585 protein localization in mitochondrion 5.019553e-3
GO:0051252 regulation of RNA metabolic process 5.066895e-3
GO:0017157 regulation of exocytosis 5.111532e-3
GO:0071480 cellular response to gamma radiation 5.123421e-3
GO:0006273 lagging strand elongation 5.179423e-3
GO:0072655 establishment of protein localization in mitochondrion 5.274139e-3
GO:0022402 cell cycle process 5.321618e-3
GO:0002031 G-protein coupled receptor internalization 5.362710e-3
GO:0034453 microtubule anchoring 5.379698e-3
GO:0043313 regulation of neutrophil degranulation 5.388950e-3
GO:0001541 ovarian follicle development 5.411445e-3
GO:0044237 cellular metabolic process 5.454348e-3
GO:0032330 regulation of chondrocyte differentiation 5.485591e-3
GO:0050883 musculoskeletal movement, spinal reflex action 5.553180e-3
GO:0042069 regulation of catecholamine metabolic process 5.583866e-3
GO:0007341 penetration of zona pellucida 5.583866e-3
GO:0019836 hemolysis by symbiont of host erythrocytes 5.621633e-3
GO:0016358 dendrite development 5.651293e-3
GO:0045880 positive regulation of smoothened signaling pathway 5.939441e-3
GO:0043558 regulation of translational initiation in response to stress 5.968639e-3
GO:0050774 negative regulation of dendrite morphogenesis 6.034013e-3
GO:0010940 positive regulation of necrotic cell death 6.034013e-3
GO:0048285 organelle fission 6.071342e-3
GO:0035356 cellular triglyceride homeostasis 6.129761e-3
GO:0010637 negative regulation of mitochondrial fusion 6.129761e-3
GO:0071279 cellular response to cobalt ion 6.129761e-3
GO:0000965 mitochondrial RNA 3'-end processing 6.129761e-3
GO:0000958 mitochondrial mRNA catabolic process 6.129761e-3
GO:0000962 positive regulation of mitochondrial RNA catabolic process 6.129761e-3
GO:0002221 pattern recognition receptor signaling pathway 6.147063e-3
GO:0009584 detection of visible light 6.256197e-3
GO:0000956 nuclear-transcribed mRNA catabolic process 6.272586e-3
GO:0051952 regulation of amine transport 6.346255e-3
GO:0046628 positive regulation of insulin receptor signaling pathway 6.372980e-3
GO:0071985 multivesicular body sorting pathway 6.529413e-3
GO:0070914 UV-damage excision repair 6.529413e-3
GO:0008582 regulation of synaptic growth at neuromuscular junction 6.529413e-3
GO:0016340 calcium-dependent cell-matrix adhesion 6.529413e-3
GO:0032465 regulation of cytokinesis 6.536702e-3
GO:0046885 regulation of hormone biosynthetic process 6.575816e-3
GO:0001964 startle response 6.589326e-3
GO:0070625 zymogen granule exocytosis 6.594523e-3
GO:0071025 RNA surveillance 6.594523e-3
GO:0044314 protein K27-linked ubiquitination 6.594523e-3
GO:0018214 protein carboxylation 6.594523e-3
GO:0048478 replication fork protection 6.594523e-3
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 6.603199e-3
GO:0008653 lipopolysaccharide metabolic process 6.603199e-3
GO:0033083 regulation of immature T cell proliferation 6.729468e-3
GO:0006399 tRNA metabolic process 6.732994e-3
GO:0051303 establishment of chromosome localization 6.736266e-3
GO:0060841 venous blood vessel development 6.745441e-3
GO:0031573 intra-S DNA damage checkpoint 6.766023e-3
GO:0000226 microtubule cytoskeleton organization 6.953910e-3
GO:0045132 meiotic chromosome segregation 6.985057e-3
GO:0061039 ovum-producing ovary development 7.137805e-3
GO:0048569 post-embryonic organ development 7.138346e-3
GO:0045773 positive regulation of axon extension 7.269213e-3
GO:0035372 protein localization to microtubule 7.281233e-3
GO:2000015 regulation of determination of dorsal identity 7.281233e-3
GO:0006283 transcription-coupled nucleotide-excision repair 7.281233e-3
GO:0000085 G2 phase of mitotic cell cycle 7.281233e-3
GO:0003350 pulmonary myocardium development 7.282780e-3
GO:0030728 ovulation 7.340406e-3
GO:0072205 metanephric collecting duct development 7.342514e-3
GO:0008625 induction of apoptosis via death domain receptors 7.342514e-3
GO:0042772 DNA damage response, signal transduction resulting in transcription 7.436660e-3
GO:0010468 regulation of gene expression 7.456933e-3
GO:0031572 G2/M transition DNA damage checkpoint 7.508894e-3
GO:0003222 ventricular trabecular myocardium morphogenesis 7.561908e-3
GO:0035524 proline transmembrane transport 7.561908e-3
GO:0060395 SMAD protein signal transduction 7.621090e-3
GO:0032467 positive regulation of cytokinesis 7.673895e-3
GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 7.782454e-3
GO:0090184 positive regulation of kidney development 7.851685e-3
GO:0048842 positive regulation of axon extension involved in axon guidance 8.093466e-3
GO:0000189 MAPK import into nucleus 8.093466e-3
GO:0006355 regulation of transcription, DNA-dependent 8.159948e-3
GO:0048255 mRNA stabilization 8.183670e-3
GO:0051571 positive regulation of histone H3-K4 methylation 8.266073e-3
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 8.266073e-3
GO:0002651 positive regulation of tolerance induction to self antigen 8.266073e-3
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 8.266073e-3
GO:0007131 reciprocal meiotic recombination 8.408862e-3
GO:0072190 ureter urothelium development 8.424835e-3
GO:0031077 post-embryonic camera-type eye development 8.469570e-3
GO:0007346 regulation of mitotic cell cycle 8.477998e-3
GO:0017158 regulation of calcium ion-dependent exocytosis 8.522401e-3
GO:0051954 positive regulation of amine transport 8.742524e-3
GO:0032494 response to peptidoglycan 8.888745e-3
GO:0050482 arachidonic acid secretion 8.966108e-3
GO:0061156 pulmonary artery morphogenesis 9.367030e-3
GO:0021578 hindbrain maturation 9.367030e-3
GO:0090329 regulation of DNA-dependent DNA replication 9.438969e-3
GO:0001570 vasculogenesis 9.476353e-3
GO:0055117 regulation of cardiac muscle contraction 9.503686e-3
GO:0090270 regulation of fibroblast growth factor production 9.617161e-3
GO:0090084 negative regulation of inclusion body assembly 9.617161e-3
GO:0001844 protein insertion into mitochondrial membrane involved in induction of apoptosis 9.617161e-3
GO:0072498 embryonic skeletal joint development 9.656037e-3
GO:0006627 protein processing involved in protein targeting to mitochondrion 9.884206e-3
GO:0003094 glomerular filtration 9.884206e-3
GO:0002575 basophil chemotaxis 9.884206e-3
GO:0006090 pyruvate metabolic process 9.923643e-3
GO:0030258 lipid modification 1.010989e-2
GO:0000279 M phase 1.032294e-2
GO:0071478 cellular response to radiation 1.035581e-2
GO:2000467 positive regulation of glycogen (starch) synthase activity 1.039275e-2
GO:0015824 proline transport 1.053757e-2
GO:0010159 specification of organ position 1.053757e-2
GO:0061312 BMP signaling pathway involved in heart development 1.055551e-2
GO:0042254 ribosome biogenesis 1.084598e-2
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1.092089e-2
GO:0010556 regulation of macromolecule biosynthetic process 1.105924e-2
GO:0001885 endothelial cell development 1.107980e-2
GO:0060285 ciliary cell motility 1.111251e-2
GO:0035095 behavioral response to nicotine 1.111251e-2
GO:0006417 regulation of translation 1.124295e-2
GO:0060926 pacemaker cell development 1.144725e-2
GO:0060932 His-Purkinje system cell differentiation 1.144725e-2
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1.144725e-2
GO:0031497 chromatin assembly 1.148719e-2
GO:0006984 ER-nucleus signaling pathway 1.157845e-2
GO:0021771 lateral geniculate nucleus development 1.188587e-2
GO:0032185 septin cytoskeleton organization 1.209077e-2
GO:0006281 DNA repair 1.212198e-2
GO:0002904 positive regulation of B cell apoptosis 1.251889e-2
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 1.265325e-2
GO:0055014 atrial cardiac muscle cell development 1.275875e-2
GO:0038007 netrin-activated signaling pathway 1.275875e-2
GO:0032055 negative regulation of translation in response to stress 1.275875e-2
GO:0008585 female gonad development 1.275940e-2
GO:0015992 proton transport 1.287075e-2
GO:0002758 innate immune response-activating signal transduction 1.333192e-2
GO:0070936 protein K48-linked ubiquitination 1.344672e-2
GO:0006974 response to DNA damage stimulus 1.358719e-2
GO:0009435 NAD biosynthetic process 1.360596e-2
GO:0043923 positive regulation by host of viral transcription 1.372953e-2
GO:0043967 histone H4 acetylation 1.392852e-2
GO:0042048 olfactory behavior 1.419057e-2
GO:0019532 oxalate transport 1.419057e-2
GO:0035162 embryonic hemopoiesis 1.419119e-2
GO:0032350 regulation of hormone metabolic process 1.426189e-2
GO:0006818 hydrogen transport 1.449442e-2
GO:0060434 bronchus morphogenesis 1.456215e-2
GO:0046070 dGTP metabolic process 1.456215e-2
GO:0090287 regulation of cellular response to growth factor stimulus 1.466528e-2
GO:0010898 positive regulation of triglyceride catabolic process 1.467872e-2
GO:0010611 regulation of cardiac muscle hypertrophy 1.471988e-2
GO:0032227 negative regulation of synaptic transmission, dopaminergic 1.475578e-2
GO:0046717 acid secretion 1.485304e-2
GO:0007051 spindle organization 1.492961e-2
GO:0001886 endothelial cell morphogenesis 1.494718e-2
GO:0070997 neuron death 1.511240e-2
GO:0042220 response to cocaine 1.546477e-2
GO:0001975 response to amphetamine 1.549173e-2
GO:0035249 synaptic transmission, glutamatergic 1.555181e-2
GO:0072385 minus-end-directed organelle transport along microtubule 1.557699e-2
GO:0043148 mitotic spindle stabilization 1.557699e-2
GO:0006408 snRNA export from nucleus 1.557699e-2
GO:0048845 venous blood vessel morphogenesis 1.567595e-2
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 1.598399e-2
GO:0090030 regulation of steroid hormone biosynthetic process 1.599042e-2
GO:0070541 response to platinum ion 1.605600e-2
GO:0048814 regulation of dendrite morphogenesis 1.626435e-2
GO:0009082 branched chain family amino acid biosynthetic process 1.638135e-2
GO:0090361 regulation of platelet-derived growth factor production 1.652861e-2
GO:0021750 vestibular nucleus development 1.652861e-2
GO:0010936 negative regulation of macrophage cytokine production 1.652861e-2
GO:0021679 cerebellar molecular layer development 1.652861e-2
GO:0021590 cerebellum maturation 1.652861e-2
GO:0034441 plasma lipoprotein particle oxidation 1.672565e-2
GO:0002842 positive regulation of T cell mediated immune response to tumor cell 1.672565e-2
GO:0002645 positive regulation of tolerance induction 1.683199e-2